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"PSMA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I261", "map_id": "Q8I261", "name": "PSMB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0108000", "map_id": "PF3D7_0108000", "name": "PSMB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJU4", "map_id": "Q8IJU4", "name": "PSMF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1010100", "map_id": "PF3D7_1010100", "name": "PSMF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IM66", "map_id": "Q8IM66", "name": "PSMD11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1402300", "map_id": "PF3D7_1402300", "name": "PSMD11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKH3", "map_id": "Q8IKH3", "name": "PSMD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1466300", "map_id": "PF3D7_1466300", "name": "PSMD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKC9", "map_id": "Q8IKC9", "name": "PSMB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1470900", "map_id": "PF3D7_1470900", "name": "PSMB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I374", "map_id": "Q8I374", "name": "PSME3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0907700", "map_id": "PF3D7_0907700", "name": "PSME3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I6T3", "map_id": "Q8I6T3", "name": "PSMB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1328100", "map_id": "PF3D7_1328100", "name": "PSMB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K7U1", "map_id": "A0A5K1K7U1", "name": "PSMB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0518300", "map_id": "PF3D7_0518300", "name": "PSMB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEQ1", "map_id": "Q8IEQ1", "name": "PSMC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1306400", "map_id": "PF3D7_1306400", "name": "PSMC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77379", "map_id": "O77379", "name": "PSMD9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0317800", "map_id": "PF3D7_0317800", "name": "PSMD9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4U5", "map_id": "Q8I4U5", "name": "PSMC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1248900", "map_id": "PF3D7_1248900", "name": "PSMC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77345", "map_id": "O77345", "name": "PSMD8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0312300", "map_id": "PF3D7_0312300", "name": "PSMD8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1V1", "map_id": "Q8I1V1", "name": "PSMC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0413600", "map_id": "PF3D7_0413600", "name": "PSMC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I323", "map_id": "Q8I323", "name": "PSMD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0912900", "map_id": "PF3D7_0912900", "name": "PSMD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8II60", "map_id": "Q8II60", "name": "PSMC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1130400", "map_id": "PF3D7_1130400", "name": "PSMC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAR3", "map_id": "Q8IAR3", "name": "PSMA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0807500", "map_id": "PF3D7_0807500", "name": "PSMA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBI3", "map_id": "Q8IBI3", "name": "PSMA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0727400", "map_id": "PF3D7_0727400", "name": "PSMA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDG3", "map_id": "Q8IDG3", "name": "PSMA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1353800", "map_id": "PF3D7_1353800", "name": "PSMA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8II71", "map_id": "Q8II71", "name": "PSMD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1129200", "map_id": "PF3D7_1129200", "name": "PSMD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEK3", "map_id": "Q8IEK3", "name": "PSMC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1311500", "map_id": "PF3D7_1311500", "name": "PSMC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAR6", "map_id": "Q8IAR6", "name": "PSMD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0807800", "map_id": "PF3D7_0807800", "name": "PSMD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77396", "map_id": "O77396", "name": "PSMA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0317000", "map_id": "PF3D7_0317000", "name": "PSMA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJW0", "map_id": "Q8IJW0", "name": "PSMC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1008400", "map_id": "PF3D7_1008400", "name": "PSMC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K9F3", "map_id": "A0A5K1K9F3", "name": "PSMD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1338100", "map_id": "PF3D7_1338100", "name": "PSMD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KST3", "map_id": "C6KST3", "name": "PSMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0608500", "map_id": "PF3D7_0608500", "name": "PSMA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10686976", "map_id": "none", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10686544", "map_id": "none", "name": "MCM2-7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10686974", "map_id": "none", "name": "Mcm4,6,7 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10686542", "map_id": "Q8ILR7", "name": "MCM2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686527", "map_id": "Q8I5T4", "name": "MCM5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686517", "map_id": "Q8I3J5", "name": "MCM3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10686962", "map_id": "none", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10686407", "map_id": "Q8I469", "name": "CDC6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686949", "map_id": "Q8I469", "name": "phospho-p-CDC6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686959", "map_id": "none", "name": "CCNA:p-T160-CDK2,CCNE:p-T160-CDK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IC23", "map_id": "Q8IC23", "name": "CCNF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0704700", "map_id": "PF3D7_0704700", "name": "CCNF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10686966", "map_id": "none", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10686964", "map_id": "Q8I469", "name": "phospho-p-CDC6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10686972", "map_id": "none", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10686970", "map_id": "none", "name": "ubiquitinated Cdc6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10691078", "map_id": "none", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9677997", "map_id": "CHEBI:41941", "name": "DOPAC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71284", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9677992", "map_id": "CHEBI:545959", "name": "HVA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_174369", "map_id": "CHEBI:17230", "name": "HCYS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691067", "map_id": "Q8IKF4", "name": "COMT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_1468300", "map_id": "PF3D7_1468300", "name": "LRTOMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703494", "map_id": "none", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_29438", "map_id": "CHEBI:15996", "name": "GTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10699285", "map_id": "none", "name": "RAN:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7KQK6", "map_id": "Q7KQK6", "name": "RAN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1117700", "map_id": "PF3D7_1117700", "name": "RAN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29420", "map_id": "CHEBI:17552", "name": "GDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10703486", "map_id": "none", "name": "RAN:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10703491", "map_id": "C0H4M6", "name": "RCC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "false" }, { "id": "PF3D7_0711500", "map_id": "PF3D7_0711500", "name": "RCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703498", "map_id": "none", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9624879", "map_id": "none", "name": "Nuclear envelope vesicle", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10703496", "map_id": "none", "name": "RAN:GTP:Nuclear envelope vesicles", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10691051", "map_id": "none", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_374935", "map_id": "CHEBI:18357", "name": "NAd", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_209789", "map_id": "CHEBI:18357", "name": "NAd", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691048", "map_id": "none", "name": "SLC22A1,SLC22A2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8I611", "map_id": "Q8I611", "name": "SLC22A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1203400", "map_id": "PF3D7_1203400", "name": "SLC22A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691300", "map_id": "none", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30991", "map_id": "CHEBI:16356", "name": "cGMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113578", "map_id": "CHEBI:17345", "name": "GMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10691297", "map_id": "none", "name": "cGMP phosphodiesterases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IKD3", "map_id": "Q8IKD3", "name": "PDEdelta", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1470500", "map_id": "PF3D7_1470500", "name": "PDEdelta", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I6Z7", "map_id": "Q8I6Z7", "name": "PDEbeta", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1321500.1", "map_id": "PF3D7_1321500.1", "name": "PDEbeta", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "B3FEM7", "map_id": "B3FEM7", "name": "PDEgamma", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1321600", "map_id": "PF3D7_1321600", "name": "PDEgamma", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691242", "map_id": "none", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29468", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29368", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_202124", "map_id": "CHEBI:16480", "name": "NO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29968", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691239", "map_id": "none", "name": "NOS1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H553", "map_id": "C0H553", "name": "phospho-2xPalmC-MyrG-p-S1177-NOS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0923200", "map_id": "PF3D7_0923200", "name": "phospho-2xPalmC-MyrG-p-S1177-NOS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699877", "map_id": "none", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_113592", "map_id": "CHEBI:30616", "name": "ATP", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1524165", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629751", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29370", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699874", "map_id": "none", "name": "PIK3C3:PIK3R4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "Q8IB64", "map_id": "Q8IB64", "name": "PIK3R4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0823000", "map_id": "PF3D7_0823000", "name": "PIK3R4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3V5", "map_id": "Q8I3V5", "name": "PIK3C3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0515300", "map_id": "PF3D7_0515300", "name": "PIK3C3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703237", "map_id": "none", "name": "SEPHS2 phosphorylates H2Se to form SELP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5357660", "map_id": "CHEBI:16503", "name": "H2Se", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29356", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29372", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8959518", "map_id": "CHEBI:16144", "name": "SELP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76577", "map_id": "CHEBI:16027", "name": "AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703234", "map_id": "Q8I348", "name": "SEPHS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0910400", "map_id": "PF3D7_0910400", "name": "SEPHS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694885", "map_id": "none", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694412", "map_id": "none", "name": "Calcineurin (CaN)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_216785", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:29034", "map_id": "CHEBI:29034", "name": "CHEBI:29034", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAM8", "map_id": "Q8IAM8", "name": "PPP3CA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0802800", "map_id": "PF3D7_0802800", "name": "PPP3CA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKV9", "map_id": "Q8IKV9", "name": "PPP3R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1451700", "map_id": "PF3D7_1451700", "name": "PPP3R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690526", "map_id": "none", "name": "CALM1:4xCa2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_74016", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P62203", "map_id": "P62203", "name": "CALM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0323", "map_id": "PF14_0323", "name": "CALM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694857", "map_id": "none", "name": "Calcineurin:Calmodulin (CaN:CaM)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10695764", "map_id": "none", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10695758", "map_id": "none", "name": "NFATC1:CaN:CaM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10695762", "map_id": "none", "name": "NFATC1:CaN:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10695726", "map_id": "none", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695720", "map_id": "none", "name": "pT298-NLK dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7KQK7", "map_id": "Q7KQK7", "name": "MAPK7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1113900", "map_id": "PF3D7_1113900", "name": "MAPK7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695724", "map_id": "none", "name": "pT298-NLK dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10693951", "map_id": "none", "name": "Ubiquitinated DVL is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693946", "map_id": "none", "name": "ub-DVL:CUL3:KLHL12:RBX1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDQ2", "map_id": "Q8IDQ2", "name": "KBTBD8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1343700", "map_id": "PF3D7_1343700", "name": "KBTBD8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KTD3", "map_id": "C6KTD3", "name": "CUL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693938", "map_id": "none", "name": "CUL3:KLHL12:RBX1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693949", "map_id": "none", "name": "DVL is ubiquitinated by CUL3:KLHL12:RBX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693942", "map_id": "none", "name": "DVL:CUL3:KLHL12:RBX1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10690643", "map_id": "none", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113518", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10690340", "map_id": "none", "name": "p-T1218, Y220 MAPK7 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113550", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10690391", "map_id": "none", "name": "MAPK7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10690640", "map_id": "none", "name": "ERK-specific DUSP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IKS8", "map_id": "Q8IKS8", "name": "DUSP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1455100", "map_id": "PF3D7_1455100", "name": "DUSP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690343", "map_id": "none", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10690313", "map_id": "none", "name": "Ribosomal protein S6 kinase", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I4W3", "map_id": "Q8I4W3", "name": "RPS6KA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1246900", "map_id": "PF3D7_1246900", "name": "RPS6KA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690338", "map_id": "none", "name": "Phospho-Ribosomal protein S6 kinase", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697570", "map_id": "none", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697549", "map_id": "none", "name": "Homologues of p-S115 MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A5K1K8V9", "map_id": "A0A5K1K8V9", "name": "phospho-p-T182 MAPKAPK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1338900", "map_id": "PF3D7_1338900", "name": "phospho-p-T182 MAPKAPK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIV3", "map_id": "Q8IIV3", "name": "phospho-p-T200-CAMK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1104900", "map_id": "PF3D7_1104900", "name": "phospho-p-T200-CAMK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I534", "map_id": "Q8I534", "name": "phospho-p-T182 MAPKAPK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697568", "map_id": "none", "name": "Homologues of p-S115 MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10698160", "map_id": "none", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698156", "map_id": "none", "name": "Homologues of p-T182 MAPKAPK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10695314", "map_id": "O96123", "name": "DNAJB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0201800", "map_id": "PF3D7_0201800", "name": "DNAJB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698158", "map_id": "none", "name": "p-T182 MAPKAPK5:DNAJB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O96123", "map_id": "O96123", "name": "DNAJB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698170", "map_id": "none", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698167", "map_id": "none", "name": "p-T182 MAPKAPK5:p-S149,S151, S171 DNAJB1 ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697560", "map_id": "none", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697538", "map_id": "none", "name": "Homologues of MAPKAPK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10697557", "map_id": "none", "name": "Homologues of PRKACA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I719", "map_id": "Q8I719", "name": "PKG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1436600", "map_id": "PF3D7_1436600", "name": "PKG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7K6A0", "map_id": "Q7K6A0", "name": "PRKACA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0934800", "map_id": "PF3D7_0934800", "name": "PRKACA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4P1", "map_id": "C0H4P1", "name": "PRKACA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688929", "map_id": "none", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688922", "map_id": "none", "name": "UNG-1:(Ura:Gua)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILU6", "map_id": "Q8ILU6", "name": "UNG-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1415000", "map_id": "PF3D7_1415000", "name": "UNG-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688926", "map_id": "none", "name": "UNG-1:AP-dsDNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_29554", "map_id": "CHEBI:17568", "name": "Ura", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688945", "map_id": "none", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688940", "map_id": "none", "name": "NTHL1:Tg-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "C6KSY9", "map_id": "C6KSY9", "name": "NTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0614800", "map_id": "PF3D7_0614800", "name": "NTH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_110223", "map_id": "CHEBI:29128", "name": "Tg", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10688942", "map_id": "none", "name": "NTHL1:AP-dsDNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688966", "map_id": "none", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688963", "map_id": "none", "name": "NTHL1:FapyA-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5637659", "map_id": "CHEBI:27983", "name": "FapyA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688936", "map_id": "none", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688933", "map_id": "none", "name": "UNG-1:5-OHU-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110216", "map_id": "CHEBI:29115", "name": "5-OHU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688952", "map_id": "none", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688949", "map_id": "none", "name": "NTHL1:Cg-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110225", "map_id": "CHEBI:29127", "name": "Cg", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688959", "map_id": "none", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688956", "map_id": "none", "name": "NTHL1:DHU-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30140", "map_id": "CHEBI:15901", "name": "DHU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688990", "map_id": "none", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688987", "map_id": "none", "name": "OGG1:FapyG-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I2Y2", "map_id": "Q8I2Y2", "name": "OGG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0917100", "map_id": "PF3D7_0917100", "name": "OGG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688982", "map_id": "none", "name": "OGG1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5636006", "map_id": "CHEBI:29145", "name": "FapyG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10703130", "map_id": "none", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10703122", "map_id": "none", "name": "Homologues of ULK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IHR5", "map_id": "Q8IHR5", "name": "ULK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1145200", "map_id": "PF3D7_1145200", "name": "ULK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H563", "map_id": "C0H563", "name": "ULK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703128", "map_id": "none", "name": "Homologues of ULK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10699391", "map_id": "none", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_109276", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_171126", "map_id": "CHEBI:17855", "name": "TAGs", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_174675", "map_id": "CHEBI:18035", "name": "DAGs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_6789319", "map_id": "CHEBI:33575", "name": "RCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10699388", "map_id": "none", "name": "keratinocyte LIPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q8II98", "map_id": "Q8II98", "name": "LIPF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1126600", "map_id": "PF3D7_1126600", "name": "LIPF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691303", "map_id": "none", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30389", "map_id": "CHEBI:17489", "name": "cAMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10691295", "map_id": "none", "name": "Phosphodiesterases, dual (cAMP, cGMP) activity", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10695969", "map_id": "none", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10694938", "map_id": "none", "name": "SUMO1:C93-UBE2I", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I301", "map_id": "Q8I301", "name": "SUMO1-K14-UBE2I", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0915100", "map_id": "PF3D7_0915100", "name": "SUMO1-K14-UBE2I", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I444", "map_id": "Q8I444", "name": "K14-UBE2I-G97-SUMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0505800", "map_id": "PF3D7_0505800", "name": "K14-UBE2I-G97-SUMO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687012", "map_id": "P61074", "name": "PCNA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF13_0328", "map_id": "PF13_0328", "name": "PCNA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695967", "map_id": "none", "name": "SUMO1:PCNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P61074", "map_id": "P61074", "name": "PCNA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694930", "map_id": "Q8I301", "name": "UBE2I", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10696010", "map_id": "none", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696001", "map_id": "Q8ILC8", "name": "TOP2B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1433500", "map_id": "PF3D7_1433500", "name": "SUMO1-K-TOP2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696008", "map_id": "none", "name": "SUMO1:TOP2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILC8", "map_id": "Q8ILC8", "name": "SUMO1-K-TOP2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695999", "map_id": "none", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695989", "map_id": "Q8ILC8", "name": "TOP2A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695997", "map_id": "none", "name": "SUMO1:TOP2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10696015", "map_id": "none", "name": "PIAS4 SUMOylates TOP2A with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695835", "map_id": "none", "name": "UBE2I:SUMO2,UBE2I:SUMO3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10696013", "map_id": "Q8ILC8", "name": "SUMO2,3-TOP2A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695666", "map_id": "A0A5K1K9G1", "name": "PIAS4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1360700", "map_id": "PF3D7_1360700", "name": "SUMO1-K35-PIAS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696030", "map_id": "none", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696020", "map_id": "Q8I3Z9", "name": "TOP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0510500", "map_id": "PF3D7_0510500", "name": "SUMO1-K117-TOP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696028", "map_id": "none", "name": "SUMO1:TOP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I3Z9", "map_id": "Q8I3Z9", "name": "SUMO1-K117-TOP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690228", "map_id": "none", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111707", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196786", "map_id": "CHEBI:15905", "name": "PPanK", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111294", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196834", "map_id": "CHEBI:15769", "name": "PPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690225", "map_id": "none", "name": "2xPPCS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9U0G7", "map_id": "Q9U0G7", "name": "PPCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0412300", "map_id": "PF3D7_0412300", "name": "PPCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690248", "map_id": "none", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196767", "map_id": "CHEBI:16858", "name": "PPANT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113528", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690245", "map_id": "none", "name": "3xPPCDC:3xFMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IAZ8", "map_id": "Q8IAZ8", "name": "PPCDC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0816100", "map_id": "PF3D7_0816100", "name": "PPCDC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_73524", "map_id": "CHEBI:17621", "name": "FMN", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10694915", "map_id": "none", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10694902", "map_id": "Q8I444", "name": "SUMO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10694897", "map_id": "none", "name": "UBA2:SAE1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IHS2", "map_id": "Q8IHS2", "name": "SAE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1144500", "map_id": "PF3D7_1144500", "name": "SAE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I553", "map_id": "Q8I553", "name": "SUMO1-C173-UBA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1237000", "map_id": "PF3D7_1237000", "name": "SUMO1-C173-UBA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_164121", "map_id": "CHEBI:16027", "name": "AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_113541", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10694912", "map_id": "none", "name": "SUMO1:UBA2:SAE1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10694941", "map_id": "none", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10689122", "map_id": "none", "name": "Displacement of OGG1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689114", "map_id": "O97240", "name": "APEX1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0305600", "map_id": "PF3D7_0305600", "name": "APEX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689116", "map_id": "none", "name": "APEX1:AP-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O97240", "map_id": "O97240", "name": "APEX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688971", "map_id": "Q8I2Y2", "name": "OGG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689120", "map_id": "none", "name": "Displacement of NTHL1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688913", "map_id": "C6KSY9", "name": "NTH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689126", "map_id": "none", "name": "Displacement of MPG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689014", "map_id": "none", "name": "MPG:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IKG6", "map_id": "Q8IKG6", "name": "MPG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1467100", "map_id": "PF3D7_1467100", "name": "MPG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688976", "map_id": "Q8IKG6", "name": "MPG", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689124", "map_id": "none", "name": "Displacement of MUTYH glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689005", "map_id": "none", "name": "MUTYH:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A143ZYC4", "map_id": "A0A143ZYC4", "name": "MUTYH-6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1129500", "map_id": "PF3D7_1129500", "name": "MUTYH-6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689001", "map_id": "none", "name": "MUTYH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689118", "map_id": "none", "name": "Displacement of UNG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688920", "map_id": "Q8ILU6", "name": "UNG-1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694851", "map_id": "none", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29804", "map_id": "CHEBI:29103", "name": "K+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_74126", "map_id": "CHEBI:29103", "name": "K+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10694848", "map_id": "none", "name": "Slo3 Channel", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8ILA3", "map_id": "Q8ILA3", "name": "KCNU1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1436100", "map_id": "PF3D7_1436100", "name": "KCNU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695003", "map_id": "none", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10694993", "map_id": "none", "name": "MeK5-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_29478", "map_id": "CHEBI:16842", "name": "CH2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10694995", "map_id": "none", "name": "Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695000", "map_id": "Q8I5T5", "name": "KDM1A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1211600", "map_id": "PF3D7_1211600", "name": "KDM1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697178", "map_id": "none", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696046", "map_id": "none", "name": "Me2K5-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10696062", "map_id": "none", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113671", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_113685", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159942", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159939", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696059", "map_id": "none", "name": "KDM5A-D", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IAT4", "map_id": "Q8IAT4", "name": "KDM5D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0809900", "map_id": "PF3D7_0809900", "name": "KDM5D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697164", "map_id": "none", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696441", "map_id": "none", "name": "Me3K5-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695575", "map_id": "none", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695561", "map_id": "none", "name": "Acetylated core histone octamer", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695567", "map_id": "none", "name": "Core histone octamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IIV2", "map_id": "Q8IIV2", "name": "HIST1H4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1105000", "map_id": "PF3D7_1105000", "name": "HIST1H4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5566518", "map_id": "CHEBI:30089", "name": "acetate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695572", "map_id": "Q8IJW3", "name": "HDAC10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1008000", "map_id": "PF3D7_1008000", "name": "HDAC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696930", "map_id": "none", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_77087", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_77502", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696443", "map_id": "Q8IDE8", "name": "SMYD3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1355300", "map_id": "PF3D7_1355300", "name": "SMYD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696961", "map_id": "none", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696040", "map_id": "none", "name": "MeK37-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696949", "map_id": "none", "name": "Me2K37-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696101", "map_id": "none", "name": "Homologues of SMYD2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IIL1", "map_id": "Q8IIL1", "name": "SMYD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1115200", "map_id": "PF3D7_1115200", "name": "SMYD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I352", "map_id": "Q8I352", "name": "SMYD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDE8", "map_id": "Q8IDE8", "name": "SMYD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696688", "map_id": "none", "name": "SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689874", "map_id": "Q8IIV2", "name": "HIST1H4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10694646", "map_id": "Q8IIV2", "name": "MeK-HIST1H4A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10694706", "map_id": "Q8I1Z0", "name": "SETD8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0403900", "map_id": "PF3D7_0403900", "name": "SETD8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696104", "map_id": "none", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10696446", "map_id": "none", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696247", "map_id": "none", "name": "Me2aR3-histone H3, MeR3-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695392", "map_id": "none", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113560", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2485002", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695365", "map_id": "Q8IIV2", "name": "AcK5,12-HIST1H4A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695389", "map_id": "none", "name": "HAT1:RBBP7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IE52", "map_id": "Q8IE52", "name": "RBBP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1433300", "map_id": "PF3D7_1433300", "name": "RBBP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILD0", "map_id": "Q8ILD0", "name": "RBBP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I238", "map_id": "Q8I238", "name": "RBBP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4A7", "map_id": "C0H4A7", "name": "HAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0416400", "map_id": "PF3D7_0416400", "name": "HAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696439", "map_id": "none", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696420", "map_id": "none", "name": "MeR30-histone H2A, Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696437", "map_id": "none", "name": "Me2aR30-histone H2A, MeR30-histone H2A", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696177", "map_id": "Q8IHP7", "name": "PRMT6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1147300", "map_id": "PF3D7_1147300", "name": "PRMT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696182", "map_id": "none", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696172", "map_id": "Q8IIV2", "name": "MeR4-HIST1H4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696179", "map_id": "none", "name": "PRMT1,PRMT6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IHP7", "map_id": "Q8IHP7", "name": "PRMT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILK1", "map_id": "Q8ILK1", "name": "PRMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1426200", "map_id": "PF3D7_1426200", "name": "PRMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696293", "map_id": "none", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696273", "map_id": "none", "name": "MeR12-histone H2A, Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696290", "map_id": "none", "name": "Me2aR12-histone H2A, MeR12-histone H2A", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695008", "map_id": "Q8ILK1", "name": "PRMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10696219", "map_id": "none", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696199", "map_id": "none", "name": "MeR4-histone H2A, Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696216", "map_id": "none", "name": "Me2aR4-histone H2A, MeR4-histone H2A", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10696249", "map_id": "none", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696235", "map_id": "none", "name": "MeR3-histone H3, Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10696335", "map_id": "none", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695387", "map_id": "none", "name": "Homologues of RBBP7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10696333", "map_id": "none", "name": "RBBP7:Replicative histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10696321", "map_id": "none", "name": "Me2sR3-histone H3", "type": "inhibitor", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10697183", "map_id": "none", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697181", "map_id": "Q8IIV2", "name": "Me2aR4-HIST1H4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10697206", "map_id": "none", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697198", "map_id": "Q8ILV5", "name": "ADRM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1414000", "map_id": "PF3D7_1414000", "name": "ADRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697200", "map_id": "none", "name": "ADRM1:26S proteasome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILV5", "map_id": "Q8ILV5", "name": "ADRM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698293", "map_id": "none", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698284", "map_id": "none", "name": "UCHL3,SENP8:NEDD8(1-88)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IKM8", "map_id": "Q8IKM8", "name": "UCHL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1460400", "map_id": "PF3D7_1460400", "name": "UCHL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEI4", "map_id": "Q8IEI4", "name": "NEDD8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1313000", "map_id": "PF3D7_1313000", "name": "NEDD8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698288", "map_id": "none", "name": "UCHL3,SENP8:NEDD8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10698290", "map_id": "Q8IEI4", "name": "NEDD8(77-88)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10697204", "map_id": "none", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697193", "map_id": "Q8IIJ6", "name": "UCH54", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1117100", "map_id": "PF3D7_1117100", "name": "UCH54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697202", "map_id": "none", "name": "ADRM1:26S proteasome:UCHL5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIJ6", "map_id": "Q8IIJ6", "name": "UCH54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698267", "map_id": "none", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698262", "map_id": "none", "name": "UCHL1,UCHL3:Ub-Lys", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1131871", "map_id": "CHEBI:32551", "name": "L-lysine", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10698264", "map_id": "none", "name": "UCHL1,UCHL3:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10687165", "map_id": "none", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29548", "map_id": "CHEBI:16077", "name": "G1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30537", "map_id": "CHEBI:58225", "name": "G6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687122", "map_id": "none", "name": "PGM:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_29926", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q8IJS0", "map_id": "Q8IJS0", "name": "PGM2L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1012500", "map_id": "PF3D7_1012500", "name": "PGM2L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687018", "map_id": "none", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687005", "map_id": "none", "name": "RFC Heteropentamer:RNA primer-DNA primer:origin duplex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IKK4", "map_id": "Q8IKK4", "name": "RFC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1463200", "map_id": "PF3D7_1463200", "name": "RFC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I512", "map_id": "Q8I512", "name": "RFC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1241700", "map_id": "PF3D7_1241700", "name": "RFC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96260", "map_id": "O96260", "name": "RFC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0218000", "map_id": "PF3D7_0218000", "name": "RFC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96271", "map_id": "O96271", "name": "RFC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0219600", "map_id": "PF3D7_0219600", "name": "RFC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIQ1", "map_id": "Q8IIQ1", "name": "RFC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1111100", "map_id": "PF3D7_1111100", "name": "RFC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKK3", "map_id": "Q8IKK3", "name": "POLA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1463300", "map_id": "PF3D7_1463300", "name": "POLA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7KQM1", "map_id": "Q7KQM1", "name": "PRIM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0366", "map_id": "PF14_0366", "name": "PRIM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H531", "map_id": "C0H531", "name": "PRIM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0910900", "map_id": "PF3D7_0910900", "name": "PRIM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9U0H1", "map_id": "Q9U0H1", "name": "POLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0411900", "map_id": "PF3D7_0411900", "name": "POLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687014", "map_id": "none", "name": "PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687016", "map_id": "none", "name": "RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10687007", "map_id": "none", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10686939", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687003", "map_id": "none", "name": "RFC Heteropentamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10687022", "map_id": "none", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687020", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex:PCNA ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10687059", "map_id": "none", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687055", "map_id": "A0A5K1K9F2", "name": "DNA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1333900", "map_id": "PF3D7_1333900", "name": "DNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687050", "map_id": "none", "name": "Processive complex:Okazaki fragment:Flap:RPA heterotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O77321", "map_id": "O77321", "name": "POLD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0308000", "map_id": "PF3D7_0308000", "name": "POLD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7KQL4", "map_id": "Q7KQL4", "name": "POLD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1017000", "map_id": "PF3D7_1017000", "name": "POLD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6S3I6", "map_id": "C6S3I6", "name": "RPA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1442100", "map_id": "PF3D7_1442100", "name": "RPA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIN9", "map_id": "Q8IIN9", "name": "RPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1112400", "map_id": "PF3D7_1112400", "name": "RPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687057", "map_id": "none", "name": "Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A5K1K9F2", "map_id": "A0A5K1K9F2", "name": "DNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687071", "map_id": "none", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687061", "map_id": "none", "name": "Processive complex:Okazaki fragments:Remaining Flap", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687063", "map_id": "none", "name": "Processive complex:nicked DNA from adjacent Okazaki fragments", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687068", "map_id": "Q7K734", "name": "FEN1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PFD0420c", "map_id": "PFD0420c", "name": "FEN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687079", "map_id": "none", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_68452", "map_id": "none", "name": "Okazaki fragment", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_69172", "map_id": "none", "name": "ligated okazaki fragment", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10687076", "map_id": "Q8IES4", "name": "LIG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1304100", "map_id": "PF3D7_1304100", "name": "LIG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687046", "map_id": "none", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687042", "map_id": "none", "name": "Processive complex:Okazaki fragment complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687044", "map_id": "none", "name": "Processive complex:Okazaki fragment:Flap", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689433", "map_id": "none", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689420", "map_id": "Q8IJZ7", "name": "phospho-p-RPL13A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1004000", "map_id": "PF3D7_1004000", "name": "RPL13A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689429", "map_id": "none", "name": "43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I5H4", "map_id": "Q8I5H4", "name": "PABPC1", "type": "complex_component", "sub_type": 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"inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97266", "map_id": "O97266", "name": "EIF4E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0315100", "map_id": "PF3D7_0315100", "name": "EIF4E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAZ3", "map_id": "Q8IAZ3", "name": "phospho-p-S221,S318-ELAVL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0815600", "map_id": "PF3D7_0815600", "name": "phospho-p-S221,S318-ELAVL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3I5", "map_id": "Q8I3I5", "name": "EIF3E", "type": "complex_component", "sub_type": 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"compartment_display": "none" }, { "id": "PF3D7_1212700", "map_id": "PF3D7_1212700", "name": "EIF3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1Q5", "map_id": "Q8I1Q5", "name": "EIF3M", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0418200", "map_id": "PF3D7_0418200", "name": "EIF3M", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJW4", "map_id": "Q8IJW4", "name": "EIF3D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1007900", "map_id": "PF3D7_1007900", "name": "EIF3D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBT2", "map_id": "Q8IBT2", "name": "EIF3I", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0716800", "map_id": "PF3D7_0716800", "name": "EIF3I", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5Y3", "map_id": "Q8I5Y3", "name": "EIF3C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1206200", "map_id": "PF3D7_1206200", "name": "EIF3C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97249", "map_id": "O97249", "name": "RPS12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0307100", "map_id": 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"compartment_display": "none" }, { "id": "PF3D7_0719700", "map_id": "PF3D7_0719700", "name": "RPS10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97248", "map_id": "O97248", "name": "RPS23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0306900", "map_id": "PF3D7_0306900", "name": "RPS23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3R0", "map_id": "Q8I3R0", "name": "RPS9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0520000", "map_id": "PF3D7_0520000", "name": "RPS9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77381", "map_id": "O77381", "name": "RPS11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0317600", "map_id": "PF3D7_0317600", "name": "RPS11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHT2", "map_id": "Q8IHT2", "name": "EIF1AX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1143400", "map_id": "PF3D7_1143400", "name": "EIF1AX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJT9", "map_id": "Q8IJT9", "name": "EIF2S2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1010600", "map_id": "PF3D7_1010600", "name": "EIF2S2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILY9", "map_id": "Q8ILY9", "name": "EIF2S3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1410600", "map_id": "PF3D7_1410600", "name": "EIF2S3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBH7", "map_id": "Q8IBH7", "name": "EIF2S1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0728000", "map_id": "PF3D7_0728000", "name": "EIF2S1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689431", "map_id": "none", "name": "phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJZ7", "map_id": "Q8IJZ7", "name": "RPL13A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689437", "map_id": "none", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688213", "map_id": "none", "name": "60S ribosomal complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3B0", "map_id": "Q8I3B0", "name": "RPL32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0903900", "map_id": "PF3D7_0903900", "name": "RPL32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I463", "map_id": "Q8I463", "name": "RPL31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": 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"compartment_display": "none" }, { "id": "Q8IE82", "map_id": "Q8IE82", "name": "RPL23A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1323400", "map_id": "PF3D7_1323400", "name": "RPL23A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE09", "map_id": "Q8IE09", "name": "RPL23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1331800", "map_id": "PF3D7_1331800", "name": "RPL23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILV2", "map_id": "Q8ILV2", "name": "RPL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1414300", "map_id": "PF3D7_1414300", "name": "RPL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILK3", "map_id": "Q8ILK3", "name": "RPL21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1426000", "map_id": "PF3D7_1426000", "name": "RPL21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSY6", "map_id": "C6KSY6", "name": "RPL19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0614500", "map_id": "PF3D7_0614500", "name": "RPL19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE85", "map_id": "Q8IE85", "name": "RPL9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1323100", "map_id": "PF3D7_1323100", "name": "RPL9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDS6", "map_id": "Q8IDS6", "name": "RPL18A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1341200", "map_id": "PF3D7_1341200", "name": "RPL18A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688008", "map_id": "Q8IJZ7", "name": "RPL13A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689435", "map_id": "none", "name": "60s ribosomal complex lacking L13a subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10698371", "map_id": "none", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29418", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1981162", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10698368", "map_id": "Q8IBH9", "name": "ATP13A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_0727800", "map_id": "PF3D7_0727800", "name": "ATP13A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691233", "map_id": "none", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_114521", "compartment_display": "platelet dense tubular network membrane" }, { "id": "species_427899", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114580", "compartment_display": "platelet dense tubular network lumen", "complex": "false" }, { "id": "species_139827", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114580", "compartment_display": "platelet dense tubular network lumen", "complex": "false" }, { "id": "species_10691230", "map_id": "none", "name": "ATP2A1-3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114521", "compartment_display": "platelet dense tubular network membrane", "complex": "true" }, { "id": "Q76NN8", "map_id": "Q76NN8", "name": "ATP2A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1211900", "map_id": "PF3D7_1211900", "name": "ATP2A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A143ZZK9", "map_id": "A0A143ZZK9", "name": "ATP2A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693014", "map_id": "none", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_947588", "map_id": "none", "name": "APLs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane", "complex": "true" }, { "id": "species_1500646", "map_id": "CHEBI:18303", "name": "PS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500581", "map_id": "CHEBI:16038", "name": "PE", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_947594", "map_id": "none", "name": "APLs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947586", "compartment_display": "external side of plasma membrane", "complex": "true" }, { "id": "species_10692986", "map_id": "none", "name": "P-type ATPases type IV", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IKF1", "map_id": "Q8IKF1", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1468600", "map_id": "PF3D7_1468600", "name": "ATP11C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77368", "map_id": "O77368", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHY1", "map_id": "Q8IHY1", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5L4", "map_id": "Q8I5L4", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691562", "map_id": "none", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_156540", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_111875", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10691559", "map_id": "none", "name": "ATP2A1-3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10691208", "map_id": "none", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_74112", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10691205", "map_id": "none", "name": "ATP2B1-4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A5K1K8L6", "map_id": "A0A5K1K8L6", "name": "ATP2B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1348800", "map_id": "PF3D7_1348800", "name": "ATP2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698376", "map_id": "none", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692450", "map_id": "CHEBI:36916", "name": "cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692484", "map_id": "CHEBI:36916", "name": "cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10698373", "map_id": "Q8I3U7", "name": "ATP13A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "PF3D7_0516100", "map_id": "PF3D7_0516100", "name": "ATP13A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696494", "map_id": "none", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5252122", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5252016", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10696491", "map_id": "none", "name": "ATP13A4, 5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8I3U7", "map_id": "Q8I3U7", "name": "ATP13A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699216", "map_id": "none", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10699209", "map_id": "none", "name": "Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I241", "map_id": "Q8I241", "name": "POLR2I", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0110400", "map_id": "PF3D7_0110400", "name": "POLR2I", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ID59", "map_id": "Q8ID59", "name": "POLR2E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1364800", "map_id": "PF3D7_1364800", "name": "POLR2E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5R8", "map_id": "Q8I5R8", "name": "POLR2H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1213700", "map_id": "PF3D7_1213700", "name": "POLR2H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77315", "map_id": "O77315", "name": "POLR2F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0303300", "map_id": "PF3D7_0303300", "name": "POLR2F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96236", "map_id": "O96236", "name": "POLR2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0215700", "map_id": "PF3D7_0215700", "name": "POLR2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77375", "map_id": "O77375", "name": "phospho-p-S5-POLR2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0318200", "map_id": "PF3D7_0318200", "name": "phospho-p-S5-POLR2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IER7", "map_id": "Q8IER7", "name": "POLR2J", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF13_0023", "map_id": "PF13_0023", "name": "POLR2J", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDR2", "map_id": "Q8IDR2", "name": "POLR2K", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1342700", "map_id": "PF3D7_1342700", "name": "POLR2K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96150", "map_id": "O96150", "name": "POLR2D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0205500", "map_id": "PF3D7_0205500", "name": "POLR2D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IC08", "map_id": "Q8IC08", "name": "POLR2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0708100", "map_id": "PF3D7_0708100", "name": "POLR2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJC9", "map_id": "Q8IJC9", "name": "POLR2G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1027400", "map_id": "PF3D7_1027400", "name": "POLR2G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJ31", "map_id": "Q8IJ31", "name": "ERCC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1037600", "map_id": "PF3D7_1037600", "name": "ERCC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4Y8", "map_id": "Q8I4Y8", "name": "GTF2H4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1244200", "map_id": "PF3D7_1244200", "name": "GTF2H4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDG5", "map_id": "Q8IDG5", "name": "GTF2H3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1353500", "map_id": "PF3D7_1353500", "name": "GTF2H3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKK0", "map_id": "Q8IKK0", "name": "CCNH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1463700", "map_id": "PF3D7_1463700", "name": "CCNH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3Y3", "map_id": "Q8I3Y3", "name": "MNAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0512300", "map_id": "PF3D7_0512300", "name": "MNAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL51", "map_id": "Q8IL51", "name": "GTF2H5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1441900", "map_id": "PF3D7_1441900", "name": "GTF2H5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2H7", "map_id": "Q8I2H7", "name": "ERCC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0934100", "map_id": "PF3D7_0934100", "name": "ERCC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEG6", "map_id": "Q8IEG6", "name": "GTF2H2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1314900", "map_id": "PF3D7_1314900", "name": "GTF2H2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6781829", "map_id": "CHEBI:17972", "name": "ribonucleoside triphosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10699213", "map_id": "none", "name": "Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10699211", "map_id": "none", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687612", "map_id": "none", "name": "RNA Polymerase II holoenzyme complex (unphosphorylated)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10688666", "map_id": "none", "name": "TFIIH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5688114", "map_id": "none", "name": "Distorted dsDNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10691010", "map_id": "none", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691000", "map_id": "none", "name": "Homologues of DNM1L", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IHR4", "map_id": "Q8IHR4", "name": "DNM1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1218500", "map_id": "PF3D7_1218500", "name": "DNM1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJ32", "map_id": "Q8IJ32", "name": "DNM1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5M3", "map_id": "Q8I5M3", "name": "DNM1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10691008", "map_id": "none", "name": "Homologues of DNM1L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10690941", "map_id": "none", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10690937", "map_id": "none", "name": "HMGB1/HMGB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I616", "map_id": "Q8I616", "name": "HMGB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1202900", "map_id": "PF3D7_1202900", "name": "HMGB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29428", "map_id": "none", "name": "DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10690939", "map_id": "none", "name": "HMGB1/HMGB2- bound chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10703624", "map_id": "none", "name": "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5679042", "map_id": "none", "name": "BMG,BDG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:18392", "map_id": "CHEBI:18392", "name": "CHEBI:18392", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16427", "map_id": "CHEBI:16427", "name": "CHEBI:16427", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5679034", "map_id": "none", "name": "BMG,BDG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10692753", "map_id": "none", "name": "ABCG2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8ILJ9", "map_id": "Q8ILJ9", "name": "HC-ABCG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1426500", "map_id": "PF3D7_1426500", "name": "HC-ABCG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690066", "map_id": "none", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159549", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70958", "map_id": "CHEBI:57292", "name": "SUCC-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113529", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29374", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_189466", "map_id": "CHEBI:356416", "name": "dALA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29376", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10690063", "map_id": "none", "name": "ALAS1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I4X1", "map_id": "Q8I4X1", "name": "PXLP-ALAS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1246100", "map_id": "PF3D7_1246100", "name": "PXLP-ALAS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_189444", "map_id": "CHEBI:17627", "name": "heme", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10690082", "map_id": "none", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_190157", "map_id": "CHEBI:28766", "name": "URO1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_190128", "map_id": "CHEBI:28607", "name": "COPRO1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690035", "map_id": "none", "name": "2xUROD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KSS1", "map_id": "C6KSS1", "name": "UROD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0607300", "map_id": "PF3D7_0607300", "name": "UROD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690018", "map_id": "none", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189461", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189411", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189481", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189480", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189478", "map_id": "CHEBI:15435", "name": "PPGEN9", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10690015", "map_id": "none", "name": "2xCPO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q8IHU1", "map_id": "Q8IHU1", "name": "CPOX(132-454)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1142400", "map_id": "PF3D7_1142400", "name": "CPOX(132-454)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690080", "map_id": "none", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_190173", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690045", "map_id": "none", "name": "8x(ALAD:Zn2+)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IL68", "map_id": "Q8IL68", "name": "ALAD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1440300", "map_id": "PF3D7_1440300", "name": "ALAD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690078", "map_id": "none", "name": "8xALAD:Pb2+:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_391232", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29426", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690048", "map_id": "none", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189489", "map_id": "CHEBI:356416", "name": "dALA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_189464", "map_id": "CHEBI:58126", "name": "PBG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690038", "map_id": "none", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189407", "map_id": "CHEBI:15437", "name": "URO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_189455", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694949", "map_id": "none", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162257", "map_id": "CHEBI:17407", "name": "FPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113521", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2995328", "map_id": "CHEBI:24480", "name": "heme O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159450", "map_id": "CHEBI:29888", "name": "PPi", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10694946", "map_id": "Q8I0W6", "name": "COX10(?-443)", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_0519300", "map_id": "PF3D7_0519300", "name": "COX10(?-443)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692756", "map_id": "none", "name": "ABCG2 tetramer transports heme from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_71185", "map_id": "CHEBI:17627", "name": "heme", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_917877", "map_id": "CHEBI:17627", "name": "heme", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10690008", "map_id": "none", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189449", "map_id": "CHEBI:57845", "name": "HMBL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31633", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690005", "map_id": "none", "name": "HMBS:DIPY", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I5V3", "map_id": "Q8I5V3", "name": "HMBS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1209600", "map_id": "PF3D7_1209600", "name": "HMBS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36319", "map_id": "CHEBI:36319", "name": "CHEBI:36319", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694957", "map_id": "none", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2995348", "map_id": "CHEBI:24479", "name": "heme A", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10694954", "map_id": "Q8ILB4", "name": "COX15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_1435000", "map_id": "PF3D7_1435000", "name": "COX15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690028", "map_id": "none", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189463", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10690025", "map_id": "none", "name": "2xPPOX:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q8IJC3", "map_id": "Q8IJC3", "name": "PPOX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1028100", "map_id": "PF3D7_1028100", "name": "PPOX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29386", "map_id": "CHEBI:16238", "name": "FAD", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10690076", "map_id": "none", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_189487", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113531", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10690073", "map_id": "none", "name": "2x(FECH:2Fe-2S cluster)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8ID58", "map_id": "Q8ID58", "name": "FECH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1364900", "map_id": "PF3D7_1364900", "name": "FECH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689488", "map_id": "none", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689484", "map_id": "Q8IKW5", "name": "EEF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1451100", "map_id": "PF3D7_1451100", "name": "EEF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689486", "map_id": "none", "name": "eEF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IKW5", "map_id": "Q8IKW5", "name": "EEF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701428", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10696892", "map_id": "none", "name": "ARF4:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7KQL3", "map_id": "Q7KQL3", "name": "ARF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF10_0203", "map_id": "PF10_0203", "name": "ARF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701424", "map_id": "none", "name": "RAB1:GTP:GBF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q8IL42", "map_id": "Q8IL42", "name": "GBF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1442900", "map_id": "PF3D7_1442900", "name": "GBF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3W9", "map_id": "Q8I3W9", "name": "RAB1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0513800", "map_id": "PF3D7_0513800", "name": "RAB1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K8H7", "map_id": "A0A5K1K8H7", "name": "RAB1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701426", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10701434", "map_id": "none", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10701274", "map_id": "none", "name": "coatomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8II16", "map_id": "Q8II16", "name": "ARCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1134800", "map_id": "PF3D7_1134800", "name": "ARCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHR6", "map_id": "Q8IHR6", "name": "COPG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1145100", "map_id": "PF3D7_1145100", "name": "COPG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILG6", "map_id": "Q8ILG6", "name": "COPB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1429800", "map_id": "PF3D7_1429800", "name": "COPB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1T3", "map_id": "Q8I1T3", "name": "COPZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0415400", "map_id": "PF3D7_0415400", "name": "COPZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I390", "map_id": "Q8I390", "name": "COPB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0905900", "map_id": "PF3D7_0905900", "name": "COPB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4T1", "map_id": "C0H4T1", "name": "COPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0808400", "map_id": "PF3D7_0808400", "name": "COPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSR5", "map_id": "C6KSR5", "name": "COPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0606700", "map_id": "PF3D7_0606700", "name": "COPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701430", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10701432", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP:coatomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10701439", "map_id": "none", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10701213", "map_id": "Q8IL42", "name": "GBF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10701422", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10701437", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10701485", "map_id": "none", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10698591", "map_id": "none", "name": "SNAPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I0X0", "map_id": "Q8I0X0", "name": "NAPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0509000", "map_id": "PF3D7_0509000", "name": "NAPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701483", "map_id": "none", "name": "SEC22B:STX18:USE1L:BNIP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "C0H5E1", "map_id": "C0H5E1", "name": "STX18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1326800", "map_id": "PF3D7_1326800", "name": "STX18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K9E7", "map_id": "A0A5K1K9E7", "name": "BNIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1316800", "map_id": "PF3D7_1316800", "name": "BNIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97323", "map_id": "O97323", "name": "SEC22B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0320100", "map_id": "PF3D7_0320100", "name": "SEC22B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698587", "map_id": "none", "name": "NSF hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77313", "map_id": "O77313", "name": "NSF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0303000", "map_id": "PF3D7_0303000", "name": "NSF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701481", "map_id": "none", "name": "SEC22B:STX18:USE1:BNIP1L:3xSNAPs:NSF hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10694883", "map_id": "none", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694861", "map_id": "none", "name": "NFAT:CaN:CaM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10694881", "map_id": "none", "name": "NFAT:CaN:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10702926", "map_id": "none", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10702912", "map_id": "none", "name": "PIP4K2B dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I239", "map_id": "Q8I239", "name": "PIP4K2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0110600", "map_id": "PF3D7_0110600", "name": "PIP4K2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702923", "map_id": "none", "name": "p-S326-PIP4K2B dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10692168", "map_id": "Q8IBK6", "name": "phospho-p-S207,T211-MAP2K6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0724600", "map_id": "PF3D7_0724600", "name": "phospho-p-S207,T211-MAP2K6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701516", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6810408", "map_id": "CHEBI:16500", "name": "PI5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_6810412", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10701513", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10701668", "map_id": "none", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_549167", "map_id": "CHEBI:17855", "name": "TAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8876730", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76103", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10701665", "map_id": "O96266", "name": "PNPLA4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0218600", "map_id": "PF3D7_0218600", "name": "PNPLA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689972", "map_id": "none", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113596", "map_id": "CHEBI:16238", "name": "FAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_188458", "map_id": "CHEBI:15978", "name": "G3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_31649", "map_id": "CHEBI:17877", "name": "FADH2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_188451", "map_id": "CHEBI:57642", "name": "DHAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10689969", "map_id": "O97245", "name": "GPD2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_0306400", "map_id": "PF3D7_0306400", "name": "GPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701673", "map_id": "none", "name": "PNPLA5 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701670", "map_id": "O96266", "name": "PNPLA5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10701676", "map_id": "none", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2534407", "map_id": "CHEBI:17616", "name": "atR-PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8848337", "map_id": "CHEBI:7896", "name": "PALM(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30209", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10697441", "map_id": "none", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5682283", "map_id": "CHEBI:18059", "name": "lipids", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5229279", "map_id": "CHEBI:18059", "name": "lipids", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10697438", "map_id": "O97278", "name": "ABCA12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0319700", "map_id": "PF3D7_0319700", "name": "ABCA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693632", "map_id": "none", "name": "ABCAs mediate lipid influx", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_171149", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_176478", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693627", "map_id": "none", "name": "ABCA cholesterol transporters", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10690928", "map_id": "none", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_216762", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "false" }, { "id": "species_171095", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10690925", "map_id": "none", "name": "ABCG1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10690921", "map_id": "none", "name": "ABCG5:ABCG8 transports sterols from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_265784", "map_id": "none", "name": "sterols", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:26125", "map_id": "CHEBI:26125", "name": "CHEBI:26125", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_265781", "map_id": "none", "name": "sterols", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10690918", "map_id": "none", "name": "ABCG5:ABCG8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10701647", "map_id": "none", "name": "ABCA5 transports CHOL from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8848047", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10701644", "map_id": "O97278", "name": "ABCA5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "reaction_10693647", "map_id": "none", "name": "ABCG4 may mediate cholesterol efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693644", "map_id": "none", "name": "ABCG4 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10693630", "map_id": "none", "name": "ABCAs mediate lipid efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10697468", "map_id": "none", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2133233", "compartment_display": "lamellar body membrane" }, { "id": "species_5684863", "map_id": "none", "name": "PC, PG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_194276", "map_id": "CHEBI:16110", "name": "phosphatidylcholines", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_1483256", "map_id": "CHEBI:17517", "name": "PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5684869", "map_id": "none", "name": "PC, PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_80738", "compartment_display": "lamellar body", "complex": "true" }, { "id": "species_10697465", "map_id": "O97278", "name": "ABCA3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2133233", "compartment_display": "lamellar body membrane", "complex": "false" }, { "id": "reaction_10696352", "map_id": "none", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696348", "map_id": "Q8IIE9", "name": "ABCF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1121700", "map_id": "PF3D7_1121700", "name": "ABCF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687881", "map_id": "none", "name": "EIF2S1:EIF2S2:EIF2S3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10696350", "map_id": "none", "name": "ABCF1:EIF2S1:EIF2S2:EIF2S3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIE9", "map_id": "Q8IIE9", "name": "ABCF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693652", "map_id": "none", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1131652", "map_id": "CHEBI:35703", "name": "a xenobiotic", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1467459", "map_id": "CHEBI:35703", "name": "a xenobiotic", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10693649", "map_id": "O97278", "name": "ABCA8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10696331", "map_id": "none", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5223341", "map_id": "none", "name": "23mer peptide", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5223344", "map_id": "none", "name": "23mer peptide", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10696328", "map_id": "none", "name": "ABCB9 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "Q8IHR3", "map_id": "Q8IHR3", "name": "TAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1145500", "map_id": "PF3D7_1145500", "name": "TAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693657", "map_id": "none", "name": "ABCA4 mediates atRAL transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74000", "compartment_display": "photoreceptor outer segment membrane" }, { "id": "species_2466098", "map_id": "CHEBI:17898", "name": "atRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_975622", "map_id": "CHEBI:17898", "name": "atRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693654", "map_id": "O97278", "name": "ABCA4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10693640", "map_id": "none", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1454930", "map_id": "CHEBI:25696", "name": "organic anion", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1454919", "map_id": "CHEBI:25696", "name": "organic anion", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10693637", "map_id": "Q9U0N4", "name": "ABCC10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0112200", "map_id": "PF3D7_0112200", "name": "ABCC10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697434", "map_id": "none", "name": "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697425", "map_id": "none", "name": "4xPALM-C-ABCA1 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O97278", "map_id": "O97278", "name": "ABCA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697431", "map_id": "none", "name": "4xPALM-C-p-2S-ABCA1 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10689280", "map_id": "none", "name": "Homologues of PRKACA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697436", "map_id": "none", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10697421", "map_id": "none", "name": "4xPALM-C-ABCA1 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10690889", "map_id": "none", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_194236", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_171076", "map_id": "CHEBI:17002", "name": "CHEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10690886", "map_id": "C6KTC8", "name": "LCAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "PF3D7_0629300", "map_id": "PF3D7_0629300", "name": "LCAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692450", "map_id": "none", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29514", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_432019", "map_id": "CHEBI:16199", "name": "Urea", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10692447", "map_id": "none", "name": "AQP9,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8II36", "map_id": "Q8II36", "name": "AQP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1132800", "map_id": "PF3D7_1132800", "name": "AQP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692436", "map_id": "none", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10692433", "map_id": "none", "name": "AQP0,1,2,3,4,5,7,8,9,10,11,12A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "C0H4T7", "map_id": "C0H4T7", "name": "MIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0810400", "map_id": "PF3D7_0810400", "name": "MIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692452", "map_id": "none", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10692443", "map_id": "none", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10692441", "map_id": "none", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_192438", "map_id": "CHEBI:17754", "name": "glycerol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_76116", "map_id": "CHEBI:17754", "name": "Glycerol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692438", "map_id": "none", "name": "AQP3,7,9,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692445", "map_id": "none", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10691955", "map_id": "none", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691952", "map_id": "none", "name": "AQP3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10691777", "map_id": "none", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691774", "map_id": "none", "name": "p-S256-AQP2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10691802", "map_id": "none", "name": "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691795", "map_id": "none", "name": "AQP2 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "species_10691799", "map_id": "none", "name": "p-S256-AQP2 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "reaction_10703161", "map_id": "none", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689282", "map_id": "none", "name": "PKA tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7KQK0", "map_id": "Q7KQK0", "name": "PRKAR2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1223100", "map_id": "PF3D7_1223100", "name": "PRKAR2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689284", "map_id": "none", "name": "PKA tetramer:4xcAMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10691769", "map_id": "none", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691754", "map_id": "none", "name": "AQP1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10689288", "map_id": "none", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689286", "map_id": "none", "name": "cAMP:PKA regulatory subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10691784", "map_id": "none", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691781", "map_id": "none", "name": "AQP4 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10691757", "map_id": "none", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10691767", "map_id": "none", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691764", "map_id": "none", "name": "AQP9 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10691791", "map_id": "none", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691788", "map_id": "none", "name": "AQP7 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10696562", "map_id": "none", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109496", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10696559", "map_id": "C0H599", "name": "MRS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_1304200.2", "map_id": "PF3D7_1304200.2", "name": "MRS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696578", "map_id": "none", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114632", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10696575", "map_id": "B9ZSI6", "name": "MAGT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0107700", "map_id": "PF3D7_0107700", "name": "MAGT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696554", "map_id": "none", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696551", "map_id": "none", "name": "NIPAs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A144A2U1", "map_id": "A0A144A2U1", "name": "NIPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1467000", "map_id": "PF3D7_1467000", "name": "NIPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBA9", "map_id": "Q8IBA9", "name": "NIPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696573", "map_id": "none", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696570", "map_id": "B9ZSI6", "name": "TUSC3(1-348)", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10693563", "map_id": "none", "name": "AQP1 tetramer transports CO2 from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237009", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10691843", "map_id": "none", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_351626", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_435347", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_71067", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10691840", "map_id": "Q8I3M7", "name": "SLC11A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0523800", "map_id": "PF3D7_0523800", "name": "SLC11A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691859", "map_id": "none", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_437295", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_209799", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691856", "map_id": "Q8IL79", "name": "SLC31A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_1439000", "map_id": "PF3D7_1439000", "name": "SLC31A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691873", "map_id": "none", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_158417", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10691870", "map_id": "none", "name": "SLC39A1-4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "C6KST8", "map_id": "C6KST8", "name": "SLC39A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0609100", "map_id": "PF3D7_0609100", "name": "SLC39A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691851", "map_id": "none", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10691848", "map_id": "Q8IBU1", "name": "SLC30A8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "PF3D7_0715900", "map_id": "PF3D7_0715900", "name": "SLC30A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691838", "map_id": "none", "name": "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_445829", "map_id": "none", "name": "Divalent metals transported by NRAMP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_445832", "map_id": "none", "name": "Divalent metals transported by NRAMP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "true" }, { "id": "species_1470067", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_10691835", "map_id": "Q8I3M7", "name": "SLC11A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "reaction_10691830", "map_id": "none", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_446589", "map_id": "none", "name": "MATE substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:8428", "map_id": "CHEBI:8428", "name": "CHEBI:8428", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:46020", "map_id": "CHEBI:46020", "name": "CHEBI:46020", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:42820", "map_id": "CHEBI:42820", "name": "CHEBI:42820", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:641", "map_id": "CHEBI:641", "name": "CHEBI:641", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:6801", "map_id": "CHEBI:6801", "name": "CHEBI:6801", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16737", "map_id": "CHEBI:16737", "name": "CHEBI:16737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_446597", "map_id": "none", "name": "MATE substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10691827", "map_id": "none", "name": "MATE1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O96209", "map_id": "O96209", "name": "SLC47A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0212800", "map_id": "PF3D7_0212800", "name": "SLC47A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692562", "map_id": "none", "name": "OCT3 mediates renal uptake of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549255", "map_id": "none", "name": "OCT3 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:47781", "map_id": "CHEBI:47781", "name": "CHEBI:47781", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:47499", "map_id": "CHEBI:47499", "name": "CHEBI:47499", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:46631", "map_id": "CHEBI:46631", "name": "CHEBI:46631", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_549326", "map_id": "none", "name": "OCT3 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692535", "map_id": "Q8I611", "name": "SLC22A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10692533", "map_id": "none", "name": "SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_164988", "map_id": "CHEBI:17126", "name": "CAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_74113", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_30235", "map_id": "CHEBI:17126", "name": "CAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_83910", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692530", "map_id": "none", "name": "SLC22A4, 5,15,16", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692516", "map_id": "none", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549264", "map_id": "none", "name": "OCT1 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_380873", "map_id": "CHEBI:18243", "name": "DA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:28918", "map_id": "CHEBI:28918", "name": "CHEBI:28918", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_204635", "map_id": "CHEBI:16610", "name": "SPM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:15854", "map_id": "CHEBI:15854", "name": "CHEBI:15854", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:65133", "map_id": "CHEBI:65133", "name": "CHEBI:65133", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:18295", "map_id": "CHEBI:18295", "name": "CHEBI:18295", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_353560", "map_id": "CHEBI:15746", "name": "SPN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6798162", "map_id": "CHEBI:15354", "name": "Cho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "CHEBI:16797", "map_id": "CHEBI:16797", "name": "CHEBI:16797", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_549250", "map_id": "none", "name": "OCT1 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692513", "map_id": "none", "name": "OCT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692538", "map_id": "none", "name": "OCT3 mediates renal clearance of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10692553", "map_id": "none", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549266", "map_id": "none", "name": "OCT2 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_209914", "map_id": "CHEBI:28790", "name": "5HT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_351164", "map_id": "CHEBI:17431", "name": "AGM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:31941", "map_id": "CHEBI:31941", "name": "CHEBI:31941", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_549237", "map_id": "none", "name": "OCT2 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10692521", "map_id": "none", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549261", "map_id": "CHEBI:4828", "name": "ERGT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_549260", "map_id": "CHEBI:4828", "name": "ERGT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692518", "map_id": "Q8I611", "name": "SLC22A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10692575", "map_id": "none", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_597604", "map_id": "none", "name": "SLC22A18 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_597623", "map_id": "none", "name": "SLC22A18 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692572", "map_id": "C0H4E1", "name": "SLC22A18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0516500", "map_id": "PF3D7_0516500", "name": "SLC22A18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692540", "map_id": "none", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10692524", "map_id": "none", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10692560", "map_id": "none", "name": "OAT2 and OAT4 mediate transport of sulphate conjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29406", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_561071", "map_id": "none", "name": "OAT2/4 sulfate conjugate substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:16814", "map_id": "CHEBI:16814", "name": "CHEBI:16814", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17474", "map_id": "CHEBI:17474", "name": "CHEBI:17474", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_561062", "map_id": "none", "name": "OAT2/4 sulfate conjugate substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_561075", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10692557", "map_id": "none", "name": "OAT2/4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692551", "map_id": "none", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_561049", "map_id": "none", "name": "OAT1-3 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:104011", "map_id": "CHEBI:104011", "name": "CHEBI:104011", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2453", "map_id": "CHEBI:2453", "name": "CHEBI:2453", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_561078", "map_id": "none", "name": "OAT1-3 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692548", "map_id": "none", "name": "OAT1-3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692567", "map_id": "none", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29708", "map_id": "CHEBI:422", "name": "LACT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429056", "map_id": "CHEBI:17775", "name": "urate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_373863", "map_id": "CHEBI:422", "name": "LACT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_30034", "map_id": "CHEBI:17775", "name": "urate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10692564", "map_id": "Q8I611", "name": "SLC22A12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691904", "map_id": "none", "name": "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691901", "map_id": "O96181", "name": "SLC6A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0209600", "map_id": "PF3D7_0209600", "name": "SLC6A12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691015", "map_id": "none", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266029", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_29424", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691012", "map_id": "O96181", "name": "SLC6A18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691076", "map_id": "none", "name": "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_159362", "map_id": "CHEBI:18243", "name": "DA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691017", "map_id": "O96181", "name": "SLC6A6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691913", "map_id": "none", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_188972", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352003", "map_id": "CHEBI:59888", "name": "GABA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352011", "map_id": "CHEBI:59888", "name": "GABA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_352022", "map_id": "CHEBI:17996", "name": "Cl-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691910", "map_id": "none", "name": "SLC6A GABA transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O96181", "map_id": "O96181", "name": "SLC6A12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691023", "map_id": "none", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352007", "map_id": "none", "name": "ligands of SLC6A12 (BGT-1)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:16958", "map_id": "CHEBI:16958", "name": "CHEBI:16958", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17750", "map_id": "CHEBI:17750", "name": "CHEBI:17750", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:48950", "map_id": "CHEBI:48950", "name": "CHEBI:48950", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_351982", "map_id": "none", "name": "ligands of SLC6A12 (BGT-1)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10690400", "map_id": "O96181", "name": "SLC6A12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691020", "map_id": "none", "name": "SLC6A6-mediated uptake of taurine and beta-alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352024", "map_id": "none", "name": "ligands of SLC6A6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:15891", "map_id": "CHEBI:15891", "name": "CHEBI:15891", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_352019", "map_id": "none", "name": "ligands of SLC6A6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10691058", "map_id": "none", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_375458", "map_id": "none", "name": "neutral amino acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_29432", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:57912", "map_id": "CHEBI:57912", "name": "CHEBI:57912", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29472", "map_id": "CHEBI:58359", "name": "L-Gln", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:58045", "map_id": "CHEBI:58045", "name": "CHEBI:58045", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_200736", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:57427", "map_id": "CHEBI:57427", "name": "CHEBI:57427", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_379705", "map_id": "CHEBI:57844", "name": "L-Met", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "CHEBI:58315", "map_id": "CHEBI:58315", "name": "CHEBI:58315", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29502", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:57762", "map_id": "CHEBI:57762", "name": "CHEBI:57762", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_375481", "map_id": "none", "name": "neutral amino acids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10691055", "map_id": "O96181", "name": "SLC6A19", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691921", "map_id": "none", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352033", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_113538", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690402", "map_id": "O96181", "name": "SLC6A7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691063", "map_id": "none", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_375468", "map_id": "none", "name": "SLC6A14 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:32513", "map_id": "CHEBI:32513", "name": "CHEBI:32513", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_375459", "map_id": "none", "name": "SLC6A14 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10691060", "map_id": "O96181", "name": "SLC6A14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691028", "map_id": "none", "name": "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691025", "map_id": "O96181", "name": "SLC6A20", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691930", "map_id": "none", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691927", "map_id": "none", "name": "SLC6A5,9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10691033", "map_id": "none", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352051", "map_id": "none", "name": "ligands of SLC6A15", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_379717", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "CHEBI:57926", "map_id": "CHEBI:57926", "name": "CHEBI:57926", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29642", "map_id": "CHEBI:58048", "name": "L-Asn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:18240", "map_id": "CHEBI:18240", "name": "CHEBI:18240", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_352048", "map_id": "none", "name": "ligands of SLC6A15", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10691030", "map_id": "O96181", "name": "SLC6A15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691948", "map_id": "none", "name": "Cho transports from the extracellular space to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_264638", "map_id": "CHEBI:15354", "name": "Cho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_264618", "map_id": "CHEBI:15354", "name": "Cho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691945", "map_id": "none", "name": "CTL1-5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8ILE6", "map_id": "Q8ILE6", "name": "SLC44A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1431900", "map_id": "PF3D7_1431900", "name": "SLC44A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702179", "map_id": "none", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2162252", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162265", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_71285", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702176", "map_id": "Q8I513", "name": "SLC25A26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_1241600", "map_id": "PF3D7_1241600", "name": "SLC25A26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691543", "map_id": "none", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_109277", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10691540", "map_id": "none", "name": "Type III Na+/Pi cotransporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IDS7", "map_id": "Q8IDS7", "name": "SLC20A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1340900", "map_id": "PF3D7_1340900", "name": "SLC20A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692626", "map_id": "none", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_742368", "map_id": "CHEBI:17009", "name": "GDP-Fuc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_205683", "map_id": "CHEBI:17009", "name": "GDP-Fuc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10692623", "map_id": "O96200", "name": "SLC35C1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "PF3D7_0212000", "map_id": "PF3D7_0212000", "name": "SLC35C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692613", "map_id": "none", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_727810", "map_id": "CHEBI:17361", "name": "CMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4085435", "map_id": "CHEBI:16556", "name": "CMP-Neu5Ac", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_727815", "map_id": "CHEBI:16556", "name": "CMP-Neu5Ac", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_109395", "map_id": "CHEBI:17361", "name": "CMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10692610", "map_id": "Q8I449", "name": "SLC35A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "PF3D7_0505300", "map_id": "PF3D7_0505300", "name": "SLC35A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692618", "map_id": "none", "name": "SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_735698", "map_id": "CHEBI:16695", "name": "uridine 5'-monophosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_735692", "map_id": "none", "name": "UDP-Gal, UDP-GalNAc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_735700", "map_id": "CHEBI:16650", "name": "UDP-GalNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_735682", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_109402", "map_id": "CHEBI:16695", "name": "UMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_735691", "map_id": "none", "name": "UDP-Gal, UDP-GalNAc", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10692615", "map_id": "Q8I449", "name": "SLC35A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10688817", "map_id": "none", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179737", "map_id": "none", "name": "ligands of SLC28A3 & 29A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17596", "map_id": "CHEBI:17596", "name": "CHEBI:17596", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16750", "map_id": "CHEBI:16750", "name": "CHEBI:16750", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16704", "map_id": "CHEBI:16704", "name": "CHEBI:16704", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17748", "map_id": "CHEBI:17748", "name": "CHEBI:17748", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16335", "map_id": "CHEBI:16335", "name": "CHEBI:16335", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17562", "map_id": "CHEBI:17562", "name": "CHEBI:17562", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_179743", "map_id": "none", "name": "ligands of SLC28A3 & 29A1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688812", "map_id": "none", "name": "SLC29A1-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IDM6", "map_id": "Q8IDM6", "name": "SLC29A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1469400", "map_id": "PF3D7_1469400", "name": "SLC29A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692593", "map_id": "none", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_727782", "map_id": "none", "name": "nucleosides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_5635947", "map_id": "CHEBI:16708", "name": "Ade", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_727746", "map_id": "none", "name": "nucleosides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692590", "map_id": "none", "name": "Homologues of SLC29A3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "Q8IKE3", "map_id": "Q8IKE3", "name": "SLC29A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689584", "map_id": "none", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_113593", "map_id": "CHEBI:30616", "name": "ATP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113581", "map_id": "CHEBI:456216", "name": "ADP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10689581", "map_id": "none", "name": "SLC25A5,6 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q8IJ34", "map_id": "Q8IJ34", "name": "SLC25A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1037300", "map_id": "PF3D7_1037300", "name": "SLC25A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBF2", "map_id": "Q8IBF2", "name": "SLC25A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688810", "map_id": "none", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179742", "map_id": "none", "name": "ligands of SLC29A2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16040", "map_id": "CHEBI:16040", "name": "CHEBI:16040", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16235", "map_id": "CHEBI:16235", "name": "CHEBI:16235", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17821", "map_id": "CHEBI:17821", "name": "CHEBI:17821", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_83962", "map_id": "CHEBI:17568", "name": "Ura", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29850", "map_id": "CHEBI:17368", "name": "Hyp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_179747", "map_id": "none", "name": "ligands of SLC29A2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10688805", "map_id": "none", "name": "SLC29A2-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10688808", "map_id": "none", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10692584", "map_id": "none", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_727774", "map_id": "none", "name": "ligands of SLC29A4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_727737", "map_id": "none", "name": "ligands of SLC29A4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692581", "map_id": "none", "name": "Homologues of SLC29A4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10688815", "map_id": "none", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10692605", "map_id": "none", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10692601", "map_id": "none", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_76183", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_727753", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10692598", "map_id": "Q8IJ40", "name": "SLC33A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "PF3D7_1036800", "map_id": "PF3D7_1036800", "name": "SLC33A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703281", "map_id": "none", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_70115", "map_id": "CHEBI:17925", "name": "Glc", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10689995", "map_id": "none", "name": "GLUT2 / SLC2A2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8I2V8", "map_id": "Q8I2V8", "name": "SLC2A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0919500", "map_id": "PF3D7_0919500", "name": "SLC2A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7KWJ5", "map_id": "Q7KWJ5", "name": "SLC2A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691617", "map_id": "none", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_428819", "map_id": "none", "name": "hexoses transported by GLUT7/11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_29532", "map_id": "CHEBI:15824", "name": "Fru", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_428802", "map_id": "none", "name": "hexoses transported by GLUT7/11", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10691614", "map_id": "none", "name": "GLUT7/11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692151", "map_id": "none", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692147", "map_id": "none", "name": "GLUT1:ATP tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10692145", "map_id": "none", "name": "GLUT1 / SLC2A1 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10696565", "map_id": "none", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10692149", "map_id": "none", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10703268", "map_id": "none", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703265", "map_id": "none", "name": "GLUT3 / SLC2A3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692154", "map_id": "none", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10691626", "map_id": "none", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429078", "map_id": "none", "name": "Fru,Glc,urate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_429148", "map_id": "none", "name": "Fru,Glc,urate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10691623", "map_id": "none", "name": "Homologues of SLC2A9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10703279", "map_id": "none", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703276", "map_id": "none", "name": "GLUT4 / SLC2A4 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10703263", "map_id": "none", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703260", "map_id": "none", "name": "GLUT14 / SLC2A14 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10698311", "map_id": "none", "name": "ACO1 binds 4Fe-4S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5690881", "map_id": "none", "name": "4Fe-4S", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698307", "map_id": "Q8IDR8", "name": "ACO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1342100", "map_id": "PF3D7_1342100", "name": "ACO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698309", "map_id": "none", "name": "ACO1:4Fe-4S", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDR8", "map_id": "Q8IDR8", "name": "ACO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692748", "map_id": "none", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_74722", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10688527", "map_id": "none", "name": "V-ATPase:ATP6AP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "C0H4P0", "map_id": "C0H4P0", "name": "ATP6V0E1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0721900", "map_id": "PF3D7_0721900", "name": "ATP6V0E1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3R7", "map_id": "Q8I3R7", "name": "ATP6V0C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0519200", "map_id": "PF3D7_0519200", "name": "ATP6V0C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAQ8", "map_id": "Q8IAQ8", "name": "ATP6V0A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0806800", "map_id": "PF3D7_0806800", "name": "ATP6V0A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDF7", "map_id": "Q8IDF7", "name": "ATP6V0B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1354400", "map_id": "PF3D7_1354400", "name": "ATP6V0B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKJ0", "map_id": "Q8IKJ0", "name": "ATP6V0D1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1464700", "map_id": "PF3D7_1464700", "name": "ATP6V0D1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2H3", "map_id": "Q8I2H3", "name": "ATP6V1E2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0934500", "map_id": "PF3D7_0934500", "name": "ATP6V1E2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE84", "map_id": "Q8IE84", "name": "ATP6V1G1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1323200", "map_id": "PF3D7_1323200", "name": "ATP6V1G1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q76NM6", "map_id": "Q76NM6", "name": "vapA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF13_0065", "map_id": "PF13_0065", "name": "vapA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHW4", "map_id": "Q8IHW4", "name": "ATP6V1F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1140100", "map_id": "PF3D7_1140100", "name": "ATP6V1F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEP9", "map_id": "Q8IEP9", "name": "ATP6V1H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1306600", "map_id": "PF3D7_1306600", "name": "ATP6V1H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I280", "map_id": "Q8I280", "name": "ATP6V1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0106100", "map_id": "PF3D7_0106100", "name": "ATP6V1C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6ZMA8", "map_id": "Q6ZMA8", "name": "ATP6V1B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0406100", "map_id": "PF3D7_0406100", "name": "ATP6V1B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDS0", "map_id": "Q8IDS0", "name": "ATP6V1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1341900", "map_id": "PF3D7_1341900", "name": "ATP6V1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698318", "map_id": "none", "name": "ACO1:4Fe-4S isomerises CIT to ISCIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76190", "map_id": "CHEBI:30769", "name": "CIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_389545", "map_id": "CHEBI:151", "name": "ISCIT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10698349", "map_id": "none", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698313", "map_id": "Q8IDR8", "name": "IREB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698340", "map_id": "Q8IDR8", "name": "Ub-K-IREB2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698346", "map_id": "none", "name": "SKP1:FBXL5:CUL1:NEDD8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10692878", "map_id": "none", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692873", "map_id": "none", "name": "SMG1:UPF1:EJC:Translated mRNP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A5K1K8X7", "map_id": "A0A5K1K8X7", "name": "NCBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1369500", "map_id": "PF3D7_1369500", "name": "NCBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1T2", "map_id": "Q8I1T2", "name": "NCBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0415500", "map_id": "PF3D7_0415500", "name": "NCBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIC9", "map_id": "Q8IIC9", "name": "GSPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1123400", "map_id": "PF3D7_1123400", "name": "GSPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IFN9", "map_id": "Q8IFN9", "name": "EIF4A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0422700", "map_id": "PF3D7_0422700", "name": "EIF4A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBJ9", "map_id": "Q8IBJ9", "name": "MAGOHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0725200", "map_id": "PF3D7_0725200", "name": "MAGOHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2Q1", "map_id": "Q8I2Q1", "name": "UPF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0925800", "map_id": "PF3D7_0925800", "name": "UPF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE18", "map_id": "Q8IE18", "name": "RNPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1330800", "map_id": "PF3D7_1330800", "name": "RNPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96203", "map_id": "O96203", "name": "ETF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0212300", "map_id": "PF3D7_0212300", "name": "ETF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A143ZY29", "map_id": "A0A143ZY29", "name": "phospho-p-4S-UPF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1005500", "map_id": "PF3D7_1005500", "name": "phospho-p-4S-UPF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692875", "map_id": "none", "name": "SMG1:Phosphorylated UPF1:EJC:Translated mRNP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697478", "map_id": "none", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697474", "map_id": "Q8ILL6", "name": "phospho-p-T68-CHEK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1423600", "map_id": "PF3D7_1423600", "name": "phospho-p-S,3T-CHEK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697476", "map_id": "none", "name": "p-T68-CHEK2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILL6", "map_id": "Q8ILL6", "name": "phospho-p-S,3T-CHEK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697486", "map_id": "none", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697483", "map_id": "Q8ILL6", "name": "phospho-p-S,3T-CHEK2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689771", "map_id": "none", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689766", "map_id": "none", "name": "SCF-beta-TrCP:phospho-Emi1 complexes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJR4", "map_id": "Q8IJR4", "name": "BTRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1410300", "map_id": "PF3D7_1410300", "name": "BTRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILZ2", "map_id": "Q8ILZ2", "name": "BTRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689768", "map_id": "none", "name": "SCF-associated multiubiquitinated Emi1complexes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689762", "map_id": "none", "name": "BTRC:CUL1:SKP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689773", "map_id": "none", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689729", "map_id": "Q8IJD7", "name": "FZR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1026400", "map_id": "PF3D7_1026400", "name": "phospho-p-FZR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10686942", "map_id": "none", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_30187", "map_id": "CHEBI:18077", "name": "dTTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10686458", "map_id": "none", "name": "RNA primer:origin duplex:DNA polymerase alpha:primase complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30185", "map_id": "CHEBI:16311", "name": "dCTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29892", "map_id": "CHEBI:16497", "name": "dGTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29604", "map_id": "CHEBI:16284", "name": "dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686433", "map_id": "none", "name": "DNA polymerase alpha:primase", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10686461", "map_id": "none", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10686456", "map_id": "none", "name": "DNA polymerase alpha:primase:DNA polymerase alpha:origin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IEN4", "map_id": "Q8IEN4", "name": "POLE3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1308100", "map_id": "PF3D7_1308100", "name": "POLE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KTD8", "map_id": "C6KTD8", "name": "POLE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0630300", "map_id": "PF3D7_0630300", "name": "POLE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I579", "map_id": "Q8I579", "name": "POLE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1234300", "map_id": "PF3D7_1234300", "name": "POLE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_30595", "map_id": "none", "name": "NTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110577", "map_id": "CHEBI:17677", "name": "CTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29494", "map_id": "CHEBI:15713", "name": "UTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10686452", "map_id": "none", "name": "DNA polymerase epsilon", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688544", "map_id": "none", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10688540", "map_id": "Q8IC23", "name": "phospho-p-T286-CCND1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10688542", "map_id": "Q8IC23", "name": "phospho-p-T286-CCND1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10688548", "map_id": "none", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688546", "map_id": "none", "name": "multi-ubiquitinated phospho-(T286) Cyclin D1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689779", "map_id": "none", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10689722", "map_id": "none", "name": "CCNA:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689741", "map_id": "none", "name": "CCNA:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689952", "map_id": "none", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689775", "map_id": "Q8IJD7", "name": "FZR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10689777", "map_id": "Q8IJD7", "name": "phospho-p-FZR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689724", "map_id": "none", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687085", "map_id": "none", "name": "Homologues of CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689716", "map_id": "none", "name": "CCNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10696324", "map_id": "none", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_5221122", "map_id": "CHEBI:29089", "name": "1,2-diacyl-glycerol 3-phosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_5221124", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10695746", "map_id": "none", "name": "LPIN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "O77317", "map_id": "O77317", "name": "LPIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0303200", "map_id": "PF3D7_0303200", "name": "LPIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694673", "map_id": "none", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10694648", "map_id": "none", "name": "Nucleosome with H3K4me2/3:H4K20me1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10694615", "map_id": "none", "name": "Condensin II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IED2", "map_id": "Q8IED2", "name": "SMC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MAL13P1.96", "map_id": "MAL13P1.96", "name": "SMC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKZ3", "map_id": "Q8IKZ3", "name": "phospho-p-S-NCAPG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1448200", "map_id": "PF3D7_1448200", "name": "phospho-p-S-NCAPG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I413", "map_id": "Q8I413", "name": "SMC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0509100", "map_id": "PF3D7_0509100", "name": "SMC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96140", "map_id": "O96140", "name": "phospho-p-S-NCAPH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0204000", "map_id": "PF3D7_0204000", "name": "phospho-p-S-NCAPH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8II07", "map_id": "Q8II07", "name": "phospho-p-T1415,S1419-NCAPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1135600", "map_id": "PF3D7_1135600", "name": "phospho-p-T1415,S1419-NCAPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694667", "map_id": "none", "name": "Condensin II:Nucleosome with H4K20me1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10694671", "map_id": "none", "name": "Condensin II:RB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10694709", "map_id": "none", "name": "SETD8 monomethylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10694658", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10694654", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3:H4K20me1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10694661", "map_id": "none", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10694699", "map_id": "none", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10694683", "map_id": "none", "name": "p-T210-PLK1:Phosphorylated Condensin II:Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10694696", "map_id": "none", "name": "Hyperphosphorylated Condensin II:Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10694841", "map_id": "none", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694807", "map_id": "none", "name": "Condensin I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I2Y3", "map_id": "Q8I2Y3", "name": "phospho-p-S-NCAPG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0917000", "map_id": "PF3D7_0917000", "name": "phospho-p-S-NCAPG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H598", "map_id": "C0H598", "name": "phospho-p-S570-NCAPH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1304000", "map_id": "PF3D7_1304000", "name": "phospho-p-S570-NCAPH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6S3H2", "map_id": "C6S3H2", "name": "phospho-p-S-NCAPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1403100", "map_id": "PF3D7_1403100", "name": "phospho-p-S-NCAPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694797", "map_id": "none", "name": "CK2 Phosphorylated Condensin I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10694838", "map_id": "none", "name": "Casein kinase II", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIR9", "map_id": "Q8IIR9", "name": "CSNK2A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1108400", "map_id": "PF3D7_1108400", "name": "CSNK2A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77385", "map_id": "O77385", "name": "CSNK2A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0317200", "map_id": "PF3D7_0317200", "name": "CSNK2A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDR5", "map_id": "Q8IDR5", "name": "CSNK2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1342400", "map_id": "PF3D7_1342400", "name": "CSNK2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694809", "map_id": "none", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2529006", "map_id": "none", "name": "Unknown Phosphatase", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10689490", "map_id": "none", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10687093", "map_id": "none", "name": "CCNE:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10687099", "map_id": "none", "name": "CCNE:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10687095", "map_id": "none", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687091", "map_id": "none", "name": "CCNE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689368", "map_id": "none", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113656", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex with DNA damage", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10686946", "map_id": "none", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_68419", "map_id": "none", "name": "origin of replication", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686454", "map_id": "none", "name": "DNA polymerase epsilon:origin complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10686463", "map_id": "none", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10702067", "map_id": "none", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702063", "map_id": "O77328", "name": "AURKA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0309200", "map_id": "PF3D7_0309200", "name": "PolyUb-AURKA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702058", "map_id": "none", "name": "SKP1:CUL1:RBX1:FBXL7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10702065", "map_id": "none", "name": "SCF-FBXL7:AURKA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77328", "map_id": "O77328", "name": "PolyUb-AURKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702090", "map_id": "none", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702087", "map_id": "none", "name": "SCF-FBXL7:PolyUb-AURKA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702092", "map_id": "none", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10690786", "map_id": "none", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690778", "map_id": "none", "name": "SAR1B:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I1S0", "map_id": "Q8I1S0", "name": "SAR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0416800", "map_id": "PF3D7_0416800", "name": "SAR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690709", "map_id": "none", "name": "SAR1B:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10690783", "map_id": "Q8IIK2", "name": "PREB", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1116400", "map_id": "PF3D7_1116400", "name": "PREB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698657", "map_id": "none", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10690764", "map_id": "none", "name": "COPII cargo:receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8IIP9", "map_id": "Q8IIP9", "name": "GOSR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1111300", "map_id": "PF3D7_1111300", "name": "GOSR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE08", "map_id": "Q8IE08", "name": "STX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1332000", "map_id": "PF3D7_1332000", "name": "STX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H489", "map_id": "C0H489", "name": "SEC24D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0405100", "map_id": "PF3D7_0405100", "name": "SEC24D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IB60", "map_id": "Q8IB60", "name": "pfsec23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0822600", "map_id": "PF3D7_0822600", "name": "pfsec23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2A1", "map_id": "Q8I2A1", "name": "LMAN2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0103900", "map_id": "PF3D7_0103900", "name": "LMAN2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96166", "map_id": "O96166", "name": "(Glc)3(GlcNAc)2(Man)9-CTSC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0207900", "map_id": "PF3D7_0207900", "name": "(Glc)3(GlcNAc)2(Man)9-CTSC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1Y2", "map_id": "Q8I1Y2", "name": "(Glc)3(GlcNAc)2(Man)9-CTSZ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0404700", "map_id": "PF3D7_0404700", "name": "(Glc)3(GlcNAc)2(Man)9-CTSZ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690794", "map_id": "none", "name": "SEC23:SEC24", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H5J6", "map_id": "C0H5J6", "name": "SEC24B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1361100", "map_id": "PF3D7_1361100", "name": "SEC24B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690766", "map_id": "none", "name": "COPII cargo receptors:SAR1B:GTP:SEC23:SEC24", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10698560", "map_id": "none", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10698553", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "C6KT27", "map_id": "C6KT27", "name": "TRAPPC6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0618700", "map_id": "PF3D7_0618700", "name": "TRAPPC6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IM42", "map_id": "Q8IM42", "name": "TRAPPC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1405200", "map_id": "PF3D7_1405200", "name": "TRAPPC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77358", "map_id": "O77358", "name": "TRAPPC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0310700", "map_id": "PF3D7_0310700", "name": "TRAPPC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7KQM2", "map_id": "Q7KQM2", "name": "TRAPPC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0358", "map_id": "PF14_0358", "name": "TRAPPC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE05", "map_id": "Q8IE05", "name": "TRAPPC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1332300", "map_id": "PF3D7_1332300", "name": "TRAPPC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1Q2", "map_id": "Q8I1Q2", "name": "TRAPPC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0418500", "map_id": "PF3D7_0418500", "name": "TRAPPC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBQ3", "map_id": "Q8IBQ3", "name": "TRAPPC9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0719900", "map_id": "PF3D7_0719900", "name": "TRAPPC9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5B3", "map_id": "Q8I5B3", "name": "SEC13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1230700", "map_id": "PF3D7_1230700", "name": "SEC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96221", "map_id": "O96221", "name": "SEC31A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0214100", "map_id": "PF3D7_0214100", "name": "SEC31A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAY0", "map_id": "Q8IAY0", "name": "SEC23IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0814400", "map_id": "PF3D7_0814400", "name": "SEC23IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698557", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "reaction_10701589", "map_id": "none", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10701211", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10701585", "map_id": "O97299", "name": "TBC1D20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "PF3D7_0323100", "map_id": "PF3D7_0323100", "name": "TBC1D20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701587", "map_id": "none", "name": "RAB1:GTP:TBC1D20", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "O97299", "map_id": "O97299", "name": "TBC1D20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698660", "map_id": "none", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10698616", "map_id": "none", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10698612", "map_id": "none", "name": "cis-SNARE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "Q8IJ69", "map_id": "Q8IJ69", "name": "SCFD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1034000", "map_id": "PF3D7_1034000", "name": "SCFD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698614", "map_id": "none", "name": "cis-SNARE:NSF hexamer:3xSNAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10701592", "map_id": "none", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10698448", "map_id": "none", "name": "RAB1:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10698620", "map_id": "none", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10698508", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "species_10698551", "map_id": "none", "name": "TRAPPCII", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694722", "map_id": "none", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10694718", "map_id": "none", "name": "FDXR:FADH2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IHW9", "map_id": "Q8IHW9", "name": "FDXR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1139700", "map_id": "PF3D7_1139700", "name": "FDXR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693606", "map_id": "none", "name": "FDX1,FDX2 (oxidized)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I5R0", "map_id": "Q8I5R0", "name": "FDX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1214600", "map_id": "PF3D7_1214600", "name": "FDX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:33737", "map_id": "CHEBI:33737", "name": "CHEBI:33737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693598", "map_id": "none", "name": "FDX1,FDX2 (reduced)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33738", "map_id": "CHEBI:33738", "name": "CHEBI:33738", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694720", "map_id": "none", "name": "FDXR:FAD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10694724", "map_id": "none", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113600", "map_id": "CHEBI:16474", "name": "NADPH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113563", "map_id": "CHEBI:18009", "name": "NADP+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10695704", "map_id": "none", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695702", "map_id": "none", "name": "SUMO1:K14-UBE2I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10695676", "map_id": "none", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695674", "map_id": "none", "name": "SUMO1:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A5K1K9G1", "map_id": "A0A5K1K9G1", "name": "SUMO1-K35-PIAS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703252", "map_id": "none", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_174602", "map_id": "CHEBI:15904", "name": "LCFAs", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10703249", "map_id": "none", "name": "digestive LIPs", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10688609", "map_id": "none", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_75970", "map_id": "CHEBI:57642", "name": "DHAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73473", "map_id": "CHEBI:57945", "name": "NADH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76114", "map_id": "CHEBI:15978", "name": "G3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29360", "map_id": "CHEBI:57540", "name": "NAD+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688606", "map_id": "none", "name": "GPD1/GPD1L homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIL4", "map_id": "Q8IIL4", "name": "GPD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1114800", "map_id": "PF3D7_1114800", "name": "GPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5P5", "map_id": "Q8I5P5", "name": "GPD1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1216200", "map_id": "PF3D7_1216200", "name": "GPD1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702964", "map_id": "none", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8878649", "map_id": "CHEBI:62833", "name": "MYS-LPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113548", "map_id": "CHEBI:43474", "name": "Pi", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8934414", "map_id": "CHEBI:75562", "name": "1-MMG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10702961", "map_id": "O96171", "name": "ACP6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_0208400", "map_id": "PF3D7_0208400", "name": "ACPP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688574", "map_id": "none", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500604", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1500578", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_426755", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_76194", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688571", "map_id": "none", "name": "AGPAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8I310", "map_id": "Q8I310", "name": "LPCAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0914200", "map_id": "PF3D7_0914200", "name": "LPCAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKZ8", "map_id": "Q8IKZ8", "name": "LPCAT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1447700", "map_id": "PF3D7_1447700", "name": "LPCAT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL28", "map_id": "Q8IL28", "name": "AGPAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1444300", "map_id": "PF3D7_1444300", "name": "AGPAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699324", "map_id": "none", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1602448", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602447", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602366", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10699321", "map_id": "none", "name": "DDHD1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10692323", "map_id": "none", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10692305", "map_id": "none", "name": "Platelet alpha granule contents", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114506", "compartment_display": "platelet alpha granule lumen", "complex": "true" }, { "id": "Q8IBM9", "map_id": "Q8IBM9", "name": "OLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0722400", "map_id": "PF3D7_0722400", "name": "OLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7KQL9", "map_id": "Q7KQL9", "name": "ALDOA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0425", "map_id": "PF14_0425", "name": "ALDOA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I509", "map_id": "Q8I509", "name": "QSOX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1242000", "map_id": "PF3D7_1242000", "name": "QSOX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I563", "map_id": "Q8I563", "name": "VTI1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1448600", "map_id": "PF3D7_1448600", "name": "VTI1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKY7", "map_id": "Q8IKY7", "name": "VTI1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96268", "map_id": "O96268", "name": "SCCPDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0219100", "map_id": "PF3D7_0219100", "name": "SCCPDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692321", "map_id": "none", "name": "Platelet alpha granule contents", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10692394", "map_id": "none", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692370", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I2G8", "map_id": "Q8I2G8", "name": "STXBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0935200", "map_id": "PF3D7_0935200", "name": "STXBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSX9", "map_id": "C6KSX9", "name": "STXBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IFP3", "map_id": "Q8IFP3", "name": "Polyglutamyl-TUBAL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0903700", "map_id": "PF3D7_0903700", "name": "Polyglutamyl-TUBAL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6ZLZ9", "map_id": "Q6ZLZ9", "name": "Polyglutamyl-TUBAL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILW9", "map_id": "Q8ILW9", "name": "POTEKP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1246200", "map_id": "PF3D7_1246200", "name": "POTEKP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4X0", "map_id": "Q8I4X0", "name": "POTEKP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692392", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10692329", "map_id": "none", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10692325", "map_id": "Q8ID33", "name": "CYB5R1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_114510", "compartment_display": "platelet alpha granule membrane", "complex": "false" }, { "id": "PF3D7_1367500", "map_id": "PF3D7_1367500", "name": "CYB5R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692327", "map_id": "Q8ID33", "name": "CYB5R1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10688412", "map_id": "none", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500430", "map_id": "none", "name": "(d)Ura", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16450", "map_id": "CHEBI:16450", "name": "CHEBI:16450", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500244", "map_id": "none", "name": "R1P, dRibP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28542", "map_id": "CHEBI:28542", "name": "CHEBI:28542", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_112016", "map_id": "CHEBI:35425", "name": "R1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688407", "map_id": "none", "name": "UPP1, UPP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3X4", "map_id": "Q8I3X4", "name": "PNP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0513300", "map_id": "PF3D7_0513300", "name": "PNP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703354", "map_id": "none", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9023653", "map_id": "CHEBI:138565", "name": "18(R)-HpEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29450", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9023651", "map_id": "CHEBI:81563", "name": "18(R)-HEPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111745", "map_id": "CHEBI:17858", "name": "GSSG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703349", "map_id": "Q8I5T2", "name": "GPX4-2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1212000", "map_id": "PF3D7_1212000", "name": "GPX8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703352", "map_id": "none", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9020583", "map_id": "CHEBI:138387", "name": "18(S)-HpEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9020474", "map_id": "CHEBI:132801", "name": "18(S)-HEPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10692893", "map_id": "none", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692886", "map_id": "Q8IL78", "name": "K63polyUb-DDX58", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1439100", "map_id": "PF3D7_1439100", "name": "DDX58", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692888", "map_id": "Q8IL78", "name": "DDX58", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692890", "map_id": "O97313", "name": "CYLD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10691191", "map_id": "none", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691189", "map_id": "none", "name": "Potassium voltage-gated channels (beta cell, open)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IKI3", "map_id": "Q8IKI3", "name": "KCNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1465500", "map_id": "PF3D7_1465500", "name": "KCNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5E6", "map_id": "Q8I5E6", "name": "KCNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692412", "map_id": "none", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10692409", "map_id": "none", "name": "GLUT1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10687135", "map_id": "none", "name": "ALDOB tetramer cleaves Fru-1-P to GA and DHAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31221", "map_id": "CHEBI:18105", "name": "Fru 1-P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30393", "map_id": "CHEBI:17378", "name": "GA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687132", "map_id": "none", "name": "ALDOB tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702809", "map_id": "none", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6786250", "map_id": "CHEBI:15727", "name": "CARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8876775", "map_id": "CHEBI:18323", "name": "Anserine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702806", "map_id": "O77329", "name": "CARNMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0309300", "map_id": "PF3D7_0309300", "name": "CARNMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687203", "map_id": "none", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29512", "map_id": "CHEBI:57634", "name": "Fru(6)P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687198", "map_id": "none", "name": "GPI dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILA4", "map_id": "Q8ILA4", "name": "GPI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1436000", "map_id": "PF3D7_1436000", "name": "GPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687522", "map_id": "none", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29362", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113587", "map_id": "CHEBI:30744", "name": "OAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113544", "map_id": "CHEBI:30797", "name": "MAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113526", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687371", "map_id": "none", "name": "MDH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q76NM3", "map_id": "Q76NM3", "name": "MDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1324900", "map_id": "PF3D7_1324900", "name": "MDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687239", "map_id": "none", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29492", "map_id": "CHEBI:58702", "name": "PEP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30485", "map_id": "CHEBI:58289", "name": "2PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687236", "map_id": "none", "name": "enolase dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJN7", "map_id": "Q8IJN7", "name": "ENO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF10_0155", "map_id": "PF10_0155", "name": "ENO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687223", "map_id": "none", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29728", "map_id": "CHEBI:58272", "name": "3PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29800", "map_id": "CHEBI:57604", "name": "1,3BPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687220", "map_id": "none", "name": "PGK complexes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P27362", "map_id": "P27362", "name": "PGK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PFI1105w", "map_id": "PFI1105w", "name": "PGK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687207", "map_id": "none", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29578", "map_id": "CHEBI:59776", "name": "GA3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687178", "map_id": "none", "name": "GAPDH tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IKK7", "map_id": "Q8IKK7", "name": "GAPDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1462800", "map_id": "PF3D7_1462800", "name": "GAPDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687447", "map_id": "none", "name": "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30014", "map_id": "CHEBI:32966", "name": "F1,6PP", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10687205", "map_id": "none", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687188", "map_id": "none", "name": "TPI1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7KQM0", "map_id": "Q7KQM0", "name": "TPI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0378", "map_id": "PF14_0378", "name": "TPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687444", "map_id": "none", "name": "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687441", "map_id": "none", "name": "PGAM dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIG6", "map_id": "Q8IIG6", "name": "BPGM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1120100", "map_id": "PF3D7_1120100", "name": "BPGM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687272", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113552", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113594", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113553", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687257", "map_id": "none", "name": "GOT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O96142", "map_id": "O96142", "name": "PXLP-K279-GOT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0204500", "map_id": "PF3D7_0204500", "name": "PXLP-K279-GOT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689720", "map_id": "none", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10689718", "map_id": "C6KT76", "name": "GCK", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0624000", "map_id": "PF3D7_0624000", "name": "GCK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687154", "map_id": "C6KT76", "name": "GCK", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10687163", "map_id": "none", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687160", "map_id": "none", "name": "glucokinase and hexokinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KT76", "map_id": "C6KT76", "name": "GCK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687480", "map_id": "none", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29398", "map_id": "CHEBI:15361", "name": "PYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687477", "map_id": "none", "name": "pyruvate kinase tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJ37", "map_id": "Q8IJ37", "name": "PKLR-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1037100", "map_id": "PF3D7_1037100", "name": "PKLR-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KTA4", "map_id": "C6KTA4", "name": "PKLR-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703214", "map_id": "none", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8955759", "map_id": "CHEBI:18148", "name": "G1,6BP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687120", "map_id": "none", "name": "PGM2L1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10699884", "map_id": "none", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6798337", "map_id": "CHEBI:19324", "name": "2,3BPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699881", "map_id": "none", "name": "BPGM dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688330", "map_id": "none", "name": "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688318", "map_id": "C0H561", "name": "2xHC-TXN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0925500", "map_id": "PF3D7_0925500", "name": "2xHC-TXN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688320", "map_id": "C0H561", "name": "TXN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688327", "map_id": "none", "name": "TNXRD1:FAD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P61076", "map_id": "P61076", "name": "trxr2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PFI1170c", "map_id": "PFI1170c", "name": "trxr2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687149", "map_id": "none", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31467", "map_id": "CHEBI:16938", "name": "D-Glucono-1,5-lactone 6-phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687146", "map_id": "none", "name": "G6PD dimer and tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IKU0", "map_id": "Q8IKU0", "name": "G6PD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0511", "map_id": "PF14_0511", "name": "G6PD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703102", "map_id": "none", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10703094", "map_id": "none", "name": "SCUBE1,SCUBE3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "C0H518", "map_id": "C0H518", "name": "SCUBE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1208200", "map_id": "PF3D7_1208200", "name": "SCUBE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K8N7", "map_id": "A0A5K1K8N7", "name": "SCUBE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703100", "map_id": "none", "name": "SCUBE1,SCUBE3 polymer, SCUBE3 polymer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10698562", "map_id": "none", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10690729", "map_id": "Q8IB60", "name": "pfsec23", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690727", "map_id": "none", "name": "SEC24C,D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10690721", "map_id": "none", "name": "GOSR2,STX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10690731", "map_id": "none", "name": "SEC23A:SEC24C,D:GOSR2,STX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10698618", "map_id": "none", "name": "LMAN family proteins bind glycosylated cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10690760", "map_id": "none", "name": "glycosylated LMAN cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10690746", "map_id": "none", "name": "LMAN family receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10690762", "map_id": "none", "name": "LMAN receptor:glycosylated cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10698568", "map_id": "none", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10690665", "map_id": "O97323", "name": "SEC22B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10698564", "map_id": "none", "name": "SEC24A,SEC24B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10698566", "map_id": "none", "name": "SEC24A,B:SEC23A:SEC22B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10694553", "map_id": "none", "name": "EET(1) is hydrolysed to DHET(1) by EPHX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2161818", "map_id": "none", "name": "EET(1)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:34450", "map_id": "CHEBI:34450", "name": "CHEBI:34450", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34130", "map_id": "CHEBI:34130", "name": "CHEBI:34130", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34490", "map_id": "CHEBI:34490", "name": "CHEBI:34490", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34157", "map_id": "CHEBI:34157", "name": "CHEBI:34157", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2161883", "map_id": "none", "name": "DHET(1)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:63974", "map_id": "CHEBI:63974", "name": "CHEBI:63974", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63969", "map_id": "CHEBI:63969", "name": "CHEBI:63969", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63970", "map_id": "CHEBI:63970", "name": "CHEBI:63970", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63966", "map_id": "CHEBI:63966", "name": "CHEBI:63966", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694550", "map_id": "none", "name": "EPHX2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IM75", "map_id": "Q8IM75", "name": "EPHX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1401300", "map_id": "PF3D7_1401300", "name": "EPHX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703339", "map_id": "none", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_1614595", "map_id": "CHEBI:16094", "name": "S2O3(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013199", "map_id": "CHEBI:18407", "name": "HCN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013207", "map_id": "CHEBI:17359", "name": "SO3(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013191", "map_id": "CHEBI:29200", "name": "HSCN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10703333", "map_id": "Q8I5Y1", "name": "MPST", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1206400", "map_id": "PF3D7_1206400", "name": "CysS248-MPST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703402", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9012592", "map_id": "CHEBI:16208", "name": "3MPYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10703400", "map_id": "Q8I5Y1", "name": "CysS248-MPST", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113557", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10703336", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9012724", "map_id": "CHEBI:17137", "name": "HSO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10703343", "map_id": "none", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013543", "map_id": "none", "name": "sulfanegen", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10703341", "map_id": "none", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10703132", "map_id": "none", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698286", "map_id": "Q8IEI4", "name": "NEDD8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698177", "map_id": "Q8IKM8", "name": "UCHL3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10692793", "map_id": "none", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692761", "map_id": "A0A143ZY29", "name": "UPF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692789", "map_id": "none", "name": "Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692791", "map_id": "none", "name": "UPF1:eRF3 Complex on Translated mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10690540", "map_id": "none", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690537", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_29870", "map_id": "CHEBI:15372", "name": "BH4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q8I0V4", "map_id": "Q8I0V4", "name": "HSP90AA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1443900", "map_id": "PF3D7_1443900", "name": "HSP90AA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL32", "map_id": "Q8IL32", "name": "HSP90AA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IC05", "map_id": "Q8IC05", "name": "HSP90AA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5693375", "map_id": "CHEBI:25682", "name": "ADMA", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10692468", "map_id": "none", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29602", "map_id": "CHEBI:17202", "name": "IMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692465", "map_id": "none", "name": "GMPR tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I2U5", "map_id": "Q8I2U5", "name": "GMPR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0920800", "map_id": "PF3D7_0920800", "name": "GMPR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688719", "map_id": "none", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688716", "map_id": "none", "name": "AMPD tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IE53", "map_id": "Q8IE53", "name": "AMPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1329400", "map_id": "PF3D7_1329400", "name": "AMPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688380", "map_id": "none", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73566", "map_id": "CHEBI:17111", "name": "PRPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_500259", "map_id": "none", "name": "Gua, Hyp", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500260", "map_id": "none", "name": "GMP, IMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688377", "map_id": "none", "name": "HGPRT tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJS1", "map_id": "Q8IJS1", "name": "HPRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1012400", "map_id": "PF3D7_1012400", "name": "HPRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688396", "map_id": "none", "name": "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH4+ (ADA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500173", "map_id": "none", "name": "Ade-Rib, dA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17256", "map_id": "CHEBI:17256", "name": "CHEBI:17256", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500172", "map_id": "none", "name": "Ino, dI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28997", "map_id": "CHEBI:28997", "name": "CHEBI:28997", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688393", "map_id": "Q8IJA9", "name": "ADA", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1029600", "map_id": "PF3D7_1029600", "name": "ADA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702565", "map_id": "none", "name": "FarC-PTP4A2 binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702559", "map_id": "Q8IIN1", "name": "FarC-PTP4A2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1113100", "map_id": "PF3D7_1113100", "name": "FarC-PTP4A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702561", "map_id": "C6KSM5", "name": "RABGGTB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0602500", "map_id": "PF3D7_0602500", "name": "RABGGTB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702563", "map_id": "none", "name": "FarC-PTP4A2:RABGGTB", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KSM5", "map_id": "C6KSM5", "name": "RABGGTB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIN1", "map_id": "Q8IIN1", "name": "FarC-PTP4A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702571", "map_id": "none", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702567", "map_id": "Q8IL46", "name": "RABGGTA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1442500", "map_id": "PF3D7_1442500", "name": "RABGGTA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702569", "map_id": "none", "name": "RABGGTA:RABGGTB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IL46", "map_id": "Q8IL46", "name": "RABGGTA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688826", "map_id": "none", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_179838", "map_id": "CHEBI:16618", "name": "PI(3,4,5)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10688822", "map_id": "Q8IIE7", "name": "PDPK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_1121900", "map_id": "PF3D7_1121900", "name": "PDPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688824", "map_id": "none", "name": "PDPK1:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IIE7", "map_id": "Q8IIE7", "name": "PDPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701191", "map_id": "none", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807473", "map_id": "CHEBI:64085", "name": "R-NADPHX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6807477", "map_id": "CHEBI:64084", "name": "S-NADPHX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10701188", "map_id": "none", "name": "APOA1BP dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IKN4", "map_id": "Q8IKN4", "name": "APOA1BP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0570", "map_id": "PF14_0570", "name": "APOA1BP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690276", "map_id": "none", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197230", "map_id": "CHEBI:15940", "name": "NCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_197220", "map_id": "CHEBI:15763", "name": "NAMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690273", "map_id": "none", "name": "NAPRT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KTC6", "map_id": "C6KTC6", "name": "NAPRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0629100", "map_id": "PF3D7_0629100", "name": "NAPRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702553", "map_id": "none", "name": "SLC22A13 transports NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_8869604", "map_id": "CHEBI:32544", "name": "NCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10701199", "map_id": "none", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10701196", "map_id": "Q8IHS6", "name": "CARKD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1143900", "map_id": "PF3D7_1143900", "name": "CARKD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703211", "map_id": "none", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10703208", "map_id": "none", "name": "NADK2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I319", "map_id": "Q8I319", "name": "NADK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0913300", "map_id": "PF3D7_0913300", "name": "NADK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690286", "map_id": "none", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197256", "map_id": "CHEBI:18304", "name": "NAAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29404", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690283", "map_id": "none", "name": "NADSYN1 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I2P2", "map_id": "Q8I2P2", "name": "NADSYN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0926700", "map_id": "PF3D7_0926700", "name": "NADSYN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690218", "map_id": "none", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196095", "map_id": "CHEBI:17998", "name": "ISCAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196066", "map_id": "CHEBI:63910", "name": "MePeOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10703665", "map_id": "none", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193057", "map_id": "CHEBI:17347", "name": "TEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_469662", "map_id": "CHEBI:16330", "name": "DHTEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10695751", "map_id": "C6S3J5", "name": "SRD5A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1455900", "map_id": "PF3D7_1455900", "name": "SRD5A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698686", "map_id": "none", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696835", "map_id": "CHEBI:16469", "name": "EST17b", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5696848", "map_id": "CHEBI:17263", "name": "E1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10698683", "map_id": "Q8IM05", "name": "AKR1B15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10696894", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696890", "map_id": "none", "name": "ARF4:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10690962", "map_id": "Q8IL42", "name": "GBF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10690946", "map_id": "none", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690943", "map_id": "Q8IJ77", "name": "ADC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1033100", "map_id": "PF3D7_1033100", "name": "ADC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10686402", "map_id": "none", "name": "Orc1 associates with Orc4:Orc5:Orc3:Orc2:origin complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10686398", "map_id": "Q8I615", "name": "orc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10686393", "map_id": "none", "name": "Orc4:Orc5:Orc3:Orc2:origin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10686400", "map_id": "none", "name": "Orc1:Orc4:Orc5:Orc3:Orc2:origin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10686409", "map_id": "none", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10692172", "map_id": "none", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692164", "map_id": "none", "name": "p-S189,T193-MAP2K3, p-S207,T211-MAP2K6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IBK6", "map_id": "Q8IBK6", "name": "phospho-p-S207,T211-MAP2K6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692170", "map_id": "none", "name": "p-S189,T193-MAP2K3, p-S207,T211-MAP2K6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10693514", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693510", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_927893", "compartment_display": "endoplasmic reticulum quality control compartment", "complex": "true" }, { "id": "species_10693512", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:60627", "map_id": "CHEBI:60627", "name": "CHEBI:60627", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60628", "map_id": "CHEBI:60628", "name": "CHEBI:60628", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59092", "map_id": "CHEBI:59092", "name": "CHEBI:59092", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60629", "map_id": "CHEBI:60629", "name": "CHEBI:60629", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59087", "map_id": "CHEBI:59087", "name": "CHEBI:59087", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694711", "map_id": "none", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690558", "map_id": "Q8IIE7", "name": "PDPK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693565", "map_id": "none", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1250243", "map_id": "CHEBI:26523", "name": "ROS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10700704", "map_id": "none", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799351", "compartment_display": "specific granule membrane" }, { "id": "species_10700690", "map_id": "none", "name": "Specific granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799351", "compartment_display": "specific granule membrane", "complex": "true" }, { "id": "Q8II31", "map_id": "Q8II31", "name": "TMEM30A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1133300", "map_id": "PF3D7_1133300", "name": "TMEM30A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJB1", "map_id": "Q8IJB1", "name": "TMEM30A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97295", "map_id": "O97295", "name": "DGAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0322300", "map_id": "PF3D7_0322300", "name": "DGAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H5C6", "map_id": "C0H5C6", "name": "SNAP29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1320500", "map_id": "PF3D7_1320500", "name": "SNAP29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDL8", "map_id": "Q8IDL8", "name": "RAB33A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1348100", "map_id": "PF3D7_1348100", "name": "RAB33A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEK4", "map_id": "Q8IEK4", "name": "AP1M1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1311400", "map_id": "PF3D7_1311400", "name": "AP1M1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4T2", "map_id": "Q8I4T2", "name": "TMEM63A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1250200", "map_id": "PF3D7_1250200", "name": "TMEM63A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4U9", "map_id": "Q8I4U9", "name": "TMBIM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1248500", "map_id": "PF3D7_1248500", "name": "TMBIM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700702", "map_id": "none", "name": "Specific granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10700208", "map_id": "none", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane" }, { "id": "species_10700192", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane", "complex": "true" }, { "id": "Q8I3M7", "map_id": "Q8I3M7", "name": "SLC11A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5R9", "map_id": "Q8I5R9", "name": "DYNLL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1357300", "map_id": "PF3D7_1357300", "name": "DYNLL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBG2", "map_id": "Q8IBG2", "name": "DYNLL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDD2", "map_id": "Q8IDD2", "name": "DYNLL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700206", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10700629", "map_id": "none", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen" }, { "id": "species_10700591", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen", "complex": "true" }, { "id": "O96220", "map_id": "O96220", "name": "CCT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0214000", "map_id": "PF3D7_0214000", "name": "CCT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7KQL5", "map_id": "Q7KQL5", "name": "Polyglutamyl-TUBB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF10_0084", "map_id": "PF10_0084", "name": "Polyglutamyl-TUBB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KT34", "map_id": "C6KT34", "name": "Me3K315-VCP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0619400", "map_id": "PF3D7_0619400", "name": "Me3K315-VCP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSW6", "map_id": "C6KSW6", "name": "STK11IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0822500", "map_id": "PF3D7_0822500", "name": "STK11IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I412", "map_id": "Q8I412", "name": "STK11IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IB59", "map_id": "Q8IB59", "name": "STK11IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAM2", "map_id": "Q8IAM2", "name": "PRDX6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0802200", "map_id": "PF3D7_0802200", "name": "PRDX6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1V9", "map_id": "Q8I1V9", "name": "ACTR10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0409900", "map_id": "PF3D7_0409900", "name": "ACTR10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I384", "map_id": "Q8I384", "name": "ARG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0906500", "map_id": "PF3D7_0906500", "name": "ARG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ID33", "map_id": "Q8ID33", "name": "CYB5R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILI2", "map_id": "Q8ILI2", "name": "PA2G4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1428300", "map_id": "PF3D7_1428300", "name": "PA2G4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IM55", "map_id": "Q8IM55", "name": "CPPED1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1403900", "map_id": "PF3D7_1403900", "name": "CPPED1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I501", "map_id": "Q8I501", "name": "GDI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1242800", "map_id": "PF3D7_1242800", "name": "GDI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97247", "map_id": "O97247", "name": "CCT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0306800", "map_id": "PF3D7_0306800", "name": "CCT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2H1", "map_id": "Q8I2H1", "name": "FAF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0934700", "map_id": "PF3D7_0934700", "name": "FAF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700627", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10700075", "map_id": "none", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10700049", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "C6KT12", "map_id": "C6KT12", "name": "AP2A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1246300", "map_id": "PF3D7_1246300", "name": "AP2A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7K6B0", "map_id": "Q7K6B0", "name": "RAB18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0807300", "map_id": "PF3D7_0807300", "name": "RAB18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q76NM7", "map_id": "Q76NM7", "name": "RAB24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1310600", "map_id": "PF3D7_1310600", "name": "RAB24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I274", "map_id": "Q8I274", "name": "GGC-RAB5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0211200", "map_id": "PF3D7_0211200", "name": "GGC-RAB5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H516", "map_id": "C0H516", "name": "RAB7B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0903200", "map_id": "PF3D7_0903200", "name": "RAB7B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHR8", "map_id": "Q8IHR8", "name": "RAB6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1144900", "map_id": "PF3D7_1144900", "name": "RAB6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4M1", "map_id": "C0H4M1", "name": "ATAD3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0707400", "map_id": "PF3D7_0707400", "name": "ATAD3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I385", "map_id": "Q8I385", "name": "DYNC1LI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0906400", "map_id": "PF3D7_0906400", "name": "DYNC1LI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700073", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10700489", "map_id": "none", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen" }, { "id": "species_10700371", "map_id": "none", "name": "Secretory granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "true" }, { "id": "C0H568", "map_id": "C0H568", "name": "DYNLT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0927500", "map_id": "PF3D7_0927500", "name": "DYNLT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBH5", "map_id": "Q8IBH5", "name": "ACTR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1110700", "map_id": "PF3D7_1110700", "name": "ACTR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A143ZXR3", "map_id": "A0A143ZXR3", "name": "ACTR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2A2", "map_id": "Q8I2A2", "name": "ACTR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I0P6", "map_id": "Q8I0P6", "name": "Me3K318-EEF1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1357000", "map_id": "PF3D7_1357000", "name": "Me3K318-EEF1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IB94", "map_id": "Q8IB94", "name": "HUWE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0826100", "map_id": "PF3D7_0826100", "name": "HUWE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIA3", "map_id": "Q8IIA3", "name": "ATG7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1126100", "map_id": "PF3D7_1126100", "name": "ATG7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAU1", "map_id": "Q8IAU1", "name": "DDX3X", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0810600", "map_id": "PF3D7_0810600", "name": "DDX3X", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IB24", "map_id": "Q8IB24", "name": "HSPA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0818900", "map_id": "PF3D7_0818900", "name": "HSPA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I0V1", "map_id": "Q8I0V1", "name": "CTSS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1247800", "map_id": "PF3D7_1247800", "name": "CTSS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I6U5", "map_id": "Q8I6U5", "name": "CTSS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I6U4", "map_id": "Q8I6U4", "name": "CTSS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIL0", "map_id": "Q8IIL0", "name": "CTSS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I613", "map_id": "Q8I613", "name": "SRP14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1203200", "map_id": "PF3D7_1203200", "name": "SRP14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KT01", "map_id": "C6KT01", "name": "PDXK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0616000", "map_id": "PF3D7_0616000", "name": "PDXK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ID43", "map_id": "Q8ID43", "name": "NME2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1366500", "map_id": "PF3D7_1366500", "name": "NME2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5C5", "map_id": "Q8I5C5", "name": "MIF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1229400", "map_id": "PF3D7_1229400", "name": "MIF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5Q4", "map_id": "Q8I5Q4", "name": "PPIE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1215200", "map_id": "PF3D7_1215200", "name": "PPIE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I621", "map_id": "Q8I621", "name": "PPIE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q76NN7", "map_id": "Q76NN7", "name": "PPIE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIK8", "map_id": "Q8IIK8", "name": "PPIE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700487", "map_id": "none", "name": "Secretory granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10700520", "map_id": "none", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen" }, { "id": "species_10700508", "map_id": "none", "name": "Specific granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen", "complex": "true" }, { "id": "Q8IAY9", "map_id": "Q8IAY9", "name": "KPNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0815200", "map_id": "PF3D7_0815200", "name": "KPNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I6Z5", "map_id": "Q8I6Z5", "name": "CTSD(65-412)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1323500", "map_id": "PF3D7_1323500", "name": "CTSD(65-412)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I486", "map_id": "Q8I486", "name": "PI3(23-117)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0501400", "map_id": "PF3D7_0501400", "name": "PI3(23-117)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700518", "map_id": "none", "name": "Specific granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10700136", "map_id": "none", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen" }, { "id": "species_10700108", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen", "complex": "true" }, { "id": "Q8I2Q2", "map_id": "Q8I2Q2", "name": "YPEL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0925600", "map_id": "PF3D7_0925600", "name": "YPEL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700134", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10700943", "map_id": "none", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10700933", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800405", "compartment_display": "ficolin-1-rich granule lumen", "complex": "true" }, { "id": "O97289", "map_id": "O97289", "name": "APEH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0321500", "map_id": "PF3D7_0321500", "name": "APEH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIJ9", "map_id": "Q8IIJ9", "name": "CTSB(80-333)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF11_0174", "map_id": "PF11_0174", "name": "CTSB(80-333)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700941", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10699997", "map_id": "none", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane" }, { "id": "species_10699963", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane", "complex": "true" }, { "id": "Q8IL71", "map_id": "Q8IL71", "name": "VAPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1439800", "map_id": "PF3D7_1439800", "name": "VAPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2V7", "map_id": "Q8I2V7", "name": "DDOST", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0919600", "map_id": "PF3D7_0919600", "name": "DDOST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "B9ZSI6", "map_id": "B9ZSI6", "name": "MAGT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96171", "map_id": "O96171", "name": "ACPP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96193", "map_id": "O96193", "name": "GGC-RAB5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3F8", "map_id": "Q8I3F8", "name": "SURF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0531000", "map_id": "PF3D7_0531000", "name": "SURF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10699995", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10700781", "map_id": "none", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800424", "compartment_display": "ficolin-1-rich granule membrane" }, { "id": "species_10700769", "map_id": "none", "name": "Ficolin-rich granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800424", "compartment_display": "ficolin-1-rich granule membrane", "complex": "true" }, { "id": "Q8IIL9", "map_id": "Q8IIL9", "name": "TBC1D2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1114200", "map_id": "PF3D7_1114200", "name": "TBC1D2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I379", "map_id": "Q8I379", "name": "TBC1D2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10700779", "map_id": "none", "name": "Ficolin-rich granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10701410", "map_id": "none", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_6803081", "map_id": "CHEBI:16412", "name": "LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222574", "compartment_display": "cell wall", "complex": "false" }, { "id": "species_10701406", "map_id": "none", "name": "PI3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10701408", "map_id": "none", "name": "PI3:LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_166005", "map_id": "CHEBI:16412", "name": "LPS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10701031", "map_id": "none", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_181015", "map_id": "CHEBI:28640", "name": "Lipoteichoic acid", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10701027", "map_id": "Q8I616", "name": "HC23,45-HMGB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10701029", "map_id": "none", "name": "HC23,45-HMGB1:LTA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10701035", "map_id": "none", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10701033", "map_id": "none", "name": "HC23,45-HMGB1:LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10701162", "map_id": "none", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10690933", "map_id": "Q8I616", "name": "HMGB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10703347", "map_id": "none", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694974", "map_id": "A0A5K1K8X8", "name": "DDX41", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0527900", "map_id": "PF3D7_0527900", "name": "DDX41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8982080", "map_id": "none", "name": "c-di-AMP, c-di-GMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:49537", "map_id": "CHEBI:49537", "name": "CHEBI:49537", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:47037", "map_id": "CHEBI:47037", "name": "CHEBI:47037", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703345", "map_id": "none", "name": "DDX41:c-di-AMP, c-di-GMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A5K1K8X8", "map_id": "A0A5K1K8X8", "name": "DDX41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694983", "map_id": "none", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3134861", "map_id": "none", "name": "Unmethylated CpG DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694979", "map_id": "O77360", "name": "DHX36", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0310500", "map_id": "PF3D7_0310500", "name": "DHX36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694981", "map_id": "none", "name": "DHX36:CpG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77360", "map_id": "O77360", "name": "DHX36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690562", "map_id": "none", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202277", "map_id": "none", "name": "PIP3, PI(3,4)P2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_202247", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10690560", "map_id": "none", "name": "PDK1:PIP2,PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10693549", "map_id": "none", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_10693546", "map_id": "none", "name": "V-ATPase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10688366", "map_id": "none", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111584", "map_id": "CHEBI:15652", "name": "XMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688363", "map_id": "Q8IJR9", "name": "GMPS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1012600", "map_id": "PF3D7_1012600", "name": "GMPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689181", "map_id": "none", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29448", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_35141", "map_id": "CHEBI:15919", "name": "ADS", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689178", "map_id": "none", "name": "ADSS, ADSSL1 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDF6", "map_id": "Q8IDF6", "name": "Adss", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF13_0287", "map_id": "PF13_0287", "name": "Adss", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698331", "map_id": "none", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10698328", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30555", "map_id": "CHEBI:16516", "name": "dNTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10698326", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10690535", "map_id": "none", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690512", "map_id": "none", "name": "eNOS:CaM:HSP90:p-AKT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10690533", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10693927", "map_id": "none", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10689795", "map_id": "none", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174390", "map_id": "CHEBI:57844", "name": "L-Met", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689792", "map_id": "none", "name": "MAT1A multimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7K6A4", "map_id": "Q7K6A4", "name": "MAT1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0922200", "map_id": "PF3D7_0922200", "name": "MAT1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689813", "map_id": "none", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_175977", "map_id": "CHEBI:36062", "name": "3,4DHBNZ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_175978", "map_id": "CHEBI:63797", "name": "3H,4MBNZ", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689810", "map_id": "Q8IKF4", "name": "COMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10700735", "map_id": "none", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6806829", "map_id": "CHEBI:17826", "name": "MMAIII", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6800127", "map_id": "CHEBI:48765", "name": "DMAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10700729", "map_id": "none", "name": "N6AMT1:TRMT112", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IET4", "map_id": "Q8IET4", "name": "N6AMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1303100", "map_id": "PF3D7_1303100", "name": "N6AMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IM19", "map_id": "Q8IM19", "name": "TRMT112", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1407500", "map_id": "PF3D7_1407500", "name": "TRMT112", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698363", "map_id": "none", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692212", "map_id": "CHEBI:81626", "name": "BaPtDHD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692216", "map_id": "CHEBI:87752", "name": "BaP-7,8-dione", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10697185", "map_id": "Q8IM05", "name": "AKR1A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10689805", "map_id": "none", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174393", "map_id": "CHEBI:17515", "name": "gGluCys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689802", "map_id": "none", "name": "GSS:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3Y4", "map_id": "Q8I3Y4", "name": "GSS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0512200", "map_id": "PF3D7_0512200", "name": "GSS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689823", "map_id": "none", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176070", "map_id": "none", "name": "Electrophilic substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:29132", "map_id": "CHEBI:29132", "name": "CHEBI:29132", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34718", "map_id": "CHEBI:34718", "name": "CHEBI:34718", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:30614", "map_id": "CHEBI:30614", "name": "CHEBI:30614", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_176049", "map_id": "none", "name": "electrophilic substrate:SG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:8927", "map_id": "CHEBI:8927", "name": "CHEBI:8927", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:32639", "map_id": "CHEBI:32639", "name": "CHEBI:32639", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34479", "map_id": "CHEBI:34479", "name": "CHEBI:34479", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689820", "map_id": "none", "name": "HPGDS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILQ7", "map_id": "Q8ILQ7", "name": "GST", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF14_0187", "map_id": "PF14_0187", "name": "GST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687505", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29416", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687502", "map_id": "C6KTB4", "name": "ACSS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0627800", "map_id": "PF3D7_0627800", "name": "ACSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692132", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113539", "map_id": "CHEBI:30089", "name": "CH3COO-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159448", "map_id": "CHEBI:16027", "name": "adenosine 5'-monophosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113559", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10692129", "map_id": "C6KTB4", "name": "ACSS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10689254", "map_id": "none", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689245", "map_id": "none", "name": "p-T200-CAMK4:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10689251", "map_id": "none", "name": "p-S12.S13,T200-CAMK4:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10691885", "map_id": "none", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691877", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IL57", "map_id": "Q8IL57", "name": "phospho-p-CAMKK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1441300", "map_id": "PF3D7_1441300", "name": "phospho-p-CAMKK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10691882", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10699811", "map_id": "none", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10699781", "map_id": "none", "name": "18SE pre-40S particle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I1N8", "map_id": "Q8I1N8", "name": "RIOK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0420100", "map_id": "PF3D7_0420100", "name": "RIOK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKE4", "map_id": "Q8IKE4", "name": "PNO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1469300", "map_id": "PF3D7_1469300", "name": "PNO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1Q0", "map_id": "Q8I1Q0", "name": "NOB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0418700", "map_id": "PF3D7_0418700", "name": "NOB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96224", "map_id": "O96224", "name": "LTV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0214400", "map_id": "PF3D7_0214400", "name": "LTV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KT53", "map_id": "C6KT53", "name": "RPP30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0621500", "map_id": "PF3D7_0621500", "name": "RPP30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDN4", "map_id": "Q8IDN4", "name": "RPP25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1346300", "map_id": "PF3D7_1346300", "name": "RPP25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAX8", "map_id": "Q8IAX8", "name": "RPP25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIR2", "map_id": "Q8IIR2", "name": "BYSL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1109400", "map_id": "PF3D7_1109400", "name": "BYSL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE34", "map_id": "Q8IE34", "name": "RPP21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1327200", "map_id": "PF3D7_1327200", "name": "RPP21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHZ9", "map_id": "Q8IHZ9", "name": "CK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1136500.1", "map_id": "PF3D7_1136500.1", "name": "CK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6S3F7", "map_id": "C6S3F7", "name": "CSNK1E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1136500.2", "map_id": "PF3D7_1136500.2", "name": "CSNK1E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A2N6", "map_id": "A0A144A2N6", "name": "RIOK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1230900", "map_id": "PF3D7_1230900", "name": "RIOK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKV7", "map_id": "Q8IKV7", "name": "TSR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1451900", "map_id": "PF3D7_1451900", "name": "TSR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10699783", "map_id": "A0A144A2N6", "name": "RIOK3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699789", "map_id": "Q8I1Q0", "name": "NOB1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699791", "map_id": "Q8IKE4", "name": "PNO1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699785", "map_id": "Q8IIR2", "name": "BYSL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699803", "map_id": "none", "name": "Homologues of CSNK1E", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10699787", "map_id": "O96224", "name": "LTV1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699797", "map_id": "A0A144A2N6", "name": "RIOK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687798", "map_id": "none", "name": "40S ribosomal complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10699793", "map_id": "Q8I1N8", "name": "RIOK2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691650", "map_id": "none", "name": "Homologues of CSNK1G2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10699795", "map_id": "Q8IKV7", "name": "TSR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699809", "map_id": "C0H4F7", "name": "WBSCR22", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0522300", "map_id": "PF3D7_0522300", "name": "WBSCR22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697067", "map_id": "none", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_964746", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10697064", "map_id": "none", "name": "SLC2A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10694064", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806199", "map_id": "CHEBI:16749", "name": "PI", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_1806200", "map_id": "CHEBI:17283", "name": "PI3P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10694061", "map_id": "none", "name": "PIK3C3:Mn2+:PIK3R4:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10701695", "map_id": "none", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8849959", "map_id": "none", "name": "PI(4,5)P2, PI(3,4)P2, PI(3,4,5)P3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_179856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_8849958", "map_id": "none", "name": "PI5P, PI3P, PI(3,5)P2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_1806224", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1806240", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10701692", "map_id": "Q8IDF9", "name": "INPP5F", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "PF3D7_1354200", "map_id": "PF3D7_1354200", "name": "INPP5F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694096", "map_id": "none", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_392417", "map_id": "CHEBI:17526", "name": "PI4P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10693987", "map_id": "none", "name": "PIP5K1A-C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694013", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694010", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688787", "map_id": "none", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688783", "map_id": "Q8I2N3", "name": "SLBP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0927600", "map_id": "PF3D7_0927600", "name": "SLBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688778", "map_id": "none", "name": "Capped Intronless Histone pre-mRNA:CBC complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10688785", "map_id": "none", "name": "Capped Intronless Histone pre-mRNA:CBP80:CBP20:SLBP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I2N3", "map_id": "Q8I2N3", "name": "SLBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689594", "map_id": "none", "name": "OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10689591", "map_id": "Q8I611", "name": "SLC22A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10688242", "map_id": "none", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687916", "map_id": "none", "name": "48S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10687864", "map_id": "Q8IHT2", "name": "EIF1AX", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_72617", "map_id": "none", "name": "eIF1", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687921", "map_id": "Q8I5X8", "name": "EIF5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1206700", "map_id": "PF3D7_1206700", "name": "EIF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687927", "map_id": "none", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10688234", "map_id": "none", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688215", "map_id": "none", "name": "80S ribosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688238", "map_id": "none", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687859", "map_id": "none", "name": "eIF3 subunits complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688236", "map_id": "none", "name": "40S:eIF3:eIF1A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10687937", "map_id": "none", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687883", "map_id": "none", "name": "eIF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_72393", "map_id": "none", "name": "Met-tRNAi", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687885", "map_id": "none", "name": "ternary complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688240", "map_id": "none", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687887", "map_id": "none", "name": "43S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10687935", "map_id": "none", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10687929", "map_id": "none", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687903", "map_id": "O97266", "name": "EIF4E", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687898", "map_id": "none", "name": "eIF4A subunits complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10687908", "map_id": "Q8IIS9", "name": "EIF4G1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687910", "map_id": "none", "name": "eIF4F", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688230", "map_id": "none", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688224", "map_id": "none", "name": "80S:Met-tRNAi:mRNA:eIF5B:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KSR8", "map_id": "C6KSR8", "name": "EIF5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0607000", "map_id": "PF3D7_0607000", "name": "EIF5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688228", "map_id": "none", "name": "80S:Met-tRNAi:mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688226", "map_id": "none", "name": "eIF5B:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688232", "map_id": "none", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688222", "map_id": "none", "name": "eIF5B:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10687923", "map_id": "none", "name": "40S:Met-tRNAi:mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10687968", "map_id": "none", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687964", "map_id": "none", "name": "eIF2B subunits complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJQ6", "map_id": "Q8IJQ6", "name": "EIF2B4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1013900", "map_id": "PF3D7_1013900", "name": "EIF2B4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBB6", "map_id": "Q8IBB6", "name": "EIF2B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0828500", "map_id": "PF3D7_0828500", "name": "EIF2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A0U7", "map_id": "A0A144A0U7", "name": "EIF2B5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1213900", "map_id": "PF3D7_1213900", "name": "EIF2B5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4S8", "map_id": "Q8I4S8", "name": "EIF2B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1250600", "map_id": "PF3D7_1250600", "name": "EIF2B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K977", "map_id": "A0A5K1K977", "name": "EIF2B3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1326400", "map_id": "PF3D7_1326400", "name": "EIF2B3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687925", "map_id": "none", "name": "eIF2:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10687966", "map_id": "none", "name": "eIF2:GDP: eIF2B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10688245", "map_id": "none", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10689620", "map_id": "none", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689618", "map_id": "Q8IIS9", "name": "phospho-p-S1108,S1148,S1192-EIF4G1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689603", "map_id": "Q8I4W3", "name": "phospho-p-S371,T389-RPS6KB1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10689613", "map_id": "none", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687760", "map_id": "Q8IDR9", "name": "RPS6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689610", "map_id": "Q8IDR9", "name": "phospho-p-5S-RPS6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10702534", "map_id": "none", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10693985", "map_id": "Q8I239", "name": "PIP5K1C", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10702417", "map_id": "none", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702413", "map_id": "none", "name": "EPS15,EPN1,EPN2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O97322", "map_id": "O97322", "name": "EPS15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1025000", "map_id": "PF3D7_1025000", "name": "EPS15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJF4", "map_id": "Q8IJF4", "name": "EPS15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4X4", "map_id": "Q8I4X4", "name": "EPN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1245800", "map_id": "PF3D7_1245800", "name": "EPN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702401", "map_id": "none", "name": "UBQLN2,1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8II45", "map_id": "Q8II45", "name": "UBQLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1132000", "map_id": "PF3D7_1132000", "name": "UBQLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIM8", "map_id": "Q8IIM8", "name": "UBQLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2T2", "map_id": "Q8I2T2", "name": "UBQLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702415", "map_id": "none", "name": "UNQLNs:UIM proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702263", "map_id": "none", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698282", "map_id": "Q8IEI4", "name": "NEDD8(1-88)", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702261", "map_id": "none", "name": "STON2,1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IL63", "map_id": "Q8IL63", "name": "NEDD8-STON2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1440700", "map_id": "PF3D7_1440700", "name": "NEDD8-STON2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5M5", "map_id": "Q8I5M5", "name": "NEDD8-STON2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702247", "map_id": "none", "name": "NEDD8-STONs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703640", "map_id": "none", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9648300", "map_id": "none", "name": "chlorpromazine", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702203", "map_id": "none", "name": "AP-2 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3I6", "map_id": "Q8I3I6", "name": "AP2B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0528100", "map_id": "PF3D7_0528100", "name": "AP2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I4W9", "map_id": "Q8I4W9", "name": "AP2A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96254", "map_id": "O96254", "name": "AP2S1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0217300", "map_id": "PF3D7_0217300", "name": "AP2S1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703638", "map_id": "none", "name": "AP2:chlorpromazine", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694563", "map_id": "none", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162212", "map_id": "CHEBI:64182", "name": "DeMQ10H2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162198", "map_id": "CHEBI:64183", "name": "Q10H2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10694560", "map_id": "Q8IBK9", "name": "COQ3(?-369)", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_0724300", "map_id": "PF3D7_0724300", "name": "COQ3(?-369)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694571", "map_id": "none", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_2162214", "map_id": "CHEBI:61011", "name": "all-E-10PrP2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162213", "map_id": "CHEBI:30763", "name": "PHB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162207", "map_id": "CHEBI:64136", "name": "DHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10694568", "map_id": "C6KSS3", "name": "COQ2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_0607500", "map_id": "PF3D7_0607500", "name": "COQ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694574", "map_id": "none", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162209", "map_id": "CHEBI:50775", "name": "DHDB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162215", "map_id": "CHEBI:50776", "name": "MHDB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10694588", "map_id": "none", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162256", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10694585", "map_id": "none", "name": "PDSS1/2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O96130", "map_id": "O96130", "name": "PDSS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0202700", "map_id": "PF3D7_0202700", "name": "PDSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688699", "map_id": "none", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688694", "map_id": "none", "name": "pol II transcription complex containing 9 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10688696", "map_id": "none", "name": "pol II transcription complex containing 11 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687614", "map_id": "none", "name": "RNA Polymerase II (unphosphorylated):TFIIF complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689161", "map_id": "none", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688727", "map_id": "none", "name": "Pol II transcription complex containing extruded transcript to +30", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10694756", "map_id": "none", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5357707", "map_id": "CHEBI:30021", "name": "SeMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5357652", "map_id": "CHEBI:9066", "name": "AdoSeMet", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10703615", "map_id": "none", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9647934", "map_id": "none", "name": "Palmostatin B", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703611", "map_id": "none", "name": "LYPLA1 dimer, ABHD17A,B,C", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I1Z1", "map_id": "Q8I1Z1", "name": "ABHD17C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0403800", "map_id": "PF3D7_0403800", "name": "ABHD17C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4R4", "map_id": "C0H4R4", "name": "ABHD17B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1120400", "map_id": "PF3D7_1120400", "name": "ABHD17B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIG3", "map_id": "Q8IIG3", "name": "ABHD17B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703613", "map_id": "none", "name": "Palmostatin B:LYPLA1 dimer, ABHD17A,B,C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703582", "map_id": "none", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703578", "map_id": "none", "name": "FNTA:FNTB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I503", "map_id": "Q8I503", "name": "FNTA(2-379)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1242600", "map_id": "PF3D7_1242600", "name": "FNTA(2-379)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHP6", "map_id": "Q8IHP6", "name": "FNTB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1147500", "map_id": "PF3D7_1147500", "name": "FNTB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9653479", "map_id": "none", "name": "FNTB inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703580", "map_id": "none", "name": "FNTA:FNTB:FTase inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693680", "map_id": "none", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1474124", "map_id": "CHEBI:18372", "name": "DHNTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1475054", "map_id": "CHEBI:15266", "name": "PPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1474179", "map_id": "CHEBI:17804", "name": "PTHP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693677", "map_id": "none", "name": "p-PTPS hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KTB6", "map_id": "C6KTB6", "name": "PTS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0628000", "map_id": "PF3D7_0628000", "name": "PTS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693669", "map_id": "none", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29460", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693666", "map_id": "none", "name": "GCH1 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I5H7", "map_id": "Q8I5H7", "name": "GCH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1224000", "map_id": "PF3D7_1224000", "name": "GCH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693931", "map_id": "none", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1497857", "map_id": "CHEBI:15375", "name": "BH2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10693929", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10693695", "map_id": "none", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693684", "map_id": "none", "name": "PTPS hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10693692", "map_id": "none", "name": "Homologues of PRKG2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10691489", "map_id": "none", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114519", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_76108", "map_id": "CHEBI:29089", "name": "1,2-daG3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691486", "map_id": "none", "name": "Diacylglycerol kinase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IKC5", "map_id": "Q8IKC5", "name": "DGKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1471400", "map_id": "PF3D7_1471400", "name": "DGKA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2K9", "map_id": "Q8I2K9", "name": "DGKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698647", "map_id": "none", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5694509", "map_id": "CHEBI:75571", "name": "3AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_422506", "map_id": "CHEBI:15843", "name": "AA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10698644", "map_id": "Q8IBH1", "name": "ABHD12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0728700", "map_id": "PF3D7_0728700", "name": "ABHD12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692642", "map_id": "none", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692638", "map_id": "Q8I3T2", "name": "CAPZB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0517600", "map_id": "PF3D7_0517600", "name": "CAPZB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692633", "map_id": "Q8I3I2", "name": "CAPZA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0528500", "map_id": "PF3D7_0528500", "name": "CAPZA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692640", "map_id": "none", "name": "F-actin capping protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3I2", "map_id": "Q8I3I2", "name": "CAPZA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3T2", "map_id": "Q8I3T2", "name": "CAPZB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693489", "map_id": "none", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113573", "map_id": "CHEBI:15996", "name": "GTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113525", "map_id": "CHEBI:17552", "name": "GDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10693486", "map_id": "Q8IJV6", "name": "AK3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1008900", "map_id": "PF3D7_1008900", "name": "AK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693458", "map_id": "none", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693431", "map_id": "none", "name": "Homologues of CENPE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I4X5", "map_id": "Q8I4X5", "name": "CENPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1245600", "map_id": "PF3D7_1245600", "name": "CENPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5U0", "map_id": "Q8I5U0", "name": "CENPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693433", "map_id": "none", "name": "CENP-E dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693456", "map_id": "none", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693410", "map_id": "O77382", "name": "KIF11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0317500", "map_id": "PF3D7_0317500", "name": "KIF11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693412", "map_id": "none", "name": "Kinesin-5 homotetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77382", "map_id": "O77382", "name": "KIF11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693480", "map_id": "none", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10693476", "map_id": "none", "name": "Histone H3 methylated at lysine-9", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IDZ1", "map_id": "Q8IDZ1", "name": "MeK-H3F3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1333700", "map_id": "PF3D7_1333700", "name": "MeK-H3F3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSV0", "map_id": "C6KSV0", "name": "MeK10-HIST1H3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0617900", "map_id": "PF3D7_0617900", "name": "MeK10-HIST1H3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KT19", "map_id": "C6KT19", "name": "MeK10-HIST1H3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693463", "map_id": "Q8I5K4", "name": "CBX5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1220900", "map_id": "PF3D7_1220900", "name": "CBX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693478", "map_id": "none", "name": "HP1alpha:Histone H3 methylated at K9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I5K4", "map_id": "Q8I5K4", "name": "CBX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703621", "map_id": "none", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703617", "map_id": "Q8I2Y2", "name": "OGG1beta", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703619", "map_id": "Q8I2Y2", "name": "OGG1beta", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10689008", "map_id": "none", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689003", "map_id": "none", "name": "MUTYH:(8oxoG:Ade)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689024", "map_id": "none", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689021", "map_id": "none", "name": "MPG:EtAD-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110249", "map_id": "CHEBI:29146", "name": "EtAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689031", "map_id": "none", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689028", "map_id": "none", "name": "MPG:Hyp-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689017", "map_id": "none", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689012", "map_id": "none", "name": "MPG:MADE-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30947", "map_id": "CHEBI:38635", "name": "MADE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688985", "map_id": "none", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688980", "map_id": "none", "name": "OGG1:(8oxoG:Cyt)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110242", "map_id": "CHEBI:44605", "name": "8oxoG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689062", "map_id": "none", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689051", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I347", "map_id": "Q8I347", "name": "REV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0910500", "map_id": "PF3D7_0910500", "name": "REV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689059", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689109", "map_id": "none", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689067", "map_id": "A0A143ZYZ7", "name": "REV3L", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1037000", "map_id": "PF3D7_1037000", "name": "REV3L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689072", "map_id": "Q8IJH1", "name": "MAD2L2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1023400", "map_id": "PF3D7_1023400", "name": "MAD2L2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689074", "map_id": "none", "name": "POLZ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IJH1", "map_id": "Q8IJH1", "name": "MAD2L2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A143ZYZ7", "map_id": "A0A143ZYZ7", "name": "REV3L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689083", "map_id": "none", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689076", "map_id": "none", "name": "POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10689080", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697018", "map_id": "none", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10689053", "map_id": "none", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689036", "map_id": "Q8I347", "name": "REV1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10689049", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697056", "map_id": "none", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697052", "map_id": "none", "name": "PCNA:RPA:RFC:TLS-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10689135", "map_id": "none", "name": "POLD,POLE", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10697054", "map_id": "none", "name": "PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697153", "map_id": "none", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697144", "map_id": "none", "name": "POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10697150", "map_id": "none", "name": "POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697162", "map_id": "none", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697159", "map_id": "none", "name": "POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689107", "map_id": "none", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689097", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10689104", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697094", "map_id": "none", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697090", "map_id": "none", "name": "NPLOC4:UFD1L:VCP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILR6", "map_id": "Q8ILR6", "name": "UFD1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1418000", "map_id": "PF3D7_1418000", "name": "UFD1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I426", "map_id": "Q8I426", "name": "NPLOC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0507700", "map_id": "PF3D7_0507700", "name": "NPLOC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697074", "map_id": "none", "name": "SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IDU9", "map_id": "Q8IDU9", "name": "SPRTN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1338400", "map_id": "PF3D7_1338400", "name": "SPRTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697092", "map_id": "none", "name": "NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697096", "map_id": "none", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697072", "map_id": "Q8IDU9", "name": "SPRTN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689100", "map_id": "none", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689091", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697125", "map_id": "none", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697116", "map_id": "none", "name": "POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10697122", "map_id": "none", "name": "POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697134", "map_id": "none", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697131", "map_id": "none", "name": "POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10703478", "map_id": "none", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703474", "map_id": "none", "name": "Homologues of CAMK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H482", "map_id": "C0H482", "name": "CAMK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1450000", "map_id": "PF3D7_1450000", "name": "CAMK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKX5", "map_id": "Q8IKX5", "name": "CAMK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4K5", "map_id": "C0H4K5", "name": "CAMK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSQ1", "map_id": "C6KSQ1", "name": "CAMK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703476", "map_id": "none", "name": "CAMK1:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703452", "map_id": "none", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703445", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10703449", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703397", "map_id": "none", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10703385", "map_id": "none", "name": "p-S221,T359.S363,S380,T573,T732-RSK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10703395", "map_id": "none", "name": "p-S221,T359,S363,S380,T573,T732-RSK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10690163", "map_id": "none", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193707", "map_id": "CHEBI:63830", "name": "5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193728", "map_id": "CHEBI:63834", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690143", "map_id": "Q8IM05", "name": "AKR1C4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690161", "map_id": "none", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193760", "map_id": "CHEBI:63829", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_213285", "map_id": "CHEBI:63831", "name": "5beta-cholestan-3alpha,7alpha,24(S)-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690159", "map_id": "none", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193745", "map_id": "CHEBI:63839", "name": "4CHOL7a,12a,24(S)TONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10690138", "map_id": "Q8IM05", "name": "AKR1D1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690157", "map_id": "none", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193724", "map_id": "CHEBI:63838", "name": "4CHOL7a,24(S)DONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10702531", "map_id": "none", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8868399", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8868400", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10702528", "map_id": "none", "name": "OSBPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8II47", "map_id": "Q8II47", "name": "OSBPL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1131800", "map_id": "PF3D7_1131800", "name": "OSBPL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690167", "map_id": "none", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9617026", "map_id": "CHEBI:48833", "name": "4CHOL7a,12a,27TONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_193829", "map_id": "CHEBI:48834", "name": "5beta-cholestan-7alpha,12alpha,27-triol-3-one", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690165", "map_id": "none", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193843", "map_id": "CHEBI:17278", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690171", "map_id": "none", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193830", "map_id": "CHEBI:48778", "name": "5beta-cholestan-7alpha,27-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193842", "map_id": "CHEBI:28540", "name": "5beta-cholestan-3alpha,7alpha,26-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690169", "map_id": "none", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193835", "map_id": "CHEBI:48825", "name": "4CHOL7a,27DONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10702539", "map_id": "none", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1806217", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_8868393", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_1806234", "map_id": "CHEBI:17526", "name": "PI4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10702536", "map_id": "Q8II47", "name": "OSBP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690146", "map_id": "none", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192064", "map_id": "CHEBI:2288", "name": "5beta-cholesten-7alpha, 12alpha-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192087", "map_id": "CHEBI:16496", "name": "5beta-cholestan-3alpha,7alpha,12alpha-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690150", "map_id": "none", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191980", "map_id": "CHEBI:2290", "name": "5beta-cholestan-7alpha-ol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192030", "map_id": "CHEBI:28047", "name": "5beta-cholestan-3alpha,7alpha-diol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690148", "map_id": "none", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192195", "map_id": "CHEBI:28477", "name": "4CHOL7a,12aDONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10690141", "map_id": "none", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192136", "map_id": "CHEBI:17899", "name": "4CHOL7aOLONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10690097", "map_id": "none", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191324", "map_id": "CHEBI:16057", "name": "DMAPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191362", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191409", "map_id": "CHEBI:17211", "name": "GPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690091", "map_id": "none", "name": "2(FDPS:3Mg2+)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8II79", "map_id": "Q8II79", "name": "FDPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1128400", "map_id": "PF3D7_1128400", "name": "FDPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690094", "map_id": "none", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191385", "map_id": "CHEBI:17407", "name": "FAPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10696462", "map_id": "none", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_193384", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10696459", "map_id": "Q8IJT2", "name": "ARV1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1011300", "map_id": "PF3D7_1011300", "name": "ARV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10700978", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1500590", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_1524101", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10700973", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q8I227", "map_id": "Q8I227", "name": "TRIAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0111900", "map_id": "PF3D7_0111900", "name": "TRIAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE73", "map_id": "Q8IE73", "name": "PRELID1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1324400", "map_id": "PF3D7_1324400", "name": "PRELID1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10700975", "map_id": "none", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_10700971", "map_id": "none", "name": "PRELID1, PRELID3A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_10700962", "map_id": "Q8I227", "name": "TRIAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10703356", "map_id": "none", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024522", "map_id": "CHEBI:138590", "name": "17(R)-Hp-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024463", "map_id": "CHEBI:91137", "name": "17(R)-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10703366", "map_id": "none", "name": "EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025001", "map_id": "CHEBI:132228", "name": "13(S),14(S)-epoxy-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9025011", "map_id": "CHEBI:138248", "name": "MaR2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10703358", "map_id": "none", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024012", "map_id": "CHEBI:136113", "name": "17(S)-Hp-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024815", "map_id": "CHEBI:138640", "name": "17(S)-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10696999", "map_id": "none", "name": "Oxidative damage to the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689130", "map_id": "none", "name": "APEX1:SSB(AP->5'-dRP)-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10696997", "map_id": "none", "name": "APEX1:SSB(5'-ddRP)-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689156", "map_id": "none", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689152", "map_id": "none", "name": "APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10689154", "map_id": "none", "name": "LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IES4", "map_id": "Q8IES4", "name": "LIG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697012", "map_id": "none", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697009", "map_id": "none", "name": "LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689148", "map_id": "none", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689145", "map_id": "none", "name": "APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q7K734", "map_id": "Q7K734", "name": "FEN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689141", "map_id": "none", "name": "APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10698360", "map_id": "none", "name": "APEH hydrolyses NAc-Ser-protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5691496", "map_id": "none", "name": "NAc-Ser:protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_5691517", "map_id": "CHEBI:83690", "name": "NAc-Ser residue", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6785226", "map_id": "CHEBI:36080", "name": "protein", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698357", "map_id": "O97289", "name": "APEH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10700732", "map_id": "none", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10700710", "map_id": "none", "name": "ETF1 dimer:eRF3:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10700717", "map_id": "none", "name": "Me-Q185-ETF1 dimer:eRF3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703116", "map_id": "none", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10703109", "map_id": "Q8I1S2", "name": "MAF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0416500", "map_id": "PF3D7_0416500", "name": "MAF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703107", "map_id": "Q8I1S2", "name": "MAF1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694753", "map_id": "none", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395868", "map_id": "CHEBI:65119", "name": "2-hydroxy-ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395878", "map_id": "CHEBI:65129", "name": "2-hydroxy-AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694745", "map_id": "none", "name": "NUDT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDK8", "map_id": "Q8IDK8", "name": "NUDT1-4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1349100", "map_id": "PF3D7_1349100", "name": "NUDT1-4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694751", "map_id": "none", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395852", "map_id": "CHEBI:63220", "name": "8-oxo-dGTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395817", "map_id": "CHEBI:63223", "name": "8-oxo-dGMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694748", "map_id": "none", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395822", "map_id": "CHEBI:63208", "name": "2-hydroxy-dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395855", "map_id": "CHEBI:63211", "name": "2-hydroxy-dAMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10698420", "map_id": "none", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10698407", "map_id": "none", "name": "GCSH:DHLL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8II35", "map_id": "Q8II35", "name": "GCSH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1132900", "map_id": "PF3D7_1132900", "name": "GCSH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:50746", "map_id": "CHEBI:50746", "name": "CHEBI:50746", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698401", "map_id": "Q8II35", "name": "lipoyl-K107-GCSH", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10698417", "map_id": "none", "name": "DLD dimer:2xFAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I5A0", "map_id": "Q8I5A0", "name": "DLD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1232200", "map_id": "PF3D7_1232200", "name": "DLD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698415", "map_id": "none", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_200671", "map_id": "CHEBI:15635", "name": "THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10698405", "map_id": "none", "name": "GCSH:SAMDLL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:14949", "map_id": "CHEBI:14949", "name": "CHEBI:14949", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5693978", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693984", "map_id": "CHEBI:12071", "name": "5,10-methylene-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10698412", "map_id": "Q8I6T0", "name": "AMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1365500", "map_id": "PF3D7_1365500", "name": "AMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697634", "map_id": "none", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689705", "map_id": "none", "name": "K63polyUb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689703", "map_id": "none", "name": "K63-Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10697631", "map_id": "none", "name": "ATXN3,ATXN3L,JOSD1,JOSD2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I5F0", "map_id": "Q8I5F0", "name": "ATXN3L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1226800", "map_id": "PF3D7_1226800", "name": "ATXN3L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIP4", "map_id": "Q8IIP4", "name": "JOSD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1111900", "map_id": "PF3D7_1111900", "name": "JOSD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697618", "map_id": "none", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697614", "map_id": "Q8I5F0", "name": "ATXN3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10697609", "map_id": "none", "name": "RAD23", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IJS8", "map_id": "Q8IJS8", "name": "RAD23B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1011700", "map_id": "PF3D7_1011700", "name": "RAD23B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697616", "map_id": "none", "name": "ATXN3:RAD23", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10698080", "map_id": "none", "name": "PARK2 autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698072", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10693227", "map_id": "O97226", "name": "PARK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0303800", "map_id": "PF3D7_0303800", "name": "ARIH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697641", "map_id": "O97226", "name": "polyUb-PARK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10697638", "map_id": "none", "name": "ATXN3 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10697078", "map_id": "none", "name": "VCP hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10697636", "map_id": "none", "name": "ATXN3:VCP hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10698075", "map_id": "none", "name": "ATXN3 deubiquitinates polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697643", "map_id": "none", "name": "ATXN3:polyUb-PARK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O97226", "map_id": "O97226", "name": "ARIH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697645", "map_id": "none", "name": "ATXN3:PARK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10698077", "map_id": "none", "name": "ATXN3 binds polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697620", "map_id": "Q8I5F0", "name": "ATXN3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10703328", "map_id": "none", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9012375", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10696164", "map_id": "Q8ILE3", "name": "VDAC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "PF3D7_1432100", "map_id": "PF3D7_1432100", "name": "VDAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699253", "map_id": "none", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694130", "map_id": "CHEBI:15694", "name": "(R)-S-LGSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699250", "map_id": "none", "name": "HAGH-2:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H490", "map_id": "C0H490", "name": "HAGH-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0406400", "map_id": "PF3D7_0406400", "name": "HAGH-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698430", "map_id": "none", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694074", "map_id": "CHEBI:17158", "name": "MGXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698427", "map_id": "none", "name": "GLO1 dimer:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIM5", "map_id": "Q8IIM5", "name": "GLO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1113700", "map_id": "PF3D7_1113700", "name": "GLO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696882", "map_id": "none", "name": "ATAT acetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691147", "map_id": "none", "name": "Microtubule", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10696874", "map_id": "none", "name": "acetylated microtubule", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10696879", "map_id": "C0H559", "name": "ATAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PFI1220w", "map_id": "PFI1220w", "name": "ATAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696885", "map_id": "none", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696504", "map_id": "Q8IJW3", "name": "HDAC6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10697600", "map_id": "none", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_5688282", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10697590", "map_id": "none", "name": "Homologues of AcK-CYCS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q8I6T6", "map_id": "Q8I6T6", "name": "CYCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1404100", "map_id": "PF3D7_1404100", "name": "CYCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IM53", "map_id": "Q8IM53", "name": "CYCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5688281", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10689386", "map_id": "none", "name": "Homologues of CYCS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_5688340", "map_id": "CHEBI:76279", "name": "2'-O-acetyl-ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10697597", "map_id": "none", "name": "SIRT5:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q8IE47", "map_id": "Q8IE47", "name": "Sir2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF13_0152", "map_id": "PF13_0152", "name": "Sir2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689159", "map_id": "none", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73578", "map_id": "CHEBI:78679", "name": "R5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_110644", "map_id": "CHEBI:16284", "name": "dATP", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109386", "map_id": "CHEBI:17713", "name": "2'-deoxyadenosine 5'-monophosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10688285", "map_id": "none", "name": "PRPS1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IE40", "map_id": "Q8IE40", "name": "PRPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1327800", "map_id": "PF3D7_1327800", "name": "PRPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE67", "map_id": "Q8IE67", "name": "PRPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688292", "map_id": "none", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688289", "map_id": "none", "name": "PRPS2 dimer, PRPS1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689586", "map_id": "none", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688553", "map_id": "Q8IL28", "name": "AGPAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693747", "map_id": "none", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500596", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498728", "map_id": "CHEBI:17389", "name": "2-MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524021", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10693732", "map_id": "none", "name": "PNPLA2/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O96266", "map_id": "O96266", "name": "PNPLA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693744", "map_id": "none", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500594", "map_id": "CHEBI:17855", "name": "TAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693735", "map_id": "none", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10693737", "map_id": "none", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10693759", "map_id": "none", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10688689", "map_id": "none", "name": "DGAT1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10703201", "map_id": "none", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8954997", "map_id": "CHEBI:1582", "name": "3MT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703198", "map_id": "Q8IKF4", "name": "LRTOMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691072", "map_id": "none", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691070", "map_id": "none", "name": "COMT:COMT inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8IKF4", "map_id": "Q8IKF4", "name": "LRTOMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703636", "map_id": "none", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9679778", "map_id": "none", "name": "COMT inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10701636", "map_id": "none", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10701627", "map_id": "none", "name": "ARF1:GTP:CYTH1,2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10701633", "map_id": "none", "name": "ARF1:GDP:CYTH1,2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10701609", "map_id": "none", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10701605", "map_id": "none", "name": "STX:PalmC-YKT6:BET1L:GOSR1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "C0H5D3", "map_id": "C0H5D3", "name": "PalmC-YKT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1324700", "map_id": "PF3D7_1324700", "name": "PalmC-YKT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKE6", "map_id": "Q8IKE6", "name": "GOSR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1469100", "map_id": "PF3D7_1469100", "name": "GOSR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701607", "map_id": "none", "name": "STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10701629", "map_id": "none", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10701617", "map_id": "none", "name": "CYTH1,2,3,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10694050", "map_id": "none", "name": "ARF1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10703441", "map_id": "none", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703437", "map_id": "none", "name": "Tail-anchored proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I599", "map_id": "Q8I599", "name": "CYB5A-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1232300", "map_id": "PF3D7_1232300", "name": "CYB5A-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96183", "map_id": "O96183", "name": "SEC61G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0210000", "map_id": "PF3D7_0210000", "name": "SEC61G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I655", "map_id": "Q8I655", "name": "SERP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0219400.1", "map_id": "PF3D7_0219400.1", "name": "SERP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4S2", "map_id": "C0H4S2", "name": "OTOF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0806300", "map_id": "PF3D7_0806300", "name": "OTOF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4W6", "map_id": "C0H4W6", "name": "SEC61B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0821800", "map_id": "PF3D7_0821800", "name": "SEC61B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703409", "map_id": "none", "name": "SGTA dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77346", "map_id": "O77346", "name": "SGTA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0312200", "map_id": "PF3D7_0312200", "name": "SGTA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703439", "map_id": "none", "name": "Tail-anchored protein:SGTA dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694386", "map_id": "none", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10694380", "map_id": "Q8ID24", "name": "4xHC-TIMM10B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_1368600", "map_id": "PF3D7_1368600", "name": "4xHC-TIMM9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694378", "map_id": "none", "name": "TIMM9:TIMM10:Protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q8ID24", "map_id": "Q8ID24", "name": "4xHC-TIMM9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5W2", "map_id": "Q8I5W2", "name": "4xHC-TIMM10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1208600", "map_id": "PF3D7_1208600", "name": "4xHC-TIMM10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694353", "map_id": "C6KTB0", "name": "TIMM22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_0627400", "map_id": "PF3D7_0627400", "name": "TIMM22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694384", "map_id": "none", "name": "TIMM9:TIMM10:TIMM10B:TIM22:Protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "C6KTB0", "map_id": "C6KTB0", "name": "TIMM22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687270", "map_id": "none", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687267", "map_id": "none", "name": "ASNS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77330", "map_id": "O77330", "name": "ASNS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0309500", "map_id": "PF3D7_0309500", "name": "ASNS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687260", "map_id": "none", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10703196", "map_id": "none", "name": "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8954466", "map_id": "CHEBI:21547", "name": "NAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10703193", "map_id": "Q8IL96", "name": "NAT8L", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1437000", "map_id": "PF3D7_1437000", "name": "NAT8L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691653", "map_id": "none", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691634", "map_id": "Q8I2Z4", "name": "phospho-p-S132-COL4A3BP-2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0915800", "map_id": "PF3D7_0915800", "name": "PLEKHA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10691638", "map_id": "Q8I2Z4", "name": "phospho-p-S,S132,T-COL4A3BP-2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10691668", "map_id": "none", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_429785", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_428270", "map_id": "CHEBI:17761", "name": "CERA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_429773", "map_id": "CHEBI:18035", "name": "DAGs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_429789", "map_id": "CHEBI:17636", "name": "SPHM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10691665", "map_id": "C6KT87", "name": "SGMS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "PF3D7_0625100", "map_id": "PF3D7_0625100", "name": "SAMD8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691663", "map_id": "none", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429802", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_429807", "map_id": "CHEBI:17761", "name": "CERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_429776", "map_id": "CHEBI:17636", "name": "SPHM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_112275", "map_id": "CHEBI:18035", "name": "DAGs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10691660", "map_id": "C6KT87", "name": "2xPalmC-SGMS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10691582", "map_id": "none", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428139", "map_id": "CHEBI:15541", "name": "ST-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428163", "map_id": "CHEBI:16566", "name": "SPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_428126", "map_id": "CHEBI:31488", "name": "DHCE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10691579", "map_id": "none", "name": "LASS proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8IM57", "map_id": "Q8IM57", "name": "CERS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1403700", "map_id": "PF3D7_1403700", "name": "CERS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703662", "map_id": "none", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428203", "map_id": "CHEBI:37550", "name": "S1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_419305", "map_id": "CHEBI:37550", "name": "S1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10703659", "map_id": "none", "name": "Homologues of SPNS2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "C6KSY4", "map_id": "C6KSY4", "name": "SPNS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0916000", "map_id": "PF3D7_0916000", "name": "SPNS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I2Z2", "map_id": "Q8I2Z2", "name": "SPNS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703229", "map_id": "none", "name": "SAMD8 transforms PE and CERA to CPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8959490", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_8959486", "map_id": "CHEBI:17761", "name": "CERA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_8959463", "map_id": "CHEBI:73204", "name": "CPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10703226", "map_id": "C6KT87", "name": "SAMD8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10692484", "map_id": "none", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532562", "map_id": "CHEBI:17369", "name": "Man6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692481", "map_id": "Q8IAL6", "name": "MPI", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0801800", "map_id": "PF3D7_0801800", "name": "MPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692090", "map_id": "none", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532531", "map_id": "CHEBI:35374", "name": "Man1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692087", "map_id": "none", "name": "PMM1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJM5", "map_id": "Q8IJM5", "name": "PMM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1017400", "map_id": "PF3D7_1017400", "name": "PMM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692499", "map_id": "none", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29508", "map_id": "CHEBI:15531", "name": "Mal-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200993", "map_id": "CHEBI:15525", "name": "PALM-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_548812", "map_id": "CHEBI:50571", "name": "3OOD-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692496", "map_id": "none", "name": "ELOVL3,6,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8I251", "map_id": "Q8I251", "name": "ELOVL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0109300", "map_id": "PF3D7_0109300", "name": "ELOVL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690466", "map_id": "none", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3632881", "map_id": "CHEBI:15756", "name": "PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690463", "map_id": "none", "name": "ACSL1,3,5,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8I3L4", "map_id": "Q8I3L4", "name": "ACSL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1238800", "map_id": "PF3D7_1238800", "name": "ACSL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I535", "map_id": "Q8I535", "name": "ACSL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692511", "map_id": "none", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_548809", "map_id": "CHEBI:50570", "name": "TOD-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692508", "map_id": "none", "name": "TECR,TECRL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8II05", "map_id": "Q8II05", "name": "TECR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1135900", "map_id": "PF3D7_1135900", "name": "TECR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697326", "map_id": "none", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5676631", "map_id": "CHEBI:15456", "name": "VLC3HA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5676634", "map_id": "CHEBI:50998", "name": "2,3-TE-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10697323", "map_id": "none", "name": "PTPLs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "C0H5F1", "map_id": "C0H5F1", "name": "PTPLB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1331600", "map_id": "PF3D7_1331600", "name": "PTPLB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692492", "map_id": "none", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_548819", "map_id": "CHEBI:15514", "name": "AA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_548816", "map_id": "CHEBI:63821", "name": "3ODCT-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692489", "map_id": "Q8I251", "name": "ELOVL3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10698277", "map_id": "none", "name": "SCD desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4085415", "map_id": "CHEBI:16518", "name": "Fe(2+)Cb5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4085425", "map_id": "CHEBI:18097", "name": "Fe(3+)Cb5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5690558", "map_id": "CHEBI:15534", "name": "OLE-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10698274", "map_id": "none", "name": "SCD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8I0W9", "map_id": "Q8I0W9", "name": "SCD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0511200", "map_id": "PF3D7_0511200", "name": "SCD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701599", "map_id": "none", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10701596", "map_id": "none", "name": "SCD5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10698099", "map_id": "none", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5690540", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_164991", "map_id": "CHEBI:33184", "name": "LCFA-CoA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:61907", "map_id": "CHEBI:61907", "name": "CHEBI:61907", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5690519", "map_id": "none", "name": "MCFA, LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:59554", "map_id": "CHEBI:59554", "name": "CHEBI:59554", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698096", "map_id": "O96259", "name": "ACOT9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_0217900", "map_id": "PF3D7_0217900", "name": "ACOT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701663", "map_id": "none", "name": "ACBD6 binds LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701659", "map_id": "none", "name": "Homologues of ACBD6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IBL1", "map_id": "Q8IBL1", "name": "ACBD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1119000", "map_id": "PF3D7_1119000", "name": "ACBD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIH7", "map_id": "Q8IIH7", "name": "ACBD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701661", "map_id": "none", "name": "ACBD6:LCFA-CoA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694426", "map_id": "none", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046066", "map_id": "CHEBI:15531", "name": "Malonyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046052", "map_id": "CHEBI:63545", "name": "SDA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113601", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113519", "map_id": "CHEBI:15377", "name": "H2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113564", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046051", "map_id": "CHEBI:63542", "name": "ETA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_162743", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_159751", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10694424", "map_id": "none", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211579", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046056", "map_id": "CHEBI:27432", "name": "ALA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046064", "map_id": "CHEBI:16027", "name": "adenosine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046049", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046062", "map_id": "CHEBI:51985", "name": "ALA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10694421", "map_id": "none", "name": "ACSL1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10694430", "map_id": "none", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2046044", "map_id": "CHEBI:17351", "name": "LINA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046063", "map_id": "CHEBI:15530", "name": "LA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10694428", "map_id": "none", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046042", "map_id": "CHEBI:15508", "name": "GLA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046045", "map_id": "CHEBI:27979", "name": "DGL-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10694555", "map_id": "none", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142811", "map_id": "CHEBI:15626", "name": "12S-HpETE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142678", "map_id": "CHEBI:34146", "name": "12S-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694540", "map_id": "Q8I5T2", "name": "L-selenocysteine-residue-GPX4(?-197)", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694543", "map_id": "none", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142790", "map_id": "CHEBI:34145", "name": "12R-HpETE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142716", "map_id": "CHEBI:34144", "name": "12R-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694529", "map_id": "none", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_879629", "map_id": "CHEBI:15555", "name": "PGD2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142710", "map_id": "CHEBI:27595", "name": "11epi-PGF2a", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694534", "map_id": "none", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265283", "map_id": "CHEBI:15554", "name": "PGH2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694531", "map_id": "none", "name": "HPGDS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694526", "map_id": "none", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_879535", "map_id": "CHEBI:15553", "name": "PGF2a", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690909", "map_id": "none", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265287", "map_id": "CHEBI:15551", "name": "PGE2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690906", "map_id": "none", "name": "Homologues of PTGES3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H473", "map_id": "C0H473", "name": "PTGES3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1453700", "map_id": "PF3D7_1453700", "name": "PTGES3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKU1", "map_id": "Q8IKU1", "name": "PTGES3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A1J3", "map_id": "A0A144A1J3", "name": "PTGES3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693717", "map_id": "none", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498730", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10693708", "map_id": "none", "name": "LPGAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693711", "map_id": "none", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498740", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693714", "map_id": "none", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524028", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_426925", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10693703", "map_id": "none", "name": "LPCAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693755", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693752", "map_id": "A0A5K1K9G0", "name": "PNPLA8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1358000", "map_id": "PF3D7_1358000", "name": "PNPLA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693706", "map_id": "none", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_975614", "map_id": "CHEBI:16728", "name": "2-acyl LPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693739", "map_id": "none", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498738", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10688567", "map_id": "none", "name": "Homologues of LPCAT4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693723", "map_id": "none", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498729", "map_id": "CHEBI:28936", "name": "2-acyl LPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693757", "map_id": "none", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10693720", "map_id": "none", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498724", "map_id": "CHEBI:52603", "name": "1-acyl LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693741", "map_id": "none", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498722", "map_id": "CHEBI:37646", "name": "2-acyl LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693923", "map_id": "none", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1498751", "map_id": "CHEBI:16000", "name": "ETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428686", "map_id": "CHEBI:17553", "name": "PETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693920", "map_id": "none", "name": "CHK/ETNK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIB7", "map_id": "Q8IIB7", "name": "ETNK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1124600", "map_id": "PF3D7_1124600", "name": "ETNK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IM71", "map_id": "Q8IM71", "name": "ETNK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1401800", "map_id": "PF3D7_1401800", "name": "ETNK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693778", "map_id": "none", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500603", "map_id": "CHEBI:16732", "name": "CDP-ETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693775", "map_id": "none", "name": "CEPT1/EPT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "C6KTB9", "map_id": "C6KTB9", "name": "EPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0628300.1", "map_id": "PF3D7_0628300.1", "name": "EPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693889", "map_id": "none", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_110614", "map_id": "CHEBI:17677", "name": "CTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693886", "map_id": "none", "name": "PCYT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8IDM2", "map_id": "Q8IDM2", "name": "PCYT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1347700", "map_id": "PF3D7_1347700", "name": "PCYT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693900", "map_id": "none", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693897", "map_id": "none", "name": "LPIN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693906", "map_id": "none", "name": "PC:PITPNB is transported from the Golgi membrane to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10693849", "map_id": "none", "name": "PC:PITPNB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q8IDI9", "map_id": "Q8IDI9", "name": "PITPNM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1351000", "map_id": "PF3D7_1351000", "name": "PITPNM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693904", "map_id": "none", "name": "PC:PITPNB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693910", "map_id": "none", "name": "PC is exchanged with PI by PITPNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426639", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10693908", "map_id": "none", "name": "PI:PITPNB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693925", "map_id": "none", "name": "PI:PITPNB is transported from the ER membrane to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693847", "map_id": "none", "name": "PI:PITPNB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10703182", "map_id": "none", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_2173763", "map_id": "CHEBI:60479", "name": "lysoPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8954142", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8952253", "map_id": "CHEBI:16870", "name": "GPCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10703179", "map_id": "C6KTC8", "name": "PLA2G15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10693795", "map_id": "none", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426955", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_426910", "map_id": "CHEBI:17268", "name": "Ins", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693792", "map_id": "none", "name": "CDIPT:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "C0H5B7", "map_id": "C0H5B7", "name": "CDIPT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1315600", "map_id": "PF3D7_1315600", "name": "CDIPT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702550", "map_id": "none", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_426658", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10702547", "map_id": "none", "name": "PITPNM1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693869", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693866", "map_id": "none", "name": "CDS1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8ILZ6", "map_id": "Q8ILZ6", "name": "CDS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1409900", "map_id": "PF3D7_1409900", "name": "CDS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693859", "map_id": "none", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693856", "map_id": "C0H5K9", "name": "PTDSS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1366800", "map_id": "PF3D7_1366800", "name": "PTDSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693879", "map_id": "none", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693876", "map_id": "C0H5K9", "name": "PTDSS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10693824", "map_id": "none", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1524071", "map_id": "CHEBI:36700", "name": "PCho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693821", "map_id": "none", "name": "CHK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693840", "map_id": "none", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524060", "map_id": "CHEBI:16436", "name": "CDP-Cho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693837", "map_id": "none", "name": "PCYT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8IEE9", "map_id": "Q8IEE9", "name": "PCYT1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1316600", "map_id": "PF3D7_1316600", "name": "PCYT1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693769", "map_id": "none", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10693766", "map_id": "none", "name": "CEPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10693785", "map_id": "none", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524057", "map_id": "CHEBI:17815", "name": "DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10693782", "map_id": "none", "name": "CHPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10702281", "map_id": "none", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8865642", "map_id": "CHEBI:64567", "name": "LPC (22:6)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8865629", "map_id": "CHEBI:64567", "name": "LPC (22:6)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702278", "map_id": "Q8I3H5", "name": "MFSD2A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "PF3D7_0529200", "map_id": "PF3D7_0529200", "name": "MFSD2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693874", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524064", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10693871", "map_id": "Q8ILZ6", "name": "CDS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10694115", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806276", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10694015", "map_id": "none", "name": "PIP5K1A/B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694018", "map_id": "none", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10694081", "map_id": "none", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694078", "map_id": "none", "name": "INPP5(2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A143ZZC6", "map_id": "A0A143ZZC6", "name": "SYNJ2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1111600", "map_id": "PF3D7_1111600", "name": "SYNJ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IC15", "map_id": "Q8IC15", "name": "OCRL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0705500", "map_id": "PF3D7_0705500", "name": "OCRL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693990", "map_id": "none", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10694086", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694040", "map_id": "none", "name": "SYNJs,OCRL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694091", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694088", "map_id": "none", "name": "MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694120", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694117", "map_id": "none", "name": "PIP4K2/5K1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694129", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694126", "map_id": "none", "name": "SYNJ/INPP5(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694132", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10694043", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10702655", "map_id": "none", "name": "PLEKHA3,8 bind PI4P, ARF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10690955", "map_id": "Q7KQL3", "name": "ARF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10702651", "map_id": "none", "name": "PLEKHA3,8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q8I2Z4", "map_id": "Q8I2Z4", "name": "PLEKHA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702653", "map_id": "none", "name": "ARF1:PLEKHA3,8:PI4P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10694109", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10694106", "map_id": "Q8IDF9", "name": "SACM1L", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10694083", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524146", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_1806159", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10694112", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10694101", "map_id": "Q8IDF9", "name": "SACM1L", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10694055", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10694052", "map_id": "none", "name": "ARF1/3:GTP:PI4KB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q8I406", "map_id": "Q8I406", "name": "PI4KB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0509800", "map_id": "PF3D7_0509800", "name": "PI4KB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694023", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806165", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10694020", "map_id": "Q8IC15", "name": "OCRL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694104", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10694124", "map_id": "none", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10694122", "map_id": "Q8I406", "name": "PI4KB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694093", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806195", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806198", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "reaction_10688692", "map_id": "none", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_75967", "map_id": "CHEBI:37554", "name": "FACoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10688586", "map_id": "none", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688583", "map_id": "none", "name": "GK,GK2,GK3P", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDI4", "map_id": "Q8IDI4", "name": "GK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1351600", "map_id": "PF3D7_1351600", "name": "GK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688682", "map_id": "none", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688679", "map_id": "none", "name": "LPIN1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10688368", "map_id": "none", "name": "2 acetyl-CoA <=> acetoacetyl-CoA + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73871", "map_id": "CHEBI:15345", "name": "ACA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687343", "map_id": "none", "name": "ACAT1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IKW7", "map_id": "Q8IKW7", "name": "ACAT1(35-427)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1450900", "map_id": "PF3D7_1450900", "name": "ACAT1(35-427)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696583", "map_id": "none", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5340315", "map_id": "CHEBI:24402", "name": "GSL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_5340299", "map_id": "CHEBI:24402", "name": "GSL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10696580", "map_id": "Q8I2Z4", "name": "GLTP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693976", "map_id": "none", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1610735", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10693973", "map_id": "none", "name": "SMPD2,3:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8I537", "map_id": "Q8I537", "name": "SMPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1238600", "map_id": "PF3D7_1238600", "name": "SMPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702983", "map_id": "none", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10702972", "map_id": "Q8IB24", "name": "HSPA8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10702975", "map_id": "Q8IB24", "name": "Me3K561-HSPA8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10702980", "map_id": "Q8IHT8", "name": "METTL21A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1142700", "map_id": "PF3D7_1142700", "name": "VCPKMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703019", "map_id": "none", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689442", "map_id": "Q8I0P6", "name": "EEF1A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703011", "map_id": "Q8I0P6", "name": "Me3K318-EEF1A1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703016", "map_id": "Q8I2Y6", "name": "METTL10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0916600", "map_id": "PF3D7_0916600", "name": "METTL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10703002", "map_id": "none", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696509", "map_id": "C6KT34", "name": "VCP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702997", "map_id": "C6KT34", "name": "Me3K315-VCP", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10702999", "map_id": "Q8IHT8", "name": "VCPKMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10695844", "map_id": "none", "name": "SUMOylation of BLM with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695825", "map_id": "Q8I2W7", "name": "BLM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0918600", "map_id": "PF3D7_0918600", "name": "4SUMO2,3-BLM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695841", "map_id": "Q8I2W7", "name": "4SUMO2,3-BLM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695934", "map_id": "none", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695924", "map_id": "Q8ILD6", "name": "XPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1432600", "map_id": "PF3D7_1432600", "name": "XPC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695932", "map_id": "none", "name": "SUMO1:XPC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILD6", "map_id": "Q8ILD6", "name": "XPC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695805", "map_id": "none", "name": "PIAS4 SUMOylates HERC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695789", "map_id": "none", "name": "Homologues of HERC2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IDD6", "map_id": "Q8IDD6", "name": "HERC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1356600", "map_id": "PF3D7_1356600", "name": "HERC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5L0", "map_id": "Q8I5L0", "name": "HERC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695802", "map_id": "none", "name": "SUMO1:HERC2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10695984", "map_id": "none", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695974", "map_id": "Q7K6A1", "name": "HDAC2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0925700", "map_id": "PF3D7_0925700", "name": "SUMO1-K444,K476-HDAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695982", "map_id": "none", "name": "SUMO1:HDAC2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q7K6A1", "map_id": "Q7K6A1", "name": "SUMO1-K444,K476-HDAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695911", "map_id": "none", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695909", "map_id": "none", "name": "SUMO1:HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10695894", "map_id": "none", "name": "SUMOylation of Histone H4 with SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695833", "map_id": "none", "name": "SUMO3:UBE2I", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10695891", "map_id": "Q8IIV2", "name": "SUMO3-HIST1H4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695957", "map_id": "none", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10693554", "map_id": "Q7K6A1", "name": "HDAC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695955", "map_id": "none", "name": "2SUMO1:HDAC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10695888", "map_id": "none", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695877", "map_id": "Q8IJV7", "name": "NOP58", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1008800", "map_id": "PF3D7_1008800", "name": "SUMO2-K467,K497-NOP58", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695886", "map_id": "none", "name": "2SUMO1:NOP58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IJV7", "map_id": "Q8IJV7", "name": "SUMO2-K467,K497-NOP58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695901", "map_id": "none", "name": "SUMOylation of NOP58 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695653", "map_id": "none", "name": "SUMO2:UBE2I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10695898", "map_id": "Q8IJV7", "name": "SUMO2-K467,K497-NOP58", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695715", "map_id": "none", "name": "SUMOylation of DAXX with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695018", "map_id": "C0H4S8", "name": "DAXX", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0807600", "map_id": "PF3D7_0807600", "name": "SUMO1-K630,K631-DAXX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695713", "map_id": "none", "name": "2SUMO1:DAXX", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "C0H4S8", "map_id": "C0H4S8", "name": "SUMO1-K630,K631-DAXX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695633", "map_id": "none", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695614", "map_id": "none", "name": "Homologues of DDX17", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I459", "map_id": "Q8I459", "name": "SUMO1-K50-DDX17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1445900", "map_id": "PF3D7_1445900", "name": "SUMO1-K50-DDX17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAR1", "map_id": "Q8IAR1", "name": "SUMO1-K50-DDX17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL13", "map_id": "Q8IL13", "name": "SUMO1-K50-DDX17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695630", "map_id": "none", "name": "SUMO1:DDX17", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10695664", "map_id": "none", "name": "PIAS1 SUMOylates DDX5 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695635", "map_id": "Q8IL13", "name": "DDX5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695656", "map_id": "Q8IL13", "name": "SUMO2-K53-DDX5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10695661", "map_id": "A0A5K1K9G1", "name": "PIAS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695694", "map_id": "none", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695681", "map_id": "C6KTB1", "name": "PARK7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0627500", "map_id": "PF3D7_0627500", "name": "Misfolded PARK7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695689", "map_id": "none", "name": "SUMO1:PARK7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "C6KTB1", "map_id": "C6KTB1", "name": "Misfolded PARK7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695691", "map_id": "A0A5K1K9G1", "name": "PIAS2-1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695645", "map_id": "none", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10695643", "map_id": "none", "name": "SUMO1:DDX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10690843", "map_id": "none", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690808", "map_id": "none", "name": "Dhp-K50-EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I603", "map_id": "Q8I603", "name": "Hyp-K50-EIF5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1204300", "map_id": "PF3D7_1204300", "name": "Hyp-K50-EIF5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690833", "map_id": "none", "name": "Hyp-K50-EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10690840", "map_id": "none", "name": "DOHH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I701", "map_id": "Q8I701", "name": "DOHH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1302600", "map_id": "PF3D7_1302600", "name": "DOHH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690826", "map_id": "none", "name": "DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690814", "map_id": "none", "name": "EIF5A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_204628", "map_id": "CHEBI:15725", "name": "1,3-diaminopropane", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690821", "map_id": "none", "name": "DHPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILW8", "map_id": "Q8ILW8", "name": "DHPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1412600", "map_id": "PF3D7_1412600", "name": "DHPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696630", "map_id": "none", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696605", "map_id": "Q8IKW5", "name": "nascent EEF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_353106", "map_id": "CHEBI:17509", "name": "MTAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10696592", "map_id": "Q8IKW5", "name": "aminocarboxypropyl EEF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10696622", "map_id": "none", "name": "DPH1:DPH2:DPH3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILV7", "map_id": "Q8ILV7", "name": "DPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1413800", "map_id": "PF3D7_1413800", "name": "DPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILG9", "map_id": "Q8ILG9", "name": "DPH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1429500", "map_id": "PF3D7_1429500", "name": "DPH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5N0", "map_id": "Q8I5N0", "name": "DPH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1217800", "map_id": "PF3D7_1217800", "name": "DPH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696628", "map_id": "Q8I473", "name": "DNAJC24", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0502800", "map_id": "PF3D7_0502800", "name": "DNAJC24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696603", "map_id": "none", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696595", "map_id": "Q8IKW5", "name": "Me-diphthine EEF2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10696600", "map_id": "Q8IJV5", "name": "DPH5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1009000", "map_id": "PF3D7_1009000", "name": "DPH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699358", "map_id": "none", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6788753", "map_id": "CHEBI:86019", "name": "S-FARN-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6788758", "map_id": "CHEBI:87167", "name": "S-FARN-CME", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699355", "map_id": "none", "name": "ICMT:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8I555", "map_id": "Q8I555", "name": "ICMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1236800", "map_id": "PF3D7_1236800", "name": "ICMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689522", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449229", "map_id": "CHEBI:15809", "name": "DOLP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855663", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_162872", "map_id": "CHEBI:16214", "name": "dolichyl phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855667", "map_id": "CHEBI:53058", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10689519", "map_id": "Q8I4V9", "name": "PIGV", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1247300", "map_id": "PF3D7_1247300", "name": "PIGV", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689506", "map_id": "none", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855656", "map_id": "CHEBI:53059", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10689503", "map_id": "Q8IDS3", "name": "PIGB", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_1341600", "map_id": "PF3D7_1341600", "name": "PIGB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689514", "map_id": "none", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8855657", "map_id": "CHEBI:15935", "name": "N-acetylglucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855661", "map_id": "CHEBI:24275", "name": "glucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10689511", "map_id": "C6KT83", "name": "PIGL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_0624700", "map_id": "PF3D7_0624700", "name": "PIGL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689498", "map_id": "none", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_8855666", "map_id": "CHEBI:52572", "name": "glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10689495", "map_id": "C6KSZ4", "name": "PIGW", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_0615300", "map_id": "PF3D7_0615300", "name": "PIGW", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692115", "map_id": "none", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_162756", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_449222", "map_id": "CHEBI:18278", "name": "GlcNAcDOLDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449293", "map_id": "CHEBI:18341", "name": "N,N'-DCDOLDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_110096", "map_id": "CHEBI:17659", "name": "UDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692112", "map_id": "none", "name": "ALG13:ALG14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8IAQ4", "map_id": "Q8IAQ4", "name": "ALG13(1-165)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0806400", "map_id": "PF3D7_0806400", "name": "ALG13(1-165)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O96196", "map_id": "O96196", "name": "ALG14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0211600", "map_id": "PF3D7_0211600", "name": "ALG14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692070", "map_id": "none", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449299", "map_id": "CHEBI:16214", "name": "DOLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10692067", "map_id": "O97321", "name": "DPAGT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_0321200", "map_id": "PF3D7_0321200", "name": "DPAGT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695754", "map_id": "none", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4419981", "map_id": "CHEBI:67132", "name": "pPNOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449221", "map_id": "CHEBI:16091", "name": "DCHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10692078", "map_id": "none", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_110094", "map_id": "CHEBI:17239", "name": "CDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10692075", "map_id": "B9ZSI8", "name": "DOLK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_0109850", "map_id": "PF3D7_0109850", "name": "DOLK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699345", "map_id": "none", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_162860", "map_id": "CHEBI:15820", "name": "GDP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6787618", "map_id": "CHEBI:16955", "name": "GDP-DHDMan", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699342", "map_id": "Q8IAX4", "name": "GMDS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0813800", "map_id": "PF3D7_0813800", "name": "GMDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699348", "map_id": "none", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787646", "map_id": "CHEBI:86476", "name": "GDP-KDGal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699334", "map_id": "none", "name": "TSTA3 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A143ZXB3", "map_id": "A0A143ZXB3", "name": "TSTA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1014000", "map_id": "PF3D7_1014000", "name": "TSTA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699337", "map_id": "none", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10692100", "map_id": "none", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532204", "map_id": "CHEBI:7125", "name": "AcGlcN1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692097", "map_id": "none", "name": "2xUAP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDQ3", "map_id": "Q8IDQ3", "name": "UAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1343600", "map_id": "PF3D7_1343600", "name": "UAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692127", "map_id": "none", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_449701", "map_id": "CHEBI:15873", "name": "GlcN6P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692124", "map_id": "none", "name": "GFPT1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJF3", "map_id": "Q8IJF3", "name": "GFPT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1025100", "map_id": "PF3D7_1025100", "name": "GFPT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692062", "map_id": "none", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_449703", "map_id": "CHEBI:15784", "name": "AcGlcN6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692059", "map_id": "Q8II63", "name": "PGM3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1130000", "map_id": "PF3D7_1130000", "name": "PGM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701400", "map_id": "none", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10701396", "map_id": "none", "name": "cis-Golgi cis SNARE bundle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10701398", "map_id": "none", "name": "cis-SNARE:3xSNAP:NSF hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10701278", "map_id": "none", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10701225", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10701276", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10701228", "map_id": "none", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10701223", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10692738", "map_id": "none", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10692672", "map_id": "none", "name": "Tn antigens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "Q8IKY8", "map_id": "Q8IKY8", "name": "Core 8 (MUC17)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1448500", "map_id": "PF3D7_1448500", "name": "Core 8 (MUC17)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A143ZYL5", "map_id": "A0A143ZYL5", "name": "Core 8 (MUC19)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1036900", "map_id": "PF3D7_1036900", "name": "Core 8 (MUC19)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_205687", "map_id": "CHEBI:17659", "name": "UDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10692736", "map_id": "none", "name": "Core 7 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10692704", "map_id": "none", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_914003", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10692702", "map_id": "none", "name": "Core 6 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10692694", "map_id": "none", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10692692", "map_id": "none", "name": "Core 8 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10692684", "map_id": "none", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10692682", "map_id": "none", "name": "Core 5 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10696147", "map_id": "none", "name": "POFUT2 transfers fucose to TSR domain-containing proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10696139", "map_id": "none", "name": "POFUT2 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "O97267", "map_id": "O97267", "name": "SPON1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0315200", "map_id": "PF3D7_0315200", "name": "SPON1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696118", "map_id": "none", "name": "O-fuc-proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10696144", "map_id": "Q8I360", "name": "POFUT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "PF3D7_0909200", "map_id": "PF3D7_0909200", "name": "POFUT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698145", "map_id": "none", "name": "USP21 deubiquitinates RIPK1,DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698138", "map_id": "none", "name": "USP21:PolyUb-RIPK1, PolyUb-DDX58", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILU9", "map_id": "Q8ILU9", "name": "USP21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1414700", "map_id": "PF3D7_1414700", "name": "USP21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDK6", "map_id": "Q8IDK6", "name": "PolyUb-RIPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1349300", "map_id": "PF3D7_1349300", "name": "PolyUb-RIPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL78", "map_id": "Q8IL78", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698142", "map_id": "none", "name": "USP21:RIPK1,DDX58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10698720", "map_id": "none", "name": "USP49 deubiquitinates H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10698715", "map_id": "none", "name": "USP49:Ub-histone H2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10698717", "map_id": "none", "name": "USP49:Histone H2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10698089", "map_id": "none", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698085", "map_id": "Q8I3J3", "name": "USP14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0527200", "map_id": "PF3D7_0527200", "name": "USP14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698087", "map_id": "none", "name": "ADRM1:26S proteasome:USP14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3J3", "map_id": "Q8I3J3", "name": "USP14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698681", "map_id": "none", "name": "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10698678", "map_id": "none", "name": "CYLD:K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689710", "map_id": "Q8IDK6", "name": "RIPK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10698126", "map_id": "none", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10698121", "map_id": "none", "name": "USP16,USP21:Ub-histone H2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10698123", "map_id": "none", "name": "USP16,USP22:Histone H2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10699197", "map_id": "none", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10698740", "map_id": "none", "name": "USP37:RUVLB1:PSMC5:PolyUb-CCNA1,PolyUb-CCNA2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IIU3", "map_id": "Q8IIU3", "name": "RUVBL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1106000", "map_id": "PF3D7_1106000", "name": "RUVBL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698744", "map_id": "none", "name": "USP37:RUVLB1:PSMC5:CCNA1,CCNA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10699194", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10698352", "map_id": "none", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10686745", "map_id": "Q8ID28", "name": "PSMD14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10699265", "map_id": "none", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10699261", "map_id": "Q8I607", "name": "UBE2D1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1203900", "map_id": "PF3D7_1203900", "name": "UBE2F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10699259", "map_id": "none", "name": "OTUB1,(OTUB2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILN4", "map_id": "Q8ILN4", "name": "OTUB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1421600", "map_id": "PF3D7_1421600", "name": "OTUB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10699263", "map_id": "none", "name": "OTUB1,(OTUB2):UBE2D1,ESR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I607", "map_id": "Q8I607", "name": "UBE2F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702033", "map_id": "none", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701967", "map_id": "none", "name": "Ub-Cys632-UBA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I5F9", "map_id": "Q8I5F9", "name": "UBA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1333200", "map_id": "PF3D7_1333200", "name": "UBA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701969", "map_id": "none", "name": "Ub-Cys632-UBA1:ubiquitin adenylate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702039", "map_id": "none", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693374", "map_id": "Q8I5F9", "name": "UBA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10701971", "map_id": "none", "name": "UBA1:ubiquitin adenylate", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10701991", "map_id": "none", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701965", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA1 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I2U3", "map_id": "Q8I2U3", "name": "UBE2G2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0921000.1", "map_id": "PF3D7_0921000.1", "name": "UBE2G2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IJ70", "map_id": "Q8IJ70", "name": "UBE2H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1033900", "map_id": "PF3D7_1033900", "name": "UBE2H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDD9", "map_id": "Q8IDD9", "name": "UBE2K", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1356300", "map_id": "PF3D7_1356300", "name": "UBE2K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701989", "map_id": "none", "name": "Ub:E2 (UBA1 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10701895", "map_id": "none", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701881", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA6 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10701879", "map_id": "none", "name": "Ub-Cys625-UBA6:ubiquitin adenylate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDZ6", "map_id": "Q8IDZ6", "name": "UBA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701883", "map_id": "none", "name": "UBA6:ubiquitin adenylate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10701893", "map_id": "none", "name": "Ub:E2 (UBA6 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702070", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10686680", "map_id": "Q7KQK2", "name": "RPS27A(1-76)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687728", "map_id": "Q7KQK2", "name": "RPS27A(77-156)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10702036", "map_id": "none", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10701963", "map_id": "none", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10701897", "map_id": "Q8I5F9", "name": "UBA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10701961", "map_id": "none", "name": "UBA1:ubiquitin adenylate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10702074", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702072", "map_id": "Q7KQK2", "name": "UBA52(1-128)", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688129", "map_id": "Q7KQK2", "name": "RPL40", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10702041", "map_id": "none", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10701993", "map_id": "none", "name": "Ub-Cys632-UBA1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10702030", "map_id": "none", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10701995", "map_id": "none", "name": "Ub-Cys632-UBA1:ubiquitin adenylate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10702028", "map_id": "none", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10702007", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA1 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O77397", "map_id": "O77397", "name": "UBE2U", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0812600", "map_id": "PF3D7_0812600", "name": "UBE2U", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAW2", "map_id": "Q8IAW2", "name": "UBE2U", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILW5", "map_id": "Q8ILW5", "name": "UBE2W", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1412900.1", "map_id": "PF3D7_1412900.1", "name": "UBE2W", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10702026", "map_id": "none", "name": "Ub:E2 (UBA1 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10702374", "map_id": "none", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10702344", "map_id": "none", "name": "Polyglutamylated microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10702371", "map_id": "none", "name": "TTLLs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJU8", "map_id": "Q8IJU8", "name": "TTLL13P", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1147200", "map_id": "PF3D7_1147200", "name": "TTLL13P", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IHP8", "map_id": "Q8IHP8", "name": "TTLL13P", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688265", "map_id": "none", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111628", "map_id": "CHEBI:15859", "name": "N-carb-L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76630", "map_id": "CHEBI:17025", "name": "(S)-DHO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688262", "map_id": "none", "name": "CAD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IEN3", "map_id": "Q8IEN3", "name": "CAD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1308200", "map_id": "PF3D7_1308200", "name": "CAD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688271", "map_id": "none", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111627", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111647", "map_id": "CHEBI:17672", "name": "CAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10688255", "map_id": "none", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73663", "map_id": "CHEBI:46245", "name": "CoQ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_76632", "map_id": "CHEBI:16742", "name": "ORO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76633", "map_id": "CHEBI:17976", "name": "QH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10688252", "map_id": "none", "name": "DHODH:FMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q08210", "map_id": "Q08210", "name": "DHODH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PFF0160c", "map_id": "PFF0160c", "name": "DHODH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688268", "map_id": "none", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10702131", "map_id": "none", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10702126", "map_id": "none", "name": "RAB7:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10702128", "map_id": "none", "name": "RAB7:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10702146", "map_id": "none", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10702141", "map_id": "none", "name": "RAB33:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10702143", "map_id": "none", "name": "RAB33:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10702113", "map_id": "none", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10702102", "map_id": "none", "name": "RAB7A:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10702104", "map_id": "none", "name": "RAB7A:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10702111", "map_id": "none", "name": "Homologues of TBC1D2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702850", "map_id": "none", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10702823", "map_id": "none", "name": "GGC-RAB7:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10702685", "map_id": "none", "name": "GDIs,CHMs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10702831", "map_id": "none", "name": "GGC-RAB7:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10702847", "map_id": "none", "name": "MON1:CCZ1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IIT1", "map_id": "Q8IIT1", "name": "CCZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1107200", "map_id": "PF3D7_1107200", "name": "CCZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IDH2", "map_id": "Q8IDH2", "name": "MON1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1352800", "map_id": "PF3D7_1352800", "name": "MON1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702761", "map_id": "none", "name": "RAB5 GEFs exchange GTP for GDP on RAB5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10702687", "map_id": "none", "name": "GGC-RAB5:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10702705", "map_id": "none", "name": "GGC-RAB5:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_10702758", "map_id": "none", "name": "RAB5 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILY5", "map_id": "Q8ILY5", "name": "RIN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1411000.2", "map_id": "PF3D7_1411000.2", "name": "RIN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A1B7", "map_id": "A0A144A1B7", "name": "RIN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IAZ5", "map_id": "Q8IAZ5", "name": "RIN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10702910", "map_id": "none", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane" }, { "id": "species_10702872", "map_id": "none", "name": "GGC-RAB1:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10702886", "map_id": "none", "name": "GGC-RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "species_10702907", "map_id": "none", "name": "TRAPPCs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I560", "map_id": "Q8I560", "name": "TRAPPC12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1236300", "map_id": "PF3D7_1236300", "name": "TRAPPC12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I481", "map_id": "Q8I481", "name": "TRAPPC13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0501900", "map_id": "PF3D7_0501900", "name": "TRAPPC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I451", "map_id": "Q8I451", "name": "TRAPPC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0505100", "map_id": "PF3D7_0505100", "name": "TRAPPC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689388", "map_id": "none", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10689380", "map_id": "none", "name": "Homologues of CYCS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693609", "map_id": "none", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_379721", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10693585", "map_id": "none", "name": "2 Iron:FXN:NFS1:ISD11:ISCU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IKT4", "map_id": "Q8IKT4", "name": "ISCU-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1454500", "map_id": "PF3D7_1454500", "name": "ISCU-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEK7", "map_id": "Q8IEK7", "name": "LYRM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1311000", "map_id": "PF3D7_1311000", "name": "LYRM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBI5", "map_id": "Q8IBI5", "name": "PXLP-K258-NFS1-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0727200", "map_id": "PF3D7_0727200", "name": "PXLP-K258-NFS1-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_379697", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10693600", "map_id": "none", "name": "FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33739", "map_id": "CHEBI:33739", "name": "CHEBI:33739", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693614", "map_id": "none", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10693612", "map_id": "none", "name": "FXN:ISD11:NFS1:ISCU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10693558", "map_id": "none", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1236719", "map_id": "CHEBI:16670", "name": "Exogenous soluble antigen", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8942986", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_983036", "map_id": "CHEBI:25676", "name": "precursor peptide fragment (>16 aa)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10703040", "map_id": "none", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983032", "map_id": "CHEBI:25676", "name": "oligopeptide fragment (8-16aa)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8955634", "map_id": "CHEBI:25676", "name": "oligopeptide fragment (3-7aa)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703037", "map_id": "Q8IJY3", "name": "THOP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1005700", "map_id": "PF3D7_1005700", "name": "THOP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693397", "map_id": "none", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693343", "map_id": "none", "name": "E2 Ubiquitin-conjugating enzyme", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10693394", "map_id": "none", "name": "E1 bound ubiquitin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10693392", "map_id": "none", "name": "Ubiquitin activating E1 enzymes", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693345", "map_id": "none", "name": "Ubiquitin:E2 conjugating enzymes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693403", "map_id": "none", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693351", "map_id": "none", "name": "E3:Ub:substrate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I1Q1", "map_id": "Q8I1Q1", "name": "HERC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0418600", "map_id": "PF3D7_0418600", "name": "HERC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A1E5", "map_id": "A0A144A1E5", "name": "FBXO9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1247000.2", "map_id": "PF3D7_1247000.2", "name": "FBXO9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A0T0", "map_id": "A0A144A0T0", "name": "FBXO9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K8W0", "map_id": "A0A5K1K8W0", "name": "FBXW7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1363400", "map_id": "PF3D7_1363400", "name": "FBXW7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KTE0", "map_id": "C6KTE0", "name": "FBXW9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0630500", "map_id": "PF3D7_0630500", "name": "FBXW9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3G9", "map_id": "Q8I3G9", "name": "RLIM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0529900", "map_id": "PF3D7_0529900", "name": "RLIM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A144A3J8", "map_id": "A0A144A3J8", "name": "UNKL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1468400", "map_id": "PF3D7_1468400", "name": "UNKL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1S9", "map_id": "Q8I1S9", "name": "LONRF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1123300", "map_id": "PF3D7_1123300", "name": "LONRF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IID0", "map_id": "Q8IID0", "name": "LONRF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4K6", "map_id": "C0H4K6", "name": "TRIP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0704600", "map_id": "PF3D7_0704600", "name": "TRIP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693368", "map_id": "none", "name": "E3:K48-polyubiquitinated substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693354", "map_id": "none", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10693347", "map_id": "none", "name": "Ag-substrate:E3:E2:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10693271", "map_id": "none", "name": "E3 ligases in proteasomal degradation", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693370", "map_id": "none", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983123", "map_id": "none", "name": "K48polyUb-antigenic substrate", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693400", "map_id": "none", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10693405", "map_id": "none", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983035", "map_id": "none", "name": "antigenic substrate", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693372", "map_id": "none", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10693366", "map_id": "none", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_983034", "map_id": "CHEBI:25676", "name": "oligopeptide fragment", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10693363", "map_id": "none", "name": "TAP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10690798", "map_id": "none", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10690796", "map_id": "none", "name": "SAR1B:GTP:SEC23:SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10694518", "map_id": "none", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2213225", "map_id": "none", "name": "unfolded antigen", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2213226", "map_id": "none", "name": "MHC class II epitopes", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10694515", "map_id": "none", "name": "Cathepsin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10698337", "map_id": "none", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10698333", "map_id": "none", "name": "RAD23", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10695861", "map_id": "none", "name": "Homologues of CETN2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IL07", "map_id": "Q8IL07", "name": "Misfolded CETN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1446600", "map_id": "PF3D7_1446600", "name": "Misfolded CETN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I272", "map_id": "Q8I272", "name": "Misfolded CETN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I714", "map_id": "Q8I714", "name": "Misfolded CETN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10698335", "map_id": "none", "name": "XPC:RAD23:CETN2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688851", "map_id": "none", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688847", "map_id": "Q8ID22", "name": "ERCC4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1368800", "map_id": "PF3D7_1368800", "name": "ERCC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688842", "map_id": "O96136", "name": "ERCC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0203300", "map_id": "PF3D7_0203300", "name": "ERCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688849", "map_id": "none", "name": "ERCC1:ERCC4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O96136", "map_id": "O96136", "name": "ERCC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ID22", "map_id": "Q8ID22", "name": "ERCC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688768", "map_id": "none", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688760", "map_id": "none", "name": "Capping complex (intermediate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IC20", "map_id": "Q8IC20", "name": "RNMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0705000", "map_id": "PF3D7_0705000", "name": "RNMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KSV4", "map_id": "C6KSV4", "name": "phospho-p-SUPT5H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0610900", "map_id": "PF3D7_0610900", "name": "phospho-p-SUPT5H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688765", "map_id": "none", "name": "Capping complex (GpppN..)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688774", "map_id": "none", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687534", "map_id": "A0A5K1K8X7", "name": "NCBP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10687529", "map_id": "Q8I1T2", "name": "NCBP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10687536", "map_id": "none", "name": "Cap Binding Complex (CBC)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688725", "map_id": "none", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688723", "map_id": "none", "name": "RNA Pol II with phosphorylated CTD: CE complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688756", "map_id": "none", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688749", "map_id": "none", "name": "Capping complex (initial)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10688753", "map_id": "none", "name": "Capping complex (hydrolyzed)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688772", "map_id": "none", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688770", "map_id": "none", "name": "Capping complex (with freed 5'- GMP)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688763", "map_id": "none", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113571", "map_id": "CHEBI:15996", "name": "GTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_111349", "map_id": "CHEBI:17552", "name": "GDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10688747", "map_id": "none", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688743", "map_id": "C6KSV4", "name": "phospho-p-SUPT5H", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10688737", "map_id": "Q8IC20", "name": "RNMT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10688745", "map_id": "none", "name": "CE:Pol II CTD:Spt5 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688776", "map_id": "none", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687606", "map_id": "none", "name": "RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687608", "map_id": "none", "name": "capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10688751", "map_id": "none", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_72084", "map_id": "none", "name": "nascent pre-mRNA transcript", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10695347", "map_id": "none", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10695322", "map_id": "none", "name": "HSP40:HSP70:ADP:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IL88", "map_id": "Q8IL88", "name": "DNAJA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1437900", "map_id": "PF3D7_1437900", "name": "DNAJA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695339", "map_id": "none", "name": "HSP90:HSP90", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10695331", "map_id": "Q8ILC1", "name": "STIP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF14_0324", "map_id": "PF14_0324", "name": "STIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10695318", "map_id": "none", "name": "HSP40s", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10695345", "map_id": "none", "name": "HSP90:STIP1:HSP70:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILC1", "map_id": "Q8ILC1", "name": "STIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695362", "map_id": "none", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10695358", "map_id": "none", "name": "HSP40:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10695360", "map_id": "none", "name": "HSP70:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10695320", "map_id": "none", "name": "HSP40:HSP70:ATP:nascent protein", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10696814", "map_id": "none", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10696808", "map_id": "none", "name": "HSP90:ATP:STIP1:HSP70:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10695325", "map_id": "none", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10703669", "map_id": "none", "name": "NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703008", "map_id": "none", "name": "KEAP1:CUL3:RBX1:NFE2L2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_9714134", "map_id": "none", "name": "NFE2L2 inducers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10703667", "map_id": "none", "name": "NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10695268", "map_id": "none", "name": "GPX7,8 catalyze peroxidation of P4HB (PDI)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10695241", "map_id": "none", "name": "Homologues of P4HB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "Q8I2V9", "map_id": "Q8I2V9", "name": "HC53,56-P4HB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1472600", "map_id": "PF3D7_1472600", "name": "HC53,56-P4HB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IKB2", "map_id": "Q8IKB2", "name": "HC53,56-P4HB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4Y6", "map_id": "C0H4Y6", "name": "HC53,56-P4HB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_3341383", "map_id": "CHEBI:16240", "name": "H2O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10695252", "map_id": "none", "name": "Homologues of HC53,56-P4HB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10695265", "map_id": "none", "name": "ERO1L:GPX7,8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "Q8IIC3", "map_id": "Q8IIC3", "name": "ERO1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1124000", "map_id": "PF3D7_1124000", "name": "ERO1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5T2", "map_id": "Q8I5T2", "name": "GPX8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10695227", "map_id": "none", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_3341308", "map_id": "CHEBI:18421", "name": "O2-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10689563", "map_id": "none", "name": "Cytochrome c (oxidised)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38574", "map_id": "CHEBI:38574", "name": "CHEBI:38574", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689561", "map_id": "none", "name": "Cytochrome c (reduced)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38573", "map_id": "CHEBI:38573", "name": "CHEBI:38573", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10698668", "map_id": "none", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696199", "map_id": "CHEBI:15883", "name": "GP4G", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5696194", "map_id": "CHEBI:17345", "name": "GMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10698665", "map_id": "C0H4F3", "name": "NUDT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_0520600", "map_id": "PF3D7_0520600", "name": "NUDT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690238", "map_id": "none", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196934", "map_id": "CHEBI:18385", "name": "THMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29480", "map_id": "CHEBI:58937", "name": "ThDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10690235", "map_id": "none", "name": "2xTPK1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H556", "map_id": "C0H556", "name": "TPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0924300", "map_id": "PF3D7_0924300", "name": "TPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690256", "map_id": "none", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690253", "map_id": "Q8IJP5", "name": "FLAD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1015000", "map_id": "PF3D7_1015000", "name": "FLAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690266", "map_id": "none", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196931", "map_id": "CHEBI:17015", "name": "RIB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690263", "map_id": "none", "name": "RFK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDB3", "map_id": "Q8IDB3", "name": "RFK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1359100", "map_id": "PF3D7_1359100", "name": "RFK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690356", "map_id": "none", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_198852", "map_id": "CHEBI:58539", "name": "DeHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_198827", "map_id": "CHEBI:58539", "name": "DeHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690353", "map_id": "none", "name": "SLC2A1,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10690379", "map_id": "none", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690365", "map_id": "none", "name": "CYB5A:heme", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_1497805", "map_id": "CHEBI:59513", "name": "Asc.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690363", "map_id": "none", "name": "CYB5A:ferriheme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "CHEBI:36144", "map_id": "CHEBI:36144", "name": "CHEBI:36144", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_198816", "map_id": "CHEBI:38290", "name": "AscH-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690376", "map_id": "none", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690373", "map_id": "none", "name": "CYB5R3:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10694965", "map_id": "none", "name": "LMBRD1 transports lysosomal Cbl to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3000239", "map_id": "CHEBI:28911", "name": "Cbl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_3000241", "map_id": "CHEBI:28911", "name": "Cbl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694962", "map_id": "C0H5F8", "name": "LMBRD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "PF3D7_1338000", "map_id": "PF3D7_1338000", "name": "LMBRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10693012", "map_id": "none", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692996", "map_id": "none", "name": "MOCS3:Zn2+ (red.)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ID54", "map_id": "Q8ID54", "name": "CysS452-MOCS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1365400", "map_id": "PF3D7_1365400", "name": "CysS452-MOCS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10693001", "map_id": "none", "name": "MOCS3-S-S(1-):Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10693009", "map_id": "none", "name": "PXLP-K258-NFS1-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10690435", "map_id": "none", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_111355", "map_id": "CHEBI:15635", "name": "THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690425", "map_id": "Q8IAU6", "name": "SLC25A32", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_0811100", "map_id": "PF3D7_0811100", "name": "SLC25A32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10700995", "map_id": "none", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6803257", "map_id": "CHEBI:63907", "name": "5-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200640", "map_id": "CHEBI:65049", "name": "5,10-methenyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10700992", "map_id": "Q8I4Y1", "name": "MTHFS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1245000", "map_id": "PF3D7_1245000", "name": "MTHFS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690433", "map_id": "none", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200739", "map_id": "CHEBI:60473", "name": "5,10-methylene-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690414", "map_id": "none", "name": "MTHFD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6KTE2", "map_id": "C6KTE2", "name": "MTHFD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0630700", "map_id": "PF3D7_0630700", "name": "MTHFD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690417", "map_id": "none", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10698693", "map_id": "none", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6801451", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5389850", "map_id": "CHEBI:15637", "name": "10-formyl-THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10698690", "map_id": "none", "name": "MTHFD1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10690437", "map_id": "none", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111353", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10700997", "map_id": "none", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10690420", "map_id": "none", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10700987", "map_id": "none", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6801458", "map_id": "CHEBI:15638", "name": "5,10-methenyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10700984", "map_id": "none", "name": "MTHFD2, D2L", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10701000", "map_id": "none", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10690431", "map_id": "none", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197969", "map_id": "CHEBI:28624", "name": "THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693026", "map_id": "none", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965053", "map_id": "CHEBI:16709", "name": "PDX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_964952", "map_id": "CHEBI:28803", "name": "PDXP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10693021", "map_id": "none", "name": "2xPDXK:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10693024", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_964945", "map_id": "CHEBI:16410", "name": "PXA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_965146", "map_id": "CHEBI:18335", "name": "PXAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693028", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965131", "map_id": "CHEBI:17310", "name": "PXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29390", "map_id": "CHEBI:18405", "name": "PXLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10688410", "map_id": "none", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10694172", "map_id": "none", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694168", "map_id": "none", "name": "ribosome:mRNA:polypeptide+signal", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10694166", "map_id": "none", "name": "Signal Recognition Particle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IKX4", "map_id": "Q8IKX4", "name": "SRP54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1450100", "map_id": "PF3D7_1450100", "name": "SRP54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KT56", "map_id": "C6KT56", "name": "SRP68", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0621900", "map_id": "PF3D7_0621900", "name": "SRP68", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8II00", "map_id": "Q8II00", "name": "SRP72", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1136400", "map_id": "PF3D7_1136400", "name": "SRP72", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5P4", "map_id": "Q8I5P4", "name": "SRP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1216300", "map_id": "PF3D7_1216300", "name": "SRP19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H4Q0", "map_id": "C0H4Q0", "name": "SRP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0729000", "map_id": "PF3D7_0729000", "name": "SRP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10694170", "map_id": "none", "name": "SRP:polypeptide+signal:ribosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10696497", "map_id": "none", "name": "MeSeOH is reduced to MeSeH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5357663", "map_id": "CHEBI:77062", "name": "MeSeOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5357669", "map_id": "CHEBI:64685", "name": "MeSeH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10696500", "map_id": "none", "name": "MeSeO2H is reduced to MeSeOH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5357694", "map_id": "CHEBI:77012", "name": "MeSeO2H", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10696797", "map_id": "none", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263232", "compartment_display": "ciliary base" }, { "id": "species_10696793", "map_id": "none", "name": "PKA tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10696795", "map_id": "none", "name": "PKA regulatory subunits:cAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10696785", "map_id": "none", "name": "Homologues of PRKACA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "reaction_10687497", "map_id": "none", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687494", "map_id": "none", "name": "PPA1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O77392", "map_id": "O77392", "name": "PPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0316300.2", "map_id": "PF3D7_0316300.2", "name": "PPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C0H477", "map_id": "C0H477", "name": "PPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692143", "map_id": "none", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10692140", "map_id": "none", "name": "PPA2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10696800", "map_id": "none", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_975599", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10696902", "map_id": "none", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_5623644", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5623648", "map_id": "CHEBI:17898", "name": "atRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_163953", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5623650", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5623649", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10696899", "map_id": "C6KT97", "name": "RDH13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "PF3D7_0626100", "map_id": "PF3D7_0626100", "name": "RDH13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690305", "map_id": "none", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10690301", "map_id": "Q7KQK7", "name": "phospho-p-T218,Y220-MAPK7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690303", "map_id": "Q7KQK7", "name": "phospho-p-T218,Y220-MAPK7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10701024", "map_id": "none", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701020", "map_id": "none", "name": "Homologues of SFN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H4V6", "map_id": "C0H4V6", "name": "SFN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1362100", "map_id": "PF3D7_1362100", "name": "SFN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K948", "map_id": "A0A5K1K948", "name": "SFN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701022", "map_id": "none", "name": "SFN Dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689362", "map_id": "none", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689307", "map_id": "none", "name": "DSIF complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IJA5", "map_id": "Q8IJA5", "name": "SUPT4H1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1030000", "map_id": "PF3D7_1030000", "name": "SUPT4H1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689316", "map_id": "none", "name": "RNA Pol II (hypophosphorylated):capped pre-mRNA complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IJR8", "map_id": "Q8IJR8", "name": "CTDP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1012700", "map_id": "PF3D7_1012700", "name": "CTDP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689318", "map_id": "none", "name": "RNA Pol II (hypophosphorylated) complex bound to DSIF protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689339", "map_id": "none", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689314", "map_id": "Q8IJR8", "name": "CTDP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694275", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023929", "map_id": "CHEBI:17401", "name": "IP6", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023940", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10694192", "map_id": "none", "name": "IP6K1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I3W0", "map_id": "Q8I3W0", "name": "IP6K1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1316100", "map_id": "PF3D7_1316100", "name": "IP6K1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEF3", "map_id": "Q8IEF3", "name": "IP6K1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694195", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023932", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023931", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694341", "map_id": "none", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023922", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023948", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694335", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023941", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694254", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023901", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10694213", "map_id": "none", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114520", "map_id": "CHEBI:16595", "name": "I(1,4,5)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629739", "map_id": "CHEBI:17816", "name": "I(1,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694210", "map_id": "none", "name": "INPP5(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694251", "map_id": "none", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629756", "map_id": "CHEBI:4170", "name": "Glc6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629731", "map_id": "CHEBI:18169", "name": "I3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694248", "map_id": "none", "name": "ISYNA1:NAD+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3Y8", "map_id": "Q8I3Y8", "name": "ISYNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0511800", "map_id": "PF3D7_0511800", "name": "ISYNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694329", "map_id": "none", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694281", "map_id": "none", "name": "Homologues of INPP5B(321-993)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10694338", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629770", "map_id": "CHEBI:17401", "name": "IP6", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629765", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694205", "map_id": "none", "name": "IP6K1/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10694208", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629759", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694272", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629740", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629732", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694298", "map_id": "none", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694263", "map_id": "none", "name": "PPIP5K1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILG1", "map_id": "Q8ILG1", "name": "PPIP5K2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1430300", "map_id": "PF3D7_1430300", "name": "PPIP5K2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694266", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10694269", "map_id": "none", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629736", "map_id": "CHEBI:62926", "name": "1-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629738", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694332", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994141", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629755", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694241", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694238", "map_id": "none", "name": "PLCbz", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJR0", "map_id": "Q8IJR0", "name": "PLCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1013500", "map_id": "PF3D7_1013500", "name": "PLCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694288", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_994170", "map_id": "CHEBI:16783", "name": "I(1,3,4,5)P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_994123", "map_id": "CHEBI:18228", "name": "I(1,3,4)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694285", "map_id": "none", "name": "Inositol polyphosphate 5-phosphatase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10694295", "map_id": "none", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2023856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10694292", "map_id": "none", "name": "PLCD4:3xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10694326", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10694323", "map_id": "none", "name": "PLCdegh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10694301", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10701576", "map_id": "none", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701570", "map_id": "none", "name": "Unfolded G-protein beta subunit:CCT/TRiC:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H5I7", "map_id": "C0H5I7", "name": "CCT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1357800", "map_id": "PF3D7_1357800", "name": "CCT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97282", "map_id": "O97282", "name": "CCT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0320300", "map_id": "PF3D7_0320300", "name": "CCT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77323", "map_id": "O77323", "name": "CCT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PFC0350c", "map_id": "PFC0350c", "name": "CCT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6KST5", "map_id": "C6KST5", "name": "CCT6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0608700", "map_id": "PF3D7_0608700", "name": "CCT6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8II43", "map_id": "Q8II43", "name": "TCP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1132200", "map_id": "PF3D7_1132200", "name": "TCP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5C4", "map_id": "Q8I5C4", "name": "CCT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1229500", "map_id": "PF3D7_1229500", "name": "CCT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701574", "map_id": "none", "name": "Partially folded G-protein beta subunit:CCT/TRiC:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10701580", "map_id": "none", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10701578", "map_id": "none", "name": "Unfolded G-protein beta subunit:CCT/TRiC:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10701763", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_2022884", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_8851233", "map_id": "none", "name": "UTP,GTP,CTP,dTTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_8851224", "map_id": "none", "name": "UDP,GDP,CDP,dTDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "CHEBI:18075", "map_id": "CHEBI:18075", "name": "CHEBI:18075", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8851226", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10701757", "map_id": "none", "name": "NTPDase4:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q8IE96", "map_id": "Q8IE96", "name": "ENTPD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1322000", "map_id": "PF3D7_1322000", "name": "ENTPD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701760", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851227", "map_id": "none", "name": "UMP,GMP,CMP,dTMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_109366", "map_id": "CHEBI:17013", "name": "TMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10701792", "map_id": "none", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870906", "map_id": "CHEBI:16862", "name": "NDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8870962", "map_id": "CHEBI:26558", "name": "NMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10701740", "map_id": "none", "name": "NTPDase2:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10701750", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870907", "map_id": "CHEBI:17326", "name": "NTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10701747", "map_id": "none", "name": "NTPDase3:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10701733", "map_id": "none", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10701730", "map_id": "none", "name": "NTPDase1:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10701780", "map_id": "none", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8851462", "map_id": "none", "name": "CDP,GDP,IDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17808", "map_id": "CHEBI:17808", "name": "CHEBI:17808", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8851461", "map_id": "none", "name": "CMP,GMP,IMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10701777", "map_id": "none", "name": "NTPDase6:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q8ILE7", "map_id": "Q8ILE7", "name": "ENTPD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1431800", "map_id": "PF3D7_1431800", "name": "ENTPD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10701787", "map_id": "none", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen" }, { "id": "species_8851517", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_8851509", "map_id": "none", "name": "CTP,GTP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_8851513", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_8851518", "map_id": "none", "name": "CDP,GDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_10701784", "map_id": "none", "name": "NTPDase7:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10701753", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10701736", "map_id": "none", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10701743", "map_id": "none", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936166", "map_id": "none", "name": "ATP,GTP,CTP,ITP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_2509836", "map_id": "CHEBI:16039", "name": "ITP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8851092", "map_id": "none", "name": "ADP,GDP,CDP,IDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10701773", "map_id": "none", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936165", "map_id": "none", "name": "ADP,GDP,CDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851369", "map_id": "none", "name": "AMP,GMP,CMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10701770", "map_id": "none", "name": "NPTDase5:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10701789", "map_id": "none", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10696804", "map_id": "none", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10691235", "map_id": "C0H553", "name": "NOS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691203", "map_id": "A0A5K1K8L6", "name": "ATP2B4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10696802", "map_id": "none", "name": "ATP2B4:NOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10688530", "map_id": "none", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "reaction_10692234", "map_id": "none", "name": "AUF1:mRNA complex is destroyed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692232", "map_id": "none", "name": "Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I2Y5", "map_id": "Q8I2Y5", "name": "Ub-HNRNPD-4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0916700", "map_id": "PF3D7_0916700", "name": "Ub-HNRNPD-4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692221", "map_id": "none", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_450444", "map_id": "none", "name": "mRNA Transcript Targeted by AUF1(hnRNP D0)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10692215", "map_id": "none", "name": "AUF1 Dimer (isoform p37 or p40)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692219", "map_id": "none", "name": "AUF1 Tetramer: Destabilized mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10701160", "map_id": "none", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10701156", "map_id": "none", "name": "Casein kinase II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10689351", "map_id": "none", "name": "FACT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IL56", "map_id": "Q8IL56", "name": "SSRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1441400", "map_id": "PF3D7_1441400", "name": "SSRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3T4", "map_id": "Q8I3T4", "name": "SUPT16H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0517400", "map_id": "PF3D7_0517400", "name": "SUPT16H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701158", "map_id": "none", "name": "CK2:FACT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10700957", "map_id": "none", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10700953", "map_id": "C6KSM5", "name": "RABGGTB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10700948", "map_id": "Q8IL46", "name": "RABGGTA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10700955", "map_id": "none", "name": "RGGT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10701682", "map_id": "none", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692652", "map_id": "Q8I5W0", "name": "phospho-p-Y700,Y731,Y774-CBL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1208800", "map_id": "PF3D7_1208800", "name": "CBLB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10701679", "map_id": "Q8I5W0", "name": "phospho-PolyUb,p-Y700,Y731,Y774-CBL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694665", "map_id": "none", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10694663", "map_id": "none", "name": "PDPK1:PIP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10692274", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_374064", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_374061", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113585", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10692271", "map_id": "none", "name": "ARG2 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10687249", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29498", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687246", "map_id": "none", "name": "ARG1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10690983", "map_id": "none", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353113", "map_id": "CHEBI:15625", "name": "dc-AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29610", "map_id": "CHEBI:17148", "name": "Putrescine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690980", "map_id": "Q8II73", "name": "SRM", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1129000", "map_id": "PF3D7_1129000", "name": "SRM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687304", "map_id": "none", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10687301", "map_id": "Q8IJ77", "name": "PXLP-K69-ODC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10690975", "map_id": "none", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353555", "map_id": "CHEBI:17927", "name": "NASPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690970", "map_id": "C0H4M8", "name": "SAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0713900", "map_id": "PF3D7_0713900", "name": "SAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690973", "map_id": "none", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353575", "map_id": "CHEBI:17312", "name": "NASPN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10687283", "map_id": "none", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_31339", "map_id": "CHEBI:17232", "name": "L-Glu5S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687280", "map_id": "none", "name": "OAT hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q6LFH8", "map_id": "Q6LFH8", "name": "OAT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PFF0435w", "map_id": "PFF0435w", "name": "OAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699301", "map_id": "none", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35305", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10699298", "map_id": "none", "name": "PYCRL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IDC6", "map_id": "Q8IDC6", "name": "PYCR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1357900", "map_id": "PF3D7_1357900", "name": "PYCR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699294", "map_id": "none", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113590", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10699291", "map_id": "none", "name": "PYCR2 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10687293", "map_id": "none", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10687290", "map_id": "none", "name": "PYCR1 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10690407", "map_id": "none", "name": "Creatine transport across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_200381", "map_id": "CHEBI:16919", "name": "CRET", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_29916", "map_id": "CHEBI:16919", "name": "CRET", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690404", "map_id": "none", "name": "SLC6A8-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10699868", "map_id": "none", "name": "SLC44A1 transports Cho from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10699865", "map_id": "Q8ILE6", "name": "SLC44A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10687346", "map_id": "none", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70836", "map_id": "CHEBI:15476", "name": "2MACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70843", "map_id": "CHEBI:15539", "name": "PROP-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10698395", "map_id": "none", "name": "PPM1K dephosphorylates p-BCKDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10698385", "map_id": "none", "name": "p-BCKDH", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O97227", "map_id": "O97227", "name": "DBT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0303700", "map_id": "PF3D7_0303700", "name": "DBT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEJ6", "map_id": "Q8IEJ6", "name": "BCKDHA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1312600", "map_id": "PF3D7_1312600", "name": "BCKDHA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I0X1", "map_id": "Q8I0X1", "name": "phospho-p-S292-BCKDHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0504600", "map_id": "PF3D7_0504600", "name": "phospho-p-S292-BCKDHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10687333", "map_id": "none", "name": "lipo-BCKDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10698392", "map_id": "none", "name": "PPM1K:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "C0H4T6", "map_id": "C0H4T6", "name": "PPM1K", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0810300", "map_id": "PF3D7_0810300", "name": "PPM1K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687354", "map_id": "none", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_71847", "map_id": "CHEBI:28259", "name": "bHIB-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_573404", "map_id": "CHEBI:11805", "name": "bHIBA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687351", "map_id": "Q8I523", "name": "HIBCH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1240000", "map_id": "PF3D7_1240000", "name": "HIBCH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687336", "map_id": "none", "name": "BCKDH transfers CoA group from CoA-SH to BCAAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_508181", "map_id": "none", "name": "KIC, KMVA, KIV", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:16530", "map_id": "CHEBI:16530", "name": "CHEBI:16530", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28654", "map_id": "CHEBI:28654", "name": "CHEBI:28654", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17865", "map_id": "CHEBI:17865", "name": "CHEBI:17865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_508261", "map_id": "none", "name": "BCAA-CoAs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:15479", "map_id": "CHEBI:15479", "name": "CHEBI:15479", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15487", "map_id": "CHEBI:15487", "name": "CHEBI:15487", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15477", "map_id": "CHEBI:15477", "name": "CHEBI:15477", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699863", "map_id": "none", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10699853", "map_id": "Q8II35", "name": "octanoyl-K107-GCSH", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6793610", "map_id": "CHEBI:26833", "name": "S", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6793613", "map_id": "CHEBI:17319", "name": "5dAde", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10699860", "map_id": "none", "name": "LIAS:2(4Fe-4S)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IDQ0", "map_id": "Q8IDQ0", "name": "lipA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MAL13P1.220", "map_id": "MAL13P1.220", "name": "lipA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:49883", "map_id": "CHEBI:49883", "name": "CHEBI:49883", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699850", "map_id": "none", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10699840", "map_id": "none", "name": "DHs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I6S5", "map_id": "Q8I6S5", "name": "OGDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0820700", "map_id": "PF3D7_0820700", "name": "OGDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17460", "map_id": "CHEBI:17460", "name": "CHEBI:17460", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IEA6", "map_id": "Q8IEA6", "name": "Lipo-K110-DLST", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1320800", "map_id": "PF3D7_1320800", "name": "Lipo-K110-DLST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10699842", "map_id": "none", "name": "lipoylated DHs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10698403", "map_id": "Q8II35", "name": "GCSH", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10699847", "map_id": "Q8IEG9", "name": "LIPT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "PF3D7_1314600", "map_id": "PF3D7_1314600", "name": "LIPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699304", "map_id": "none", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784236", "map_id": "CHEBI:32812", "name": "4-OH-L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6784229", "map_id": "CHEBI:17742", "name": "HOG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10687396", "map_id": "none", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70951", "map_id": "CHEBI:15753", "name": "aKADA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70955", "map_id": "CHEBI:15524", "name": "GL-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687393", "map_id": "none", "name": "lipo-aKGDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10687406", "map_id": "none", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_71112", "map_id": "CHEBI:15374", "name": "4aOH-BH4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71129", "map_id": "CHEBI:20680", "name": "qDHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687403", "map_id": "none", "name": "PCBD1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6S3E6", "map_id": "C6S3E6", "name": "PCBD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1108300", "map_id": "PF3D7_1108300", "name": "PCBD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690627", "map_id": "none", "name": "eNOS:NOSIP translocation from caveolae to intracellular compartments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10690591", "map_id": "none", "name": "eNOS:NOSIP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "C0H4E6", "map_id": "C0H4E6", "name": "NOSIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0518000", "map_id": "PF3D7_0518000", "name": "NOSIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10690625", "map_id": "none", "name": "eNOS:NOSIP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10690593", "map_id": "none", "name": "eNOS binds NOSIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690589", "map_id": "C0H4E6", "name": "NOSIP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690485", "map_id": "none", "name": "palmitoylated, myristoylated eNOS dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10696674", "map_id": "none", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358610", "map_id": "none", "name": "DNA containing single strand nick (5' phosphate, 3' hydroxyl)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_109966", "map_id": "none", "name": "Repaired double-stranded DNA", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10696707", "map_id": "none", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696653", "map_id": "Q8I447", "name": "MSH6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0505500", "map_id": "PF3D7_0505500", "name": "MSH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696648", "map_id": "Q8ILI9", "name": "MSH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1427500", "map_id": "PF3D7_1427500", "name": "MSH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696668", "map_id": "none", "name": "MSH2:MSH6:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8ILI9", "map_id": "Q8ILI9", "name": "MSH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I447", "map_id": "Q8I447", "name": "MSH6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696672", "map_id": "none", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358514", "map_id": "none", "name": "DNA containing mismatch or 1-2 base IDL", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10696670", "map_id": "none", "name": "MSH2:MSH6:ADP:DNA containing 1-2 base mismatch", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10696709", "map_id": "none", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696636", "map_id": "Q8IIJ0", "name": "MLH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_1117800", "map_id": "PF3D7_1117800", "name": "MLH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696641", "map_id": "Q8IBJ3", "name": "PMS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0726300", "map_id": "PF3D7_0726300", "name": "PMS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696643", "map_id": "none", "name": "MLH1:PMS2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IBJ3", "map_id": "Q8IBJ3", "name": "PMS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIJ0", "map_id": "Q8IIJ0", "name": "MLH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696661", "map_id": "none", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696657", "map_id": "none", "name": "MSH2:MSH6:ATP:DNA containing 1-2 base mismatch", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10696659", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10696683", "map_id": "none", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10696679", "map_id": "Q8IBK1", "name": "EXO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0725000", "map_id": "PF3D7_0725000", "name": "EXO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696663", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10696681", "map_id": "none", "name": "EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8IBK1", "map_id": "Q8IBK1", "name": "EXO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10696666", "map_id": "none", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10696685", "map_id": "none", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10690965", "map_id": "none", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10690953", "map_id": "none", "name": "Arf1-GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10690957", "map_id": "none", "name": "Arf1-GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10696403", "map_id": "none", "name": "AP4 transports APP from trans-Golgi network to endosome lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171907", "compartment_display": "endosome lumen" }, { "id": "species_10696386", "map_id": "none", "name": "AP4:APP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "Q8IIH2", "map_id": "Q8IIH2", "name": "AP4M1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1119500", "map_id": "PF3D7_1119500", "name": "AP4M1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IBF8", "map_id": "Q8IBF8", "name": "AP4B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0730200", "map_id": "PF3D7_0730200", "name": "AP4B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IFN5", "map_id": "Q8IFN5", "name": "AP4S1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0423100", "map_id": "PF3D7_0423100", "name": "AP4S1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3A8", "map_id": "Q8I3A8", "name": "AP4E1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0904100", "map_id": "PF3D7_0904100", "name": "AP4E1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10696400", "map_id": "none", "name": "AP4:APP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "true" }, { "id": "reaction_10689478", "map_id": "none", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689469", "map_id": "none", "name": "eEF1B complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O97319", "map_id": "O97319", "name": "EEF1B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0913200", "map_id": "PF3D7_0913200", "name": "EEF1B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I320", "map_id": "Q8I320", "name": "EEF1B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5K1K967", "map_id": "A0A5K1K967", "name": "EEF1G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1338300", "map_id": "PF3D7_1338300", "name": "EEF1G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689473", "map_id": "none", "name": "eEF1A:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689444", "map_id": "none", "name": "eEF1A:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689475", "map_id": "none", "name": "eEF1B:GDP exchange complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689471", "map_id": "none", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689467", "map_id": "A0A5K1K967", "name": "EEF1G", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689462", "map_id": "none", "name": "Homologues of EEF1D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10689456", "map_id": "none", "name": "Homologues of EEF1B2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689366", "map_id": "none", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10688732", "map_id": "none", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688729", "map_id": "none", "name": "Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10689360", "map_id": "none", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689305", "map_id": "Q8IJA5", "name": "SUPT4H1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689364", "map_id": "none", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689336", "map_id": "none", "name": "DSIF:NELF:early elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "C6KSQ9", "map_id": "C6KSQ9", "name": "NELFE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0606100", "map_id": "PF3D7_0606100", "name": "NELFE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9U0K9", "map_id": "Q9U0K9", "name": "NELFCD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0407700", "map_id": "PF3D7_0407700", "name": "NELFCD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689353", "map_id": "none", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10689349", "map_id": "Q8I3T4", "name": "SUPT16H", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10689344", "map_id": "Q8IL56", "name": "SSRP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10689133", "map_id": "none", "name": "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10697443", "map_id": "none", "name": "LC3 de-lipidation by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697357", "map_id": "none", "name": "LC3:PE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "Q8IJK2", "map_id": "Q8IJK2", "name": "MAP1LC3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1019900", "map_id": "PF3D7_1019900", "name": "MAP1LC3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5681998", "map_id": "CHEBI:16038", "name": "PE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "species_10697347", "map_id": "none", "name": "LC3 family", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10697404", "map_id": "none", "name": "ATG4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILS3", "map_id": "Q8ILS3", "name": "ATG4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1417300", "map_id": "PF3D7_1417300", "name": "ATG4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10697409", "map_id": "none", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697363", "map_id": "none", "name": "ATG7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10697374", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697457", "map_id": "none", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10697455", "map_id": "none", "name": "LC3:PE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "reaction_10703360", "map_id": "none", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697365", "map_id": "none", "name": "ATG12:ATG7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C6S3K2", "map_id": "C6S3K2", "name": "ATG12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1470000", "map_id": "PF3D7_1470000", "name": "ATG12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697459", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697367", "map_id": "none", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697361", "map_id": "C6S3K2", "name": "ATG12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10697463", "map_id": "none", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697378", "map_id": "none", "name": "LC3:CysO263-ATG3:ATG7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H519", "map_id": "C0H519", "name": "ATG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0905700.2", "map_id": "PF3D7_0905700.2", "name": "ATG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10697355", "map_id": "none", "name": "CysO263-ATG3:LC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697461", "map_id": "none", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697359", "map_id": "C0H519", "name": "ATG3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10697376", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7:ATG3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10697381", "map_id": "none", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10697407", "map_id": "none", "name": "LC3 is cleaved by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10697391", "map_id": "none", "name": "LC3 family precursors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703521", "map_id": "none", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703517", "map_id": "none", "name": "Misfolded Proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10703502", "map_id": "none", "name": "Ub:UBE2N:UBE2V1:PRKN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I3J4", "map_id": "Q8I3J4", "name": "UBE2N", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0527100", "map_id": "PF3D7_0527100", "name": "UBE2N", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97241", "map_id": "O97241", "name": "UBE2V2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0305700", "map_id": "PF3D7_0305700", "name": "UBE2V2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10703519", "map_id": "none", "name": "Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703504", "map_id": "none", "name": "Parkin binds Ub:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703500", "map_id": "none", "name": "Ub:UBE2N:UBE2V1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703543", "map_id": "none", "name": "PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703541", "map_id": "none", "name": "PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10703539", "map_id": "none", "name": "PolyUb-Misfolded Proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10703523", "map_id": "none", "name": "UBE2N:UBE2V1:PRKN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703563", "map_id": "none", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10703561", "map_id": "none", "name": "Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10703565", "map_id": "none", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10703283", "map_id": "none", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787326", "map_id": "CHEBI:11563", "name": "dR1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6787328", "map_id": "CHEBI:16132", "name": "dR5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687116", "map_id": "none", "name": "PGM2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10687426", "map_id": "none", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29732", "map_id": "CHEBI:17363", "name": "RU5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29790", "map_id": "CHEBI:57737", "name": "XY5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10687423", "map_id": "none", "name": "RPE:Fe2+ dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I5L3", "map_id": "Q8I5L3", "name": "RPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1219900", "map_id": "PF3D7_1219900", "name": "RPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699327", "map_id": "none", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10690381", "map_id": "none", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10697188", "map_id": "none", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5661264", "map_id": "CHEBI:15748", "name": "D-glucuronate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5661268", "map_id": "CHEBI:13115", "name": "L-gulonate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10692240", "map_id": "none", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10692236", "map_id": "Q8IAZ3", "name": "ELAVL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_450613", "map_id": "none", "name": "mRNA Transcript Targeted by HuR with Unknown Phosphorylation", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10692238", "map_id": "none", "name": "HuR with Unknown Phosphorylation: mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10692472", "map_id": "none", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_450605", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318.", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10692247", "map_id": "Q8IAZ3", "name": "phospho-p-S158,S221-ELAVL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10692470", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine158:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10692476", "map_id": "none", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10692244", "map_id": "Q8IAZ3", "name": "phospho-p-S221,S318-ELAVL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_517622", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10692474", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine318:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10697334", "map_id": "none", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5687536", "map_id": "CHEBI:85309", "name": "isoAsp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5687529", "map_id": "CHEBI:31882", "name": "MetAsp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10697331", "map_id": "A0A144A3E6", "name": "PCMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_1432700", "map_id": "PF3D7_1432700", "name": "PCMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694769", "map_id": "none", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509848", "map_id": "CHEBI:10049", "name": "XTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694763", "map_id": "none", "name": "ITPA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IBP3", "map_id": "Q8IBP3", "name": "ITPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MAL7P1.110", "map_id": "MAL7P1.110", "name": "ITPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694772", "map_id": "none", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509835", "map_id": "CHEBI:28807", "name": "dITP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109330", "map_id": "CHEBI:28806", "name": "dIMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10694766", "map_id": "none", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10702430", "map_id": "none", "name": "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_8866574", "map_id": "CHEBI:61560", "name": "dNTP(4-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_8866608", "map_id": "CHEBI:18274", "name": "2'-deoxynucleoside", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_8866567", "map_id": "CHEBI:18036", "name": "PPPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10702427", "map_id": "none", "name": "SAMHD1:Zn2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I533", "map_id": "Q8I533", "name": "SAMHD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1239000", "map_id": "PF3D7_1239000", "name": "SAMHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699367", "map_id": "none", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6788802", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:15918", "map_id": "CHEBI:15918", "name": "CHEBI:15918", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6788801", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:16174", "map_id": "CHEBI:16174", "name": "CHEBI:16174", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28846", "map_id": "CHEBI:28846", "name": "CHEBI:28846", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10699364", "map_id": "none", "name": "Homologues of AK4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IJV6", "map_id": "Q8IJV6", "name": "AK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I1T1", "map_id": "Q8I1T1", "name": "AK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0415600", "map_id": "PF3D7_0415600", "name": "AK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688358", "map_id": "none", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500071", "map_id": "none", "name": "(d)GMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16192", "map_id": "CHEBI:16192", "name": "CHEBI:16192", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500077", "map_id": "none", "name": "(d)GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28862", "map_id": "CHEBI:28862", "name": "CHEBI:28862", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10688355", "map_id": "Q8I2M1", "name": "GUK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0928900", "map_id": "PF3D7_0928900", "name": "GUK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10699375", "map_id": "none", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6788813", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_6788807", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10699372", "map_id": "Q8I236", "name": "AK6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "PF3D7_0110900", "map_id": "PF3D7_0110900", "name": "AK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688302", "map_id": "none", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109382", "map_id": "CHEBI:17622", "name": "dUMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73604", "map_id": "CHEBI:15633", "name": "DHF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10688299", "map_id": "none", "name": "TS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I1R6", "map_id": "Q8I1R6", "name": "TYMS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0417200", "map_id": "PF3D7_0417200", "name": "TYMS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692407", "map_id": "none", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_482807", "map_id": "none", "name": "(d)NTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_500739", "map_id": "CHEBI:17625", "name": "dUTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_482803", "map_id": "none", "name": "(d)NDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:28850", "map_id": "CHEBI:28850", "name": "CHEBI:28850", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10692402", "map_id": "none", "name": "NME4 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "C6KSQ4", "map_id": "C6KSQ4", "name": "NME1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0605600", "map_id": "PF3D7_0605600", "name": "NME1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689211", "map_id": "none", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689189", "map_id": "Q9NLB2", "name": "2xHC-GLRX", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "PF3D7_0306300", "map_id": "PF3D7_0306300", "name": "GLRX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10689186", "map_id": "Q9NLB2", "name": "GLRX", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10688312", "map_id": "none", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_499997", "map_id": "none", "name": "dUMP, TMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500742", "map_id": "CHEBI:17622", "name": "dUMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_499999", "map_id": "none", "name": "dUDP, TDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688309", "map_id": "none", "name": "DTYMK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I4S1", "map_id": "Q8I4S1", "name": "DTYMK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1251300", "map_id": "PF3D7_1251300", "name": "DTYMK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689208", "map_id": "none", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8866401", "map_id": "CHEBI:57930", "name": "NDP(3-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8866399", "map_id": "CHEBI:73316", "name": "dNDP(3-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10689205", "map_id": "none", "name": "RNR (M1M2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IM38", "map_id": "Q8IM38", "name": "RRM2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1405600", "map_id": "PF3D7_1405600", "name": "RRM2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL94", "map_id": "Q8IL94", "name": "RRM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1437200", "map_id": "PF3D7_1437200", "name": "RRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688895", "map_id": "none", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788778", "map_id": "none", "name": "(d)NMPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_6788782", "map_id": "none", "name": "(d)NDPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688890", "map_id": "none", "name": "AK5,7,8,9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8I231", "map_id": "Q8I231", "name": "AK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0816900", "map_id": "PF3D7_0816900", "name": "AK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IB06", "map_id": "Q8IB06", "name": "AK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10689214", "map_id": "none", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10688893", "map_id": "none", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10701181", "map_id": "none", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6806885", "map_id": "CHEBI:16862", "name": "NDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6806881", "map_id": "CHEBI:17326", "name": "NTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10701178", "map_id": "none", "name": "NME1:NME3 heterohexamer, NME2P1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10692419", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10692416", "map_id": "none", "name": "CTPS2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8ILZ3", "map_id": "Q8ILZ3", "name": "CTPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1410200", "map_id": "PF3D7_1410200", "name": "CTPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688897", "map_id": "none", "name": "(d)ADP + ADP <=> (d)AMP + ATP (AK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500087", "map_id": "none", "name": "(d)ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500088", "map_id": "none", "name": "(d)AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10688385", "map_id": "Q8I231", "name": "AK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10688906", "map_id": "none", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688903", "map_id": "none", "name": "Homologues of AK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "reaction_10692362", "map_id": "none", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_482625", "map_id": "none", "name": "(d)NTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_482627", "map_id": "none", "name": "(d)NDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10692357", "map_id": "none", "name": "NME1,2 hexamers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10689230", "map_id": "none", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10689227", "map_id": "none", "name": "RNR (M1M2B)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8IJN8", "map_id": "Q8IJN8", "name": "RRM2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10688340", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10688337", "map_id": "none", "name": "CTPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10702420", "map_id": "none", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10688350", "map_id": "none", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10688347", "map_id": "none", "name": "DUT trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8II92", "map_id": "Q8II92", "name": "DUT-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1127100", "map_id": "PF3D7_1127100", "name": "DUT-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10692257", "map_id": "none", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5462", "compartment_display": "mitochondrion" }, { "id": "species_10692254", "map_id": "none", "name": "NNT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q8IKU3", "map_id": "Q8IKU3", "name": "NNT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1453500", "map_id": "PF3D7_1453500", "name": "NNT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687520", "map_id": "none", "name": "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113536", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687517", "map_id": "none", "name": "SUCLG1:SUCLG2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8IIR8", "map_id": "Q8IIR8", "name": "SUCLG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1108500", "map_id": "PF3D7_1108500", "name": "SUCLG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8ILE9", "map_id": "Q8ILE9", "name": "SUCLG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1431600", "map_id": "PF3D7_1431600", "name": "SUCLG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687364", "map_id": "none", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29654", "map_id": "CHEBI:30769", "name": "CIT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10687361", "map_id": "none", "name": "CS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I6U7", "map_id": "Q8I6U7", "name": "CS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1022500", "map_id": "PF3D7_1022500", "name": "CS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10687428", "map_id": "none", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10692267", "map_id": "none", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29938", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10692264", "map_id": "none", "name": "IDH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q8I6T2", "map_id": "Q8I6T2", "name": "IDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1345700", "map_id": "PF3D7_1345700", "name": "IDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10691918", "map_id": "none", "name": "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_114523", "map_id": "CHEBI:28790", "name": "5HT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10691915", "map_id": "O96181", "name": "SLC6A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10687636", "map_id": "none", "name": "Internal Methylation of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10687616", "map_id": "none", "name": "capped, methylated pre-mRNA:CBC Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10687633", "map_id": "none", "name": "mRNA (N6-adenosine)-methyltransferase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8I6Z2", "map_id": "Q8I6Z2", "name": "METTL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0729500", "map_id": "PF3D7_0729500", "name": "METTL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I567", "map_id": "Q8I567", "name": "METTL14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1235500", "map_id": "PF3D7_1235500", "name": "METTL14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5B2", "map_id": "Q8I5B2", "name": "WTAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1230800", "map_id": "PF3D7_1230800", "name": "WTAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10694523", "map_id": "none", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2161525", "map_id": "none", "name": "abacavir", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_2161185", "map_id": "none", "name": "abacavir", "type": "product", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10694520", "map_id": "none", "name": "SLC22A1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10690615", "map_id": "none", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10690542", "map_id": "C0H553", "name": "MyrG-NOS3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690595", "map_id": "C0H553", "name": "2xPalmC-MyrG-NOS3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10690612", "map_id": "none", "name": "Homologues of ZDHHC21", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q8IIK6", "map_id": "Q8IIK6", "name": "ZDHHC21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1322500", "map_id": "PF3D7_1322500", "name": "ZDHHC21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A143ZYC1", "map_id": "A0A143ZYC1", "name": "ZDHHC21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE90", "map_id": "Q8IE90", "name": "ZDHHC21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10690550", "map_id": "none", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10690544", "map_id": "none", "name": "myristoylated eNOS dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10690548", "map_id": "none", "name": "myristoylated eNOS dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10690629", "map_id": "none", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10690619", "map_id": "none", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_184174", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10690617", "map_id": "C0H553", "name": "NOS3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10693934", "map_id": "none", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1222424", "map_id": "CHEBI:18421", "name": "O2.-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10691747", "map_id": "none", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10691712", "map_id": "none", "name": "Lsm1-7 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "C0H4W2", "map_id": "C0H4W2", "name": "LSM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0819900", "map_id": "PF3D7_0819900", "name": "LSM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IE68", "map_id": "Q8IE68", "name": "LSM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1325000", "map_id": "PF3D7_1325000", "name": "LSM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I3Q7", "map_id": "Q8I3Q7", "name": "LSM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_0520300", "map_id": "PF3D7_0520300", "name": "LSM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIT3", "map_id": "Q8IIT3", "name": "LSM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1107000", "map_id": "PF3D7_1107000", "name": "LSM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IIB9", "map_id": "Q8IIB9", "name": "LSM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1124400", "map_id": "PF3D7_1124400", "name": "LSM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8IL38", "map_id": "Q8IL38", "name": "LSM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1443300", "map_id": "PF3D7_1443300", "name": "LSM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8I5V6", "map_id": "Q8I5V6", "name": "LSM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PF3D7_1209200", "map_id": "PF3D7_1209200", "name": "LSM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429974", "map_id": "none", "name": "mature mRNA (eukaryotic, capped and deadenylated)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10691714", "map_id": "none", "name": "Deadenylated mRNA:Lsm1-7 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10691745", "map_id": "none", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10703241", "map_id": "none", "name": "SFTPD trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10703243", "map_id": "none", "name": "SFTPD 12mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10703484", "map_id": "none", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. 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High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686949" ], "products": [ "species_10686964" ], "modifiers": [], "additional_components": [ "PF3D7_0503200", "PF3D7_0503200" ] }, "reaction_10686972": { "compartment": "compartment_70101", "id": "reaction_10686972", "reactome": "R-PFA-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686970" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I469", "PF3D7_0503200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10691078": { "compartment": "compartment_70101", "id": "reaction_10691078", "reactome": "R-PFA-379464", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9677997", "species_71284" ], "products": [ "species_9677992", "species_174369" ], "modifiers": [ [ "species_10691067", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10703494": { "compartment": "compartment_1598585", "id": "reaction_10703494", "reactome": "R-PFA-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10699285" ], "products": [ "species_10703486", "species_29420" ], "modifiers": [ [ "species_10703491", "catalyst" ] ], "additional_components": [ "Q7KQK6", "PF3D7_1117700", "species_29420", "Q7KQK6", "PF3D7_1117700", "species_29438", "PF3D7_0711500" ] }, "reaction_10703498": { "compartment": "compartment_70101", "id": "reaction_10703498", "reactome": "R-PFA-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10703486" ], "products": [ "species_10703496" ], "modifiers": [], "additional_components": [ "Q7KQK6", "PF3D7_1117700", "species_29438", "Q7KQK6", "PF3D7_1117700", "species_29438" ] }, "reaction_10691051": { "compartment": "compartment_876", "id": "reaction_10691051", "reactome": "R-PFA-374896", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10691300": { "compartment": "compartment_70101", "id": "reaction_10691300", "reactome": "R-PFA-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10691297", "catalyst" ] ], "additional_components": [ "Q8IKD3", "PF3D7_1470500", "Q8I6Z7", "PF3D7_1321500.1", "B3FEM7", "PF3D7_1321600" ] }, "reaction_10691242": { "compartment": "compartment_70101", "id": "reaction_10691242", "reactome": "R-PFA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10691239", "catalyst" ] ], "additional_components": [ "C0H553", "PF3D7_0923200" ] }, "reaction_10699877": { "compartment": "compartment_1222693", "id": "reaction_10699877", "reactome": "R-PFA-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_1629751", "species_29370" ], "modifiers": [ [ "species_10699874", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10703237": { "compartment": "compartment_70101", "id": "reaction_10703237", "reactome": "R-PFA-8959510", "name": "SEPHS2 phosphorylates H2Se to form SELP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357660", "species_29356", "species_113592" ], "products": [ "species_29372", "species_70106", "species_8959518", "species_76577" ], "modifiers": [ [ "species_10703234", "catalyst" ] ], "additional_components": [ "PF3D7_0910400" ] }, "reaction_10694885": { "compartment": "compartment_70101", "id": "reaction_10694885", "reactome": "R-PFA-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694412", "species_10690526", "species_74016" ], "products": [ "species_10694857" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "Q8IKV9", "PF3D7_1451700", "species_74016", "P62203", "PF14_0323", "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700" ] }, "reaction_10695764": { "compartment": "compartment_70101", "id": "reaction_10695764", "reactome": "R-PFA-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695758" ], "products": [ "species_10695762" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700", "species_74016", "Q8IKV9", "PF3D7_1451700", "P62203", "PF14_0323", "Q8IAM8", "PF3D7_0802800", "CHEBI:29034", "species_216785" ] }, "reaction_10695726": { "compartment": "compartment_7660", "id": "reaction_10695726", "reactome": "R-PFA-4411373", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695720" ], "products": [ "species_10695724" ], "modifiers": [], "additional_components": [ "Q7KQK7", "PF3D7_1113900", "Q7KQK7", "PF3D7_1113900" ] }, "reaction_10693951": { "compartment": "compartment_70101", "id": "reaction_10693951", "reactome": "R-PFA-1504193", "name": "Ubiquitinated DVL is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693946" ], "products": [ "species_10686740", "species_10693938" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10693949": { "compartment": "compartment_70101", "id": "reaction_10693949", "reactome": "R-PFA-1504190", "name": "DVL is ubiquitinated by CUL3:KLHL12:RBX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10693942" ], "products": [ "species_10693946" ], "modifiers": [ [ "species_10693942", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10690643": { "compartment": "compartment_7660", "id": "reaction_10690643", "reactome": "R-PFA-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10690340" ], "products": [ "species_113550", "species_10690391" ], "modifiers": [ [ "species_10690640", "catalyst" ] ], "additional_components": [ "Q7KQK7", "PF3D7_1113900", "Q7KQK7", "PF3D7_1113900", "Q8IKS8", "PF3D7_1455100" ] }, "reaction_10690343": { "compartment": "compartment_7660", "id": "reaction_10690343", "reactome": "R-PFA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10690313" ], "products": [ "species_113582", "species_10690338" ], "modifiers": [ [ "species_10690340", "catalyst" ] ], "additional_components": [ "Q8I4W3", "PF3D7_1246900", "Q8I4W3", "PF3D7_1246900", "Q7KQK7", "PF3D7_1113900" ] }, "reaction_10697570": { "compartment": "compartment_7660", "id": "reaction_10697570", "reactome": "R-PFA-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697549" ], "products": [ "species_10697568" ], "modifiers": [], "additional_components": [ "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900" ] }, "reaction_10698160": { "compartment": "compartment_70101", "id": "reaction_10698160", "reactome": "R-PFA-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698156", "species_10695314" ], "products": [ "species_10698158" ], "modifiers": [], "additional_components": [ "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "PF3D7_0201800", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900" ] }, "reaction_10698170": { "compartment": "compartment_70101", "id": "reaction_10698170", "reactome": "R-PFA-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698158", "species_113592" ], "products": [ "species_29370", "species_10698167" ], "modifiers": [ [ "species_10698158", "catalyst" ] ], "additional_components": [ "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900" ] }, "reaction_10697560": { "compartment": "compartment_7660", "id": "reaction_10697560", "reactome": "R-PFA-5687088", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10697538" ], "products": [ "species_113582", "species_10697549" ], "modifiers": [ [ "species_10697557", "catalyst" ] ], "additional_components": [ "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800", "C0H4P1", "PF3D7_0934800" ] }, "reaction_10688929": { "compartment": "compartment_7660", "id": "reaction_10688929", "reactome": "R-PFA-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688922" ], "products": [ "species_10688926", "species_29554" ], "modifiers": [ [ "species_10688922", "catalyst" ] ], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000" ] }, "reaction_10688945": { "compartment": "compartment_7660", "id": "reaction_10688945", "reactome": "R-PFA-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688940" ], "products": [ "species_110223", "species_10688942" ], "modifiers": [ [ "species_10688940", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688966": { "compartment": "compartment_7660", "id": "reaction_10688966", "reactome": "R-PFA-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688963" ], "products": [ "species_5637659", "species_10688942" ], "modifiers": [ [ "species_10688963", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688936": { "compartment": "compartment_7660", "id": "reaction_10688936", "reactome": "R-PFA-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688933" ], "products": [ "species_10688926", "species_110216" ], "modifiers": [ [ "species_10688933", "catalyst" ] ], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000" ] }, "reaction_10688952": { "compartment": "compartment_7660", "id": "reaction_10688952", "reactome": "R-PFA-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688949" ], "products": [ "species_10688942", "species_110225" ], "modifiers": [ [ "species_10688949", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688959": { "compartment": "compartment_7660", "id": "reaction_10688959", "reactome": "R-PFA-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688956" ], "products": [ "species_10688942", "species_30140" ], "modifiers": [ [ "species_10688956", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688990": { "compartment": "compartment_7660", "id": "reaction_10688990", "reactome": "R-PFA-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688987" ], "products": [ "species_10688982", "species_5636006" ], "modifiers": [ [ "species_10688987", "catalyst" ] ], "additional_components": [ "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100" ] }, "reaction_10703130": { "compartment": "compartment_17906", "id": "reaction_10703130", "reactome": "R-PFA-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703122" ], "products": [ "species_10703128" ], "modifiers": [], "additional_components": [ "Q8IHR5", "PF3D7_1145200", "C0H563", "PF3D7_1145200", "Q8IHR5", "PF3D7_1145200", "C0H563", "PF3D7_1145200" ] }, "reaction_10699391": { "compartment": "compartment_984", "id": "reaction_10699391", "reactome": "R-PFA-6789310", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174675", "species_6789319" ], "modifiers": [ [ "species_10699388", "catalyst" ] ], "additional_components": [ "Q8II98", "PF3D7_1126600" ] }, "reaction_10691303": { "compartment": "compartment_70101", "id": "reaction_10691303", "reactome": "R-PFA-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10691295", "catalyst" ] ], "additional_components": [ "Q8IKD3", "PF3D7_1470500", "Q8I6Z7", "PF3D7_1321500.1", "B3FEM7", "PF3D7_1321600" ] }, "reaction_10695969": { "compartment": "compartment_7660", "id": "reaction_10695969", "reactome": "R-PFA-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10687012" ], "products": [ "species_10695967", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF13_0328", "Q8I444", "PF3D7_0505800", "P61074", "PF13_0328", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10696010": { "compartment": "compartment_7660", "id": "reaction_10696010", "reactome": "R-PFA-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10696001" ], "products": [ "species_10696008", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1433500", "Q8ILC8", "PF3D7_1433500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695999": { "compartment": "compartment_7660", "id": "reaction_10695999", "reactome": "R-PFA-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695989" ], "products": [ "species_10695997", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1433500", "Q8I444", "PF3D7_0505800", "Q8ILC8", "PF3D7_1433500", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10696015": { "compartment": "compartment_7660", "id": "reaction_10696015", "reactome": "R-PFA-4641350", "name": "PIAS4 SUMOylates TOP2A with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695835", "species_10695989" ], "products": [ "species_10696013", "species_10694930" ], "modifiers": [ [ "species_10695666", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1433500", "PF3D7_1433500", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10696030": { "compartment": "compartment_7660", "id": "reaction_10696030", "reactome": "R-PFA-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10696020" ], "products": [ "species_10696028", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0510500", "Q8I3Z9", "PF3D7_0510500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10690228": { "compartment": "compartment_70101", "id": "reaction_10690228", "reactome": "R-PFA-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_113592", "species_196786" ], "products": [ "species_111294", "species_196834", "species_76577" ], "modifiers": [ [ "species_10690225", "catalyst" ] ], "additional_components": [ "Q9U0G7", "PF3D7_0412300" ] }, "reaction_10690248": { "compartment": "compartment_70101", "id": "reaction_10690248", "reactome": "R-PFA-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10690245", "catalyst" ] ], "additional_components": [ "Q8IAZ8", "PF3D7_0816100", "species_73524" ] }, "reaction_10694915": { "compartment": "compartment_7660", "id": "reaction_10694915", "reactome": "R-PFA-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10694902", "species_10694897" ], "products": [ "species_164121", "species_113541", "species_10694912" ], "modifiers": [ [ "species_10694897", "catalyst" ] ], "additional_components": [ "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8I444", "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000" ] }, "reaction_10694941": { "compartment": "compartment_7660", "id": "reaction_10694941", "reactome": "R-PFA-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694912", "species_10694930" ], "products": [ "species_10694938", "species_10694897" ], "modifiers": [ [ "species_10694897", "catalyst" ] ], "additional_components": [ "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000" ] }, "reaction_10689122": { "compartment": "compartment_7660", "id": "reaction_10689122", "reactome": "R-PFA-110354", "name": "Displacement of OGG1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689114", "species_10688982" ], "products": [ "species_10689116", "species_10688971" ], "modifiers": [], "additional_components": [ "PF3D7_0305600", "Q8I2Y2", "PF3D7_0917100", "O97240", "PF3D7_0305600", "PF3D7_0917100" ] }, "reaction_10689120": { "compartment": "compartment_7660", "id": "reaction_10689120", "reactome": "R-PFA-110352", "name": "Displacement of NTHL1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688942", "species_10689114" ], "products": [ "species_10689116", "species_10688913" ], "modifiers": [], "additional_components": [ "C6KSY9", "PF3D7_0614800", "PF3D7_0305600", "O97240", "PF3D7_0305600", "PF3D7_0614800" ] }, "reaction_10689126": { "compartment": "compartment_7660", "id": "reaction_10689126", "reactome": "R-PFA-110356", "name": "Displacement of MPG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689114", "species_10689014" ], "products": [ "species_10689116", "species_10688976" ], "modifiers": [], "additional_components": [ "PF3D7_0305600", "Q8IKG6", "PF3D7_1467100", "O97240", "PF3D7_0305600", "PF3D7_1467100" ] }, "reaction_10689124": { "compartment": "compartment_7660", "id": "reaction_10689124", "reactome": "R-PFA-110355", "name": "Displacement of MUTYH glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689005", "species_10689114" ], "products": [ "species_10689116", "species_10689001" ], "modifiers": [], "additional_components": [ "A0A143ZYC4", "PF3D7_1129500", "PF3D7_0305600", "O97240", "PF3D7_0305600", "A0A143ZYC4", "PF3D7_1129500" ] }, "reaction_10689118": { "compartment": "compartment_7660", "id": "reaction_10689118", "reactome": "R-PFA-110349", "name": "Displacement of UNG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688926", "species_10689114" ], "products": [ "species_10689116", "species_10688920" ], "modifiers": [], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "PF3D7_0305600", "O97240", "PF3D7_0305600", "PF3D7_1415000" ] }, "reaction_10694851": { "compartment": "compartment_876", "id": "reaction_10694851", "reactome": "R-PFA-2534365", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10694848", "catalyst" ] ], "additional_components": [ "Q8ILA3", "PF3D7_1436100" ] }, "reaction_10695003": { "compartment": "compartment_7660", "id": "reaction_10695003", "reactome": "R-PFA-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694993" ], "products": [ "species_29478", "species_10694995" ], "modifiers": [ [ "species_10695000", "catalyst" ] ], "additional_components": [ "PF3D7_1211600" ] }, "reaction_10697178": { "compartment": "compartment_7660", "id": "reaction_10697178", "reactome": "R-PFA-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696046" ], "products": [ "species_29478", "species_10694993" ], "modifiers": [ [ "species_10695000", "catalyst" ] ], "additional_components": [ "PF3D7_1211600" ] }, "reaction_10696062": { "compartment": "compartment_7660", "id": "reaction_10696062", "reactome": "R-PFA-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696046", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_10694993", "species_159939" ], "modifiers": [ [ "species_10696059", "catalyst" ] ], "additional_components": [ "Q8IAT4", "PF3D7_0809900" ] }, "reaction_10697164": { "compartment": "compartment_7660", "id": "reaction_10697164", "reactome": "R-PFA-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696441", "species_113671", "species_113685" ], "products": [ "species_10696046", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10696059", "catalyst" ] ], "additional_components": [ "Q8IAT4", "PF3D7_0809900" ] }, "reaction_10695575": { "compartment": "compartment_7660", "id": "reaction_10695575", "reactome": "R-PFA-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10695561" ], "products": [ "species_10695567", "species_5566518" ], "modifiers": [ [ "species_10695572", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "PF3D7_1008000" ] }, "reaction_10696930": { "compartment": "compartment_7660", "id": "reaction_10696930", "reactome": "R-PFA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694993" ], "products": [ "species_77502", "species_10696046" ], "modifiers": [ [ "species_10696443", "catalyst" ] ], "additional_components": [ "PF3D7_1355300" ] }, "reaction_10696961": { "compartment": "compartment_7660", "id": "reaction_10696961", "reactome": "R-PFA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696040" ], "products": [ "species_77502", "species_10696949" ], "modifiers": [ [ "species_10696101", "catalyst" ] ], "additional_components": [ "Q8IIL1", "PF3D7_1115200", "Q8I352", "PF3D7_1115200", "Q8IDE8", "PF3D7_1355300" ] }, "reaction_10696688": { "compartment": "compartment_7660", "id": "reaction_10696688", "reactome": "R-PFA-5423038", "name": "SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10689874" ], "products": [ "species_77502", "species_10694646" ], "modifiers": [ [ "species_10694706", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "PF3D7_0403900" ] }, "reaction_10696104": { "compartment": "compartment_7660", "id": "reaction_10696104", "reactome": "R-PFA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694995" ], "products": [ "species_77502", "species_10696040" ], "modifiers": [ [ "species_10696101", "catalyst" ] ], "additional_components": [ "Q8IIL1", "PF3D7_1115200", "Q8I352", "PF3D7_1115200", "Q8IDE8", "PF3D7_1355300" ] }, "reaction_10696446": { "compartment": "compartment_7660", "id": "reaction_10696446", "reactome": "R-PFA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696046" ], "products": [ "species_77502", "species_10696441" ], "modifiers": [ [ "species_10696443", "catalyst" ], [ "species_10696247", "inhibitor" ] ], "additional_components": [ "PF3D7_1355300" ] }, "reaction_10695392": { "compartment": "compartment_7660", "id": "reaction_10695392", "reactome": "R-PFA-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10689874" ], "products": [ "species_2485002", "species_10695365" ], "modifiers": [ [ "species_10695389", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300", "C0H4A7", "PF3D7_0416400" ] }, "reaction_10696439": { "compartment": "compartment_7660", "id": "reaction_10696439", "reactome": "R-PFA-5229203", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696420" ], "products": [ "species_77502", "species_10696437" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696182": { "compartment": "compartment_7660", "id": "reaction_10696182", "reactome": "R-PFA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10689874" ], "products": [ "species_77502", "species_10696172" ], "modifiers": [ [ "species_10696179", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IHP7", "PF3D7_1147300", "Q8ILK1", "PF3D7_1426200" ] }, "reaction_10696293": { "compartment": "compartment_7660", "id": "reaction_10696293", "reactome": "R-PFA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696273" ], "products": [ "species_77502", "species_10696290" ], "modifiers": [ [ "species_10695008", "catalyst" ] ], "additional_components": [ "PF3D7_1426200" ] }, "reaction_10696219": { "compartment": "compartment_7660", "id": "reaction_10696219", "reactome": "R-PFA-5205820", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696199" ], "products": [ "species_77502", "species_10696216" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696249": { "compartment": "compartment_7660", "id": "reaction_10696249", "reactome": "R-PFA-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696235" ], "products": [ "species_77502", "species_10696247" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696335": { "compartment": "compartment_7660", "id": "reaction_10696335", "reactome": "R-PFA-5225649", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695387", "species_10694995" ], "products": [ "species_10696333" ], "modifiers": [ [ "species_10696321", "inhibitor" ] ], "additional_components": [ "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300", "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300" ] }, "reaction_10697183": { "compartment": "compartment_7660", "id": "reaction_10697183", "reactome": "R-PFA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696172", "species_77087" ], "products": [ "species_77502", "species_10697181" ], "modifiers": [ [ "species_10696179", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IHP7", "PF3D7_1147300", "Q8ILK1", "PF3D7_1426200" ] }, "reaction_10697206": { "compartment": "compartment_70101", "id": "reaction_10697206", "reactome": "R-PFA-5665871", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697198", "species_10686934" ], "products": [ "species_10697200" ], "modifiers": [], "additional_components": [ "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000" ] }, "reaction_10698293": { "compartment": "compartment_70101", "id": "reaction_10698293", "reactome": "R-PFA-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698284", "species_29356" ], "products": [ "species_10698288", "species_10698290" ], "modifiers": [ [ "species_10698284", "catalyst" ] ], "additional_components": [ "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "PF3D7_1313000", "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000" ] }, "reaction_10697204": { "compartment": "compartment_70101", "id": "reaction_10697204", "reactome": "R-PFA-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697193", "species_10697200" ], "products": [ "species_10697202" ], "modifiers": [], "additional_components": [ "PF3D7_1117100", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "Q8IIJ6", "PF3D7_1117100" ] }, "reaction_10698267": { "compartment": "compartment_70101", "id": "reaction_10698267", "reactome": "R-PFA-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698262" ], "products": [ "species_1131871", "species_10698264" ], "modifiers": [ [ "species_10698262", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400" ] }, "reaction_10687165": { "compartment": "compartment_70101", "id": "reaction_10687165", "reactome": "R-PFA-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10687122", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10687018": { "compartment": "compartment_7660", "id": "reaction_10687018", "reactome": "R-PFA-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10687005", "species_10687014" ], "products": [ "species_113582", "species_10687016" ], "modifiers": [], "additional_components": [ "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "P61074", "PF13_0328", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10687007": { "compartment": "compartment_7660", "id": "reaction_10687007", "reactome": "R-PFA-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686939", "species_10687003" ], "products": [ "species_10687005" ], "modifiers": [], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10687022": { "compartment": "compartment_7660", "id": "reaction_10687022", "reactome": "R-PFA-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687016" ], "products": [ "species_10687020", "species_10687003" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100" ] }, "reaction_10687059": { "compartment": "compartment_7660", "id": "reaction_10687059", "reactome": "R-PFA-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687055", "species_10687050" ], "products": [ "species_10687057" ], "modifiers": [], "additional_components": [ "PF3D7_1333900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "A0A5K1K9F2", "PF3D7_1333900" ] }, "reaction_10687071": { "compartment": "compartment_7660", "id": "reaction_10687071", "reactome": "R-PFA-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687061" ], "products": [ "species_10687063" ], "modifiers": [ [ "species_10687068", "catalyst" ] ], "additional_components": [ "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "PFD0420c" ] }, "reaction_10687079": { "compartment": "compartment_7660", "id": "reaction_10687079", "reactome": "R-PFA-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10687076", "catalyst" ] ], "additional_components": [ "PF3D7_1304100" ] }, "reaction_10687046": { "compartment": "compartment_7660", "id": "reaction_10687046", "reactome": "R-PFA-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687042" ], "products": [ "species_10687044" ], "modifiers": [], "additional_components": [ "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10689433": { "compartment": "compartment_70101", "id": "reaction_10689433", "reactome": "R-PFA-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689420", "species_10689429" ], "products": [ "species_10689431" ], "modifiers": [], "additional_components": [ "PF3D7_1004000", "Q8I5H4", "PF3D7_1224300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8I5H4", "PF3D7_1224300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJZ7", "PF3D7_1004000" ] }, "reaction_10689437": { "compartment": "compartment_70101", "id": "reaction_10689437", "reactome": "R-PFA-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688213" ], "products": [ "species_10688008", "species_10689435" ], "modifiers": [], "additional_components": [ "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "PF3D7_1004000", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200" ] }, "reaction_10698371": { "compartment": "compartment_70101", "id": "reaction_10698371", "reactome": "R-PFA-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29418", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1981162" ], "modifiers": [ [ "species_10698368", "catalyst" ] ], "additional_components": [ "PF3D7_0727800" ] }, "reaction_10691233": { "compartment": "compartment_114521", "id": "reaction_10691233", "reactome": "R-PFA-418365", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427899", "species_74016" ], "products": [ "species_70106", "species_139827" ], "modifiers": [ [ "species_10691230", "catalyst" ] ], "additional_components": [ "Q76NN8", "PF3D7_1211900", "A0A143ZZK9", "PF3D7_1211900" ] }, "reaction_10693014": { "compartment": "compartment_70101", "id": "reaction_10693014", "reactome": "R-PFA-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_947588", "species_113592" ], "products": [ "species_29372", "species_29370", "species_947594" ], "modifiers": [ [ "species_10692986", "catalyst" ] ], "additional_components": [ "species_1500646", "species_1500581", "species_1500581", "species_1500646", "Q8IKF1", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600" ] }, "reaction_10691562": { "compartment": "compartment_12045", "id": "reaction_10691562", "reactome": "R-PFA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_74016" ], "products": [ "species_70106", "species_111875" ], "modifiers": [ [ "species_10691559", "catalyst" ] ], "additional_components": [ "Q76NN8", "PF3D7_1211900", "A0A143ZZK9", "PF3D7_1211900" ] }, "reaction_10691208": { "compartment": "compartment_876", "id": "reaction_10691208", "reactome": "R-PFA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10691205", "catalyst" ] ], "additional_components": [ "A0A5K1K8L6", "PF3D7_1348800" ] }, "reaction_10698376": { "compartment": "compartment_70101", "id": "reaction_10698376", "reactome": "R-PFA-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5692450" ], "products": [ "species_29372", "species_29370", "species_5692484" ], "modifiers": [ [ "species_10698373", "catalyst" ] ], "additional_components": [ "PF3D7_0516100" ] }, "reaction_10696494": { "compartment": "compartment_70101", "id": "reaction_10696494", "reactome": "R-PFA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5252122", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5252016" ], "modifiers": [ [ "species_10696491", "catalyst" ] ], "additional_components": [ "Q8I3U7", "PF3D7_0516100" ] }, "reaction_10699216": { "compartment": "compartment_7660", "id": "reaction_10699216", "reactome": "R-PFA-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699209", "species_6781829" ], "products": [ "species_10699213", "species_113541" ], "modifiers": [ [ "species_10699209", "catalyst" ] ], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10699211": { "compartment": "compartment_7660", "id": "reaction_10699211", "reactome": "R-PFA-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687612", "species_10688666", "species_5688114" ], "products": [ "species_10699209" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10691010": { "compartment": "compartment_70101", "id": "reaction_10691010", "reactome": "R-PFA-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691000" ], "products": [ "species_10691008" ], "modifiers": [], "additional_components": [ "Q8IHR4", "PF3D7_1218500", "Q8IJ32", "PF3D7_1218500", "Q8I5M3", "PF3D7_1218500", "Q8I5M3", "PF3D7_1218500", "Q8IJ32", "PF3D7_1218500", "Q8IHR4", "PF3D7_1218500" ] }, "reaction_10690941": { "compartment": "compartment_7660", "id": "reaction_10690941", "reactome": "R-PFA-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690937", "species_29428" ], "products": [ "species_10690939" ], "modifiers": [], "additional_components": [ "Q8I616", "PF3D7_1202900", "Q8I616", "PF3D7_1202900" ] }, "reaction_10703624": { "compartment": "compartment_70101", "id": "reaction_10703624", "reactome": "R-PFA-9661417", "name": "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5679042" ], "products": [ "species_29372", "species_5679034", "species_29370" ], "modifiers": [ [ "species_10692753", "catalyst" ] ], "additional_components": [ "CHEBI:18392", "CHEBI:16427", "CHEBI:16427", "CHEBI:18392", "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690066": { "compartment": "compartment_5460", "id": "reaction_10690066", "reactome": "R-PFA-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_70958", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10690063", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "Q8I4X1", "PF3D7_1246100" ] }, "reaction_10690082": { "compartment": "compartment_70101", "id": "reaction_10690082", "reactome": "R-PFA-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10690035", "catalyst" ] ], "additional_components": [ "C6KSS1", "PF3D7_0607300" ] }, "reaction_10690018": { "compartment": "compartment_17927", "id": "reaction_10690018", "reactome": "R-PFA-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189411" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10690015", "catalyst" ] ], "additional_components": [ "Q8IHU1", "PF3D7_1142400" ] }, "reaction_10690080": { "compartment": "compartment_70101", "id": "reaction_10690080", "reactome": "R-PFA-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190173", "species_10690045" ], "products": [ "species_10690078", "species_29426" ], "modifiers": [], "additional_components": [ "species_216785", "Q8IL68", "PF3D7_1440300", "species_216785", "Q8IL68", "PF3D7_1440300", "species_391232" ] }, "reaction_10690048": { "compartment": "compartment_70101", "id": "reaction_10690048", "reactome": "R-PFA-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_29356", "species_70106", "species_189464" ], "modifiers": [ [ "species_10690045", "catalyst" ] ], "additional_components": [ "species_216785", "Q8IL68", "PF3D7_1440300" ] }, "reaction_10690038": { "compartment": "compartment_70101", "id": "reaction_10690038", "reactome": "R-PFA-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_189455", "species_113528" ], "modifiers": [ [ "species_10690035", "catalyst" ] ], "additional_components": [ "C6KSS1", "PF3D7_0607300" ] }, "reaction_10694949": { "compartment": "compartment_5460", "id": "reaction_10694949", "reactome": "R-PFA-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189444", "species_2162257", "species_113521" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10694946", "catalyst" ] ], "additional_components": [ "PF3D7_0519300" ] }, "reaction_10692756": { "compartment": "compartment_876", "id": "reaction_10692756", "reactome": "R-PFA-917979", "name": "ABCG2 tetramer transports heme from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_71185" ], "products": [ "species_29372", "species_917877", "species_29370" ], "modifiers": [ [ "species_10692753", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690008": { "compartment": "compartment_70101", "id": "reaction_10690008", "reactome": "R-PFA-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_189464" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10690005", "catalyst" ] ], "additional_components": [ "Q8I5V3", "PF3D7_1209600", "CHEBI:36319" ] }, "reaction_10694957": { "compartment": "compartment_5460", "id": "reaction_10694957", "reactome": "R-PFA-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10694954", "catalyst" ] ], "additional_components": [ "PF3D7_1435000" ] }, "reaction_10690028": { "compartment": "compartment_17927", "id": "reaction_10690028", "reactome": "R-PFA-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10690025", "catalyst" ] ], "additional_components": [ "Q8IJC3", "PF3D7_1028100", "species_29386" ] }, "reaction_10690076": { "compartment": "compartment_5460", "id": "reaction_10690076", "reactome": "R-PFA-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_113529", "species_189444" ], "modifiers": [ [ "species_10690073", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "Q8ID58", "PF3D7_1364900" ] }, "reaction_10689488": { "compartment": "compartment_70101", "id": "reaction_10689488", "reactome": "R-PFA-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689484", "species_29438" ], "products": [ "species_10689486" ], "modifiers": [], "additional_components": [ "PF3D7_1451100", "species_29438", "Q8IKW5", "PF3D7_1451100" ] }, "reaction_10701428": { "compartment": "compartment_20699", "id": "reaction_10701428", "reactome": "R-PFA-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696892", "species_10701424" ], "products": [ "species_10701426" ], "modifiers": [], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10701434": { "compartment": "compartment_20699", "id": "reaction_10701434", "reactome": "R-PFA-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701274", "species_10701430" ], "products": [ "species_10701432" ], "modifiers": [], "additional_components": [ "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700" ] }, "reaction_10701439": { "compartment": "compartment_20699", "id": "reaction_10701439", "reactome": "R-PFA-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701213", "species_10701422" ], "products": [ "species_10701424" ], "modifiers": [], "additional_components": [ "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800" ] }, "reaction_10701437": { "compartment": "compartment_20699", "id": "reaction_10701437", "reactome": "R-PFA-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10701426" ], "products": [ "species_29420", "species_10701430" ], "modifiers": [ [ "species_10701426", "catalyst" ] ], "additional_components": [ "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10701485": { "compartment": "compartment_12045", "id": "reaction_10701485", "reactome": "R-PFA-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10701483", "species_10698587" ], "products": [ "species_10701481" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "C0H5E1", "PF3D7_1326800", "A0A5K1K9E7", "PF3D7_1316800", "O97323", "PF3D7_0320100", "O77313", "PF3D7_0303000", "C0H5E1", "PF3D7_1326800", "A0A5K1K9E7", "PF3D7_1316800", "O77313", "PF3D7_0303000", "O97323", "PF3D7_0320100", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10694883": { "compartment": "compartment_70101", "id": "reaction_10694883", "reactome": "R-PFA-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694861" ], "products": [ "species_10694881" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700", "species_74016", "Q8IKV9", "PF3D7_1451700", "P62203", "PF14_0323", "Q8IAM8", "PF3D7_0802800", "CHEBI:29034", "species_216785" ] }, "reaction_10702926": { "compartment": "compartment_7660", "id": "reaction_10702926", "reactome": "R-PFA-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10702912" ], "products": [ "species_113582", "species_10702923" ], "modifiers": [ [ "species_10692168", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600", "Q8I239", "PF3D7_0110600", "PF3D7_0724600" ] }, "reaction_10701516": { "compartment": "compartment_7660", "id": "reaction_10701516", "reactome": "R-PFA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_29358" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10701513", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10701668": { "compartment": "compartment_70101", "id": "reaction_10701668", "reactome": "R-PFA-8848338", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10701665", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10689972": { "compartment": "compartment_5460", "id": "reaction_10689972", "reactome": "R-PFA-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_31649", "species_188451" ], "modifiers": [ [ "species_10689969", "catalyst" ] ], "additional_components": [ "PF3D7_0306400" ] }, "reaction_10701673": { "compartment": "compartment_70101", "id": "reaction_10701673", "reactome": "R-PFA-8848339", "name": "PNPLA5 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10701670", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10701676": { "compartment": "compartment_70101", "id": "reaction_10701676", "reactome": "R-PFA-8848355", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2534407" ], "products": [ "species_8848337", "species_30209" ], "modifiers": [ [ "species_10701665", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10697441": { "compartment": "compartment_70101", "id": "reaction_10697441", "reactome": "R-PFA-5682285", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5682283", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5229279" ], "modifiers": [ [ "species_10697438", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693632": { "compartment": "compartment_876", "id": "reaction_10693632", "reactome": "R-PFA-1369052", "name": "ABCAs mediate lipid influx", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_29356", "species_113592" ], "products": [ "species_29372", "species_176478", "species_29370" ], "modifiers": [ [ "species_10693627", "catalyst" ] ], "additional_components": [] }, "reaction_10690928": { "compartment": "compartment_876", "id": "reaction_10690928", "reactome": "R-PFA-266082", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_216762", "species_113592" ], "products": [ "species_29372", "species_29370", "species_171095" ], "modifiers": [ [ "species_10690925", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690921": { "compartment": "compartment_876", "id": "reaction_10690921", "reactome": "R-PFA-265783", "name": "ABCG5:ABCG8 transports sterols from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_265784", "species_113592" ], "products": [ "species_29372", "species_29370", "species_265781" ], "modifiers": [ [ "species_10690918", "catalyst" ] ], "additional_components": [ "CHEBI:26125", "species_171149", "CHEBI:26125", "species_171149", "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10701647": { "compartment": "compartment_70101", "id": "reaction_10701647", "reactome": "R-PFA-8848053", "name": "ABCA5 transports CHOL from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_8848047" ], "products": [ "species_29372", "species_176478", "species_29370" ], "modifiers": [ [ "species_10701644", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693647": { "compartment": "compartment_70101", "id": "reaction_10693647", "reactome": "R-PFA-1454928", "name": "ABCG4 may mediate cholesterol efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176478", "species_29356", "species_113592" ], "products": [ "species_171149", "species_29372", "species_29370" ], "modifiers": [ [ "species_10693644", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10693630": { "compartment": "compartment_876", "id": "reaction_10693630", "reactome": "R-PFA-1369028", "name": "ABCAs mediate lipid efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_176478", "species_113592" ], "products": [ "species_171149", "species_29372", "species_29370" ], "modifiers": [ [ "species_10693627", "catalyst" ] ], "additional_components": [] }, "reaction_10697468": { "compartment": "compartment_2133233", "id": "reaction_10697468", "reactome": "R-PFA-5683714", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5684863" ], "products": [ "species_29372", "species_29370", "species_5684869" ], "modifiers": [ [ "species_10697465", "catalyst" ] ], "additional_components": [ "species_194276", "species_1483256", "species_194276", "species_1483256", "PF3D7_0319700" ] }, "reaction_10696352": { "compartment": "compartment_70101", "id": "reaction_10696352", "reactome": "R-PFA-5227009", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696348", "species_10687881" ], "products": [ "species_10696350" ], "modifiers": [], "additional_components": [ "PF3D7_1121700", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IIE9", "PF3D7_1121700" ] }, "reaction_10693652": { "compartment": "compartment_876", "id": "reaction_10693652", "reactome": "R-PFA-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1131652" ], "products": [ "species_29372", "species_29370", "species_1467459" ], "modifiers": [ [ "species_10693649", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10696331": { "compartment": "compartment_70101", "id": "reaction_10696331", "reactome": "R-PFA-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5223341" ], "products": [ "species_5223344", "species_29372", "species_29370" ], "modifiers": [ [ "species_10696328", "catalyst" ] ], "additional_components": [ "Q8IHR3", "PF3D7_1145500" ] }, "reaction_10693657": { "compartment": "compartment_74000", "id": "reaction_10693657", "reactome": "R-PFA-1467466", "name": "ABCA4 mediates atRAL transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_2466098" ], "products": [ "species_29372", "species_29370", "species_975622" ], "modifiers": [ [ "species_10693654", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693640": { "compartment": "compartment_70101", "id": "reaction_10693640", "reactome": "R-PFA-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1454930" ], "products": [ "species_29372", "species_29370", "species_1454919" ], "modifiers": [ [ "species_10693637", "catalyst" ] ], "additional_components": [ "PF3D7_0112200" ] }, "reaction_10697434": { "compartment": "compartment_70101", "id": "reaction_10697434", "reactome": "R-PFA-5682101", "name": "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10697425" ], "products": [ "species_29370", "species_10697431" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "O97278", "PF3D7_0319700", "O97278", "PF3D7_0319700", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10697436": { "compartment": "compartment_12045", "id": "reaction_10697436", "reactome": "R-PFA-5682103", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697421" ], "products": [ "species_10697425" ], "modifiers": [], "additional_components": [ "O97278", "PF3D7_0319700", "O97278", "PF3D7_0319700" ] }, "reaction_10690889": { "compartment": "compartment_984", "id": "reaction_10690889", "reactome": "R-PFA-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_194276" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10690886", "catalyst" ] ], "additional_components": [ "PF3D7_0629300" ] }, "reaction_10692450": { "compartment": "compartment_876", "id": "reaction_10692450", "reactome": "R-PFA-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10692447", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692436": { "compartment": "compartment_876", "id": "reaction_10692436", "reactome": "R-PFA-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10692433", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800", "C0H4T7", "PF3D7_0810400" ] }, "reaction_10692452": { "compartment": "compartment_876", "id": "reaction_10692452", "reactome": "R-PFA-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10692447", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692443": { "compartment": "compartment_876", "id": "reaction_10692443", "reactome": "R-PFA-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10692433", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800", "C0H4T7", "PF3D7_0810400" ] }, "reaction_10692441": { "compartment": "compartment_876", "id": "reaction_10692441", "reactome": "R-PFA-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10692438", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692445": { "compartment": "compartment_876", "id": "reaction_10692445", "reactome": "R-PFA-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10692438", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691955": { "compartment": "compartment_876", "id": "reaction_10691955", "reactome": "R-PFA-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691952", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691777": { "compartment": "compartment_876", "id": "reaction_10691777", "reactome": "R-PFA-432065", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10691774", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691802": { "compartment": "compartment_70101", "id": "reaction_10691802", "reactome": "R-PFA-432232", "name": "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10691795" ], "products": [ "species_29370", "species_10691799" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400", "C0H4T7", "PF3D7_0810400", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10703161": { "compartment": "compartment_70101", "id": "reaction_10703161", "reactome": "R-PFA-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10689282" ], "products": [ "species_10689284" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "species_30389" ] }, "reaction_10691769": { "compartment": "compartment_876", "id": "reaction_10691769", "reactome": "R-PFA-432054", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10689288": { "compartment": "compartment_70101", "id": "reaction_10689288", "reactome": "R-PFA-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689284" ], "products": [ "species_10689286", "species_10689280" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "species_30389", "species_30389", "Q7KQK0", "PF3D7_1223100", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10691784": { "compartment": "compartment_876", "id": "reaction_10691784", "reactome": "R-PFA-432067", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691781", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691757": { "compartment": "compartment_876", "id": "reaction_10691757", "reactome": "R-PFA-432010", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691767": { "compartment": "compartment_876", "id": "reaction_10691767", "reactome": "R-PFA-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10691764", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691791": { "compartment": "compartment_876", "id": "reaction_10691791", "reactome": "R-PFA-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10691788", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10696562": { "compartment": "compartment_70101", "id": "reaction_10696562", "reactome": "R-PFA-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10696559", "catalyst" ] ], "additional_components": [ "PF3D7_1304200.2" ] }, "reaction_10696578": { "compartment": "compartment_70101", "id": "reaction_10696578", "reactome": "R-PFA-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696575", "catalyst" ] ], "additional_components": [ "PF3D7_0107700" ] }, "reaction_10696554": { "compartment": "compartment_70101", "id": "reaction_10696554", "reactome": "R-PFA-5336453", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696551", "catalyst" ] ], "additional_components": [ "A0A144A2U1", "PF3D7_1467000", "Q8IBA9", "PF3D7_1467000" ] }, "reaction_10696573": { "compartment": "compartment_70101", "id": "reaction_10696573", "reactome": "R-PFA-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696570", "catalyst" ] ], "additional_components": [ "PF3D7_0107700" ] }, "reaction_10693563": { "compartment": "compartment_70101", "id": "reaction_10693563", "reactome": "R-PFA-1247649", "name": "AQP1 tetramer transports CO2 from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113528" ], "products": [ "species_1237009" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691843": { "compartment": "compartment_876", "id": "reaction_10691843", "reactome": "R-PFA-435349", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_435347" ], "products": [ "species_70106", "species_71067" ], "modifiers": [ [ "species_10691840", "catalyst" ] ], "additional_components": [ "PF3D7_0523800" ] }, "reaction_10691859": { "compartment": "compartment_876", "id": "reaction_10691859", "reactome": "R-PFA-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10691856", "catalyst" ] ], "additional_components": [ "PF3D7_1439000" ] }, "reaction_10691873": { "compartment": "compartment_876", "id": "reaction_10691873", "reactome": "R-PFA-442422", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10691870", "catalyst" ] ], "additional_components": [ "C6KST8", "PF3D7_0609100" ] }, "reaction_10691851": { "compartment": "compartment_20699", "id": "reaction_10691851", "reactome": "R-PFA-437136", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10691848", "catalyst" ] ], "additional_components": [ "PF3D7_0715900" ] }, "reaction_10691838": { "compartment": "compartment_172574", "id": "reaction_10691838", "reactome": "R-PFA-435171", "name": "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_445829" ], "products": [ "species_445832", "species_1470067" ], "modifiers": [ [ "species_10691835", "catalyst" ] ], "additional_components": [ "species_216785", "species_71067", "species_1981162", "species_216785", "species_1981162", "species_71067", "PF3D7_0523800" ] }, "reaction_10691830": { "compartment": "compartment_876", "id": "reaction_10691830", "reactome": "R-PFA-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_446589" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10691827", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:641", "CHEBI:6801", "CHEBI:16737", "CHEBI:8428", "CHEBI:42820", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "CHEBI:6801", "O96209", "PF3D7_0212800" ] }, "reaction_10692562": { "compartment": "compartment_876", "id": "reaction_10692562", "reactome": "R-PFA-561072", "name": "OCT3 mediates renal uptake of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549255" ], "products": [ "species_549326" ], "modifiers": [ [ "species_10692535", "catalyst" ] ], "additional_components": [ "CHEBI:47781", "CHEBI:8428", "CHEBI:42820", "CHEBI:47499", "CHEBI:641", "CHEBI:46020", "CHEBI:46631", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:47499", "CHEBI:47781", "CHEBI:641", "CHEBI:46631", "PF3D7_1203400" ] }, "reaction_10692533": { "compartment": "compartment_876", "id": "reaction_10692533", "reactome": "R-PFA-549297", "name": "SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164988", "species_74113" ], "products": [ "species_30235", "species_83910" ], "modifiers": [ [ "species_10692530", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10692516": { "compartment": "compartment_876", "id": "reaction_10692516", "reactome": "R-PFA-549129", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549264" ], "products": [ "species_549250" ], "modifiers": [ [ "species_10692513", "catalyst" ] ], "additional_components": [ "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "CHEBI:18295", "species_353560", "species_6798162", "CHEBI:16797", "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "CHEBI:16797", "species_6798162", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "CHEBI:18295", "species_353560", "species_209789", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692538": { "compartment": "compartment_876", "id": "reaction_10692538", "reactome": "R-PFA-549304", "name": "OCT3 mediates renal clearance of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549326" ], "products": [ "species_549255" ], "modifiers": [ [ "species_10692535", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:47499", "CHEBI:47781", "CHEBI:641", "CHEBI:46631", "CHEBI:47781", "CHEBI:8428", "CHEBI:42820", "CHEBI:47499", "CHEBI:641", "CHEBI:46020", "CHEBI:46631", "PF3D7_1203400" ] }, "reaction_10692553": { "compartment": "compartment_876", "id": "reaction_10692553", "reactome": "R-PFA-561054", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549266" ], "products": [ "species_549237" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "CHEBI:16797", "CHEBI:16737", "species_6798162", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "CHEBI:18295", "CHEBI:31941", "species_209789", "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "CHEBI:18295", "species_6798162", "CHEBI:16797", "species_209914", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692521": { "compartment": "compartment_876", "id": "reaction_10692521", "reactome": "R-PFA-549241", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549261", "species_74113" ], "products": [ "species_83910", "species_549260" ], "modifiers": [ [ "species_10692518", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10692575": { "compartment": "compartment_876", "id": "reaction_10692575", "reactome": "R-PFA-597628", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_597604", "species_70106" ], "products": [ "species_351626", "species_597623" ], "modifiers": [ [ "species_10692572", "catalyst" ] ], "additional_components": [ "PF3D7_0516500" ] }, "reaction_10692540": { "compartment": "compartment_876", "id": "reaction_10692540", "reactome": "R-PFA-549322", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549250" ], "products": [ "species_549264" ], "modifiers": [ [ "species_10692513", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "CHEBI:16797", "species_6798162", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "CHEBI:18295", "species_353560", "species_209789", "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "CHEBI:18295", "species_353560", "species_6798162", "CHEBI:16797", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692524": { "compartment": "compartment_876", "id": "reaction_10692524", "reactome": "R-PFA-549279", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549237" ], "products": [ "species_549266" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "CHEBI:18295", "species_6798162", "CHEBI:16797", "species_209914", "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "CHEBI:16797", "CHEBI:16737", "species_6798162", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "CHEBI:18295", "CHEBI:31941", "species_209789", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692560": { "compartment": "compartment_876", "id": "reaction_10692560", "reactome": "R-PFA-561059", "name": "OAT2 and OAT4 mediate transport of sulphate conjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561071" ], "products": [ "species_561062", "species_561075" ], "modifiers": [ [ "species_10692557", "catalyst" ] ], "additional_components": [ "CHEBI:16814", "CHEBI:17474", "CHEBI:17474", "CHEBI:16814", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692551": { "compartment": "compartment_876", "id": "reaction_10692551", "reactome": "R-PFA-561041", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561049" ], "products": [ "species_561078", "species_561075" ], "modifiers": [ [ "species_10692548", "catalyst" ] ], "additional_components": [ "CHEBI:104011", "CHEBI:2453", "CHEBI:2453", "CHEBI:104011", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692567": { "compartment": "compartment_876", "id": "reaction_10692567", "reactome": "R-PFA-561253", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_429056" ], "products": [ "species_373863", "species_30034" ], "modifiers": [ [ "species_10692564", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10691904": { "compartment": "compartment_876", "id": "reaction_10691904", "reactome": "R-PFA-443997", "name": "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935", "species_74113" ], "products": [ "species_209789", "species_83910" ], "modifiers": [ [ "species_10691901", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691015": { "compartment": "compartment_876", "id": "reaction_10691015", "reactome": "R-PFA-351963", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266029" ], "products": [ "species_29424" ], "modifiers": [ [ "species_10691012", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691076": { "compartment": "compartment_984", "id": "reaction_10691076", "reactome": "R-PFA-379393", "name": "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_74113" ], "products": [ "species_83910", "species_159362" ], "modifiers": [ [ "species_10691017", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691913": { "compartment": "compartment_70101", "id": "reaction_10691913", "reactome": "R-PFA-444007", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352003", "species_74113" ], "products": [ "species_352011", "species_83910", "species_352022" ], "modifiers": [ [ "species_10691910", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10691023": { "compartment": "compartment_876", "id": "reaction_10691023", "reactome": "R-PFA-352029", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352007", "species_74113" ], "products": [ "species_351982", "species_83910", "species_352022" ], "modifiers": [ [ "species_10690400", "catalyst" ] ], "additional_components": [ "CHEBI:16958", "species_352011", "CHEBI:17750", "CHEBI:48950", "CHEBI:48950", "CHEBI:16958", "CHEBI:17750", "species_352011", "PF3D7_0209600" ] }, "reaction_10691020": { "compartment": "compartment_876", "id": "reaction_10691020", "reactome": "R-PFA-351987", "name": "SLC6A6-mediated uptake of taurine and beta-alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352024", "species_74113" ], "products": [ "species_83910", "species_352019", "species_352022" ], "modifiers": [ [ "species_10691017", "catalyst" ] ], "additional_components": [ "CHEBI:16958", "CHEBI:15891", "CHEBI:16958", "CHEBI:15891", "PF3D7_0209600" ] }, "reaction_10691058": { "compartment": "compartment_876", "id": "reaction_10691058", "reactome": "R-PFA-375473", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375458", "species_74113" ], "products": [ "species_375481", "species_83910" ], "modifiers": [ [ "species_10691055", "catalyst" ] ], "additional_components": [ "species_29432", "CHEBI:57912", "species_29472", "CHEBI:58045", "species_111707", "species_200736", "species_29424", "CHEBI:57427", "species_379705", "CHEBI:58315", "species_29502", "CHEBI:57762", "species_29424", "species_29472", "CHEBI:58315", "species_200736", "CHEBI:57427", "species_379705", "CHEBI:58045", "CHEBI:57762", "species_29432", "species_111707", "CHEBI:57912", "species_29502", "PF3D7_0209600" ] }, "reaction_10691921": { "compartment": "compartment_876", "id": "reaction_10691921", "reactome": "R-PFA-444100", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538", "species_352022" ], "modifiers": [ [ "species_10690402", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691063": { "compartment": "compartment_876", "id": "reaction_10691063", "reactome": "R-PFA-375487", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_375468", "species_74113" ], "products": [ "species_83910", "species_375459", "species_352022" ], "modifiers": [ [ "species_10691060", "catalyst" ] ], "additional_components": [ "species_29432", "CHEBI:57912", "CHEBI:58045", "CHEBI:32513", "species_200736", "species_29424", "species_29468", "CHEBI:16958", "species_1131871", "species_111707", "CHEBI:57427", "species_379705", "CHEBI:57762", "species_200736", "CHEBI:57762", "CHEBI:32513", "species_1131871", "species_29424", "CHEBI:57427", "species_379705", "CHEBI:58045", "CHEBI:16958", "species_29432", "species_111707", "species_29468", "CHEBI:57912", "PF3D7_0209600" ] }, "reaction_10691028": { "compartment": "compartment_876", "id": "reaction_10691028", "reactome": "R-PFA-352052", "name": "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538" ], "modifiers": [ [ "species_10691025", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691930": { "compartment": "compartment_876", "id": "reaction_10691930", "reactome": "R-PFA-444120", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_266029", "species_74113" ], "products": [ "species_83910", "species_352022", "species_29424" ], "modifiers": [ [ "species_10691927", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10691033": { "compartment": "compartment_876", "id": "reaction_10691033", "reactome": "R-PFA-352059", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352051", "species_74113" ], "products": [ "species_83910", "species_352048" ], "modifiers": [ [ "species_10691030", "catalyst" ] ], "additional_components": [ "species_29432", "species_29472", "CHEBI:58045", "species_379717", "CHEBI:57926", "species_111707", "species_200736", "species_29642", "CHEBI:57427", "species_379705", "CHEBI:18240", "CHEBI:57762", "species_29472", "species_379717", "CHEBI:57926", "species_200736", "CHEBI:57427", "species_379705", "CHEBI:18240", "CHEBI:58045", "CHEBI:57762", "species_29432", "species_29642", "species_111707", "PF3D7_0209600" ] }, "reaction_10691948": { "compartment": "compartment_984", "id": "reaction_10691948", "reactome": "R-PFA-444433", "name": "Cho transports from the extracellular space to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264638" ], "products": [ "species_264618" ], "modifiers": [ [ "species_10691945", "catalyst" ] ], "additional_components": [ "Q8ILE6", "PF3D7_1431900" ] }, "reaction_10702179": { "compartment": "compartment_70101", "id": "reaction_10702179", "reactome": "R-PFA-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_2162265", "species_71285" ], "modifiers": [ [ "species_10702176", "catalyst" ] ], "additional_components": [ "PF3D7_1241600" ] }, "reaction_10691543": { "compartment": "compartment_876", "id": "reaction_10691543", "reactome": "R-PFA-427605", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10691540", "catalyst" ] ], "additional_components": [ "Q8IDS7", "PF3D7_1340900" ] }, "reaction_10692626": { "compartment": "compartment_20699", "id": "reaction_10692626", "reactome": "R-PFA-742345", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742368" ], "products": [ "species_205683" ], "modifiers": [ [ "species_10692623", "catalyst" ] ], "additional_components": [ "PF3D7_0212000" ] }, "reaction_10692613": { "compartment": "compartment_20699", "id": "reaction_10692613", "reactome": "R-PFA-727807", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727810", "species_4085435" ], "products": [ "species_727815", "species_109395" ], "modifiers": [ [ "species_10692610", "catalyst" ] ], "additional_components": [ "PF3D7_0505300" ] }, "reaction_10692618": { "compartment": "compartment_20699", "id": "reaction_10692618", "reactome": "R-PFA-735702", "name": "SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735698", "species_735692" ], "products": [ "species_109402", "species_735691" ], "modifiers": [ [ "species_10692615", "catalyst" ] ], "additional_components": [ "species_735700", "species_735682", "species_735682", "species_735700", "PF3D7_0505300" ] }, "reaction_10688817": { "compartment": "compartment_70101", "id": "reaction_10688817", "reactome": "R-PFA-109536", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737" ], "products": [ "species_179743" ], "modifiers": [ [ "species_10688812", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:16335", "CHEBI:17562", "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692593": { "compartment": "compartment_70101", "id": "reaction_10692593", "reactome": "R-PFA-727749", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727782" ], "products": [ "species_727746" ], "modifiers": [ [ "species_10692590", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17596", "CHEBI:16704", "CHEBI:16750", "CHEBI:17562", "CHEBI:17748", "species_5635947", "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "species_5635947", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10689584": { "compartment": "compartment_70616", "id": "reaction_10689584", "reactome": "R-PFA-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10689581", "catalyst" ] ], "additional_components": [ "Q8IJ34", "PF3D7_1037300", "Q8IBF2", "PF3D7_1037300" ] }, "reaction_10688810": { "compartment": "compartment_70101", "id": "reaction_10688810", "reactome": "R-PFA-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10688805", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:16040", "CHEBI:16235", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17821", "species_83962", "CHEBI:17562", "species_5635947", "species_29850", "CHEBI:17596", "CHEBI:16750", "CHEBI:16235", "CHEBI:16704", "CHEBI:17748", "species_29850", "CHEBI:16335", "CHEBI:17821", "species_83962", "species_5635947", "CHEBI:17562", "CHEBI:16040", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10688808": { "compartment": "compartment_70101", "id": "reaction_10688808", "reactome": "R-PFA-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10688805", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16235", "CHEBI:16704", "CHEBI:17748", "species_29850", "CHEBI:16335", "CHEBI:17821", "species_83962", "species_5635947", "CHEBI:17562", "CHEBI:16040", "CHEBI:16335", "CHEBI:16040", "CHEBI:16235", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17821", "species_83962", "CHEBI:17562", "species_5635947", "species_29850", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10692584": { "compartment": "compartment_70101", "id": "reaction_10692584", "reactome": "R-PFA-727740", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727774" ], "products": [ "species_727737" ], "modifiers": [ [ "species_10692581", "catalyst" ] ], "additional_components": [ "species_209789", "CHEBI:16335", "species_209914", "species_380873", "CHEBI:28918", "species_380873", "CHEBI:28918", "CHEBI:16335", "species_209914", "species_209789", "Q8IKE3", "PF3D7_1469400", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10688815": { "compartment": "compartment_70101", "id": "reaction_10688815", "reactome": "R-PFA-109534", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179743" ], "products": [ "species_179737" ], "modifiers": [ [ "species_10688812", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:16335", "CHEBI:17562", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692605": { "compartment": "compartment_70101", "id": "reaction_10692605", "reactome": "R-PFA-727768", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727737" ], "products": [ "species_727774" ], "modifiers": [ [ "species_10692581", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:16335", "species_209914", "species_209789", "species_209789", "CHEBI:16335", "species_209914", "species_380873", "CHEBI:28918", "Q8IKE3", "PF3D7_1469400", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692601": { "compartment": "compartment_20699", "id": "reaction_10692601", "reactome": "R-PFA-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10692598", "catalyst" ] ], "additional_components": [ "PF3D7_1036800" ] }, "reaction_10703281": { "compartment": "compartment_70101", "id": "reaction_10703281", "reactome": "R-PFA-8981574", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10691617": { "compartment": "compartment_876", "id": "reaction_10691617", "reactome": "R-PFA-428779", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428819" ], "products": [ "species_428802" ], "modifiers": [ [ "species_10691614", "catalyst" ] ], "additional_components": [ "species_70115", "species_29532", "species_70115", "species_29532", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692151": { "compartment": "compartment_70101", "id": "reaction_10692151", "reactome": "R-PFA-450092", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692147" ], "products": [ "species_113592", "species_10692145" ], "modifiers": [], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "species_29358", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10696565": { "compartment": "compartment_70101", "id": "reaction_10696565", "reactome": "R-PFA-5339524", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10692145", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692149": { "compartment": "compartment_70101", "id": "reaction_10692149", "reactome": "R-PFA-450088", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10692145" ], "products": [ "species_10692147" ], "modifiers": [], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "species_29358" ] }, "reaction_10703268": { "compartment": "compartment_70101", "id": "reaction_10703268", "reactome": "R-PFA-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703265", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692154": { "compartment": "compartment_70101", "id": "reaction_10692154", "reactome": "R-PFA-450095", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10691626": { "compartment": "compartment_876", "id": "reaction_10691626", "reactome": "R-PFA-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10691623", "catalyst" ] ], "additional_components": [ "species_70115", "species_30034", "species_29532", "species_70115", "species_30034", "species_29532", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10703279": { "compartment": "compartment_70101", "id": "reaction_10703279", "reactome": "R-PFA-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703276", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10703263": { "compartment": "compartment_70101", "id": "reaction_10703263", "reactome": "R-PFA-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703260", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10698311": { "compartment": "compartment_70101", "id": "reaction_10698311", "reactome": "R-PFA-5690873", "name": "ACO1 binds 4Fe-4S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690881", "species_10698307" ], "products": [ "species_10698309" ], "modifiers": [], "additional_components": [ "PF3D7_1342100", "Q8IDR8", "PF3D7_1342100" ] }, "reaction_10692748": { "compartment": "compartment_74700", "id": "reaction_10692748", "reactome": "R-PFA-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_70106", "species_113592" ], "products": [ "species_29372", "species_29370", "species_74722" ], "modifiers": [ [ "species_10688527", "catalyst" ] ], "additional_components": [ "C0H4P0", "PF3D7_0721900", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8IDF7", "PF3D7_1354400", "Q8IKJ0", "PF3D7_1464700", "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10698318": { "compartment": "compartment_70101", "id": "reaction_10698318", "reactome": "R-PFA-5690911", "name": "ACO1:4Fe-4S isomerises CIT to ISCIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76190" ], "products": [ "species_389545" ], "modifiers": [ [ "species_10698309", "catalyst" ] ], "additional_components": [ "Q8IDR8", "PF3D7_1342100" ] }, "reaction_10698349": { "compartment": "compartment_70101", "id": "reaction_10698349", "reactome": "R-PFA-5691108", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698313", "species_10686740" ], "products": [ "species_10698340" ], "modifiers": [ [ "species_10698346", "catalyst" ] ], "additional_components": [ "PF3D7_1342100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1342100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "Q8IEI4", "PF3D7_1313000" ] }, "reaction_10692878": { "compartment": "compartment_70101", "id": "reaction_10692878", "reactome": "R-PFA-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10692873" ], "products": [ "species_10692875", "species_29370" ], "modifiers": [ [ "species_10692873", "catalyst" ] ], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500" ] }, "reaction_10697478": { "compartment": "compartment_7660", "id": "reaction_10697478", "reactome": "R-PFA-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697474" ], "products": [ "species_10697476" ], "modifiers": [], "additional_components": [ "PF3D7_1423600", "Q8ILL6", "PF3D7_1423600" ] }, "reaction_10697486": { "compartment": "compartment_7660", "id": "reaction_10697486", "reactome": "R-PFA-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10697476" ], "products": [ "species_113582", "species_10697483" ], "modifiers": [ [ "species_10697476", "catalyst" ] ], "additional_components": [ "Q8ILL6", "PF3D7_1423600", "PF3D7_1423600", "Q8ILL6", "PF3D7_1423600" ] }, "reaction_10689771": { "compartment": "compartment_70101", "id": "reaction_10689771", "reactome": "R-PFA-174159", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10689766" ], "products": [ "species_10689768" ], "modifiers": [ [ "species_10689762", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000" ] }, "reaction_10689773": { "compartment": "compartment_70101", "id": "reaction_10689773", "reactome": "R-PFA-174203", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689768" ], "products": [ "species_10686740", "species_10689729", "species_10689762" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1026400", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10686942": { "compartment": "compartment_7660", "id": "reaction_10686942", "reactome": "R-PFA-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_10686458", "species_30185", "species_29892", "species_29604" ], "products": [ "species_10686939" ], "modifiers": [ [ "species_10686433", "catalyst" ] ], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10686461": { "compartment": "compartment_7660", "id": "reaction_10686461", "reactome": "R-PFA-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686456", "species_30595" ], "products": [ "species_10686458", "species_10686452" ], "modifiers": [ [ "species_10686456", "catalyst" ] ], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10688544": { "compartment": "compartment_13231", "id": "reaction_10688544", "reactome": "R-PFA-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688540" ], "products": [ "species_10688542" ], "modifiers": [], "additional_components": [ "PF3D7_0704700", "PF3D7_0704700" ] }, "reaction_10688548": { "compartment": "compartment_70101", "id": "reaction_10688548", "reactome": "R-PFA-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688546" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IC23", "PF3D7_0704700", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10689779": { "compartment": "compartment_13231", "id": "reaction_10689779", "reactome": "R-PFA-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689722" ], "products": [ "species_10689741" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900" ] }, "reaction_10689952": { "compartment": "compartment_7660", "id": "reaction_10689952", "reactome": "R-PFA-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10689775" ], "products": [ "species_113582", "species_10689777" ], "modifiers": [ [ "species_10686575", "catalyst" ] ], "additional_components": [ "PF3D7_1026400", "PF3D7_1026400", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10689724": { "compartment": "compartment_70101", "id": "reaction_10689724", "reactome": "R-PFA-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687085", "species_10689716" ], "products": [ "species_10689722" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10696324": { "compartment": "compartment_13231", "id": "reaction_10696324", "reactome": "R-PFA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10695746", "catalyst" ] ], "additional_components": [ "O77317", "PF3D7_0303200" ] }, "reaction_10694673": { "compartment": "compartment_7660", "id": "reaction_10694673", "reactome": "R-PFA-2288097", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694648", "species_10694615" ], "products": [ "species_10694667" ], "modifiers": [ [ "species_10694671", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600" ] }, "reaction_10694709": { "compartment": "compartment_7660", "id": "reaction_10694709", "reactome": "R-PFA-2301205", "name": "SETD8 monomethylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694658" ], "products": [ "species_77502", "species_10694654" ], "modifiers": [ [ "species_10694706", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067", "PF3D7_0403900" ] }, "reaction_10694661": { "compartment": "compartment_7660", "id": "reaction_10694661", "reactome": "R-PFA-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694654", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10694658" ], "modifiers": [ [ "species_10694654", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067" ] }, "reaction_10694699": { "compartment": "compartment_7660", "id": "reaction_10694699", "reactome": "R-PFA-2294580", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10694683" ], "products": [ "species_113582", "species_10694696" ], "modifiers": [ [ "species_10694683", "catalyst" ] ], "additional_components": [ "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000" ] }, "reaction_10694841": { "compartment": "compartment_70101", "id": "reaction_10694841", "reactome": "R-PFA-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10694807" ], "products": [ "species_10694797", "species_29370" ], "modifiers": [ [ "species_10694838", "catalyst" ] ], "additional_components": [ "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8I413", "PF3D7_0509100", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I413", "PF3D7_0509100", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200", "Q8IDR5", "PF3D7_1342400" ] }, "reaction_10694809": { "compartment": "compartment_70101", "id": "reaction_10694809", "reactome": "R-PFA-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694797", "species_29356" ], "products": [ "species_29372", "species_10694807" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I413", "PF3D7_0509100", "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8I413", "PF3D7_0509100", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100" ] }, "reaction_10689490": { "compartment": "compartment_13231", "id": "reaction_10689490", "reactome": "R-PFA-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687093" ], "products": [ "species_10687099" ], "modifiers": [], "additional_components": [ "Q8IC23", "PF3D7_0704700", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900" ] }, "reaction_10687095": { "compartment": "compartment_70101", "id": "reaction_10687095", "reactome": "R-PFA-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687085", "species_10687091" ], "products": [ "species_10687093" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IC23", "PF3D7_0704700", "Q8IC23", "PF3D7_0704700", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10689368": { "compartment": "compartment_7660", "id": "reaction_10689368", "reactome": "R-PFA-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686939" ], "products": [ "species_113656", "species_10686433" ], "modifiers": [], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10686946": { "compartment": "compartment_7660", "id": "reaction_10686946", "reactome": "R-PFA-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686452", "species_68419" ], "products": [ "species_10686454" ], "modifiers": [], "additional_components": [ "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10686463": { "compartment": "compartment_7660", "id": "reaction_10686463", "reactome": "R-PFA-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686454", "species_10686433" ], "products": [ "species_10686456" ], "modifiers": [], "additional_components": [ "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10702067": { "compartment": "compartment_70101", "id": "reaction_10702067", "reactome": "R-PFA-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702063", "species_10702058" ], "products": [ "species_10702065" ], "modifiers": [], "additional_components": [ "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200" ] }, "reaction_10702090": { "compartment": "compartment_70101", "id": "reaction_10702090", "reactome": "R-PFA-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10702065" ], "products": [ "species_10702087" ], "modifiers": [ [ "species_10702065", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200", "O77328", "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200" ] }, "reaction_10702092": { "compartment": "compartment_70101", "id": "reaction_10702092", "reactome": "R-PFA-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702087" ], "products": [ "species_10702058", "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "O77328", "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10690786": { "compartment": "compartment_70101", "id": "reaction_10690786", "reactome": "R-PFA-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10690778" ], "products": [ "species_29420", "species_10690709" ], "modifiers": [ [ "species_10690783", "catalyst" ] ], "additional_components": [ "Q8I1S0", "PF3D7_0416800", "species_29420", "Q8I1S0", "PF3D7_0416800", "species_29438", "PF3D7_1116400" ] }, "reaction_10698657": { "compartment": "compartment_12045", "id": "reaction_10698657", "reactome": "R-PFA-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690764", "species_10690794", "species_10690709" ], "products": [ "species_10690766" ], "modifiers": [], "additional_components": [ "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29438", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698560": { "compartment": "compartment_13959", "id": "reaction_10698560", "reactome": "R-PFA-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10698553" ], "products": [ "species_10698557", "species_29420" ], "modifiers": [ [ "species_10698553", "catalyst" ] ], "additional_components": [ "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100" ] }, "reaction_10701589": { "compartment": "compartment_6791047", "id": "reaction_10701589", "reactome": "R-PFA-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701211", "species_10701585" ], "products": [ "species_10701587" ], "modifiers": [], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "PF3D7_0323100", "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438" ] }, "reaction_10698660": { "compartment": "compartment_70101", "id": "reaction_10698660", "reactome": "R-PFA-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690766" ], "products": [ "species_10690764", "species_29372", "species_10690794", "species_10690778" ], "modifiers": [ [ "species_10690766", "catalyst" ] ], "additional_components": [ "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29420", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698616": { "compartment": "compartment_6791047", "id": "reaction_10698616", "reactome": "R-PFA-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10698612" ], "products": [ "species_10698614" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "O97323", "PF3D7_0320100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IJ69", "PF3D7_1034000", "O97323", "PF3D7_0320100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IJ69", "PF3D7_1034000", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701592": { "compartment": "compartment_6791047", "id": "reaction_10701592", "reactome": "R-PFA-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701587" ], "products": [ "species_10698448", "species_10701585" ], "modifiers": [ [ "species_10701587", "catalyst" ] ], "additional_components": [ "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "PF3D7_0323100", "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438" ] }, "reaction_10698620": { "compartment": "compartment_13959", "id": "reaction_10698620", "reactome": "R-PFA-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698508", "species_10698551", "species_10698448" ], "products": [ "species_10698553" ], "modifiers": [], "additional_components": [ "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100" ] }, "reaction_10694722": { "compartment": "compartment_5460", "id": "reaction_10694722", "reactome": "R-PFA-2395512", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694718", "species_10693606" ], "products": [ "species_10693598", "species_113529", "species_10694720" ], "modifiers": [], "additional_components": [ "species_31649", "Q8IHW9", "PF3D7_1139700", "Q8I5R0", "PF3D7_1214600", "CHEBI:33737", "CHEBI:33738", "Q8I5R0", "PF3D7_1214600", "species_29386", "Q8IHW9", "PF3D7_1139700" ] }, "reaction_10694724": { "compartment": "compartment_5460", "id": "reaction_10694724", "reactome": "R-PFA-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_10694720", "species_113600" ], "products": [ "species_10694718", "species_113563" ], "modifiers": [], "additional_components": [ "species_29386", "Q8IHW9", "PF3D7_1139700", "species_31649", "Q8IHW9", "PF3D7_1139700" ] }, "reaction_10695704": { "compartment": "compartment_7660", "id": "reaction_10695704", "reactome": "R-PFA-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10694930" ], "products": [ "species_10695702", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695676": { "compartment": "compartment_7660", "id": "reaction_10695676", "reactome": "R-PFA-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695666" ], "products": [ "species_10695674", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1360700", "Q8I444", "PF3D7_0505800", "A0A5K1K9G1", "PF3D7_1360700", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10703252": { "compartment": "compartment_984", "id": "reaction_10703252", "reactome": "R-PFA-8979996", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10703249", "catalyst" ] ], "additional_components": [] }, "reaction_10688609": { "compartment": "compartment_70101", "id": "reaction_10688609", "reactome": "R-PFA-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_75970", "species_73473" ], "products": [ "species_76114", "species_29360" ], "modifiers": [ [ "species_10688606", "catalyst" ] ], "additional_components": [ "Q8IIL4", "PF3D7_1114800", "Q8I5P5", "PF3D7_1216200" ] }, "reaction_10702964": { "compartment": "compartment_5460", "id": "reaction_10702964", "reactome": "R-PFA-8878654", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878649", "species_113521" ], "products": [ "species_113548", "species_8934414" ], "modifiers": [ [ "species_10702961", "catalyst" ] ], "additional_components": [ "PF3D7_0208400" ] }, "reaction_10688574": { "compartment": "compartment_12045", "id": "reaction_10688574", "reactome": "R-PFA-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_426755", "species_76194" ], "modifiers": [ [ "species_10688571", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700", "Q8IL28", "PF3D7_1444300" ] }, "reaction_10699324": { "compartment": "compartment_70101", "id": "reaction_10699324", "reactome": "R-PFA-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10699321", "catalyst" ] ], "additional_components": [ "Q8IAY0", "PF3D7_0814400" ] }, "reaction_10692323": { "compartment": "compartment_876", "id": "reaction_10692323", "reactome": "R-PFA-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692305" ], "products": [ "species_10692321" ], "modifiers": [], "additional_components": [ "Q8IBM9", "PF3D7_0722400", "Q7KQL9", "PF14_0425", "Q8I509", "PF3D7_1242000", "Q8I563", "PF3D7_1448600", "Q8IKY7", "PF3D7_1448600", "O96268", "PF3D7_0219100", "Q7KQL9", "PF14_0425", "Q8IBM9", "PF3D7_0722400", "Q8I509", "PF3D7_1242000", "O96268", "PF3D7_0219100", "Q8IKY7", "PF3D7_1448600", "Q8I563", "PF3D7_1448600" ] }, "reaction_10692394": { "compartment": "compartment_70101", "id": "reaction_10692394", "reactome": "R-PFA-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692370" ], "products": [ "species_10692392" ], "modifiers": [], "additional_components": [ "Q8I2G8", "PF3D7_0935200", "C6KSX9", "PF3D7_0935200", "Q8IFP3", "PF3D7_0903700", "Q6ZLZ9", "PF3D7_0903700", "Q8ILW9", "PF3D7_1246200", "Q8I4X0", "PF3D7_1246200", "P62203", "PF14_0323", "Q8ILW9", "PF3D7_1246200", "Q8I4X0", "PF3D7_1246200", "C6KSX9", "PF3D7_0935200", "Q8I2G8", "PF3D7_0935200", "P62203", "PF14_0323", "Q8IFP3", "PF3D7_0903700", "Q6ZLZ9", "PF3D7_0903700" ] }, "reaction_10692329": { "compartment": "compartment_876", "id": "reaction_10692329", "reactome": "R-PFA-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692325" ], "products": [ "species_10692327" ], "modifiers": [], "additional_components": [ "PF3D7_1367500", "PF3D7_1367500" ] }, "reaction_10688412": { "compartment": "compartment_70101", "id": "reaction_10688412", "reactome": "R-PFA-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500430" ], "products": [ "species_83962", "species_500244" ], "modifiers": [ [ "species_10688407", "catalyst" ] ], "additional_components": [ "CHEBI:16450", "CHEBI:16704", "CHEBI:28542", "species_112016", "Q8I3X4", "PF3D7_0513300" ] }, "reaction_10703354": { "compartment": "compartment_70101", "id": "reaction_10703354", "reactome": "R-PFA-9018895", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023653", "species_29450" ], "products": [ "species_29356", "species_9023651", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10703352": { "compartment": "compartment_70101", "id": "reaction_10703352", "reactome": "R-PFA-9018868", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9020583", "species_29450" ], "products": [ "species_29356", "species_9020474", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10692893": { "compartment": "compartment_70101", "id": "reaction_10692893", "reactome": "R-PFA-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692886" ], "products": [ "species_10692888", "species_10686740" ], "modifiers": [ [ "species_10692890", "catalyst" ] ], "additional_components": [ "PF3D7_1439100", "PF3D7_1439100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PFC1020c" ] }, "reaction_10691191": { "compartment": "compartment_876", "id": "reaction_10691191", "reactome": "R-PFA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691189" ], "products": [ "species_10691189" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "Q8IKI3", "PF3D7_1465500", "Q8I5E6", "PF3D7_1465500", "Q8IKI3", "PF3D7_1465500", "Q8I5E6", "PF3D7_1465500", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10692412": { "compartment": "compartment_876", "id": "reaction_10692412", "reactome": "R-PFA-499981", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10692409", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10687135": { "compartment": "compartment_70101", "id": "reaction_10687135", "reactome": "R-PFA-70342", "name": "ALDOB tetramer cleaves Fru-1-P to GA and DHAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31221" ], "products": [ "species_30393", "species_75970" ], "modifiers": [ [ "species_10687132", "catalyst" ] ], "additional_components": [ "Q7KQL9", "PF14_0425" ] }, "reaction_10702809": { "compartment": "compartment_70101", "id": "reaction_10702809", "reactome": "R-PFA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10702806", "catalyst" ] ], "additional_components": [ "PF3D7_0309300" ] }, "reaction_10687203": { "compartment": "compartment_70101", "id": "reaction_10687203", "reactome": "R-PFA-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10687198", "catalyst" ] ], "additional_components": [ "Q8ILA4", "PF3D7_1436000" ] }, "reaction_10687522": { "compartment": "compartment_5460", "id": "reaction_10687522", "reactome": "R-PFA-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_29362", "species_113587" ], "products": [ "species_113544", "species_113526" ], "modifiers": [ [ "species_10687371", "catalyst" ] ], "additional_components": [ "Q76NM3", "PF3D7_1324900" ] }, "reaction_10687239": { "compartment": "compartment_70101", "id": "reaction_10687239", "reactome": "R-PFA-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29492" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10687236", "catalyst" ] ], "additional_components": [ "Q8IJN7", "PF10_0155", "species_29926" ] }, "reaction_10687223": { "compartment": "compartment_70101", "id": "reaction_10687223", "reactome": "R-PFA-70486", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29728" ], "products": [ "species_29370", "species_29800" ], "modifiers": [ [ "species_10687220", "catalyst" ] ], "additional_components": [ "species_29926", "P27362", "PFI1105w" ] }, "reaction_10687207": { "compartment": "compartment_70101", "id": "reaction_10687207", "reactome": "R-PFA-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29800", "species_73473" ], "products": [ "species_29372", "species_29578", "species_29360" ], "modifiers": [ [ "species_10687178", "catalyst" ] ], "additional_components": [ "Q8IKK7", "PF3D7_1462800" ] }, "reaction_10687447": { "compartment": "compartment_70101", "id": "reaction_10687447", "reactome": "R-PFA-71495", "name": "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578", "species_75970" ], "products": [ "species_30014" ], "modifiers": [ [ "species_10687132", "catalyst" ] ], "additional_components": [ "Q7KQL9", "PF14_0425" ] }, "reaction_10687205": { "compartment": "compartment_70101", "id": "reaction_10687205", "reactome": "R-PFA-70481", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578" ], "products": [ "species_75970" ], "modifiers": [ [ "species_10687188", "catalyst" ] ], "additional_components": [ "Q7KQM0", "PF14_0378" ] }, "reaction_10687444": { "compartment": "compartment_70101", "id": "reaction_10687444", "reactome": "R-PFA-71445", "name": "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30485" ], "products": [ "species_29728" ], "modifiers": [ [ "species_10687441", "catalyst" ] ], "additional_components": [ "Q8IIG6", "PF3D7_1120100" ] }, "reaction_10687272": { "compartment": "compartment_5460", "id": "reaction_10687272", "reactome": "R-PFA-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_113552" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10689720": { "compartment": "compartment_13231", "id": "reaction_10689720", "reactome": "R-PFA-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689718" ], "products": [ "species_10687154" ], "modifiers": [], "additional_components": [ "PF3D7_0624000", "PF3D7_0624000" ] }, "reaction_10687163": { "compartment": "compartment_70101", "id": "reaction_10687163", "reactome": "R-PFA-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10687160", "catalyst" ] ], "additional_components": [ "C6KT76", "PF3D7_0624000" ] }, "reaction_10687480": { "compartment": "compartment_70101", "id": "reaction_10687480", "reactome": "R-PFA-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10687477", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_29358", "inhibitor" ], [ "species_30389", "inhibitor" ] ], "additional_components": [ "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "species_29926", "species_74126" ] }, "reaction_10703214": { "compartment": "compartment_70101", "id": "reaction_10703214", "reactome": "R-PFA-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29800" ], "products": [ "species_70106", "species_8955759", "species_29728" ], "modifiers": [ [ "species_10687120", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10699884": { "compartment": "compartment_70101", "id": "reaction_10699884", "reactome": "R-PFA-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10699881", "catalyst" ] ], "additional_components": [ "Q8IIG6", "PF3D7_1120100" ] }, "reaction_10688330": { "compartment": "compartment_70101", "id": "reaction_10688330", "reactome": "R-PFA-73646", "name": "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688318", "species_70106", "species_29364" ], "products": [ "species_29366", "species_10688320" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "P61076", "PFI1170c", "species_29386" ] }, "reaction_10687149": { "compartment": "compartment_70101", "id": "reaction_10687149", "reactome": "R-PFA-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29366" ], "products": [ "species_70106", "species_31467", "species_29364" ], "modifiers": [ [ "species_10687146", "catalyst" ] ], "additional_components": [ "species_29366", "Q8IKU0", "PF14_0511" ] }, "reaction_10703102": { "compartment": "compartment_876", "id": "reaction_10703102", "reactome": "R-PFA-8943987", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703094" ], "products": [ "species_10703100" ], "modifiers": [], "additional_components": [ "C0H518", "PF3D7_1208200", "A0A5K1K8N7", "PF3D7_1208200", "C0H518", "PF3D7_1208200", "A0A5K1K8N7", "PF3D7_1208200" ] }, "reaction_10698562": { "compartment": "compartment_12045", "id": "reaction_10698562", "reactome": "R-PFA-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690729", "species_10690727", "species_10690721" ], "products": [ "species_10690731" ], "modifiers": [], "additional_components": [ "PF3D7_0822600", "C0H489", "PF3D7_0405100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10698618": { "compartment": "compartment_12045", "id": "reaction_10698618", "reactome": "R-PFA-5694428", "name": "LMAN family proteins bind glycosylated cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690760", "species_10690746" ], "products": [ "species_10690762" ], "modifiers": [], "additional_components": [ "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8I2A1", "PF3D7_0103900", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698568": { "compartment": "compartment_12045", "id": "reaction_10698568", "reactome": "R-PFA-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690729", "species_10690665", "species_10698564" ], "products": [ "species_10698566" ], "modifiers": [], "additional_components": [ "PF3D7_0822600", "PF3D7_0320100", "C0H5J6", "PF3D7_1361100", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10694553": { "compartment": "compartment_70101", "id": "reaction_10694553", "reactome": "R-PFA-2161961", "name": "EET(1) is hydrolysed to DHET(1) by EPHX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2161818" ], "products": [ "species_2161883" ], "modifiers": [ [ "species_10694550", "catalyst" ] ], "additional_components": [ "CHEBI:34450", "CHEBI:34130", "CHEBI:34490", "CHEBI:34157", "CHEBI:63974", "CHEBI:63969", "CHEBI:63970", "CHEBI:63966", "species_29926", "Q8IM75", "PF3D7_1401300" ] }, "reaction_10703339": { "compartment": "compartment_5460", "id": "reaction_10703339", "reactome": "R-PFA-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703402": { "compartment": "compartment_5460", "id": "reaction_10703402", "reactome": "R-PFA-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_10703333" ], "products": [ "species_10703400", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400", "PF3D7_1206400", "PF3D7_1206400" ] }, "reaction_10703336": { "compartment": "compartment_5460", "id": "reaction_10703336", "reactome": "R-PFA-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703343": { "compartment": "compartment_5460", "id": "reaction_10703343", "reactome": "R-PFA-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703341": { "compartment": "compartment_5460", "id": "reaction_10703341", "reactome": "R-PFA-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703132": { "compartment": "compartment_70101", "id": "reaction_10703132", "reactome": "R-PFA-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698288" ], "products": [ "species_10698286", "species_10698177" ], "modifiers": [], "additional_components": [ "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "PF3D7_1313000", "PF3D7_1460400" ] }, "reaction_10692793": { "compartment": "compartment_70101", "id": "reaction_10692793", "reactome": "R-PFA-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692761", "species_10692789" ], "products": [ "species_10692791" ], "modifiers": [], "additional_components": [ "PF3D7_1005500", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IIC9", "PF3D7_1123400", "species_29420", "O96203", "PF3D7_0212300", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IIC9", "PF3D7_1123400", "species_29420", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500" ] }, "reaction_10690540": { "compartment": "compartment_70101", "id": "reaction_10690540", "reactome": "R-PFA-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10690537", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10692468": { "compartment": "compartment_70101", "id": "reaction_10692468", "reactome": "R-PFA-514604", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113578", "species_29364" ], "products": [ "species_29366", "species_29602", "species_31633" ], "modifiers": [ [ "species_10692465", "catalyst" ] ], "additional_components": [ "Q8I2U5", "PF3D7_0920800" ] }, "reaction_10688719": { "compartment": "compartment_70101", "id": "reaction_10688719", "reactome": "R-PFA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10688716", "catalyst" ] ], "additional_components": [ "Q8IE53", "PF3D7_1329400" ] }, "reaction_10688380": { "compartment": "compartment_70101", "id": "reaction_10688380", "reactome": "R-PFA-74215", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_500259" ], "products": [ "species_111294", "species_500260" ], "modifiers": [ [ "species_10688377", "catalyst" ] ], "additional_components": [ "CHEBI:16235", "species_29850", "species_29602", "species_113578", "Q8IJS1", "PF3D7_1012400", "species_29926" ] }, "reaction_10688396": { "compartment": "compartment_70101", "id": "reaction_10688396", "reactome": "R-PFA-74241", "name": "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH4+ (ADA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500173" ], "products": [ "species_500172", "species_31633" ], "modifiers": [ [ "species_10688393", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17256", "CHEBI:28997", "CHEBI:17596", "PF3D7_1029600" ] }, "reaction_10702565": { "compartment": "compartment_70101", "id": "reaction_10702565", "reactome": "R-PFA-8870457", "name": "FarC-PTP4A2 binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702559", "species_10702561" ], "products": [ "species_10702563" ], "modifiers": [], "additional_components": [ "PF3D7_1113100", "PF3D7_0602500", "C6KSM5", "PF3D7_0602500", "Q8IIN1", "PF3D7_1113100" ] }, "reaction_10702571": { "compartment": "compartment_70101", "id": "reaction_10702571", "reactome": "R-PFA-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702567", "species_10702561" ], "products": [ "species_10702569" ], "modifiers": [ [ "species_10702563", "inhibitor" ] ], "additional_components": [ "PF3D7_1442500", "PF3D7_0602500", "C6KSM5", "PF3D7_0602500", "Q8IL46", "PF3D7_1442500", "C6KSM5", "PF3D7_0602500", "Q8IIN1", "PF3D7_1113100" ] }, "reaction_10688826": { "compartment": "compartment_876", "id": "reaction_10688826", "reactome": "R-PFA-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10688822" ], "products": [ "species_10688824" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "Q8IIE7", "PF3D7_1121900", "species_179838" ] }, "reaction_10701191": { "compartment": "compartment_5460", "id": "reaction_10701191", "reactome": "R-PFA-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10701188", "catalyst" ] ], "additional_components": [ "Q8IKN4", "PF14_0570" ] }, "reaction_10690276": { "compartment": "compartment_70101", "id": "reaction_10690276", "reactome": "R-PFA-197186", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197230", "species_70106" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10690273", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "C6KTC6", "PF3D7_0629100" ] }, "reaction_10702553": { "compartment": "compartment_876", "id": "reaction_10702553", "reactome": "R-PFA-8869603", "name": "SLC22A13 transports NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8869604" ], "products": [ "species_197230" ], "modifiers": [ [ "species_10692518", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10701199": { "compartment": "compartment_5460", "id": "reaction_10701199", "reactome": "R-PFA-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6807477" ], "products": [ "species_113548", "species_113581", "species_113529", "species_113600" ], "modifiers": [ [ "species_10701196", "catalyst" ] ], "additional_components": [ "PF3D7_1143900" ] }, "reaction_10703211": { "compartment": "compartment_5460", "id": "reaction_10703211", "reactome": "R-PFA-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113526" ], "products": [ "species_113581", "species_113563", "species_113529" ], "modifiers": [ [ "species_10703208", "catalyst" ] ], "additional_components": [ "Q8I319", "PF3D7_0913300" ] }, "reaction_10690286": { "compartment": "compartment_70101", "id": "reaction_10690286", "reactome": "R-PFA-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_197256", "species_113592", "species_29472" ], "products": [ "species_111294", "species_29404", "species_76577", "species_29360" ], "modifiers": [ [ "species_10690283", "catalyst" ] ], "additional_components": [ "Q8I2P2", "PF3D7_0926700" ] }, "reaction_10690218": { "compartment": "compartment_70101", "id": "reaction_10690218", "reactome": "R-PFA-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196095", "species_70106", "species_29364" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10690215", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10703665": { "compartment": "compartment_70101", "id": "reaction_10703665", "reactome": "R-PFA-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10695751", "catalyst" ] ], "additional_components": [ "PF3D7_1455900" ] }, "reaction_10698686": { "compartment": "compartment_5460", "id": "reaction_10698686", "reactome": "R-PFA-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_5696835" ], "products": [ "species_113529", "species_5696848", "species_113600" ], "modifiers": [ [ "species_10698683", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10696894": { "compartment": "compartment_70101", "id": "reaction_10696894", "reactome": "R-PFA-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696892", "species_29438" ], "products": [ "species_29420", "species_10696890" ], "modifiers": [ [ "species_10690962", "catalyst" ] ], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q7KQL3", "PF10_0203", "species_29438", "PF3D7_1442900" ] }, "reaction_10690946": { "compartment": "compartment_70101", "id": "reaction_10690946", "reactome": "R-PFA-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10690943", "catalyst" ] ], "additional_components": [ "PF3D7_1033100" ] }, "reaction_10686402": { "compartment": "compartment_7660", "id": "reaction_10686402", "reactome": "R-PFA-68611", "name": "Orc1 associates with Orc4:Orc5:Orc3:Orc2:origin complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686398", "species_10686393" ], "products": [ "species_10686400" ], "modifiers": [], "additional_components": [ "PF3D7_1203000", "Q8IC17", "PF3D7_0705300", "O96237", "PF3D7_0215800", "A0A5K1K8V1", "PF3D7_1334100", "Q8IC17", "PF3D7_0705300", "O96237", "PF3D7_0215800", "A0A5K1K8V1", "PF3D7_1334100", "Q8I615", "PF3D7_1203000" ] }, "reaction_10686409": { "compartment": "compartment_7660", "id": "reaction_10686409", "reactome": "R-PFA-68637", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10686407" ], "modifiers": [], "additional_components": [ "PF3D7_0503200" ] }, "reaction_10692172": { "compartment": "compartment_70101", "id": "reaction_10692172", "reactome": "R-PFA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692164" ], "products": [ "species_10692170" ], "modifiers": [], "additional_components": [ "Q8IBK6", "PF3D7_0724600", "Q8IBK6", "PF3D7_0724600" ] }, "reaction_10693514": { "compartment": "compartment_70101", "id": "reaction_10693514", "reactome": "R-PFA-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693510" ], "products": [ "species_10693512" ], "modifiers": [], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "CHEBI:60627", "CHEBI:60628", "CHEBI:59092", "CHEBI:60629", "CHEBI:59087", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10694711": { "compartment": "compartment_70101", "id": "reaction_10694711", "reactome": "R-PFA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_179838" ], "products": [ "species_10688824" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "Q8IIE7", "PF3D7_1121900", "species_179838" ] }, "reaction_10693565": { "compartment": "compartment_70101", "id": "reaction_10693565", "reactome": "R-PFA-1250280", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688320", "species_1250243" ], "products": [ "species_10688318" ], "modifiers": [], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500" ] }, "reaction_10700704": { "compartment": "compartment_6799351", "id": "reaction_10700704", "reactome": "R-PFA-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700690" ], "products": [ "species_10700702" ], "modifiers": [], "additional_components": [ "Q8IDS0", "PF3D7_1341900", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8II31", "PF3D7_1133300", "Q8IJB1", "PF3D7_1133300", "O97295", "PF3D7_0322300", "C0H5C6", "PF3D7_1320500", "Q8ILE6", "PF3D7_1431900", "Q7KWJ5", "PF3D7_0919500", "Q8IL28", "PF3D7_1444300", "Q8IDL8", "PF3D7_1348100", "Q8I2V8", "PF3D7_0919500", "Q8IEK4", "PF3D7_1311400", "Q8I4T2", "PF3D7_1250200", "Q8I4U9", "PF3D7_1248500", "Q8I5L4", "PF3D7_1468600", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILE6", "PF3D7_1431900", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500", "Q8IEK4", "PF3D7_1311400", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IL28", "PF3D7_1444300", "Q8I4U9", "PF3D7_1248500", "Q8IDL8", "PF3D7_1348100", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "O97295", "PF3D7_0322300", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10700208": { "compartment": "compartment_6799713", "id": "reaction_10700208", "reactome": "R-PFA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700192" ], "products": [ "species_10700206" ], "modifiers": [], "additional_components": [ "Q8I3R7", "PF3D7_0519200", "Q7KWJ5", "PF3D7_0919500", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILG6", "PF3D7_1429800", "Q8I3M7", "PF3D7_0523800", "Q8I5R9", "PF3D7_1357300", "Q8IBG2", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILG6", "PF3D7_1429800", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q7KWJ5", "PF3D7_0919500", "Q8I3R7", "PF3D7_0519200", "Q8I3M7", "PF3D7_0523800" ] }, "reaction_10700629": { "compartment": "compartment_1470028", "id": "reaction_10700629", "reactome": "R-PFA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700591" ], "products": [ "species_10700627" ], "modifiers": [], "additional_components": [ "Q8IM42", "PF3D7_1405200", "O96220", "PF3D7_0214000", "Q7KQL5", "PF10_0084", "C6KT34", "PF3D7_0619400", "Q8IKH3", "PF3D7_1466300", "C6KSW6", "PF3D7_0822500", "Q8I412", "PF3D7_0822500", "Q8IB59", "PF3D7_0822500", "Q8IAM2", "PF3D7_0802200", "Q8I1V9", "PF3D7_0409900", "C6KTC6", "PF3D7_0629100", "Q8I384", "PF3D7_0906500", "Q8ID33", "PF3D7_1367500", "Q8ILI2", "PF3D7_1428300", "Q8IM55", "PF3D7_1403900", "Q8I501", "PF3D7_1242800", "O96166", "PF3D7_0207900", "O97247", "PF3D7_0306800", "Q8I2H1", "PF3D7_0934700", "Q8ID33", "PF3D7_1367500", "Q8I384", "PF3D7_0906500", "C6KSW6", "PF3D7_0822500", "Q8IB59", "PF3D7_0822500", "Q8I412", "PF3D7_0822500", "Q8ILI2", "PF3D7_1428300", "C6KTC6", "PF3D7_0629100", "Q8IM42", "PF3D7_1405200", "C6KT34", "PF3D7_0619400", "O97247", "PF3D7_0306800", "O96220", "PF3D7_0214000", "Q7KQL5", "PF10_0084", "Q8IKH3", "PF3D7_1466300", "Q8IAM2", "PF3D7_0802200", "Q8I501", "PF3D7_1242800", "Q8I1V9", "PF3D7_0409900", "O96166", "PF3D7_0207900", "Q8IM55", "PF3D7_1403900", "Q8I2H1", "PF3D7_0934700" ] }, "reaction_10700075": { "compartment": "compartment_876", "id": "reaction_10700075", "reactome": "R-PFA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700049" ], "products": [ "species_10700073" ], "modifiers": [], "additional_components": [ "C6KT12", "PF3D7_1246300", "Q7K6B0", "PF3D7_0807300", "Q76NM7", "PF3D7_1310600", "Q7KWJ5", "PF3D7_0919500", "O97278", "PF3D7_0319700", "Q8ILG6", "PF3D7_1429800", "Q8I274", "PF3D7_0211200", "C0H516", "PF3D7_0903200", "Q8IHR8", "PF3D7_1144900", "Q8IAQ8", "PF3D7_0806800", "C0H4M1", "PF3D7_0707400", "Q8I385", "PF3D7_0906400", "Q8I274", "PF3D7_0211200", "O97278", "PF3D7_0319700", "Q76NM7", "PF3D7_1310600", "C0H516", "PF3D7_0903200", "Q8IHR8", "PF3D7_1144900", "Q7KWJ5", "PF3D7_0919500", "C6KT12", "PF3D7_1246300", "C0H4M1", "PF3D7_0707400", "Q8ILG6", "PF3D7_1429800", "Q8I385", "PF3D7_0906400", "Q8IAQ8", "PF3D7_0806800", "Q7K6B0", "PF3D7_0807300" ] }, "reaction_10700489": { "compartment": "compartment_1462052", "id": "reaction_10700489", "reactome": "R-PFA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700371" ], "products": [ "species_10700487" ], "modifiers": [], "additional_components": [ "Q8IL68", "PF3D7_1440300", "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "Q8IE53", "PF3D7_1329400", "C0H568", "PF3D7_0927500", "Q8IBH5", "PF3D7_1110700", "A0A143ZXR3", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8I0P6", "PF3D7_1357000", "Q8IB94", "PF3D7_0826100", "Q7KQL9", "PF14_0425", "Q8IIA3", "PF3D7_1126100", "Q8IKW5", "PF3D7_1451100", "Q8IAU1", "PF3D7_0810600", "Q8ILA4", "PF3D7_1436000", "Q8I323", "PF3D7_0912900", "Q8IJS0", "PF3D7_1012500", "Q8IDR5", "PF3D7_1342400", "Q8IC05", "PF3D7_1443900", "A0A5K1K9F3", "PF3D7_1338100", "Q8IB24", "PF3D7_0818900", "Q8II71", "PF3D7_1129200", "Q8ID28", "PF3D7_1368100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "O96153", "PF3D7_0205900", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IJM0", "PF3D7_1017900", "Q8IJA0", "PF3D7_1030500", "Q8I616", "PF3D7_1202900", "Q8IEK3", "PF3D7_1311500", "C6KT76", "PF3D7_0624000", "Q8IM66", "PF3D7_1402300", "C6KST3", "PF3D7_0608500", "Q8I613", "PF3D7_1203200", "Q8I6T3", "PF3D7_1328100", "Q8II60", "PF3D7_1130400", "A0A5K1K7U1", "PF3D7_0518300", "C6KT01", "PF3D7_0616000", "Q8IBI3", "PF3D7_0727400", "C6KT34", "PF3D7_0619400", "O96220", "PF3D7_0214000", "Q8IIG6", "PF3D7_1120100", "Q8ID43", "PF3D7_1366500", "Q8I5C5", "PF3D7_1229400", "Q8I5Q4", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q76NN7", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "Q8I501", "PF3D7_1242800", "Q8IM66", "PF3D7_1402300", "Q8I0P6", "PF3D7_1357000", "Q8IJM0", "PF3D7_1017900", "Q8IB94", "PF3D7_0826100", "Q8I5C5", "PF3D7_1229400", "Q8II60", "PF3D7_1130400", "Q8IJS0", "PF3D7_1012500", "Q8IEK3", "PF3D7_1311500", "Q8IKW5", "PF3D7_1451100", "C6KT34", "PF3D7_0619400", "Q8IB24", "PF3D7_0818900", "Q8I613", "PF3D7_1203200", "Q8ILA4", "PF3D7_1436000", "O96220", "PF3D7_0214000", "C6KT01", "PF3D7_0616000", "Q8IC05", "PF3D7_1443900", "Q8I501", "PF3D7_1242800", "C6KT76", "PF3D7_0624000", "Q8IL32", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "Q8IE53", "PF3D7_1329400", "Q8I6T3", "PF3D7_1328100", "A0A143ZXR3", "PF3D7_1110700", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8I616", "PF3D7_1202900", "Q8IIA3", "PF3D7_1126100", "Q8IBI3", "PF3D7_0727400", "Q8IAU1", "PF3D7_0810600", "C6KST3", "PF3D7_0608500", "Q8ID43", "PF3D7_1366500", "Q8IDR5", "PF3D7_1342400", "A0A5K1K7U1", "PF3D7_0518300", "Q8IIG6", "PF3D7_1120100", "Q76NN7", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "Q7KQL9", "PF14_0425", "Q8II71", "PF3D7_1129200", "Q8I323", "PF3D7_0912900", "O96153", "PF3D7_0205900", "C6KTA4", "PF3D7_1037100", "Q8IJ37", "PF3D7_1037100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "A0A5K1K9F3", "PF3D7_1338100", "Q8IJA0", "PF3D7_1030500", "C0H568", "PF3D7_0927500", "Q8ID28", "PF3D7_1368100", "Q8IL68", "PF3D7_1440300" ] }, "reaction_10700520": { "compartment": "compartment_6799371", "id": "reaction_10700520", "reactome": "R-PFA-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700508" ], "products": [ "species_10700518" ], "modifiers": [], "additional_components": [ "C6KT01", "PF3D7_0616000", "Q8IAY9", "PF3D7_0815200", "Q8I384", "PF3D7_0906500", "Q8I509", "PF3D7_1242000", "Q8I1Y2", "PF3D7_0404700", "Q8I6Z5", "PF3D7_1323500", "Q8I486", "PF3D7_0501400", "Q8I384", "PF3D7_0906500", "Q8I486", "PF3D7_0501400", "Q8I6Z5", "PF3D7_1323500", "Q8I509", "PF3D7_1242000", "Q8I1Y2", "PF3D7_0404700", "Q8IAY9", "PF3D7_0815200", "C6KT01", "PF3D7_0616000" ] }, "reaction_10700136": { "compartment": "compartment_6800173", "id": "reaction_10700136", "reactome": "R-PFA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700108" ], "products": [ "species_10700134" ], "modifiers": [], "additional_components": [ "Q8I509", "PF3D7_1242000", "Q8I2Q2", "PF3D7_0925600", "Q8I6Z5", "PF3D7_1323500", "Q7KQL9", "PF14_0425", "Q8I6U4", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q7KQL9", "PF14_0425", "Q8I6Z5", "PF3D7_1323500", "Q8I509", "PF3D7_1242000", "Q8IIL0", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8I2Q2", "PF3D7_0925600" ] }, "reaction_10700943": { "compartment": "compartment_984", "id": "reaction_10700943", "reactome": "R-PFA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700933" ], "products": [ "species_10700941" ], "modifiers": [], "additional_components": [ "Q8IKW5", "PF3D7_1451100", "C0H568", "PF3D7_0927500", "Q8IB94", "PF3D7_0826100", "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "Q8IL68", "PF3D7_1440300", "Q76NN7", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "A0A5K1K7U1", "PF3D7_0518300", "Q8ID28", "PF3D7_1368100", "Q8ID43", "PF3D7_1366500", "O96153", "PF3D7_0205900", "C6KST3", "PF3D7_0608500", "Q8IJM0", "PF3D7_1017900", "Q8IBI3", "PF3D7_0727400", "Q8IJA0", "PF3D7_1030500", "Q8I616", "PF3D7_1202900", "Q8IEK3", "PF3D7_1311500", "Q8I6T3", "PF3D7_1328100", "Q8IM66", "PF3D7_1402300", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "Q8I613", "PF3D7_1203200", "C6KT76", "PF3D7_0624000", "Q8II60", "PF3D7_1130400", "C6KT34", "PF3D7_0619400", "Q8ILA4", "PF3D7_1436000", "Q8IB24", "PF3D7_0818900", "Q7KQL9", "PF14_0425", "Q8IJS0", "PF3D7_1012500", "Q8IIA3", "PF3D7_1126100", "P62203", "PF14_0323", "Q8IE53", "PF3D7_1329400", "Q8IAU1", "PF3D7_0810600", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "A0A143ZXR3", "PF3D7_1110700", "O97289", "PF3D7_0321500", "Q8I1V9", "PF3D7_0409900", "Q8IAY9", "PF3D7_0815200", "O96220", "PF3D7_0214000", "Q8I323", "PF3D7_0912900", "Q8I2Q2", "PF3D7_0925600", "Q8IIG6", "PF3D7_1120100", "A0A5K1K9F3", "PF3D7_1338100", "Q8I5C5", "PF3D7_1229400", "Q8II71", "PF3D7_1129200", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "Q8I1Y2", "PF3D7_0404700", "Q8I6Z5", "PF3D7_1323500", "Q8IDR5", "PF3D7_1342400", "Q8IIJ9", "PF11_0174", "Q8I0P6", "PF3D7_1357000", "Q8IAY9", "PF3D7_0815200", "Q8IJA0", "PF3D7_1030500", "A0A5K1K9F3", "PF3D7_1338100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "O96153", "PF3D7_0205900", "Q8I323", "PF3D7_0912900", "Q8II71", "PF3D7_1129200", "Q8I6Z5", "PF3D7_1323500", "Q8I1V9", "PF3D7_0409900", "Q7KQL9", "PF14_0425", "Q8I2Q2", "PF3D7_0925600", "Q8IIG6", "PF3D7_1120100", "A0A5K1K7U1", "PF3D7_0518300", "Q8ID43", "PF3D7_1366500", "Q8IAU1", "PF3D7_0810600", "Q8IIA3", "PF3D7_1126100", "A0A143ZXR3", "PF3D7_1110700", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8IE53", "PF3D7_1329400", "O96220", "PF3D7_0214000", "Q8I613", "PF3D7_1203200", "C6KT34", "PF3D7_0619400", "Q8I1Y2", "PF3D7_0404700", "Q8IEK3", "PF3D7_1311500", "Q8II60", "PF3D7_1130400", "Q8I5C5", "PF3D7_1229400", "Q8IJM0", "PF3D7_1017900", "Q8IM66", "PF3D7_1402300", "Q8IL68", "PF3D7_1440300", "C0H568", "PF3D7_0927500", "C6KTA4", "PF3D7_1037100", "Q8IJ37", "PF3D7_1037100", "Q8IIK8", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q76NN7", "PF3D7_1215200", "P62203", "PF14_0323", "Q8IIJ9", "PF11_0174", "O97289", "PF3D7_0321500", "Q8IDR5", "PF3D7_1342400", "C6KST3", "PF3D7_0608500", "Q8IBI3", "PF3D7_0727400", "Q8I616", "PF3D7_1202900", "Q8I6T3", "PF3D7_1328100", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "C6KT76", "PF3D7_0624000", "Q8ILA4", "PF3D7_1436000", "Q8IB24", "PF3D7_0818900", "Q8IKW5", "PF3D7_1451100", "Q8IJS0", "PF3D7_1012500", "Q8IB94", "PF3D7_0826100", "Q8I0P6", "PF3D7_1357000", "Q8ID28", "PF3D7_1368100" ] }, "reaction_10699997": { "compartment": "compartment_6798757", "id": "reaction_10699997", "reactome": "R-PFA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699963" ], "products": [ "species_10699995" ], "modifiers": [], "additional_components": [ "Q8I3R7", "PF3D7_0519200", "Q8IL71", "PF3D7_1439800", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "O97278", "PF3D7_0319700", "Q8I2V7", "PF3D7_0919600", "B9ZSI6", "PF3D7_0107700", "O96171", "PF3D7_0208400", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IDL8", "PF3D7_1348100", "Q8I310", "PF3D7_0914200", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "C0H5C6", "PF3D7_1320500", "Q8I3F8", "PF3D7_0531000", "O96171", "PF3D7_0208400", "Q8I5L4", "PF3D7_1468600", "O97278", "PF3D7_0319700", "Q8I3F8", "PF3D7_0531000", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "Q8I3R7", "PF3D7_0519200", "C0H5C6", "PF3D7_1320500", "Q8IL71", "PF3D7_1439800", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IDL8", "PF3D7_1348100", "Q8I2V7", "PF3D7_0919600", "B9ZSI6", "PF3D7_0107700", "Q8I310", "PF3D7_0914200" ] }, "reaction_10700781": { "compartment": "compartment_6800424", "id": "reaction_10700781", "reactome": "R-PFA-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700769" ], "products": [ "species_10700779" ], "modifiers": [], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I385", "PF3D7_0906400", "C6KT12", "PF3D7_1246300", "Q8IIL9", "PF3D7_1114200", "Q8I379", "PF3D7_1114200", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8ILG6", "PF3D7_1429800", "Q8I3M7", "PF3D7_0523800", "C0H4M1", "PF3D7_0707400", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "C6KT12", "PF3D7_1246300", "C0H4M1", "PF3D7_0707400", "Q8I379", "PF3D7_1114200", "Q8IIL9", "PF3D7_1114200", "Q8ILG6", "PF3D7_1429800", "Q8I385", "PF3D7_0906400", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8IAQ8", "PF3D7_0806800", "Q7KWJ5", "PF3D7_0919500", "Q8I3R7", "PF3D7_0519200", "Q8I3M7", "PF3D7_0523800" ] }, "reaction_10701410": { "compartment": "compartment_984", "id": "reaction_10701410", "reactome": "R-PFA-6810724", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803081", "species_10701406" ], "products": [ "species_10701408" ], "modifiers": [], "additional_components": [ "Q8I486", "PF3D7_0501400", "Q8I486", "PF3D7_0501400", "species_166005" ] }, "reaction_10701031": { "compartment": "compartment_984", "id": "reaction_10701031", "reactome": "R-PFA-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_181015", "species_10701027" ], "products": [ "species_10701029" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "Q8I616", "PF3D7_1202900", "species_181015" ] }, "reaction_10701035": { "compartment": "compartment_984", "id": "reaction_10701035", "reactome": "R-PFA-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10701027" ], "products": [ "species_10701033" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "Q8I616", "PF3D7_1202900", "species_166005" ] }, "reaction_10701162": { "compartment": "compartment_984", "id": "reaction_10701162", "reactome": "R-PFA-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690933" ], "products": [ "species_10701027" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "PF3D7_1202900" ] }, "reaction_10703347": { "compartment": "compartment_70101", "id": "reaction_10703347", "reactome": "R-PFA-9013869", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694974", "species_8982080" ], "products": [ "species_10703345" ], "modifiers": [], "additional_components": [ "PF3D7_0527900", "CHEBI:49537", "CHEBI:47037", "CHEBI:49537", "CHEBI:47037", "A0A5K1K8X8", "PF3D7_0527900" ] }, "reaction_10694983": { "compartment": "compartment_70101", "id": "reaction_10694983", "reactome": "R-PFA-3134962", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3134861", "species_10694979" ], "products": [ "species_10694981" ], "modifiers": [], "additional_components": [ "PF3D7_0310500", "O77360", "PF3D7_0310500" ] }, "reaction_10690562": { "compartment": "compartment_70101", "id": "reaction_10690562", "reactome": "R-PFA-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_202277" ], "products": [ "species_10690560" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "species_202247", "species_179838", "Q8IIE7", "PF3D7_1121900", "species_202247", "species_179838" ] }, "reaction_10693549": { "compartment": "compartment_1222693", "id": "reaction_10693549", "reactome": "R-PFA-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10693546", "catalyst" ] ], "additional_components": [ "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900", "Q8IKJ0", "PF3D7_1464700", "Q8IDF7", "PF3D7_1354400", "C0H4P0", "PF3D7_0721900", "Q8IAQ8", "PF3D7_0806800", "Q8I3R7", "PF3D7_0519200" ] }, "reaction_10688366": { "compartment": "compartment_70101", "id": "reaction_10688366", "reactome": "R-PFA-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_111584", "species_29472" ], "products": [ "species_111294", "species_29404", "species_113578", "species_76577" ], "modifiers": [ [ "species_10688363", "catalyst" ] ], "additional_components": [ "PF3D7_1012600" ] }, "reaction_10689181": { "compartment": "compartment_70101", "id": "reaction_10689181", "reactome": "R-PFA-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29448", "species_29602" ], "products": [ "species_29372", "species_29420", "species_35141" ], "modifiers": [ [ "species_10689178", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_30014", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_113578", "inhibitor" ] ], "additional_components": [ "species_29926", "Q8IDF6", "PF13_0287" ] }, "reaction_10698331": { "compartment": "compartment_7660", "id": "reaction_10698331", "reactome": "R-PFA-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698328", "species_30555" ], "products": [ "species_10698326", "species_113541" ], "modifiers": [ [ "species_10698328", "catalyst" ] ], "additional_components": [ "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10690535": { "compartment": "compartment_70101", "id": "reaction_10690535", "reactome": "R-PFA-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10690512" ], "products": [ "species_29370", "species_10690533" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "Q8IC05", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "P62203", "PF14_0323", "species_74016", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10693927": { "compartment": "compartment_70101", "id": "reaction_10693927", "reactome": "R-PFA-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10690533" ], "products": [ "species_10690537" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10689795": { "compartment": "compartment_70101", "id": "reaction_10689795", "reactome": "R-PFA-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_174390" ], "products": [ "species_111294", "species_29372", "species_71284" ], "modifiers": [ [ "species_10689792", "catalyst" ] ], "additional_components": [ "species_29926", "Q7K6A4", "PF3D7_0922200", "species_74126" ] }, "reaction_10689813": { "compartment": "compartment_70101", "id": "reaction_10689813", "reactome": "R-PFA-175983", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175977", "species_71284" ], "products": [ "species_175978", "species_71285" ], "modifiers": [ [ "species_10689810", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10700735": { "compartment": "compartment_70101", "id": "reaction_10700735", "reactome": "R-PFA-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10700729", "catalyst" ] ], "additional_components": [ "Q8IET4", "PF3D7_1303100", "Q8IM19", "PF3D7_1407500" ] }, "reaction_10698363": { "compartment": "compartment_70101", "id": "reaction_10698363", "reactome": "R-PFA-5692232", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_5692212" ], "products": [ "species_5692216", "species_29364" ], "modifiers": [ [ "species_10697185", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10689805": { "compartment": "compartment_70101", "id": "reaction_10689805", "reactome": "R-PFA-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174393", "species_113592", "species_29424" ], "products": [ "species_29372", "species_29370", "species_29450" ], "modifiers": [ [ "species_10689802", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "species_29926", "Q8I3Y4", "PF3D7_0512200" ] }, "reaction_10689823": { "compartment": "compartment_70101", "id": "reaction_10689823", "reactome": "R-PFA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_176070" ], "products": [ "species_176049" ], "modifiers": [ [ "species_10689820", "catalyst" ] ], "additional_components": [ "CHEBI:29132", "CHEBI:34718", "CHEBI:30614", "CHEBI:8927", "CHEBI:32639", "CHEBI:34479", "Q8ILQ7", "PF14_0187" ] }, "reaction_10687505": { "compartment": "compartment_70101", "id": "reaction_10687505", "reactome": "R-PFA-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29416", "species_76194" ], "products": [ "species_111294", "species_76183", "species_76577" ], "modifiers": [ [ "species_10687502", "catalyst" ] ], "additional_components": [ "PF3D7_0627800" ] }, "reaction_10692132": { "compartment": "compartment_5460", "id": "reaction_10692132", "reactome": "R-PFA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_113539" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10692129", "catalyst" ] ], "additional_components": [ "PF3D7_0627800" ] }, "reaction_10689254": { "compartment": "compartment_7660", "id": "reaction_10689254", "reactome": "R-PFA-111915", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10689245" ], "products": [ "species_113582", "species_10689251" ], "modifiers": [ [ "species_10689245", "catalyst" ] ], "additional_components": [ "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323", "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323", "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10691885": { "compartment": "compartment_70101", "id": "reaction_10691885", "reactome": "R-PFA-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10691877" ], "products": [ "species_113582", "species_10691882" ], "modifiers": [ [ "species_10691877", "catalyst" ] ], "additional_components": [ "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10699811": { "compartment": "compartment_70101", "id": "reaction_10699811", "reactome": "R-PFA-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699781", "species_10699783" ], "products": [ "species_10699789", "species_10699791", "species_10699785", "species_10699803", "species_10699787", "species_10699797", "species_10687798", "species_10699783", "species_10699793", "species_10691650", "species_10699795" ], "modifiers": [ [ "species_10699789", "catalyst" ], [ "species_10699809", "catalyst" ], [ "species_10699803", "catalyst" ], [ "species_10691650", "catalyst" ] ], "additional_components": [ "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IM10", "PF3D7_1408600", "Q8IDR9", "PF3D7_1342000", "Q8IKL9", "PF3D7_1461300", "O97313", "PFC1020c", "Q8I1N8", "PF3D7_0420100", "Q8IAX5", "PF3D7_0813900", "Q8IKE4", "PF3D7_1469300", "O97248", "PF3D7_0306900", "Q8IDB0", "PF3D7_1358800", "Q8I1Q0", "PF3D7_0418700", "O77395", "PF3D7_0316800", "O96224", "PF3D7_0214400", "O77381", "PF3D7_0317600", "C6KT53", "PF3D7_0621500", "Q8IDN4", "PF3D7_1346300", "Q8IAX8", "PF3D7_1346300", "Q8IIR2", "PF3D7_1109400", "Q8IIU8", "PF3D7_1105400", "Q8IEN2", "PF3D7_1308300", "Q8I3R6", "PF3D7_0519400", "Q8IE34", "PF3D7_1327200", "Q8IKH8", "PF3D7_1465900", "Q8IJD4", "PF10_0264", "Q7KQK2", "PF3D7_1402500", "C0H4K8", "PF3D7_0705700", "Q8ILN8", "PF3D7_1421200", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2", "O96258", "PF3D7_0217800", "Q8IK02", "PF3D7_1003500", "Q8IHS5", "PF3D7_1144000", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "C0H5C2", "PF3D7_1317800", "A0A5K1K925", "PF3D7_0516200", "A0A144A2N6", "PF3D7_1230900", "Q8I502", "PF3D7_1242700", "Q8IKV7", "PF3D7_1451900", "Q8IBQ5", "PF3D7_0719700", "Q8IET7", "PF3D7_1302800", "O97249", "PF3D7_0307100", "Q8I3R0", "PF3D7_0520000", "PF3D7_1230900", "PF3D7_0418700", "PF3D7_1469300", "PF3D7_1109400", "C6S3F7", "PF3D7_1136500.2", "Q8IHZ9", "PF3D7_1136500.1", "PF3D7_0214400", "PF3D7_1230900", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "PF3D7_1230900", "PF3D7_0420100", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2", "PF3D7_1451900", "PF3D7_0418700", "PF3D7_0522300", "C6S3F7", "PF3D7_1136500.2", "Q8IHZ9", "PF3D7_1136500.1", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2" ] }, "reaction_10697067": { "compartment": "compartment_17963", "id": "reaction_10697067", "reactome": "R-PFA-5653873", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_964746" ], "modifiers": [ [ "species_10697064", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10694064": { "compartment": "compartment_171062", "id": "reaction_10694064", "reactome": "R-PFA-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10701695": { "compartment": "compartment_70101", "id": "reaction_10701695", "reactome": "R-PFA-8849969", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8849959" ], "products": [ "species_29372", "species_8849958" ], "modifiers": [ [ "species_10701692", "catalyst" ] ], "additional_components": [ "species_179838", "species_202247", "species_179856", "species_1806200", "species_1806224", "species_1806240", "PF3D7_1354200" ] }, "reaction_10694096": { "compartment": "compartment_876", "id": "reaction_10694096", "reactome": "R-PFA-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10693987", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694013": { "compartment": "compartment_876", "id": "reaction_10694013", "reactome": "R-PFA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806240", "species_113592" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10694010", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10688787": { "compartment": "compartment_7660", "id": "reaction_10688787", "reactome": "R-PFA-77584", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688783", "species_10688778" ], "products": [ "species_10688785" ], "modifiers": [], "additional_components": [ "PF3D7_0927600", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I2N3", "PF3D7_0927600" ] }, "reaction_10689594": { "compartment": "compartment_876", "id": "reaction_10689594", "reactome": "R-PFA-165026", "name": "OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164988", "species_74113" ], "products": [ "species_30235", "species_83910" ], "modifiers": [ [ "species_10689591", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10688242": { "compartment": "compartment_70101", "id": "reaction_10688242", "reactome": "R-PFA-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687916", "species_10687864", "species_10687881", "species_72617", "species_10687921" ], "products": [ "species_10687916", "species_10687864", "species_10687881", "species_72617", "species_10687921" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "PF3D7_1206700", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "PF3D7_1206700" ] }, "reaction_10687927": { "compartment": "compartment_70101", "id": "reaction_10687927", "reactome": "R-PFA-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687916", "species_113592" ], "products": [ "species_10687916", "species_29372", "species_29370" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10688234": { "compartment": "compartment_70101", "id": "reaction_10688234", "reactome": "R-PFA-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687864", "species_10688215" ], "products": [ "species_10687864", "species_10688213", "species_10687798" ], "modifiers": [], "additional_components": [ "PF3D7_1143400", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "PF3D7_1143400", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600" ] }, "reaction_10688238": { "compartment": "compartment_70101", "id": "reaction_10688238", "reactome": "R-PFA-72676", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687864", "species_10687798", "species_10687859" ], "products": [ "species_10688236" ], "modifiers": [], "additional_components": [ "PF3D7_1143400", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400" ] }, "reaction_10687937": { "compartment": "compartment_70101", "id": "reaction_10687937", "reactome": "R-PFA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687883", "species_72393" ], "products": [ "species_10687885" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10688240": { "compartment": "compartment_70101", "id": "reaction_10688240", "reactome": "R-PFA-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688236", "species_10687885" ], "products": [ "species_10687887" ], "modifiers": [], "additional_components": [ "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10687935": { "compartment": "compartment_70101", "id": "reaction_10687935", "reactome": "R-PFA-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10687881" ], "products": [ "species_10687883" ], "modifiers": [], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10687929": { "compartment": "compartment_70101", "id": "reaction_10687929", "reactome": "R-PFA-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687903", "species_10687898", "species_10687908" ], "products": [ "species_10687910" ], "modifiers": [], "additional_components": [ "PF3D7_0315100", "Q8IKF0", "PF3D7_1468700", "PF3D7_1107300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100" ] }, "reaction_10688230": { "compartment": "compartment_70101", "id": "reaction_10688230", "reactome": "R-PFA-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688224" ], "products": [ "species_29372", "species_10688228", "species_10688226" ], "modifiers": [], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29438", "C6KSR8", "PF3D7_0607000", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29420", "C6KSR8", "PF3D7_0607000" ] }, "reaction_10688232": { "compartment": "compartment_70101", "id": "reaction_10688232", "reactome": "R-PFA-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688222", "species_10688213", "species_10687923" ], "products": [ "species_10688224" ], "modifiers": [], "additional_components": [ "species_29438", "C6KSR8", "PF3D7_0607000", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29438", "C6KSR8", "PF3D7_0607000" ] }, "reaction_10687968": { "compartment": "compartment_70101", "id": "reaction_10687968", "reactome": "R-PFA-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687964", "species_10687925" ], "products": [ "species_10687966" ], "modifiers": [], "additional_components": [ "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400" ] }, "reaction_10688245": { "compartment": "compartment_70101", "id": "reaction_10688245", "reactome": "R-PFA-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10687966" ], "products": [ "species_10687964", "species_29420", "species_10687883" ], "modifiers": [ [ "species_10687964", "catalyst" ] ], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400" ] }, "reaction_10689620": { "compartment": "compartment_70101", "id": "reaction_10689620", "reactome": "R-PFA-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10687908" ], "products": [ "species_29370", "species_10689618" ], "modifiers": [ [ "species_10689603", "catalyst" ] ], "additional_components": [ "PF3D7_1107300", "PF3D7_1107300", "PF3D7_1246900" ] }, "reaction_10689613": { "compartment": "compartment_70101", "id": "reaction_10689613", "reactome": "R-PFA-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10687760" ], "products": [ "species_29370", "species_10689610" ], "modifiers": [ [ "species_10689603", "catalyst" ] ], "additional_components": [ "PF3D7_1342000", "PF3D7_1342000", "PF3D7_1246900" ] }, "reaction_10702534": { "compartment": "compartment_876", "id": "reaction_10702534", "reactome": "R-PFA-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10693985", "catalyst" ] ], "additional_components": [ "PF3D7_0110600" ] }, "reaction_10702417": { "compartment": "compartment_70101", "id": "reaction_10702417", "reactome": "R-PFA-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702413", "species_10702401" ], "products": [ "species_10702415" ], "modifiers": [], "additional_components": [ "O97322", "PF3D7_1025000", "Q8IJF4", "PF3D7_1025000", "Q8I4X4", "PF3D7_1245800", "Q8II45", "PF3D7_1132000", "Q8IIM8", "PF3D7_1132000", "Q8I2T2", "PF3D7_1132000", "Q8II45", "PF3D7_1132000", "Q8IIM8", "PF3D7_1132000", "Q8I2T2", "PF3D7_1132000", "O97322", "PF3D7_1025000", "Q8IJF4", "PF3D7_1025000", "Q8I4X4", "PF3D7_1245800" ] }, "reaction_10702263": { "compartment": "compartment_70101", "id": "reaction_10702263", "reactome": "R-PFA-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698282", "species_10702261" ], "products": [ "species_10702247" ], "modifiers": [], "additional_components": [ "PF3D7_1313000", "Q8IL63", "PF3D7_1440700", "Q8I5M5", "PF3D7_1440700", "Q8I5M5", "PF3D7_1440700", "Q8IL63", "PF3D7_1440700" ] }, "reaction_10703640": { "compartment": "compartment_70101", "id": "reaction_10703640", "reactome": "R-PFA-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10702203" ], "products": [ "species_10703638" ], "modifiers": [], "additional_components": [ "Q8I3I6", "PF3D7_0528100", "C6KT12", "PF3D7_1246300", "Q8I4W9", "PF3D7_1246300", "Q8I5M5", "PF3D7_1440700", "O96254", "PF3D7_0217300", "Q8I3I6", "PF3D7_0528100", "C6KT12", "PF3D7_1246300", "Q8I4W9", "PF3D7_1246300", "Q8I5M5", "PF3D7_1440700", "O96254", "PF3D7_0217300" ] }, "reaction_10694563": { "compartment": "compartment_5460", "id": "reaction_10694563", "reactome": "R-PFA-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162265", "species_2162212" ], "products": [ "species_2162252", "species_113529", "species_2162198" ], "modifiers": [ [ "species_10694560", "catalyst" ] ], "additional_components": [ "PF3D7_0724300" ] }, "reaction_10694571": { "compartment": "compartment_70616", "id": "reaction_10694571", "reactome": "R-PFA-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10694568", "catalyst" ] ], "additional_components": [ "PF3D7_0607500" ] }, "reaction_10694574": { "compartment": "compartment_5460", "id": "reaction_10694574", "reactome": "R-PFA-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162265", "species_2162209" ], "products": [ "species_2162252", "species_113529", "species_2162215" ], "modifiers": [ [ "species_10694560", "catalyst" ] ], "additional_components": [ "PF3D7_0724300" ] }, "reaction_10694588": { "compartment": "compartment_5460", "id": "reaction_10694588", "reactome": "R-PFA-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162257", "species_2162256" ], "products": [ "species_159450", "species_2162214" ], "modifiers": [ [ "species_10694585", "catalyst" ] ], "additional_components": [ "O96130", "PF3D7_0202700", "species_29926" ] }, "reaction_10688699": { "compartment": "compartment_7660", "id": "reaction_10688699", "reactome": "R-PFA-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688694", "species_30595" ], "products": [ "species_10688696", "species_113541" ], "modifiers": [ [ "species_10687614", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10689161": { "compartment": "compartment_7660", "id": "reaction_10689161", "reactome": "R-PFA-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688696", "species_30595" ], "products": [ "species_113541", "species_10688727" ], "modifiers": [ [ "species_10687614", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10694756": { "compartment": "compartment_70101", "id": "reaction_10694756", "reactome": "R-PFA-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5357707", "species_113592" ], "products": [ "species_111294", "species_29372", "species_5357652" ], "modifiers": [ [ "species_10689792", "catalyst" ] ], "additional_components": [ "species_29926", "Q7K6A4", "PF3D7_0922200", "species_74126" ] }, "reaction_10703615": { "compartment": "compartment_876", "id": "reaction_10703615", "reactome": "R-PFA-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10703611" ], "products": [ "species_10703613" ], "modifiers": [], "additional_components": [ "Q8I1Z1", "PF3D7_0403800", "C0H4R4", "PF3D7_1120400", "Q8IIG3", "PF3D7_1120400", "Q8I1Z1", "PF3D7_0403800", "C0H4R4", "PF3D7_1120400", "Q8IIG3", "PF3D7_1120400" ] }, "reaction_10703582": { "compartment": "compartment_70101", "id": "reaction_10703582", "reactome": "R-PFA-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703578", "species_9653479" ], "products": [ "species_10703580" ], "modifiers": [], "additional_components": [ "Q8I503", "PF3D7_1242600", "Q8IHP6", "PF3D7_1147500", "Q8I503", "PF3D7_1242600", "Q8IHP6", "PF3D7_1147500" ] }, "reaction_10693680": { "compartment": "compartment_70101", "id": "reaction_10693680", "reactome": "R-PFA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1474124" ], "products": [ "species_1475054", "species_1474179" ], "modifiers": [ [ "species_10693677", "catalyst" ] ], "additional_components": [ "species_216785", "C6KTB6", "PF3D7_0628000" ] }, "reaction_10693669": { "compartment": "compartment_70101", "id": "reaction_10693669", "reactome": "R-PFA-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10693666", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "Q8I5H7", "PF3D7_1224000" ] }, "reaction_10693931": { "compartment": "compartment_70101", "id": "reaction_10693931", "reactome": "R-PFA-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690537", "species_1497857" ], "products": [ "species_29870", "species_10693929" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "species_1497857", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10693695": { "compartment": "compartment_70101", "id": "reaction_10693695", "reactome": "R-PFA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693684" ], "products": [ "species_10693677", "species_29370" ], "modifiers": [ [ "species_10693692", "catalyst" ] ], "additional_components": [ "C6KTB6", "PF3D7_0628000", "species_216785", "C6KTB6", "PF3D7_0628000", "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800" ] }, "reaction_10691489": { "compartment": "compartment_70101", "id": "reaction_10691489", "reactome": "R-PFA-426240", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114519" ], "products": [ "species_76108", "species_29370" ], "modifiers": [ [ "species_10691486", "catalyst" ] ], "additional_components": [ "Q8IKC5", "PF3D7_1471400", "Q8I2K9", "PF3D7_1471400" ] }, "reaction_10698647": { "compartment": "compartment_876", "id": "reaction_10698647", "reactome": "R-PFA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694509" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10698644", "catalyst" ] ], "additional_components": [ "PF3D7_0728700" ] }, "reaction_10692642": { "compartment": "compartment_70101", "id": "reaction_10692642", "reactome": "R-PFA-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692638", "species_10692633" ], "products": [ "species_10692640" ], "modifiers": [], "additional_components": [ "PF3D7_0517600", "PF3D7_0528500", "Q8I3I2", "PF3D7_0528500", "Q8I3T2", "PF3D7_0517600" ] }, "reaction_10693489": { "compartment": "compartment_5460", "id": "reaction_10693489", "reactome": "R-PFA-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113581", "species_113525" ], "modifiers": [ [ "species_10693486", "catalyst" ] ], "additional_components": [ "PF3D7_1008900" ] }, "reaction_10693458": { "compartment": "compartment_70101", "id": "reaction_10693458", "reactome": "R-PFA-984689", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693431" ], "products": [ "species_10693433" ], "modifiers": [], "additional_components": [ "Q8I4X5", "PF3D7_1245600", "Q8I5U0", "PF3D7_1245600", "Q8I4X5", "PF3D7_1245600", "Q8I5U0", "PF3D7_1245600" ] }, "reaction_10693456": { "compartment": "compartment_70101", "id": "reaction_10693456", "reactome": "R-PFA-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693410" ], "products": [ "species_10693412" ], "modifiers": [], "additional_components": [ "PF3D7_0317500", "O77382", "PF3D7_0317500" ] }, "reaction_10693480": { "compartment": "compartment_7660", "id": "reaction_10693480", "reactome": "R-PFA-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693476", "species_10693463" ], "products": [ "species_10693478" ], "modifiers": [], "additional_components": [ "Q8IDZ1", "PF3D7_1333700", "C6KSV0", "PF3D7_0617900", "C6KT19", "PF3D7_0617900", "PF3D7_1220900", "Q8I5K4", "PF3D7_1220900", "Q8IDZ1", "PF3D7_1333700", "C6KSV0", "PF3D7_0617900", "C6KT19", "PF3D7_0617900" ] }, "reaction_10703621": { "compartment": "compartment_70101", "id": "reaction_10703621", "reactome": "R-PFA-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703617" ], "products": [ "species_10703619" ], "modifiers": [], "additional_components": [ "PF3D7_0917100", "PF3D7_0917100" ] }, "reaction_10689008": { "compartment": "compartment_7660", "id": "reaction_10689008", "reactome": "R-PFA-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689003" ], "products": [ "species_5635947", "species_10689005" ], "modifiers": [ [ "species_10689003", "catalyst" ] ], "additional_components": [ "A0A143ZYC4", "PF3D7_1129500", "A0A143ZYC4", "PF3D7_1129500", "A0A143ZYC4", "PF3D7_1129500" ] }, "reaction_10689024": { "compartment": "compartment_7660", "id": "reaction_10689024", "reactome": "R-PFA-110250", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689021" ], "products": [ "species_110249", "species_10689014" ], "modifiers": [ [ "species_10689021", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10689031": { "compartment": "compartment_7660", "id": "reaction_10689031", "reactome": "R-PFA-110251", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689028" ], "products": [ "species_29850", "species_10689014" ], "modifiers": [ [ "species_10689028", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10689017": { "compartment": "compartment_7660", "id": "reaction_10689017", "reactome": "R-PFA-110248", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689012" ], "products": [ "species_10689014", "species_30947" ], "modifiers": [ [ "species_10689012", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10688985": { "compartment": "compartment_7660", "id": "reaction_10688985", "reactome": "R-PFA-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688980" ], "products": [ "species_10688982", "species_110242" ], "modifiers": [ [ "species_10688980", "catalyst" ] ], "additional_components": [ "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100" ] }, "reaction_10689062": { "compartment": "compartment_7660", "id": "reaction_10689062", "reactome": "R-PFA-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10689051" ], "products": [ "species_10689059" ], "modifiers": [ [ "species_10689051", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10689109": { "compartment": "compartment_7660", "id": "reaction_10689109", "reactome": "R-PFA-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689067", "species_10689072" ], "products": [ "species_10689074" ], "modifiers": [], "additional_components": [ "PF3D7_1037000", "PF3D7_1023400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10689083": { "compartment": "compartment_7660", "id": "reaction_10689083", "reactome": "R-PFA-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689076" ], "products": [ "species_10689080", "species_113541", "species_10689074" ], "modifiers": [ [ "species_10689076", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10697018": { "compartment": "compartment_7660", "id": "reaction_10697018", "reactome": "R-PFA-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689074", "species_10689059" ], "products": [ "species_10689076" ], "modifiers": [], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10689053": { "compartment": "compartment_7660", "id": "reaction_10689053", "reactome": "R-PFA-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689036", "species_10689049" ], "products": [ "species_10689051" ], "modifiers": [], "additional_components": [ "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697056": { "compartment": "compartment_7660", "id": "reaction_10697056", "reactome": "R-PFA-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697052", "species_10689135" ], "products": [ "species_10697054" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697153": { "compartment": "compartment_7660", "id": "reaction_10697153", "reactome": "R-PFA-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10697144" ], "products": [ "species_10697150", "species_113541" ], "modifiers": [ [ "species_10697144", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697162": { "compartment": "compartment_7660", "id": "reaction_10697162", "reactome": "R-PFA-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697150", "species_30555" ], "products": [ "species_10689036", "species_113541", "species_10697159", "species_10689074" ], "modifiers": [ [ "species_10697150", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "PF3D7_0910500", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10689107": { "compartment": "compartment_7660", "id": "reaction_10689107", "reactome": "R-PFA-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689097" ], "products": [ "species_113541", "species_10689104" ], "modifiers": [ [ "species_10689097", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697094": { "compartment": "compartment_7660", "id": "reaction_10697094", "reactome": "R-PFA-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697090", "species_10697074" ], "products": [ "species_10697092" ], "modifiers": [], "additional_components": [ "Q8ILR6", "PF3D7_1418000", "C6KT34", "PF3D7_0619400", "Q8I426", "PF3D7_0507700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400", "Q8ILR6", "PF3D7_1418000", "C6KT34", "PF3D7_0619400", "Q8I426", "PF3D7_0507700" ] }, "reaction_10697096": { "compartment": "compartment_7660", "id": "reaction_10697096", "reactome": "R-PFA-5654986", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697072", "species_10689104" ], "products": [ "species_10697074" ], "modifiers": [], "additional_components": [ "PF3D7_1338400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400" ] }, "reaction_10689100": { "compartment": "compartment_7660", "id": "reaction_10689100", "reactome": "R-PFA-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29604", "species_10689091" ], "products": [ "species_10689097", "species_113541" ], "modifiers": [ [ "species_10689091", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697125": { "compartment": "compartment_7660", "id": "reaction_10697125", "reactome": "R-PFA-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697116", "species_30555" ], "products": [ "species_113541", "species_10697122" ], "modifiers": [ [ "species_10697116", "catalyst" ] ], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697134": { "compartment": "compartment_7660", "id": "reaction_10697134", "reactome": "R-PFA-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10697122" ], "products": [ "species_10689036", "species_10697131", "species_113541", "species_10689074" ], "modifiers": [ [ "species_10697122", "catalyst" ] ], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500", "PF3D7_0910500", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500" ] }, "reaction_10703478": { "compartment": "compartment_70101", "id": "reaction_10703478", "reactome": "R-PFA-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690526", "species_10703474" ], "products": [ "species_10703476" ], "modifiers": [], "additional_components": [ "species_74016", "P62203", "PF14_0323", "C0H482", "PF3D7_1450000", "Q8IKX5", "PF3D7_1450000", "C0H4K5", "PF3D7_1450000", "C6KSQ1", "PF3D7_1450000", "C0H482", "PF3D7_1450000", "Q8IKX5", "PF3D7_1450000", "C0H4K5", "PF3D7_1450000", "C6KSQ1", "PF3D7_1450000", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10703452": { "compartment": "compartment_70101", "id": "reaction_10703452", "reactome": "R-PFA-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10703445" ], "products": [ "species_29370", "species_10703449" ], "modifiers": [ [ "species_10703445", "catalyst" ] ], "additional_components": [ "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10703397": { "compartment": "compartment_7660", "id": "reaction_10703397", "reactome": "R-PFA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703385" ], "products": [ "species_10703395" ], "modifiers": [], "additional_components": [ "Q8I4W3", "PF3D7_1246900", "Q8I4W3", "PF3D7_1246900" ] }, "reaction_10690163": { "compartment": "compartment_70101", "id": "reaction_10690163", "reactome": "R-PFA-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193707", "species_29364" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690161": { "compartment": "compartment_70101", "id": "reaction_10690161", "reactome": "R-PFA-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690159": { "compartment": "compartment_70101", "id": "reaction_10690159", "reactome": "R-PFA-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_193707", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690157": { "compartment": "compartment_70101", "id": "reaction_10690157", "reactome": "R-PFA-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193724", "species_70106", "species_29364" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10702531": { "compartment": "compartment_70101", "id": "reaction_10702531", "reactome": "R-PFA-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10702528", "catalyst" ] ], "additional_components": [ "Q8II47", "PF3D7_1131800" ] }, "reaction_10690167": { "compartment": "compartment_70101", "id": "reaction_10690167", "reactome": "R-PFA-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_9617026" ], "products": [ "species_193829", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690165": { "compartment": "compartment_70101", "id": "reaction_10690165", "reactome": "R-PFA-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193829", "species_29364" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690171": { "compartment": "compartment_70101", "id": "reaction_10690171", "reactome": "R-PFA-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690169": { "compartment": "compartment_70101", "id": "reaction_10690169", "reactome": "R-PFA-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10702539": { "compartment": "compartment_70101", "id": "reaction_10702539", "reactome": "R-PFA-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_8868393", "species_1806234" ], "modifiers": [ [ "species_10702536", "catalyst" ] ], "additional_components": [ "PF3D7_1131800" ] }, "reaction_10690146": { "compartment": "compartment_70101", "id": "reaction_10690146", "reactome": "R-PFA-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690150": { "compartment": "compartment_70101", "id": "reaction_10690150", "reactome": "R-PFA-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191980", "species_70106", "species_29364" ], "products": [ "species_192030", "species_29366" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690148": { "compartment": "compartment_70101", "id": "reaction_10690148", "reactome": "R-PFA-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690141": { "compartment": "compartment_70101", "id": "reaction_10690141", "reactome": "R-PFA-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_192136", "species_29364" ], "products": [ "species_191980", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690097": { "compartment": "compartment_70101", "id": "reaction_10690097", "reactome": "R-PFA-191322", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191324", "species_191362" ], "products": [ "species_111294", "species_191409" ], "modifiers": [ [ "species_10690091", "catalyst" ] ], "additional_components": [ "Q8II79", "PF3D7_1128400", "species_29926" ] }, "reaction_10690094": { "compartment": "compartment_70101", "id": "reaction_10690094", "reactome": "R-PFA-191303", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191409", "species_191362" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10690091", "catalyst" ] ], "additional_components": [ "Q8II79", "PF3D7_1128400", "species_29926" ] }, "reaction_10696462": { "compartment": "compartment_17957", "id": "reaction_10696462", "reactome": "R-PFA-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10696459", "catalyst" ] ], "additional_components": [ "PF3D7_1011300" ] }, "reaction_10700978": { "compartment": "compartment_17906", "id": "reaction_10700978", "reactome": "R-PFA-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10700973", "catalyst" ] ], "additional_components": [ "Q8I227", "PF3D7_0111900", "Q8IE73", "PF3D7_1324400" ] }, "reaction_10700975": { "compartment": "compartment_17927", "id": "reaction_10700975", "reactome": "R-PFA-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700971", "species_10700962" ], "products": [ "species_10700973" ], "modifiers": [], "additional_components": [ "Q8IE73", "PF3D7_1324400", "PF3D7_0111900", "Q8I227", "PF3D7_0111900", "Q8IE73", "PF3D7_1324400" ] }, "reaction_10703356": { "compartment": "compartment_70101", "id": "reaction_10703356", "reactome": "R-PFA-9020271", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024522" ], "products": [ "species_29356", "species_9024463", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10703366": { "compartment": "compartment_70101", "id": "reaction_10703366", "reactome": "R-PFA-9024993", "name": "EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_9025001" ], "products": [ "species_9025011" ], "modifiers": [ [ "species_10694550", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IM75", "PF3D7_1401300" ] }, "reaction_10703358": { "compartment": "compartment_70101", "id": "reaction_10703358", "reactome": "R-PFA-9020273", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024012" ], "products": [ "species_29356", "species_9024815", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10696999": { "compartment": "compartment_7660", "id": "reaction_10696999", "reactome": "R-PFA-5649856", "name": "Oxidative damage to the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689130" ], "products": [ "species_10696997" ], "modifiers": [], "additional_components": [ "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600" ] }, "reaction_10689156": { "compartment": "compartment_7660", "id": "reaction_10689156", "reactome": "R-PFA-110371", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687076", "species_10689152" ], "products": [ "species_10689154" ], "modifiers": [], "additional_components": [ "PF3D7_1304100", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100" ] }, "reaction_10697012": { "compartment": "compartment_7660", "id": "reaction_10697012", "reactome": "R-PFA-5651805", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689154" ], "products": [ "species_10697009" ], "modifiers": [ [ "species_10689154", "catalyst" ] ], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IES4", "PF3D7_1304100", "O97240", "PF3D7_0305600", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100" ] }, "reaction_10689148": { "compartment": "compartment_7660", "id": "reaction_10689148", "reactome": "R-PFA-110368", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689145" ], "products": [ "species_10689141", "species_113541" ], "modifiers": [ [ "species_10689145", "catalyst" ] ], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c" ] }, "reaction_10698360": { "compartment": "compartment_70101", "id": "reaction_10698360", "reactome": "R-PFA-5691512", "name": "APEH hydrolyses NAc-Ser-protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5691496", "species_29356" ], "products": [ "species_6785226", "species_5691517" ], "modifiers": [ [ "species_10698357", "catalyst" ] ], "additional_components": [ "species_5691517", "species_6785226", "PF3D7_0321500" ] }, "reaction_10700732": { "compartment": "compartment_70101", "id": "reaction_10700732", "reactome": "R-PFA-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10700710" ], "products": [ "species_10700717", "species_71285" ], "modifiers": [ [ "species_10700729", "catalyst" ] ], "additional_components": [ "Q8IIC9", "PF3D7_1123400", "species_29438", "O96203", "PF3D7_0212300", "Q8IIC9", "PF3D7_1123400", "species_29438", "O96203", "PF3D7_0212300", "Q8IET4", "PF3D7_1303100", "Q8IM19", "PF3D7_1407500" ] }, "reaction_10703116": { "compartment": "compartment_13231", "id": "reaction_10703116", "reactome": "R-PFA-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703109" ], "products": [ "species_10703107" ], "modifiers": [], "additional_components": [ "PF3D7_0416500", "PF3D7_0416500" ] }, "reaction_10694753": { "compartment": "compartment_70101", "id": "reaction_10694753", "reactome": "R-PFA-2395872", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395868" ], "products": [ "species_111294", "species_2395878" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10694751": { "compartment": "compartment_70101", "id": "reaction_10694751", "reactome": "R-PFA-2395849", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10694748": { "compartment": "compartment_70101", "id": "reaction_10694748", "reactome": "R-PFA-2395818", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395822" ], "products": [ "species_111294", "species_2395855" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10698420": { "compartment": "compartment_5460", "id": "reaction_10698420", "reactome": "R-PFA-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10698407" ], "products": [ "species_113529", "species_29362", "species_10698401" ], "modifiers": [ [ "species_10698417", "catalyst" ] ], "additional_components": [ "Q8II35", "PF3D7_1132900", "CHEBI:50746", "PF3D7_1132900", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10698415": { "compartment": "compartment_5460", "id": "reaction_10698415", "reactome": "R-PFA-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10698405" ], "products": [ "species_5693978", "species_5693984", "species_10698407" ], "modifiers": [ [ "species_10698412", "catalyst" ] ], "additional_components": [ "Q8II35", "PF3D7_1132900", "CHEBI:14949", "Q8II35", "PF3D7_1132900", "CHEBI:50746", "PF3D7_1365500" ] }, "reaction_10697634": { "compartment": "compartment_70101", "id": "reaction_10697634", "reactome": "R-PFA-5688797", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10689705" ], "products": [ "species_10689705", "species_10689703" ], "modifiers": [ [ "species_10697631", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F0", "PF3D7_1226800", "Q8IIP4", "PF3D7_1111900" ] }, "reaction_10697618": { "compartment": "compartment_7660", "id": "reaction_10697618", "reactome": "R-PFA-5688786", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697614", "species_10697609" ], "products": [ "species_10697616" ], "modifiers": [], "additional_components": [ "PF3D7_1226800", "Q8IJS8", "PF3D7_1011700", "Q8IJS8", "PF3D7_1011700", "Q8I5F0", "PF3D7_1226800" ] }, "reaction_10698080": { "compartment": "compartment_70101", "id": "reaction_10698080", "reactome": "R-PFA-5689111", "name": "PARK2 autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698072", "species_10693227" ], "products": [ "species_10697641" ], "modifiers": [ [ "species_10693227", "catalyst" ] ], "additional_components": [ "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_0303800", "PF3D7_0303800", "PF3D7_0303800" ] }, "reaction_10697638": { "compartment": "compartment_7660", "id": "reaction_10697638", "reactome": "R-PFA-5688834", "name": "ATXN3 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697614", "species_10697078" ], "products": [ "species_10697636" ], "modifiers": [], "additional_components": [ "PF3D7_1226800", "C6KT34", "PF3D7_0619400", "C6KT34", "PF3D7_0619400", "Q8I5F0", "PF3D7_1226800" ] }, "reaction_10698075": { "compartment": "compartment_70101", "id": "reaction_10698075", "reactome": "R-PFA-5688837", "name": "ATXN3 deubiquitinates polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10697643" ], "products": [ "species_10697645", "species_10698072" ], "modifiers": [ [ "species_10697643", "catalyst" ] ], "additional_components": [ "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800" ] }, "reaction_10698077": { "compartment": "compartment_70101", "id": "reaction_10698077", "reactome": "R-PFA-5689085", "name": "ATXN3 binds polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697641", "species_10697620" ], "products": [ "species_10697643" ], "modifiers": [], "additional_components": [ "PF3D7_0303800", "PF3D7_1226800", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800" ] }, "reaction_10703328": { "compartment": "compartment_70101", "id": "reaction_10703328", "reactome": "R-PFA-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10696164", "catalyst" ] ], "additional_components": [ "PF3D7_1432100" ] }, "reaction_10699253": { "compartment": "compartment_70101", "id": "reaction_10699253", "reactome": "R-PFA-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29708", "species_29450" ], "modifiers": [ [ "species_10699250", "catalyst" ] ], "additional_components": [ "species_216785", "C0H490", "PF3D7_0406400" ] }, "reaction_10698430": { "compartment": "compartment_70101", "id": "reaction_10698430", "reactome": "R-PFA-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694074", "species_29450" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10698427", "catalyst" ] ], "additional_components": [ "species_216785", "Q8IIM5", "PF3D7_1113700" ] }, "reaction_10696882": { "compartment": "compartment_70101", "id": "reaction_10696882", "reactome": "R-PFA-5618328", "name": "ATAT acetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691147", "species_76183" ], "products": [ "species_10696874", "species_76194" ], "modifiers": [ [ "species_10696879", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29420", "species_29438", "PFI1220w" ] }, "reaction_10696885": { "compartment": "compartment_70101", "id": "reaction_10696885", "reactome": "R-PFA-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696874", "species_76194" ], "products": [ "species_10691147", "species_76183" ], "modifiers": [ [ "species_10696504", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29420", "species_29438", "PF3D7_1008000" ] }, "reaction_10697600": { "compartment": "compartment_17927", "id": "reaction_10697600", "reactome": "R-PFA-5688294", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688282", "species_10697590" ], "products": [ "species_5688281", "species_10689386", "species_5688340" ], "modifiers": [ [ "species_10697597", "catalyst" ] ], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "species_216785", "Q8IE47", "PF13_0152" ] }, "reaction_10689159": { "compartment": "compartment_70101", "id": "reaction_10689159", "reactome": "R-PFA-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10688285", "catalyst" ], [ "species_29372", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IE40", "PF3D7_1327800", "Q8IE67", "PF3D7_1327800" ] }, "reaction_10688292": { "compartment": "compartment_70101", "id": "reaction_10688292", "reactome": "R-PFA-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_113592" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10688289", "catalyst" ] ], "additional_components": [ "Q8IE40", "PF3D7_1327800", "Q8IE67", "PF3D7_1327800" ] }, "reaction_10689586": { "compartment": "compartment_7660", "id": "reaction_10689586", "reactome": "R-PFA-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10688553" ], "modifiers": [], "additional_components": [ "PF3D7_1444300" ] }, "reaction_10693747": { "compartment": "compartment_12045", "id": "reaction_10693747", "reactome": "R-PFA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500596" ], "products": [ "species_1498728", "species_1524021" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693744": { "compartment": "compartment_12045", "id": "reaction_10693744", "reactome": "R-PFA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500594" ], "products": [ "species_1524021", "species_1500596" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693735": { "compartment": "compartment_12045", "id": "reaction_10693735", "reactome": "R-PFA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_1500596" ], "products": [ "species_76116", "species_1500594" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693737": { "compartment": "compartment_12045", "id": "reaction_10693737", "reactome": "R-PFA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728" ], "products": [ "species_76116", "species_1500596" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693759": { "compartment": "compartment_12045", "id": "reaction_10693759", "reactome": "R-PFA-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10688689", "catalyst" ] ], "additional_components": [ "O97295", "PF3D7_0322300" ] }, "reaction_10703201": { "compartment": "compartment_70101", "id": "reaction_10703201", "reactome": "R-PFA-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10703198", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10691072": { "compartment": "compartment_70101", "id": "reaction_10691072", "reactome": "R-PFA-379387", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10691067", "catalyst" ], [ "species_10691070", "inhibitor" ] ], "additional_components": [ "PF3D7_1468300", "Q8IKF4", "PF3D7_1468300" ] }, "reaction_10703636": { "compartment": "compartment_876", "id": "reaction_10703636", "reactome": "R-PFA-9679775", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691067", "species_9679778" ], "products": [ "species_10691070" ], "modifiers": [], "additional_components": [ "PF3D7_1468300", "Q8IKF4", "PF3D7_1468300" ] }, "reaction_10701636": { "compartment": "compartment_20699", "id": "reaction_10701636", "reactome": "R-PFA-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701627" ], "products": [ "species_10701633" ], "modifiers": [ [ "species_10701627", "catalyst" ] ], "additional_components": [ "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420", "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900" ] }, "reaction_10701609": { "compartment": "compartment_20699", "id": "reaction_10701609", "reactome": "R-PFA-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10701605" ], "products": [ "species_10701607" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "Q8IE08", "PF3D7_1332000", "C0H5D3", "PF3D7_1324700", "Q8IKE6", "PF3D7_1469100", "Q8IE08", "PF3D7_1332000", "C0H5D3", "PF3D7_1324700", "Q8IKE6", "PF3D7_1469100", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701629": { "compartment": "compartment_20699", "id": "reaction_10701629", "reactome": "R-PFA-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701617", "species_10694050" ], "products": [ "species_10701627" ], "modifiers": [], "additional_components": [ "Q8IL42", "PF3D7_1442900", "species_29438", "Q7KQL3", "PF10_0203", "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900" ] }, "reaction_10703441": { "compartment": "compartment_70101", "id": "reaction_10703441", "reactome": "R-PFA-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703437", "species_10703409" ], "products": [ "species_10703439" ], "modifiers": [], "additional_components": [ "Q8I599", "PF3D7_1232300", "O96183", "PF3D7_0210000", "Q8I655", "PF3D7_0219400.1", "Q8IL71", "PF3D7_1439800", "Q8IE08", "PF3D7_1332000", "C0H4S2", "PF3D7_0806300", "C0H4W6", "PF3D7_0821800", "O77346", "PF3D7_0312200", "O77346", "PF3D7_0312200", "Q8I599", "PF3D7_1232300", "O96183", "PF3D7_0210000", "Q8I655", "PF3D7_0219400.1", "Q8IL71", "PF3D7_1439800", "Q8IE08", "PF3D7_1332000", "C0H4S2", "PF3D7_0806300", "C0H4W6", "PF3D7_0821800" ] }, "reaction_10694386": { "compartment": "compartment_70616", "id": "reaction_10694386", "reactome": "R-PFA-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694380", "species_10694378", "species_10694353" ], "products": [ "species_10694384" ], "modifiers": [], "additional_components": [ "PF3D7_1368600", "Q8IJ34", "PF3D7_1037300", "Q8ID24", "PF3D7_1368600", "Q8I5W2", "PF3D7_1208600", "PF3D7_0627400", "C6KTB0", "PF3D7_0627400", "Q8IJ34", "PF3D7_1037300", "Q8ID24", "PF3D7_1368600", "Q8I5W2", "PF3D7_1208600" ] }, "reaction_10687270": { "compartment": "compartment_70101", "id": "reaction_10687270", "reactome": "R-PFA-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29448", "species_29472" ], "products": [ "species_111294", "species_29404", "species_29642", "species_76577" ], "modifiers": [ [ "species_10687267", "catalyst" ] ], "additional_components": [ "O77330", "PF3D7_0309500" ] }, "reaction_10687260": { "compartment": "compartment_5460", "id": "reaction_10687260", "reactome": "R-PFA-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113587", "species_113552" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10703196": { "compartment": "compartment_5460", "id": "reaction_10703196", "reactome": "R-PFA-8954468", "name": "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113553" ], "products": [ "species_29374", "species_8954466", "species_113529" ], "modifiers": [ [ "species_10703193", "catalyst" ] ], "additional_components": [ "PF3D7_1437000" ] }, "reaction_10691653": { "compartment": "compartment_70101", "id": "reaction_10691653", "reactome": "R-PFA-429714", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10691634" ], "products": [ "species_29370", "species_10691638" ], "modifiers": [ [ "species_10691650", "catalyst" ] ], "additional_components": [ "PF3D7_0915800", "PF3D7_0915800", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2" ] }, "reaction_10691668": { "compartment": "compartment_20699", "id": "reaction_10691668", "reactome": "R-PFA-429798", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_428270" ], "products": [ "species_429773", "species_429789" ], "modifiers": [ [ "species_10691665", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10691663": { "compartment": "compartment_876", "id": "reaction_10691663", "reactome": "R-PFA-429786", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_429807" ], "products": [ "species_429776", "species_112275" ], "modifiers": [ [ "species_10691660", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10691582": { "compartment": "compartment_70101", "id": "reaction_10691582", "reactome": "R-PFA-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_428163" ], "products": [ "species_428126", "species_76194" ], "modifiers": [ [ "species_10691579", "catalyst" ] ], "additional_components": [ "Q8IM57", "PF3D7_1403700" ] }, "reaction_10703662": { "compartment": "compartment_70101", "id": "reaction_10703662", "reactome": "R-PFA-9695890", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_419305" ], "modifiers": [ [ "species_10703659", "catalyst" ] ], "additional_components": [ "C6KSY4", "PF3D7_0916000", "Q8I2Z2", "PF3D7_0916000" ] }, "reaction_10703229": { "compartment": "compartment_12045", "id": "reaction_10703229", "reactome": "R-PFA-8959462", "name": "SAMD8 transforms PE and CERA to CPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8959490", "species_8959486" ], "products": [ "species_8959463" ], "modifiers": [ [ "species_10703226", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10692484": { "compartment": "compartment_70101", "id": "reaction_10692484", "reactome": "R-PFA-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10692481", "catalyst" ] ], "additional_components": [ "PF3D7_0801800" ] }, "reaction_10692090": { "compartment": "compartment_70101", "id": "reaction_10692090", "reactome": "R-PFA-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10692087", "catalyst" ] ], "additional_components": [ "Q8IJM5", "PF3D7_1017400" ] }, "reaction_10692499": { "compartment": "compartment_70101", "id": "reaction_10692499", "reactome": "R-PFA-548814", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29508", "species_200993" ], "products": [ "species_113528", "species_548812", "species_76194" ], "modifiers": [ [ "species_10692496", "catalyst" ] ], "additional_components": [ "Q8I251", "PF3D7_0109300" ] }, "reaction_10690466": { "compartment": "compartment_70101", "id": "reaction_10690466", "reactome": "R-PFA-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_111294", "species_29356", "species_200993", "species_76577" ], "modifiers": [ [ "species_10690463", "catalyst" ] ], "additional_components": [ "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10692511": { "compartment": "compartment_70101", "id": "reaction_10692511", "reactome": "R-PFA-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_428139", "species_29366" ], "modifiers": [ [ "species_10692508", "catalyst" ] ], "additional_components": [ "Q8II05", "PF3D7_1135900" ] }, "reaction_10697326": { "compartment": "compartment_12045", "id": "reaction_10697326", "reactome": "R-PFA-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_29356", "species_5676634" ], "modifiers": [ [ "species_10697323", "catalyst" ] ], "additional_components": [ "C0H5F1", "PF3D7_1331600" ] }, "reaction_10692492": { "compartment": "compartment_70101", "id": "reaction_10692492", "reactome": "R-PFA-548800", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_29508" ], "products": [ "species_113528", "species_548816", "species_76194" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10698277": { "compartment": "compartment_12045", "id": "reaction_10698277", "reactome": "R-PFA-5690565", "name": "SCD desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10698274", "catalyst" ] ], "additional_components": [ "Q8I0W9", "PF3D7_0511200" ] }, "reaction_10701599": { "compartment": "compartment_12045", "id": "reaction_10701599", "reactome": "R-PFA-8847579", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10701596", "catalyst" ] ], "additional_components": [ "Q8I0W9", "PF3D7_0511200" ] }, "reaction_10698099": { "compartment": "compartment_5460", "id": "reaction_10698099", "reactome": "R-PFA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690540", "species_113521" ], "products": [ "species_29374", "species_5690519" ], "modifiers": [ [ "species_10698096", "catalyst" ] ], "additional_components": [ "species_164991", "CHEBI:61907", "species_174602", "CHEBI:59554", "PF3D7_0217900" ] }, "reaction_10701663": { "compartment": "compartment_70101", "id": "reaction_10701663", "reactome": "R-PFA-8848250", "name": "ACBD6 binds LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164991", "species_10701659" ], "products": [ "species_10701661" ], "modifiers": [], "additional_components": [ "Q8IBL1", "PF3D7_1119000", "Q8IIH7", "PF3D7_1119000", "Q8IBL1", "PF3D7_1119000", "Q8IIH7", "PF3D7_1119000", "species_164991" ] }, "reaction_10694426": { "compartment": "compartment_17957", "id": "reaction_10694426", "reactome": "R-PFA-2046088", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046052", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046051", "species_162743", "species_159751" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10694424": { "compartment": "compartment_12045", "id": "reaction_10694424", "reactome": "R-PFA-2046085", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_2046056", "species_162743" ], "products": [ "species_2046064", "species_2046049", "species_2046062" ], "modifiers": [ [ "species_10694421", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10694430": { "compartment": "compartment_12045", "id": "reaction_10694430", "reactome": "R-PFA-2046098", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_162743", "species_2046044" ], "products": [ "species_2046064", "species_2046049", "species_2046063" ], "modifiers": [ [ "species_10694421", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10694428": { "compartment": "compartment_17957", "id": "reaction_10694428", "reactome": "R-PFA-2046094", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046042", "species_113601" ], "products": [ "species_113519", "species_113564", "species_162743", "species_159751", "species_2046045" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10694555": { "compartment": "compartment_70101", "id": "reaction_10694555", "reactome": "R-PFA-2161999", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142811", "species_29450" ], "products": [ "species_29356", "species_2142678", "species_111745" ], "modifiers": [ [ "species_10694540", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10694543": { "compartment": "compartment_70101", "id": "reaction_10694543", "reactome": "R-PFA-2161959", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_2142790" ], "products": [ "species_29356", "species_2142716", "species_111745" ], "modifiers": [ [ "species_10694540", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10694529": { "compartment": "compartment_70101", "id": "reaction_10694529", "reactome": "R-PFA-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10694534": { "compartment": "compartment_70101", "id": "reaction_10694534", "reactome": "R-PFA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_879629" ], "modifiers": [ [ "species_10694531", "catalyst" ] ], "additional_components": [ "Q8ILQ7", "PF14_0187", "species_29450" ] }, "reaction_10694526": { "compartment": "compartment_70101", "id": "reaction_10694526", "reactome": "R-PFA-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_265283", "species_29364" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690909": { "compartment": "compartment_70101", "id": "reaction_10690909", "reactome": "R-PFA-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10690906", "catalyst" ] ], "additional_components": [ "C0H473", "PF3D7_1453700", "Q8IKU1", "PF3D7_1453700", "A0A144A1J3", "PF3D7_1453700" ] }, "reaction_10693717": { "compartment": "compartment_12045", "id": "reaction_10693717", "reactome": "R-PFA-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10693708", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693711": { "compartment": "compartment_12045", "id": "reaction_10693711", "reactome": "R-PFA-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498740" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10693708", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693714": { "compartment": "compartment_12045", "id": "reaction_10693714", "reactome": "R-PFA-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10693703", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693755": { "compartment": "compartment_12045", "id": "reaction_10693755", "reactome": "R-PFA-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10693752", "catalyst" ] ], "additional_components": [ "PF3D7_1358000" ] }, "reaction_10693706": { "compartment": "compartment_12045", "id": "reaction_10693706", "reactome": "R-PFA-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_975614" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10693703", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693739": { "compartment": "compartment_12045", "id": "reaction_10693739", "reactome": "R-PFA-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498738" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693723": { "compartment": "compartment_12045", "id": "reaction_10693723", "reactome": "R-PFA-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693757": { "compartment": "compartment_12045", "id": "reaction_10693757", "reactome": "R-PFA-1482887", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10693752", "catalyst" ] ], "additional_components": [ "PF3D7_1358000" ] }, "reaction_10693720": { "compartment": "compartment_12045", "id": "reaction_10693720", "reactome": "R-PFA-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498724" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693741": { "compartment": "compartment_12045", "id": "reaction_10693741", "reactome": "R-PFA-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498722" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693923": { "compartment": "compartment_70101", "id": "reaction_10693923", "reactome": "R-PFA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10693920", "catalyst" ] ], "additional_components": [ "Q8IIB7", "PF3D7_1124600", "Q8IM71", "PF3D7_1401800" ] }, "reaction_10693778": { "compartment": "compartment_12045", "id": "reaction_10693778", "reactome": "R-PFA-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_1500581", "species_109395" ], "modifiers": [ [ "species_10693775", "catalyst" ] ], "additional_components": [ "C6KTB9", "PF3D7_0628300.1", "species_29926", "species_1981162" ] }, "reaction_10693889": { "compartment": "compartment_12045", "id": "reaction_10693889", "reactome": "R-PFA-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428686", "species_110614" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10693886", "catalyst" ] ], "additional_components": [ "Q8IDM2", "PF3D7_1347700" ] }, "reaction_10693900": { "compartment": "compartment_12045", "id": "reaction_10693900", "reactome": "R-PFA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10693897", "catalyst" ] ], "additional_components": [ "species_29926", "O77317", "PF3D7_0303200" ] }, "reaction_10693906": { "compartment": "compartment_20699", "id": "reaction_10693906", "reactome": "R-PFA-1483211", "name": "PC:PITPNB is transported from the Golgi membrane to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693849" ], "products": [ "species_10693904" ], "modifiers": [], "additional_components": [ "Q8IDI9", "PF3D7_1351000", "species_194276", "species_194276", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693910": { "compartment": "compartment_12045", "id": "reaction_10693910", "reactome": "R-PFA-1483219", "name": "PC is exchanged with PI by PITPNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_10693904" ], "products": [ "species_426925", "species_10693908" ], "modifiers": [], "additional_components": [ "species_194276", "Q8IDI9", "PF3D7_1351000", "species_1806199", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693925": { "compartment": "compartment_12045", "id": "reaction_10693925", "reactome": "R-PFA-1483229", "name": "PI:PITPNB is transported from the ER membrane to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693908" ], "products": [ "species_10693847" ], "modifiers": [], "additional_components": [ "species_1806199", "Q8IDI9", "PF3D7_1351000", "species_1806199", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10703182": { "compartment": "compartment_984", "id": "reaction_10703182", "reactome": "R-PFA-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2173763" ], "products": [ "species_8954142", "species_8952253" ], "modifiers": [ [ "species_10703179", "catalyst" ] ], "additional_components": [ "PF3D7_0629300" ] }, "reaction_10693795": { "compartment": "compartment_12045", "id": "reaction_10693795", "reactome": "R-PFA-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_426639", "species_109395" ], "modifiers": [ [ "species_10693792", "catalyst" ] ], "additional_components": [ "species_29926", "species_1981162", "C0H5B7", "PF3D7_1315600" ] }, "reaction_10702550": { "compartment": "compartment_70101", "id": "reaction_10702550", "reactome": "R-PFA-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_1602448" ], "products": [ "species_426755", "species_426658" ], "modifiers": [ [ "species_10702547", "catalyst" ] ], "additional_components": [ "Q8IAY0", "PF3D7_0814400", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693869": { "compartment": "compartment_12045", "id": "reaction_10693869", "reactome": "R-PFA-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_111294", "species_426955" ], "modifiers": [ [ "species_10693866", "catalyst" ] ], "additional_components": [ "species_29926", "Q8ILZ6", "PF3D7_1409900" ] }, "reaction_10693859": { "compartment": "compartment_12045", "id": "reaction_10693859", "reactome": "R-PFA-1483089", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_1500581" ], "products": [ "species_1498751", "species_1500646" ], "modifiers": [ [ "species_10693856", "catalyst" ] ], "additional_components": [ "PF3D7_1366800" ] }, "reaction_10693879": { "compartment": "compartment_12045", "id": "reaction_10693879", "reactome": "R-PFA-1483186", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_200736" ], "products": [ "species_264618", "species_1500646" ], "modifiers": [ [ "species_10693876", "catalyst" ] ], "additional_components": [ "PF3D7_1366800" ] }, "reaction_10693824": { "compartment": "compartment_70101", "id": "reaction_10693824", "reactome": "R-PFA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_113592" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10693821", "catalyst" ] ], "additional_components": [ "Q8IIB7", "PF3D7_1124600", "Q8IM71", "PF3D7_1401800" ] }, "reaction_10693840": { "compartment": "compartment_12045", "id": "reaction_10693840", "reactome": "R-PFA-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10693837", "catalyst" ] ], "additional_components": [ "Q8IEE9", "PF3D7_1316600" ] }, "reaction_10693769": { "compartment": "compartment_12045", "id": "reaction_10693769", "reactome": "R-PFA-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_426925", "species_109395" ], "modifiers": [ [ "species_10693766", "catalyst" ] ], "additional_components": [ "C6KTB9", "PF3D7_0628300.1", "species_29926", "species_1981162" ] }, "reaction_10693785": { "compartment": "compartment_20699", "id": "reaction_10693785", "reactome": "R-PFA-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_429785", "species_109395" ], "modifiers": [ [ "species_10693782", "catalyst" ] ], "additional_components": [ "species_29926", "species_1981162", "C6KTB9", "PF3D7_0628300.1" ] }, "reaction_10702281": { "compartment": "compartment_984", "id": "reaction_10702281", "reactome": "R-PFA-8865637", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8865642", "species_74113" ], "products": [ "species_8865629", "species_83910" ], "modifiers": [ [ "species_10702278", "catalyst" ] ], "additional_components": [ "PF3D7_0529200" ] }, "reaction_10693874": { "compartment": "compartment_70616", "id": "reaction_10693874", "reactome": "R-PFA-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524101", "species_110577" ], "products": [ "species_159450", "species_1524064" ], "modifiers": [ [ "species_10693871", "catalyst" ] ], "additional_components": [ "PF3D7_1409900" ] }, "reaction_10694115": { "compartment": "compartment_876", "id": "reaction_10694115", "reactome": "R-PFA-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_1806224", "species_29370" ], "modifiers": [ [ "species_10694015", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694018": { "compartment": "compartment_876", "id": "reaction_10694018", "reactome": "R-PFA-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_1806240", "species_29370" ], "modifiers": [ [ "species_10694015", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694081": { "compartment": "compartment_876", "id": "reaction_10694081", "reactome": "R-PFA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10694078", "catalyst" ] ], "additional_components": [ "A0A143ZZC6", "PF3D7_1111600", "Q8IC15", "PF3D7_0705500" ] }, "reaction_10693990": { "compartment": "compartment_876", "id": "reaction_10693990", "reactome": "R-PFA-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10693987", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694086": { "compartment": "compartment_876", "id": "reaction_10694086", "reactome": "R-PFA-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10694040", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694091": { "compartment": "compartment_876", "id": "reaction_10694091", "reactome": "R-PFA-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10694088", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694120": { "compartment": "compartment_876", "id": "reaction_10694120", "reactome": "R-PFA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10694117", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694129": { "compartment": "compartment_876", "id": "reaction_10694129", "reactome": "R-PFA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10694126", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694132": { "compartment": "compartment_876", "id": "reaction_10694132", "reactome": "R-PFA-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10694088", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694043": { "compartment": "compartment_876", "id": "reaction_10694043", "reactome": "R-PFA-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10694040", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10702655": { "compartment": "compartment_20699", "id": "reaction_10702655", "reactome": "R-PFA-8870499", "name": "PLEKHA3,8 bind PI4P, ARF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690955", "species_10702651", "species_1806217" ], "products": [ "species_10702653" ], "modifiers": [], "additional_components": [ "PF10_0203", "Q8I2Z4", "PF3D7_0915800", "species_392417", "Q8I2Z4", "PF3D7_0915800", "Q7KQL3", "PF10_0203" ] }, "reaction_10694109": { "compartment": "compartment_12045", "id": "reaction_10694109", "reactome": "R-PFA-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806234" ], "products": [ "species_29372", "species_426639" ], "modifiers": [ [ "species_10694106", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694083": { "compartment": "compartment_20699", "id": "reaction_10694083", "reactome": "R-PFA-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10694112": { "compartment": "compartment_20699", "id": "reaction_10694112", "reactome": "R-PFA-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_29372", "species_1524146" ], "modifiers": [ [ "species_10694101", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694055": { "compartment": "compartment_20699", "id": "reaction_10694055", "reactome": "R-PFA-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10694052", "catalyst" ] ], "additional_components": [ "species_29438", "Q7KQL3", "PF10_0203", "Q8I406", "PF3D7_0509800" ] }, "reaction_10694023": { "compartment": "compartment_20699", "id": "reaction_10694023", "reactome": "R-PFA-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10694020", "catalyst" ] ], "additional_components": [ "PF3D7_0705500" ] }, "reaction_10694104": { "compartment": "compartment_20699", "id": "reaction_10694104", "reactome": "R-PFA-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806159" ], "products": [ "species_29372", "species_1524146" ], "modifiers": [ [ "species_10694101", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694124": { "compartment": "compartment_20699", "id": "reaction_10694124", "reactome": "R-PFA-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694122", "species_10694050" ], "products": [ "species_10694052" ], "modifiers": [], "additional_components": [ "PF3D7_0509800", "species_29438", "Q7KQL3", "PF10_0203", "species_29438", "Q7KQL3", "PF10_0203", "Q8I406", "PF3D7_0509800" ] }, "reaction_10694093": { "compartment": "compartment_172574", "id": "reaction_10694093", "reactome": "R-PFA-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_1806198", "species_29370" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10688692": { "compartment": "compartment_70101", "id": "reaction_10688692", "reactome": "R-PFA-75900", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_76103" ], "products": [ "species_549167", "species_76194" ], "modifiers": [ [ "species_10688689", "catalyst" ] ], "additional_components": [ "O97295", "PF3D7_0322300" ] }, "reaction_10688586": { "compartment": "compartment_70101", "id": "reaction_10688586", "reactome": "R-PFA-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76116" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10688583", "catalyst" ] ], "additional_components": [ "Q8IDI4", "PF3D7_1351600" ] }, "reaction_10688682": { "compartment": "compartment_70101", "id": "reaction_10688682", "reactome": "R-PFA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76108", "species_29356" ], "products": [ "species_29372", "species_76103" ], "modifiers": [ [ "species_10688679", "catalyst" ] ], "additional_components": [ "O77317", "PF3D7_0303200" ] }, "reaction_10688368": { "compartment": "compartment_5460", "id": "reaction_10688368", "reactome": "R-PFA-73916", "name": "2 acetyl-CoA <=> acetoacetyl-CoA + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559" ], "products": [ "species_29374", "species_73871" ], "modifiers": [ [ "species_10687343", "catalyst" ] ], "additional_components": [ "Q8IKW7", "PF3D7_1450900" ] }, "reaction_10696583": { "compartment": "compartment_876", "id": "reaction_10696583", "reactome": "R-PFA-5340320", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5340315" ], "products": [ "species_5340299" ], "modifiers": [ [ "species_10696580", "catalyst" ] ], "additional_components": [ "PF3D7_0915800" ] }, "reaction_10693976": { "compartment": "compartment_876", "id": "reaction_10693976", "reactome": "R-PFA-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10693973", "catalyst" ] ], "additional_components": [ "Q8I537", "PF3D7_1238600", "species_29926" ] }, "reaction_10702983": { "compartment": "compartment_7660", "id": "reaction_10702983", "reactome": "R-PFA-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702972", "species_77087" ], "products": [ "species_77502", "species_10702975" ], "modifiers": [ [ "species_10702980", "catalyst" ] ], "additional_components": [ "PF3D7_0818900", "PF3D7_0818900", "PF3D7_1142700" ] }, "reaction_10703019": { "compartment": "compartment_70101", "id": "reaction_10703019", "reactome": "R-PFA-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10689442" ], "products": [ "species_71285", "species_10703011" ], "modifiers": [ [ "species_10703016", "catalyst" ] ], "additional_components": [ "PF3D7_1357000", "PF3D7_1357000", "PF3D7_0916600" ] }, "reaction_10703002": { "compartment": "compartment_70101", "id": "reaction_10703002", "reactome": "R-PFA-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696509", "species_71284" ], "products": [ "species_10702997", "species_71285" ], "modifiers": [ [ "species_10702999", "catalyst" ] ], "additional_components": [ "PF3D7_0619400", "PF3D7_0619400", "PF3D7_1142700" ] }, "reaction_10695844": { "compartment": "compartment_7660", "id": "reaction_10695844", "reactome": "R-PFA-4568914", "name": "SUMOylation of BLM with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695835", "species_10695825" ], "products": [ "species_10695841", "species_10694930" ], "modifiers": [ [ "species_10695835", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_0918600", "PF3D7_0918600", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695934": { "compartment": "compartment_7660", "id": "reaction_10695934", "reactome": "R-PFA-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695924" ], "products": [ "species_10695932", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1432600", "Q8ILD6", "PF3D7_1432600", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695805": { "compartment": "compartment_7660", "id": "reaction_10695805", "reactome": "R-PFA-4551724", "name": "PIAS4 SUMOylates HERC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695789", "species_10694938" ], "products": [ "species_10695802", "species_10694930" ], "modifiers": [ [ "species_10695666", "catalyst" ] ], "additional_components": [ "Q8IDD6", "PF3D7_1356600", "Q8I5L0", "PF3D7_1356600", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I444", "PF3D7_0505800", "Q8I5L0", "PF3D7_1356600", "Q8IDD6", "PF3D7_1356600", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695984": { "compartment": "compartment_7660", "id": "reaction_10695984", "reactome": "R-PFA-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695974" ], "products": [ "species_10695982", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0925700", "Q8I444", "PF3D7_0505800", "Q7K6A1", "PF3D7_0925700", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695911": { "compartment": "compartment_7660", "id": "reaction_10695911", "reactome": "R-PFA-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10689874" ], "products": [ "species_10695909", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1105000", "Q8IIV2", "PF3D7_1105000", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695894": { "compartment": "compartment_7660", "id": "reaction_10695894", "reactome": "R-PFA-4570485", "name": "SUMOylation of Histone H4 with SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695833", "species_10689874" ], "products": [ "species_10694930", "species_10695891" ], "modifiers": [ [ "species_10695833", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1105000", "PF3D7_0915100", "PF3D7_1105000", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695957": { "compartment": "compartment_7660", "id": "reaction_10695957", "reactome": "R-PFA-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10693554" ], "products": [ "species_10694930", "species_10695955" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0925700", "PF3D7_0915100", "Q7K6A1", "PF3D7_0925700", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695888": { "compartment": "compartment_7660", "id": "reaction_10695888", "reactome": "R-PFA-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695877" ], "products": [ "species_10695886", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1008800", "Q8I444", "PF3D7_0505800", "Q8IJV7", "PF3D7_1008800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695901": { "compartment": "compartment_7660", "id": "reaction_10695901", "reactome": "R-PFA-4570489", "name": "SUMOylation of NOP58 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695653", "species_10695877" ], "products": [ "species_10695898", "species_10694930" ], "modifiers": [ [ "species_10695653", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1008800", "PF3D7_1008800", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695715": { "compartment": "compartment_7660", "id": "reaction_10695715", "reactome": "R-PFA-4085992", "name": "SUMOylation of DAXX with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695018" ], "products": [ "species_10695713", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0807600", "Q8I444", "PF3D7_0505800", "C0H4S8", "PF3D7_0807600", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695633": { "compartment": "compartment_7660", "id": "reaction_10695633", "reactome": "R-PFA-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695614", "species_10694938" ], "products": [ "species_10695630", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I459", "PF3D7_1445900", "Q8IAR1", "PF3D7_1445900", "Q8IL13", "PF3D7_1445900", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I444", "PF3D7_0505800", "Q8IAR1", "PF3D7_1445900", "Q8I459", "PF3D7_1445900", "Q8IL13", "PF3D7_1445900", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695664": { "compartment": "compartment_7660", "id": "reaction_10695664", "reactome": "R-PFA-3900194", "name": "PIAS1 SUMOylates DDX5 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695653", "species_10695635" ], "products": [ "species_10695656", "species_10694930" ], "modifiers": [ [ "species_10695661", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1445900", "PF3D7_1445900", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695694": { "compartment": "compartment_7660", "id": "reaction_10695694", "reactome": "R-PFA-4085331", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695681" ], "products": [ "species_10695689", "species_10694930" ], "modifiers": [ [ "species_10695691", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0627500", "C6KTB1", "PF3D7_0627500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695645": { "compartment": "compartment_7660", "id": "reaction_10695645", "reactome": "R-PFA-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695635" ], "products": [ "species_10695643", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1445900", "Q8I444", "PF3D7_0505800", "Q8IL13", "PF3D7_1445900", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10690843": { "compartment": "compartment_70101", "id": "reaction_10690843", "reactome": "R-PFA-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690808", "species_70106", "species_29368", "species_73473" ], "products": [ "species_29356", "species_10690833", "species_29360" ], "modifiers": [ [ "species_10690840", "catalyst" ] ], "additional_components": [ "Q8I603", "PF3D7_1204300", "Q8I603", "PF3D7_1204300", "Q8I701", "PF3D7_1302600", "species_71067" ] }, "reaction_10690826": { "compartment": "compartment_70101", "id": "reaction_10690826", "reactome": "R-PFA-204647", "name": "DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690814", "species_204635", "species_29360" ], "products": [ "species_70106", "species_10690808", "species_204628", "species_73473" ], "modifiers": [ [ "species_10690821", "catalyst" ] ], "additional_components": [ "Q8I603", "PF3D7_1204300", "Q8I603", "PF3D7_1204300", "Q8ILW8", "PF3D7_1412600" ] }, "reaction_10696630": { "compartment": "compartment_70101", "id": "reaction_10696630", "reactome": "R-PFA-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696605", "species_71284" ], "products": [ "species_353106", "species_10696592" ], "modifiers": [ [ "species_10696622", "catalyst" ], [ "species_10696628", "catalyst" ] ], "additional_components": [ "PF3D7_1451100", "PF3D7_1451100", "Q8ILV7", "PF3D7_1413800", "Q8ILG9", "PF3D7_1429500", "Q8I5N0", "PF3D7_1217800", "PF3D7_0502800" ] }, "reaction_10696603": { "compartment": "compartment_70101", "id": "reaction_10696603", "reactome": "R-PFA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10696592" ], "products": [ "species_71285", "species_10696595" ], "modifiers": [ [ "species_10696600", "catalyst" ] ], "additional_components": [ "PF3D7_1451100", "PF3D7_1451100", "PF3D7_1009000" ] }, "reaction_10699358": { "compartment": "compartment_12045", "id": "reaction_10699358", "reactome": "R-PFA-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_71285", "species_6788758" ], "modifiers": [ [ "species_10699355", "catalyst" ] ], "additional_components": [ "Q8I555", "PF3D7_1236800", "species_216785" ] }, "reaction_10689522": { "compartment": "compartment_12045", "id": "reaction_10689522", "reactome": "R-PFA-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855663" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10689519", "catalyst" ] ], "additional_components": [ "PF3D7_1247300" ] }, "reaction_10689506": { "compartment": "compartment_12045", "id": "reaction_10689506", "reactome": "R-PFA-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855667" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10689503", "catalyst" ] ], "additional_components": [ "PF3D7_1341600" ] }, "reaction_10689514": { "compartment": "compartment_70101", "id": "reaction_10689514", "reactome": "R-PFA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_8855661", "species_29416" ], "modifiers": [ [ "species_10689511", "catalyst" ] ], "additional_components": [ "PF3D7_0624700" ] }, "reaction_10689498": { "compartment": "compartment_17957", "id": "reaction_10689498", "reactome": "R-PFA-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_8855666", "species_76194" ], "modifiers": [ [ "species_10689495", "catalyst" ] ], "additional_components": [ "PF3D7_0615300" ] }, "reaction_10692115": { "compartment": "compartment_12045", "id": "reaction_10692115", "reactome": "R-PFA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449222" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10692112", "catalyst" ] ], "additional_components": [ "Q8IAQ4", "PF3D7_0806400", "O96196", "PF3D7_0211600" ] }, "reaction_10692070": { "compartment": "compartment_12045", "id": "reaction_10692070", "reactome": "R-PFA-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449299" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10692067", "catalyst" ] ], "additional_components": [ "PF3D7_0321200" ] }, "reaction_10695754": { "compartment": "compartment_12045", "id": "reaction_10695754", "reactome": "R-PFA-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419981", "species_29364" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10695751", "catalyst" ] ], "additional_components": [ "PF3D7_1455900" ] }, "reaction_10692078": { "compartment": "compartment_12045", "id": "reaction_10692078", "reactome": "R-PFA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_449221" ], "products": [ "species_110094", "species_449299" ], "modifiers": [ [ "species_10692075", "catalyst" ] ], "additional_components": [ "PF3D7_0109850" ] }, "reaction_10699345": { "compartment": "compartment_70101", "id": "reaction_10699345", "reactome": "R-PFA-6787632", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860" ], "products": [ "species_29356", "species_6787618" ], "modifiers": [ [ "species_10699342", "catalyst" ] ], "additional_components": [ "PF3D7_0813800" ] }, "reaction_10699348": { "compartment": "compartment_70101", "id": "reaction_10699348", "reactome": "R-PFA-6787642", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6787646", "species_29364" ], "products": [ "species_742368", "species_29366" ], "modifiers": [ [ "species_10699334", "catalyst" ] ], "additional_components": [ "A0A143ZXB3", "PF3D7_1014000" ] }, "reaction_10699337": { "compartment": "compartment_70101", "id": "reaction_10699337", "reactome": "R-PFA-6787623", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787618" ], "products": [ "species_6787646" ], "modifiers": [ [ "species_10699334", "catalyst" ] ], "additional_components": [ "A0A143ZXB3", "PF3D7_1014000" ] }, "reaction_10692100": { "compartment": "compartment_70101", "id": "reaction_10692100", "reactome": "R-PFA-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_532204" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10692097", "catalyst" ] ], "additional_components": [ "Q8IDQ3", "PF3D7_1343600" ] }, "reaction_10692127": { "compartment": "compartment_70101", "id": "reaction_10692127", "reactome": "R-PFA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512", "species_29472" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10692124", "catalyst" ] ], "additional_components": [ "Q8IJF3", "PF3D7_1025100" ] }, "reaction_10692062": { "compartment": "compartment_70101", "id": "reaction_10692062", "reactome": "R-PFA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10692059", "catalyst" ] ], "additional_components": [ "PF3D7_1130000" ] }, "reaction_10701400": { "compartment": "compartment_20699", "id": "reaction_10701400", "reactome": "R-PFA-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10701396" ], "products": [ "species_10701398" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IKE6", "PF3D7_1469100", "C0H5D3", "PF3D7_1324700", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IKE6", "PF3D7_1469100", "C0H5D3", "PF3D7_1324700", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701278": { "compartment": "compartment_6791047", "id": "reaction_10701278", "reactome": "R-PFA-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701225", "species_10701274" ], "products": [ "species_10701276" ], "modifiers": [], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203" ] }, "reaction_10701228": { "compartment": "compartment_6791047", "id": "reaction_10701228", "reactome": "R-PFA-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10701223" ], "products": [ "species_29370", "species_10701225" ], "modifiers": [ [ "species_10701223", "catalyst" ] ], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10692738": { "compartment": "compartment_17963", "id": "reaction_10692738", "reactome": "R-PFA-914017", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10692672" ], "products": [ "species_205687", "species_10692736" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10692704": { "compartment": "compartment_17963", "id": "reaction_10692704", "reactome": "R-PFA-914008", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10692672" ], "products": [ "species_10692702", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10692694": { "compartment": "compartment_17963", "id": "reaction_10692694", "reactome": "R-PFA-914006", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10692672" ], "products": [ "species_10692692", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500" ] }, "reaction_10692684": { "compartment": "compartment_17963", "id": "reaction_10692684", "reactome": "R-PFA-914005", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10692672" ], "products": [ "species_10692682", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10696147": { "compartment": "compartment_12045", "id": "reaction_10696147", "reactome": "R-PFA-5173192", "name": "POFUT2 transfers fucose to TSR domain-containing proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696139" ], "products": [ "species_10696118" ], "modifiers": [ [ "species_10696144", "catalyst" ] ], "additional_components": [ "O97267", "PF3D7_0315200", "O97267", "PF3D7_0315200", "PF3D7_0909200" ] }, "reaction_10698145": { "compartment": "compartment_70101", "id": "reaction_10698145", "reactome": "R-PFA-5690159", "name": "USP21 deubiquitinates RIPK1,DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698138" ], "products": [ "species_10698142", "species_10698072" ], "modifiers": [ [ "species_10698138", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8IDK6", "PF3D7_1349300", "Q8IL78", "PF3D7_1439100", "Q8ILU9", "PF3D7_1414700", "Q8IL78", "PF3D7_1439100", "Q8IDK6", "PF3D7_1349300", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ILU9", "PF3D7_1414700", "Q8IDK6", "PF3D7_1349300", "Q8IL78", "PF3D7_1439100" ] }, "reaction_10698720": { "compartment": "compartment_7660", "id": "reaction_10698720", "reactome": "R-PFA-5696960", "name": "USP49 deubiquitinates H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698715" ], "products": [ "species_10698717", "species_10686649" ], "modifiers": [ [ "species_10698715", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8ILU9", "PF3D7_1414700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ILU9", "PF3D7_1414700" ] }, "reaction_10698089": { "compartment": "compartment_70101", "id": "reaction_10698089", "reactome": "R-PFA-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698085", "species_10697200" ], "products": [ "species_10698087" ], "modifiers": [], "additional_components": [ "PF3D7_0527200", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "Q8I3J3", "PF3D7_0527200" ] }, "reaction_10698681": { "compartment": "compartment_70101", "id": "reaction_10698681", "reactome": "R-PFA-5696627", "name": "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698678" ], "products": [ "species_10689710", "species_10689705" ], "modifiers": [ [ "species_10698678", "catalyst" ] ], "additional_components": [ "Q8IDK6", "PF3D7_1349300", "O97313", "PFC1020c", "PF3D7_1349300", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8IDK6", "PF3D7_1349300", "O97313", "PFC1020c" ] }, "reaction_10698126": { "compartment": "compartment_7660", "id": "reaction_10698126", "reactome": "R-PFA-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698121" ], "products": [ "species_10686649", "species_10698123" ], "modifiers": [ [ "species_10698121", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ILU9", "PF3D7_1414700", "Q8ILU9", "PF3D7_1414700" ] }, "reaction_10699197": { "compartment": "compartment_7660", "id": "reaction_10699197", "reactome": "R-PFA-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698740" ], "products": [ "species_10698744", "species_10699194" ], "modifiers": [ [ "species_10698740", "catalyst" ] ], "additional_components": [ "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700", "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700" ] }, "reaction_10698352": { "compartment": "compartment_70101", "id": "reaction_10698352", "reactome": "R-PFA-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689705" ], "products": [ "species_10689703" ], "modifiers": [ [ "species_10686745", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "PF3D7_1368100" ] }, "reaction_10699265": { "compartment": "compartment_7660", "id": "reaction_10699265", "reactome": "R-PFA-6783238", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699261", "species_10699259" ], "products": [ "species_10699263" ], "modifiers": [], "additional_components": [ "PF3D7_1203900", "Q8ILN4", "PF3D7_1421600", "Q8ILN4", "PF3D7_1421600", "Q8I607", "PF3D7_1203900" ] }, "reaction_10702033": { "compartment": "compartment_70101", "id": "reaction_10702033", "reactome": "R-PFA-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701967", "species_113592", "species_10686740" ], "products": [ "species_111294", "species_10701969" ], "modifiers": [ [ "species_10701967", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702039": { "compartment": "compartment_70101", "id": "reaction_10702039", "reactome": "R-PFA-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693374", "species_113592", "species_10686740" ], "products": [ "species_111294", "species_10701971" ], "modifiers": [ [ "species_10693374", "catalyst" ] ], "additional_components": [ "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "PF3D7_1333200" ] }, "reaction_10701991": { "compartment": "compartment_70101", "id": "reaction_10701991", "reactome": "R-PFA-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701965", "species_10701969" ], "products": [ "species_10701989", "species_10701971" ], "modifiers": [], "additional_components": [ "Q8I2U3", "PF3D7_0921000.1", "Q8IJ70", "PF3D7_1033900", "Q8IDD9", "PF3D7_1356300", "Q8I607", "PF3D7_1203900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8I2U3", "PF3D7_0921000.1", "Q8IDD9", "PF3D7_1356300", "Q8I607", "PF3D7_1203900", "Q8IJ70", "PF3D7_1033900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10701895": { "compartment": "compartment_70101", "id": "reaction_10701895", "reactome": "R-PFA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701881", "species_10701879" ], "products": [ "species_10701883", "species_10701893" ], "modifiers": [], "additional_components": [ "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8IDZ6", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDZ6", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10702070": { "compartment": "compartment_70101", "id": "reaction_10702070", "reactome": "R-PFA-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686680" ], "products": [ "species_10686680", "species_10687728" ], "modifiers": [ [ "species_10698177", "catalyst" ] ], "additional_components": [ "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1460400" ] }, "reaction_10702036": { "compartment": "compartment_70101", "id": "reaction_10702036", "reactome": "R-PFA-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701971" ], "products": [ "species_10701967", "species_76577" ], "modifiers": [ [ "species_10701971", "catalyst" ] ], "additional_components": [ "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10701963": { "compartment": "compartment_7660", "id": "reaction_10701963", "reactome": "R-PFA-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686649", "species_10701897" ], "products": [ "species_10701961", "species_113541" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702074": { "compartment": "compartment_70101", "id": "reaction_10702074", "reactome": "R-PFA-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702072" ], "products": [ "species_10686680", "species_10688129" ], "modifiers": [ [ "species_10698177", "catalyst" ] ], "additional_components": [ "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1460400" ] }, "reaction_10702041": { "compartment": "compartment_7660", "id": "reaction_10702041", "reactome": "R-PFA-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701961" ], "products": [ "species_164121", "species_10701993" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500" ] }, "reaction_10702030": { "compartment": "compartment_7660", "id": "reaction_10702030", "reactome": "R-PFA-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686649", "species_10701993" ], "products": [ "species_10701995", "species_113541" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702028": { "compartment": "compartment_7660", "id": "reaction_10702028", "reactome": "R-PFA-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701995", "species_10702007" ], "products": [ "species_10701961", "species_10702026" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "O77397", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8ILW5", "PF3D7_1412900.1", "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8I607", "PF3D7_1203900", "O77397", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8ILW5", "PF3D7_1412900.1", "Q8I2U3", "PF3D7_0921000.1" ] }, "reaction_10702374": { "compartment": "compartment_70101", "id": "reaction_10702374", "reactome": "R-PFA-8865774", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_10691147" ], "products": [ "species_29372", "species_10702344", "species_29370" ], "modifiers": [ [ "species_10702371", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29438", "species_29420", "Q8IJU8", "PF3D7_1147200", "Q8IHP8", "PF3D7_1147200" ] }, "reaction_10688265": { "compartment": "compartment_70101", "id": "reaction_10688265", "reactome": "R-PFA-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111628", "species_70106" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10688271": { "compartment": "compartment_70101", "id": "reaction_10688271", "reactome": "R-PFA-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111627", "species_113592", "species_29472" ], "products": [ "species_111647", "species_29372", "species_29404", "species_29370" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10688255": { "compartment": "compartment_70101", "id": "reaction_10688255", "reactome": "R-PFA-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_76630" ], "products": [ "species_76632", "species_76633" ], "modifiers": [ [ "species_10688252", "catalyst" ] ], "additional_components": [ "species_73524", "Q08210", "PFF0160c" ] }, "reaction_10688268": { "compartment": "compartment_70101", "id": "reaction_10688268", "reactome": "R-PFA-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111647", "species_29448" ], "products": [ "species_111628", "species_29372" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10702131": { "compartment": "compartment_17938", "id": "reaction_10702131", "reactome": "R-PFA-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702126", "species_29356" ], "products": [ "species_29372", "species_10702128" ], "modifiers": [ [ "species_10702126", "catalyst" ] ], "additional_components": [ "species_29438", "C0H516", "PF3D7_0903200", "species_29420", "C0H516", "PF3D7_0903200", "species_29438", "C0H516", "PF3D7_0903200" ] }, "reaction_10702146": { "compartment": "compartment_5683628", "id": "reaction_10702146", "reactome": "R-PFA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702141", "species_29356" ], "products": [ "species_29372", "species_10702143" ], "modifiers": [ [ "species_10702141", "catalyst" ] ], "additional_components": [ "Q8IDL8", "PF3D7_1348100", "species_29438", "Q8IDL8", "PF3D7_1348100", "species_29420", "Q8IDL8", "PF3D7_1348100", "species_29438" ] }, "reaction_10702113": { "compartment": "compartment_17938", "id": "reaction_10702113", "reactome": "R-PFA-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10702102" ], "products": [ "species_29372", "species_10702104" ], "modifiers": [ [ "species_10702102", "catalyst" ], [ "species_10702111", "catalyst" ] ], "additional_components": [ "species_29438", "C0H516", "PF3D7_0903200", "C0H516", "PF3D7_0903200", "species_29420", "species_29438", "C0H516", "PF3D7_0903200", "Q8I379", "PF3D7_1114200", "Q8IIL9", "PF3D7_1114200" ] }, "reaction_10702850": { "compartment": "compartment_17938", "id": "reaction_10702850", "reactome": "R-PFA-8877451", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702823" ], "products": [ "species_10702685", "species_10702831", "species_29420" ], "modifiers": [ [ "species_10702847", "catalyst" ] ], "additional_components": [ "C0H516", "PF3D7_0903200", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "C0H516", "PF3D7_0903200", "species_29438", "Q8IIT1", "PF3D7_1107200", "Q8IDH2", "PF3D7_1352800" ] }, "reaction_10702761": { "compartment": "compartment_171062", "id": "reaction_10702761", "reactome": "R-PFA-8875320", "name": "RAB5 GEFs exchange GTP for GDP on RAB5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702687" ], "products": [ "species_10702685", "species_29420", "species_10702705" ], "modifiers": [ [ "species_10702758", "catalyst" ] ], "additional_components": [ "O96193", "PF3D7_0211200", "Q8I274", "PF3D7_0211200", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "species_29438", "Q8ILY5", "PF3D7_1411000.2", "A0A144A1B7", "PF3D7_1411000.2", "Q8IAZ5", "PF3D7_1411000.2" ] }, "reaction_10702910": { "compartment": "compartment_13946", "id": "reaction_10702910", "reactome": "R-PFA-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702872" ], "products": [ "species_10702685", "species_29420", "species_10702886" ], "modifiers": [ [ "species_10702907", "catalyst" ] ], "additional_components": [ "A0A5K1K8H7", "PF3D7_0513800", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I560", "PF3D7_1236300", "Q8I481", "PF3D7_0501900", "Q8I451", "PF3D7_0505100" ] }, "reaction_10689388": { "compartment": "compartment_17906", "id": "reaction_10689388", "reactome": "R-PFA-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689386" ], "products": [ "species_10689380" ], "modifiers": [], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8I6T6", "PF3D7_1404100" ] }, "reaction_10693609": { "compartment": "compartment_5460", "id": "reaction_10693609", "reactome": "R-PFA-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693598", "species_379721", "species_10693585" ], "products": [ "species_10693606", "species_379697", "species_10693600" ], "modifiers": [ [ "species_10693585", "catalyst" ], [ "species_10693598", "catalyst" ] ], "additional_components": [ "CHEBI:33738", "Q8I5R0", "PF3D7_1214600", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067", "Q8I5R0", "PF3D7_1214600", "CHEBI:33737", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "CHEBI:33739", "Q8IBI5", "PF3D7_0727200", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067", "CHEBI:33738", "Q8I5R0", "PF3D7_1214600" ] }, "reaction_10693614": { "compartment": "compartment_5460", "id": "reaction_10693614", "reactome": "R-PFA-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693612", "species_113531" ], "products": [ "species_10693585" ], "modifiers": [], "additional_components": [ "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067" ] }, "reaction_10693558": { "compartment": "compartment_70101", "id": "reaction_10693558", "reactome": "R-PFA-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_8942986", "species_983036" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10703040": { "compartment": "compartment_70101", "id": "reaction_10703040", "reactome": "R-PFA-8940641", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032" ], "products": [ "species_8955634" ], "modifiers": [ [ "species_10703037", "catalyst" ] ], "additional_components": [ "PF3D7_1005700" ] }, "reaction_10693397": { "compartment": "compartment_70101", "id": "reaction_10693397", "reactome": "R-PFA-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693343", "species_10693394" ], "products": [ "species_10693392", "species_10693345" ], "modifiers": [ [ "species_10693343", "catalyst" ] ], "additional_components": [ "Q8IAW2", "PF3D7_0812600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600" ] }, "reaction_10693403": { "compartment": "compartment_70101", "id": "reaction_10693403", "reactome": "R-PFA-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693351", "species_10693345" ], "products": [ "species_111294", "species_10693343", "species_10693368", "species_76577" ], "modifiers": [ [ "species_10693351", "catalyst" ] ], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10693354": { "compartment": "compartment_70101", "id": "reaction_10693354", "reactome": "R-PFA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693347" ], "products": [ "species_111294", "species_10693343", "species_10693351", "species_76577" ], "modifiers": [ [ "species_10693271", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693370": { "compartment": "compartment_70101", "id": "reaction_10693370", "reactome": "R-PFA-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693368" ], "products": [ "species_983123", "species_10693271" ], "modifiers": [], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693400": { "compartment": "compartment_70101", "id": "reaction_10693400", "reactome": "R-PFA-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10686740", "species_29926", "species_10693392" ], "products": [ "species_111294", "species_29926", "species_10693394", "species_76577" ], "modifiers": [ [ "species_10693392", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10693405": { "compartment": "compartment_70101", "id": "reaction_10693405", "reactome": "R-PFA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983035", "species_10693271", "species_10693345" ], "products": [ "species_10693347" ], "modifiers": [], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693372": { "compartment": "compartment_70101", "id": "reaction_10693372", "reactome": "R-PFA-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_10686740", "species_983032", "species_8942986", "species_983036" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10693366": { "compartment": "compartment_17957", "id": "reaction_10693366", "reactome": "R-PFA-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_983032" ], "products": [ "species_29372", "species_29370", "species_983034" ], "modifiers": [ [ "species_10693363", "catalyst" ] ], "additional_components": [ "Q8IHR3", "PF3D7_1145500" ] }, "reaction_10690798": { "compartment": "compartment_12045", "id": "reaction_10690798", "reactome": "R-PFA-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690794", "species_10690709" ], "products": [ "species_10690796" ], "modifiers": [], "additional_components": [ "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29438", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10694518": { "compartment": "compartment_161320", "id": "reaction_10694518", "reactome": "R-PFA-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10694515", "catalyst" ] ], "additional_components": [ "Q8I6Z5", "PF3D7_1323500", "Q8IIL0", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800" ] }, "reaction_10698337": { "compartment": "compartment_7660", "id": "reaction_10698337", "reactome": "R-PFA-5691004", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698333", "species_10695924", "species_10695861" ], "products": [ "species_10698335" ], "modifiers": [], "additional_components": [ "Q8IJS8", "PF3D7_1011700", "PF3D7_1432600", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8ILD6", "PF3D7_1432600", "Q8IJS8", "PF3D7_1011700" ] }, "reaction_10688851": { "compartment": "compartment_7660", "id": "reaction_10688851", "reactome": "R-PFA-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688847", "species_10688842" ], "products": [ "species_10688849" ], "modifiers": [], "additional_components": [ "PF3D7_1368800", "PF3D7_0203300", "O96136", "PF3D7_0203300", "Q8ID22", "PF3D7_1368800" ] }, "reaction_10688768": { "compartment": "compartment_7660", "id": "reaction_10688768", "reactome": "R-PFA-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688760" ], "products": [ "species_10688765" ], "modifiers": [ [ "species_10688760", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578" ] }, "reaction_10688774": { "compartment": "compartment_7660", "id": "reaction_10688774", "reactome": "R-PFA-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687534", "species_10687529" ], "products": [ "species_10687536" ], "modifiers": [], "additional_components": [ "PF3D7_1369500", "PF3D7_0415500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500" ] }, "reaction_10688725": { "compartment": "compartment_7660", "id": "reaction_10688725", "reactome": "R-PFA-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688723" ], "products": [ "species_10688723" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688756": { "compartment": "compartment_7660", "id": "reaction_10688756", "reactome": "R-PFA-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688749" ], "products": [ "species_113550", "species_10688753" ], "modifiers": [ [ "species_10688749", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688772": { "compartment": "compartment_7660", "id": "reaction_10688772", "reactome": "R-PFA-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688765" ], "products": [ "species_10688770" ], "modifiers": [], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688763": { "compartment": "compartment_7660", "id": "reaction_10688763", "reactome": "R-PFA-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10688753" ], "products": [ "species_10688760", "species_111349" ], "modifiers": [ [ "species_10688753", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688747": { "compartment": "compartment_7660", "id": "reaction_10688747", "reactome": "R-PFA-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688743", "species_10688737", "species_10688723" ], "products": [ "species_10688745" ], "modifiers": [], "additional_components": [ "PF3D7_0610900", "PF3D7_0705000", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688776": { "compartment": "compartment_7660", "id": "reaction_10688776", "reactome": "R-PFA-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687606", "species_10687536" ], "products": [ "species_10687608" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10688751": { "compartment": "compartment_7660", "id": "reaction_10688751", "reactome": "R-PFA-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688745", "species_72084", "species_29428" ], "products": [ "species_10688749" ], "modifiers": [], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10695347": { "compartment": "compartment_70101", "id": "reaction_10695347", "reactome": "R-PFA-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695322", "species_10695339", "species_10695331" ], "products": [ "species_10695318", "species_10695345" ], "modifiers": [], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "PF14_0324", "Q8IL88", "PF3D7_1437900", "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_113582", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10695362": { "compartment": "compartment_70101", "id": "reaction_10695362", "reactome": "R-PFA-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695358", "species_10695360" ], "products": [ "species_10695320" ], "modifiers": [], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10696814": { "compartment": "compartment_70101", "id": "reaction_10696814", "reactome": "R-PFA-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10695345" ], "products": [ "species_10696808" ], "modifiers": [], "additional_components": [ "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_29358", "species_113582", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10695325": { "compartment": "compartment_70101", "id": "reaction_10695325", "reactome": "R-PFA-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695320" ], "products": [ "species_29372", "species_10695322" ], "modifiers": [ [ "species_10695320", "catalyst" ], [ "species_10695318", "catalyst" ] ], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900" ] }, "reaction_10703669": { "compartment": "compartment_70101", "id": "reaction_10703669", "reactome": "R-PFA-9712274", "name": "NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703008", "species_9714134" ], "products": [ "species_10703667" ], "modifiers": [], "additional_components": [ "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10695268": { "compartment": "compartment_17957", "id": "reaction_10695268", "reactome": "R-PFA-3341296", "name": "GPX7,8 catalyze peroxidation of P4HB (PDI)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695241", "species_3341383" ], "products": [ "species_113519", "species_10695252" ], "modifiers": [ [ "species_10695265", "catalyst" ] ], "additional_components": [ "Q8I2V9", "PF3D7_1472600", "Q8IKB2", "PF3D7_1472600", "C0H4Y6", "PF3D7_1472600", "Q8IKB2", "PF3D7_1472600", "Q8I2V9", "PF3D7_1472600", "C0H4Y6", "PF3D7_1472600", "Q8IIC3", "PF3D7_1124000", "Q8I5T2", "PF3D7_1212000" ] }, "reaction_10695227": { "compartment": "compartment_70616", "id": "reaction_10695227", "reactome": "R-PFA-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10689563" ], "products": [ "species_10689561", "species_189461" ], "modifiers": [], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "CHEBI:38574", "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "CHEBI:38573" ] }, "reaction_10698668": { "compartment": "compartment_5460", "id": "reaction_10698668", "reactome": "R-PFA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696199", "species_113521" ], "products": [ "species_5696194", "species_113573" ], "modifiers": [ [ "species_10698665", "catalyst" ] ], "additional_components": [ "PF3D7_0520600" ] }, "reaction_10690238": { "compartment": "compartment_70101", "id": "reaction_10690238", "reactome": "R-PFA-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10690235", "catalyst" ] ], "additional_components": [ "species_29926", "C0H556", "PF3D7_0924300" ] }, "reaction_10690256": { "compartment": "compartment_70101", "id": "reaction_10690256", "reactome": "R-PFA-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73524" ], "products": [ "species_111294", "species_29386" ], "modifiers": [ [ "species_10690253", "catalyst" ] ], "additional_components": [ "PF3D7_1015000" ] }, "reaction_10690266": { "compartment": "compartment_70101", "id": "reaction_10690266", "reactome": "R-PFA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10690263", "catalyst" ] ], "additional_components": [ "Q8IDB3", "PF3D7_1359100", "species_29926" ] }, "reaction_10690356": { "compartment": "compartment_876", "id": "reaction_10690356", "reactome": "R-PFA-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10690353", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10690379": { "compartment": "compartment_70101", "id": "reaction_10690379", "reactome": "R-PFA-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690365", "species_1497805" ], "products": [ "species_10690363", "species_198816" ], "modifiers": [ [ "species_10690365", "catalyst" ] ], "additional_components": [ "species_917877", "Q8I599", "PF3D7_1232300", "CHEBI:36144", "Q8I599", "PF3D7_1232300", "species_917877", "Q8I599", "PF3D7_1232300" ] }, "reaction_10690376": { "compartment": "compartment_70101", "id": "reaction_10690376", "reactome": "R-PFA-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10690363", "species_73473" ], "products": [ "species_10690365", "species_29360" ], "modifiers": [ [ "species_10690373", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "Q8I599", "PF3D7_1232300", "species_917877", "Q8I599", "PF3D7_1232300", "Q8ID33", "PF3D7_1367500", "species_29386" ] }, "reaction_10694965": { "compartment": "compartment_70101", "id": "reaction_10694965", "reactome": "R-PFA-3000238", "name": "LMBRD1 transports lysosomal Cbl to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3000239" ], "products": [ "species_3000241" ], "modifiers": [ [ "species_10694962", "catalyst" ] ], "additional_components": [ "PF3D7_1338000" ] }, "reaction_10693012": { "compartment": "compartment_70101", "id": "reaction_10693012", "reactome": "R-PFA-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10692996" ], "products": [ "species_10693001", "species_29432" ], "modifiers": [ [ "species_10693009", "catalyst" ] ], "additional_components": [ "Q8ID54", "PF3D7_1365400", "species_216785", "species_216785", "Q8ID54", "PF3D7_1365400", "Q8IBI5", "PF3D7_0727200" ] }, "reaction_10690435": { "compartment": "compartment_70616", "id": "reaction_10690435", "reactome": "R-PFA-200720", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671" ], "products": [ "species_111355" ], "modifiers": [ [ "species_10690425", "catalyst" ] ], "additional_components": [ "PF3D7_0811100" ] }, "reaction_10700995": { "compartment": "compartment_70101", "id": "reaction_10700995", "reactome": "R-PFA-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_29372", "species_70106", "species_29370", "species_200640" ], "modifiers": [ [ "species_10700992", "catalyst" ] ], "additional_components": [ "PF3D7_1245000" ] }, "reaction_10690433": { "compartment": "compartment_70101", "id": "reaction_10690433", "reactome": "R-PFA-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690417": { "compartment": "compartment_70101", "id": "reaction_10690417", "reactome": "R-PFA-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10698693": { "compartment": "compartment_5460", "id": "reaction_10698693", "reactome": "R-PFA-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801451", "species_200671", "species_113593" ], "products": [ "species_113548", "species_113581", "species_5389850" ], "modifiers": [ [ "species_10698690", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690437": { "compartment": "compartment_70101", "id": "reaction_10690437", "reactome": "R-PFA-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_200640" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10700997": { "compartment": "compartment_5460", "id": "reaction_10700997", "reactome": "R-PFA-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_5389850" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10698690", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690420": { "compartment": "compartment_70101", "id": "reaction_10690420", "reactome": "R-PFA-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_29356", "species_200640" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10700987": { "compartment": "compartment_5460", "id": "reaction_10700987", "reactome": "R-PFA-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_5693984" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10700984", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10701000": { "compartment": "compartment_5460", "id": "reaction_10701000", "reactome": "R-PFA-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10700984", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690431": { "compartment": "compartment_70101", "id": "reaction_10690431", "reactome": "R-PFA-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29372", "species_29370", "species_111353" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10693026": { "compartment": "compartment_70101", "id": "reaction_10693026", "reactome": "R-PFA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965053" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10693024": { "compartment": "compartment_70101", "id": "reaction_10693024", "reactome": "R-PFA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10693028": { "compartment": "compartment_70101", "id": "reaction_10693028", "reactome": "R-PFA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965131" ], "products": [ "species_29390", "species_29370" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10688410": { "compartment": "compartment_70101", "id": "reaction_10688410", "reactome": "R-PFA-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83962", "species_500244" ], "products": [ "species_29372", "species_500430" ], "modifiers": [ [ "species_10688407", "catalyst" ] ], "additional_components": [ "CHEBI:28542", "species_112016", "CHEBI:16450", "CHEBI:16704", "Q8I3X4", "PF3D7_0513300" ] }, "reaction_10694172": { "compartment": "compartment_70101", "id": "reaction_10694172", "reactome": "R-PFA-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694168", "species_10694166" ], "products": [ "species_10694170" ], "modifiers": [], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IKX4", "PF3D7_1450100", "C6KT56", "PF3D7_0621900", "Q8I613", "PF3D7_1203200", "Q8II00", "PF3D7_1136400", "Q8I5P4", "PF3D7_1216300", "C0H4Q0", "PF3D7_0729000", "Q8IKX4", "PF3D7_1450100", "C6KT56", "PF3D7_0621900", "Q8I613", "PF3D7_1203200", "Q8II00", "PF3D7_1136400", "Q8I5P4", "PF3D7_1216300", "C0H4Q0", "PF3D7_0729000", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200" ] }, "reaction_10696497": { "compartment": "compartment_70101", "id": "reaction_10696497", "reactome": "R-PFA-5263614", "name": "MeSeOH is reduced to MeSeH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357663", "species_70106", "species_29364" ], "products": [ "species_29356", "species_29366", "species_5357669" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "P61076", "PFI1170c", "species_29386" ] }, "reaction_10696500": { "compartment": "compartment_70101", "id": "reaction_10696500", "reactome": "R-PFA-5263616", "name": "MeSeO2H is reduced to MeSeOH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357694", "species_70106", "species_29364" ], "products": [ "species_5357663", "species_29356", "species_29366" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "P61076", "PFI1170c", "species_29386" ] }, "reaction_10696797": { "compartment": "compartment_5263232", "id": "reaction_10696797", "reactome": "R-PFA-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696793", "species_30389" ], "products": [ "species_10696795", "species_10696785" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800", "Q7KQK0", "PF3D7_1223100", "Q7KQK0", "PF3D7_1223100", "species_30389", "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800" ] }, "reaction_10687497": { "compartment": "compartment_70101", "id": "reaction_10687497", "reactome": "R-PFA-71732", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10687494", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "O77392", "PF3D7_0316300.2", "C0H477", "PF3D7_0316300.2" ] }, "reaction_10692143": { "compartment": "compartment_5460", "id": "reaction_10692143", "reactome": "R-PFA-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159450", "species_113521" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10692140", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "C0H477", "PF3D7_0316300.2", "O77392", "PF3D7_0316300.2" ] }, "reaction_10696800": { "compartment": "compartment_70101", "id": "reaction_10696800", "reactome": "R-PFA-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10696902": { "compartment": "compartment_70616", "id": "reaction_10696902", "reactome": "R-PFA-5623643", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623644", "species_5623648", "species_163953" ], "products": [ "species_5623650", "species_5623649" ], "modifiers": [ [ "species_10696899", "catalyst" ] ], "additional_components": [ "PF3D7_0626100" ] }, "reaction_10690305": { "compartment": "compartment_7660", "id": "reaction_10690305", "reactome": "R-PFA-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690301" ], "products": [ "species_10690303" ], "modifiers": [], "additional_components": [ "PF3D7_1113900", "PF3D7_1113900" ] }, "reaction_10701024": { "compartment": "compartment_70101", "id": "reaction_10701024", "reactome": "R-PFA-6803890", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701020" ], "products": [ "species_10701022" ], "modifiers": [], "additional_components": [ "C0H4V6", "PF3D7_1362100", "A0A5K1K948", "PF3D7_1362100", "C0H4V6", "PF3D7_1362100", "A0A5K1K948", "PF3D7_1362100" ] }, "reaction_10689362": { "compartment": "compartment_7660", "id": "reaction_10689362", "reactome": "R-PFA-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689307", "species_10689316" ], "products": [ "species_10689318" ], "modifiers": [], "additional_components": [ "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000" ] }, "reaction_10689339": { "compartment": "compartment_7660", "id": "reaction_10689339", "reactome": "R-PFA-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687608", "species_10688666", "species_10689314" ], "products": [ "species_10688666", "species_10689316" ], "modifiers": [ [ "species_10689314", "catalyst" ] ], "additional_components": [ "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "PF3D7_1012700", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "PF3D7_1012700" ] }, "reaction_10694275": { "compartment": "compartment_7660", "id": "reaction_10694275", "reactome": "R-PFA-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694195": { "compartment": "compartment_7660", "id": "reaction_10694195", "reactome": "R-PFA-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694341": { "compartment": "compartment_7660", "id": "reaction_10694341", "reactome": "R-PFA-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023922" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694335": { "compartment": "compartment_7660", "id": "reaction_10694335", "reactome": "R-PFA-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023940" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694254": { "compartment": "compartment_7660", "id": "reaction_10694254", "reactome": "R-PFA-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694213": { "compartment": "compartment_70101", "id": "reaction_10694213", "reactome": "R-PFA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10694210", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694251": { "compartment": "compartment_70101", "id": "reaction_10694251", "reactome": "R-PFA-1855178", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629756" ], "products": [ "species_1629731" ], "modifiers": [ [ "species_10694248", "catalyst" ] ], "additional_components": [ "species_113526", "Q8I3Y8", "PF3D7_0511800" ] }, "reaction_10694329": { "compartment": "compartment_876", "id": "reaction_10694329", "reactome": "R-PFA-1855222", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10694281", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694338": { "compartment": "compartment_70101", "id": "reaction_10694338", "reactome": "R-PFA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_1629765", "species_29370" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694208": { "compartment": "compartment_70101", "id": "reaction_10694208", "reactome": "R-PFA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694272": { "compartment": "compartment_70101", "id": "reaction_10694272", "reactome": "R-PFA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694298": { "compartment": "compartment_70101", "id": "reaction_10694298", "reactome": "R-PFA-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10694263", "catalyst" ] ], "additional_components": [ "Q8ILG1", "PF3D7_1430300" ] }, "reaction_10694266": { "compartment": "compartment_70101", "id": "reaction_10694266", "reactome": "R-PFA-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10694263", "catalyst" ] ], "additional_components": [ "Q8ILG1", "PF3D7_1430300" ] }, "reaction_10694269": { "compartment": "compartment_70101", "id": "reaction_10694269", "reactome": "R-PFA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694332": { "compartment": "compartment_70101", "id": "reaction_10694332", "reactome": "R-PFA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694241": { "compartment": "compartment_70101", "id": "reaction_10694241", "reactome": "R-PFA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10694238", "catalyst" ] ], "additional_components": [ "species_74016", "Q8IJR0", "PF3D7_1013500" ] }, "reaction_10694288": { "compartment": "compartment_876", "id": "reaction_10694288", "reactome": "R-PFA-1855213", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10694285", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694295": { "compartment": "compartment_12045", "id": "reaction_10694295", "reactome": "R-PFA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10694292", "catalyst" ] ], "additional_components": [ "Q8IJR0", "PF3D7_1013500", "species_74016" ] }, "reaction_10694326": { "compartment": "compartment_876", "id": "reaction_10694326", "reactome": "R-PFA-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10694323", "catalyst" ] ], "additional_components": [ "species_74016", "Q8IJR0", "PF3D7_1013500" ] }, "reaction_10694301": { "compartment": "compartment_70101", "id": "reaction_10694301", "reactome": "R-PFA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10694210", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10701576": { "compartment": "compartment_70101", "id": "reaction_10701576", "reactome": "R-PFA-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701570" ], "products": [ "species_29372", "species_10701574" ], "modifiers": [], "additional_components": [ "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "species_29358", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "Q8I5C4", "PF3D7_1229500", "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "species_113582", "Q8I5C4", "PF3D7_1229500" ] }, "reaction_10701580": { "compartment": "compartment_70101", "id": "reaction_10701580", "reactome": "R-PFA-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701578", "species_113592" ], "products": [ "species_29370", "species_10701570" ], "modifiers": [], "additional_components": [ "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "species_113582", "Q8I5C4", "PF3D7_1229500", "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "species_29358", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "Q8I5C4", "PF3D7_1229500" ] }, "reaction_10701763": { "compartment": "compartment_17963", "id": "reaction_10701763", "reactome": "R-PFA-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_8851233" ], "products": [ "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10701757", "catalyst" ] ], "additional_components": [ "species_110577", "species_29494", "species_29438", "species_30187", "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701760": { "compartment": "compartment_17963", "id": "reaction_10701760", "reactome": "R-PFA-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851226", "species_8851227" ], "modifiers": [ [ "species_10701757", "catalyst" ] ], "additional_components": [ "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_113578", "species_109366", "species_109402", "species_109395", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701792": { "compartment": "compartment_984", "id": "reaction_10701792", "reactome": "R-PFA-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701750": { "compartment": "compartment_984", "id": "reaction_10701750", "reactome": "R-PFA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701747", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701733": { "compartment": "compartment_984", "id": "reaction_10701733", "reactome": "R-PFA-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701730", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701780": { "compartment": "compartment_984", "id": "reaction_10701780", "reactome": "R-PFA-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8851462" ], "products": [ "species_109277", "species_8851461" ], "modifiers": [ [ "species_10701777", "catalyst" ] ], "additional_components": [ "CHEBI:17808", "species_205687", "species_29420", "species_110094", "species_109402", "species_29602", "species_109395", "species_113578", "species_29926", "species_74016", "Q8ILE7", "PF3D7_1431800" ] }, "reaction_10701787": { "compartment": "compartment_528865", "id": "reaction_10701787", "reactome": "R-PFA-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851517", "species_8851509" ], "products": [ "species_8851513", "species_8851518" ], "modifiers": [ [ "species_10701784", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110577", "species_110094", "species_205687", "species_29420", "Q8IE96", "PF3D7_1322000", "species_74016" ] }, "reaction_10701753": { "compartment": "compartment_984", "id": "reaction_10701753", "reactome": "R-PFA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701747", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701736": { "compartment": "compartment_876", "id": "reaction_10701736", "reactome": "R-PFA-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701730", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701743": { "compartment": "compartment_984", "id": "reaction_10701743", "reactome": "R-PFA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936166", "species_109276" ], "products": [ "species_109277", "species_8851092" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_2509836", "species_29438", "species_29494", "species_110577", "species_29358", "CHEBI:17808", "species_113582", "species_205687", "species_29420", "species_110094", "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701773": { "compartment": "compartment_984", "id": "reaction_10701773", "reactome": "R-PFA-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936165" ], "products": [ "species_8851369", "species_109277" ], "modifiers": [ [ "species_10701770", "catalyst" ] ], "additional_components": [ "species_113582", "species_205687", "species_29420", "species_110094", "species_109402", "species_109395", "species_113578", "species_76577", "species_29926", "species_74016", "Q8ILE7", "PF3D7_1431800" ] }, "reaction_10701789": { "compartment": "compartment_984", "id": "reaction_10701789", "reactome": "R-PFA-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10696804": { "compartment": "compartment_876", "id": "reaction_10696804", "reactome": "R-PFA-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691235", "species_10691203" ], "products": [ "species_10696802" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "PF3D7_1348800", "A0A5K1K8L6", "PF3D7_1348800", "C0H553", "PF3D7_0923200" ] }, "reaction_10688530": { "compartment": "compartment_17940", "id": "reaction_10688530", "reactome": "R-PFA-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10688527", "catalyst" ] ], "additional_components": [ "C0H4P0", "PF3D7_0721900", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8IDF7", "PF3D7_1354400", "Q8IKJ0", "PF3D7_1464700", "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10692234": { "compartment": "compartment_70101", "id": "reaction_10692234", "reactome": "R-PFA-450466", "name": "AUF1:mRNA complex is destroyed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692232" ], "products": [], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8I2Y5", "PF3D7_0916700", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10692221": { "compartment": "compartment_70101", "id": "reaction_10692221", "reactome": "R-PFA-450434", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450444", "species_10692215" ], "products": [ "species_10692219" ], "modifiers": [], "additional_components": [ "Q8I2Y5", "PF3D7_0916700", "Q8I2Y5", "PF3D7_0916700" ] }, "reaction_10701160": { "compartment": "compartment_7660", "id": "reaction_10701160", "reactome": "R-PFA-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701156", "species_10689351" ], "products": [ "species_10701158" ], "modifiers": [], "additional_components": [ "Q8IDR5", "PF3D7_1342400", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400", "Q8IDR5", "PF3D7_1342400", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200" ] }, "reaction_10700957": { "compartment": "compartment_876", "id": "reaction_10700957", "reactome": "R-PFA-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700953", "species_10700948" ], "products": [ "species_10700955" ], "modifiers": [], "additional_components": [ "PF3D7_0602500", "PF3D7_1442500", "Q8IL46", "PF3D7_1442500", "C6KSM5", "PF3D7_0602500" ] }, "reaction_10701682": { "compartment": "compartment_70101", "id": "reaction_10701682", "reactome": "R-PFA-8848829", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692652", "species_10686740" ], "products": [ "species_10701679" ], "modifiers": [ [ "species_10692652", "catalyst" ] ], "additional_components": [ "PF3D7_1208800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1208800", "PF3D7_1208800" ] }, "reaction_10694665": { "compartment": "compartment_70101", "id": "reaction_10694665", "reactome": "R-PFA-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_179856" ], "products": [ "species_10694663" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "species_179856", "Q8IIE7", "PF3D7_1121900" ] }, "reaction_10692274": { "compartment": "compartment_5460", "id": "reaction_10692274", "reactome": "R-PFA-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374064", "species_113521" ], "products": [ "species_374061", "species_113585" ], "modifiers": [ [ "species_10692271", "catalyst" ] ], "additional_components": [ "species_1981162", "Q8I384", "PF3D7_0906500" ] }, "reaction_10687249": { "compartment": "compartment_70101", "id": "reaction_10687249", "reactome": "R-PFA-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29468" ], "products": [ "species_29514", "species_29498" ], "modifiers": [ [ "species_10687246", "catalyst" ] ], "additional_components": [ "species_1981162", "Q8I384", "PF3D7_0906500" ] }, "reaction_10690983": { "compartment": "compartment_70101", "id": "reaction_10690983", "reactome": "R-PFA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_204635", "species_353106" ], "modifiers": [ [ "species_10690980", "catalyst" ] ], "additional_components": [ "PF3D7_1129000" ] }, "reaction_10687304": { "compartment": "compartment_70101", "id": "reaction_10687304", "reactome": "R-PFA-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10687301", "catalyst" ] ], "additional_components": [ "PF3D7_1033100" ] }, "reaction_10690975": { "compartment": "compartment_70101", "id": "reaction_10690975", "reactome": "R-PFA-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_353555", "species_76194" ], "modifiers": [ [ "species_10690970", "catalyst" ] ], "additional_components": [ "PF3D7_0713900" ] }, "reaction_10690973": { "compartment": "compartment_70101", "id": "reaction_10690973", "reactome": "R-PFA-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10690970", "catalyst" ] ], "additional_components": [ "PF3D7_0713900" ] }, "reaction_10687283": { "compartment": "compartment_5460", "id": "reaction_10687283", "reactome": "R-PFA-70654", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113585" ], "products": [ "species_31339", "species_113552" ], "modifiers": [ [ "species_10687280", "catalyst" ] ], "additional_components": [ "Q6LFH8", "PFF0435w" ] }, "reaction_10699301": { "compartment": "compartment_70101", "id": "reaction_10699301", "reactome": "R-PFA-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_35305", "species_29364" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10699298", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10699294": { "compartment": "compartment_5460", "id": "reaction_10699294", "reactome": "R-PFA-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10699291", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10687293": { "compartment": "compartment_5460", "id": "reaction_10687293", "reactome": "R-PFA-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10687290", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10690407": { "compartment": "compartment_876", "id": "reaction_10690407", "reactome": "R-PFA-200396", "name": "Creatine transport across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200381", "species_74113" ], "products": [ "species_29916", "species_83910" ], "modifiers": [ [ "species_10690404", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10699868": { "compartment": "compartment_70101", "id": "reaction_10699868", "reactome": "R-PFA-6797956", "name": "SLC44A1 transports Cho from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618" ], "products": [ "species_6798162" ], "modifiers": [ [ "species_10699865", "catalyst" ] ], "additional_components": [ "PF3D7_1431900" ] }, "reaction_10687346": { "compartment": "compartment_5460", "id": "reaction_10687346", "reactome": "R-PFA-70844", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_70836" ], "products": [ "species_70843", "species_113559" ], "modifiers": [ [ "species_10687343", "catalyst" ] ], "additional_components": [ "Q8IKW7", "PF3D7_1450900" ] }, "reaction_10698395": { "compartment": "compartment_5460", "id": "reaction_10698395", "reactome": "R-PFA-5693153", "name": "PPM1K dephosphorylates p-BCKDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698385", "species_113521" ], "products": [ "species_113548", "species_10687333" ], "modifiers": [ [ "species_10698392", "catalyst" ] ], "additional_components": [ "O97227", "PF3D7_0303700", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I0X1", "PF3D7_0504600", "Q8I5A0", "PF3D7_1232200", "species_29386", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I5A0", "PF3D7_1232200", "species_29386", "C0H4T6", "PF3D7_0810300", "species_1981162" ] }, "reaction_10687354": { "compartment": "compartment_5460", "id": "reaction_10687354", "reactome": "R-PFA-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10687351", "catalyst" ] ], "additional_components": [ "PF3D7_1240000" ] }, "reaction_10687336": { "compartment": "compartment_5460", "id": "reaction_10687336", "reactome": "R-PFA-70713", "name": "BCKDH transfers CoA group from CoA-SH to BCAAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_508181" ], "products": [ "species_29362", "species_508261", "species_29376" ], "modifiers": [ [ "species_10687333", "catalyst" ] ], "additional_components": [ "CHEBI:16530", "CHEBI:28654", "CHEBI:17865", "CHEBI:15479", "CHEBI:15487", "CHEBI:15477", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10699863": { "compartment": "compartment_5460", "id": "reaction_10699863", "reactome": "R-PFA-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699853", "species_6793610", "species_2162265" ], "products": [ "species_379705", "species_6793613", "species_10698401" ], "modifiers": [ [ "species_10699860", "catalyst" ] ], "additional_components": [ "PF3D7_1132900", "PF3D7_1132900", "Q8IDQ0", "MAL13P1.220", "CHEBI:49883" ] }, "reaction_10699850": { "compartment": "compartment_5460", "id": "reaction_10699850", "reactome": "R-PFA-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699840", "species_10698401" ], "products": [ "species_10699842", "species_10698403" ], "modifiers": [ [ "species_10699847", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386", "Q8I0X1", "PF3D7_0504600", "Q8IEJ6", "PF3D7_1312600", "O97227", "PF3D7_0303700", "PF3D7_1132900", "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "Q8IEJ6", "PF3D7_1312600", "PF3D7_1132900", "PF3D7_1314600" ] }, "reaction_10699304": { "compartment": "compartment_5460", "id": "reaction_10699304", "reactome": "R-PFA-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784236", "species_113587" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10687396": { "compartment": "compartment_5460", "id": "reaction_10687396", "reactome": "R-PFA-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29362", "species_29376" ], "modifiers": [ [ "species_10687393", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10687406": { "compartment": "compartment_70101", "id": "reaction_10687406", "reactome": "R-PFA-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10687403", "catalyst" ] ], "additional_components": [ "C6S3E6", "PF3D7_1108300" ] }, "reaction_10690627": { "compartment": "compartment_876", "id": "reaction_10690627", "reactome": "R-PFA-203680", "name": "eNOS:NOSIP translocation from caveolae to intracellular compartments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690591" ], "products": [ "species_10690625" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "C0H4E6", "PF3D7_0518000", "C0H4E6", "PF3D7_0518000", "C0H553", "PF3D7_0923200", "species_917877", "species_216785", "species_73524", "species_29386", "species_29870" ] }, "reaction_10690593": { "compartment": "compartment_70101", "id": "reaction_10690593", "reactome": "R-PFA-203553", "name": "eNOS binds NOSIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690589", "species_10690485" ], "products": [ "species_10690591" ], "modifiers": [], "additional_components": [ "PF3D7_0518000", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "C0H4E6", "PF3D7_0518000" ] }, "reaction_10696674": { "compartment": "compartment_7660", "id": "reaction_10696674", "reactome": "R-PFA-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_5358610" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10687076", "catalyst" ] ], "additional_components": [ "PF3D7_1304100" ] }, "reaction_10696707": { "compartment": "compartment_7660", "id": "reaction_10696707", "reactome": "R-PFA-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10696653", "species_10696648" ], "products": [ "species_10696668" ], "modifiers": [], "additional_components": [ "PF3D7_0505500", "PF3D7_1427500", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582" ] }, "reaction_10696672": { "compartment": "compartment_7660", "id": "reaction_10696672", "reactome": "R-PFA-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696668", "species_5358514" ], "products": [ "species_10696670" ], "modifiers": [], "additional_components": [ "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582" ] }, "reaction_10696709": { "compartment": "compartment_7660", "id": "reaction_10696709", "reactome": "R-PFA-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696636", "species_10696641" ], "products": [ "species_10696643" ], "modifiers": [], "additional_components": [ "PF3D7_1117800", "PF3D7_0726300", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800" ] }, "reaction_10696661": { "compartment": "compartment_7660", "id": "reaction_10696661", "reactome": "R-PFA-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687014", "species_10696657", "species_10696643" ], "products": [ "species_10696659" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696683": { "compartment": "compartment_7660", "id": "reaction_10696683", "reactome": "R-PFA-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696679", "species_10696663" ], "products": [ "species_10696681" ], "modifiers": [], "additional_components": [ "PF3D7_0725000", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "Q8IBK1", "PF3D7_0725000", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696666": { "compartment": "compartment_7660", "id": "reaction_10696666", "reactome": "R-PFA-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696659" ], "products": [ "species_10696663" ], "modifiers": [ [ "species_10696659", "catalyst" ] ], "additional_components": [ "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696685": { "compartment": "compartment_7660", "id": "reaction_10696685", "reactome": "R-PFA-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10696670" ], "products": [ "species_113582", "species_10696657" ], "modifiers": [], "additional_components": [ "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10690965": { "compartment": "compartment_70101", "id": "reaction_10690965", "reactome": "R-PFA-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10690953" ], "products": [ "species_10690957", "species_29420" ], "modifiers": [ [ "species_10690962", "catalyst" ] ], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q7KQL3", "PF10_0203", "species_29438", "PF3D7_1442900" ] }, "reaction_10696403": { "compartment": "compartment_171907", "id": "reaction_10696403", "reactome": "R-PFA-5229111", "name": "AP4 transports APP from trans-Golgi network to endosome lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696386" ], "products": [ "species_10696400" ], "modifiers": [ [ "species_10696386", "catalyst" ] ], "additional_components": [ "Q8IIH2", "PF3D7_1119500", "Q8IBF8", "PF3D7_0730200", "Q8IFN5", "PF3D7_0423100", "Q8I3A8", "PF3D7_0904100", "Q8IFN5", "PF3D7_0423100", "Q8IIH2", "PF3D7_1119500", "Q8I3A8", "PF3D7_0904100", "Q8IBF8", "PF3D7_0730200", "Q8IIH2", "PF3D7_1119500", "Q8IBF8", "PF3D7_0730200", "Q8IFN5", "PF3D7_0423100", "Q8I3A8", "PF3D7_0904100" ] }, "reaction_10689478": { "compartment": "compartment_70101", "id": "reaction_10689478", "reactome": "R-PFA-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10689469", "species_10689473" ], "products": [ "species_10689444", "species_10689475" ], "modifiers": [ [ "species_10689469", "catalyst" ] ], "additional_components": [ "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300", "Q8I0P6", "PF3D7_1357000", "species_29420", "Q8I0P6", "PF3D7_1357000", "species_29438", "species_29420", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300" ] }, "reaction_10689471": { "compartment": "compartment_70101", "id": "reaction_10689471", "reactome": "R-PFA-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689467", "species_10689462", "species_10689456" ], "products": [ "species_10689469" ], "modifiers": [], "additional_components": [ "PF3D7_1338300", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300" ] }, "reaction_10689366": { "compartment": "compartment_7660", "id": "reaction_10689366", "reactome": "R-PFA-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688727" ], "products": [ "species_10688727" ], "modifiers": [], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10688732": { "compartment": "compartment_7660", "id": "reaction_10688732", "reactome": "R-PFA-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10688727" ], "products": [ "species_113582", "species_10688729" ], "modifiers": [ [ "species_10688727", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10689360": { "compartment": "compartment_7660", "id": "reaction_10689360", "reactome": "R-PFA-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689305", "species_10688743" ], "products": [ "species_10689307" ], "modifiers": [], "additional_components": [ "PF3D7_1030000", "PF3D7_0610900", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000" ] }, "reaction_10689364": { "compartment": "compartment_7660", "id": "reaction_10689364", "reactome": "R-PFA-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689336" ], "products": [ "species_10689336" ], "modifiers": [], "additional_components": [ "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "C6KSQ9", "PF3D7_0606100", "Q9U0K9", "PF3D7_0407700", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "C6KSQ9", "PF3D7_0606100", "Q9U0K9", "PF3D7_0407700" ] }, "reaction_10689353": { "compartment": "compartment_7660", "id": "reaction_10689353", "reactome": "R-PFA-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689349", "species_10689344" ], "products": [ "species_10689351" ], "modifiers": [], "additional_components": [ "PF3D7_0517400", "PF3D7_1441400", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400" ] }, "reaction_10689133": { "compartment": "compartment_7660", "id": "reaction_10689133", "reactome": "R-PFA-110359", "name": "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689116" ], "products": [ "species_10689130" ], "modifiers": [ [ "species_10689116", "catalyst" ] ], "additional_components": [ "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600" ] }, "reaction_10697443": { "compartment": "compartment_70101", "id": "reaction_10697443", "reactome": "R-PFA-5682377", "name": "LC3 de-lipidation by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697357" ], "products": [ "species_5681998", "species_10697347" ], "modifiers": [ [ "species_10697404", "catalyst" ] ], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "species_1500581", "Q8IJK2", "PF3D7_1019900", "Q8ILS3", "PF3D7_1417300" ] }, "reaction_10697409": { "compartment": "compartment_70101", "id": "reaction_10697409", "reactome": "R-PFA-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697363", "species_10697347" ], "products": [ "species_10697374" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697457": { "compartment": "compartment_5683628", "id": "reaction_10697457", "reactome": "R-PFA-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697357" ], "products": [ "species_10697455" ], "modifiers": [], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "species_1500581", "species_1500581", "Q8IJK2", "PF3D7_1019900" ] }, "reaction_10703360": { "compartment": "compartment_70101", "id": "reaction_10703360", "reactome": "R-PFA-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697365" ], "products": [ "species_10697459" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "C6S3K2", "PF3D7_1470000", "C6S3K2", "PF3D7_1470000", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697367": { "compartment": "compartment_70101", "id": "reaction_10697367", "reactome": "R-PFA-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697361", "species_10697363" ], "products": [ "species_10697365" ], "modifiers": [], "additional_components": [ "PF3D7_1470000", "Q8IIA3", "PF3D7_1126100", "Q8IIA3", "PF3D7_1126100", "C6S3K2", "PF3D7_1470000" ] }, "reaction_10697463": { "compartment": "compartment_70101", "id": "reaction_10697463", "reactome": "R-PFA-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697378" ], "products": [ "species_10697355", "species_10697363" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697461": { "compartment": "compartment_70101", "id": "reaction_10697461", "reactome": "R-PFA-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697374", "species_10697359" ], "products": [ "species_10697376" ], "modifiers": [], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100", "PF3D7_0905700.2", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697381": { "compartment": "compartment_70101", "id": "reaction_10697381", "reactome": "R-PFA-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697376" ], "products": [ "species_10697378" ], "modifiers": [ [ "species_10697376", "catalyst" ] ], "additional_components": [ "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100", "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697407": { "compartment": "compartment_70101", "id": "reaction_10697407", "reactome": "R-PFA-5681987", "name": "LC3 is cleaved by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697391" ], "products": [ "species_10697347" ], "modifiers": [ [ "species_10697404", "catalyst" ] ], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "Q8IJK2", "PF3D7_1019900", "Q8ILS3", "PF3D7_1417300" ] }, "reaction_10703521": { "compartment": "compartment_70101", "id": "reaction_10703521", "reactome": "R-PFA-9641096", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703517", "species_10703502" ], "products": [ "species_10703519" ], "modifiers": [], "additional_components": [ "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600" ] }, "reaction_10703504": { "compartment": "compartment_70101", "id": "reaction_10703504", "reactome": "R-PFA-9641089", "name": "Parkin binds Ub:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703500", "species_10693227" ], "products": [ "species_10703502" ], "modifiers": [], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "PF3D7_0303800", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700" ] }, "reaction_10703543": { "compartment": "compartment_70101", "id": "reaction_10703543", "reactome": "R-PFA-9641109", "name": "PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703541" ], "products": [ "species_10703539", "species_10703523" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700" ] }, "reaction_10703563": { "compartment": "compartment_70101", "id": "reaction_10703563", "reactome": "R-PFA-9641111", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703519" ], "products": [ "species_10703561" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500" ] }, "reaction_10703565": { "compartment": "compartment_70101", "id": "reaction_10703565", "reactome": "R-PFA-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703561" ], "products": [ "species_10703541" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600" ] }, "reaction_10703283": { "compartment": "compartment_70101", "id": "reaction_10703283", "reactome": "R-PFA-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10687116", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10687426": { "compartment": "compartment_70101", "id": "reaction_10687426", "reactome": "R-PFA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10687423", "catalyst" ] ], "additional_components": [ "Q8I5L3", "PF3D7_1219900", "species_71067" ] }, "reaction_10699327": { "compartment": "compartment_70101", "id": "reaction_10699327", "reactome": "R-PFA-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10687116", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10690381": { "compartment": "compartment_70101", "id": "reaction_10690381", "reactome": "R-PFA-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10687423", "catalyst" ] ], "additional_components": [ "Q8I5L3", "PF3D7_1219900", "species_71067" ] }, "reaction_10697188": { "compartment": "compartment_70101", "id": "reaction_10697188", "reactome": "R-PFA-5661256", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5661264", "species_29364" ], "products": [ "species_29366", "species_5661268" ], "modifiers": [ [ "species_10697185", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10692240": { "compartment": "compartment_7660", "id": "reaction_10692240", "reactome": "R-PFA-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692236", "species_450613" ], "products": [ "species_10692238" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10692472": { "compartment": "compartment_7660", "id": "reaction_10692472", "reactome": "R-PFA-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450605", "species_10692247" ], "products": [ "species_10692470" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10692476": { "compartment": "compartment_7660", "id": "reaction_10692476", "reactome": "R-PFA-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692244", "species_517622" ], "products": [ "species_10692474" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10697334": { "compartment": "compartment_70101", "id": "reaction_10697334", "reactome": "R-PFA-5676966", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5687536", "species_71284" ], "products": [ "species_5687529", "species_71285" ], "modifiers": [ [ "species_10697331", "catalyst" ] ], "additional_components": [ "PF3D7_1432700" ] }, "reaction_10694769": { "compartment": "compartment_70101", "id": "reaction_10694769", "reactome": "R-PFA-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_111294", "species_111584" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10694772": { "compartment": "compartment_70101", "id": "reaction_10694772", "reactome": "R-PFA-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_111294", "species_109330" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10694766": { "compartment": "compartment_70101", "id": "reaction_10694766", "reactome": "R-PFA-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_111294", "species_29602" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10702430": { "compartment": "compartment_7660", "id": "reaction_10702430", "reactome": "R-PFA-8866601", "name": "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_8866574" ], "products": [ "species_8866608", "species_8866567" ], "modifiers": [ [ "species_10702427", "catalyst" ], [ "species_29892", "catalyst" ] ], "additional_components": [ "Q8I533", "PF3D7_1239000", "species_216785" ] }, "reaction_10699367": { "compartment": "compartment_5460", "id": "reaction_10699367", "reactome": "R-PFA-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6788802" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10699364", "catalyst" ] ], "additional_components": [ "species_109395", "species_109386", "species_76577", "CHEBI:15918", "species_113582", "CHEBI:16174", "CHEBI:28846", "species_110094", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600" ] }, "reaction_10688358": { "compartment": "compartment_70101", "id": "reaction_10688358", "reactome": "R-PFA-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500071" ], "products": [ "species_29370", "species_500077" ], "modifiers": [ [ "species_10688355", "catalyst" ] ], "additional_components": [ "species_113578", "CHEBI:16192", "species_29420", "CHEBI:28862", "PF3D7_0928900" ] }, "reaction_10699375": { "compartment": "compartment_7660", "id": "reaction_10699375", "reactome": "R-PFA-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6788813" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10699372", "catalyst" ] ], "additional_components": [ "CHEBI:15918", "species_109395", "species_76577", "species_109386", "species_110094", "CHEBI:16174", "CHEBI:28846", "species_113582", "PF3D7_0110900" ] }, "reaction_10688302": { "compartment": "compartment_70101", "id": "reaction_10688302", "reactome": "R-PFA-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355", "species_109382" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10688299", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I1R6", "PF3D7_0417200" ] }, "reaction_10692407": { "compartment": "compartment_5460", "id": "reaction_10692407", "reactome": "R-PFA-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113581", "species_482807" ], "products": [ "species_113593", "species_482803" ], "modifiers": [ [ "species_10692402", "catalyst" ] ], "additional_components": [ "species_110577", "species_29438", "species_500739", "species_29892", "species_29494", "species_110644", "species_30185", "species_30187", "CHEBI:18075", "species_29420", "CHEBI:28850", "CHEBI:28862", "species_205687", "CHEBI:16174", "CHEBI:28846", "species_110094", "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10689211": { "compartment": "compartment_70101", "id": "reaction_10689211", "reactome": "R-PFA-111746", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_10689189" ], "products": [ "species_10689186", "species_111745" ], "modifiers": [ [ "species_10689189", "catalyst" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "PF3D7_0306300" ] }, "reaction_10688312": { "compartment": "compartment_70101", "id": "reaction_10688312", "reactome": "R-PFA-73635", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_499997", "species_113592" ], "products": [ "species_29370", "species_499999" ], "modifiers": [ [ "species_10688309", "catalyst" ] ], "additional_components": [ "species_500742", "species_109366", "CHEBI:28850", "CHEBI:18075", "Q8I4S1", "PF3D7_1251300" ] }, "reaction_10689208": { "compartment": "compartment_70101", "id": "reaction_10689208", "reactome": "R-PFA-111742", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10689186" ], "products": [ "species_29356", "species_8866399", "species_10689189" ], "modifiers": [ [ "species_10689205", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688895": { "compartment": "compartment_70101", "id": "reaction_10688895", "reactome": "R-PFA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788778", "species_113592" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10688890", "catalyst" ] ], "additional_components": [ "species_76577", "species_109395", "CHEBI:15918", "species_109386", "species_113582", "CHEBI:28846", "CHEBI:16174", "species_110094", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600", "Q8I231", "PF3D7_0816900", "Q8IB06", "PF3D7_0816900" ] }, "reaction_10689214": { "compartment": "compartment_70101", "id": "reaction_10689214", "reactome": "R-PFA-111751", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10688320" ], "products": [ "species_10688318", "species_29356", "species_8866399" ], "modifiers": [ [ "species_10689205", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688893": { "compartment": "compartment_70101", "id": "reaction_10688893", "reactome": "R-PFA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_6788778", "species_113592" ], "modifiers": [ [ "species_10688890", "catalyst" ] ], "additional_components": [ "species_113582", "CHEBI:28846", "CHEBI:16174", "species_110094", "species_76577", "species_109395", "CHEBI:15918", "species_109386", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600", "Q8I231", "PF3D7_0816900", "Q8IB06", "PF3D7_0816900" ] }, "reaction_10701181": { "compartment": "compartment_70101", "id": "reaction_10701181", "reactome": "R-PFA-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6806885" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10701178", "catalyst" ] ], "additional_components": [ "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10692419": { "compartment": "compartment_70101", "id": "reaction_10692419", "reactome": "R-PFA-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10692416", "catalyst" ] ], "additional_components": [ "Q8ILZ3", "PF3D7_1410200" ] }, "reaction_10688897": { "compartment": "compartment_70101", "id": "reaction_10688897", "reactome": "R-PFA-110141", "name": "(d)ADP + ADP <=> (d)AMP + ATP (AK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_500087" ], "products": [ "species_500088", "species_113592" ], "modifiers": [ [ "species_10688385", "catalyst" ] ], "additional_components": [ "species_113582", "CHEBI:16174", "species_76577", "species_109386", "PF3D7_0816900" ] }, "reaction_10688906": { "compartment": "compartment_70101", "id": "reaction_10688906", "reactome": "R-PFA-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10688903", "catalyst" ] ], "additional_components": [ "Q8I1T1", "PF3D7_0415600", "Q8IJV6", "PF3D7_1008900" ] }, "reaction_10692362": { "compartment": "compartment_70101", "id": "reaction_10692362", "reactome": "R-PFA-482621", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_482625" ], "products": [ "species_113592", "species_482627" ], "modifiers": [ [ "species_10692357", "catalyst" ] ], "additional_components": [ "species_29892", "species_110644", "species_30185", "species_29494", "species_30187", "species_110577", "species_500739", "species_29438", "species_205687", "CHEBI:28846", "CHEBI:16174", "species_29420", "CHEBI:28850", "CHEBI:28862", "CHEBI:18075", "species_110094", "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10689230": { "compartment": "compartment_70101", "id": "reaction_10689230", "reactome": "R-PFA-111804", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10688320" ], "products": [ "species_10688318", "species_29356", "species_8866399" ], "modifiers": [ [ "species_10689227", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "Q8IJN8", "PF3D7_1405600", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688340": { "compartment": "compartment_70101", "id": "reaction_10688340", "reactome": "R-PFA-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10688337", "catalyst" ] ], "additional_components": [ "Q8ILZ3", "PF3D7_1410200" ] }, "reaction_10702420": { "compartment": "compartment_70101", "id": "reaction_10702420", "reactome": "R-PFA-8866405", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10689186" ], "products": [ "species_29356", "species_8866399", "species_10689189" ], "modifiers": [ [ "species_10689227", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "Q8IJN8", "PF3D7_1405600", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688350": { "compartment": "compartment_7660", "id": "reaction_10688350", "reactome": "R-PFA-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742" ], "modifiers": [ [ "species_10688347", "catalyst" ] ], "additional_components": [ "Q8II92", "PF3D7_1127100" ] }, "reaction_10692257": { "compartment": "compartment_5462", "id": "reaction_10692257", "reactome": "R-PFA-450971", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113526", "species_113600" ], "products": [ "species_113563", "species_113529", "species_29362" ], "modifiers": [ [ "species_10692254", "catalyst" ] ], "additional_components": [ "Q8IKU3", "PF3D7_1453500" ] }, "reaction_10687520": { "compartment": "compartment_5460", "id": "reaction_10687520", "reactome": "R-PFA-71775", "name": "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_113548", "species_113525" ], "products": [ "species_29374", "species_113573", "species_113536" ], "modifiers": [ [ "species_10687517", "catalyst" ] ], "additional_components": [ "Q8IIR8", "PF3D7_1108500", "Q8ILE9", "PF3D7_1431600" ] }, "reaction_10687364": { "compartment": "compartment_5460", "id": "reaction_10687364", "reactome": "R-PFA-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113587", "species_113521" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10687361", "catalyst" ] ], "additional_components": [ "Q8I6U7", "PF3D7_1022500" ] }, "reaction_10687428": { "compartment": "compartment_5460", "id": "reaction_10687428", "reactome": "R-PFA-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_70958", "species_29362", "species_29376" ], "modifiers": [ [ "species_10687393", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10692267": { "compartment": "compartment_5460", "id": "reaction_10692267", "reactome": "R-PFA-450984", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_29938" ], "products": [ "species_113594", "species_113529", "species_113600", "species_29376" ], "modifiers": [ [ "species_10692264", "catalyst" ] ], "additional_components": [ "Q8I6T2", "PF3D7_1345700", "species_1981162" ] }, "reaction_10691918": { "compartment": "compartment_876", "id": "reaction_10691918", "reactome": "R-PFA-444008", "name": "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_114523", "species_74113" ], "products": [ "species_209914", "species_83910", "species_352022" ], "modifiers": [ [ "species_10691915", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10687636": { "compartment": "compartment_7660", "id": "reaction_10687636", "reactome": "R-PFA-72095", "name": "Internal Methylation of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687608" ], "products": [ "species_10687616" ], "modifiers": [ [ "species_10687633", "catalyst" ] ], "additional_components": [ "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I6Z2", "PF3D7_0729500", "Q8I567", "PF3D7_1235500", "Q8I5B2", "PF3D7_1230800" ] }, "reaction_10694523": { "compartment": "compartment_70101", "id": "reaction_10694523", "reactome": "R-PFA-2161500", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161525" ], "products": [ "species_2161185" ], "modifiers": [ [ "species_10694520", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10690615": { "compartment": "compartment_20699", "id": "reaction_10690615", "reactome": "R-PFA-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690542", "species_200993" ], "products": [ "species_10690595" ], "modifiers": [ [ "species_10690612", "catalyst" ] ], "additional_components": [ "PF3D7_0923200", "PF3D7_0923200", "Q8IIK6", "PF3D7_1322500", "A0A143ZYC1", "PF3D7_1322500", "Q8IE90", "PF3D7_1322500" ] }, "reaction_10690550": { "compartment": "compartment_20699", "id": "reaction_10690550", "reactome": "R-PFA-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690544" ], "products": [ "species_10690548" ], "modifiers": [], "additional_components": [ "species_917877", "species_216785", "species_73524", "species_29386", "C0H553", "PF3D7_0923200", "species_29870", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870" ] }, "reaction_10690629": { "compartment": "compartment_20699", "id": "reaction_10690629", "reactome": "R-PFA-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690595" ], "products": [ "species_10690485" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386" ] }, "reaction_10690619": { "compartment": "compartment_70101", "id": "reaction_10690619", "reactome": "R-PFA-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_184174", "species_10690617" ], "products": [ "species_10690542" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "PF3D7_0923200" ] }, "reaction_10693934": { "compartment": "compartment_70101", "id": "reaction_10693934", "reactome": "R-PFA-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364" ], "products": [ "species_1222424", "species_29366" ], "modifiers": [ [ "species_10693929", "catalyst" ] ], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "species_1497857", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10691747": { "compartment": "compartment_70101", "id": "reaction_10691747", "reactome": "R-PFA-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691712", "species_429974" ], "products": [ "species_10691714" ], "modifiers": [], "additional_components": [ "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200" ] }, "reaction_10691745": { "compartment": "compartment_70101", "id": "reaction_10691745", "reactome": "R-PFA-429860", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10691714" ], "products": [ "species_10691716", "species_430004" ], "modifiers": [ [ "species_10691742", "catalyst" ] ], "additional_components": [ "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "Q8IEM5", "PF3D7_1308900", "C6KSR4", "PF3D7_0606600", "Q8IJ85", "PF3D7_1032100", "O97285", "PF3D7_0320800" ] }, "reaction_10689987": { "compartment": "compartment_876", "id": "reaction_10689987", "reactome": "R-PFA-189222", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189049" ], "products": [ "species_29532" ], "modifiers": [ [ "species_10689984", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10689998": { "compartment": "compartment_876", "id": "reaction_10689998", "reactome": "R-PFA-189242", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189246" ], "products": [ "species_189219" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "species_70115", "CHEBI:17118", "species_29532", "CHEBI:17118", "species_70115", "species_29532", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10697522": { "compartment": "compartment_12045", "id": "reaction_10697522", "reactome": "R-PFA-5685649", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697518" ], "products": [ "species_10697520" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10703245": { "compartment": "compartment_12045", "id": "reaction_10703245", "reactome": "R-PFA-8961021", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703241" ], "products": [ "species_10703243" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10703484": { "compartment": "compartment_12045", "id": "reaction_10703484", "reactome": "R-PFA-9624778", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703243" ], "products": [ "species_10703482" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10691053": { "compartment": "compartment_984", "id": "reaction_10691053", "reactome": "R-PFA-374919", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] } }, "collapsed_reaction_dictionary": { "reaction_10697020": { "compartment": "compartment_70101", "id": "reaction_10697020", "reactome": "R-PFA-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10690215", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10686578": { "compartment": "compartment_7660", "id": "reaction_10686578", "reactome": "R-PFA-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686546" ], "products": [ "species_10686556", "species_113582", "species_10686554" ], "modifiers": [ [ "species_10686575", "catalyst" ] ], "additional_components": [ "Q8I469", "PF3D7_0503200", "A0A5K1K8V1", "PF3D7_1334100", "O96237", "PF3D7_0215800", "Q8IC17", "PF3D7_0705300", "Q8I5T7", "PF3D7_1211300", "Q8I615", "PF3D7_1203000", "Q8I3J5", "PF3D7_0527000", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "Q8I5T4", "PF3D7_1211700", "Q8ILR7", "PF3D7_1417800", "Q8I3J5", "PF3D7_0527000", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "Q8I5T4", "PF3D7_1211700", "Q8ILR7", "PF3D7_1417800", "Q8I469", "PF3D7_0503200", "A0A5K1K8V1", "PF3D7_1334100", "O96237", "PF3D7_0215800", "Q8IC17", "PF3D7_0705300", "Q8I5T7", "PF3D7_1211300", "PF3D7_1203000", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10686674": { "compartment": "compartment_7660", "id": "reaction_10686674", "reactome": "R-PFA-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686649", "species_10686554" ], "products": [ "species_10686652" ], "modifiers": [ [ "species_10686671", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "PF3D7_1203000", "PF3D7_1203000", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10686678": { "compartment": "compartment_7660", "id": "reaction_10686678", "reactome": "R-PFA-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686652" ], "products": [ "species_10686676" ], "modifiers": [], "additional_components": [ "PF3D7_1203000", "PF3D7_1203000" ] }, "reaction_10686937": { "compartment": "compartment_70101", "id": "reaction_10686937", "reactome": "R-PFA-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686676" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "PF3D7_1203000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10686976": { "compartment": "compartment_7660", "id": "reaction_10686976", "reactome": "R-PFA-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686544" ], "products": [ "species_10686974", "species_10686542", "species_10686527", "species_10686517" ], "modifiers": [], "additional_components": [ "Q8I3J5", "PF3D7_0527000", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "Q8I5T4", "PF3D7_1211700", "Q8ILR7", "PF3D7_1417800", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "PF3D7_1417800", "PF3D7_1211700", "PF3D7_0527000" ] }, "reaction_10686962": { "compartment": "compartment_7660", "id": "reaction_10686962", "reactome": "R-PFA-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686407" ], "products": [ "species_113582", "species_10686949" ], "modifiers": [ [ "species_10686959", "catalyst" ] ], "additional_components": [ "PF3D7_0503200", "PF3D7_0503200", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IC23", "PF3D7_0704700" ] }, "reaction_10686966": { "compartment": "compartment_7660", "id": "reaction_10686966", "reactome": "R-PFA-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686949" ], "products": [ "species_10686964" ], "modifiers": [], "additional_components": [ "PF3D7_0503200", "PF3D7_0503200" ] }, "reaction_10686972": { "compartment": "compartment_70101", "id": "reaction_10686972", "reactome": "R-PFA-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686970" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I469", "PF3D7_0503200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10691078": { "compartment": "compartment_70101", "id": "reaction_10691078", "reactome": "R-PFA-379464", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9677997", "species_71284" ], "products": [ "species_9677992", "species_174369" ], "modifiers": [ [ "species_10691067", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10703494": { "compartment": "compartment_1598585", "id": "reaction_10703494", "reactome": "R-PFA-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10699285" ], "products": [ "species_10703486", "species_29420" ], "modifiers": [ [ "species_10703491", "catalyst" ] ], "additional_components": [ "Q7KQK6", "PF3D7_1117700", "species_29420", "Q7KQK6", "PF3D7_1117700", "species_29438", "PF3D7_0711500" ] }, "reaction_10703498": { "compartment": "compartment_70101", "id": "reaction_10703498", "reactome": "R-PFA-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10703486" ], "products": [ "species_10703496" ], "modifiers": [], "additional_components": [ "Q7KQK6", "PF3D7_1117700", "species_29438", "Q7KQK6", "PF3D7_1117700", "species_29438" ] }, "reaction_10691051": { "compartment": "compartment_876", "id": "reaction_10691051", "reactome": "R-PFA-374896", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10691300": { "compartment": "compartment_70101", "id": "reaction_10691300", "reactome": "R-PFA-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10691297", "catalyst" ] ], "additional_components": [ "Q8IKD3", "PF3D7_1470500", "Q8I6Z7", "PF3D7_1321500.1", "B3FEM7", "PF3D7_1321600" ] }, "reaction_10691242": { "compartment": "compartment_70101", "id": "reaction_10691242", "reactome": "R-PFA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10691239", "catalyst" ] ], "additional_components": [ "C0H553", "PF3D7_0923200" ] }, "reaction_10699877": { "compartment": "compartment_1222693", "id": "reaction_10699877", "reactome": "R-PFA-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_1629751", "species_29370" ], "modifiers": [ [ "species_10699874", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10703237": { "compartment": "compartment_70101", "id": "reaction_10703237", "reactome": "R-PFA-8959510", "name": "SEPHS2 phosphorylates H2Se to form SELP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357660", "species_29356", "species_113592" ], "products": [ "species_29372", "species_70106", "species_8959518", "species_76577" ], "modifiers": [ [ "species_10703234", "catalyst" ] ], "additional_components": [ "PF3D7_0910400" ] }, "reaction_10694885": { "compartment": "compartment_70101", "id": "reaction_10694885", "reactome": "R-PFA-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694412", "species_10690526", "species_74016" ], "products": [ "species_10694857" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "Q8IKV9", "PF3D7_1451700", "species_74016", "P62203", "PF14_0323", "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700" ] }, "reaction_10695764": { "compartment": "compartment_70101", "id": "reaction_10695764", "reactome": "R-PFA-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695758" ], "products": [ "species_10695762" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700", "species_74016", "Q8IKV9", "PF3D7_1451700", "P62203", "PF14_0323", "Q8IAM8", "PF3D7_0802800", "CHEBI:29034", "species_216785" ] }, "reaction_10695726": { "compartment": "compartment_7660", "id": "reaction_10695726", "reactome": "R-PFA-4411373", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695720" ], "products": [ "species_10695724" ], "modifiers": [], "additional_components": [ "Q7KQK7", "PF3D7_1113900", "Q7KQK7", "PF3D7_1113900" ] }, "reaction_10693951": { "compartment": "compartment_70101", "id": "reaction_10693951", "reactome": "R-PFA-1504193", "name": "Ubiquitinated DVL is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693946" ], "products": [ "species_10686740", "species_10693938" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10693949": { "compartment": "compartment_70101", "id": "reaction_10693949", "reactome": "R-PFA-1504190", "name": "DVL is ubiquitinated by CUL3:KLHL12:RBX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10693942" ], "products": [ "species_10693946" ], "modifiers": [ [ "species_10693942", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10690643": { "compartment": "compartment_7660", "id": "reaction_10690643", "reactome": "R-PFA-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10690340" ], "products": [ "species_113550", "species_10690391" ], "modifiers": [ [ "species_10690640", "catalyst" ] ], "additional_components": [ "Q7KQK7", "PF3D7_1113900", "Q7KQK7", "PF3D7_1113900", "Q8IKS8", "PF3D7_1455100" ] }, "reaction_10690343": { "compartment": "compartment_7660", "id": "reaction_10690343", "reactome": "R-PFA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10690313" ], "products": [ "species_113582", "species_10690338" ], "modifiers": [ [ "species_10690340", "catalyst" ] ], "additional_components": [ "Q8I4W3", "PF3D7_1246900", "Q8I4W3", "PF3D7_1246900", "Q7KQK7", "PF3D7_1113900" ] }, "reaction_10697570": { "compartment": "compartment_7660", "id": "reaction_10697570", "reactome": "R-PFA-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697549" ], "products": [ "species_10697568" ], "modifiers": [], "additional_components": [ "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900" ] }, "reaction_10698160": { "compartment": "compartment_70101", "id": "reaction_10698160", "reactome": "R-PFA-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698156", "species_10695314" ], "products": [ "species_10698158" ], "modifiers": [], "additional_components": [ "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "PF3D7_0201800", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900" ] }, "reaction_10698170": { "compartment": "compartment_70101", "id": "reaction_10698170", "reactome": "R-PFA-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698158", "species_113592" ], "products": [ "species_29370", "species_10698167" ], "modifiers": [ [ "species_10698158", "catalyst" ] ], "additional_components": [ "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900" ] }, "reaction_10697560": { "compartment": "compartment_7660", "id": "reaction_10697560", "reactome": "R-PFA-5687088", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10697538" ], "products": [ "species_113582", "species_10697549" ], "modifiers": [ [ "species_10697557", "catalyst" ] ], "additional_components": [ "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800", "C0H4P1", "PF3D7_0934800" ] }, "reaction_10688929": { "compartment": "compartment_7660", "id": "reaction_10688929", "reactome": "R-PFA-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688922" ], "products": [ "species_10688926", "species_29554" ], "modifiers": [ [ "species_10688922", "catalyst" ] ], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000" ] }, "reaction_10688945": { "compartment": "compartment_7660", "id": "reaction_10688945", "reactome": "R-PFA-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688940" ], "products": [ "species_110223", "species_10688942" ], "modifiers": [ [ "species_10688940", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688966": { "compartment": "compartment_7660", "id": "reaction_10688966", "reactome": "R-PFA-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688963" ], "products": [ "species_5637659", "species_10688942" ], "modifiers": [ [ "species_10688963", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688936": { "compartment": "compartment_7660", "id": "reaction_10688936", "reactome": "R-PFA-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688933" ], "products": [ "species_10688926", "species_110216" ], "modifiers": [ [ "species_10688933", "catalyst" ] ], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000" ] }, "reaction_10688952": { "compartment": "compartment_7660", "id": "reaction_10688952", "reactome": "R-PFA-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688949" ], "products": [ "species_10688942", "species_110225" ], "modifiers": [ [ "species_10688949", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688959": { "compartment": "compartment_7660", "id": "reaction_10688959", "reactome": "R-PFA-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688956" ], "products": [ "species_10688942", "species_30140" ], "modifiers": [ [ "species_10688956", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688990": { "compartment": "compartment_7660", "id": "reaction_10688990", "reactome": "R-PFA-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688987" ], "products": [ "species_10688982", "species_5636006" ], "modifiers": [ [ "species_10688987", "catalyst" ] ], "additional_components": [ "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100" ] }, "reaction_10703130": { "compartment": "compartment_17906", "id": "reaction_10703130", "reactome": "R-PFA-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703122" ], "products": [ "species_10703128" ], "modifiers": [], "additional_components": [ "Q8IHR5", "PF3D7_1145200", "C0H563", "PF3D7_1145200", "Q8IHR5", "PF3D7_1145200", "C0H563", "PF3D7_1145200" ] }, "reaction_10699391": { "compartment": "compartment_984", "id": "reaction_10699391", "reactome": "R-PFA-6789310", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174675", "species_6789319" ], "modifiers": [ [ "species_10699388", "catalyst" ] ], "additional_components": [ "Q8II98", "PF3D7_1126600" ] }, "reaction_10691303": { "compartment": "compartment_70101", "id": "reaction_10691303", "reactome": "R-PFA-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10691295", "catalyst" ] ], "additional_components": [ "Q8IKD3", "PF3D7_1470500", "Q8I6Z7", "PF3D7_1321500.1", "B3FEM7", "PF3D7_1321600" ] }, "reaction_10695969": { "compartment": "compartment_7660", "id": "reaction_10695969", "reactome": "R-PFA-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10687012" ], "products": [ "species_10695967", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF13_0328", "Q8I444", "PF3D7_0505800", "P61074", "PF13_0328", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10696010": { "compartment": "compartment_7660", "id": "reaction_10696010", "reactome": "R-PFA-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10696001" ], "products": [ "species_10696008", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1433500", "Q8ILC8", "PF3D7_1433500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695999": { "compartment": "compartment_7660", "id": "reaction_10695999", "reactome": "R-PFA-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695989" ], "products": [ "species_10695997", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1433500", "Q8I444", "PF3D7_0505800", "Q8ILC8", "PF3D7_1433500", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10696015": { "compartment": "compartment_7660", "id": "reaction_10696015", "reactome": "R-PFA-4641350", "name": "PIAS4 SUMOylates TOP2A with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695835", "species_10695989" ], "products": [ "species_10696013", "species_10694930" ], "modifiers": [ [ "species_10695666", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1433500", "PF3D7_1433500", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10696030": { "compartment": "compartment_7660", "id": "reaction_10696030", "reactome": "R-PFA-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10696020" ], "products": [ "species_10696028", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0510500", "Q8I3Z9", "PF3D7_0510500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10690228": { "compartment": "compartment_70101", "id": "reaction_10690228", "reactome": "R-PFA-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_113592", "species_196786" ], "products": [ "species_111294", "species_196834", "species_76577" ], "modifiers": [ [ "species_10690225", "catalyst" ] ], "additional_components": [ "Q9U0G7", "PF3D7_0412300" ] }, "reaction_10690248": { "compartment": "compartment_70101", "id": "reaction_10690248", "reactome": "R-PFA-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10690245", "catalyst" ] ], "additional_components": [ "Q8IAZ8", "PF3D7_0816100", "species_73524" ] }, "reaction_10694915": { "compartment": "compartment_7660", "id": "reaction_10694915", "reactome": "R-PFA-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10694902", "species_10694897" ], "products": [ "species_164121", "species_113541", "species_10694912" ], "modifiers": [ [ "species_10694897", "catalyst" ] ], "additional_components": [ "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8I444", "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000" ] }, "reaction_10694941": { "compartment": "compartment_7660", "id": "reaction_10694941", "reactome": "R-PFA-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694912", "species_10694930" ], "products": [ "species_10694938", "species_10694897" ], "modifiers": [ [ "species_10694897", "catalyst" ] ], "additional_components": [ "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000" ] }, "reaction_10689122": { "compartment": "compartment_7660", "id": "reaction_10689122", "reactome": "R-PFA-110354", "name": "Displacement of OGG1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689114", "species_10688982" ], "products": [ "species_10689116", "species_10688971" ], "modifiers": [], "additional_components": [ "PF3D7_0305600", "Q8I2Y2", "PF3D7_0917100", "O97240", "PF3D7_0305600", "PF3D7_0917100" ] }, "reaction_10689120": { "compartment": "compartment_7660", "id": "reaction_10689120", "reactome": "R-PFA-110352", "name": "Displacement of NTHL1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688942", "species_10689114" ], "products": [ "species_10689116", "species_10688913" ], "modifiers": [], "additional_components": [ "C6KSY9", "PF3D7_0614800", "PF3D7_0305600", "O97240", "PF3D7_0305600", "PF3D7_0614800" ] }, "reaction_10689126": { "compartment": "compartment_7660", "id": "reaction_10689126", "reactome": "R-PFA-110356", "name": "Displacement of MPG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689114", "species_10689014" ], "products": [ "species_10689116", "species_10688976" ], "modifiers": [], "additional_components": [ "PF3D7_0305600", "Q8IKG6", "PF3D7_1467100", "O97240", "PF3D7_0305600", "PF3D7_1467100" ] }, "reaction_10689124": { "compartment": "compartment_7660", "id": "reaction_10689124", "reactome": "R-PFA-110355", "name": "Displacement of MUTYH glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689005", "species_10689114" ], "products": [ "species_10689116", "species_10689001" ], "modifiers": [], "additional_components": [ "A0A143ZYC4", "PF3D7_1129500", "PF3D7_0305600", "O97240", "PF3D7_0305600", "A0A143ZYC4", "PF3D7_1129500" ] }, "reaction_10689118": { "compartment": "compartment_7660", "id": "reaction_10689118", "reactome": "R-PFA-110349", "name": "Displacement of UNG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688926", "species_10689114" ], "products": [ "species_10689116", "species_10688920" ], "modifiers": [], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "PF3D7_0305600", "O97240", "PF3D7_0305600", "PF3D7_1415000" ] }, "reaction_10694851": { "compartment": "compartment_876", "id": "reaction_10694851", "reactome": "R-PFA-2534365", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10694848", "catalyst" ] ], "additional_components": [ "Q8ILA3", "PF3D7_1436100" ] }, "reaction_10695003": { "compartment": "compartment_7660", "id": "reaction_10695003", "reactome": "R-PFA-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694993" ], "products": [ "species_29478", "species_10694995" ], "modifiers": [ [ "species_10695000", "catalyst" ] ], "additional_components": [ "PF3D7_1211600" ] }, "reaction_10697178": { "compartment": "compartment_7660", "id": "reaction_10697178", "reactome": "R-PFA-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696046" ], "products": [ "species_29478", "species_10694993" ], "modifiers": [ [ "species_10695000", "catalyst" ] ], "additional_components": [ "PF3D7_1211600" ] }, "reaction_10696062": { "compartment": "compartment_7660", "id": "reaction_10696062", "reactome": "R-PFA-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696046", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_10694993", "species_159939" ], "modifiers": [ [ "species_10696059", "catalyst" ] ], "additional_components": [ "Q8IAT4", "PF3D7_0809900" ] }, "reaction_10697164": { "compartment": "compartment_7660", "id": "reaction_10697164", "reactome": "R-PFA-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696441", "species_113671", "species_113685" ], "products": [ "species_10696046", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10696059", "catalyst" ] ], "additional_components": [ "Q8IAT4", "PF3D7_0809900" ] }, "reaction_10695575": { "compartment": "compartment_7660", "id": "reaction_10695575", "reactome": "R-PFA-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10695561" ], "products": [ "species_10695567", "species_5566518" ], "modifiers": [ [ "species_10695572", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "PF3D7_1008000" ] }, "reaction_10696930": { "compartment": "compartment_7660", "id": "reaction_10696930", "reactome": "R-PFA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694993" ], "products": [ "species_77502", "species_10696046" ], "modifiers": [ [ "species_10696443", "catalyst" ] ], "additional_components": [ "PF3D7_1355300" ] }, "reaction_10696961": { "compartment": "compartment_7660", "id": "reaction_10696961", "reactome": "R-PFA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696040" ], "products": [ "species_77502", "species_10696949" ], "modifiers": [ [ "species_10696101", "catalyst" ] ], "additional_components": [ "Q8IIL1", "PF3D7_1115200", "Q8I352", "PF3D7_1115200", "Q8IDE8", "PF3D7_1355300" ] }, "reaction_10696688": { "compartment": "compartment_7660", "id": "reaction_10696688", "reactome": "R-PFA-5423038", "name": "SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10689874" ], "products": [ "species_77502", "species_10694646" ], "modifiers": [ [ "species_10694706", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "PF3D7_0403900" ] }, "reaction_10696104": { "compartment": "compartment_7660", "id": "reaction_10696104", "reactome": "R-PFA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694995" ], "products": [ "species_77502", "species_10696040" ], "modifiers": [ [ "species_10696101", "catalyst" ] ], "additional_components": [ "Q8IIL1", "PF3D7_1115200", "Q8I352", "PF3D7_1115200", "Q8IDE8", "PF3D7_1355300" ] }, "reaction_10696446": { "compartment": "compartment_7660", "id": "reaction_10696446", "reactome": "R-PFA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696046" ], "products": [ "species_77502", "species_10696441" ], "modifiers": [ [ "species_10696443", "catalyst" ], [ "species_10696247", "inhibitor" ] ], "additional_components": [ "PF3D7_1355300" ] }, "reaction_10695392": { "compartment": "compartment_7660", "id": "reaction_10695392", "reactome": "R-PFA-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10689874" ], "products": [ "species_2485002", "species_10695365" ], "modifiers": [ [ "species_10695389", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300", "C0H4A7", "PF3D7_0416400" ] }, "reaction_10696439": { "compartment": "compartment_7660", "id": "reaction_10696439", "reactome": "R-PFA-5229203", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696420" ], "products": [ "species_77502", "species_10696437" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696182": { "compartment": "compartment_7660", "id": "reaction_10696182", "reactome": "R-PFA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10689874" ], "products": [ "species_77502", "species_10696172" ], "modifiers": [ [ "species_10696179", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IHP7", "PF3D7_1147300", "Q8ILK1", "PF3D7_1426200" ] }, "reaction_10696293": { "compartment": "compartment_7660", "id": "reaction_10696293", "reactome": "R-PFA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696273" ], "products": [ "species_77502", "species_10696290" ], "modifiers": [ [ "species_10695008", "catalyst" ] ], "additional_components": [ "PF3D7_1426200" ] }, "reaction_10696219": { "compartment": "compartment_7660", "id": "reaction_10696219", "reactome": "R-PFA-5205820", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696199" ], "products": [ "species_77502", "species_10696216" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696249": { "compartment": "compartment_7660", "id": "reaction_10696249", "reactome": "R-PFA-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696235" ], "products": [ "species_77502", "species_10696247" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696335": { "compartment": "compartment_7660", "id": "reaction_10696335", "reactome": "R-PFA-5225649", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695387", "species_10694995" ], "products": [ "species_10696333" ], "modifiers": [ [ "species_10696321", "inhibitor" ] ], "additional_components": [ "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300", "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300" ] }, "reaction_10697183": { "compartment": "compartment_7660", "id": "reaction_10697183", "reactome": "R-PFA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696172", "species_77087" ], "products": [ "species_77502", "species_10697181" ], "modifiers": [ [ "species_10696179", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IHP7", "PF3D7_1147300", "Q8ILK1", "PF3D7_1426200" ] }, "reaction_10697206": { "compartment": "compartment_70101", "id": "reaction_10697206", "reactome": "R-PFA-5665871", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697198", "species_10686934" ], "products": [ "species_10697200" ], "modifiers": [], "additional_components": [ "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000" ] }, "reaction_10698293": { "compartment": "compartment_70101", "id": "reaction_10698293", "reactome": "R-PFA-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698284", "species_29356" ], "products": [ "species_10698288", "species_10698290" ], "modifiers": [ [ "species_10698284", "catalyst" ] ], "additional_components": [ "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "PF3D7_1313000", "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000" ] }, "reaction_10697204": { "compartment": "compartment_70101", "id": "reaction_10697204", "reactome": "R-PFA-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697193", "species_10697200" ], "products": [ "species_10697202" ], "modifiers": [], "additional_components": [ "PF3D7_1117100", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "Q8IIJ6", "PF3D7_1117100" ] }, "reaction_10698267": { "compartment": "compartment_70101", "id": "reaction_10698267", "reactome": "R-PFA-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698262" ], "products": [ "species_1131871", "species_10698264" ], "modifiers": [ [ "species_10698262", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400" ] }, "reaction_10687165": { "compartment": "compartment_70101", "id": "reaction_10687165", "reactome": "R-PFA-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10687122", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10687018": { "compartment": "compartment_7660", "id": "reaction_10687018", "reactome": "R-PFA-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10687005", "species_10687014" ], "products": [ "species_113582", "species_10687016" ], "modifiers": [], "additional_components": [ "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "P61074", "PF13_0328", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10687007": { "compartment": "compartment_7660", "id": "reaction_10687007", "reactome": "R-PFA-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686939", "species_10687003" ], "products": [ "species_10687005" ], "modifiers": [], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10687022": { "compartment": "compartment_7660", "id": "reaction_10687022", "reactome": "R-PFA-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687016" ], "products": [ "species_10687020", "species_10687003" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100" ] }, "reaction_10687059": { "compartment": "compartment_7660", "id": "reaction_10687059", "reactome": "R-PFA-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687055", "species_10687050" ], "products": [ "species_10687057" ], "modifiers": [], "additional_components": [ "PF3D7_1333900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "A0A5K1K9F2", "PF3D7_1333900" ] }, "reaction_10687071": { "compartment": "compartment_7660", "id": "reaction_10687071", "reactome": "R-PFA-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687061" ], "products": [ "species_10687063" ], "modifiers": [ [ "species_10687068", "catalyst" ] ], "additional_components": [ "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "PFD0420c" ] }, "reaction_10687079": { "compartment": "compartment_7660", "id": "reaction_10687079", "reactome": "R-PFA-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10687076", "catalyst" ] ], "additional_components": [ "PF3D7_1304100" ] }, "reaction_10687046": { "compartment": "compartment_7660", "id": "reaction_10687046", "reactome": "R-PFA-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687042" ], "products": [ "species_10687044" ], "modifiers": [], "additional_components": [ "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10689433": { "compartment": "compartment_70101", "id": "reaction_10689433", "reactome": "R-PFA-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689420", "species_10689429" ], "products": [ "species_10689431" ], "modifiers": [], "additional_components": [ "PF3D7_1004000", "Q8I5H4", "PF3D7_1224300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8I5H4", "PF3D7_1224300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJZ7", "PF3D7_1004000" ] }, "reaction_10689437": { "compartment": "compartment_70101", "id": "reaction_10689437", "reactome": "R-PFA-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688213" ], "products": [ "species_10688008", "species_10689435" ], "modifiers": [], "additional_components": [ "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "PF3D7_1004000", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200" ] }, "reaction_10698371": { "compartment": "compartment_70101", "id": "reaction_10698371", "reactome": "R-PFA-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29418", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1981162" ], "modifiers": [ [ "species_10698368", "catalyst" ] ], "additional_components": [ "PF3D7_0727800" ] }, "reaction_10691233": { "compartment": "compartment_114521", "id": "reaction_10691233", "reactome": "R-PFA-418365", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427899", "species_74016" ], "products": [ "species_70106", "species_139827" ], "modifiers": [ [ "species_10691230", "catalyst" ] ], "additional_components": [ "Q76NN8", "PF3D7_1211900", "A0A143ZZK9", "PF3D7_1211900" ] }, "reaction_10693014": { "compartment": "compartment_70101", "id": "reaction_10693014", "reactome": "R-PFA-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_947588", "species_113592" ], "products": [ "species_29372", "species_29370", "species_947594" ], "modifiers": [ [ "species_10692986", "catalyst" ] ], "additional_components": [ "species_1500646", "species_1500581", "species_1500581", "species_1500646", "Q8IKF1", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600" ] }, "reaction_10691562": { "compartment": "compartment_12045", "id": "reaction_10691562", "reactome": "R-PFA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_74016" ], "products": [ "species_70106", "species_111875" ], "modifiers": [ [ "species_10691559", "catalyst" ] ], "additional_components": [ "Q76NN8", "PF3D7_1211900", "A0A143ZZK9", "PF3D7_1211900" ] }, "reaction_10691208": { "compartment": "compartment_876", "id": "reaction_10691208", "reactome": "R-PFA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10691205", "catalyst" ] ], "additional_components": [ "A0A5K1K8L6", "PF3D7_1348800" ] }, "reaction_10698376": { "compartment": "compartment_70101", "id": "reaction_10698376", "reactome": "R-PFA-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5692450" ], "products": [ "species_29372", "species_29370", "species_5692484" ], "modifiers": [ [ "species_10698373", "catalyst" ] ], "additional_components": [ "PF3D7_0516100" ] }, "reaction_10696494": { "compartment": "compartment_70101", "id": "reaction_10696494", "reactome": "R-PFA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5252122", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5252016" ], "modifiers": [ [ "species_10696491", "catalyst" ] ], "additional_components": [ "Q8I3U7", "PF3D7_0516100" ] }, "reaction_10699216": { "compartment": "compartment_7660", "id": "reaction_10699216", "reactome": "R-PFA-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699209", "species_6781829" ], "products": [ "species_10699213", "species_113541" ], "modifiers": [ [ "species_10699209", "catalyst" ] ], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10699211": { "compartment": "compartment_7660", "id": "reaction_10699211", "reactome": "R-PFA-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687612", "species_10688666", "species_5688114" ], "products": [ "species_10699209" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10691010": { "compartment": "compartment_70101", "id": "reaction_10691010", "reactome": "R-PFA-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691000" ], "products": [ "species_10691008" ], "modifiers": [], "additional_components": [ "Q8IHR4", "PF3D7_1218500", "Q8IJ32", "PF3D7_1218500", "Q8I5M3", "PF3D7_1218500", "Q8I5M3", "PF3D7_1218500", "Q8IJ32", "PF3D7_1218500", "Q8IHR4", "PF3D7_1218500" ] }, "reaction_10690941": { "compartment": "compartment_7660", "id": "reaction_10690941", "reactome": "R-PFA-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690937", "species_29428" ], "products": [ "species_10690939" ], "modifiers": [], "additional_components": [ "Q8I616", "PF3D7_1202900", "Q8I616", "PF3D7_1202900" ] }, "reaction_10703624": { "compartment": "compartment_70101", "id": "reaction_10703624", "reactome": "R-PFA-9661417", "name": "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5679042" ], "products": [ "species_29372", "species_5679034", "species_29370" ], "modifiers": [ [ "species_10692753", "catalyst" ] ], "additional_components": [ "CHEBI:18392", "CHEBI:16427", "CHEBI:16427", "CHEBI:18392", "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690066": { "compartment": "compartment_5460", "id": "reaction_10690066", "reactome": "R-PFA-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_70958", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10690063", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "Q8I4X1", "PF3D7_1246100" ] }, "reaction_10690082": { "compartment": "compartment_70101", "id": "reaction_10690082", "reactome": "R-PFA-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10690035", "catalyst" ] ], "additional_components": [ "C6KSS1", "PF3D7_0607300" ] }, "reaction_10690018": { "compartment": "compartment_17927", "id": "reaction_10690018", "reactome": "R-PFA-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189411" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10690015", "catalyst" ] ], "additional_components": [ "Q8IHU1", "PF3D7_1142400" ] }, "reaction_10690080": { "compartment": "compartment_70101", "id": "reaction_10690080", "reactome": "R-PFA-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190173", "species_10690045" ], "products": [ "species_10690078", "species_29426" ], "modifiers": [], "additional_components": [ "species_216785", "Q8IL68", "PF3D7_1440300", "species_216785", "Q8IL68", "PF3D7_1440300", "species_391232" ] }, "reaction_10690048": { "compartment": "compartment_70101", "id": "reaction_10690048", "reactome": "R-PFA-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_29356", "species_70106", "species_189464" ], "modifiers": [ [ "species_10690045", "catalyst" ] ], "additional_components": [ "species_216785", "Q8IL68", "PF3D7_1440300" ] }, "reaction_10690038": { "compartment": "compartment_70101", "id": "reaction_10690038", "reactome": "R-PFA-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_189455", "species_113528" ], "modifiers": [ [ "species_10690035", "catalyst" ] ], "additional_components": [ "C6KSS1", "PF3D7_0607300" ] }, "reaction_10694949": { "compartment": "compartment_5460", "id": "reaction_10694949", "reactome": "R-PFA-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189444", "species_2162257", "species_113521" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10694946", "catalyst" ] ], "additional_components": [ "PF3D7_0519300" ] }, "reaction_10692756": { "compartment": "compartment_876", "id": "reaction_10692756", "reactome": "R-PFA-917979", "name": "ABCG2 tetramer transports heme from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_71185" ], "products": [ "species_29372", "species_917877", "species_29370" ], "modifiers": [ [ "species_10692753", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690008": { "compartment": "compartment_70101", "id": "reaction_10690008", "reactome": "R-PFA-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_189464" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10690005", "catalyst" ] ], "additional_components": [ "Q8I5V3", "PF3D7_1209600", "CHEBI:36319" ] }, "reaction_10694957": { "compartment": "compartment_5460", "id": "reaction_10694957", "reactome": "R-PFA-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10694954", "catalyst" ] ], "additional_components": [ "PF3D7_1435000" ] }, "reaction_10690028": { "compartment": "compartment_17927", "id": "reaction_10690028", "reactome": "R-PFA-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10690025", "catalyst" ] ], "additional_components": [ "Q8IJC3", "PF3D7_1028100", "species_29386" ] }, "reaction_10690076": { "compartment": "compartment_5460", "id": "reaction_10690076", "reactome": "R-PFA-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_113529", "species_189444" ], "modifiers": [ [ "species_10690073", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "Q8ID58", "PF3D7_1364900" ] }, "reaction_10689488": { "compartment": "compartment_70101", "id": "reaction_10689488", "reactome": "R-PFA-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689484", "species_29438" ], "products": [ "species_10689486" ], "modifiers": [], "additional_components": [ "PF3D7_1451100", "species_29438", "Q8IKW5", "PF3D7_1451100" ] }, "reaction_10701428": { "compartment": "compartment_20699", "id": "reaction_10701428", "reactome": "R-PFA-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696892", "species_10701424" ], "products": [ "species_10701426" ], "modifiers": [], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10701434": { "compartment": "compartment_20699", "id": "reaction_10701434", "reactome": "R-PFA-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701274", "species_10701430" ], "products": [ "species_10701432" ], "modifiers": [], "additional_components": [ "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700" ] }, "reaction_10701439": { "compartment": "compartment_20699", "id": "reaction_10701439", "reactome": "R-PFA-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701213", "species_10701422" ], "products": [ "species_10701424" ], "modifiers": [], "additional_components": [ "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800" ] }, "reaction_10701437": { "compartment": "compartment_20699", "id": "reaction_10701437", "reactome": "R-PFA-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10701426" ], "products": [ "species_29420", "species_10701430" ], "modifiers": [ [ "species_10701426", "catalyst" ] ], "additional_components": [ "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10701485": { "compartment": "compartment_12045", "id": "reaction_10701485", "reactome": "R-PFA-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10701483", "species_10698587" ], "products": [ "species_10701481" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "C0H5E1", "PF3D7_1326800", "A0A5K1K9E7", "PF3D7_1316800", "O97323", "PF3D7_0320100", "O77313", "PF3D7_0303000", "C0H5E1", "PF3D7_1326800", "A0A5K1K9E7", "PF3D7_1316800", "O77313", "PF3D7_0303000", "O97323", "PF3D7_0320100", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10694883": { "compartment": "compartment_70101", "id": "reaction_10694883", "reactome": "R-PFA-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694861" ], "products": [ "species_10694881" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700", "species_74016", "Q8IKV9", "PF3D7_1451700", "P62203", "PF14_0323", "Q8IAM8", "PF3D7_0802800", "CHEBI:29034", "species_216785" ] }, "reaction_10702926": { "compartment": "compartment_7660", "id": "reaction_10702926", "reactome": "R-PFA-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10702912" ], "products": [ "species_113582", "species_10702923" ], "modifiers": [ [ "species_10692168", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600", "Q8I239", "PF3D7_0110600", "PF3D7_0724600" ] }, "reaction_10701516": { "compartment": "compartment_7660", "id": "reaction_10701516", "reactome": "R-PFA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_29358" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10701513", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10701668": { "compartment": "compartment_70101", "id": "reaction_10701668", "reactome": "R-PFA-8848338", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10701665", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10689972": { "compartment": "compartment_5460", "id": "reaction_10689972", "reactome": "R-PFA-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_31649", "species_188451" ], "modifiers": [ [ "species_10689969", "catalyst" ] ], "additional_components": [ "PF3D7_0306400" ] }, "reaction_10701673": { "compartment": "compartment_70101", "id": "reaction_10701673", "reactome": "R-PFA-8848339", "name": "PNPLA5 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10701670", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10701676": { "compartment": "compartment_70101", "id": "reaction_10701676", "reactome": "R-PFA-8848355", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2534407" ], "products": [ "species_8848337", "species_30209" ], "modifiers": [ [ "species_10701665", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10697441": { "compartment": "compartment_70101", "id": "reaction_10697441", "reactome": "R-PFA-5682285", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5682283", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5229279" ], "modifiers": [ [ "species_10697438", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693632": { "compartment": "compartment_876", "id": "reaction_10693632", "reactome": "R-PFA-1369052", "name": "ABCAs mediate lipid influx", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_29356", "species_113592" ], "products": [ "species_29372", "species_176478", "species_29370" ], "modifiers": [ [ "species_10693627", "catalyst" ] ], "additional_components": [] }, "reaction_10690928": { "compartment": "compartment_876", "id": "reaction_10690928", "reactome": "R-PFA-266082", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_216762", "species_113592" ], "products": [ "species_29372", "species_29370", "species_171095" ], "modifiers": [ [ "species_10690925", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690921": { "compartment": "compartment_876", "id": "reaction_10690921", "reactome": "R-PFA-265783", "name": "ABCG5:ABCG8 transports sterols from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_265784", "species_113592" ], "products": [ "species_29372", "species_29370", "species_265781" ], "modifiers": [ [ "species_10690918", "catalyst" ] ], "additional_components": [ "CHEBI:26125", "species_171149", "CHEBI:26125", "species_171149", "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10701647": { "compartment": "compartment_70101", "id": "reaction_10701647", "reactome": "R-PFA-8848053", "name": "ABCA5 transports CHOL from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_8848047" ], "products": [ "species_29372", "species_176478", "species_29370" ], "modifiers": [ [ "species_10701644", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693647": { "compartment": "compartment_70101", "id": "reaction_10693647", "reactome": "R-PFA-1454928", "name": "ABCG4 may mediate cholesterol efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176478", "species_29356", "species_113592" ], "products": [ "species_171149", "species_29372", "species_29370" ], "modifiers": [ [ "species_10693644", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10693630": { "compartment": "compartment_876", "id": "reaction_10693630", "reactome": "R-PFA-1369028", "name": "ABCAs mediate lipid efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_176478", "species_113592" ], "products": [ "species_171149", "species_29372", "species_29370" ], "modifiers": [ [ "species_10693627", "catalyst" ] ], "additional_components": [] }, "reaction_10697468": { "compartment": "compartment_2133233", "id": "reaction_10697468", "reactome": "R-PFA-5683714", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5684863" ], "products": [ "species_29372", "species_29370", "species_5684869" ], "modifiers": [ [ "species_10697465", "catalyst" ] ], "additional_components": [ "species_194276", "species_1483256", "species_194276", "species_1483256", "PF3D7_0319700" ] }, "reaction_10696352": { "compartment": "compartment_70101", "id": "reaction_10696352", "reactome": "R-PFA-5227009", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696348", "species_10687881" ], "products": [ "species_10696350" ], "modifiers": [], "additional_components": [ "PF3D7_1121700", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IIE9", "PF3D7_1121700" ] }, "reaction_10693652": { "compartment": "compartment_876", "id": "reaction_10693652", "reactome": "R-PFA-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1131652" ], "products": [ "species_29372", "species_29370", "species_1467459" ], "modifiers": [ [ "species_10693649", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10696331": { "compartment": "compartment_70101", "id": "reaction_10696331", "reactome": "R-PFA-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5223341" ], "products": [ "species_5223344", "species_29372", "species_29370" ], "modifiers": [ [ "species_10696328", "catalyst" ] ], "additional_components": [ "Q8IHR3", "PF3D7_1145500" ] }, "reaction_10693657": { "compartment": "compartment_74000", "id": "reaction_10693657", "reactome": "R-PFA-1467466", "name": "ABCA4 mediates atRAL transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_2466098" ], "products": [ "species_29372", "species_29370", "species_975622" ], "modifiers": [ [ "species_10693654", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693640": { "compartment": "compartment_70101", "id": "reaction_10693640", "reactome": "R-PFA-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1454930" ], "products": [ "species_29372", "species_29370", "species_1454919" ], "modifiers": [ [ "species_10693637", "catalyst" ] ], "additional_components": [ "PF3D7_0112200" ] }, "reaction_10697434": { "compartment": "compartment_70101", "id": "reaction_10697434", "reactome": "R-PFA-5682101", "name": "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10697425" ], "products": [ "species_29370", "species_10697431" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "O97278", "PF3D7_0319700", "O97278", "PF3D7_0319700", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10697436": { "compartment": "compartment_12045", "id": "reaction_10697436", "reactome": "R-PFA-5682103", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697421" ], "products": [ "species_10697425" ], "modifiers": [], "additional_components": [ "O97278", "PF3D7_0319700", "O97278", "PF3D7_0319700" ] }, "reaction_10690889": { "compartment": "compartment_984", "id": "reaction_10690889", "reactome": "R-PFA-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_194276" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10690886", "catalyst" ] ], "additional_components": [ "PF3D7_0629300" ] }, "reaction_10692450": { "compartment": "compartment_876", "id": "reaction_10692450", "reactome": "R-PFA-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10692447", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692436": { "compartment": "compartment_876", "id": "reaction_10692436", "reactome": "R-PFA-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10692433", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800", "C0H4T7", "PF3D7_0810400" ] }, "reaction_10692452": { "compartment": "compartment_876", "id": "reaction_10692452", "reactome": "R-PFA-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10692447", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692443": { "compartment": "compartment_876", "id": "reaction_10692443", "reactome": "R-PFA-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10692433", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800", "C0H4T7", "PF3D7_0810400" ] }, "reaction_10692441": { "compartment": "compartment_876", "id": "reaction_10692441", "reactome": "R-PFA-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10692438", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692445": { "compartment": "compartment_876", "id": "reaction_10692445", "reactome": "R-PFA-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10692438", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691955": { "compartment": "compartment_876", "id": "reaction_10691955", "reactome": "R-PFA-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691952", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691777": { "compartment": "compartment_876", "id": "reaction_10691777", "reactome": "R-PFA-432065", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10691774", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691802": { "compartment": "compartment_70101", "id": "reaction_10691802", "reactome": "R-PFA-432232", "name": "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10691795" ], "products": [ "species_29370", "species_10691799" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400", "C0H4T7", "PF3D7_0810400", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10703161": { "compartment": "compartment_70101", "id": "reaction_10703161", "reactome": "R-PFA-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10689282" ], "products": [ "species_10689284" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "species_30389" ] }, "reaction_10691769": { "compartment": "compartment_876", "id": "reaction_10691769", "reactome": "R-PFA-432054", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10689288": { "compartment": "compartment_70101", "id": "reaction_10689288", "reactome": "R-PFA-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689284" ], "products": [ "species_10689286", "species_10689280" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "species_30389", "species_30389", "Q7KQK0", "PF3D7_1223100", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10691784": { "compartment": "compartment_876", "id": "reaction_10691784", "reactome": "R-PFA-432067", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691781", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691757": { "compartment": "compartment_876", "id": "reaction_10691757", "reactome": "R-PFA-432010", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691767": { "compartment": "compartment_876", "id": "reaction_10691767", "reactome": "R-PFA-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10691764", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691791": { "compartment": "compartment_876", "id": "reaction_10691791", "reactome": "R-PFA-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10691788", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10696562": { "compartment": "compartment_70101", "id": "reaction_10696562", "reactome": "R-PFA-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10696559", "catalyst" ] ], "additional_components": [ "PF3D7_1304200.2" ] }, "reaction_10696578": { "compartment": "compartment_70101", "id": "reaction_10696578", "reactome": "R-PFA-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696575", "catalyst" ] ], "additional_components": [ "PF3D7_0107700" ] }, "reaction_10696554": { "compartment": "compartment_70101", "id": "reaction_10696554", "reactome": "R-PFA-5336453", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696551", "catalyst" ] ], "additional_components": [ "A0A144A2U1", "PF3D7_1467000", "Q8IBA9", "PF3D7_1467000" ] }, "reaction_10696573": { "compartment": "compartment_70101", "id": "reaction_10696573", "reactome": "R-PFA-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696570", "catalyst" ] ], "additional_components": [ "PF3D7_0107700" ] }, "reaction_10693563": { "compartment": "compartment_70101", "id": "reaction_10693563", "reactome": "R-PFA-1247649", "name": "AQP1 tetramer transports CO2 from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113528" ], "products": [ "species_1237009" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691843": { "compartment": "compartment_876", "id": "reaction_10691843", "reactome": "R-PFA-435349", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_435347" ], "products": [ "species_70106", "species_71067" ], "modifiers": [ [ "species_10691840", "catalyst" ] ], "additional_components": [ "PF3D7_0523800" ] }, "reaction_10691859": { "compartment": "compartment_876", "id": "reaction_10691859", "reactome": "R-PFA-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10691856", "catalyst" ] ], "additional_components": [ "PF3D7_1439000" ] }, "reaction_10691873": { "compartment": "compartment_876", "id": "reaction_10691873", "reactome": "R-PFA-442422", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10691870", "catalyst" ] ], "additional_components": [ "C6KST8", "PF3D7_0609100" ] }, "reaction_10691851": { "compartment": "compartment_20699", "id": "reaction_10691851", "reactome": "R-PFA-437136", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10691848", "catalyst" ] ], "additional_components": [ "PF3D7_0715900" ] }, "reaction_10691838": { "compartment": "compartment_172574", "id": "reaction_10691838", "reactome": "R-PFA-435171", "name": "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_445829" ], "products": [ "species_445832", "species_1470067" ], "modifiers": [ [ "species_10691835", "catalyst" ] ], "additional_components": [ "species_216785", "species_71067", "species_1981162", "species_216785", "species_1981162", "species_71067", "PF3D7_0523800" ] }, "reaction_10691830": { "compartment": "compartment_876", "id": "reaction_10691830", "reactome": "R-PFA-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_446589" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10691827", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:641", "CHEBI:6801", "CHEBI:16737", "CHEBI:8428", "CHEBI:42820", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "CHEBI:6801", "O96209", "PF3D7_0212800" ] }, "reaction_10692562": { "compartment": "compartment_876", "id": "reaction_10692562", "reactome": "R-PFA-561072", "name": "OCT3 mediates renal uptake of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549255" ], "products": [ "species_549326" ], "modifiers": [ [ "species_10692535", "catalyst" ] ], "additional_components": [ "CHEBI:47781", "CHEBI:8428", "CHEBI:42820", "CHEBI:47499", "CHEBI:641", "CHEBI:46020", "CHEBI:46631", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:47499", "CHEBI:47781", "CHEBI:641", "CHEBI:46631", "PF3D7_1203400" ] }, "reaction_10692533": { "compartment": "compartment_876", "id": "reaction_10692533", "reactome": "R-PFA-549297", "name": "SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164988", "species_74113" ], "products": [ "species_30235", "species_83910" ], "modifiers": [ [ "species_10692530", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10692516": { "compartment": "compartment_876", "id": "reaction_10692516", "reactome": "R-PFA-549129", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549264" ], "products": [ "species_549250" ], "modifiers": [ [ "species_10692513", "catalyst" ] ], "additional_components": [ "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "CHEBI:18295", "species_353560", "species_6798162", "CHEBI:16797", "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "CHEBI:16797", "species_6798162", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "CHEBI:18295", "species_353560", "species_209789", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692538": { "compartment": "compartment_876", "id": "reaction_10692538", "reactome": "R-PFA-549304", "name": "OCT3 mediates renal clearance of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549326" ], "products": [ "species_549255" ], "modifiers": [ [ "species_10692535", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:47499", "CHEBI:47781", "CHEBI:641", "CHEBI:46631", "CHEBI:47781", "CHEBI:8428", "CHEBI:42820", "CHEBI:47499", "CHEBI:641", "CHEBI:46020", "CHEBI:46631", "PF3D7_1203400" ] }, "reaction_10692553": { "compartment": "compartment_876", "id": "reaction_10692553", "reactome": "R-PFA-561054", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549266" ], "products": [ "species_549237" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "CHEBI:16797", "CHEBI:16737", "species_6798162", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "CHEBI:18295", "CHEBI:31941", "species_209789", "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "CHEBI:18295", "species_6798162", "CHEBI:16797", "species_209914", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692521": { "compartment": "compartment_876", "id": "reaction_10692521", "reactome": "R-PFA-549241", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549261", "species_74113" ], "products": [ "species_83910", "species_549260" ], "modifiers": [ [ "species_10692518", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10692575": { "compartment": "compartment_876", "id": "reaction_10692575", "reactome": "R-PFA-597628", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_597604", "species_70106" ], "products": [ "species_351626", "species_597623" ], "modifiers": [ [ "species_10692572", "catalyst" ] ], "additional_components": [ "PF3D7_0516500" ] }, "reaction_10692540": { "compartment": "compartment_876", "id": "reaction_10692540", "reactome": "R-PFA-549322", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549250" ], "products": [ "species_549264" ], "modifiers": [ [ "species_10692513", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "CHEBI:16797", "species_6798162", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "CHEBI:18295", "species_353560", "species_209789", "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "CHEBI:18295", "species_353560", "species_6798162", "CHEBI:16797", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692524": { "compartment": "compartment_876", "id": "reaction_10692524", "reactome": "R-PFA-549279", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549237" ], "products": [ "species_549266" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "CHEBI:18295", "species_6798162", "CHEBI:16797", "species_209914", "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "CHEBI:16797", "CHEBI:16737", "species_6798162", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "CHEBI:18295", "CHEBI:31941", "species_209789", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692560": { "compartment": "compartment_876", "id": "reaction_10692560", "reactome": "R-PFA-561059", "name": "OAT2 and OAT4 mediate transport of sulphate conjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561071" ], "products": [ "species_561062", "species_561075" ], "modifiers": [ [ "species_10692557", "catalyst" ] ], "additional_components": [ "CHEBI:16814", "CHEBI:17474", "CHEBI:17474", "CHEBI:16814", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692551": { "compartment": "compartment_876", "id": "reaction_10692551", "reactome": "R-PFA-561041", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561049" ], "products": [ "species_561078", "species_561075" ], "modifiers": [ [ "species_10692548", "catalyst" ] ], "additional_components": [ "CHEBI:104011", "CHEBI:2453", "CHEBI:2453", "CHEBI:104011", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692567": { "compartment": "compartment_876", "id": "reaction_10692567", "reactome": "R-PFA-561253", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_429056" ], "products": [ "species_373863", "species_30034" ], "modifiers": [ [ "species_10692564", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10691904": { "compartment": "compartment_876", "id": "reaction_10691904", "reactome": "R-PFA-443997", "name": "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935", "species_74113" ], "products": [ "species_209789", "species_83910" ], "modifiers": [ [ "species_10691901", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691015": { "compartment": "compartment_876", "id": "reaction_10691015", "reactome": "R-PFA-351963", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266029" ], "products": [ "species_29424" ], "modifiers": [ [ "species_10691012", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691076": { "compartment": "compartment_984", "id": "reaction_10691076", "reactome": "R-PFA-379393", "name": "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_74113" ], "products": [ "species_83910", "species_159362" ], "modifiers": [ [ "species_10691017", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691913": { "compartment": "compartment_70101", "id": "reaction_10691913", "reactome": "R-PFA-444007", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352003", "species_74113" ], "products": [ "species_352011", "species_83910", "species_352022" ], "modifiers": [ [ "species_10691910", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10691023": { "compartment": "compartment_876", "id": "reaction_10691023", "reactome": "R-PFA-352029", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352007", "species_74113" ], "products": [ "species_351982", "species_83910", "species_352022" ], "modifiers": [ [ "species_10690400", "catalyst" ] ], "additional_components": [ "CHEBI:16958", "species_352011", "CHEBI:17750", "CHEBI:48950", "CHEBI:48950", "CHEBI:16958", "CHEBI:17750", "species_352011", "PF3D7_0209600" ] }, "reaction_10691020": { "compartment": "compartment_876", "id": "reaction_10691020", "reactome": "R-PFA-351987", "name": "SLC6A6-mediated uptake of taurine and beta-alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352024", "species_74113" ], "products": [ "species_83910", "species_352019", "species_352022" ], "modifiers": [ [ "species_10691017", "catalyst" ] ], "additional_components": [ "CHEBI:16958", "CHEBI:15891", "CHEBI:16958", "CHEBI:15891", "PF3D7_0209600" ] }, "reaction_10691058": { "compartment": "compartment_876", "id": "reaction_10691058", "reactome": "R-PFA-375473", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375458", "species_74113" ], "products": [ "species_375481", "species_83910" ], "modifiers": [ [ "species_10691055", "catalyst" ] ], "additional_components": [ "species_29432", "CHEBI:57912", "species_29472", "CHEBI:58045", "species_111707", "species_200736", "species_29424", "CHEBI:57427", "species_379705", "CHEBI:58315", "species_29502", "CHEBI:57762", "species_29424", "species_29472", "CHEBI:58315", "species_200736", "CHEBI:57427", "species_379705", "CHEBI:58045", "CHEBI:57762", "species_29432", "species_111707", "CHEBI:57912", "species_29502", "PF3D7_0209600" ] }, "reaction_10691921": { "compartment": "compartment_876", "id": "reaction_10691921", "reactome": "R-PFA-444100", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538", "species_352022" ], "modifiers": [ [ "species_10690402", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691063": { "compartment": "compartment_876", "id": "reaction_10691063", "reactome": "R-PFA-375487", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_375468", "species_74113" ], "products": [ "species_83910", "species_375459", "species_352022" ], "modifiers": [ [ "species_10691060", "catalyst" ] ], "additional_components": [ "species_29432", "CHEBI:57912", "CHEBI:58045", "CHEBI:32513", "species_200736", "species_29424", "species_29468", "CHEBI:16958", "species_1131871", "species_111707", "CHEBI:57427", "species_379705", "CHEBI:57762", "species_200736", "CHEBI:57762", "CHEBI:32513", "species_1131871", "species_29424", "CHEBI:57427", "species_379705", "CHEBI:58045", "CHEBI:16958", "species_29432", "species_111707", "species_29468", "CHEBI:57912", "PF3D7_0209600" ] }, "reaction_10691028": { "compartment": "compartment_876", "id": "reaction_10691028", "reactome": "R-PFA-352052", "name": "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538" ], "modifiers": [ [ "species_10691025", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691930": { "compartment": "compartment_876", "id": "reaction_10691930", "reactome": "R-PFA-444120", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_266029", "species_74113" ], "products": [ "species_83910", "species_352022", "species_29424" ], "modifiers": [ [ "species_10691927", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10691033": { "compartment": "compartment_876", "id": "reaction_10691033", "reactome": "R-PFA-352059", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352051", "species_74113" ], "products": [ "species_83910", "species_352048" ], "modifiers": [ [ "species_10691030", "catalyst" ] ], "additional_components": [ "species_29432", "species_29472", "CHEBI:58045", "species_379717", "CHEBI:57926", "species_111707", "species_200736", "species_29642", "CHEBI:57427", "species_379705", "CHEBI:18240", "CHEBI:57762", "species_29472", "species_379717", "CHEBI:57926", "species_200736", "CHEBI:57427", "species_379705", "CHEBI:18240", "CHEBI:58045", "CHEBI:57762", "species_29432", "species_29642", "species_111707", "PF3D7_0209600" ] }, "reaction_10691948": { "compartment": "compartment_984", "id": "reaction_10691948", "reactome": "R-PFA-444433", "name": "Cho transports from the extracellular space to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264638" ], "products": [ "species_264618" ], "modifiers": [ [ "species_10691945", "catalyst" ] ], "additional_components": [ "Q8ILE6", "PF3D7_1431900" ] }, "reaction_10702179": { "compartment": "compartment_70101", "id": "reaction_10702179", "reactome": "R-PFA-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_2162265", "species_71285" ], "modifiers": [ [ "species_10702176", "catalyst" ] ], "additional_components": [ "PF3D7_1241600" ] }, "reaction_10691543": { "compartment": "compartment_876", "id": "reaction_10691543", "reactome": "R-PFA-427605", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10691540", "catalyst" ] ], "additional_components": [ "Q8IDS7", "PF3D7_1340900" ] }, "reaction_10692626": { "compartment": "compartment_20699", "id": "reaction_10692626", "reactome": "R-PFA-742345", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742368" ], "products": [ "species_205683" ], "modifiers": [ [ "species_10692623", "catalyst" ] ], "additional_components": [ "PF3D7_0212000" ] }, "reaction_10692613": { "compartment": "compartment_20699", "id": "reaction_10692613", "reactome": "R-PFA-727807", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727810", "species_4085435" ], "products": [ "species_727815", "species_109395" ], "modifiers": [ [ "species_10692610", "catalyst" ] ], "additional_components": [ "PF3D7_0505300" ] }, "reaction_10692618": { "compartment": "compartment_20699", "id": "reaction_10692618", "reactome": "R-PFA-735702", "name": "SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735698", "species_735692" ], "products": [ "species_109402", "species_735691" ], "modifiers": [ [ "species_10692615", "catalyst" ] ], "additional_components": [ "species_735700", "species_735682", "species_735682", "species_735700", "PF3D7_0505300" ] }, "reaction_10688817": { "compartment": "compartment_70101", "id": "reaction_10688817", "reactome": "R-PFA-109536", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737" ], "products": [ "species_179743" ], "modifiers": [ [ "species_10688812", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:16335", "CHEBI:17562", "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692593": { "compartment": "compartment_70101", "id": "reaction_10692593", "reactome": "R-PFA-727749", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727782" ], "products": [ "species_727746" ], "modifiers": [ [ "species_10692590", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17596", "CHEBI:16704", "CHEBI:16750", "CHEBI:17562", "CHEBI:17748", "species_5635947", "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "species_5635947", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10689584": { "compartment": "compartment_70616", "id": "reaction_10689584", "reactome": "R-PFA-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10689581", "catalyst" ] ], "additional_components": [ "Q8IJ34", "PF3D7_1037300", "Q8IBF2", "PF3D7_1037300" ] }, "reaction_10688810": { "compartment": "compartment_70101", "id": "reaction_10688810", "reactome": "R-PFA-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10688805", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:16040", "CHEBI:16235", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17821", "species_83962", "CHEBI:17562", "species_5635947", "species_29850", "CHEBI:17596", "CHEBI:16750", "CHEBI:16235", "CHEBI:16704", "CHEBI:17748", "species_29850", "CHEBI:16335", "CHEBI:17821", "species_83962", "species_5635947", "CHEBI:17562", "CHEBI:16040", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10688808": { "compartment": "compartment_70101", "id": "reaction_10688808", "reactome": "R-PFA-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10688805", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16235", "CHEBI:16704", "CHEBI:17748", "species_29850", "CHEBI:16335", "CHEBI:17821", "species_83962", "species_5635947", "CHEBI:17562", "CHEBI:16040", "CHEBI:16335", "CHEBI:16040", "CHEBI:16235", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17821", "species_83962", "CHEBI:17562", "species_5635947", "species_29850", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10692584": { "compartment": "compartment_70101", "id": "reaction_10692584", "reactome": "R-PFA-727740", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727774" ], "products": [ "species_727737" ], "modifiers": [ [ "species_10692581", "catalyst" ] ], "additional_components": [ "species_209789", "CHEBI:16335", "species_209914", "species_380873", "CHEBI:28918", "species_380873", "CHEBI:28918", "CHEBI:16335", "species_209914", "species_209789", "Q8IKE3", "PF3D7_1469400", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10688815": { "compartment": "compartment_70101", "id": "reaction_10688815", "reactome": "R-PFA-109534", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179743" ], "products": [ "species_179737" ], "modifiers": [ [ "species_10688812", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:16335", "CHEBI:17562", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692605": { "compartment": "compartment_70101", "id": "reaction_10692605", "reactome": "R-PFA-727768", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727737" ], "products": [ "species_727774" ], "modifiers": [ [ "species_10692581", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:16335", "species_209914", "species_209789", "species_209789", "CHEBI:16335", "species_209914", "species_380873", "CHEBI:28918", "Q8IKE3", "PF3D7_1469400", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692601": { "compartment": "compartment_20699", "id": "reaction_10692601", "reactome": "R-PFA-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10692598", "catalyst" ] ], "additional_components": [ "PF3D7_1036800" ] }, "reaction_10703281": { "compartment": "compartment_70101", "id": "reaction_10703281", "reactome": "R-PFA-8981574", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10691617": { "compartment": "compartment_876", "id": "reaction_10691617", "reactome": "R-PFA-428779", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428819" ], "products": [ "species_428802" ], "modifiers": [ [ "species_10691614", "catalyst" ] ], "additional_components": [ "species_70115", "species_29532", "species_70115", "species_29532", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692151": { "compartment": "compartment_70101", "id": "reaction_10692151", "reactome": "R-PFA-450092", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692147" ], "products": [ "species_113592", "species_10692145" ], "modifiers": [], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "species_29358", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10696565": { "compartment": "compartment_70101", "id": "reaction_10696565", "reactome": "R-PFA-5339524", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10692145", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692149": { "compartment": "compartment_70101", "id": "reaction_10692149", "reactome": "R-PFA-450088", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10692145" ], "products": [ "species_10692147" ], "modifiers": [], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "species_29358" ] }, "reaction_10703268": { "compartment": "compartment_70101", "id": "reaction_10703268", "reactome": "R-PFA-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703265", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692154": { "compartment": "compartment_70101", "id": "reaction_10692154", "reactome": "R-PFA-450095", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10691626": { "compartment": "compartment_876", "id": "reaction_10691626", "reactome": "R-PFA-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10691623", "catalyst" ] ], "additional_components": [ "species_70115", "species_30034", "species_29532", "species_70115", "species_30034", "species_29532", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10703279": { "compartment": "compartment_70101", "id": "reaction_10703279", "reactome": "R-PFA-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703276", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10703263": { "compartment": "compartment_70101", "id": "reaction_10703263", "reactome": "R-PFA-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703260", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10698311": { "compartment": "compartment_70101", "id": "reaction_10698311", "reactome": "R-PFA-5690873", "name": "ACO1 binds 4Fe-4S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690881", "species_10698307" ], "products": [ "species_10698309" ], "modifiers": [], "additional_components": [ "PF3D7_1342100", "Q8IDR8", "PF3D7_1342100" ] }, "reaction_10692748": { "compartment": "compartment_74700", "id": "reaction_10692748", "reactome": "R-PFA-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_70106", "species_113592" ], "products": [ "species_29372", "species_29370", "species_74722" ], "modifiers": [ [ "species_10688527", "catalyst" ] ], "additional_components": [ "C0H4P0", "PF3D7_0721900", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8IDF7", "PF3D7_1354400", "Q8IKJ0", "PF3D7_1464700", "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10698318": { "compartment": "compartment_70101", "id": "reaction_10698318", "reactome": "R-PFA-5690911", "name": "ACO1:4Fe-4S isomerises CIT to ISCIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76190" ], "products": [ "species_389545" ], "modifiers": [ [ "species_10698309", "catalyst" ] ], "additional_components": [ "Q8IDR8", "PF3D7_1342100" ] }, "reaction_10698349": { "compartment": "compartment_70101", "id": "reaction_10698349", "reactome": "R-PFA-5691108", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698313", "species_10686740" ], "products": [ "species_10698340" ], "modifiers": [ [ "species_10698346", "catalyst" ] ], "additional_components": [ "PF3D7_1342100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1342100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "Q8IEI4", "PF3D7_1313000" ] }, "reaction_10692878": { "compartment": "compartment_70101", "id": "reaction_10692878", "reactome": "R-PFA-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10692873" ], "products": [ "species_10692875", "species_29370" ], "modifiers": [ [ "species_10692873", "catalyst" ] ], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500" ] }, "reaction_10697478": { "compartment": "compartment_7660", "id": "reaction_10697478", "reactome": "R-PFA-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697474" ], "products": [ "species_10697476" ], "modifiers": [], "additional_components": [ "PF3D7_1423600", "Q8ILL6", "PF3D7_1423600" ] }, "reaction_10697486": { "compartment": "compartment_7660", "id": "reaction_10697486", "reactome": "R-PFA-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10697476" ], "products": [ "species_113582", "species_10697483" ], "modifiers": [ [ "species_10697476", "catalyst" ] ], "additional_components": [ "Q8ILL6", "PF3D7_1423600", "PF3D7_1423600", "Q8ILL6", "PF3D7_1423600" ] }, "reaction_10689771": { "compartment": "compartment_70101", "id": "reaction_10689771", "reactome": "R-PFA-174159", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10689766" ], "products": [ "species_10689768" ], "modifiers": [ [ "species_10689762", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000" ] }, "reaction_10689773": { "compartment": "compartment_70101", "id": "reaction_10689773", "reactome": "R-PFA-174203", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689768" ], "products": [ "species_10686740", "species_10689729", "species_10689762" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1026400", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10686942": { "compartment": "compartment_7660", "id": "reaction_10686942", "reactome": "R-PFA-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_10686458", "species_30185", "species_29892", "species_29604" ], "products": [ "species_10686939" ], "modifiers": [ [ "species_10686433", "catalyst" ] ], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10686461": { "compartment": "compartment_7660", "id": "reaction_10686461", "reactome": "R-PFA-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686456", "species_30595" ], "products": [ "species_10686458", "species_10686452" ], "modifiers": [ [ "species_10686456", "catalyst" ] ], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10688544": { "compartment": "compartment_13231", "id": "reaction_10688544", "reactome": "R-PFA-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688540" ], "products": [ "species_10688542" ], "modifiers": [], "additional_components": [ "PF3D7_0704700", "PF3D7_0704700" ] }, "reaction_10688548": { "compartment": "compartment_70101", "id": "reaction_10688548", "reactome": "R-PFA-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688546" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IC23", "PF3D7_0704700", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10689779": { "compartment": "compartment_13231", "id": "reaction_10689779", "reactome": "R-PFA-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689722" ], "products": [ "species_10689741" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900" ] }, "reaction_10689952": { "compartment": "compartment_7660", "id": "reaction_10689952", "reactome": "R-PFA-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10689775" ], "products": [ "species_113582", "species_10689777" ], "modifiers": [ [ "species_10686575", "catalyst" ] ], "additional_components": [ "PF3D7_1026400", "PF3D7_1026400", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10689724": { "compartment": "compartment_70101", "id": "reaction_10689724", "reactome": "R-PFA-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687085", "species_10689716" ], "products": [ "species_10689722" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10696324": { "compartment": "compartment_13231", "id": "reaction_10696324", "reactome": "R-PFA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10695746", "catalyst" ] ], "additional_components": [ "O77317", "PF3D7_0303200" ] }, "reaction_10694673": { "compartment": "compartment_7660", "id": "reaction_10694673", "reactome": "R-PFA-2288097", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694648", "species_10694615" ], "products": [ "species_10694667" ], "modifiers": [ [ "species_10694671", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600" ] }, "reaction_10694709": { "compartment": "compartment_7660", "id": "reaction_10694709", "reactome": "R-PFA-2301205", "name": "SETD8 monomethylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694658" ], "products": [ "species_77502", "species_10694654" ], "modifiers": [ [ "species_10694706", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067", "PF3D7_0403900" ] }, "reaction_10694661": { "compartment": "compartment_7660", "id": "reaction_10694661", "reactome": "R-PFA-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694654", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10694658" ], "modifiers": [ [ "species_10694654", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067" ] }, "reaction_10694699": { "compartment": "compartment_7660", "id": "reaction_10694699", "reactome": "R-PFA-2294580", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10694683" ], "products": [ "species_113582", "species_10694696" ], "modifiers": [ [ "species_10694683", "catalyst" ] ], "additional_components": [ "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000" ] }, "reaction_10694841": { "compartment": "compartment_70101", "id": "reaction_10694841", "reactome": "R-PFA-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10694807" ], "products": [ "species_10694797", "species_29370" ], "modifiers": [ [ "species_10694838", "catalyst" ] ], "additional_components": [ "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8I413", "PF3D7_0509100", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I413", "PF3D7_0509100", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200", "Q8IDR5", "PF3D7_1342400" ] }, "reaction_10694809": { "compartment": "compartment_70101", "id": "reaction_10694809", "reactome": "R-PFA-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694797", "species_29356" ], "products": [ "species_29372", "species_10694807" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I413", "PF3D7_0509100", "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8I413", "PF3D7_0509100", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100" ] }, "reaction_10689490": { "compartment": "compartment_13231", "id": "reaction_10689490", "reactome": "R-PFA-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687093" ], "products": [ "species_10687099" ], "modifiers": [], "additional_components": [ "Q8IC23", "PF3D7_0704700", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900" ] }, "reaction_10687095": { "compartment": "compartment_70101", "id": "reaction_10687095", "reactome": "R-PFA-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687085", "species_10687091" ], "products": [ "species_10687093" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IC23", "PF3D7_0704700", "Q8IC23", "PF3D7_0704700", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10689368": { "compartment": "compartment_7660", "id": "reaction_10689368", "reactome": "R-PFA-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686939" ], "products": [ "species_113656", "species_10686433" ], "modifiers": [], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10686946": { "compartment": "compartment_7660", "id": "reaction_10686946", "reactome": "R-PFA-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686452", "species_68419" ], "products": [ "species_10686454" ], "modifiers": [], "additional_components": [ "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10686463": { "compartment": "compartment_7660", "id": "reaction_10686463", "reactome": "R-PFA-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686454", "species_10686433" ], "products": [ "species_10686456" ], "modifiers": [], "additional_components": [ "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10702067": { "compartment": "compartment_70101", "id": "reaction_10702067", "reactome": "R-PFA-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702063", "species_10702058" ], "products": [ "species_10702065" ], "modifiers": [], "additional_components": [ "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200" ] }, "reaction_10702090": { "compartment": "compartment_70101", "id": "reaction_10702090", "reactome": "R-PFA-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10702065" ], "products": [ "species_10702087" ], "modifiers": [ [ "species_10702065", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200", "O77328", "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200" ] }, "reaction_10702092": { "compartment": "compartment_70101", "id": "reaction_10702092", "reactome": "R-PFA-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702087" ], "products": [ "species_10702058", "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "O77328", "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10690786": { "compartment": "compartment_70101", "id": "reaction_10690786", "reactome": "R-PFA-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10690778" ], "products": [ "species_29420", "species_10690709" ], "modifiers": [ [ "species_10690783", "catalyst" ] ], "additional_components": [ "Q8I1S0", "PF3D7_0416800", "species_29420", "Q8I1S0", "PF3D7_0416800", "species_29438", "PF3D7_1116400" ] }, "reaction_10698657": { "compartment": "compartment_12045", "id": "reaction_10698657", "reactome": "R-PFA-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690764", "species_10690794", "species_10690709" ], "products": [ "species_10690766" ], "modifiers": [], "additional_components": [ "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29438", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698560": { "compartment": "compartment_13959", "id": "reaction_10698560", "reactome": "R-PFA-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10698553" ], "products": [ "species_10698557", "species_29420" ], "modifiers": [ [ "species_10698553", "catalyst" ] ], "additional_components": [ "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100" ] }, "reaction_10701589": { "compartment": "compartment_6791047", "id": "reaction_10701589", "reactome": "R-PFA-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701211", "species_10701585" ], "products": [ "species_10701587" ], "modifiers": [], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "PF3D7_0323100", "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438" ] }, "reaction_10698660": { "compartment": "compartment_70101", "id": "reaction_10698660", "reactome": "R-PFA-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690766" ], "products": [ "species_10690764", "species_29372", "species_10690794", "species_10690778" ], "modifiers": [ [ "species_10690766", "catalyst" ] ], "additional_components": [ "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29420", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698616": { "compartment": "compartment_6791047", "id": "reaction_10698616", "reactome": "R-PFA-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10698612" ], "products": [ "species_10698614" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "O97323", "PF3D7_0320100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IJ69", "PF3D7_1034000", "O97323", "PF3D7_0320100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IJ69", "PF3D7_1034000", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701592": { "compartment": "compartment_6791047", "id": "reaction_10701592", "reactome": "R-PFA-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701587" ], "products": [ "species_10698448", "species_10701585" ], "modifiers": [ [ "species_10701587", "catalyst" ] ], "additional_components": [ "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "PF3D7_0323100", "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438" ] }, "reaction_10698620": { "compartment": "compartment_13959", "id": "reaction_10698620", "reactome": "R-PFA-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698508", "species_10698551", "species_10698448" ], "products": [ "species_10698553" ], "modifiers": [], "additional_components": [ "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100" ] }, "reaction_10694722": { "compartment": "compartment_5460", "id": "reaction_10694722", "reactome": "R-PFA-2395512", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694718", "species_10693606" ], "products": [ "species_10693598", "species_113529", "species_10694720" ], "modifiers": [], "additional_components": [ "species_31649", "Q8IHW9", "PF3D7_1139700", "Q8I5R0", "PF3D7_1214600", "CHEBI:33737", "CHEBI:33738", "Q8I5R0", "PF3D7_1214600", "species_29386", "Q8IHW9", "PF3D7_1139700" ] }, "reaction_10694724": { "compartment": "compartment_5460", "id": "reaction_10694724", "reactome": "R-PFA-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_10694720", "species_113600" ], "products": [ "species_10694718", "species_113563" ], "modifiers": [], "additional_components": [ "species_29386", "Q8IHW9", "PF3D7_1139700", "species_31649", "Q8IHW9", "PF3D7_1139700" ] }, "reaction_10695704": { "compartment": "compartment_7660", "id": "reaction_10695704", "reactome": "R-PFA-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10694930" ], "products": [ "species_10695702", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695676": { "compartment": "compartment_7660", "id": "reaction_10695676", "reactome": "R-PFA-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695666" ], "products": [ "species_10695674", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1360700", "Q8I444", "PF3D7_0505800", "A0A5K1K9G1", "PF3D7_1360700", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10703252": { "compartment": "compartment_984", "id": "reaction_10703252", "reactome": "R-PFA-8979996", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10703249", "catalyst" ] ], "additional_components": [] }, "reaction_10688609": { "compartment": "compartment_70101", "id": "reaction_10688609", "reactome": "R-PFA-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_75970", "species_73473" ], "products": [ "species_76114", "species_29360" ], "modifiers": [ [ "species_10688606", "catalyst" ] ], "additional_components": [ "Q8IIL4", "PF3D7_1114800", "Q8I5P5", "PF3D7_1216200" ] }, "reaction_10702964": { "compartment": "compartment_5460", "id": "reaction_10702964", "reactome": "R-PFA-8878654", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878649", "species_113521" ], "products": [ "species_113548", "species_8934414" ], "modifiers": [ [ "species_10702961", "catalyst" ] ], "additional_components": [ "PF3D7_0208400" ] }, "reaction_10688574": { "compartment": "compartment_12045", "id": "reaction_10688574", "reactome": "R-PFA-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_426755", "species_76194" ], "modifiers": [ [ "species_10688571", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700", "Q8IL28", "PF3D7_1444300" ] }, "reaction_10699324": { "compartment": "compartment_70101", "id": "reaction_10699324", "reactome": "R-PFA-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10699321", "catalyst" ] ], "additional_components": [ "Q8IAY0", "PF3D7_0814400" ] }, "reaction_10692323": { "compartment": "compartment_876", "id": "reaction_10692323", "reactome": "R-PFA-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692305" ], "products": [ "species_10692321" ], "modifiers": [], "additional_components": [ "Q8IBM9", "PF3D7_0722400", "Q7KQL9", "PF14_0425", "Q8I509", "PF3D7_1242000", "Q8I563", "PF3D7_1448600", "Q8IKY7", "PF3D7_1448600", "O96268", "PF3D7_0219100", "Q7KQL9", "PF14_0425", "Q8IBM9", "PF3D7_0722400", "Q8I509", "PF3D7_1242000", "O96268", "PF3D7_0219100", "Q8IKY7", "PF3D7_1448600", "Q8I563", "PF3D7_1448600" ] }, "reaction_10692394": { "compartment": "compartment_70101", "id": "reaction_10692394", "reactome": "R-PFA-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692370" ], "products": [ "species_10692392" ], "modifiers": [], "additional_components": [ "Q8I2G8", "PF3D7_0935200", "C6KSX9", "PF3D7_0935200", "Q8IFP3", "PF3D7_0903700", "Q6ZLZ9", "PF3D7_0903700", "Q8ILW9", "PF3D7_1246200", "Q8I4X0", "PF3D7_1246200", "P62203", "PF14_0323", "Q8ILW9", "PF3D7_1246200", "Q8I4X0", "PF3D7_1246200", "C6KSX9", "PF3D7_0935200", "Q8I2G8", "PF3D7_0935200", "P62203", "PF14_0323", "Q8IFP3", "PF3D7_0903700", "Q6ZLZ9", "PF3D7_0903700" ] }, "reaction_10692329": { "compartment": "compartment_876", "id": "reaction_10692329", "reactome": "R-PFA-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692325" ], "products": [ "species_10692327" ], "modifiers": [], "additional_components": [ "PF3D7_1367500", "PF3D7_1367500" ] }, "reaction_10688412": { "compartment": "compartment_70101", "id": "reaction_10688412", "reactome": "R-PFA-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500430" ], "products": [ "species_83962", "species_500244" ], "modifiers": [ [ "species_10688407", "catalyst" ] ], "additional_components": [ "CHEBI:16450", "CHEBI:16704", "CHEBI:28542", "species_112016", "Q8I3X4", "PF3D7_0513300" ] }, "reaction_10703354": { "compartment": "compartment_70101", "id": "reaction_10703354", "reactome": "R-PFA-9018895", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023653", "species_29450" ], "products": [ "species_29356", "species_9023651", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10703352": { "compartment": "compartment_70101", "id": "reaction_10703352", "reactome": "R-PFA-9018868", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9020583", "species_29450" ], "products": [ "species_29356", "species_9020474", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10692893": { "compartment": "compartment_70101", "id": "reaction_10692893", "reactome": "R-PFA-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692886" ], "products": [ "species_10692888", "species_10686740" ], "modifiers": [ [ "species_10692890", "catalyst" ] ], "additional_components": [ "PF3D7_1439100", "PF3D7_1439100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PFC1020c" ] }, "reaction_10691191": { "compartment": "compartment_876", "id": "reaction_10691191", "reactome": "R-PFA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691189" ], "products": [ "species_10691189" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "Q8IKI3", "PF3D7_1465500", "Q8I5E6", "PF3D7_1465500", "Q8IKI3", "PF3D7_1465500", "Q8I5E6", "PF3D7_1465500", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10692412": { "compartment": "compartment_876", "id": "reaction_10692412", "reactome": "R-PFA-499981", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10692409", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10687135": { "compartment": "compartment_70101", "id": "reaction_10687135", "reactome": "R-PFA-70342", "name": "ALDOB tetramer cleaves Fru-1-P to GA and DHAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31221" ], "products": [ "species_30393", "species_75970" ], "modifiers": [ [ "species_10687132", "catalyst" ] ], "additional_components": [ "Q7KQL9", "PF14_0425" ] }, "reaction_10702809": { "compartment": "compartment_70101", "id": "reaction_10702809", "reactome": "R-PFA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10702806", "catalyst" ] ], "additional_components": [ "PF3D7_0309300" ] }, "reaction_10687203": { "compartment": "compartment_70101", "id": "reaction_10687203", "reactome": "R-PFA-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10687198", "catalyst" ] ], "additional_components": [ "Q8ILA4", "PF3D7_1436000" ] }, "reaction_10687522": { "compartment": "compartment_5460", "id": "reaction_10687522", "reactome": "R-PFA-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_29362", "species_113587" ], "products": [ "species_113544", "species_113526" ], "modifiers": [ [ "species_10687371", "catalyst" ] ], "additional_components": [ "Q76NM3", "PF3D7_1324900" ] }, "reaction_10687239": { "compartment": "compartment_70101", "id": "reaction_10687239", "reactome": "R-PFA-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29492" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10687236", "catalyst" ] ], "additional_components": [ "Q8IJN7", "PF10_0155", "species_29926" ] }, "reaction_10687223": { "compartment": "compartment_70101", "id": "reaction_10687223", "reactome": "R-PFA-70486", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29728" ], "products": [ "species_29370", "species_29800" ], "modifiers": [ [ "species_10687220", "catalyst" ] ], "additional_components": [ "species_29926", "P27362", "PFI1105w" ] }, "reaction_10687207": { "compartment": "compartment_70101", "id": "reaction_10687207", "reactome": "R-PFA-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29800", "species_73473" ], "products": [ "species_29372", "species_29578", "species_29360" ], "modifiers": [ [ "species_10687178", "catalyst" ] ], "additional_components": [ "Q8IKK7", "PF3D7_1462800" ] }, "reaction_10687447": { "compartment": "compartment_70101", "id": "reaction_10687447", "reactome": "R-PFA-71495", "name": "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578", "species_75970" ], "products": [ "species_30014" ], "modifiers": [ [ "species_10687132", "catalyst" ] ], "additional_components": [ "Q7KQL9", "PF14_0425" ] }, "reaction_10687205": { "compartment": "compartment_70101", "id": "reaction_10687205", "reactome": "R-PFA-70481", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578" ], "products": [ "species_75970" ], "modifiers": [ [ "species_10687188", "catalyst" ] ], "additional_components": [ "Q7KQM0", "PF14_0378" ] }, "reaction_10687444": { "compartment": "compartment_70101", "id": "reaction_10687444", "reactome": "R-PFA-71445", "name": "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30485" ], "products": [ "species_29728" ], "modifiers": [ [ "species_10687441", "catalyst" ] ], "additional_components": [ "Q8IIG6", "PF3D7_1120100" ] }, "reaction_10687272": { "compartment": "compartment_5460", "id": "reaction_10687272", "reactome": "R-PFA-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_113552" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10689720": { "compartment": "compartment_13231", "id": "reaction_10689720", "reactome": "R-PFA-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689718" ], "products": [ "species_10687154" ], "modifiers": [], "additional_components": [ "PF3D7_0624000", "PF3D7_0624000" ] }, "reaction_10687163": { "compartment": "compartment_70101", "id": "reaction_10687163", "reactome": "R-PFA-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10687160", "catalyst" ] ], "additional_components": [ "C6KT76", "PF3D7_0624000" ] }, "reaction_10687480": { "compartment": "compartment_70101", "id": "reaction_10687480", "reactome": "R-PFA-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10687477", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_29358", "inhibitor" ], [ "species_30389", "inhibitor" ] ], "additional_components": [ "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "species_29926", "species_74126" ] }, "reaction_10703214": { "compartment": "compartment_70101", "id": "reaction_10703214", "reactome": "R-PFA-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29800" ], "products": [ "species_70106", "species_8955759", "species_29728" ], "modifiers": [ [ "species_10687120", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10699884": { "compartment": "compartment_70101", "id": "reaction_10699884", "reactome": "R-PFA-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10699881", "catalyst" ] ], "additional_components": [ "Q8IIG6", "PF3D7_1120100" ] }, "reaction_10688330": { "compartment": "compartment_70101", "id": "reaction_10688330", "reactome": "R-PFA-73646", "name": "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688318", "species_70106", "species_29364" ], "products": [ "species_29366", "species_10688320" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "P61076", "PFI1170c", "species_29386" ] }, "reaction_10687149": { "compartment": "compartment_70101", "id": "reaction_10687149", "reactome": "R-PFA-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29366" ], "products": [ "species_70106", "species_31467", "species_29364" ], "modifiers": [ [ "species_10687146", "catalyst" ] ], "additional_components": [ "species_29366", "Q8IKU0", "PF14_0511" ] }, "reaction_10703102": { "compartment": "compartment_876", "id": "reaction_10703102", "reactome": "R-PFA-8943987", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703094" ], "products": [ "species_10703100" ], "modifiers": [], "additional_components": [ "C0H518", "PF3D7_1208200", "A0A5K1K8N7", "PF3D7_1208200", "C0H518", "PF3D7_1208200", "A0A5K1K8N7", "PF3D7_1208200" ] }, "reaction_10698562": { "compartment": "compartment_12045", "id": "reaction_10698562", "reactome": "R-PFA-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690729", "species_10690727", "species_10690721" ], "products": [ "species_10690731" ], "modifiers": [], "additional_components": [ "PF3D7_0822600", "C0H489", "PF3D7_0405100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10698618": { "compartment": "compartment_12045", "id": "reaction_10698618", "reactome": "R-PFA-5694428", "name": "LMAN family proteins bind glycosylated cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690760", "species_10690746" ], "products": [ "species_10690762" ], "modifiers": [], "additional_components": [ "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8I2A1", "PF3D7_0103900", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698568": { "compartment": "compartment_12045", "id": "reaction_10698568", "reactome": "R-PFA-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690729", "species_10690665", "species_10698564" ], "products": [ "species_10698566" ], "modifiers": [], "additional_components": [ "PF3D7_0822600", "PF3D7_0320100", "C0H5J6", "PF3D7_1361100", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10694553": { "compartment": "compartment_70101", "id": "reaction_10694553", "reactome": "R-PFA-2161961", "name": "EET(1) is hydrolysed to DHET(1) by EPHX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2161818" ], "products": [ "species_2161883" ], "modifiers": [ [ "species_10694550", "catalyst" ] ], "additional_components": [ "CHEBI:34450", "CHEBI:34130", "CHEBI:34490", "CHEBI:34157", "CHEBI:63974", "CHEBI:63969", "CHEBI:63970", "CHEBI:63966", "species_29926", "Q8IM75", "PF3D7_1401300" ] }, "reaction_10703339": { "compartment": "compartment_5460", "id": "reaction_10703339", "reactome": "R-PFA-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703402": { "compartment": "compartment_5460", "id": "reaction_10703402", "reactome": "R-PFA-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_10703333" ], "products": [ "species_10703400", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400", "PF3D7_1206400", "PF3D7_1206400" ] }, "reaction_10703336": { "compartment": "compartment_5460", "id": "reaction_10703336", "reactome": "R-PFA-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703343": { "compartment": "compartment_5460", "id": "reaction_10703343", "reactome": "R-PFA-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703341": { "compartment": "compartment_5460", "id": "reaction_10703341", "reactome": "R-PFA-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703132": { "compartment": "compartment_70101", "id": "reaction_10703132", "reactome": "R-PFA-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698288" ], "products": [ "species_10698286", "species_10698177" ], "modifiers": [], "additional_components": [ "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "PF3D7_1313000", "PF3D7_1460400" ] }, "reaction_10692793": { "compartment": "compartment_70101", "id": "reaction_10692793", "reactome": "R-PFA-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692761", "species_10692789" ], "products": [ "species_10692791" ], "modifiers": [], "additional_components": [ "PF3D7_1005500", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IIC9", "PF3D7_1123400", "species_29420", "O96203", "PF3D7_0212300", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IIC9", "PF3D7_1123400", "species_29420", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500" ] }, "reaction_10690540": { "compartment": "compartment_70101", "id": "reaction_10690540", "reactome": "R-PFA-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10690537", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10692468": { "compartment": "compartment_70101", "id": "reaction_10692468", "reactome": "R-PFA-514604", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113578", "species_29364" ], "products": [ "species_29366", "species_29602", "species_31633" ], "modifiers": [ [ "species_10692465", "catalyst" ] ], "additional_components": [ "Q8I2U5", "PF3D7_0920800" ] }, "reaction_10688719": { "compartment": "compartment_70101", "id": "reaction_10688719", "reactome": "R-PFA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10688716", "catalyst" ] ], "additional_components": [ "Q8IE53", "PF3D7_1329400" ] }, "reaction_10688380": { "compartment": "compartment_70101", "id": "reaction_10688380", "reactome": "R-PFA-74215", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_500259" ], "products": [ "species_111294", "species_500260" ], "modifiers": [ [ "species_10688377", "catalyst" ] ], "additional_components": [ "CHEBI:16235", "species_29850", "species_29602", "species_113578", "Q8IJS1", "PF3D7_1012400", "species_29926" ] }, "reaction_10688396": { "compartment": "compartment_70101", "id": "reaction_10688396", "reactome": "R-PFA-74241", "name": "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH4+ (ADA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500173" ], "products": [ "species_500172", "species_31633" ], "modifiers": [ [ "species_10688393", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17256", "CHEBI:28997", "CHEBI:17596", "PF3D7_1029600" ] }, "reaction_10702565": { "compartment": "compartment_70101", "id": "reaction_10702565", "reactome": "R-PFA-8870457", "name": "FarC-PTP4A2 binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702559", "species_10702561" ], "products": [ "species_10702563" ], "modifiers": [], "additional_components": [ "PF3D7_1113100", "PF3D7_0602500", "C6KSM5", "PF3D7_0602500", "Q8IIN1", "PF3D7_1113100" ] }, "reaction_10702571": { "compartment": "compartment_70101", "id": "reaction_10702571", "reactome": "R-PFA-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702567", "species_10702561" ], "products": [ "species_10702569" ], "modifiers": [ [ "species_10702563", "inhibitor" ] ], "additional_components": [ "PF3D7_1442500", "PF3D7_0602500", "C6KSM5", "PF3D7_0602500", "Q8IL46", "PF3D7_1442500", "C6KSM5", "PF3D7_0602500", "Q8IIN1", "PF3D7_1113100" ] }, "reaction_10688826": { "compartment": "compartment_876", "id": "reaction_10688826", "reactome": "R-PFA-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10688822" ], "products": [ "species_10688824" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "Q8IIE7", "PF3D7_1121900", "species_179838" ] }, "reaction_10701191": { "compartment": "compartment_5460", "id": "reaction_10701191", "reactome": "R-PFA-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10701188", "catalyst" ] ], "additional_components": [ "Q8IKN4", "PF14_0570" ] }, "reaction_10690276": { "compartment": "compartment_70101", "id": "reaction_10690276", "reactome": "R-PFA-197186", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197230", "species_70106" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10690273", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "C6KTC6", "PF3D7_0629100" ] }, "reaction_10702553": { "compartment": "compartment_876", "id": "reaction_10702553", "reactome": "R-PFA-8869603", "name": "SLC22A13 transports NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8869604" ], "products": [ "species_197230" ], "modifiers": [ [ "species_10692518", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10701199": { "compartment": "compartment_5460", "id": "reaction_10701199", "reactome": "R-PFA-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6807477" ], "products": [ "species_113548", "species_113581", "species_113529", "species_113600" ], "modifiers": [ [ "species_10701196", "catalyst" ] ], "additional_components": [ "PF3D7_1143900" ] }, "reaction_10703211": { "compartment": "compartment_5460", "id": "reaction_10703211", "reactome": "R-PFA-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113526" ], "products": [ "species_113581", "species_113563", "species_113529" ], "modifiers": [ [ "species_10703208", "catalyst" ] ], "additional_components": [ "Q8I319", "PF3D7_0913300" ] }, "reaction_10690286": { "compartment": "compartment_70101", "id": "reaction_10690286", "reactome": "R-PFA-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_197256", "species_113592", "species_29472" ], "products": [ "species_111294", "species_29404", "species_76577", "species_29360" ], "modifiers": [ [ "species_10690283", "catalyst" ] ], "additional_components": [ "Q8I2P2", "PF3D7_0926700" ] }, "reaction_10690218": { "compartment": "compartment_70101", "id": "reaction_10690218", "reactome": "R-PFA-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196095", "species_70106", "species_29364" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10690215", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10703665": { "compartment": "compartment_70101", "id": "reaction_10703665", "reactome": "R-PFA-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10695751", "catalyst" ] ], "additional_components": [ "PF3D7_1455900" ] }, "reaction_10698686": { "compartment": "compartment_5460", "id": "reaction_10698686", "reactome": "R-PFA-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_5696835" ], "products": [ "species_113529", "species_5696848", "species_113600" ], "modifiers": [ [ "species_10698683", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10696894": { "compartment": "compartment_70101", "id": "reaction_10696894", "reactome": "R-PFA-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696892", "species_29438" ], "products": [ "species_29420", "species_10696890" ], "modifiers": [ [ "species_10690962", "catalyst" ] ], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q7KQL3", "PF10_0203", "species_29438", "PF3D7_1442900" ] }, "reaction_10690946": { "compartment": "compartment_70101", "id": "reaction_10690946", "reactome": "R-PFA-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10690943", "catalyst" ] ], "additional_components": [ "PF3D7_1033100" ] }, "reaction_10686402": { "compartment": "compartment_7660", "id": "reaction_10686402", "reactome": "R-PFA-68611", "name": "Orc1 associates with Orc4:Orc5:Orc3:Orc2:origin complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686398", "species_10686393" ], "products": [ "species_10686400" ], "modifiers": [], "additional_components": [ "PF3D7_1203000", "Q8IC17", "PF3D7_0705300", "O96237", "PF3D7_0215800", "A0A5K1K8V1", "PF3D7_1334100", "Q8IC17", "PF3D7_0705300", "O96237", "PF3D7_0215800", "A0A5K1K8V1", "PF3D7_1334100", "Q8I615", "PF3D7_1203000" ] }, "reaction_10686409": { "compartment": "compartment_7660", "id": "reaction_10686409", "reactome": "R-PFA-68637", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10686407" ], "modifiers": [], "additional_components": [ "PF3D7_0503200" ] }, "reaction_10692172": { "compartment": "compartment_70101", "id": "reaction_10692172", "reactome": "R-PFA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692164" ], "products": [ "species_10692170" ], "modifiers": [], "additional_components": [ "Q8IBK6", "PF3D7_0724600", "Q8IBK6", "PF3D7_0724600" ] }, "reaction_10693514": { "compartment": "compartment_70101", "id": "reaction_10693514", "reactome": "R-PFA-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693510" ], "products": [ "species_10693512" ], "modifiers": [], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "CHEBI:60627", "CHEBI:60628", "CHEBI:59092", "CHEBI:60629", "CHEBI:59087", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10694711": { "compartment": "compartment_70101", "id": "reaction_10694711", "reactome": "R-PFA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_179838" ], "products": [ "species_10688824" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "Q8IIE7", "PF3D7_1121900", "species_179838" ] }, "reaction_10693565": { "compartment": "compartment_70101", "id": "reaction_10693565", "reactome": "R-PFA-1250280", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688320", "species_1250243" ], "products": [ "species_10688318" ], "modifiers": [], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500" ] }, "reaction_10700704": { "compartment": "compartment_6799351", "id": "reaction_10700704", "reactome": "R-PFA-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700690" ], "products": [ "species_10700702" ], "modifiers": [], "additional_components": [ "Q8IDS0", "PF3D7_1341900", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8II31", "PF3D7_1133300", "Q8IJB1", "PF3D7_1133300", "O97295", "PF3D7_0322300", "C0H5C6", "PF3D7_1320500", "Q8ILE6", "PF3D7_1431900", "Q7KWJ5", "PF3D7_0919500", "Q8IL28", "PF3D7_1444300", "Q8IDL8", "PF3D7_1348100", "Q8I2V8", "PF3D7_0919500", "Q8IEK4", "PF3D7_1311400", "Q8I4T2", "PF3D7_1250200", "Q8I4U9", "PF3D7_1248500", "Q8I5L4", "PF3D7_1468600", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILE6", "PF3D7_1431900", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500", "Q8IEK4", "PF3D7_1311400", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IL28", "PF3D7_1444300", "Q8I4U9", "PF3D7_1248500", "Q8IDL8", "PF3D7_1348100", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "O97295", "PF3D7_0322300", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10700208": { "compartment": "compartment_6799713", "id": "reaction_10700208", "reactome": "R-PFA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700192" ], "products": [ "species_10700206" ], "modifiers": [], "additional_components": [ "Q8I3R7", "PF3D7_0519200", "Q7KWJ5", "PF3D7_0919500", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILG6", "PF3D7_1429800", "Q8I3M7", "PF3D7_0523800", "Q8I5R9", "PF3D7_1357300", "Q8IBG2", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILG6", "PF3D7_1429800", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q7KWJ5", "PF3D7_0919500", "Q8I3R7", "PF3D7_0519200", "Q8I3M7", "PF3D7_0523800" ] }, "reaction_10700629": { "compartment": "compartment_1470028", "id": "reaction_10700629", "reactome": "R-PFA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700591" ], "products": [ "species_10700627" ], "modifiers": [], "additional_components": [ "Q8IM42", "PF3D7_1405200", "O96220", "PF3D7_0214000", "Q7KQL5", "PF10_0084", "C6KT34", "PF3D7_0619400", "Q8IKH3", "PF3D7_1466300", "C6KSW6", "PF3D7_0822500", "Q8I412", "PF3D7_0822500", "Q8IB59", "PF3D7_0822500", "Q8IAM2", "PF3D7_0802200", "Q8I1V9", "PF3D7_0409900", "C6KTC6", "PF3D7_0629100", "Q8I384", "PF3D7_0906500", "Q8ID33", "PF3D7_1367500", "Q8ILI2", "PF3D7_1428300", "Q8IM55", "PF3D7_1403900", "Q8I501", "PF3D7_1242800", "O96166", "PF3D7_0207900", "O97247", "PF3D7_0306800", "Q8I2H1", "PF3D7_0934700", "Q8ID33", "PF3D7_1367500", "Q8I384", "PF3D7_0906500", "C6KSW6", "PF3D7_0822500", "Q8IB59", "PF3D7_0822500", "Q8I412", "PF3D7_0822500", "Q8ILI2", "PF3D7_1428300", "C6KTC6", "PF3D7_0629100", "Q8IM42", "PF3D7_1405200", "C6KT34", "PF3D7_0619400", "O97247", "PF3D7_0306800", "O96220", "PF3D7_0214000", "Q7KQL5", "PF10_0084", "Q8IKH3", "PF3D7_1466300", "Q8IAM2", "PF3D7_0802200", "Q8I501", "PF3D7_1242800", "Q8I1V9", "PF3D7_0409900", "O96166", "PF3D7_0207900", "Q8IM55", "PF3D7_1403900", "Q8I2H1", "PF3D7_0934700" ] }, "reaction_10700075": { "compartment": "compartment_876", "id": "reaction_10700075", "reactome": "R-PFA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700049" ], "products": [ "species_10700073" ], "modifiers": [], "additional_components": [ "C6KT12", "PF3D7_1246300", "Q7K6B0", "PF3D7_0807300", "Q76NM7", "PF3D7_1310600", "Q7KWJ5", "PF3D7_0919500", "O97278", "PF3D7_0319700", "Q8ILG6", "PF3D7_1429800", "Q8I274", "PF3D7_0211200", "C0H516", "PF3D7_0903200", "Q8IHR8", "PF3D7_1144900", "Q8IAQ8", "PF3D7_0806800", "C0H4M1", "PF3D7_0707400", "Q8I385", "PF3D7_0906400", "Q8I274", "PF3D7_0211200", "O97278", "PF3D7_0319700", "Q76NM7", "PF3D7_1310600", "C0H516", "PF3D7_0903200", "Q8IHR8", "PF3D7_1144900", "Q7KWJ5", "PF3D7_0919500", "C6KT12", "PF3D7_1246300", "C0H4M1", "PF3D7_0707400", "Q8ILG6", "PF3D7_1429800", "Q8I385", "PF3D7_0906400", "Q8IAQ8", "PF3D7_0806800", "Q7K6B0", "PF3D7_0807300" ] }, "reaction_10700489": { "compartment": "compartment_1462052", "id": "reaction_10700489", "reactome": "R-PFA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700371" ], "products": [ "species_10700487" ], "modifiers": [], "additional_components": [ "Q8IL68", "PF3D7_1440300", "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "Q8IE53", "PF3D7_1329400", "C0H568", "PF3D7_0927500", "Q8IBH5", "PF3D7_1110700", "A0A143ZXR3", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8I0P6", "PF3D7_1357000", "Q8IB94", "PF3D7_0826100", "Q7KQL9", "PF14_0425", "Q8IIA3", "PF3D7_1126100", "Q8IKW5", "PF3D7_1451100", "Q8IAU1", "PF3D7_0810600", "Q8ILA4", "PF3D7_1436000", "Q8I323", "PF3D7_0912900", "Q8IJS0", "PF3D7_1012500", "Q8IDR5", "PF3D7_1342400", "Q8IC05", "PF3D7_1443900", "A0A5K1K9F3", "PF3D7_1338100", "Q8IB24", "PF3D7_0818900", "Q8II71", "PF3D7_1129200", "Q8ID28", "PF3D7_1368100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "O96153", "PF3D7_0205900", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IJM0", "PF3D7_1017900", "Q8IJA0", "PF3D7_1030500", "Q8I616", "PF3D7_1202900", "Q8IEK3", "PF3D7_1311500", "C6KT76", "PF3D7_0624000", "Q8IM66", "PF3D7_1402300", "C6KST3", "PF3D7_0608500", "Q8I613", "PF3D7_1203200", "Q8I6T3", "PF3D7_1328100", "Q8II60", "PF3D7_1130400", "A0A5K1K7U1", "PF3D7_0518300", "C6KT01", "PF3D7_0616000", "Q8IBI3", "PF3D7_0727400", "C6KT34", "PF3D7_0619400", "O96220", "PF3D7_0214000", "Q8IIG6", "PF3D7_1120100", "Q8ID43", "PF3D7_1366500", "Q8I5C5", "PF3D7_1229400", "Q8I5Q4", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q76NN7", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "Q8I501", "PF3D7_1242800", "Q8IM66", "PF3D7_1402300", "Q8I0P6", "PF3D7_1357000", "Q8IJM0", "PF3D7_1017900", "Q8IB94", "PF3D7_0826100", "Q8I5C5", "PF3D7_1229400", "Q8II60", "PF3D7_1130400", "Q8IJS0", "PF3D7_1012500", "Q8IEK3", "PF3D7_1311500", "Q8IKW5", "PF3D7_1451100", "C6KT34", "PF3D7_0619400", "Q8IB24", "PF3D7_0818900", "Q8I613", "PF3D7_1203200", "Q8ILA4", "PF3D7_1436000", "O96220", "PF3D7_0214000", "C6KT01", "PF3D7_0616000", "Q8IC05", "PF3D7_1443900", "Q8I501", "PF3D7_1242800", "C6KT76", "PF3D7_0624000", "Q8IL32", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "Q8IE53", "PF3D7_1329400", "Q8I6T3", "PF3D7_1328100", "A0A143ZXR3", "PF3D7_1110700", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8I616", "PF3D7_1202900", "Q8IIA3", "PF3D7_1126100", "Q8IBI3", "PF3D7_0727400", "Q8IAU1", "PF3D7_0810600", "C6KST3", "PF3D7_0608500", "Q8ID43", "PF3D7_1366500", "Q8IDR5", "PF3D7_1342400", "A0A5K1K7U1", "PF3D7_0518300", "Q8IIG6", "PF3D7_1120100", "Q76NN7", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "Q7KQL9", "PF14_0425", "Q8II71", "PF3D7_1129200", "Q8I323", "PF3D7_0912900", "O96153", "PF3D7_0205900", "C6KTA4", "PF3D7_1037100", "Q8IJ37", "PF3D7_1037100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "A0A5K1K9F3", "PF3D7_1338100", "Q8IJA0", "PF3D7_1030500", "C0H568", "PF3D7_0927500", "Q8ID28", "PF3D7_1368100", "Q8IL68", "PF3D7_1440300" ] }, "reaction_10700520": { "compartment": "compartment_6799371", "id": "reaction_10700520", "reactome": "R-PFA-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700508" ], "products": [ "species_10700518" ], "modifiers": [], "additional_components": [ "C6KT01", "PF3D7_0616000", "Q8IAY9", "PF3D7_0815200", "Q8I384", "PF3D7_0906500", "Q8I509", "PF3D7_1242000", "Q8I1Y2", "PF3D7_0404700", "Q8I6Z5", "PF3D7_1323500", "Q8I486", "PF3D7_0501400", "Q8I384", "PF3D7_0906500", "Q8I486", "PF3D7_0501400", "Q8I6Z5", "PF3D7_1323500", "Q8I509", "PF3D7_1242000", "Q8I1Y2", "PF3D7_0404700", "Q8IAY9", "PF3D7_0815200", "C6KT01", "PF3D7_0616000" ] }, "reaction_10700136": { "compartment": "compartment_6800173", "id": "reaction_10700136", "reactome": "R-PFA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700108" ], "products": [ "species_10700134" ], "modifiers": [], "additional_components": [ "Q8I509", "PF3D7_1242000", "Q8I2Q2", "PF3D7_0925600", "Q8I6Z5", "PF3D7_1323500", "Q7KQL9", "PF14_0425", "Q8I6U4", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q7KQL9", "PF14_0425", "Q8I6Z5", "PF3D7_1323500", "Q8I509", "PF3D7_1242000", "Q8IIL0", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8I2Q2", "PF3D7_0925600" ] }, "reaction_10700943": { "compartment": "compartment_984", "id": "reaction_10700943", "reactome": "R-PFA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700933" ], "products": [ "species_10700941" ], "modifiers": [], "additional_components": [ "Q8IKW5", "PF3D7_1451100", "C0H568", "PF3D7_0927500", "Q8IB94", "PF3D7_0826100", "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "Q8IL68", "PF3D7_1440300", "Q76NN7", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "A0A5K1K7U1", "PF3D7_0518300", "Q8ID28", "PF3D7_1368100", "Q8ID43", "PF3D7_1366500", "O96153", "PF3D7_0205900", "C6KST3", "PF3D7_0608500", "Q8IJM0", "PF3D7_1017900", "Q8IBI3", "PF3D7_0727400", "Q8IJA0", "PF3D7_1030500", "Q8I616", "PF3D7_1202900", "Q8IEK3", "PF3D7_1311500", "Q8I6T3", "PF3D7_1328100", "Q8IM66", "PF3D7_1402300", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "Q8I613", "PF3D7_1203200", "C6KT76", "PF3D7_0624000", "Q8II60", "PF3D7_1130400", "C6KT34", "PF3D7_0619400", "Q8ILA4", "PF3D7_1436000", "Q8IB24", "PF3D7_0818900", "Q7KQL9", "PF14_0425", "Q8IJS0", "PF3D7_1012500", "Q8IIA3", "PF3D7_1126100", "P62203", "PF14_0323", "Q8IE53", "PF3D7_1329400", "Q8IAU1", "PF3D7_0810600", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "A0A143ZXR3", "PF3D7_1110700", "O97289", "PF3D7_0321500", "Q8I1V9", "PF3D7_0409900", "Q8IAY9", "PF3D7_0815200", "O96220", "PF3D7_0214000", "Q8I323", "PF3D7_0912900", "Q8I2Q2", "PF3D7_0925600", "Q8IIG6", "PF3D7_1120100", "A0A5K1K9F3", "PF3D7_1338100", "Q8I5C5", "PF3D7_1229400", "Q8II71", "PF3D7_1129200", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "Q8I1Y2", "PF3D7_0404700", "Q8I6Z5", "PF3D7_1323500", "Q8IDR5", "PF3D7_1342400", "Q8IIJ9", "PF11_0174", "Q8I0P6", "PF3D7_1357000", "Q8IAY9", "PF3D7_0815200", "Q8IJA0", "PF3D7_1030500", "A0A5K1K9F3", "PF3D7_1338100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "O96153", "PF3D7_0205900", "Q8I323", "PF3D7_0912900", "Q8II71", "PF3D7_1129200", "Q8I6Z5", "PF3D7_1323500", "Q8I1V9", "PF3D7_0409900", "Q7KQL9", "PF14_0425", "Q8I2Q2", "PF3D7_0925600", "Q8IIG6", "PF3D7_1120100", "A0A5K1K7U1", "PF3D7_0518300", "Q8ID43", "PF3D7_1366500", "Q8IAU1", "PF3D7_0810600", "Q8IIA3", "PF3D7_1126100", "A0A143ZXR3", "PF3D7_1110700", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8IE53", "PF3D7_1329400", "O96220", "PF3D7_0214000", "Q8I613", "PF3D7_1203200", "C6KT34", "PF3D7_0619400", "Q8I1Y2", "PF3D7_0404700", "Q8IEK3", "PF3D7_1311500", "Q8II60", "PF3D7_1130400", "Q8I5C5", "PF3D7_1229400", "Q8IJM0", "PF3D7_1017900", "Q8IM66", "PF3D7_1402300", "Q8IL68", "PF3D7_1440300", "C0H568", "PF3D7_0927500", "C6KTA4", "PF3D7_1037100", "Q8IJ37", "PF3D7_1037100", "Q8IIK8", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q76NN7", "PF3D7_1215200", "P62203", "PF14_0323", "Q8IIJ9", "PF11_0174", "O97289", "PF3D7_0321500", "Q8IDR5", "PF3D7_1342400", "C6KST3", "PF3D7_0608500", "Q8IBI3", "PF3D7_0727400", "Q8I616", "PF3D7_1202900", "Q8I6T3", "PF3D7_1328100", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "C6KT76", "PF3D7_0624000", "Q8ILA4", "PF3D7_1436000", "Q8IB24", "PF3D7_0818900", "Q8IKW5", "PF3D7_1451100", "Q8IJS0", "PF3D7_1012500", "Q8IB94", "PF3D7_0826100", "Q8I0P6", "PF3D7_1357000", "Q8ID28", "PF3D7_1368100" ] }, "reaction_10699997": { "compartment": "compartment_6798757", "id": "reaction_10699997", "reactome": "R-PFA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699963" ], "products": [ "species_10699995" ], "modifiers": [], "additional_components": [ "Q8I3R7", "PF3D7_0519200", "Q8IL71", "PF3D7_1439800", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "O97278", "PF3D7_0319700", "Q8I2V7", "PF3D7_0919600", "B9ZSI6", "PF3D7_0107700", "O96171", "PF3D7_0208400", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IDL8", "PF3D7_1348100", "Q8I310", "PF3D7_0914200", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "C0H5C6", "PF3D7_1320500", "Q8I3F8", "PF3D7_0531000", "O96171", "PF3D7_0208400", "Q8I5L4", "PF3D7_1468600", "O97278", "PF3D7_0319700", "Q8I3F8", "PF3D7_0531000", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "Q8I3R7", "PF3D7_0519200", "C0H5C6", "PF3D7_1320500", "Q8IL71", "PF3D7_1439800", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IDL8", "PF3D7_1348100", "Q8I2V7", "PF3D7_0919600", "B9ZSI6", "PF3D7_0107700", "Q8I310", "PF3D7_0914200" ] }, "reaction_10700781": { "compartment": "compartment_6800424", "id": "reaction_10700781", "reactome": "R-PFA-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700769" ], "products": [ "species_10700779" ], "modifiers": [], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I385", "PF3D7_0906400", "C6KT12", "PF3D7_1246300", "Q8IIL9", "PF3D7_1114200", "Q8I379", "PF3D7_1114200", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8ILG6", "PF3D7_1429800", "Q8I3M7", "PF3D7_0523800", "C0H4M1", "PF3D7_0707400", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "C6KT12", "PF3D7_1246300", "C0H4M1", "PF3D7_0707400", "Q8I379", "PF3D7_1114200", "Q8IIL9", "PF3D7_1114200", "Q8ILG6", "PF3D7_1429800", "Q8I385", "PF3D7_0906400", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8IAQ8", "PF3D7_0806800", "Q7KWJ5", "PF3D7_0919500", "Q8I3R7", "PF3D7_0519200", "Q8I3M7", "PF3D7_0523800" ] }, "reaction_10701410": { "compartment": "compartment_984", "id": "reaction_10701410", "reactome": "R-PFA-6810724", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803081", "species_10701406" ], "products": [ "species_10701408" ], "modifiers": [], "additional_components": [ "Q8I486", "PF3D7_0501400", "Q8I486", "PF3D7_0501400", "species_166005" ] }, "reaction_10701031": { "compartment": "compartment_984", "id": "reaction_10701031", "reactome": "R-PFA-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_181015", "species_10701027" ], "products": [ "species_10701029" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "Q8I616", "PF3D7_1202900", "species_181015" ] }, "reaction_10701035": { "compartment": "compartment_984", "id": "reaction_10701035", "reactome": "R-PFA-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10701027" ], "products": [ "species_10701033" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "Q8I616", "PF3D7_1202900", "species_166005" ] }, "reaction_10701162": { "compartment": "compartment_984", "id": "reaction_10701162", "reactome": "R-PFA-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690933" ], "products": [ "species_10701027" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "PF3D7_1202900" ] }, "reaction_10703347": { "compartment": "compartment_70101", "id": "reaction_10703347", "reactome": "R-PFA-9013869", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694974", "species_8982080" ], "products": [ "species_10703345" ], "modifiers": [], "additional_components": [ "PF3D7_0527900", "CHEBI:49537", "CHEBI:47037", "CHEBI:49537", "CHEBI:47037", "A0A5K1K8X8", "PF3D7_0527900" ] }, "reaction_10694983": { "compartment": "compartment_70101", "id": "reaction_10694983", "reactome": "R-PFA-3134962", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3134861", "species_10694979" ], "products": [ "species_10694981" ], "modifiers": [], "additional_components": [ "PF3D7_0310500", "O77360", "PF3D7_0310500" ] }, "reaction_10690562": { "compartment": "compartment_70101", "id": "reaction_10690562", "reactome": "R-PFA-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_202277" ], "products": [ "species_10690560" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "species_202247", "species_179838", "Q8IIE7", "PF3D7_1121900", "species_202247", "species_179838" ] }, "reaction_10693549": { "compartment": "compartment_1222693", "id": "reaction_10693549", "reactome": "R-PFA-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10693546", "catalyst" ] ], "additional_components": [ "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900", "Q8IKJ0", "PF3D7_1464700", "Q8IDF7", "PF3D7_1354400", "C0H4P0", "PF3D7_0721900", "Q8IAQ8", "PF3D7_0806800", "Q8I3R7", "PF3D7_0519200" ] }, "reaction_10688366": { "compartment": "compartment_70101", "id": "reaction_10688366", "reactome": "R-PFA-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_111584", "species_29472" ], "products": [ "species_111294", "species_29404", "species_113578", "species_76577" ], "modifiers": [ [ "species_10688363", "catalyst" ] ], "additional_components": [ "PF3D7_1012600" ] }, "reaction_10689181": { "compartment": "compartment_70101", "id": "reaction_10689181", "reactome": "R-PFA-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29448", "species_29602" ], "products": [ "species_29372", "species_29420", "species_35141" ], "modifiers": [ [ "species_10689178", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_30014", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_113578", "inhibitor" ] ], "additional_components": [ "species_29926", "Q8IDF6", "PF13_0287" ] }, "reaction_10698331": { "compartment": "compartment_7660", "id": "reaction_10698331", "reactome": "R-PFA-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698328", "species_30555" ], "products": [ "species_10698326", "species_113541" ], "modifiers": [ [ "species_10698328", "catalyst" ] ], "additional_components": [ "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10690535": { "compartment": "compartment_70101", "id": "reaction_10690535", "reactome": "R-PFA-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10690512" ], "products": [ "species_29370", "species_10690533" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "Q8IC05", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "P62203", "PF14_0323", "species_74016", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10693927": { "compartment": "compartment_70101", "id": "reaction_10693927", "reactome": "R-PFA-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10690533" ], "products": [ "species_10690537" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10689795": { "compartment": "compartment_70101", "id": "reaction_10689795", "reactome": "R-PFA-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_174390" ], "products": [ "species_111294", "species_29372", "species_71284" ], "modifiers": [ [ "species_10689792", "catalyst" ] ], "additional_components": [ "species_29926", "Q7K6A4", "PF3D7_0922200", "species_74126" ] }, "reaction_10689813": { "compartment": "compartment_70101", "id": "reaction_10689813", "reactome": "R-PFA-175983", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175977", "species_71284" ], "products": [ "species_175978", "species_71285" ], "modifiers": [ [ "species_10689810", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10700735": { "compartment": "compartment_70101", "id": "reaction_10700735", "reactome": "R-PFA-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10700729", "catalyst" ] ], "additional_components": [ "Q8IET4", "PF3D7_1303100", "Q8IM19", "PF3D7_1407500" ] }, "reaction_10698363": { "compartment": "compartment_70101", "id": "reaction_10698363", "reactome": "R-PFA-5692232", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_5692212" ], "products": [ "species_5692216", "species_29364" ], "modifiers": [ [ "species_10697185", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10689805": { "compartment": "compartment_70101", "id": "reaction_10689805", "reactome": "R-PFA-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174393", "species_113592", "species_29424" ], "products": [ "species_29372", "species_29370", "species_29450" ], "modifiers": [ [ "species_10689802", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "species_29926", "Q8I3Y4", "PF3D7_0512200" ] }, "reaction_10689823": { "compartment": "compartment_70101", "id": "reaction_10689823", "reactome": "R-PFA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_176070" ], "products": [ "species_176049" ], "modifiers": [ [ "species_10689820", "catalyst" ] ], "additional_components": [ "CHEBI:29132", "CHEBI:34718", "CHEBI:30614", "CHEBI:8927", "CHEBI:32639", "CHEBI:34479", "Q8ILQ7", "PF14_0187" ] }, "reaction_10687505": { "compartment": "compartment_70101", "id": "reaction_10687505", "reactome": "R-PFA-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29416", "species_76194" ], "products": [ "species_111294", "species_76183", "species_76577" ], "modifiers": [ [ "species_10687502", "catalyst" ] ], "additional_components": [ "PF3D7_0627800" ] }, "reaction_10692132": { "compartment": "compartment_5460", "id": "reaction_10692132", "reactome": "R-PFA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_113539" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10692129", "catalyst" ] ], "additional_components": [ "PF3D7_0627800" ] }, "reaction_10689254": { "compartment": "compartment_7660", "id": "reaction_10689254", "reactome": "R-PFA-111915", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10689245" ], "products": [ "species_113582", "species_10689251" ], "modifiers": [ [ "species_10689245", "catalyst" ] ], "additional_components": [ "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323", "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323", "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10691885": { "compartment": "compartment_70101", "id": "reaction_10691885", "reactome": "R-PFA-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10691877" ], "products": [ "species_113582", "species_10691882" ], "modifiers": [ [ "species_10691877", "catalyst" ] ], "additional_components": [ "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10699811": { "compartment": "compartment_70101", "id": "reaction_10699811", "reactome": "R-PFA-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699781", "species_10699783" ], "products": [ "species_10699789", "species_10699791", "species_10699785", "species_10699803", "species_10699787", "species_10699797", "species_10687798", "species_10699783", "species_10699793", "species_10691650", "species_10699795" ], "modifiers": [ [ "species_10699789", "catalyst" ], [ "species_10699809", "catalyst" ], [ "species_10699803", "catalyst" ], [ "species_10691650", "catalyst" ] ], "additional_components": [ "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IM10", "PF3D7_1408600", "Q8IDR9", "PF3D7_1342000", "Q8IKL9", "PF3D7_1461300", "O97313", "PFC1020c", "Q8I1N8", "PF3D7_0420100", "Q8IAX5", "PF3D7_0813900", "Q8IKE4", "PF3D7_1469300", "O97248", "PF3D7_0306900", "Q8IDB0", "PF3D7_1358800", "Q8I1Q0", "PF3D7_0418700", "O77395", "PF3D7_0316800", "O96224", "PF3D7_0214400", "O77381", "PF3D7_0317600", "C6KT53", "PF3D7_0621500", "Q8IDN4", "PF3D7_1346300", "Q8IAX8", "PF3D7_1346300", "Q8IIR2", "PF3D7_1109400", "Q8IIU8", "PF3D7_1105400", "Q8IEN2", "PF3D7_1308300", "Q8I3R6", "PF3D7_0519400", "Q8IE34", "PF3D7_1327200", "Q8IKH8", "PF3D7_1465900", "Q8IJD4", "PF10_0264", "Q7KQK2", "PF3D7_1402500", "C0H4K8", "PF3D7_0705700", "Q8ILN8", "PF3D7_1421200", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2", "O96258", "PF3D7_0217800", "Q8IK02", "PF3D7_1003500", "Q8IHS5", "PF3D7_1144000", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "C0H5C2", "PF3D7_1317800", "A0A5K1K925", "PF3D7_0516200", "A0A144A2N6", "PF3D7_1230900", "Q8I502", "PF3D7_1242700", "Q8IKV7", "PF3D7_1451900", "Q8IBQ5", "PF3D7_0719700", "Q8IET7", "PF3D7_1302800", "O97249", "PF3D7_0307100", "Q8I3R0", "PF3D7_0520000", "PF3D7_1230900", "PF3D7_0418700", "PF3D7_1469300", "PF3D7_1109400", "C6S3F7", "PF3D7_1136500.2", "Q8IHZ9", "PF3D7_1136500.1", "PF3D7_0214400", "PF3D7_1230900", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "PF3D7_1230900", "PF3D7_0420100", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2", "PF3D7_1451900", "PF3D7_0418700", "PF3D7_0522300", "C6S3F7", "PF3D7_1136500.2", "Q8IHZ9", "PF3D7_1136500.1", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2" ] }, "reaction_10697067": { "compartment": "compartment_17963", "id": "reaction_10697067", "reactome": "R-PFA-5653873", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_964746" ], "modifiers": [ [ "species_10697064", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10694064": { "compartment": "compartment_171062", "id": "reaction_10694064", "reactome": "R-PFA-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10701695": { "compartment": "compartment_70101", "id": "reaction_10701695", "reactome": "R-PFA-8849969", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8849959" ], "products": [ "species_29372", "species_8849958" ], "modifiers": [ [ "species_10701692", "catalyst" ] ], "additional_components": [ "species_179838", "species_202247", "species_179856", "species_1806200", "species_1806224", "species_1806240", "PF3D7_1354200" ] }, "reaction_10694096": { "compartment": "compartment_876", "id": "reaction_10694096", "reactome": "R-PFA-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10693987", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694013": { "compartment": "compartment_876", "id": "reaction_10694013", "reactome": "R-PFA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806240", "species_113592" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10694010", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10688787": { "compartment": "compartment_7660", "id": "reaction_10688787", "reactome": "R-PFA-77584", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688783", "species_10688778" ], "products": [ "species_10688785" ], "modifiers": [], "additional_components": [ "PF3D7_0927600", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I2N3", "PF3D7_0927600" ] }, "reaction_10689594": { "compartment": "compartment_876", "id": "reaction_10689594", "reactome": "R-PFA-165026", "name": "OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164988", "species_74113" ], "products": [ "species_30235", "species_83910" ], "modifiers": [ [ "species_10689591", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10688242": { "compartment": "compartment_70101", "id": "reaction_10688242", "reactome": "R-PFA-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687916", "species_10687864", "species_10687881", "species_72617", "species_10687921" ], "products": [ "species_10687916", "species_10687864", "species_10687881", "species_72617", "species_10687921" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "PF3D7_1206700", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "PF3D7_1206700" ] }, "reaction_10687927": { "compartment": "compartment_70101", "id": "reaction_10687927", "reactome": "R-PFA-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687916", "species_113592" ], "products": [ "species_10687916", "species_29372", "species_29370" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10688234": { "compartment": "compartment_70101", "id": "reaction_10688234", "reactome": "R-PFA-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687864", "species_10688215" ], "products": [ "species_10687864", "species_10688213", "species_10687798" ], "modifiers": [], "additional_components": [ "PF3D7_1143400", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "PF3D7_1143400", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600" ] }, "reaction_10688238": { "compartment": "compartment_70101", "id": "reaction_10688238", "reactome": "R-PFA-72676", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687864", "species_10687798", "species_10687859" ], "products": [ "species_10688236" ], "modifiers": [], "additional_components": [ "PF3D7_1143400", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400" ] }, "reaction_10687937": { "compartment": "compartment_70101", "id": "reaction_10687937", "reactome": "R-PFA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687883", "species_72393" ], "products": [ "species_10687885" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10688240": { "compartment": "compartment_70101", "id": "reaction_10688240", "reactome": "R-PFA-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688236", "species_10687885" ], "products": [ "species_10687887" ], "modifiers": [], "additional_components": [ "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10687935": { "compartment": "compartment_70101", "id": "reaction_10687935", "reactome": "R-PFA-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10687881" ], "products": [ "species_10687883" ], "modifiers": [], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10687929": { "compartment": "compartment_70101", "id": "reaction_10687929", "reactome": "R-PFA-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687903", "species_10687898", "species_10687908" ], "products": [ "species_10687910" ], "modifiers": [], "additional_components": [ "PF3D7_0315100", "Q8IKF0", "PF3D7_1468700", "PF3D7_1107300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100" ] }, "reaction_10688230": { "compartment": "compartment_70101", "id": "reaction_10688230", "reactome": "R-PFA-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688224" ], "products": [ "species_29372", "species_10688228", "species_10688226" ], "modifiers": [], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29438", "C6KSR8", "PF3D7_0607000", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29420", "C6KSR8", "PF3D7_0607000" ] }, "reaction_10688232": { "compartment": "compartment_70101", "id": "reaction_10688232", "reactome": "R-PFA-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688222", "species_10688213", "species_10687923" ], "products": [ "species_10688224" ], "modifiers": [], "additional_components": [ "species_29438", "C6KSR8", "PF3D7_0607000", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29438", "C6KSR8", "PF3D7_0607000" ] }, "reaction_10687968": { "compartment": "compartment_70101", "id": "reaction_10687968", "reactome": "R-PFA-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687964", "species_10687925" ], "products": [ "species_10687966" ], "modifiers": [], "additional_components": [ "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400" ] }, "reaction_10688245": { "compartment": "compartment_70101", "id": "reaction_10688245", "reactome": "R-PFA-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10687966" ], "products": [ "species_10687964", "species_29420", "species_10687883" ], "modifiers": [ [ "species_10687964", "catalyst" ] ], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400" ] }, "reaction_10689620": { "compartment": "compartment_70101", "id": "reaction_10689620", "reactome": "R-PFA-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10687908" ], "products": [ "species_29370", "species_10689618" ], "modifiers": [ [ "species_10689603", "catalyst" ] ], "additional_components": [ "PF3D7_1107300", "PF3D7_1107300", "PF3D7_1246900" ] }, "reaction_10689613": { "compartment": "compartment_70101", "id": "reaction_10689613", "reactome": "R-PFA-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10687760" ], "products": [ "species_29370", "species_10689610" ], "modifiers": [ [ "species_10689603", "catalyst" ] ], "additional_components": [ "PF3D7_1342000", "PF3D7_1342000", "PF3D7_1246900" ] }, "reaction_10702534": { "compartment": "compartment_876", "id": "reaction_10702534", "reactome": "R-PFA-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10693985", "catalyst" ] ], "additional_components": [ "PF3D7_0110600" ] }, "reaction_10702417": { "compartment": "compartment_70101", "id": "reaction_10702417", "reactome": "R-PFA-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702413", "species_10702401" ], "products": [ "species_10702415" ], "modifiers": [], "additional_components": [ "O97322", "PF3D7_1025000", "Q8IJF4", "PF3D7_1025000", "Q8I4X4", "PF3D7_1245800", "Q8II45", "PF3D7_1132000", "Q8IIM8", "PF3D7_1132000", "Q8I2T2", "PF3D7_1132000", "Q8II45", "PF3D7_1132000", "Q8IIM8", "PF3D7_1132000", "Q8I2T2", "PF3D7_1132000", "O97322", "PF3D7_1025000", "Q8IJF4", "PF3D7_1025000", "Q8I4X4", "PF3D7_1245800" ] }, "reaction_10702263": { "compartment": "compartment_70101", "id": "reaction_10702263", "reactome": "R-PFA-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698282", "species_10702261" ], "products": [ "species_10702247" ], "modifiers": [], "additional_components": [ "PF3D7_1313000", "Q8IL63", "PF3D7_1440700", "Q8I5M5", "PF3D7_1440700", "Q8I5M5", "PF3D7_1440700", "Q8IL63", "PF3D7_1440700" ] }, "reaction_10703640": { "compartment": "compartment_70101", "id": "reaction_10703640", "reactome": "R-PFA-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10702203" ], "products": [ "species_10703638" ], "modifiers": [], "additional_components": [ "Q8I3I6", "PF3D7_0528100", "C6KT12", "PF3D7_1246300", "Q8I4W9", "PF3D7_1246300", "Q8I5M5", "PF3D7_1440700", "O96254", "PF3D7_0217300", "Q8I3I6", "PF3D7_0528100", "C6KT12", "PF3D7_1246300", "Q8I4W9", "PF3D7_1246300", "Q8I5M5", "PF3D7_1440700", "O96254", "PF3D7_0217300" ] }, "reaction_10694563": { "compartment": "compartment_5460", "id": "reaction_10694563", "reactome": "R-PFA-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162265", "species_2162212" ], "products": [ "species_2162252", "species_113529", "species_2162198" ], "modifiers": [ [ "species_10694560", "catalyst" ] ], "additional_components": [ "PF3D7_0724300" ] }, "reaction_10694571": { "compartment": "compartment_70616", "id": "reaction_10694571", "reactome": "R-PFA-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10694568", "catalyst" ] ], "additional_components": [ "PF3D7_0607500" ] }, "reaction_10694574": { "compartment": "compartment_5460", "id": "reaction_10694574", "reactome": "R-PFA-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162265", "species_2162209" ], "products": [ "species_2162252", "species_113529", "species_2162215" ], "modifiers": [ [ "species_10694560", "catalyst" ] ], "additional_components": [ "PF3D7_0724300" ] }, "reaction_10694588": { "compartment": "compartment_5460", "id": "reaction_10694588", "reactome": "R-PFA-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162257", "species_2162256" ], "products": [ "species_159450", "species_2162214" ], "modifiers": [ [ "species_10694585", "catalyst" ] ], "additional_components": [ "O96130", "PF3D7_0202700", "species_29926" ] }, "reaction_10688699": { "compartment": "compartment_7660", "id": "reaction_10688699", "reactome": "R-PFA-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688694", "species_30595" ], "products": [ "species_10688696", "species_113541" ], "modifiers": [ [ "species_10687614", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10689161": { "compartment": "compartment_7660", "id": "reaction_10689161", "reactome": "R-PFA-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688696", "species_30595" ], "products": [ "species_113541", "species_10688727" ], "modifiers": [ [ "species_10687614", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10694756": { "compartment": "compartment_70101", "id": "reaction_10694756", "reactome": "R-PFA-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5357707", "species_113592" ], "products": [ "species_111294", "species_29372", "species_5357652" ], "modifiers": [ [ "species_10689792", "catalyst" ] ], "additional_components": [ "species_29926", "Q7K6A4", "PF3D7_0922200", "species_74126" ] }, "reaction_10703615": { "compartment": "compartment_876", "id": "reaction_10703615", "reactome": "R-PFA-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10703611" ], "products": [ "species_10703613" ], "modifiers": [], "additional_components": [ "Q8I1Z1", "PF3D7_0403800", "C0H4R4", "PF3D7_1120400", "Q8IIG3", "PF3D7_1120400", "Q8I1Z1", "PF3D7_0403800", "C0H4R4", "PF3D7_1120400", "Q8IIG3", "PF3D7_1120400" ] }, "reaction_10703582": { "compartment": "compartment_70101", "id": "reaction_10703582", "reactome": "R-PFA-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703578", "species_9653479" ], "products": [ "species_10703580" ], "modifiers": [], "additional_components": [ "Q8I503", "PF3D7_1242600", "Q8IHP6", "PF3D7_1147500", "Q8I503", "PF3D7_1242600", "Q8IHP6", "PF3D7_1147500" ] }, "reaction_10693680": { "compartment": "compartment_70101", "id": "reaction_10693680", "reactome": "R-PFA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1474124" ], "products": [ "species_1475054", "species_1474179" ], "modifiers": [ [ "species_10693677", "catalyst" ] ], "additional_components": [ "species_216785", "C6KTB6", "PF3D7_0628000" ] }, "reaction_10693669": { "compartment": "compartment_70101", "id": "reaction_10693669", "reactome": "R-PFA-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10693666", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "Q8I5H7", "PF3D7_1224000" ] }, "reaction_10693931": { "compartment": "compartment_70101", "id": "reaction_10693931", "reactome": "R-PFA-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690537", "species_1497857" ], "products": [ "species_29870", "species_10693929" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "species_1497857", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10693695": { "compartment": "compartment_70101", "id": "reaction_10693695", "reactome": "R-PFA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693684" ], "products": [ "species_10693677", "species_29370" ], "modifiers": [ [ "species_10693692", "catalyst" ] ], "additional_components": [ "C6KTB6", "PF3D7_0628000", "species_216785", "C6KTB6", "PF3D7_0628000", "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800" ] }, "reaction_10691489": { "compartment": "compartment_70101", "id": "reaction_10691489", "reactome": "R-PFA-426240", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114519" ], "products": [ "species_76108", "species_29370" ], "modifiers": [ [ "species_10691486", "catalyst" ] ], "additional_components": [ "Q8IKC5", "PF3D7_1471400", "Q8I2K9", "PF3D7_1471400" ] }, "reaction_10698647": { "compartment": "compartment_876", "id": "reaction_10698647", "reactome": "R-PFA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694509" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10698644", "catalyst" ] ], "additional_components": [ "PF3D7_0728700" ] }, "reaction_10692642": { "compartment": "compartment_70101", "id": "reaction_10692642", "reactome": "R-PFA-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692638", "species_10692633" ], "products": [ "species_10692640" ], "modifiers": [], "additional_components": [ "PF3D7_0517600", "PF3D7_0528500", "Q8I3I2", "PF3D7_0528500", "Q8I3T2", "PF3D7_0517600" ] }, "reaction_10693489": { "compartment": "compartment_5460", "id": "reaction_10693489", "reactome": "R-PFA-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113581", "species_113525" ], "modifiers": [ [ "species_10693486", "catalyst" ] ], "additional_components": [ "PF3D7_1008900" ] }, "reaction_10693458": { "compartment": "compartment_70101", "id": "reaction_10693458", "reactome": "R-PFA-984689", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693431" ], "products": [ "species_10693433" ], "modifiers": [], "additional_components": [ "Q8I4X5", "PF3D7_1245600", "Q8I5U0", "PF3D7_1245600", "Q8I4X5", "PF3D7_1245600", "Q8I5U0", "PF3D7_1245600" ] }, "reaction_10693456": { "compartment": "compartment_70101", "id": "reaction_10693456", "reactome": "R-PFA-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693410" ], "products": [ "species_10693412" ], "modifiers": [], "additional_components": [ "PF3D7_0317500", "O77382", "PF3D7_0317500" ] }, "reaction_10693480": { "compartment": "compartment_7660", "id": "reaction_10693480", "reactome": "R-PFA-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693476", "species_10693463" ], "products": [ "species_10693478" ], "modifiers": [], "additional_components": [ "Q8IDZ1", "PF3D7_1333700", "C6KSV0", "PF3D7_0617900", "C6KT19", "PF3D7_0617900", "PF3D7_1220900", "Q8I5K4", "PF3D7_1220900", "Q8IDZ1", "PF3D7_1333700", "C6KSV0", "PF3D7_0617900", "C6KT19", "PF3D7_0617900" ] }, "reaction_10703621": { "compartment": "compartment_70101", "id": "reaction_10703621", "reactome": "R-PFA-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703617" ], "products": [ "species_10703619" ], "modifiers": [], "additional_components": [ "PF3D7_0917100", "PF3D7_0917100" ] }, "reaction_10689008": { "compartment": "compartment_7660", "id": "reaction_10689008", "reactome": "R-PFA-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689003" ], "products": [ "species_5635947", "species_10689005" ], "modifiers": [ [ "species_10689003", "catalyst" ] ], "additional_components": [ "A0A143ZYC4", "PF3D7_1129500", "A0A143ZYC4", "PF3D7_1129500", "A0A143ZYC4", "PF3D7_1129500" ] }, "reaction_10689024": { "compartment": "compartment_7660", "id": "reaction_10689024", "reactome": "R-PFA-110250", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689021" ], "products": [ "species_110249", "species_10689014" ], "modifiers": [ [ "species_10689021", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10689031": { "compartment": "compartment_7660", "id": "reaction_10689031", "reactome": "R-PFA-110251", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689028" ], "products": [ "species_29850", "species_10689014" ], "modifiers": [ [ "species_10689028", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10689017": { "compartment": "compartment_7660", "id": "reaction_10689017", "reactome": "R-PFA-110248", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689012" ], "products": [ "species_10689014", "species_30947" ], "modifiers": [ [ "species_10689012", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10688985": { "compartment": "compartment_7660", "id": "reaction_10688985", "reactome": "R-PFA-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688980" ], "products": [ "species_10688982", "species_110242" ], "modifiers": [ [ "species_10688980", "catalyst" ] ], "additional_components": [ "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100" ] }, "reaction_10689062": { "compartment": "compartment_7660", "id": "reaction_10689062", "reactome": "R-PFA-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10689051" ], "products": [ "species_10689059" ], "modifiers": [ [ "species_10689051", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10689109": { "compartment": "compartment_7660", "id": "reaction_10689109", "reactome": "R-PFA-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689067", "species_10689072" ], "products": [ "species_10689074" ], "modifiers": [], "additional_components": [ "PF3D7_1037000", "PF3D7_1023400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10689083": { "compartment": "compartment_7660", "id": "reaction_10689083", "reactome": "R-PFA-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689076" ], "products": [ "species_10689080", "species_113541", "species_10689074" ], "modifiers": [ [ "species_10689076", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10697018": { "compartment": "compartment_7660", "id": "reaction_10697018", "reactome": "R-PFA-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689074", "species_10689059" ], "products": [ "species_10689076" ], "modifiers": [], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10689053": { "compartment": "compartment_7660", "id": "reaction_10689053", "reactome": "R-PFA-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689036", "species_10689049" ], "products": [ "species_10689051" ], "modifiers": [], "additional_components": [ "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697056": { "compartment": "compartment_7660", "id": "reaction_10697056", "reactome": "R-PFA-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697052", "species_10689135" ], "products": [ "species_10697054" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697153": { "compartment": "compartment_7660", "id": "reaction_10697153", "reactome": "R-PFA-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10697144" ], "products": [ "species_10697150", "species_113541" ], "modifiers": [ [ "species_10697144", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697162": { "compartment": "compartment_7660", "id": "reaction_10697162", "reactome": "R-PFA-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697150", "species_30555" ], "products": [ "species_10689036", "species_113541", "species_10697159", "species_10689074" ], "modifiers": [ [ "species_10697150", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "PF3D7_0910500", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10689107": { "compartment": "compartment_7660", "id": "reaction_10689107", "reactome": "R-PFA-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689097" ], "products": [ "species_113541", "species_10689104" ], "modifiers": [ [ "species_10689097", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697094": { "compartment": "compartment_7660", "id": "reaction_10697094", "reactome": "R-PFA-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697090", "species_10697074" ], "products": [ "species_10697092" ], "modifiers": [], "additional_components": [ "Q8ILR6", "PF3D7_1418000", "C6KT34", "PF3D7_0619400", "Q8I426", "PF3D7_0507700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400", "Q8ILR6", "PF3D7_1418000", "C6KT34", "PF3D7_0619400", "Q8I426", "PF3D7_0507700" ] }, "reaction_10697096": { "compartment": "compartment_7660", "id": "reaction_10697096", "reactome": "R-PFA-5654986", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697072", "species_10689104" ], "products": [ "species_10697074" ], "modifiers": [], "additional_components": [ "PF3D7_1338400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400" ] }, "reaction_10689100": { "compartment": "compartment_7660", "id": "reaction_10689100", "reactome": "R-PFA-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29604", "species_10689091" ], "products": [ "species_10689097", "species_113541" ], "modifiers": [ [ "species_10689091", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697125": { "compartment": "compartment_7660", "id": "reaction_10697125", "reactome": "R-PFA-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697116", "species_30555" ], "products": [ "species_113541", "species_10697122" ], "modifiers": [ [ "species_10697116", "catalyst" ] ], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697134": { "compartment": "compartment_7660", "id": "reaction_10697134", "reactome": "R-PFA-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10697122" ], "products": [ "species_10689036", "species_10697131", "species_113541", "species_10689074" ], "modifiers": [ [ "species_10697122", "catalyst" ] ], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500", "PF3D7_0910500", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500" ] }, "reaction_10703478": { "compartment": "compartment_70101", "id": "reaction_10703478", "reactome": "R-PFA-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690526", "species_10703474" ], "products": [ "species_10703476" ], "modifiers": [], "additional_components": [ "species_74016", "P62203", "PF14_0323", "C0H482", "PF3D7_1450000", "Q8IKX5", "PF3D7_1450000", "C0H4K5", "PF3D7_1450000", "C6KSQ1", "PF3D7_1450000", "C0H482", "PF3D7_1450000", "Q8IKX5", "PF3D7_1450000", "C0H4K5", "PF3D7_1450000", "C6KSQ1", "PF3D7_1450000", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10703452": { "compartment": "compartment_70101", "id": "reaction_10703452", "reactome": "R-PFA-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10703445" ], "products": [ "species_29370", "species_10703449" ], "modifiers": [ [ "species_10703445", "catalyst" ] ], "additional_components": [ "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10703397": { "compartment": "compartment_7660", "id": "reaction_10703397", "reactome": "R-PFA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703385" ], "products": [ "species_10703395" ], "modifiers": [], "additional_components": [ "Q8I4W3", "PF3D7_1246900", "Q8I4W3", "PF3D7_1246900" ] }, "reaction_10690163": { "compartment": "compartment_70101", "id": "reaction_10690163", "reactome": "R-PFA-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193707", "species_29364" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690161": { "compartment": "compartment_70101", "id": "reaction_10690161", "reactome": "R-PFA-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690159": { "compartment": "compartment_70101", "id": "reaction_10690159", "reactome": "R-PFA-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_193707", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690157": { "compartment": "compartment_70101", "id": "reaction_10690157", "reactome": "R-PFA-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193724", "species_70106", "species_29364" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10702531": { "compartment": "compartment_70101", "id": "reaction_10702531", "reactome": "R-PFA-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10702528", "catalyst" ] ], "additional_components": [ "Q8II47", "PF3D7_1131800" ] }, "reaction_10690167": { "compartment": "compartment_70101", "id": "reaction_10690167", "reactome": "R-PFA-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_9617026" ], "products": [ "species_193829", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690165": { "compartment": "compartment_70101", "id": "reaction_10690165", "reactome": "R-PFA-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193829", "species_29364" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690171": { "compartment": "compartment_70101", "id": "reaction_10690171", "reactome": "R-PFA-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690169": { "compartment": "compartment_70101", "id": "reaction_10690169", "reactome": "R-PFA-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10702539": { "compartment": "compartment_70101", "id": "reaction_10702539", "reactome": "R-PFA-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_8868393", "species_1806234" ], "modifiers": [ [ "species_10702536", "catalyst" ] ], "additional_components": [ "PF3D7_1131800" ] }, "reaction_10690146": { "compartment": "compartment_70101", "id": "reaction_10690146", "reactome": "R-PFA-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690150": { "compartment": "compartment_70101", "id": "reaction_10690150", "reactome": "R-PFA-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191980", "species_70106", "species_29364" ], "products": [ "species_192030", "species_29366" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690148": { "compartment": "compartment_70101", "id": "reaction_10690148", "reactome": "R-PFA-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690141": { "compartment": "compartment_70101", "id": "reaction_10690141", "reactome": "R-PFA-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_192136", "species_29364" ], "products": [ "species_191980", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690097": { "compartment": "compartment_70101", "id": "reaction_10690097", "reactome": "R-PFA-191322", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191324", "species_191362" ], "products": [ "species_111294", "species_191409" ], "modifiers": [ [ "species_10690091", "catalyst" ] ], "additional_components": [ "Q8II79", "PF3D7_1128400", "species_29926" ] }, "reaction_10690094": { "compartment": "compartment_70101", "id": "reaction_10690094", "reactome": "R-PFA-191303", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191409", "species_191362" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10690091", "catalyst" ] ], "additional_components": [ "Q8II79", "PF3D7_1128400", "species_29926" ] }, "reaction_10696462": { "compartment": "compartment_17957", "id": "reaction_10696462", "reactome": "R-PFA-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10696459", "catalyst" ] ], "additional_components": [ "PF3D7_1011300" ] }, "reaction_10700978": { "compartment": "compartment_17906", "id": "reaction_10700978", "reactome": "R-PFA-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10700973", "catalyst" ] ], "additional_components": [ "Q8I227", "PF3D7_0111900", "Q8IE73", "PF3D7_1324400" ] }, "reaction_10700975": { "compartment": "compartment_17927", "id": "reaction_10700975", "reactome": "R-PFA-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700971", "species_10700962" ], "products": [ "species_10700973" ], "modifiers": [], "additional_components": [ "Q8IE73", "PF3D7_1324400", "PF3D7_0111900", "Q8I227", "PF3D7_0111900", "Q8IE73", "PF3D7_1324400" ] }, "reaction_10703356": { "compartment": "compartment_70101", "id": "reaction_10703356", "reactome": "R-PFA-9020271", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024522" ], "products": [ "species_29356", "species_9024463", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10703366": { "compartment": "compartment_70101", "id": "reaction_10703366", "reactome": "R-PFA-9024993", "name": "EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_9025001" ], "products": [ "species_9025011" ], "modifiers": [ [ "species_10694550", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IM75", "PF3D7_1401300" ] }, "reaction_10703358": { "compartment": "compartment_70101", "id": "reaction_10703358", "reactome": "R-PFA-9020273", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024012" ], "products": [ "species_29356", "species_9024815", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10696999": { "compartment": "compartment_7660", "id": "reaction_10696999", "reactome": "R-PFA-5649856", "name": "Oxidative damage to the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689130" ], "products": [ "species_10696997" ], "modifiers": [], "additional_components": [ "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600" ] }, "reaction_10689156": { "compartment": "compartment_7660", "id": "reaction_10689156", "reactome": "R-PFA-110371", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687076", "species_10689152" ], "products": [ "species_10689154" ], "modifiers": [], "additional_components": [ "PF3D7_1304100", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100" ] }, "reaction_10697012": { "compartment": "compartment_7660", "id": "reaction_10697012", "reactome": "R-PFA-5651805", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689154" ], "products": [ "species_10697009" ], "modifiers": [ [ "species_10689154", "catalyst" ] ], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IES4", "PF3D7_1304100", "O97240", "PF3D7_0305600", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100" ] }, "reaction_10689148": { "compartment": "compartment_7660", "id": "reaction_10689148", "reactome": "R-PFA-110368", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689145" ], "products": [ "species_10689141", "species_113541" ], "modifiers": [ [ "species_10689145", "catalyst" ] ], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c" ] }, "reaction_10698360": { "compartment": "compartment_70101", "id": "reaction_10698360", "reactome": "R-PFA-5691512", "name": "APEH hydrolyses NAc-Ser-protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5691496", "species_29356" ], "products": [ "species_6785226", "species_5691517" ], "modifiers": [ [ "species_10698357", "catalyst" ] ], "additional_components": [ "species_5691517", "species_6785226", "PF3D7_0321500" ] }, "reaction_10700732": { "compartment": "compartment_70101", "id": "reaction_10700732", "reactome": "R-PFA-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10700710" ], "products": [ "species_10700717", "species_71285" ], "modifiers": [ [ "species_10700729", "catalyst" ] ], "additional_components": [ "Q8IIC9", "PF3D7_1123400", "species_29438", "O96203", "PF3D7_0212300", "Q8IIC9", "PF3D7_1123400", "species_29438", "O96203", "PF3D7_0212300", "Q8IET4", "PF3D7_1303100", "Q8IM19", "PF3D7_1407500" ] }, "reaction_10703116": { "compartment": "compartment_13231", "id": "reaction_10703116", "reactome": "R-PFA-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703109" ], "products": [ "species_10703107" ], "modifiers": [], "additional_components": [ "PF3D7_0416500", "PF3D7_0416500" ] }, "reaction_10694753": { "compartment": "compartment_70101", "id": "reaction_10694753", "reactome": "R-PFA-2395872", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395868" ], "products": [ "species_111294", "species_2395878" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10694751": { "compartment": "compartment_70101", "id": "reaction_10694751", "reactome": "R-PFA-2395849", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10694748": { "compartment": "compartment_70101", "id": "reaction_10694748", "reactome": "R-PFA-2395818", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395822" ], "products": [ "species_111294", "species_2395855" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10698420": { "compartment": "compartment_5460", "id": "reaction_10698420", "reactome": "R-PFA-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10698407" ], "products": [ "species_113529", "species_29362", "species_10698401" ], "modifiers": [ [ "species_10698417", "catalyst" ] ], "additional_components": [ "Q8II35", "PF3D7_1132900", "CHEBI:50746", "PF3D7_1132900", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10698415": { "compartment": "compartment_5460", "id": "reaction_10698415", "reactome": "R-PFA-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10698405" ], "products": [ "species_5693978", "species_5693984", "species_10698407" ], "modifiers": [ [ "species_10698412", "catalyst" ] ], "additional_components": [ "Q8II35", "PF3D7_1132900", "CHEBI:14949", "Q8II35", "PF3D7_1132900", "CHEBI:50746", "PF3D7_1365500" ] }, "reaction_10697634": { "compartment": "compartment_70101", "id": "reaction_10697634", "reactome": "R-PFA-5688797", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10689705" ], "products": [ "species_10689705", "species_10689703" ], "modifiers": [ [ "species_10697631", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F0", "PF3D7_1226800", "Q8IIP4", "PF3D7_1111900" ] }, "reaction_10697618": { "compartment": "compartment_7660", "id": "reaction_10697618", "reactome": "R-PFA-5688786", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697614", "species_10697609" ], "products": [ "species_10697616" ], "modifiers": [], "additional_components": [ "PF3D7_1226800", "Q8IJS8", "PF3D7_1011700", "Q8IJS8", "PF3D7_1011700", "Q8I5F0", "PF3D7_1226800" ] }, "reaction_10698080": { "compartment": "compartment_70101", "id": "reaction_10698080", "reactome": "R-PFA-5689111", "name": "PARK2 autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698072", "species_10693227" ], "products": [ "species_10697641" ], "modifiers": [ [ "species_10693227", "catalyst" ] ], "additional_components": [ "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_0303800", "PF3D7_0303800", "PF3D7_0303800" ] }, "reaction_10697638": { "compartment": "compartment_7660", "id": "reaction_10697638", "reactome": "R-PFA-5688834", "name": "ATXN3 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697614", "species_10697078" ], "products": [ "species_10697636" ], "modifiers": [], "additional_components": [ "PF3D7_1226800", "C6KT34", "PF3D7_0619400", "C6KT34", "PF3D7_0619400", "Q8I5F0", "PF3D7_1226800" ] }, "reaction_10698075": { "compartment": "compartment_70101", "id": "reaction_10698075", "reactome": "R-PFA-5688837", "name": "ATXN3 deubiquitinates polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10697643" ], "products": [ "species_10697645", "species_10698072" ], "modifiers": [ [ "species_10697643", "catalyst" ] ], "additional_components": [ "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800" ] }, "reaction_10698077": { "compartment": "compartment_70101", "id": "reaction_10698077", "reactome": "R-PFA-5689085", "name": "ATXN3 binds polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697641", "species_10697620" ], "products": [ "species_10697643" ], "modifiers": [], "additional_components": [ "PF3D7_0303800", "PF3D7_1226800", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800" ] }, "reaction_10703328": { "compartment": "compartment_70101", "id": "reaction_10703328", "reactome": "R-PFA-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10696164", "catalyst" ] ], "additional_components": [ "PF3D7_1432100" ] }, "reaction_10699253": { "compartment": "compartment_70101", "id": "reaction_10699253", "reactome": "R-PFA-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29708", "species_29450" ], "modifiers": [ [ "species_10699250", "catalyst" ] ], "additional_components": [ "species_216785", "C0H490", "PF3D7_0406400" ] }, "reaction_10698430": { "compartment": "compartment_70101", "id": "reaction_10698430", "reactome": "R-PFA-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694074", "species_29450" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10698427", "catalyst" ] ], "additional_components": [ "species_216785", "Q8IIM5", "PF3D7_1113700" ] }, "reaction_10696882": { "compartment": "compartment_70101", "id": "reaction_10696882", "reactome": "R-PFA-5618328", "name": "ATAT acetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691147", "species_76183" ], "products": [ "species_10696874", "species_76194" ], "modifiers": [ [ "species_10696879", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29420", "species_29438", "PFI1220w" ] }, "reaction_10696885": { "compartment": "compartment_70101", "id": "reaction_10696885", "reactome": "R-PFA-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696874", "species_76194" ], "products": [ "species_10691147", "species_76183" ], "modifiers": [ [ "species_10696504", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29420", "species_29438", "PF3D7_1008000" ] }, "reaction_10697600": { "compartment": "compartment_17927", "id": "reaction_10697600", "reactome": "R-PFA-5688294", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688282", "species_10697590" ], "products": [ "species_5688281", "species_10689386", "species_5688340" ], "modifiers": [ [ "species_10697597", "catalyst" ] ], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "species_216785", "Q8IE47", "PF13_0152" ] }, "reaction_10689159": { "compartment": "compartment_70101", "id": "reaction_10689159", "reactome": "R-PFA-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10688285", "catalyst" ], [ "species_29372", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IE40", "PF3D7_1327800", "Q8IE67", "PF3D7_1327800" ] }, "reaction_10688292": { "compartment": "compartment_70101", "id": "reaction_10688292", "reactome": "R-PFA-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_113592" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10688289", "catalyst" ] ], "additional_components": [ "Q8IE40", "PF3D7_1327800", "Q8IE67", "PF3D7_1327800" ] }, "reaction_10689586": { "compartment": "compartment_7660", "id": "reaction_10689586", "reactome": "R-PFA-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10688553" ], "modifiers": [], "additional_components": [ "PF3D7_1444300" ] }, "reaction_10693747": { "compartment": "compartment_12045", "id": "reaction_10693747", "reactome": "R-PFA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500596" ], "products": [ "species_1498728", "species_1524021" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693744": { "compartment": "compartment_12045", "id": "reaction_10693744", "reactome": "R-PFA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500594" ], "products": [ "species_1524021", "species_1500596" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693735": { "compartment": "compartment_12045", "id": "reaction_10693735", "reactome": "R-PFA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_1500596" ], "products": [ "species_76116", "species_1500594" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693737": { "compartment": "compartment_12045", "id": "reaction_10693737", "reactome": "R-PFA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728" ], "products": [ "species_76116", "species_1500596" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693759": { "compartment": "compartment_12045", "id": "reaction_10693759", "reactome": "R-PFA-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10688689", "catalyst" ] ], "additional_components": [ "O97295", "PF3D7_0322300" ] }, "reaction_10703201": { "compartment": "compartment_70101", "id": "reaction_10703201", "reactome": "R-PFA-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10703198", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10691072": { "compartment": "compartment_70101", "id": "reaction_10691072", "reactome": "R-PFA-379387", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10691067", "catalyst" ], [ "species_10691070", "inhibitor" ] ], "additional_components": [ "PF3D7_1468300", "Q8IKF4", "PF3D7_1468300" ] }, "reaction_10703636": { "compartment": "compartment_876", "id": "reaction_10703636", "reactome": "R-PFA-9679775", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691067", "species_9679778" ], "products": [ "species_10691070" ], "modifiers": [], "additional_components": [ "PF3D7_1468300", "Q8IKF4", "PF3D7_1468300" ] }, "reaction_10701636": { "compartment": "compartment_20699", "id": "reaction_10701636", "reactome": "R-PFA-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701627" ], "products": [ "species_10701633" ], "modifiers": [ [ "species_10701627", "catalyst" ] ], "additional_components": [ "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420", "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900" ] }, "reaction_10701609": { "compartment": "compartment_20699", "id": "reaction_10701609", "reactome": "R-PFA-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10701605" ], "products": [ "species_10701607" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "Q8IE08", "PF3D7_1332000", "C0H5D3", "PF3D7_1324700", "Q8IKE6", "PF3D7_1469100", "Q8IE08", "PF3D7_1332000", "C0H5D3", "PF3D7_1324700", "Q8IKE6", "PF3D7_1469100", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701629": { "compartment": "compartment_20699", "id": "reaction_10701629", "reactome": "R-PFA-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701617", "species_10694050" ], "products": [ "species_10701627" ], "modifiers": [], "additional_components": [ "Q8IL42", "PF3D7_1442900", "species_29438", "Q7KQL3", "PF10_0203", "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900" ] }, "reaction_10703441": { "compartment": "compartment_70101", "id": "reaction_10703441", "reactome": "R-PFA-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703437", "species_10703409" ], "products": [ "species_10703439" ], "modifiers": [], "additional_components": [ "Q8I599", "PF3D7_1232300", "O96183", "PF3D7_0210000", "Q8I655", "PF3D7_0219400.1", "Q8IL71", "PF3D7_1439800", "Q8IE08", "PF3D7_1332000", "C0H4S2", "PF3D7_0806300", "C0H4W6", "PF3D7_0821800", "O77346", "PF3D7_0312200", "O77346", "PF3D7_0312200", "Q8I599", "PF3D7_1232300", "O96183", "PF3D7_0210000", "Q8I655", "PF3D7_0219400.1", "Q8IL71", "PF3D7_1439800", "Q8IE08", "PF3D7_1332000", "C0H4S2", "PF3D7_0806300", "C0H4W6", "PF3D7_0821800" ] }, "reaction_10694386": { "compartment": "compartment_70616", "id": "reaction_10694386", "reactome": "R-PFA-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694380", "species_10694378", "species_10694353" ], "products": [ "species_10694384" ], "modifiers": [], "additional_components": [ "PF3D7_1368600", "Q8IJ34", "PF3D7_1037300", "Q8ID24", "PF3D7_1368600", "Q8I5W2", "PF3D7_1208600", "PF3D7_0627400", "C6KTB0", "PF3D7_0627400", "Q8IJ34", "PF3D7_1037300", "Q8ID24", "PF3D7_1368600", "Q8I5W2", "PF3D7_1208600" ] }, "reaction_10687270": { "compartment": "compartment_70101", "id": "reaction_10687270", "reactome": "R-PFA-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29448", "species_29472" ], "products": [ "species_111294", "species_29404", "species_29642", "species_76577" ], "modifiers": [ [ "species_10687267", "catalyst" ] ], "additional_components": [ "O77330", "PF3D7_0309500" ] }, "reaction_10687260": { "compartment": "compartment_5460", "id": "reaction_10687260", "reactome": "R-PFA-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113587", "species_113552" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10703196": { "compartment": "compartment_5460", "id": "reaction_10703196", "reactome": "R-PFA-8954468", "name": "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113553" ], "products": [ "species_29374", "species_8954466", "species_113529" ], "modifiers": [ [ "species_10703193", "catalyst" ] ], "additional_components": [ "PF3D7_1437000" ] }, "reaction_10691653": { "compartment": "compartment_70101", "id": "reaction_10691653", "reactome": "R-PFA-429714", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10691634" ], "products": [ "species_29370", "species_10691638" ], "modifiers": [ [ "species_10691650", "catalyst" ] ], "additional_components": [ "PF3D7_0915800", "PF3D7_0915800", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2" ] }, "reaction_10691668": { "compartment": "compartment_20699", "id": "reaction_10691668", "reactome": "R-PFA-429798", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_428270" ], "products": [ "species_429773", "species_429789" ], "modifiers": [ [ "species_10691665", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10691663": { "compartment": "compartment_876", "id": "reaction_10691663", "reactome": "R-PFA-429786", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_429807" ], "products": [ "species_429776", "species_112275" ], "modifiers": [ [ "species_10691660", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10691582": { "compartment": "compartment_70101", "id": "reaction_10691582", "reactome": "R-PFA-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_428163" ], "products": [ "species_428126", "species_76194" ], "modifiers": [ [ "species_10691579", "catalyst" ] ], "additional_components": [ "Q8IM57", "PF3D7_1403700" ] }, "reaction_10703662": { "compartment": "compartment_70101", "id": "reaction_10703662", "reactome": "R-PFA-9695890", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_419305" ], "modifiers": [ [ "species_10703659", "catalyst" ] ], "additional_components": [ "C6KSY4", "PF3D7_0916000", "Q8I2Z2", "PF3D7_0916000" ] }, "reaction_10703229": { "compartment": "compartment_12045", "id": "reaction_10703229", "reactome": "R-PFA-8959462", "name": "SAMD8 transforms PE and CERA to CPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8959490", "species_8959486" ], "products": [ "species_8959463" ], "modifiers": [ [ "species_10703226", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10692484": { "compartment": "compartment_70101", "id": "reaction_10692484", "reactome": "R-PFA-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10692481", "catalyst" ] ], "additional_components": [ "PF3D7_0801800" ] }, "reaction_10692090": { "compartment": "compartment_70101", "id": "reaction_10692090", "reactome": "R-PFA-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10692087", "catalyst" ] ], "additional_components": [ "Q8IJM5", "PF3D7_1017400" ] }, "reaction_10692499": { "compartment": "compartment_70101", "id": "reaction_10692499", "reactome": "R-PFA-548814", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29508", "species_200993" ], "products": [ "species_113528", "species_548812", "species_76194" ], "modifiers": [ [ "species_10692496", "catalyst" ] ], "additional_components": [ "Q8I251", "PF3D7_0109300" ] }, "reaction_10690466": { "compartment": "compartment_70101", "id": "reaction_10690466", "reactome": "R-PFA-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_111294", "species_29356", "species_200993", "species_76577" ], "modifiers": [ [ "species_10690463", "catalyst" ] ], "additional_components": [ "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10692511": { "compartment": "compartment_70101", "id": "reaction_10692511", "reactome": "R-PFA-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_428139", "species_29366" ], "modifiers": [ [ "species_10692508", "catalyst" ] ], "additional_components": [ "Q8II05", "PF3D7_1135900" ] }, "reaction_10697326": { "compartment": "compartment_12045", "id": "reaction_10697326", "reactome": "R-PFA-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_29356", "species_5676634" ], "modifiers": [ [ "species_10697323", "catalyst" ] ], "additional_components": [ "C0H5F1", "PF3D7_1331600" ] }, "reaction_10692492": { "compartment": "compartment_70101", "id": "reaction_10692492", "reactome": "R-PFA-548800", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_29508" ], "products": [ "species_113528", "species_548816", "species_76194" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10698277": { "compartment": "compartment_12045", "id": "reaction_10698277", "reactome": "R-PFA-5690565", "name": "SCD desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10698274", "catalyst" ] ], "additional_components": [ "Q8I0W9", "PF3D7_0511200" ] }, "reaction_10701599": { "compartment": "compartment_12045", "id": "reaction_10701599", "reactome": "R-PFA-8847579", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10701596", "catalyst" ] ], "additional_components": [ "Q8I0W9", "PF3D7_0511200" ] }, "reaction_10698099": { "compartment": "compartment_5460", "id": "reaction_10698099", "reactome": "R-PFA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690540", "species_113521" ], "products": [ "species_29374", "species_5690519" ], "modifiers": [ [ "species_10698096", "catalyst" ] ], "additional_components": [ "species_164991", "CHEBI:61907", "species_174602", "CHEBI:59554", "PF3D7_0217900" ] }, "reaction_10701663": { "compartment": "compartment_70101", "id": "reaction_10701663", "reactome": "R-PFA-8848250", "name": "ACBD6 binds LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164991", "species_10701659" ], "products": [ "species_10701661" ], "modifiers": [], "additional_components": [ "Q8IBL1", "PF3D7_1119000", "Q8IIH7", "PF3D7_1119000", "Q8IBL1", "PF3D7_1119000", "Q8IIH7", "PF3D7_1119000", "species_164991" ] }, "reaction_10694426": { "compartment": "compartment_17957", "id": "reaction_10694426", "reactome": "R-PFA-2046088", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046052", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046051", "species_162743", "species_159751" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10694424": { "compartment": "compartment_12045", "id": "reaction_10694424", "reactome": "R-PFA-2046085", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_2046056", "species_162743" ], "products": [ "species_2046064", "species_2046049", "species_2046062" ], "modifiers": [ [ "species_10694421", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10694430": { "compartment": "compartment_12045", "id": "reaction_10694430", "reactome": "R-PFA-2046098", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_162743", "species_2046044" ], "products": [ "species_2046064", "species_2046049", "species_2046063" ], "modifiers": [ [ "species_10694421", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10694428": { "compartment": "compartment_17957", "id": "reaction_10694428", "reactome": "R-PFA-2046094", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046042", "species_113601" ], "products": [ "species_113519", "species_113564", "species_162743", "species_159751", "species_2046045" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10694555": { "compartment": "compartment_70101", "id": "reaction_10694555", "reactome": "R-PFA-2161999", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142811", "species_29450" ], "products": [ "species_29356", "species_2142678", "species_111745" ], "modifiers": [ [ "species_10694540", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10694543": { "compartment": "compartment_70101", "id": "reaction_10694543", "reactome": "R-PFA-2161959", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_2142790" ], "products": [ "species_29356", "species_2142716", "species_111745" ], "modifiers": [ [ "species_10694540", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10694529": { "compartment": "compartment_70101", "id": "reaction_10694529", "reactome": "R-PFA-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10694534": { "compartment": "compartment_70101", "id": "reaction_10694534", "reactome": "R-PFA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_879629" ], "modifiers": [ [ "species_10694531", "catalyst" ] ], "additional_components": [ "Q8ILQ7", "PF14_0187", "species_29450" ] }, "reaction_10694526": { "compartment": "compartment_70101", "id": "reaction_10694526", "reactome": "R-PFA-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_265283", "species_29364" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690909": { "compartment": "compartment_70101", "id": "reaction_10690909", "reactome": "R-PFA-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10690906", "catalyst" ] ], "additional_components": [ "C0H473", "PF3D7_1453700", "Q8IKU1", "PF3D7_1453700", "A0A144A1J3", "PF3D7_1453700" ] }, "reaction_10693717": { "compartment": "compartment_12045", "id": "reaction_10693717", "reactome": "R-PFA-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10693708", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693711": { "compartment": "compartment_12045", "id": "reaction_10693711", "reactome": "R-PFA-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498740" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10693708", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693714": { "compartment": "compartment_12045", "id": "reaction_10693714", "reactome": "R-PFA-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10693703", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693755": { "compartment": "compartment_12045", "id": "reaction_10693755", "reactome": "R-PFA-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10693752", "catalyst" ] ], "additional_components": [ "PF3D7_1358000" ] }, "reaction_10693706": { "compartment": "compartment_12045", "id": "reaction_10693706", "reactome": "R-PFA-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_975614" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10693703", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693739": { "compartment": "compartment_12045", "id": "reaction_10693739", "reactome": "R-PFA-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498738" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693723": { "compartment": "compartment_12045", "id": "reaction_10693723", "reactome": "R-PFA-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693757": { "compartment": "compartment_12045", "id": "reaction_10693757", "reactome": "R-PFA-1482887", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10693752", "catalyst" ] ], "additional_components": [ "PF3D7_1358000" ] }, "reaction_10693720": { "compartment": "compartment_12045", "id": "reaction_10693720", "reactome": "R-PFA-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498724" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693741": { "compartment": "compartment_12045", "id": "reaction_10693741", "reactome": "R-PFA-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498722" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693923": { "compartment": "compartment_70101", "id": "reaction_10693923", "reactome": "R-PFA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10693920", "catalyst" ] ], "additional_components": [ "Q8IIB7", "PF3D7_1124600", "Q8IM71", "PF3D7_1401800" ] }, "reaction_10693778": { "compartment": "compartment_12045", "id": "reaction_10693778", "reactome": "R-PFA-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_1500581", "species_109395" ], "modifiers": [ [ "species_10693775", "catalyst" ] ], "additional_components": [ "C6KTB9", "PF3D7_0628300.1", "species_29926", "species_1981162" ] }, "reaction_10693889": { "compartment": "compartment_12045", "id": "reaction_10693889", "reactome": "R-PFA-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428686", "species_110614" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10693886", "catalyst" ] ], "additional_components": [ "Q8IDM2", "PF3D7_1347700" ] }, "reaction_10693900": { "compartment": "compartment_12045", "id": "reaction_10693900", "reactome": "R-PFA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10693897", "catalyst" ] ], "additional_components": [ "species_29926", "O77317", "PF3D7_0303200" ] }, "reaction_10693906": { "compartment": "compartment_20699", "id": "reaction_10693906", "reactome": "R-PFA-1483211", "name": "PC:PITPNB is transported from the Golgi membrane to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693849" ], "products": [ "species_10693904" ], "modifiers": [], "additional_components": [ "Q8IDI9", "PF3D7_1351000", "species_194276", "species_194276", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693910": { "compartment": "compartment_12045", "id": "reaction_10693910", "reactome": "R-PFA-1483219", "name": "PC is exchanged with PI by PITPNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_10693904" ], "products": [ "species_426925", "species_10693908" ], "modifiers": [], "additional_components": [ "species_194276", "Q8IDI9", "PF3D7_1351000", "species_1806199", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693925": { "compartment": "compartment_12045", "id": "reaction_10693925", "reactome": "R-PFA-1483229", "name": "PI:PITPNB is transported from the ER membrane to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693908" ], "products": [ "species_10693847" ], "modifiers": [], "additional_components": [ "species_1806199", "Q8IDI9", "PF3D7_1351000", "species_1806199", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10703182": { "compartment": "compartment_984", "id": "reaction_10703182", "reactome": "R-PFA-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2173763" ], "products": [ "species_8954142", "species_8952253" ], "modifiers": [ [ "species_10703179", "catalyst" ] ], "additional_components": [ "PF3D7_0629300" ] }, "reaction_10693795": { "compartment": "compartment_12045", "id": "reaction_10693795", "reactome": "R-PFA-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_426639", "species_109395" ], "modifiers": [ [ "species_10693792", "catalyst" ] ], "additional_components": [ "species_29926", "species_1981162", "C0H5B7", "PF3D7_1315600" ] }, "reaction_10702550": { "compartment": "compartment_70101", "id": "reaction_10702550", "reactome": "R-PFA-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_1602448" ], "products": [ "species_426755", "species_426658" ], "modifiers": [ [ "species_10702547", "catalyst" ] ], "additional_components": [ "Q8IAY0", "PF3D7_0814400", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693869": { "compartment": "compartment_12045", "id": "reaction_10693869", "reactome": "R-PFA-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_111294", "species_426955" ], "modifiers": [ [ "species_10693866", "catalyst" ] ], "additional_components": [ "species_29926", "Q8ILZ6", "PF3D7_1409900" ] }, "reaction_10693859": { "compartment": "compartment_12045", "id": "reaction_10693859", "reactome": "R-PFA-1483089", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_1500581" ], "products": [ "species_1498751", "species_1500646" ], "modifiers": [ [ "species_10693856", "catalyst" ] ], "additional_components": [ "PF3D7_1366800" ] }, "reaction_10693879": { "compartment": "compartment_12045", "id": "reaction_10693879", "reactome": "R-PFA-1483186", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_200736" ], "products": [ "species_264618", "species_1500646" ], "modifiers": [ [ "species_10693876", "catalyst" ] ], "additional_components": [ "PF3D7_1366800" ] }, "reaction_10693824": { "compartment": "compartment_70101", "id": "reaction_10693824", "reactome": "R-PFA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_113592" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10693821", "catalyst" ] ], "additional_components": [ "Q8IIB7", "PF3D7_1124600", "Q8IM71", "PF3D7_1401800" ] }, "reaction_10693840": { "compartment": "compartment_12045", "id": "reaction_10693840", "reactome": "R-PFA-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10693837", "catalyst" ] ], "additional_components": [ "Q8IEE9", "PF3D7_1316600" ] }, "reaction_10693769": { "compartment": "compartment_12045", "id": "reaction_10693769", "reactome": "R-PFA-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_426925", "species_109395" ], "modifiers": [ [ "species_10693766", "catalyst" ] ], "additional_components": [ "C6KTB9", "PF3D7_0628300.1", "species_29926", "species_1981162" ] }, "reaction_10693785": { "compartment": "compartment_20699", "id": "reaction_10693785", "reactome": "R-PFA-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_429785", "species_109395" ], "modifiers": [ [ "species_10693782", "catalyst" ] ], "additional_components": [ "species_29926", "species_1981162", "C6KTB9", "PF3D7_0628300.1" ] }, "reaction_10702281": { "compartment": "compartment_984", "id": "reaction_10702281", "reactome": "R-PFA-8865637", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8865642", "species_74113" ], "products": [ "species_8865629", "species_83910" ], "modifiers": [ [ "species_10702278", "catalyst" ] ], "additional_components": [ "PF3D7_0529200" ] }, "reaction_10693874": { "compartment": "compartment_70616", "id": "reaction_10693874", "reactome": "R-PFA-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524101", "species_110577" ], "products": [ "species_159450", "species_1524064" ], "modifiers": [ [ "species_10693871", "catalyst" ] ], "additional_components": [ "PF3D7_1409900" ] }, "reaction_10694115": { "compartment": "compartment_876", "id": "reaction_10694115", "reactome": "R-PFA-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_1806224", "species_29370" ], "modifiers": [ [ "species_10694015", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694018": { "compartment": "compartment_876", "id": "reaction_10694018", "reactome": "R-PFA-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_1806240", "species_29370" ], "modifiers": [ [ "species_10694015", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694081": { "compartment": "compartment_876", "id": "reaction_10694081", "reactome": "R-PFA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10694078", "catalyst" ] ], "additional_components": [ "A0A143ZZC6", "PF3D7_1111600", "Q8IC15", "PF3D7_0705500" ] }, "reaction_10693990": { "compartment": "compartment_876", "id": "reaction_10693990", "reactome": "R-PFA-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10693987", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694086": { "compartment": "compartment_876", "id": "reaction_10694086", "reactome": "R-PFA-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10694040", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694091": { "compartment": "compartment_876", "id": "reaction_10694091", "reactome": "R-PFA-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10694088", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694120": { "compartment": "compartment_876", "id": "reaction_10694120", "reactome": "R-PFA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10694117", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694129": { "compartment": "compartment_876", "id": "reaction_10694129", "reactome": "R-PFA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10694126", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694132": { "compartment": "compartment_876", "id": "reaction_10694132", "reactome": "R-PFA-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10694088", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694043": { "compartment": "compartment_876", "id": "reaction_10694043", "reactome": "R-PFA-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10694040", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10702655": { "compartment": "compartment_20699", "id": "reaction_10702655", "reactome": "R-PFA-8870499", "name": "PLEKHA3,8 bind PI4P, ARF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690955", "species_10702651", "species_1806217" ], "products": [ "species_10702653" ], "modifiers": [], "additional_components": [ "PF10_0203", "Q8I2Z4", "PF3D7_0915800", "species_392417", "Q8I2Z4", "PF3D7_0915800", "Q7KQL3", "PF10_0203" ] }, "reaction_10694109": { "compartment": "compartment_12045", "id": "reaction_10694109", "reactome": "R-PFA-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806234" ], "products": [ "species_29372", "species_426639" ], "modifiers": [ [ "species_10694106", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694083": { "compartment": "compartment_20699", "id": "reaction_10694083", "reactome": "R-PFA-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10694112": { "compartment": "compartment_20699", "id": "reaction_10694112", "reactome": "R-PFA-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_29372", "species_1524146" ], "modifiers": [ [ "species_10694101", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694055": { "compartment": "compartment_20699", "id": "reaction_10694055", "reactome": "R-PFA-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10694052", "catalyst" ] ], "additional_components": [ "species_29438", "Q7KQL3", "PF10_0203", "Q8I406", "PF3D7_0509800" ] }, "reaction_10694023": { "compartment": "compartment_20699", "id": "reaction_10694023", "reactome": "R-PFA-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10694020", "catalyst" ] ], "additional_components": [ "PF3D7_0705500" ] }, "reaction_10694104": { "compartment": "compartment_20699", "id": "reaction_10694104", "reactome": "R-PFA-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806159" ], "products": [ "species_29372", "species_1524146" ], "modifiers": [ [ "species_10694101", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694124": { "compartment": "compartment_20699", "id": "reaction_10694124", "reactome": "R-PFA-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694122", "species_10694050" ], "products": [ "species_10694052" ], "modifiers": [], "additional_components": [ "PF3D7_0509800", "species_29438", "Q7KQL3", "PF10_0203", "species_29438", "Q7KQL3", "PF10_0203", "Q8I406", "PF3D7_0509800" ] }, "reaction_10694093": { "compartment": "compartment_172574", "id": "reaction_10694093", "reactome": "R-PFA-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_1806198", "species_29370" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10688692": { "compartment": "compartment_70101", "id": "reaction_10688692", "reactome": "R-PFA-75900", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_76103" ], "products": [ "species_549167", "species_76194" ], "modifiers": [ [ "species_10688689", "catalyst" ] ], "additional_components": [ "O97295", "PF3D7_0322300" ] }, "reaction_10688586": { "compartment": "compartment_70101", "id": "reaction_10688586", "reactome": "R-PFA-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76116" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10688583", "catalyst" ] ], "additional_components": [ "Q8IDI4", "PF3D7_1351600" ] }, "reaction_10688682": { "compartment": "compartment_70101", "id": "reaction_10688682", "reactome": "R-PFA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76108", "species_29356" ], "products": [ "species_29372", "species_76103" ], "modifiers": [ [ "species_10688679", "catalyst" ] ], "additional_components": [ "O77317", "PF3D7_0303200" ] }, "reaction_10688368": { "compartment": "compartment_5460", "id": "reaction_10688368", "reactome": "R-PFA-73916", "name": "2 acetyl-CoA <=> acetoacetyl-CoA + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559" ], "products": [ "species_29374", "species_73871" ], "modifiers": [ [ "species_10687343", "catalyst" ] ], "additional_components": [ "Q8IKW7", "PF3D7_1450900" ] }, "reaction_10696583": { "compartment": "compartment_876", "id": "reaction_10696583", "reactome": "R-PFA-5340320", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5340315" ], "products": [ "species_5340299" ], "modifiers": [ [ "species_10696580", "catalyst" ] ], "additional_components": [ "PF3D7_0915800" ] }, "reaction_10693976": { "compartment": "compartment_876", "id": "reaction_10693976", "reactome": "R-PFA-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10693973", "catalyst" ] ], "additional_components": [ "Q8I537", "PF3D7_1238600", "species_29926" ] }, "reaction_10702983": { "compartment": "compartment_7660", "id": "reaction_10702983", "reactome": "R-PFA-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702972", "species_77087" ], "products": [ "species_77502", "species_10702975" ], "modifiers": [ [ "species_10702980", "catalyst" ] ], "additional_components": [ "PF3D7_0818900", "PF3D7_0818900", "PF3D7_1142700" ] }, "reaction_10703019": { "compartment": "compartment_70101", "id": "reaction_10703019", "reactome": "R-PFA-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10689442" ], "products": [ "species_71285", "species_10703011" ], "modifiers": [ [ "species_10703016", "catalyst" ] ], "additional_components": [ "PF3D7_1357000", "PF3D7_1357000", "PF3D7_0916600" ] }, "reaction_10703002": { "compartment": "compartment_70101", "id": "reaction_10703002", "reactome": "R-PFA-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696509", "species_71284" ], "products": [ "species_10702997", "species_71285" ], "modifiers": [ [ "species_10702999", "catalyst" ] ], "additional_components": [ "PF3D7_0619400", "PF3D7_0619400", "PF3D7_1142700" ] }, "reaction_10695844": { "compartment": "compartment_7660", "id": "reaction_10695844", "reactome": "R-PFA-4568914", "name": "SUMOylation of BLM with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695835", "species_10695825" ], "products": [ "species_10695841", "species_10694930" ], "modifiers": [ [ "species_10695835", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_0918600", "PF3D7_0918600", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695934": { "compartment": "compartment_7660", "id": "reaction_10695934", "reactome": "R-PFA-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695924" ], "products": [ "species_10695932", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1432600", "Q8ILD6", "PF3D7_1432600", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695805": { "compartment": "compartment_7660", "id": "reaction_10695805", "reactome": "R-PFA-4551724", "name": "PIAS4 SUMOylates HERC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695789", "species_10694938" ], "products": [ "species_10695802", "species_10694930" ], "modifiers": [ [ "species_10695666", "catalyst" ] ], "additional_components": [ "Q8IDD6", "PF3D7_1356600", "Q8I5L0", "PF3D7_1356600", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I444", "PF3D7_0505800", "Q8I5L0", "PF3D7_1356600", "Q8IDD6", "PF3D7_1356600", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695984": { "compartment": "compartment_7660", "id": "reaction_10695984", "reactome": "R-PFA-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695974" ], "products": [ "species_10695982", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0925700", "Q8I444", "PF3D7_0505800", "Q7K6A1", "PF3D7_0925700", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695911": { "compartment": "compartment_7660", "id": "reaction_10695911", "reactome": "R-PFA-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10689874" ], "products": [ "species_10695909", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1105000", "Q8IIV2", "PF3D7_1105000", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695894": { "compartment": "compartment_7660", "id": "reaction_10695894", "reactome": "R-PFA-4570485", "name": "SUMOylation of Histone H4 with SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695833", "species_10689874" ], "products": [ "species_10694930", "species_10695891" ], "modifiers": [ [ "species_10695833", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1105000", "PF3D7_0915100", "PF3D7_1105000", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695957": { "compartment": "compartment_7660", "id": "reaction_10695957", "reactome": "R-PFA-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10693554" ], "products": [ "species_10694930", "species_10695955" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0925700", "PF3D7_0915100", "Q7K6A1", "PF3D7_0925700", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695888": { "compartment": "compartment_7660", "id": "reaction_10695888", "reactome": "R-PFA-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695877" ], "products": [ "species_10695886", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1008800", "Q8I444", "PF3D7_0505800", "Q8IJV7", "PF3D7_1008800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695901": { "compartment": "compartment_7660", "id": "reaction_10695901", "reactome": "R-PFA-4570489", "name": "SUMOylation of NOP58 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695653", "species_10695877" ], "products": [ "species_10695898", "species_10694930" ], "modifiers": [ [ "species_10695653", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1008800", "PF3D7_1008800", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695715": { "compartment": "compartment_7660", "id": "reaction_10695715", "reactome": "R-PFA-4085992", "name": "SUMOylation of DAXX with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695018" ], "products": [ "species_10695713", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0807600", "Q8I444", "PF3D7_0505800", "C0H4S8", "PF3D7_0807600", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695633": { "compartment": "compartment_7660", "id": "reaction_10695633", "reactome": "R-PFA-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695614", "species_10694938" ], "products": [ "species_10695630", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I459", "PF3D7_1445900", "Q8IAR1", "PF3D7_1445900", "Q8IL13", "PF3D7_1445900", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I444", "PF3D7_0505800", "Q8IAR1", "PF3D7_1445900", "Q8I459", "PF3D7_1445900", "Q8IL13", "PF3D7_1445900", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695664": { "compartment": "compartment_7660", "id": "reaction_10695664", "reactome": "R-PFA-3900194", "name": "PIAS1 SUMOylates DDX5 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695653", "species_10695635" ], "products": [ "species_10695656", "species_10694930" ], "modifiers": [ [ "species_10695661", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1445900", "PF3D7_1445900", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695694": { "compartment": "compartment_7660", "id": "reaction_10695694", "reactome": "R-PFA-4085331", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695681" ], "products": [ "species_10695689", "species_10694930" ], "modifiers": [ [ "species_10695691", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0627500", "C6KTB1", "PF3D7_0627500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695645": { "compartment": "compartment_7660", "id": "reaction_10695645", "reactome": "R-PFA-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695635" ], "products": [ "species_10695643", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1445900", "Q8I444", "PF3D7_0505800", "Q8IL13", "PF3D7_1445900", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10690843": { "compartment": "compartment_70101", "id": "reaction_10690843", "reactome": "R-PFA-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690808", "species_70106", "species_29368", "species_73473" ], "products": [ "species_29356", "species_10690833", "species_29360" ], "modifiers": [ [ "species_10690840", "catalyst" ] ], "additional_components": [ "Q8I603", "PF3D7_1204300", "Q8I603", "PF3D7_1204300", "Q8I701", "PF3D7_1302600", "species_71067" ] }, "reaction_10690826": { "compartment": "compartment_70101", "id": "reaction_10690826", "reactome": "R-PFA-204647", "name": "DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690814", "species_204635", "species_29360" ], "products": [ "species_70106", "species_10690808", "species_204628", "species_73473" ], "modifiers": [ [ "species_10690821", "catalyst" ] ], "additional_components": [ "Q8I603", "PF3D7_1204300", "Q8I603", "PF3D7_1204300", "Q8ILW8", "PF3D7_1412600" ] }, "reaction_10696630": { "compartment": "compartment_70101", "id": "reaction_10696630", "reactome": "R-PFA-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696605", "species_71284" ], "products": [ "species_353106", "species_10696592" ], "modifiers": [ [ "species_10696622", "catalyst" ], [ "species_10696628", "catalyst" ] ], "additional_components": [ "PF3D7_1451100", "PF3D7_1451100", "Q8ILV7", "PF3D7_1413800", "Q8ILG9", "PF3D7_1429500", "Q8I5N0", "PF3D7_1217800", "PF3D7_0502800" ] }, "reaction_10696603": { "compartment": "compartment_70101", "id": "reaction_10696603", "reactome": "R-PFA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10696592" ], "products": [ "species_71285", "species_10696595" ], "modifiers": [ [ "species_10696600", "catalyst" ] ], "additional_components": [ "PF3D7_1451100", "PF3D7_1451100", "PF3D7_1009000" ] }, "reaction_10699358": { "compartment": "compartment_12045", "id": "reaction_10699358", "reactome": "R-PFA-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_71285", "species_6788758" ], "modifiers": [ [ "species_10699355", "catalyst" ] ], "additional_components": [ "Q8I555", "PF3D7_1236800", "species_216785" ] }, "reaction_10689522": { "compartment": "compartment_12045", "id": "reaction_10689522", "reactome": "R-PFA-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855663" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10689519", "catalyst" ] ], "additional_components": [ "PF3D7_1247300" ] }, "reaction_10689506": { "compartment": "compartment_12045", "id": "reaction_10689506", "reactome": "R-PFA-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855667" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10689503", "catalyst" ] ], "additional_components": [ "PF3D7_1341600" ] }, "reaction_10689514": { "compartment": "compartment_70101", "id": "reaction_10689514", "reactome": "R-PFA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_8855661", "species_29416" ], "modifiers": [ [ "species_10689511", "catalyst" ] ], "additional_components": [ "PF3D7_0624700" ] }, "reaction_10689498": { "compartment": "compartment_17957", "id": "reaction_10689498", "reactome": "R-PFA-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_8855666", "species_76194" ], "modifiers": [ [ "species_10689495", "catalyst" ] ], "additional_components": [ "PF3D7_0615300" ] }, "reaction_10692115": { "compartment": "compartment_12045", "id": "reaction_10692115", "reactome": "R-PFA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449222" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10692112", "catalyst" ] ], "additional_components": [ "Q8IAQ4", "PF3D7_0806400", "O96196", "PF3D7_0211600" ] }, "reaction_10692070": { "compartment": "compartment_12045", "id": "reaction_10692070", "reactome": "R-PFA-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449299" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10692067", "catalyst" ] ], "additional_components": [ "PF3D7_0321200" ] }, "reaction_10695754": { "compartment": "compartment_12045", "id": "reaction_10695754", "reactome": "R-PFA-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419981", "species_29364" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10695751", "catalyst" ] ], "additional_components": [ "PF3D7_1455900" ] }, "reaction_10692078": { "compartment": "compartment_12045", "id": "reaction_10692078", "reactome": "R-PFA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_449221" ], "products": [ "species_110094", "species_449299" ], "modifiers": [ [ "species_10692075", "catalyst" ] ], "additional_components": [ "PF3D7_0109850" ] }, "reaction_10699345": { "compartment": "compartment_70101", "id": "reaction_10699345", "reactome": "R-PFA-6787632", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860" ], "products": [ "species_29356", "species_6787618" ], "modifiers": [ [ "species_10699342", "catalyst" ] ], "additional_components": [ "PF3D7_0813800" ] }, "reaction_10699348": { "compartment": "compartment_70101", "id": "reaction_10699348", "reactome": "R-PFA-6787642", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6787646", "species_29364" ], "products": [ "species_742368", "species_29366" ], "modifiers": [ [ "species_10699334", "catalyst" ] ], "additional_components": [ "A0A143ZXB3", "PF3D7_1014000" ] }, "reaction_10699337": { "compartment": "compartment_70101", "id": "reaction_10699337", "reactome": "R-PFA-6787623", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787618" ], "products": [ "species_6787646" ], "modifiers": [ [ "species_10699334", "catalyst" ] ], "additional_components": [ "A0A143ZXB3", "PF3D7_1014000" ] }, "reaction_10692100": { "compartment": "compartment_70101", "id": "reaction_10692100", "reactome": "R-PFA-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_532204" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10692097", "catalyst" ] ], "additional_components": [ "Q8IDQ3", "PF3D7_1343600" ] }, "reaction_10692127": { "compartment": "compartment_70101", "id": "reaction_10692127", "reactome": "R-PFA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512", "species_29472" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10692124", "catalyst" ] ], "additional_components": [ "Q8IJF3", "PF3D7_1025100" ] }, "reaction_10692062": { "compartment": "compartment_70101", "id": "reaction_10692062", "reactome": "R-PFA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10692059", "catalyst" ] ], "additional_components": [ "PF3D7_1130000" ] }, "reaction_10701400": { "compartment": "compartment_20699", "id": "reaction_10701400", "reactome": "R-PFA-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10701396" ], "products": [ "species_10701398" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IKE6", "PF3D7_1469100", "C0H5D3", "PF3D7_1324700", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IKE6", "PF3D7_1469100", "C0H5D3", "PF3D7_1324700", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701278": { "compartment": "compartment_6791047", "id": "reaction_10701278", "reactome": "R-PFA-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701225", "species_10701274" ], "products": [ "species_10701276" ], "modifiers": [], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203" ] }, "reaction_10701228": { "compartment": "compartment_6791047", "id": "reaction_10701228", "reactome": "R-PFA-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10701223" ], "products": [ "species_29370", "species_10701225" ], "modifiers": [ [ "species_10701223", "catalyst" ] ], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10692738": { "compartment": "compartment_17963", "id": "reaction_10692738", "reactome": "R-PFA-914017", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10692672" ], "products": [ "species_205687", "species_10692736" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10692704": { "compartment": "compartment_17963", "id": "reaction_10692704", "reactome": "R-PFA-914008", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10692672" ], "products": [ "species_10692702", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10692694": { "compartment": "compartment_17963", "id": "reaction_10692694", "reactome": "R-PFA-914006", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10692672" ], "products": [ "species_10692692", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500" ] }, "reaction_10692684": { "compartment": "compartment_17963", "id": "reaction_10692684", "reactome": "R-PFA-914005", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10692672" ], "products": [ "species_10692682", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10696147": { "compartment": "compartment_12045", "id": "reaction_10696147", "reactome": "R-PFA-5173192", "name": "POFUT2 transfers fucose to TSR domain-containing proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696139" ], "products": [ "species_10696118" ], "modifiers": [ [ "species_10696144", "catalyst" ] ], "additional_components": [ "O97267", "PF3D7_0315200", "O97267", "PF3D7_0315200", "PF3D7_0909200" ] }, "reaction_10698145": { "compartment": "compartment_70101", "id": "reaction_10698145", "reactome": "R-PFA-5690159", "name": "USP21 deubiquitinates RIPK1,DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698138" ], "products": [ "species_10698142", "species_10698072" ], "modifiers": [ [ "species_10698138", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8IDK6", "PF3D7_1349300", "Q8IL78", "PF3D7_1439100", "Q8ILU9", "PF3D7_1414700", "Q8IL78", "PF3D7_1439100", "Q8IDK6", "PF3D7_1349300", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ILU9", "PF3D7_1414700", "Q8IDK6", "PF3D7_1349300", "Q8IL78", "PF3D7_1439100" ] }, "reaction_10698720": { "compartment": "compartment_7660", "id": "reaction_10698720", "reactome": "R-PFA-5696960", "name": "USP49 deubiquitinates H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698715" ], "products": [ "species_10698717", "species_10686649" ], "modifiers": [ [ "species_10698715", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8ILU9", "PF3D7_1414700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ILU9", "PF3D7_1414700" ] }, "reaction_10698089": { "compartment": "compartment_70101", "id": "reaction_10698089", "reactome": "R-PFA-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698085", "species_10697200" ], "products": [ "species_10698087" ], "modifiers": [], "additional_components": [ "PF3D7_0527200", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "Q8I3J3", "PF3D7_0527200" ] }, "reaction_10698681": { "compartment": "compartment_70101", "id": "reaction_10698681", "reactome": "R-PFA-5696627", "name": "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698678" ], "products": [ "species_10689710", "species_10689705" ], "modifiers": [ [ "species_10698678", "catalyst" ] ], "additional_components": [ "Q8IDK6", "PF3D7_1349300", "O97313", "PFC1020c", "PF3D7_1349300", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8IDK6", "PF3D7_1349300", "O97313", "PFC1020c" ] }, "reaction_10698126": { "compartment": "compartment_7660", "id": "reaction_10698126", "reactome": "R-PFA-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698121" ], "products": [ "species_10686649", "species_10698123" ], "modifiers": [ [ "species_10698121", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ILU9", "PF3D7_1414700", "Q8ILU9", "PF3D7_1414700" ] }, "reaction_10699197": { "compartment": "compartment_7660", "id": "reaction_10699197", "reactome": "R-PFA-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698740" ], "products": [ "species_10698744", "species_10699194" ], "modifiers": [ [ "species_10698740", "catalyst" ] ], "additional_components": [ "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700", "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700" ] }, "reaction_10698352": { "compartment": "compartment_70101", "id": "reaction_10698352", "reactome": "R-PFA-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689705" ], "products": [ "species_10689703" ], "modifiers": [ [ "species_10686745", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "PF3D7_1368100" ] }, "reaction_10699265": { "compartment": "compartment_7660", "id": "reaction_10699265", "reactome": "R-PFA-6783238", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699261", "species_10699259" ], "products": [ "species_10699263" ], "modifiers": [], "additional_components": [ "PF3D7_1203900", "Q8ILN4", "PF3D7_1421600", "Q8ILN4", "PF3D7_1421600", "Q8I607", "PF3D7_1203900" ] }, "reaction_10702033": { "compartment": "compartment_70101", "id": "reaction_10702033", "reactome": "R-PFA-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701967", "species_113592", "species_10686740" ], "products": [ "species_111294", "species_10701969" ], "modifiers": [ [ "species_10701967", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702039": { "compartment": "compartment_70101", "id": "reaction_10702039", "reactome": "R-PFA-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693374", "species_113592", "species_10686740" ], "products": [ "species_111294", "species_10701971" ], "modifiers": [ [ "species_10693374", "catalyst" ] ], "additional_components": [ "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "PF3D7_1333200" ] }, "reaction_10701991": { "compartment": "compartment_70101", "id": "reaction_10701991", "reactome": "R-PFA-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701965", "species_10701969" ], "products": [ "species_10701989", "species_10701971" ], "modifiers": [], "additional_components": [ "Q8I2U3", "PF3D7_0921000.1", "Q8IJ70", "PF3D7_1033900", "Q8IDD9", "PF3D7_1356300", "Q8I607", "PF3D7_1203900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8I2U3", "PF3D7_0921000.1", "Q8IDD9", "PF3D7_1356300", "Q8I607", "PF3D7_1203900", "Q8IJ70", "PF3D7_1033900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10701895": { "compartment": "compartment_70101", "id": "reaction_10701895", "reactome": "R-PFA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701881", "species_10701879" ], "products": [ "species_10701883", "species_10701893" ], "modifiers": [], "additional_components": [ "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8IDZ6", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDZ6", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10702070": { "compartment": "compartment_70101", "id": "reaction_10702070", "reactome": "R-PFA-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686680" ], "products": [ "species_10686680", "species_10687728" ], "modifiers": [ [ "species_10698177", "catalyst" ] ], "additional_components": [ "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1460400" ] }, "reaction_10702036": { "compartment": "compartment_70101", "id": "reaction_10702036", "reactome": "R-PFA-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701971" ], "products": [ "species_10701967", "species_76577" ], "modifiers": [ [ "species_10701971", "catalyst" ] ], "additional_components": [ "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10701963": { "compartment": "compartment_7660", "id": "reaction_10701963", "reactome": "R-PFA-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686649", "species_10701897" ], "products": [ "species_10701961", "species_113541" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702074": { "compartment": "compartment_70101", "id": "reaction_10702074", "reactome": "R-PFA-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702072" ], "products": [ "species_10686680", "species_10688129" ], "modifiers": [ [ "species_10698177", "catalyst" ] ], "additional_components": [ "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1460400" ] }, "reaction_10702041": { "compartment": "compartment_7660", "id": "reaction_10702041", "reactome": "R-PFA-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701961" ], "products": [ "species_164121", "species_10701993" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500" ] }, "reaction_10702030": { "compartment": "compartment_7660", "id": "reaction_10702030", "reactome": "R-PFA-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686649", "species_10701993" ], "products": [ "species_10701995", "species_113541" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702028": { "compartment": "compartment_7660", "id": "reaction_10702028", "reactome": "R-PFA-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701995", "species_10702007" ], "products": [ "species_10701961", "species_10702026" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "O77397", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8ILW5", "PF3D7_1412900.1", "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8I607", "PF3D7_1203900", "O77397", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8ILW5", "PF3D7_1412900.1", "Q8I2U3", "PF3D7_0921000.1" ] }, "reaction_10702374": { "compartment": "compartment_70101", "id": "reaction_10702374", "reactome": "R-PFA-8865774", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_10691147" ], "products": [ "species_29372", "species_10702344", "species_29370" ], "modifiers": [ [ "species_10702371", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29438", "species_29420", "Q8IJU8", "PF3D7_1147200", "Q8IHP8", "PF3D7_1147200" ] }, "reaction_10688265": { "compartment": "compartment_70101", "id": "reaction_10688265", "reactome": "R-PFA-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111628", "species_70106" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10688271": { "compartment": "compartment_70101", "id": "reaction_10688271", "reactome": "R-PFA-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111627", "species_113592", "species_29472" ], "products": [ "species_111647", "species_29372", "species_29404", "species_29370" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10688255": { "compartment": "compartment_70101", "id": "reaction_10688255", "reactome": "R-PFA-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_76630" ], "products": [ "species_76632", "species_76633" ], "modifiers": [ [ "species_10688252", "catalyst" ] ], "additional_components": [ "species_73524", "Q08210", "PFF0160c" ] }, "reaction_10688268": { "compartment": "compartment_70101", "id": "reaction_10688268", "reactome": "R-PFA-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111647", "species_29448" ], "products": [ "species_111628", "species_29372" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10702131": { "compartment": "compartment_17938", "id": "reaction_10702131", "reactome": "R-PFA-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702126", "species_29356" ], "products": [ "species_29372", "species_10702128" ], "modifiers": [ [ "species_10702126", "catalyst" ] ], "additional_components": [ "species_29438", "C0H516", "PF3D7_0903200", "species_29420", "C0H516", "PF3D7_0903200", "species_29438", "C0H516", "PF3D7_0903200" ] }, "reaction_10702146": { "compartment": "compartment_5683628", "id": "reaction_10702146", "reactome": "R-PFA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702141", "species_29356" ], "products": [ "species_29372", "species_10702143" ], "modifiers": [ [ "species_10702141", "catalyst" ] ], "additional_components": [ "Q8IDL8", "PF3D7_1348100", "species_29438", "Q8IDL8", "PF3D7_1348100", "species_29420", "Q8IDL8", "PF3D7_1348100", "species_29438" ] }, "reaction_10702113": { "compartment": "compartment_17938", "id": "reaction_10702113", "reactome": "R-PFA-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10702102" ], "products": [ "species_29372", "species_10702104" ], "modifiers": [ [ "species_10702102", "catalyst" ], [ "species_10702111", "catalyst" ] ], "additional_components": [ "species_29438", "C0H516", "PF3D7_0903200", "C0H516", "PF3D7_0903200", "species_29420", "species_29438", "C0H516", "PF3D7_0903200", "Q8I379", "PF3D7_1114200", "Q8IIL9", "PF3D7_1114200" ] }, "reaction_10702850": { "compartment": "compartment_17938", "id": "reaction_10702850", "reactome": "R-PFA-8877451", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702823" ], "products": [ "species_10702685", "species_10702831", "species_29420" ], "modifiers": [ [ "species_10702847", "catalyst" ] ], "additional_components": [ "C0H516", "PF3D7_0903200", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "C0H516", "PF3D7_0903200", "species_29438", "Q8IIT1", "PF3D7_1107200", "Q8IDH2", "PF3D7_1352800" ] }, "reaction_10702761": { "compartment": "compartment_171062", "id": "reaction_10702761", "reactome": "R-PFA-8875320", "name": "RAB5 GEFs exchange GTP for GDP on RAB5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702687" ], "products": [ "species_10702685", "species_29420", "species_10702705" ], "modifiers": [ [ "species_10702758", "catalyst" ] ], "additional_components": [ "O96193", "PF3D7_0211200", "Q8I274", "PF3D7_0211200", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "species_29438", "Q8ILY5", "PF3D7_1411000.2", "A0A144A1B7", "PF3D7_1411000.2", "Q8IAZ5", "PF3D7_1411000.2" ] }, "reaction_10702910": { "compartment": "compartment_13946", "id": "reaction_10702910", "reactome": "R-PFA-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702872" ], "products": [ "species_10702685", "species_29420", "species_10702886" ], "modifiers": [ [ "species_10702907", "catalyst" ] ], "additional_components": [ "A0A5K1K8H7", "PF3D7_0513800", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I560", "PF3D7_1236300", "Q8I481", "PF3D7_0501900", "Q8I451", "PF3D7_0505100" ] }, "reaction_10689388": { "compartment": "compartment_17906", "id": "reaction_10689388", "reactome": "R-PFA-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689386" ], "products": [ "species_10689380" ], "modifiers": [], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8I6T6", "PF3D7_1404100" ] }, "reaction_10693609": { "compartment": "compartment_5460", "id": "reaction_10693609", "reactome": "R-PFA-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693598", "species_379721", "species_10693585" ], "products": [ "species_10693606", "species_379697", "species_10693600" ], "modifiers": [ [ "species_10693585", "catalyst" ], [ "species_10693598", "catalyst" ] ], "additional_components": [ "CHEBI:33738", "Q8I5R0", "PF3D7_1214600", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067", "Q8I5R0", "PF3D7_1214600", "CHEBI:33737", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "CHEBI:33739", "Q8IBI5", "PF3D7_0727200", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067", "CHEBI:33738", "Q8I5R0", "PF3D7_1214600" ] }, "reaction_10693614": { "compartment": "compartment_5460", "id": "reaction_10693614", "reactome": "R-PFA-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693612", "species_113531" ], "products": [ "species_10693585" ], "modifiers": [], "additional_components": [ "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067" ] }, "reaction_10693558": { "compartment": "compartment_70101", "id": "reaction_10693558", "reactome": "R-PFA-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_8942986", "species_983036" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10703040": { "compartment": "compartment_70101", "id": "reaction_10703040", "reactome": "R-PFA-8940641", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032" ], "products": [ "species_8955634" ], "modifiers": [ [ "species_10703037", "catalyst" ] ], "additional_components": [ "PF3D7_1005700" ] }, "reaction_10693397": { "compartment": "compartment_70101", "id": "reaction_10693397", "reactome": "R-PFA-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693343", "species_10693394" ], "products": [ "species_10693392", "species_10693345" ], "modifiers": [ [ "species_10693343", "catalyst" ] ], "additional_components": [ "Q8IAW2", "PF3D7_0812600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600" ] }, "reaction_10693403": { "compartment": "compartment_70101", "id": "reaction_10693403", "reactome": "R-PFA-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693351", "species_10693345" ], "products": [ "species_111294", "species_10693343", "species_10693368", "species_76577" ], "modifiers": [ [ "species_10693351", "catalyst" ] ], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10693354": { "compartment": "compartment_70101", "id": "reaction_10693354", "reactome": "R-PFA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693347" ], "products": [ "species_111294", "species_10693343", "species_10693351", "species_76577" ], "modifiers": [ [ "species_10693271", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693370": { "compartment": "compartment_70101", "id": "reaction_10693370", "reactome": "R-PFA-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693368" ], "products": [ "species_983123", "species_10693271" ], "modifiers": [], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693400": { "compartment": "compartment_70101", "id": "reaction_10693400", "reactome": "R-PFA-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10686740", "species_29926", "species_10693392" ], "products": [ "species_111294", "species_29926", "species_10693394", "species_76577" ], "modifiers": [ [ "species_10693392", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10693405": { "compartment": "compartment_70101", "id": "reaction_10693405", "reactome": "R-PFA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983035", "species_10693271", "species_10693345" ], "products": [ "species_10693347" ], "modifiers": [], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693372": { "compartment": "compartment_70101", "id": "reaction_10693372", "reactome": "R-PFA-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_10686740", "species_983032", "species_8942986", "species_983036" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10693366": { "compartment": "compartment_17957", "id": "reaction_10693366", "reactome": "R-PFA-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_983032" ], "products": [ "species_29372", "species_29370", "species_983034" ], "modifiers": [ [ "species_10693363", "catalyst" ] ], "additional_components": [ "Q8IHR3", "PF3D7_1145500" ] }, "reaction_10690798": { "compartment": "compartment_12045", "id": "reaction_10690798", "reactome": "R-PFA-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690794", "species_10690709" ], "products": [ "species_10690796" ], "modifiers": [], "additional_components": [ "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29438", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10694518": { "compartment": "compartment_161320", "id": "reaction_10694518", "reactome": "R-PFA-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10694515", "catalyst" ] ], "additional_components": [ "Q8I6Z5", "PF3D7_1323500", "Q8IIL0", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800" ] }, "reaction_10698337": { "compartment": "compartment_7660", "id": "reaction_10698337", "reactome": "R-PFA-5691004", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698333", "species_10695924", "species_10695861" ], "products": [ "species_10698335" ], "modifiers": [], "additional_components": [ "Q8IJS8", "PF3D7_1011700", "PF3D7_1432600", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8ILD6", "PF3D7_1432600", "Q8IJS8", "PF3D7_1011700" ] }, "reaction_10688851": { "compartment": "compartment_7660", "id": "reaction_10688851", "reactome": "R-PFA-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688847", "species_10688842" ], "products": [ "species_10688849" ], "modifiers": [], "additional_components": [ "PF3D7_1368800", "PF3D7_0203300", "O96136", "PF3D7_0203300", "Q8ID22", "PF3D7_1368800" ] }, "reaction_10688768": { "compartment": "compartment_7660", "id": "reaction_10688768", "reactome": "R-PFA-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688760" ], "products": [ "species_10688765" ], "modifiers": [ [ "species_10688760", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578" ] }, "reaction_10688774": { "compartment": "compartment_7660", "id": "reaction_10688774", "reactome": "R-PFA-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687534", "species_10687529" ], "products": [ "species_10687536" ], "modifiers": [], "additional_components": [ "PF3D7_1369500", "PF3D7_0415500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500" ] }, "reaction_10688725": { "compartment": "compartment_7660", "id": "reaction_10688725", "reactome": "R-PFA-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688723" ], "products": [ "species_10688723" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688756": { "compartment": "compartment_7660", "id": "reaction_10688756", "reactome": "R-PFA-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688749" ], "products": [ "species_113550", "species_10688753" ], "modifiers": [ [ "species_10688749", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688772": { "compartment": "compartment_7660", "id": "reaction_10688772", "reactome": "R-PFA-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688765" ], "products": [ "species_10688770" ], "modifiers": [], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688763": { "compartment": "compartment_7660", "id": "reaction_10688763", "reactome": "R-PFA-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10688753" ], "products": [ "species_10688760", "species_111349" ], "modifiers": [ [ "species_10688753", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688747": { "compartment": "compartment_7660", "id": "reaction_10688747", "reactome": "R-PFA-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688743", "species_10688737", "species_10688723" ], "products": [ "species_10688745" ], "modifiers": [], "additional_components": [ "PF3D7_0610900", "PF3D7_0705000", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688776": { "compartment": "compartment_7660", "id": "reaction_10688776", "reactome": "R-PFA-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687606", "species_10687536" ], "products": [ "species_10687608" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10688751": { "compartment": "compartment_7660", "id": "reaction_10688751", "reactome": "R-PFA-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688745", "species_72084", "species_29428" ], "products": [ "species_10688749" ], "modifiers": [], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10695347": { "compartment": "compartment_70101", "id": "reaction_10695347", "reactome": "R-PFA-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695322", "species_10695339", "species_10695331" ], "products": [ "species_10695318", "species_10695345" ], "modifiers": [], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "PF14_0324", "Q8IL88", "PF3D7_1437900", "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_113582", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10695362": { "compartment": "compartment_70101", "id": "reaction_10695362", "reactome": "R-PFA-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695358", "species_10695360" ], "products": [ "species_10695320" ], "modifiers": [], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10696814": { "compartment": "compartment_70101", "id": "reaction_10696814", "reactome": "R-PFA-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10695345" ], "products": [ "species_10696808" ], "modifiers": [], "additional_components": [ "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_29358", "species_113582", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10695325": { "compartment": "compartment_70101", "id": "reaction_10695325", "reactome": "R-PFA-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695320" ], "products": [ "species_29372", "species_10695322" ], "modifiers": [ [ "species_10695320", "catalyst" ], [ "species_10695318", "catalyst" ] ], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900" ] }, "reaction_10703669": { "compartment": "compartment_70101", "id": "reaction_10703669", "reactome": "R-PFA-9712274", "name": "NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703008", "species_9714134" ], "products": [ "species_10703667" ], "modifiers": [], "additional_components": [ "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10695268": { "compartment": "compartment_17957", "id": "reaction_10695268", "reactome": "R-PFA-3341296", "name": "GPX7,8 catalyze peroxidation of P4HB (PDI)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695241", "species_3341383" ], "products": [ "species_113519", "species_10695252" ], "modifiers": [ [ "species_10695265", "catalyst" ] ], "additional_components": [ "Q8I2V9", "PF3D7_1472600", "Q8IKB2", "PF3D7_1472600", "C0H4Y6", "PF3D7_1472600", "Q8IKB2", "PF3D7_1472600", "Q8I2V9", "PF3D7_1472600", "C0H4Y6", "PF3D7_1472600", "Q8IIC3", "PF3D7_1124000", "Q8I5T2", "PF3D7_1212000" ] }, "reaction_10695227": { "compartment": "compartment_70616", "id": "reaction_10695227", "reactome": "R-PFA-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10689563" ], "products": [ "species_10689561", "species_189461" ], "modifiers": [], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "CHEBI:38574", "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "CHEBI:38573" ] }, "reaction_10698668": { "compartment": "compartment_5460", "id": "reaction_10698668", "reactome": "R-PFA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696199", "species_113521" ], "products": [ "species_5696194", "species_113573" ], "modifiers": [ [ "species_10698665", "catalyst" ] ], "additional_components": [ "PF3D7_0520600" ] }, "reaction_10690238": { "compartment": "compartment_70101", "id": "reaction_10690238", "reactome": "R-PFA-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10690235", "catalyst" ] ], "additional_components": [ "species_29926", "C0H556", "PF3D7_0924300" ] }, "reaction_10690256": { "compartment": "compartment_70101", "id": "reaction_10690256", "reactome": "R-PFA-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73524" ], "products": [ "species_111294", "species_29386" ], "modifiers": [ [ "species_10690253", "catalyst" ] ], "additional_components": [ "PF3D7_1015000" ] }, "reaction_10690266": { "compartment": "compartment_70101", "id": "reaction_10690266", "reactome": "R-PFA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10690263", "catalyst" ] ], "additional_components": [ "Q8IDB3", "PF3D7_1359100", "species_29926" ] }, "reaction_10690356": { "compartment": "compartment_876", "id": "reaction_10690356", "reactome": "R-PFA-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10690353", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10690379": { "compartment": "compartment_70101", "id": "reaction_10690379", "reactome": "R-PFA-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690365", "species_1497805" ], "products": [ "species_10690363", "species_198816" ], "modifiers": [ [ "species_10690365", "catalyst" ] ], "additional_components": [ "species_917877", "Q8I599", "PF3D7_1232300", "CHEBI:36144", "Q8I599", "PF3D7_1232300", "species_917877", "Q8I599", "PF3D7_1232300" ] }, "reaction_10690376": { "compartment": "compartment_70101", "id": "reaction_10690376", "reactome": "R-PFA-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10690363", "species_73473" ], "products": [ "species_10690365", "species_29360" ], "modifiers": [ [ "species_10690373", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "Q8I599", "PF3D7_1232300", "species_917877", "Q8I599", "PF3D7_1232300", "Q8ID33", "PF3D7_1367500", "species_29386" ] }, "reaction_10694965": { "compartment": "compartment_70101", "id": "reaction_10694965", "reactome": "R-PFA-3000238", "name": "LMBRD1 transports lysosomal Cbl to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3000239" ], "products": [ "species_3000241" ], "modifiers": [ [ "species_10694962", "catalyst" ] ], "additional_components": [ "PF3D7_1338000" ] }, "reaction_10693012": { "compartment": "compartment_70101", "id": "reaction_10693012", "reactome": "R-PFA-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10692996" ], "products": [ "species_10693001", "species_29432" ], "modifiers": [ [ "species_10693009", "catalyst" ] ], "additional_components": [ "Q8ID54", "PF3D7_1365400", "species_216785", "species_216785", "Q8ID54", "PF3D7_1365400", "Q8IBI5", "PF3D7_0727200" ] }, "reaction_10690435": { "compartment": "compartment_70616", "id": "reaction_10690435", "reactome": "R-PFA-200720", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671" ], "products": [ "species_111355" ], "modifiers": [ [ "species_10690425", "catalyst" ] ], "additional_components": [ "PF3D7_0811100" ] }, "reaction_10700995": { "compartment": "compartment_70101", "id": "reaction_10700995", "reactome": "R-PFA-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_29372", "species_70106", "species_29370", "species_200640" ], "modifiers": [ [ "species_10700992", "catalyst" ] ], "additional_components": [ "PF3D7_1245000" ] }, "reaction_10690433": { "compartment": "compartment_70101", "id": "reaction_10690433", "reactome": "R-PFA-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690417": { "compartment": "compartment_70101", "id": "reaction_10690417", "reactome": "R-PFA-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10698693": { "compartment": "compartment_5460", "id": "reaction_10698693", "reactome": "R-PFA-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801451", "species_200671", "species_113593" ], "products": [ "species_113548", "species_113581", "species_5389850" ], "modifiers": [ [ "species_10698690", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690437": { "compartment": "compartment_70101", "id": "reaction_10690437", "reactome": "R-PFA-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_200640" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10700997": { "compartment": "compartment_5460", "id": "reaction_10700997", "reactome": "R-PFA-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_5389850" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10698690", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690420": { "compartment": "compartment_70101", "id": "reaction_10690420", "reactome": "R-PFA-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_29356", "species_200640" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10700987": { "compartment": "compartment_5460", "id": "reaction_10700987", "reactome": "R-PFA-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_5693984" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10700984", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10701000": { "compartment": "compartment_5460", "id": "reaction_10701000", "reactome": "R-PFA-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10700984", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690431": { "compartment": "compartment_70101", "id": "reaction_10690431", "reactome": "R-PFA-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29372", "species_29370", "species_111353" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10693026": { "compartment": "compartment_70101", "id": "reaction_10693026", "reactome": "R-PFA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965053" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10693024": { "compartment": "compartment_70101", "id": "reaction_10693024", "reactome": "R-PFA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10693028": { "compartment": "compartment_70101", "id": "reaction_10693028", "reactome": "R-PFA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965131" ], "products": [ "species_29390", "species_29370" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10688410": { "compartment": "compartment_70101", "id": "reaction_10688410", "reactome": "R-PFA-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83962", "species_500244" ], "products": [ "species_29372", "species_500430" ], "modifiers": [ [ "species_10688407", "catalyst" ] ], "additional_components": [ "CHEBI:28542", "species_112016", "CHEBI:16450", "CHEBI:16704", "Q8I3X4", "PF3D7_0513300" ] }, "reaction_10694172": { "compartment": "compartment_70101", "id": "reaction_10694172", "reactome": "R-PFA-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694168", "species_10694166" ], "products": [ "species_10694170" ], "modifiers": [], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IKX4", "PF3D7_1450100", "C6KT56", "PF3D7_0621900", "Q8I613", "PF3D7_1203200", "Q8II00", "PF3D7_1136400", "Q8I5P4", "PF3D7_1216300", "C0H4Q0", "PF3D7_0729000", "Q8IKX4", "PF3D7_1450100", "C6KT56", "PF3D7_0621900", "Q8I613", "PF3D7_1203200", "Q8II00", "PF3D7_1136400", "Q8I5P4", "PF3D7_1216300", "C0H4Q0", "PF3D7_0729000", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200" ] }, "reaction_10696497": { "compartment": "compartment_70101", "id": "reaction_10696497", "reactome": "R-PFA-5263614", "name": "MeSeOH is reduced to MeSeH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357663", "species_70106", "species_29364" ], "products": [ "species_29356", "species_29366", "species_5357669" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "P61076", "PFI1170c", "species_29386" ] }, "reaction_10696500": { "compartment": "compartment_70101", "id": "reaction_10696500", "reactome": "R-PFA-5263616", "name": "MeSeO2H is reduced to MeSeOH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357694", "species_70106", "species_29364" ], "products": [ "species_5357663", "species_29356", "species_29366" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "P61076", "PFI1170c", "species_29386" ] }, "reaction_10696797": { "compartment": "compartment_5263232", "id": "reaction_10696797", "reactome": "R-PFA-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696793", "species_30389" ], "products": [ "species_10696795", "species_10696785" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800", "Q7KQK0", "PF3D7_1223100", "Q7KQK0", "PF3D7_1223100", "species_30389", "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800" ] }, "reaction_10687497": { "compartment": "compartment_70101", "id": "reaction_10687497", "reactome": "R-PFA-71732", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10687494", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "O77392", "PF3D7_0316300.2", "C0H477", "PF3D7_0316300.2" ] }, "reaction_10692143": { "compartment": "compartment_5460", "id": "reaction_10692143", "reactome": "R-PFA-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159450", "species_113521" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10692140", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "C0H477", "PF3D7_0316300.2", "O77392", "PF3D7_0316300.2" ] }, "reaction_10696800": { "compartment": "compartment_70101", "id": "reaction_10696800", "reactome": "R-PFA-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10696902": { "compartment": "compartment_70616", "id": "reaction_10696902", "reactome": "R-PFA-5623643", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623644", "species_5623648", "species_163953" ], "products": [ "species_5623650", "species_5623649" ], "modifiers": [ [ "species_10696899", "catalyst" ] ], "additional_components": [ "PF3D7_0626100" ] }, "reaction_10690305": { "compartment": "compartment_7660", "id": "reaction_10690305", "reactome": "R-PFA-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690301" ], "products": [ "species_10690303" ], "modifiers": [], "additional_components": [ "PF3D7_1113900", "PF3D7_1113900" ] }, "reaction_10701024": { "compartment": "compartment_70101", "id": "reaction_10701024", "reactome": "R-PFA-6803890", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701020" ], "products": [ "species_10701022" ], "modifiers": [], "additional_components": [ "C0H4V6", "PF3D7_1362100", "A0A5K1K948", "PF3D7_1362100", "C0H4V6", "PF3D7_1362100", "A0A5K1K948", "PF3D7_1362100" ] }, "reaction_10689362": { "compartment": "compartment_7660", "id": "reaction_10689362", "reactome": "R-PFA-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689307", "species_10689316" ], "products": [ "species_10689318" ], "modifiers": [], "additional_components": [ "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000" ] }, "reaction_10689339": { "compartment": "compartment_7660", "id": "reaction_10689339", "reactome": "R-PFA-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687608", "species_10688666", "species_10689314" ], "products": [ "species_10688666", "species_10689316" ], "modifiers": [ [ "species_10689314", "catalyst" ] ], "additional_components": [ "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "PF3D7_1012700", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "PF3D7_1012700" ] }, "reaction_10694275": { "compartment": "compartment_7660", "id": "reaction_10694275", "reactome": "R-PFA-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694195": { "compartment": "compartment_7660", "id": "reaction_10694195", "reactome": "R-PFA-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694341": { "compartment": "compartment_7660", "id": "reaction_10694341", "reactome": "R-PFA-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023922" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694335": { "compartment": "compartment_7660", "id": "reaction_10694335", "reactome": "R-PFA-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023940" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694254": { "compartment": "compartment_7660", "id": "reaction_10694254", "reactome": "R-PFA-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694213": { "compartment": "compartment_70101", "id": "reaction_10694213", "reactome": "R-PFA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10694210", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694251": { "compartment": "compartment_70101", "id": "reaction_10694251", "reactome": "R-PFA-1855178", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629756" ], "products": [ "species_1629731" ], "modifiers": [ [ "species_10694248", "catalyst" ] ], "additional_components": [ "species_113526", "Q8I3Y8", "PF3D7_0511800" ] }, "reaction_10694329": { "compartment": "compartment_876", "id": "reaction_10694329", "reactome": "R-PFA-1855222", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10694281", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694338": { "compartment": "compartment_70101", "id": "reaction_10694338", "reactome": "R-PFA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_1629765", "species_29370" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694208": { "compartment": "compartment_70101", "id": "reaction_10694208", "reactome": "R-PFA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694272": { "compartment": "compartment_70101", "id": "reaction_10694272", "reactome": "R-PFA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694298": { "compartment": "compartment_70101", "id": "reaction_10694298", "reactome": "R-PFA-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10694263", "catalyst" ] ], "additional_components": [ "Q8ILG1", "PF3D7_1430300" ] }, "reaction_10694266": { "compartment": "compartment_70101", "id": "reaction_10694266", "reactome": "R-PFA-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10694263", "catalyst" ] ], "additional_components": [ "Q8ILG1", "PF3D7_1430300" ] }, "reaction_10694269": { "compartment": "compartment_70101", "id": "reaction_10694269", "reactome": "R-PFA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694332": { "compartment": "compartment_70101", "id": "reaction_10694332", "reactome": "R-PFA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694241": { "compartment": "compartment_70101", "id": "reaction_10694241", "reactome": "R-PFA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10694238", "catalyst" ] ], "additional_components": [ "species_74016", "Q8IJR0", "PF3D7_1013500" ] }, "reaction_10694288": { "compartment": "compartment_876", "id": "reaction_10694288", "reactome": "R-PFA-1855213", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10694285", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694295": { "compartment": "compartment_12045", "id": "reaction_10694295", "reactome": "R-PFA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10694292", "catalyst" ] ], "additional_components": [ "Q8IJR0", "PF3D7_1013500", "species_74016" ] }, "reaction_10694326": { "compartment": "compartment_876", "id": "reaction_10694326", "reactome": "R-PFA-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10694323", "catalyst" ] ], "additional_components": [ "species_74016", "Q8IJR0", "PF3D7_1013500" ] }, "reaction_10694301": { "compartment": "compartment_70101", "id": "reaction_10694301", "reactome": "R-PFA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10694210", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10701576": { "compartment": "compartment_70101", "id": "reaction_10701576", "reactome": "R-PFA-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701570" ], "products": [ "species_29372", "species_10701574" ], "modifiers": [], "additional_components": [ "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "species_29358", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "Q8I5C4", "PF3D7_1229500", "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "species_113582", "Q8I5C4", "PF3D7_1229500" ] }, "reaction_10701580": { "compartment": "compartment_70101", "id": "reaction_10701580", "reactome": "R-PFA-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701578", "species_113592" ], "products": [ "species_29370", "species_10701570" ], "modifiers": [], "additional_components": [ "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "species_113582", "Q8I5C4", "PF3D7_1229500", "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "species_29358", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "Q8I5C4", "PF3D7_1229500" ] }, "reaction_10701763": { "compartment": "compartment_17963", "id": "reaction_10701763", "reactome": "R-PFA-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_8851233" ], "products": [ "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10701757", "catalyst" ] ], "additional_components": [ "species_110577", "species_29494", "species_29438", "species_30187", "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701760": { "compartment": "compartment_17963", "id": "reaction_10701760", "reactome": "R-PFA-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851226", "species_8851227" ], "modifiers": [ [ "species_10701757", "catalyst" ] ], "additional_components": [ "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_113578", "species_109366", "species_109402", "species_109395", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701792": { "compartment": "compartment_984", "id": "reaction_10701792", "reactome": "R-PFA-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701750": { "compartment": "compartment_984", "id": "reaction_10701750", "reactome": "R-PFA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701747", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701733": { "compartment": "compartment_984", "id": "reaction_10701733", "reactome": "R-PFA-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701730", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701780": { "compartment": "compartment_984", "id": "reaction_10701780", "reactome": "R-PFA-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8851462" ], "products": [ "species_109277", "species_8851461" ], "modifiers": [ [ "species_10701777", "catalyst" ] ], "additional_components": [ "CHEBI:17808", "species_205687", "species_29420", "species_110094", "species_109402", "species_29602", "species_109395", "species_113578", "species_29926", "species_74016", "Q8ILE7", "PF3D7_1431800" ] }, "reaction_10701787": { "compartment": "compartment_528865", "id": "reaction_10701787", "reactome": "R-PFA-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851517", "species_8851509" ], "products": [ "species_8851513", "species_8851518" ], "modifiers": [ [ "species_10701784", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110577", "species_110094", "species_205687", "species_29420", "Q8IE96", "PF3D7_1322000", "species_74016" ] }, "reaction_10701753": { "compartment": "compartment_984", "id": "reaction_10701753", "reactome": "R-PFA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701747", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701736": { "compartment": "compartment_876", "id": "reaction_10701736", "reactome": "R-PFA-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701730", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701743": { "compartment": "compartment_984", "id": "reaction_10701743", "reactome": "R-PFA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936166", "species_109276" ], "products": [ "species_109277", "species_8851092" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_2509836", "species_29438", "species_29494", "species_110577", "species_29358", "CHEBI:17808", "species_113582", "species_205687", "species_29420", "species_110094", "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701773": { "compartment": "compartment_984", "id": "reaction_10701773", "reactome": "R-PFA-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936165" ], "products": [ "species_8851369", "species_109277" ], "modifiers": [ [ "species_10701770", "catalyst" ] ], "additional_components": [ "species_113582", "species_205687", "species_29420", "species_110094", "species_109402", "species_109395", "species_113578", "species_76577", "species_29926", "species_74016", "Q8ILE7", "PF3D7_1431800" ] }, "reaction_10701789": { "compartment": "compartment_984", "id": "reaction_10701789", "reactome": "R-PFA-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10696804": { "compartment": "compartment_876", "id": "reaction_10696804", "reactome": "R-PFA-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691235", "species_10691203" ], "products": [ "species_10696802" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "PF3D7_1348800", "A0A5K1K8L6", "PF3D7_1348800", "C0H553", "PF3D7_0923200" ] }, "reaction_10688530": { "compartment": "compartment_17940", "id": "reaction_10688530", "reactome": "R-PFA-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10688527", "catalyst" ] ], "additional_components": [ "C0H4P0", "PF3D7_0721900", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8IDF7", "PF3D7_1354400", "Q8IKJ0", "PF3D7_1464700", "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10692234": { "compartment": "compartment_70101", "id": "reaction_10692234", "reactome": "R-PFA-450466", "name": "AUF1:mRNA complex is destroyed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692232" ], "products": [], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8I2Y5", "PF3D7_0916700", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10692221": { "compartment": "compartment_70101", "id": "reaction_10692221", "reactome": "R-PFA-450434", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450444", "species_10692215" ], "products": [ "species_10692219" ], "modifiers": [], "additional_components": [ "Q8I2Y5", "PF3D7_0916700", "Q8I2Y5", "PF3D7_0916700" ] }, "reaction_10701160": { "compartment": "compartment_7660", "id": "reaction_10701160", "reactome": "R-PFA-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701156", "species_10689351" ], "products": [ "species_10701158" ], "modifiers": [], "additional_components": [ "Q8IDR5", "PF3D7_1342400", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400", "Q8IDR5", "PF3D7_1342400", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200" ] }, "reaction_10700957": { "compartment": "compartment_876", "id": "reaction_10700957", "reactome": "R-PFA-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700953", "species_10700948" ], "products": [ "species_10700955" ], "modifiers": [], "additional_components": [ "PF3D7_0602500", "PF3D7_1442500", "Q8IL46", "PF3D7_1442500", "C6KSM5", "PF3D7_0602500" ] }, "reaction_10701682": { "compartment": "compartment_70101", "id": "reaction_10701682", "reactome": "R-PFA-8848829", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692652", "species_10686740" ], "products": [ "species_10701679" ], "modifiers": [ [ "species_10692652", "catalyst" ] ], "additional_components": [ "PF3D7_1208800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1208800", "PF3D7_1208800" ] }, "reaction_10694665": { "compartment": "compartment_70101", "id": "reaction_10694665", "reactome": "R-PFA-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_179856" ], "products": [ "species_10694663" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "species_179856", "Q8IIE7", "PF3D7_1121900" ] }, "reaction_10692274": { "compartment": "compartment_5460", "id": "reaction_10692274", "reactome": "R-PFA-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374064", "species_113521" ], "products": [ "species_374061", "species_113585" ], "modifiers": [ [ "species_10692271", "catalyst" ] ], "additional_components": [ "species_1981162", "Q8I384", "PF3D7_0906500" ] }, "reaction_10687249": { "compartment": "compartment_70101", "id": "reaction_10687249", "reactome": "R-PFA-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29468" ], "products": [ "species_29514", "species_29498" ], "modifiers": [ [ "species_10687246", "catalyst" ] ], "additional_components": [ "species_1981162", "Q8I384", "PF3D7_0906500" ] }, "reaction_10690983": { "compartment": "compartment_70101", "id": "reaction_10690983", "reactome": "R-PFA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_204635", "species_353106" ], "modifiers": [ [ "species_10690980", "catalyst" ] ], "additional_components": [ "PF3D7_1129000" ] }, "reaction_10687304": { "compartment": "compartment_70101", "id": "reaction_10687304", "reactome": "R-PFA-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10687301", "catalyst" ] ], "additional_components": [ "PF3D7_1033100" ] }, "reaction_10690975": { "compartment": "compartment_70101", "id": "reaction_10690975", "reactome": "R-PFA-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_353555", "species_76194" ], "modifiers": [ [ "species_10690970", "catalyst" ] ], "additional_components": [ "PF3D7_0713900" ] }, "reaction_10690973": { "compartment": "compartment_70101", "id": "reaction_10690973", "reactome": "R-PFA-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10690970", "catalyst" ] ], "additional_components": [ "PF3D7_0713900" ] }, "reaction_10687283": { "compartment": "compartment_5460", "id": "reaction_10687283", "reactome": "R-PFA-70654", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113585" ], "products": [ "species_31339", "species_113552" ], "modifiers": [ [ "species_10687280", "catalyst" ] ], "additional_components": [ "Q6LFH8", "PFF0435w" ] }, "reaction_10699301": { "compartment": "compartment_70101", "id": "reaction_10699301", "reactome": "R-PFA-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_35305", "species_29364" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10699298", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10699294": { "compartment": "compartment_5460", "id": "reaction_10699294", "reactome": "R-PFA-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10699291", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10687293": { "compartment": "compartment_5460", "id": "reaction_10687293", "reactome": "R-PFA-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10687290", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10690407": { "compartment": "compartment_876", "id": "reaction_10690407", "reactome": "R-PFA-200396", "name": "Creatine transport across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200381", "species_74113" ], "products": [ "species_29916", "species_83910" ], "modifiers": [ [ "species_10690404", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10699868": { "compartment": "compartment_70101", "id": "reaction_10699868", "reactome": "R-PFA-6797956", "name": "SLC44A1 transports Cho from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618" ], "products": [ "species_6798162" ], "modifiers": [ [ "species_10699865", "catalyst" ] ], "additional_components": [ "PF3D7_1431900" ] }, "reaction_10687346": { "compartment": "compartment_5460", "id": "reaction_10687346", "reactome": "R-PFA-70844", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_70836" ], "products": [ "species_70843", "species_113559" ], "modifiers": [ [ "species_10687343", "catalyst" ] ], "additional_components": [ "Q8IKW7", "PF3D7_1450900" ] }, "reaction_10698395": { "compartment": "compartment_5460", "id": "reaction_10698395", "reactome": "R-PFA-5693153", "name": "PPM1K dephosphorylates p-BCKDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698385", "species_113521" ], "products": [ "species_113548", "species_10687333" ], "modifiers": [ [ "species_10698392", "catalyst" ] ], "additional_components": [ "O97227", "PF3D7_0303700", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I0X1", "PF3D7_0504600", "Q8I5A0", "PF3D7_1232200", "species_29386", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I5A0", "PF3D7_1232200", "species_29386", "C0H4T6", "PF3D7_0810300", "species_1981162" ] }, "reaction_10687354": { "compartment": "compartment_5460", "id": "reaction_10687354", "reactome": "R-PFA-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10687351", "catalyst" ] ], "additional_components": [ "PF3D7_1240000" ] }, "reaction_10687336": { "compartment": "compartment_5460", "id": "reaction_10687336", "reactome": "R-PFA-70713", "name": "BCKDH transfers CoA group from CoA-SH to BCAAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_508181" ], "products": [ "species_29362", "species_508261", "species_29376" ], "modifiers": [ [ "species_10687333", "catalyst" ] ], "additional_components": [ "CHEBI:16530", "CHEBI:28654", "CHEBI:17865", "CHEBI:15479", "CHEBI:15487", "CHEBI:15477", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10699863": { "compartment": "compartment_5460", "id": "reaction_10699863", "reactome": "R-PFA-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699853", "species_6793610", "species_2162265" ], "products": [ "species_379705", "species_6793613", "species_10698401" ], "modifiers": [ [ "species_10699860", "catalyst" ] ], "additional_components": [ "PF3D7_1132900", "PF3D7_1132900", "Q8IDQ0", "MAL13P1.220", "CHEBI:49883" ] }, "reaction_10699850": { "compartment": "compartment_5460", "id": "reaction_10699850", "reactome": "R-PFA-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699840", "species_10698401" ], "products": [ "species_10699842", "species_10698403" ], "modifiers": [ [ "species_10699847", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386", "Q8I0X1", "PF3D7_0504600", "Q8IEJ6", "PF3D7_1312600", "O97227", "PF3D7_0303700", "PF3D7_1132900", "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "Q8IEJ6", "PF3D7_1312600", "PF3D7_1132900", "PF3D7_1314600" ] }, "reaction_10699304": { "compartment": "compartment_5460", "id": "reaction_10699304", "reactome": "R-PFA-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784236", "species_113587" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10687396": { "compartment": "compartment_5460", "id": "reaction_10687396", "reactome": "R-PFA-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29362", "species_29376" ], "modifiers": [ [ "species_10687393", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10687406": { "compartment": "compartment_70101", "id": "reaction_10687406", "reactome": "R-PFA-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10687403", "catalyst" ] ], "additional_components": [ "C6S3E6", "PF3D7_1108300" ] }, "reaction_10690627": { "compartment": "compartment_876", "id": "reaction_10690627", "reactome": "R-PFA-203680", "name": "eNOS:NOSIP translocation from caveolae to intracellular compartments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690591" ], "products": [ "species_10690625" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "C0H4E6", "PF3D7_0518000", "C0H4E6", "PF3D7_0518000", "C0H553", "PF3D7_0923200", "species_917877", "species_216785", "species_73524", "species_29386", "species_29870" ] }, "reaction_10690593": { "compartment": "compartment_70101", "id": "reaction_10690593", "reactome": "R-PFA-203553", "name": "eNOS binds NOSIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690589", "species_10690485" ], "products": [ "species_10690591" ], "modifiers": [], "additional_components": [ "PF3D7_0518000", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "C0H4E6", "PF3D7_0518000" ] }, "reaction_10696674": { "compartment": "compartment_7660", "id": "reaction_10696674", "reactome": "R-PFA-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_5358610" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10687076", "catalyst" ] ], "additional_components": [ "PF3D7_1304100" ] }, "reaction_10696707": { "compartment": "compartment_7660", "id": "reaction_10696707", "reactome": "R-PFA-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10696653", "species_10696648" ], "products": [ "species_10696668" ], "modifiers": [], "additional_components": [ "PF3D7_0505500", "PF3D7_1427500", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582" ] }, "reaction_10696672": { "compartment": "compartment_7660", "id": "reaction_10696672", "reactome": "R-PFA-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696668", "species_5358514" ], "products": [ "species_10696670" ], "modifiers": [], "additional_components": [ "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582" ] }, "reaction_10696709": { "compartment": "compartment_7660", "id": "reaction_10696709", "reactome": "R-PFA-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696636", "species_10696641" ], "products": [ "species_10696643" ], "modifiers": [], "additional_components": [ "PF3D7_1117800", "PF3D7_0726300", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800" ] }, "reaction_10696661": { "compartment": "compartment_7660", "id": "reaction_10696661", "reactome": "R-PFA-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687014", "species_10696657", "species_10696643" ], "products": [ "species_10696659" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696683": { "compartment": "compartment_7660", "id": "reaction_10696683", "reactome": "R-PFA-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696679", "species_10696663" ], "products": [ "species_10696681" ], "modifiers": [], "additional_components": [ "PF3D7_0725000", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "Q8IBK1", "PF3D7_0725000", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696666": { "compartment": "compartment_7660", "id": "reaction_10696666", "reactome": "R-PFA-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696659" ], "products": [ "species_10696663" ], "modifiers": [ [ "species_10696659", "catalyst" ] ], "additional_components": [ "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696685": { "compartment": "compartment_7660", "id": "reaction_10696685", "reactome": "R-PFA-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10696670" ], "products": [ "species_113582", "species_10696657" ], "modifiers": [], "additional_components": [ "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10690965": { "compartment": "compartment_70101", "id": "reaction_10690965", "reactome": "R-PFA-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10690953" ], "products": [ "species_10690957", "species_29420" ], "modifiers": [ [ "species_10690962", "catalyst" ] ], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q7KQL3", "PF10_0203", "species_29438", "PF3D7_1442900" ] }, "reaction_10696403": { "compartment": "compartment_171907", "id": "reaction_10696403", "reactome": "R-PFA-5229111", "name": "AP4 transports APP from trans-Golgi network to endosome lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696386" ], "products": [ "species_10696400" ], "modifiers": [ [ "species_10696386", "catalyst" ] ], "additional_components": [ "Q8IIH2", "PF3D7_1119500", "Q8IBF8", "PF3D7_0730200", "Q8IFN5", "PF3D7_0423100", "Q8I3A8", "PF3D7_0904100", "Q8IFN5", "PF3D7_0423100", "Q8IIH2", "PF3D7_1119500", "Q8I3A8", "PF3D7_0904100", "Q8IBF8", "PF3D7_0730200", "Q8IIH2", "PF3D7_1119500", "Q8IBF8", "PF3D7_0730200", "Q8IFN5", "PF3D7_0423100", "Q8I3A8", "PF3D7_0904100" ] }, "reaction_10689478": { "compartment": "compartment_70101", "id": "reaction_10689478", "reactome": "R-PFA-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10689469", "species_10689473" ], "products": [ "species_10689444", "species_10689475" ], "modifiers": [ [ "species_10689469", "catalyst" ] ], "additional_components": [ "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300", "Q8I0P6", "PF3D7_1357000", "species_29420", "Q8I0P6", "PF3D7_1357000", "species_29438", "species_29420", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300" ] }, "reaction_10689471": { "compartment": "compartment_70101", "id": "reaction_10689471", "reactome": "R-PFA-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689467", "species_10689462", "species_10689456" ], "products": [ "species_10689469" ], "modifiers": [], "additional_components": [ "PF3D7_1338300", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300" ] }, "reaction_10689366": { "compartment": "compartment_7660", "id": "reaction_10689366", "reactome": "R-PFA-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688727" ], "products": [ "species_10688727" ], "modifiers": [], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10688732": { "compartment": "compartment_7660", "id": "reaction_10688732", "reactome": "R-PFA-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10688727" ], "products": [ "species_113582", "species_10688729" ], "modifiers": [ [ "species_10688727", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10689360": { "compartment": "compartment_7660", "id": "reaction_10689360", "reactome": "R-PFA-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689305", "species_10688743" ], "products": [ "species_10689307" ], "modifiers": [], "additional_components": [ "PF3D7_1030000", "PF3D7_0610900", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000" ] }, "reaction_10689364": { "compartment": "compartment_7660", "id": "reaction_10689364", "reactome": "R-PFA-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689336" ], "products": [ "species_10689336" ], "modifiers": [], "additional_components": [ "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "C6KSQ9", "PF3D7_0606100", "Q9U0K9", "PF3D7_0407700", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "C6KSQ9", "PF3D7_0606100", "Q9U0K9", "PF3D7_0407700" ] }, "reaction_10689353": { "compartment": "compartment_7660", "id": "reaction_10689353", "reactome": "R-PFA-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689349", "species_10689344" ], "products": [ "species_10689351" ], "modifiers": [], "additional_components": [ "PF3D7_0517400", "PF3D7_1441400", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400" ] }, "reaction_10689133": { "compartment": "compartment_7660", "id": "reaction_10689133", "reactome": "R-PFA-110359", "name": "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689116" ], "products": [ "species_10689130" ], "modifiers": [ [ "species_10689116", "catalyst" ] ], "additional_components": [ "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600" ] }, "reaction_10697443": { "compartment": "compartment_70101", "id": "reaction_10697443", "reactome": "R-PFA-5682377", "name": "LC3 de-lipidation by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697357" ], "products": [ "species_5681998", "species_10697347" ], "modifiers": [ [ "species_10697404", "catalyst" ] ], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "species_1500581", "Q8IJK2", "PF3D7_1019900", "Q8ILS3", "PF3D7_1417300" ] }, "reaction_10697409": { "compartment": "compartment_70101", "id": "reaction_10697409", "reactome": "R-PFA-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697363", "species_10697347" ], "products": [ "species_10697374" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697457": { "compartment": "compartment_5683628", "id": "reaction_10697457", "reactome": "R-PFA-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697357" ], "products": [ "species_10697455" ], "modifiers": [], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "species_1500581", "species_1500581", "Q8IJK2", "PF3D7_1019900" ] }, "reaction_10703360": { "compartment": "compartment_70101", "id": "reaction_10703360", "reactome": "R-PFA-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697365" ], "products": [ "species_10697459" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "C6S3K2", "PF3D7_1470000", "C6S3K2", "PF3D7_1470000", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697367": { "compartment": "compartment_70101", "id": "reaction_10697367", "reactome": "R-PFA-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697361", "species_10697363" ], "products": [ "species_10697365" ], "modifiers": [], "additional_components": [ "PF3D7_1470000", "Q8IIA3", "PF3D7_1126100", "Q8IIA3", "PF3D7_1126100", "C6S3K2", "PF3D7_1470000" ] }, "reaction_10697463": { "compartment": "compartment_70101", "id": "reaction_10697463", "reactome": "R-PFA-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697378" ], "products": [ "species_10697355", "species_10697363" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697461": { "compartment": "compartment_70101", "id": "reaction_10697461", "reactome": "R-PFA-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697374", "species_10697359" ], "products": [ "species_10697376" ], "modifiers": [], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100", "PF3D7_0905700.2", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697381": { "compartment": "compartment_70101", "id": "reaction_10697381", "reactome": "R-PFA-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697376" ], "products": [ "species_10697378" ], "modifiers": [ [ "species_10697376", "catalyst" ] ], "additional_components": [ "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100", "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697407": { "compartment": "compartment_70101", "id": "reaction_10697407", "reactome": "R-PFA-5681987", "name": "LC3 is cleaved by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697391" ], "products": [ "species_10697347" ], "modifiers": [ [ "species_10697404", "catalyst" ] ], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "Q8IJK2", "PF3D7_1019900", "Q8ILS3", "PF3D7_1417300" ] }, "reaction_10703521": { "compartment": "compartment_70101", "id": "reaction_10703521", "reactome": "R-PFA-9641096", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703517", "species_10703502" ], "products": [ "species_10703519" ], "modifiers": [], "additional_components": [ "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600" ] }, "reaction_10703504": { "compartment": "compartment_70101", "id": "reaction_10703504", "reactome": "R-PFA-9641089", "name": "Parkin binds Ub:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703500", "species_10693227" ], "products": [ "species_10703502" ], "modifiers": [], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "PF3D7_0303800", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700" ] }, "reaction_10703543": { "compartment": "compartment_70101", "id": "reaction_10703543", "reactome": "R-PFA-9641109", "name": "PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703541" ], "products": [ "species_10703539", "species_10703523" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700" ] }, "reaction_10703563": { "compartment": "compartment_70101", "id": "reaction_10703563", "reactome": "R-PFA-9641111", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703519" ], "products": [ "species_10703561" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500" ] }, "reaction_10703565": { "compartment": "compartment_70101", "id": "reaction_10703565", "reactome": "R-PFA-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703561" ], "products": [ "species_10703541" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600" ] }, "reaction_10703283": { "compartment": "compartment_70101", "id": "reaction_10703283", "reactome": "R-PFA-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10687116", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10687426": { "compartment": "compartment_70101", "id": "reaction_10687426", "reactome": "R-PFA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10687423", "catalyst" ] ], "additional_components": [ "Q8I5L3", "PF3D7_1219900", "species_71067" ] }, "reaction_10699327": { "compartment": "compartment_70101", "id": "reaction_10699327", "reactome": "R-PFA-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10687116", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10690381": { "compartment": "compartment_70101", "id": "reaction_10690381", "reactome": "R-PFA-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10687423", "catalyst" ] ], "additional_components": [ "Q8I5L3", "PF3D7_1219900", "species_71067" ] }, "reaction_10697188": { "compartment": "compartment_70101", "id": "reaction_10697188", "reactome": "R-PFA-5661256", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5661264", "species_29364" ], "products": [ "species_29366", "species_5661268" ], "modifiers": [ [ "species_10697185", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10692240": { "compartment": "compartment_7660", "id": "reaction_10692240", "reactome": "R-PFA-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692236", "species_450613" ], "products": [ "species_10692238" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10692472": { "compartment": "compartment_7660", "id": "reaction_10692472", "reactome": "R-PFA-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450605", "species_10692247" ], "products": [ "species_10692470" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10692476": { "compartment": "compartment_7660", "id": "reaction_10692476", "reactome": "R-PFA-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692244", "species_517622" ], "products": [ "species_10692474" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10697334": { "compartment": "compartment_70101", "id": "reaction_10697334", "reactome": "R-PFA-5676966", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5687536", "species_71284" ], "products": [ "species_5687529", "species_71285" ], "modifiers": [ [ "species_10697331", "catalyst" ] ], "additional_components": [ "PF3D7_1432700" ] }, "reaction_10694769": { "compartment": "compartment_70101", "id": "reaction_10694769", "reactome": "R-PFA-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_111294", "species_111584" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10694772": { "compartment": "compartment_70101", "id": "reaction_10694772", "reactome": "R-PFA-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_111294", "species_109330" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10694766": { "compartment": "compartment_70101", "id": "reaction_10694766", "reactome": "R-PFA-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_111294", "species_29602" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10702430": { "compartment": "compartment_7660", "id": "reaction_10702430", "reactome": "R-PFA-8866601", "name": "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_8866574" ], "products": [ "species_8866608", "species_8866567" ], "modifiers": [ [ "species_10702427", "catalyst" ], [ "species_29892", "catalyst" ] ], "additional_components": [ "Q8I533", "PF3D7_1239000", "species_216785" ] }, "reaction_10699367": { "compartment": "compartment_5460", "id": "reaction_10699367", "reactome": "R-PFA-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6788802" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10699364", "catalyst" ] ], "additional_components": [ "species_109395", "species_109386", "species_76577", "CHEBI:15918", "species_113582", "CHEBI:16174", "CHEBI:28846", "species_110094", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600" ] }, "reaction_10688358": { "compartment": "compartment_70101", "id": "reaction_10688358", "reactome": "R-PFA-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500071" ], "products": [ "species_29370", "species_500077" ], "modifiers": [ [ "species_10688355", "catalyst" ] ], "additional_components": [ "species_113578", "CHEBI:16192", "species_29420", "CHEBI:28862", "PF3D7_0928900" ] }, "reaction_10699375": { "compartment": "compartment_7660", "id": "reaction_10699375", "reactome": "R-PFA-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6788813" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10699372", "catalyst" ] ], "additional_components": [ "CHEBI:15918", "species_109395", "species_76577", "species_109386", "species_110094", "CHEBI:16174", "CHEBI:28846", "species_113582", "PF3D7_0110900" ] }, "reaction_10688302": { "compartment": "compartment_70101", "id": "reaction_10688302", "reactome": "R-PFA-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355", "species_109382" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10688299", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I1R6", "PF3D7_0417200" ] }, "reaction_10692407": { "compartment": "compartment_5460", "id": "reaction_10692407", "reactome": "R-PFA-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113581", "species_482807" ], "products": [ "species_113593", "species_482803" ], "modifiers": [ [ "species_10692402", "catalyst" ] ], "additional_components": [ "species_110577", "species_29438", "species_500739", "species_29892", "species_29494", "species_110644", "species_30185", "species_30187", "CHEBI:18075", "species_29420", "CHEBI:28850", "CHEBI:28862", "species_205687", "CHEBI:16174", "CHEBI:28846", "species_110094", "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10689211": { "compartment": "compartment_70101", "id": "reaction_10689211", "reactome": "R-PFA-111746", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_10689189" ], "products": [ "species_10689186", "species_111745" ], "modifiers": [ [ "species_10689189", "catalyst" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "PF3D7_0306300" ] }, "reaction_10688312": { "compartment": "compartment_70101", "id": "reaction_10688312", "reactome": "R-PFA-73635", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_499997", "species_113592" ], "products": [ "species_29370", "species_499999" ], "modifiers": [ [ "species_10688309", "catalyst" ] ], "additional_components": [ "species_500742", "species_109366", "CHEBI:28850", "CHEBI:18075", "Q8I4S1", "PF3D7_1251300" ] }, "reaction_10689208": { "compartment": "compartment_70101", "id": "reaction_10689208", "reactome": "R-PFA-111742", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10689186" ], "products": [ "species_29356", "species_8866399", "species_10689189" ], "modifiers": [ [ "species_10689205", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688895": { "compartment": "compartment_70101", "id": "reaction_10688895", "reactome": "R-PFA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788778", "species_113592" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10688890", "catalyst" ] ], "additional_components": [ "species_76577", "species_109395", "CHEBI:15918", "species_109386", "species_113582", "CHEBI:28846", "CHEBI:16174", "species_110094", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600", "Q8I231", "PF3D7_0816900", "Q8IB06", "PF3D7_0816900" ] }, "reaction_10689214": { "compartment": "compartment_70101", "id": "reaction_10689214", "reactome": "R-PFA-111751", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10688320" ], "products": [ "species_10688318", "species_29356", "species_8866399" ], "modifiers": [ [ "species_10689205", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688893": { "compartment": "compartment_70101", "id": "reaction_10688893", "reactome": "R-PFA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_6788778", "species_113592" ], "modifiers": [ [ "species_10688890", "catalyst" ] ], "additional_components": [ "species_113582", "CHEBI:28846", "CHEBI:16174", "species_110094", "species_76577", "species_109395", "CHEBI:15918", "species_109386", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600", "Q8I231", "PF3D7_0816900", "Q8IB06", "PF3D7_0816900" ] }, "reaction_10701181": { "compartment": "compartment_70101", "id": "reaction_10701181", "reactome": "R-PFA-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6806885" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10701178", "catalyst" ] ], "additional_components": [ "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10692419": { "compartment": "compartment_70101", "id": "reaction_10692419", "reactome": "R-PFA-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10692416", "catalyst" ] ], "additional_components": [ "Q8ILZ3", "PF3D7_1410200" ] }, "reaction_10688897": { "compartment": "compartment_70101", "id": "reaction_10688897", "reactome": "R-PFA-110141", "name": "(d)ADP + ADP <=> (d)AMP + ATP (AK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_500087" ], "products": [ "species_500088", "species_113592" ], "modifiers": [ [ "species_10688385", "catalyst" ] ], "additional_components": [ "species_113582", "CHEBI:16174", "species_76577", "species_109386", "PF3D7_0816900" ] }, "reaction_10688906": { "compartment": "compartment_70101", "id": "reaction_10688906", "reactome": "R-PFA-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10688903", "catalyst" ] ], "additional_components": [ "Q8I1T1", "PF3D7_0415600", "Q8IJV6", "PF3D7_1008900" ] }, "reaction_10692362": { "compartment": "compartment_70101", "id": "reaction_10692362", "reactome": "R-PFA-482621", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_482625" ], "products": [ "species_113592", "species_482627" ], "modifiers": [ [ "species_10692357", "catalyst" ] ], "additional_components": [ "species_29892", "species_110644", "species_30185", "species_29494", "species_30187", "species_110577", "species_500739", "species_29438", "species_205687", "CHEBI:28846", "CHEBI:16174", "species_29420", "CHEBI:28850", "CHEBI:28862", "CHEBI:18075", "species_110094", "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10689230": { "compartment": "compartment_70101", "id": "reaction_10689230", "reactome": "R-PFA-111804", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10688320" ], "products": [ "species_10688318", "species_29356", "species_8866399" ], "modifiers": [ [ "species_10689227", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "Q8IJN8", "PF3D7_1405600", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688340": { "compartment": "compartment_70101", "id": "reaction_10688340", "reactome": "R-PFA-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10688337", "catalyst" ] ], "additional_components": [ "Q8ILZ3", "PF3D7_1410200" ] }, "reaction_10702420": { "compartment": "compartment_70101", "id": "reaction_10702420", "reactome": "R-PFA-8866405", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10689186" ], "products": [ "species_29356", "species_8866399", "species_10689189" ], "modifiers": [ [ "species_10689227", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "Q8IJN8", "PF3D7_1405600", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688350": { "compartment": "compartment_7660", "id": "reaction_10688350", "reactome": "R-PFA-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742" ], "modifiers": [ [ "species_10688347", "catalyst" ] ], "additional_components": [ "Q8II92", "PF3D7_1127100" ] }, "reaction_10692257": { "compartment": "compartment_5462", "id": "reaction_10692257", "reactome": "R-PFA-450971", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113526", "species_113600" ], "products": [ "species_113563", "species_113529", "species_29362" ], "modifiers": [ [ "species_10692254", "catalyst" ] ], "additional_components": [ "Q8IKU3", "PF3D7_1453500" ] }, "reaction_10687520": { "compartment": "compartment_5460", "id": "reaction_10687520", "reactome": "R-PFA-71775", "name": "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_113548", "species_113525" ], "products": [ "species_29374", "species_113573", "species_113536" ], "modifiers": [ [ "species_10687517", "catalyst" ] ], "additional_components": [ "Q8IIR8", "PF3D7_1108500", "Q8ILE9", "PF3D7_1431600" ] }, "reaction_10687364": { "compartment": "compartment_5460", "id": "reaction_10687364", "reactome": "R-PFA-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113587", "species_113521" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10687361", "catalyst" ] ], "additional_components": [ "Q8I6U7", "PF3D7_1022500" ] }, "reaction_10687428": { "compartment": "compartment_5460", "id": "reaction_10687428", "reactome": "R-PFA-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_70958", "species_29362", "species_29376" ], "modifiers": [ [ "species_10687393", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10692267": { "compartment": "compartment_5460", "id": "reaction_10692267", "reactome": "R-PFA-450984", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_29938" ], "products": [ "species_113594", "species_113529", "species_113600", "species_29376" ], "modifiers": [ [ "species_10692264", "catalyst" ] ], "additional_components": [ "Q8I6T2", "PF3D7_1345700", "species_1981162" ] }, "reaction_10691918": { "compartment": "compartment_876", "id": "reaction_10691918", "reactome": "R-PFA-444008", "name": "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_114523", "species_74113" ], "products": [ "species_209914", "species_83910", "species_352022" ], "modifiers": [ [ "species_10691915", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10687636": { "compartment": "compartment_7660", "id": "reaction_10687636", "reactome": "R-PFA-72095", "name": "Internal Methylation of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687608" ], "products": [ "species_10687616" ], "modifiers": [ [ "species_10687633", "catalyst" ] ], "additional_components": [ "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I6Z2", "PF3D7_0729500", "Q8I567", "PF3D7_1235500", "Q8I5B2", "PF3D7_1230800" ] }, "reaction_10694523": { "compartment": "compartment_70101", "id": "reaction_10694523", "reactome": "R-PFA-2161500", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161525" ], "products": [ "species_2161185" ], "modifiers": [ [ "species_10694520", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10690615": { "compartment": "compartment_20699", "id": "reaction_10690615", "reactome": "R-PFA-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690542", "species_200993" ], "products": [ "species_10690595" ], "modifiers": [ [ "species_10690612", "catalyst" ] ], "additional_components": [ "PF3D7_0923200", "PF3D7_0923200", "Q8IIK6", "PF3D7_1322500", "A0A143ZYC1", "PF3D7_1322500", "Q8IE90", "PF3D7_1322500" ] }, "reaction_10690550": { "compartment": "compartment_20699", "id": "reaction_10690550", "reactome": "R-PFA-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690544" ], "products": [ "species_10690548" ], "modifiers": [], "additional_components": [ "species_917877", "species_216785", "species_73524", "species_29386", "C0H553", "PF3D7_0923200", "species_29870", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870" ] }, "reaction_10690629": { "compartment": "compartment_20699", "id": "reaction_10690629", "reactome": "R-PFA-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690595" ], "products": [ "species_10690485" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386" ] }, "reaction_10690619": { "compartment": "compartment_70101", "id": "reaction_10690619", "reactome": "R-PFA-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_184174", "species_10690617" ], "products": [ "species_10690542" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "PF3D7_0923200" ] }, "reaction_10693934": { "compartment": "compartment_70101", "id": "reaction_10693934", "reactome": "R-PFA-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364" ], "products": [ "species_1222424", "species_29366" ], "modifiers": [ [ "species_10693929", "catalyst" ] ], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "species_1497857", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10691747": { "compartment": "compartment_70101", "id": "reaction_10691747", "reactome": "R-PFA-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691712", "species_429974" ], "products": [ "species_10691714" ], "modifiers": [], "additional_components": [ "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200" ] }, "reaction_10691745": { "compartment": "compartment_70101", "id": "reaction_10691745", "reactome": "R-PFA-429860", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10691714" ], "products": [ "species_10691716", "species_430004" ], "modifiers": [ [ "species_10691742", "catalyst" ] ], "additional_components": [ "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "Q8IEM5", "PF3D7_1308900", "C6KSR4", "PF3D7_0606600", "Q8IJ85", "PF3D7_1032100", "O97285", "PF3D7_0320800" ] }, "reaction_10689987": { "compartment": "compartment_876", "id": "reaction_10689987", "reactome": "R-PFA-189222", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189049" ], "products": [ "species_29532" ], "modifiers": [ [ "species_10689984", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10689998": { "compartment": "compartment_876", "id": "reaction_10689998", "reactome": "R-PFA-189242", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189246" ], "products": [ "species_189219" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "species_70115", "CHEBI:17118", "species_29532", "CHEBI:17118", "species_70115", "species_29532", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10697522": { "compartment": "compartment_12045", "id": "reaction_10697522", "reactome": "R-PFA-5685649", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697518" ], "products": [ "species_10697520" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10703245": { "compartment": "compartment_12045", "id": "reaction_10703245", "reactome": "R-PFA-8961021", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703241" ], "products": [ "species_10703243" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10703484": { "compartment": "compartment_12045", "id": "reaction_10703484", "reactome": "R-PFA-9624778", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703243" ], "products": [ "species_10703482" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10691053": { "compartment": "compartment_984", "id": "reaction_10691053", "reactome": "R-PFA-374919", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] } }, "motif_reaction_dictionary": { "reaction_10697020": { "compartment": "compartment_70101", "id": "reaction_10697020", "reactome": "R-PFA-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10690215", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10686578": { "compartment": "compartment_7660", "id": "reaction_10686578", "reactome": "R-PFA-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686546" ], "products": [ "species_10686556", "species_113582", "species_10686554" ], "modifiers": [ [ "species_10686575", "catalyst" ] ], "additional_components": [ "Q8I469", "PF3D7_0503200", "A0A5K1K8V1", "PF3D7_1334100", "O96237", "PF3D7_0215800", "Q8IC17", "PF3D7_0705300", "Q8I5T7", "PF3D7_1211300", "Q8I615", "PF3D7_1203000", "Q8I3J5", "PF3D7_0527000", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "Q8I5T4", "PF3D7_1211700", "Q8ILR7", "PF3D7_1417800", "Q8I3J5", "PF3D7_0527000", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "Q8I5T4", "PF3D7_1211700", "Q8ILR7", "PF3D7_1417800", "Q8I469", "PF3D7_0503200", "A0A5K1K8V1", "PF3D7_1334100", "O96237", "PF3D7_0215800", "Q8IC17", "PF3D7_0705300", "Q8I5T7", "PF3D7_1211300", "PF3D7_1203000", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10686674": { "compartment": "compartment_7660", "id": "reaction_10686674", "reactome": "R-PFA-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686649", "species_10686554" ], "products": [ "species_10686652" ], "modifiers": [ [ "species_10686671", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "PF3D7_1203000", "PF3D7_1203000", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10686678": { "compartment": "compartment_7660", "id": "reaction_10686678", "reactome": "R-PFA-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686652" ], "products": [ "species_10686676" ], "modifiers": [], "additional_components": [ "PF3D7_1203000", "PF3D7_1203000" ] }, "reaction_10686937": { "compartment": "compartment_70101", "id": "reaction_10686937", "reactome": "R-PFA-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686676" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "PF3D7_1203000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10686976": { "compartment": "compartment_7660", "id": "reaction_10686976", "reactome": "R-PFA-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686544" ], "products": [ "species_10686974", "species_10686542", "species_10686527", "species_10686517" ], "modifiers": [], "additional_components": [ "Q8I3J5", "PF3D7_0527000", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "Q8I5T4", "PF3D7_1211700", "Q8ILR7", "PF3D7_1417800", "Q8IDF0", "PF3D7_1355100", "Q8IEE5", "PF3D7_1317100", "Q8IC16", "PF3D7_0705400", "PF3D7_1417800", "PF3D7_1211700", "PF3D7_0527000" ] }, "reaction_10686962": { "compartment": "compartment_7660", "id": "reaction_10686962", "reactome": "R-PFA-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686407" ], "products": [ "species_113582", "species_10686949" ], "modifiers": [ [ "species_10686959", "catalyst" ] ], "additional_components": [ "PF3D7_0503200", "PF3D7_0503200", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IC23", "PF3D7_0704700" ] }, "reaction_10686966": { "compartment": "compartment_7660", "id": "reaction_10686966", "reactome": "R-PFA-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686949" ], "products": [ "species_10686964" ], "modifiers": [], "additional_components": [ "PF3D7_0503200", "PF3D7_0503200" ] }, "reaction_10686972": { "compartment": "compartment_70101", "id": "reaction_10686972", "reactome": "R-PFA-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686970" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I469", "PF3D7_0503200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10691078": { "compartment": "compartment_70101", "id": "reaction_10691078", "reactome": "R-PFA-379464", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9677997", "species_71284" ], "products": [ "species_9677992", "species_174369" ], "modifiers": [ [ "species_10691067", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10703494": { "compartment": "compartment_1598585", "id": "reaction_10703494", "reactome": "R-PFA-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10699285" ], "products": [ "species_10703486", "species_29420" ], "modifiers": [ [ "species_10703491", "catalyst" ] ], "additional_components": [ "Q7KQK6", "PF3D7_1117700", "species_29420", "Q7KQK6", "PF3D7_1117700", "species_29438", "PF3D7_0711500" ] }, "reaction_10703498": { "compartment": "compartment_70101", "id": "reaction_10703498", "reactome": "R-PFA-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10703486" ], "products": [ "species_10703496" ], "modifiers": [], "additional_components": [ "Q7KQK6", "PF3D7_1117700", "species_29438", "Q7KQK6", "PF3D7_1117700", "species_29438" ] }, "reaction_10691051": { "compartment": "compartment_876", "id": "reaction_10691051", "reactome": "R-PFA-374896", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10691300": { "compartment": "compartment_70101", "id": "reaction_10691300", "reactome": "R-PFA-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10691297", "catalyst" ] ], "additional_components": [ "Q8IKD3", "PF3D7_1470500", "Q8I6Z7", "PF3D7_1321500.1", "B3FEM7", "PF3D7_1321600" ] }, "reaction_10691242": { "compartment": "compartment_70101", "id": "reaction_10691242", "reactome": "R-PFA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10691239", "catalyst" ] ], "additional_components": [ "C0H553", "PF3D7_0923200" ] }, "reaction_10699877": { "compartment": "compartment_1222693", "id": "reaction_10699877", "reactome": "R-PFA-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_1629751", "species_29370" ], "modifiers": [ [ "species_10699874", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10703237": { "compartment": "compartment_70101", "id": "reaction_10703237", "reactome": "R-PFA-8959510", "name": "SEPHS2 phosphorylates H2Se to form SELP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357660", "species_29356", "species_113592" ], "products": [ "species_29372", "species_70106", "species_8959518", "species_76577" ], "modifiers": [ [ "species_10703234", "catalyst" ] ], "additional_components": [ "PF3D7_0910400" ] }, "reaction_10694885": { "compartment": "compartment_70101", "id": "reaction_10694885", "reactome": "R-PFA-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694412", "species_10690526", "species_74016" ], "products": [ "species_10694857" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "Q8IKV9", "PF3D7_1451700", "species_74016", "P62203", "PF14_0323", "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700" ] }, "reaction_10695764": { "compartment": "compartment_70101", "id": "reaction_10695764", "reactome": "R-PFA-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695758" ], "products": [ "species_10695762" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700", "species_74016", "Q8IKV9", "PF3D7_1451700", "P62203", "PF14_0323", "Q8IAM8", "PF3D7_0802800", "CHEBI:29034", "species_216785" ] }, "reaction_10695726": { "compartment": "compartment_7660", "id": "reaction_10695726", "reactome": "R-PFA-4411373", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695720" ], "products": [ "species_10695724" ], "modifiers": [], "additional_components": [ "Q7KQK7", "PF3D7_1113900", "Q7KQK7", "PF3D7_1113900" ] }, "reaction_10693951": { "compartment": "compartment_70101", "id": "reaction_10693951", "reactome": "R-PFA-1504193", "name": "Ubiquitinated DVL is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693946" ], "products": [ "species_10686740", "species_10693938" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10693949": { "compartment": "compartment_70101", "id": "reaction_10693949", "reactome": "R-PFA-1504190", "name": "DVL is ubiquitinated by CUL3:KLHL12:RBX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10693942" ], "products": [ "species_10693946" ], "modifiers": [ [ "species_10693942", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10690643": { "compartment": "compartment_7660", "id": "reaction_10690643", "reactome": "R-PFA-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10690340" ], "products": [ "species_113550", "species_10690391" ], "modifiers": [ [ "species_10690640", "catalyst" ] ], "additional_components": [ "Q7KQK7", "PF3D7_1113900", "Q7KQK7", "PF3D7_1113900", "Q8IKS8", "PF3D7_1455100" ] }, "reaction_10690343": { "compartment": "compartment_7660", "id": "reaction_10690343", "reactome": "R-PFA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10690313" ], "products": [ "species_113582", "species_10690338" ], "modifiers": [ [ "species_10690340", "catalyst" ] ], "additional_components": [ "Q8I4W3", "PF3D7_1246900", "Q8I4W3", "PF3D7_1246900", "Q7KQK7", "PF3D7_1113900" ] }, "reaction_10697570": { "compartment": "compartment_7660", "id": "reaction_10697570", "reactome": "R-PFA-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697549" ], "products": [ "species_10697568" ], "modifiers": [], "additional_components": [ "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900" ] }, "reaction_10698160": { "compartment": "compartment_70101", "id": "reaction_10698160", "reactome": "R-PFA-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698156", "species_10695314" ], "products": [ "species_10698158" ], "modifiers": [], "additional_components": [ "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "PF3D7_0201800", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900" ] }, "reaction_10698170": { "compartment": "compartment_70101", "id": "reaction_10698170", "reactome": "R-PFA-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698158", "species_113592" ], "products": [ "species_29370", "species_10698167" ], "modifiers": [ [ "species_10698158", "catalyst" ] ], "additional_components": [ "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "O96123", "PF3D7_0201800", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900" ] }, "reaction_10697560": { "compartment": "compartment_7660", "id": "reaction_10697560", "reactome": "R-PFA-5687088", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10697538" ], "products": [ "species_113582", "species_10697549" ], "modifiers": [ [ "species_10697557", "catalyst" ] ], "additional_components": [ "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "A0A5K1K8V9", "PF3D7_1338900", "Q8IIV3", "PF3D7_1104900", "Q8I534", "PF3D7_1338900", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800", "C0H4P1", "PF3D7_0934800" ] }, "reaction_10688929": { "compartment": "compartment_7660", "id": "reaction_10688929", "reactome": "R-PFA-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688922" ], "products": [ "species_10688926", "species_29554" ], "modifiers": [ [ "species_10688922", "catalyst" ] ], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000" ] }, "reaction_10688945": { "compartment": "compartment_7660", "id": "reaction_10688945", "reactome": "R-PFA-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688940" ], "products": [ "species_110223", "species_10688942" ], "modifiers": [ [ "species_10688940", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688966": { "compartment": "compartment_7660", "id": "reaction_10688966", "reactome": "R-PFA-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688963" ], "products": [ "species_5637659", "species_10688942" ], "modifiers": [ [ "species_10688963", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688936": { "compartment": "compartment_7660", "id": "reaction_10688936", "reactome": "R-PFA-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688933" ], "products": [ "species_10688926", "species_110216" ], "modifiers": [ [ "species_10688933", "catalyst" ] ], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000", "Q8ILU6", "PF3D7_1415000" ] }, "reaction_10688952": { "compartment": "compartment_7660", "id": "reaction_10688952", "reactome": "R-PFA-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688949" ], "products": [ "species_10688942", "species_110225" ], "modifiers": [ [ "species_10688949", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688959": { "compartment": "compartment_7660", "id": "reaction_10688959", "reactome": "R-PFA-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688956" ], "products": [ "species_10688942", "species_30140" ], "modifiers": [ [ "species_10688956", "catalyst" ] ], "additional_components": [ "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800", "C6KSY9", "PF3D7_0614800" ] }, "reaction_10688990": { "compartment": "compartment_7660", "id": "reaction_10688990", "reactome": "R-PFA-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688987" ], "products": [ "species_10688982", "species_5636006" ], "modifiers": [ [ "species_10688987", "catalyst" ] ], "additional_components": [ "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100" ] }, "reaction_10703130": { "compartment": "compartment_17906", "id": "reaction_10703130", "reactome": "R-PFA-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703122" ], "products": [ "species_10703128" ], "modifiers": [], "additional_components": [ "Q8IHR5", "PF3D7_1145200", "C0H563", "PF3D7_1145200", "Q8IHR5", "PF3D7_1145200", "C0H563", "PF3D7_1145200" ] }, "reaction_10699391": { "compartment": "compartment_984", "id": "reaction_10699391", "reactome": "R-PFA-6789310", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174675", "species_6789319" ], "modifiers": [ [ "species_10699388", "catalyst" ] ], "additional_components": [ "Q8II98", "PF3D7_1126600" ] }, "reaction_10691303": { "compartment": "compartment_70101", "id": "reaction_10691303", "reactome": "R-PFA-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10691295", "catalyst" ] ], "additional_components": [ "Q8IKD3", "PF3D7_1470500", "Q8I6Z7", "PF3D7_1321500.1", "B3FEM7", "PF3D7_1321600" ] }, "reaction_10695969": { "compartment": "compartment_7660", "id": "reaction_10695969", "reactome": "R-PFA-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10687012" ], "products": [ "species_10695967", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF13_0328", "Q8I444", "PF3D7_0505800", "P61074", "PF13_0328", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10696010": { "compartment": "compartment_7660", "id": "reaction_10696010", "reactome": "R-PFA-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10696001" ], "products": [ "species_10696008", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1433500", "Q8ILC8", "PF3D7_1433500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695999": { "compartment": "compartment_7660", "id": "reaction_10695999", "reactome": "R-PFA-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695989" ], "products": [ "species_10695997", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1433500", "Q8I444", "PF3D7_0505800", "Q8ILC8", "PF3D7_1433500", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10696015": { "compartment": "compartment_7660", "id": "reaction_10696015", "reactome": "R-PFA-4641350", "name": "PIAS4 SUMOylates TOP2A with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695835", "species_10695989" ], "products": [ "species_10696013", "species_10694930" ], "modifiers": [ [ "species_10695666", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1433500", "PF3D7_1433500", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10696030": { "compartment": "compartment_7660", "id": "reaction_10696030", "reactome": "R-PFA-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10696020" ], "products": [ "species_10696028", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0510500", "Q8I3Z9", "PF3D7_0510500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10690228": { "compartment": "compartment_70101", "id": "reaction_10690228", "reactome": "R-PFA-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_113592", "species_196786" ], "products": [ "species_111294", "species_196834", "species_76577" ], "modifiers": [ [ "species_10690225", "catalyst" ] ], "additional_components": [ "Q9U0G7", "PF3D7_0412300" ] }, "reaction_10690248": { "compartment": "compartment_70101", "id": "reaction_10690248", "reactome": "R-PFA-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10690245", "catalyst" ] ], "additional_components": [ "Q8IAZ8", "PF3D7_0816100", "species_73524" ] }, "reaction_10694915": { "compartment": "compartment_7660", "id": "reaction_10694915", "reactome": "R-PFA-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10694902", "species_10694897" ], "products": [ "species_164121", "species_113541", "species_10694912" ], "modifiers": [ [ "species_10694897", "catalyst" ] ], "additional_components": [ "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8I444", "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000" ] }, "reaction_10694941": { "compartment": "compartment_7660", "id": "reaction_10694941", "reactome": "R-PFA-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694912", "species_10694930" ], "products": [ "species_10694938", "species_10694897" ], "modifiers": [ [ "species_10694897", "catalyst" ] ], "additional_components": [ "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000", "Q8IHS2", "PF3D7_1144500", "Q8I553", "PF3D7_1237000" ] }, "reaction_10689122": { "compartment": "compartment_7660", "id": "reaction_10689122", "reactome": "R-PFA-110354", "name": "Displacement of OGG1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689114", "species_10688982" ], "products": [ "species_10689116", "species_10688971" ], "modifiers": [], "additional_components": [ "PF3D7_0305600", "Q8I2Y2", "PF3D7_0917100", "O97240", "PF3D7_0305600", "PF3D7_0917100" ] }, "reaction_10689120": { "compartment": "compartment_7660", "id": "reaction_10689120", "reactome": "R-PFA-110352", "name": "Displacement of NTHL1 glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688942", "species_10689114" ], "products": [ "species_10689116", "species_10688913" ], "modifiers": [], "additional_components": [ "C6KSY9", "PF3D7_0614800", "PF3D7_0305600", "O97240", "PF3D7_0305600", "PF3D7_0614800" ] }, "reaction_10689126": { "compartment": "compartment_7660", "id": "reaction_10689126", "reactome": "R-PFA-110356", "name": "Displacement of MPG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689114", "species_10689014" ], "products": [ "species_10689116", "species_10688976" ], "modifiers": [], "additional_components": [ "PF3D7_0305600", "Q8IKG6", "PF3D7_1467100", "O97240", "PF3D7_0305600", "PF3D7_1467100" ] }, "reaction_10689124": { "compartment": "compartment_7660", "id": "reaction_10689124", "reactome": "R-PFA-110355", "name": "Displacement of MUTYH glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689005", "species_10689114" ], "products": [ "species_10689116", "species_10689001" ], "modifiers": [], "additional_components": [ "A0A143ZYC4", "PF3D7_1129500", "PF3D7_0305600", "O97240", "PF3D7_0305600", "A0A143ZYC4", "PF3D7_1129500" ] }, "reaction_10689118": { "compartment": "compartment_7660", "id": "reaction_10689118", "reactome": "R-PFA-110349", "name": "Displacement of UNG glycosylase by APEX1 at the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688926", "species_10689114" ], "products": [ "species_10689116", "species_10688920" ], "modifiers": [], "additional_components": [ "Q8ILU6", "PF3D7_1415000", "PF3D7_0305600", "O97240", "PF3D7_0305600", "PF3D7_1415000" ] }, "reaction_10694851": { "compartment": "compartment_876", "id": "reaction_10694851", "reactome": "R-PFA-2534365", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10694848", "catalyst" ] ], "additional_components": [ "Q8ILA3", "PF3D7_1436100" ] }, "reaction_10695003": { "compartment": "compartment_7660", "id": "reaction_10695003", "reactome": "R-PFA-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694993" ], "products": [ "species_29478", "species_10694995" ], "modifiers": [ [ "species_10695000", "catalyst" ] ], "additional_components": [ "PF3D7_1211600" ] }, "reaction_10697178": { "compartment": "compartment_7660", "id": "reaction_10697178", "reactome": "R-PFA-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696046" ], "products": [ "species_29478", "species_10694993" ], "modifiers": [ [ "species_10695000", "catalyst" ] ], "additional_components": [ "PF3D7_1211600" ] }, "reaction_10696062": { "compartment": "compartment_7660", "id": "reaction_10696062", "reactome": "R-PFA-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696046", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_10694993", "species_159939" ], "modifiers": [ [ "species_10696059", "catalyst" ] ], "additional_components": [ "Q8IAT4", "PF3D7_0809900" ] }, "reaction_10697164": { "compartment": "compartment_7660", "id": "reaction_10697164", "reactome": "R-PFA-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696441", "species_113671", "species_113685" ], "products": [ "species_10696046", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10696059", "catalyst" ] ], "additional_components": [ "Q8IAT4", "PF3D7_0809900" ] }, "reaction_10695575": { "compartment": "compartment_7660", "id": "reaction_10695575", "reactome": "R-PFA-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10695561" ], "products": [ "species_10695567", "species_5566518" ], "modifiers": [ [ "species_10695572", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "PF3D7_1008000" ] }, "reaction_10696930": { "compartment": "compartment_7660", "id": "reaction_10696930", "reactome": "R-PFA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694993" ], "products": [ "species_77502", "species_10696046" ], "modifiers": [ [ "species_10696443", "catalyst" ] ], "additional_components": [ "PF3D7_1355300" ] }, "reaction_10696961": { "compartment": "compartment_7660", "id": "reaction_10696961", "reactome": "R-PFA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696040" ], "products": [ "species_77502", "species_10696949" ], "modifiers": [ [ "species_10696101", "catalyst" ] ], "additional_components": [ "Q8IIL1", "PF3D7_1115200", "Q8I352", "PF3D7_1115200", "Q8IDE8", "PF3D7_1355300" ] }, "reaction_10696688": { "compartment": "compartment_7660", "id": "reaction_10696688", "reactome": "R-PFA-5423038", "name": "SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10689874" ], "products": [ "species_77502", "species_10694646" ], "modifiers": [ [ "species_10694706", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "PF3D7_0403900" ] }, "reaction_10696104": { "compartment": "compartment_7660", "id": "reaction_10696104", "reactome": "R-PFA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694995" ], "products": [ "species_77502", "species_10696040" ], "modifiers": [ [ "species_10696101", "catalyst" ] ], "additional_components": [ "Q8IIL1", "PF3D7_1115200", "Q8I352", "PF3D7_1115200", "Q8IDE8", "PF3D7_1355300" ] }, "reaction_10696446": { "compartment": "compartment_7660", "id": "reaction_10696446", "reactome": "R-PFA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696046" ], "products": [ "species_77502", "species_10696441" ], "modifiers": [ [ "species_10696443", "catalyst" ], [ "species_10696247", "inhibitor" ] ], "additional_components": [ "PF3D7_1355300" ] }, "reaction_10695392": { "compartment": "compartment_7660", "id": "reaction_10695392", "reactome": "R-PFA-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10689874" ], "products": [ "species_2485002", "species_10695365" ], "modifiers": [ [ "species_10695389", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300", "C0H4A7", "PF3D7_0416400" ] }, "reaction_10696439": { "compartment": "compartment_7660", "id": "reaction_10696439", "reactome": "R-PFA-5229203", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696420" ], "products": [ "species_77502", "species_10696437" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696182": { "compartment": "compartment_7660", "id": "reaction_10696182", "reactome": "R-PFA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10689874" ], "products": [ "species_77502", "species_10696172" ], "modifiers": [ [ "species_10696179", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IHP7", "PF3D7_1147300", "Q8ILK1", "PF3D7_1426200" ] }, "reaction_10696293": { "compartment": "compartment_7660", "id": "reaction_10696293", "reactome": "R-PFA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696273" ], "products": [ "species_77502", "species_10696290" ], "modifiers": [ [ "species_10695008", "catalyst" ] ], "additional_components": [ "PF3D7_1426200" ] }, "reaction_10696219": { "compartment": "compartment_7660", "id": "reaction_10696219", "reactome": "R-PFA-5205820", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696199" ], "products": [ "species_77502", "species_10696216" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696249": { "compartment": "compartment_7660", "id": "reaction_10696249", "reactome": "R-PFA-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10696235" ], "products": [ "species_77502", "species_10696247" ], "modifiers": [ [ "species_10696177", "catalyst" ] ], "additional_components": [ "PF3D7_1147300" ] }, "reaction_10696335": { "compartment": "compartment_7660", "id": "reaction_10696335", "reactome": "R-PFA-5225649", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695387", "species_10694995" ], "products": [ "species_10696333" ], "modifiers": [ [ "species_10696321", "inhibitor" ] ], "additional_components": [ "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300", "Q8IE52", "PF3D7_1433300", "Q8ILD0", "PF3D7_1433300", "Q8I238", "PF3D7_1433300" ] }, "reaction_10697183": { "compartment": "compartment_7660", "id": "reaction_10697183", "reactome": "R-PFA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696172", "species_77087" ], "products": [ "species_77502", "species_10697181" ], "modifiers": [ [ "species_10696179", "catalyst" ] ], "additional_components": [ "PF3D7_1105000", "PF3D7_1105000", "Q8IHP7", "PF3D7_1147300", "Q8ILK1", "PF3D7_1426200" ] }, "reaction_10697206": { "compartment": "compartment_70101", "id": "reaction_10697206", "reactome": "R-PFA-5665871", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697198", "species_10686934" ], "products": [ "species_10697200" ], "modifiers": [], "additional_components": [ "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000" ] }, "reaction_10698293": { "compartment": "compartment_70101", "id": "reaction_10698293", "reactome": "R-PFA-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698284", "species_29356" ], "products": [ "species_10698288", "species_10698290" ], "modifiers": [ [ "species_10698284", "catalyst" ] ], "additional_components": [ "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "PF3D7_1313000", "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000" ] }, "reaction_10697204": { "compartment": "compartment_70101", "id": "reaction_10697204", "reactome": "R-PFA-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697193", "species_10697200" ], "products": [ "species_10697202" ], "modifiers": [], "additional_components": [ "PF3D7_1117100", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "Q8IIJ6", "PF3D7_1117100" ] }, "reaction_10698267": { "compartment": "compartment_70101", "id": "reaction_10698267", "reactome": "R-PFA-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698262" ], "products": [ "species_1131871", "species_10698264" ], "modifiers": [ [ "species_10698262", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IKM8", "PF3D7_1460400" ] }, "reaction_10687165": { "compartment": "compartment_70101", "id": "reaction_10687165", "reactome": "R-PFA-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10687122", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10687018": { "compartment": "compartment_7660", "id": "reaction_10687018", "reactome": "R-PFA-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10687005", "species_10687014" ], "products": [ "species_113582", "species_10687016" ], "modifiers": [], "additional_components": [ "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "P61074", "PF13_0328", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10687007": { "compartment": "compartment_7660", "id": "reaction_10687007", "reactome": "R-PFA-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686939", "species_10687003" ], "products": [ "species_10687005" ], "modifiers": [], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10687022": { "compartment": "compartment_7660", "id": "reaction_10687022", "reactome": "R-PFA-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687016" ], "products": [ "species_10687020", "species_10687003" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100" ] }, "reaction_10687059": { "compartment": "compartment_7660", "id": "reaction_10687059", "reactome": "R-PFA-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687055", "species_10687050" ], "products": [ "species_10687057" ], "modifiers": [], "additional_components": [ "PF3D7_1333900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "A0A5K1K9F2", "PF3D7_1333900" ] }, "reaction_10687071": { "compartment": "compartment_7660", "id": "reaction_10687071", "reactome": "R-PFA-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687061" ], "products": [ "species_10687063" ], "modifiers": [ [ "species_10687068", "catalyst" ] ], "additional_components": [ "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "PFD0420c" ] }, "reaction_10687079": { "compartment": "compartment_7660", "id": "reaction_10687079", "reactome": "R-PFA-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10687076", "catalyst" ] ], "additional_components": [ "PF3D7_1304100" ] }, "reaction_10687046": { "compartment": "compartment_7660", "id": "reaction_10687046", "reactome": "R-PFA-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687042" ], "products": [ "species_10687044" ], "modifiers": [], "additional_components": [ "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "O77321", "PF3D7_0308000", "Q7KQL4", "PF3D7_1017000", "P61074", "PF13_0328", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10689433": { "compartment": "compartment_70101", "id": "reaction_10689433", "reactome": "R-PFA-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689420", "species_10689429" ], "products": [ "species_10689431" ], "modifiers": [], "additional_components": [ "PF3D7_1004000", "Q8I5H4", "PF3D7_1224300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8I5H4", "PF3D7_1224300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJZ7", "PF3D7_1004000" ] }, "reaction_10689437": { "compartment": "compartment_70101", "id": "reaction_10689437", "reactome": "R-PFA-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688213" ], "products": [ "species_10688008", "species_10689435" ], "modifiers": [], "additional_components": [ "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "PF3D7_1004000", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200" ] }, "reaction_10698371": { "compartment": "compartment_70101", "id": "reaction_10698371", "reactome": "R-PFA-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29418", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1981162" ], "modifiers": [ [ "species_10698368", "catalyst" ] ], "additional_components": [ "PF3D7_0727800" ] }, "reaction_10691233": { "compartment": "compartment_114521", "id": "reaction_10691233", "reactome": "R-PFA-418365", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427899", "species_74016" ], "products": [ "species_70106", "species_139827" ], "modifiers": [ [ "species_10691230", "catalyst" ] ], "additional_components": [ "Q76NN8", "PF3D7_1211900", "A0A143ZZK9", "PF3D7_1211900" ] }, "reaction_10693014": { "compartment": "compartment_70101", "id": "reaction_10693014", "reactome": "R-PFA-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_947588", "species_113592" ], "products": [ "species_29372", "species_29370", "species_947594" ], "modifiers": [ [ "species_10692986", "catalyst" ] ], "additional_components": [ "species_1500646", "species_1500581", "species_1500581", "species_1500646", "Q8IKF1", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600" ] }, "reaction_10691562": { "compartment": "compartment_12045", "id": "reaction_10691562", "reactome": "R-PFA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_74016" ], "products": [ "species_70106", "species_111875" ], "modifiers": [ [ "species_10691559", "catalyst" ] ], "additional_components": [ "Q76NN8", "PF3D7_1211900", "A0A143ZZK9", "PF3D7_1211900" ] }, "reaction_10691208": { "compartment": "compartment_876", "id": "reaction_10691208", "reactome": "R-PFA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10691205", "catalyst" ] ], "additional_components": [ "A0A5K1K8L6", "PF3D7_1348800" ] }, "reaction_10698376": { "compartment": "compartment_70101", "id": "reaction_10698376", "reactome": "R-PFA-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5692450" ], "products": [ "species_29372", "species_29370", "species_5692484" ], "modifiers": [ [ "species_10698373", "catalyst" ] ], "additional_components": [ "PF3D7_0516100" ] }, "reaction_10696494": { "compartment": "compartment_70101", "id": "reaction_10696494", "reactome": "R-PFA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5252122", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5252016" ], "modifiers": [ [ "species_10696491", "catalyst" ] ], "additional_components": [ "Q8I3U7", "PF3D7_0516100" ] }, "reaction_10699216": { "compartment": "compartment_7660", "id": "reaction_10699216", "reactome": "R-PFA-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699209", "species_6781829" ], "products": [ "species_10699213", "species_113541" ], "modifiers": [ [ "species_10699209", "catalyst" ] ], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10699211": { "compartment": "compartment_7660", "id": "reaction_10699211", "reactome": "R-PFA-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687612", "species_10688666", "species_5688114" ], "products": [ "species_10699209" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10691010": { "compartment": "compartment_70101", "id": "reaction_10691010", "reactome": "R-PFA-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691000" ], "products": [ "species_10691008" ], "modifiers": [], "additional_components": [ "Q8IHR4", "PF3D7_1218500", "Q8IJ32", "PF3D7_1218500", "Q8I5M3", "PF3D7_1218500", "Q8I5M3", "PF3D7_1218500", "Q8IJ32", "PF3D7_1218500", "Q8IHR4", "PF3D7_1218500" ] }, "reaction_10690941": { "compartment": "compartment_7660", "id": "reaction_10690941", "reactome": "R-PFA-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690937", "species_29428" ], "products": [ "species_10690939" ], "modifiers": [], "additional_components": [ "Q8I616", "PF3D7_1202900", "Q8I616", "PF3D7_1202900" ] }, "reaction_10703624": { "compartment": "compartment_70101", "id": "reaction_10703624", "reactome": "R-PFA-9661417", "name": "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5679042" ], "products": [ "species_29372", "species_5679034", "species_29370" ], "modifiers": [ [ "species_10692753", "catalyst" ] ], "additional_components": [ "CHEBI:18392", "CHEBI:16427", "CHEBI:16427", "CHEBI:18392", "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690066": { "compartment": "compartment_5460", "id": "reaction_10690066", "reactome": "R-PFA-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_70958", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10690063", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "Q8I4X1", "PF3D7_1246100" ] }, "reaction_10690082": { "compartment": "compartment_70101", "id": "reaction_10690082", "reactome": "R-PFA-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10690035", "catalyst" ] ], "additional_components": [ "C6KSS1", "PF3D7_0607300" ] }, "reaction_10690018": { "compartment": "compartment_17927", "id": "reaction_10690018", "reactome": "R-PFA-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189411" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10690015", "catalyst" ] ], "additional_components": [ "Q8IHU1", "PF3D7_1142400" ] }, "reaction_10690080": { "compartment": "compartment_70101", "id": "reaction_10690080", "reactome": "R-PFA-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190173", "species_10690045" ], "products": [ "species_10690078", "species_29426" ], "modifiers": [], "additional_components": [ "species_216785", "Q8IL68", "PF3D7_1440300", "species_216785", "Q8IL68", "PF3D7_1440300", "species_391232" ] }, "reaction_10690048": { "compartment": "compartment_70101", "id": "reaction_10690048", "reactome": "R-PFA-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_29356", "species_70106", "species_189464" ], "modifiers": [ [ "species_10690045", "catalyst" ] ], "additional_components": [ "species_216785", "Q8IL68", "PF3D7_1440300" ] }, "reaction_10690038": { "compartment": "compartment_70101", "id": "reaction_10690038", "reactome": "R-PFA-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_189455", "species_113528" ], "modifiers": [ [ "species_10690035", "catalyst" ] ], "additional_components": [ "C6KSS1", "PF3D7_0607300" ] }, "reaction_10694949": { "compartment": "compartment_5460", "id": "reaction_10694949", "reactome": "R-PFA-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189444", "species_2162257", "species_113521" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10694946", "catalyst" ] ], "additional_components": [ "PF3D7_0519300" ] }, "reaction_10692756": { "compartment": "compartment_876", "id": "reaction_10692756", "reactome": "R-PFA-917979", "name": "ABCG2 tetramer transports heme from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_71185" ], "products": [ "species_29372", "species_917877", "species_29370" ], "modifiers": [ [ "species_10692753", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690008": { "compartment": "compartment_70101", "id": "reaction_10690008", "reactome": "R-PFA-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_189464" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10690005", "catalyst" ] ], "additional_components": [ "Q8I5V3", "PF3D7_1209600", "CHEBI:36319" ] }, "reaction_10694957": { "compartment": "compartment_5460", "id": "reaction_10694957", "reactome": "R-PFA-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10694954", "catalyst" ] ], "additional_components": [ "PF3D7_1435000" ] }, "reaction_10690028": { "compartment": "compartment_17927", "id": "reaction_10690028", "reactome": "R-PFA-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10690025", "catalyst" ] ], "additional_components": [ "Q8IJC3", "PF3D7_1028100", "species_29386" ] }, "reaction_10690076": { "compartment": "compartment_5460", "id": "reaction_10690076", "reactome": "R-PFA-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_113529", "species_189444" ], "modifiers": [ [ "species_10690073", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "Q8ID58", "PF3D7_1364900" ] }, "reaction_10689488": { "compartment": "compartment_70101", "id": "reaction_10689488", "reactome": "R-PFA-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689484", "species_29438" ], "products": [ "species_10689486" ], "modifiers": [], "additional_components": [ "PF3D7_1451100", "species_29438", "Q8IKW5", "PF3D7_1451100" ] }, "reaction_10701428": { "compartment": "compartment_20699", "id": "reaction_10701428", "reactome": "R-PFA-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696892", "species_10701424" ], "products": [ "species_10701426" ], "modifiers": [], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10701434": { "compartment": "compartment_20699", "id": "reaction_10701434", "reactome": "R-PFA-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701274", "species_10701430" ], "products": [ "species_10701432" ], "modifiers": [], "additional_components": [ "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700" ] }, "reaction_10701439": { "compartment": "compartment_20699", "id": "reaction_10701439", "reactome": "R-PFA-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701213", "species_10701422" ], "products": [ "species_10701424" ], "modifiers": [], "additional_components": [ "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800" ] }, "reaction_10701437": { "compartment": "compartment_20699", "id": "reaction_10701437", "reactome": "R-PFA-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10701426" ], "products": [ "species_29420", "species_10701430" ], "modifiers": [ [ "species_10701426", "catalyst" ] ], "additional_components": [ "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "species_29438", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10701485": { "compartment": "compartment_12045", "id": "reaction_10701485", "reactome": "R-PFA-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10701483", "species_10698587" ], "products": [ "species_10701481" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "C0H5E1", "PF3D7_1326800", "A0A5K1K9E7", "PF3D7_1316800", "O97323", "PF3D7_0320100", "O77313", "PF3D7_0303000", "C0H5E1", "PF3D7_1326800", "A0A5K1K9E7", "PF3D7_1316800", "O77313", "PF3D7_0303000", "O97323", "PF3D7_0320100", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10694883": { "compartment": "compartment_70101", "id": "reaction_10694883", "reactome": "R-PFA-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694861" ], "products": [ "species_10694881" ], "modifiers": [], "additional_components": [ "species_216785", "CHEBI:29034", "Q8IAM8", "PF3D7_0802800", "species_74016", "P62203", "PF14_0323", "Q8IKV9", "PF3D7_1451700", "species_74016", "Q8IKV9", "PF3D7_1451700", "P62203", "PF14_0323", "Q8IAM8", "PF3D7_0802800", "CHEBI:29034", "species_216785" ] }, "reaction_10702926": { "compartment": "compartment_7660", "id": "reaction_10702926", "reactome": "R-PFA-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10702912" ], "products": [ "species_113582", "species_10702923" ], "modifiers": [ [ "species_10692168", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600", "Q8I239", "PF3D7_0110600", "PF3D7_0724600" ] }, "reaction_10701516": { "compartment": "compartment_7660", "id": "reaction_10701516", "reactome": "R-PFA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_29358" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10701513", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10701668": { "compartment": "compartment_70101", "id": "reaction_10701668", "reactome": "R-PFA-8848338", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10701665", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10689972": { "compartment": "compartment_5460", "id": "reaction_10689972", "reactome": "R-PFA-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_31649", "species_188451" ], "modifiers": [ [ "species_10689969", "catalyst" ] ], "additional_components": [ "PF3D7_0306400" ] }, "reaction_10701673": { "compartment": "compartment_70101", "id": "reaction_10701673", "reactome": "R-PFA-8848339", "name": "PNPLA5 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10701670", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10701676": { "compartment": "compartment_70101", "id": "reaction_10701676", "reactome": "R-PFA-8848355", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2534407" ], "products": [ "species_8848337", "species_30209" ], "modifiers": [ [ "species_10701665", "catalyst" ] ], "additional_components": [ "PF3D7_0218600" ] }, "reaction_10697441": { "compartment": "compartment_70101", "id": "reaction_10697441", "reactome": "R-PFA-5682285", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5682283", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5229279" ], "modifiers": [ [ "species_10697438", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693632": { "compartment": "compartment_876", "id": "reaction_10693632", "reactome": "R-PFA-1369052", "name": "ABCAs mediate lipid influx", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_29356", "species_113592" ], "products": [ "species_29372", "species_176478", "species_29370" ], "modifiers": [ [ "species_10693627", "catalyst" ] ], "additional_components": [] }, "reaction_10690928": { "compartment": "compartment_876", "id": "reaction_10690928", "reactome": "R-PFA-266082", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_216762", "species_113592" ], "products": [ "species_29372", "species_29370", "species_171095" ], "modifiers": [ [ "species_10690925", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10690921": { "compartment": "compartment_876", "id": "reaction_10690921", "reactome": "R-PFA-265783", "name": "ABCG5:ABCG8 transports sterols from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_265784", "species_113592" ], "products": [ "species_29372", "species_29370", "species_265781" ], "modifiers": [ [ "species_10690918", "catalyst" ] ], "additional_components": [ "CHEBI:26125", "species_171149", "CHEBI:26125", "species_171149", "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10701647": { "compartment": "compartment_70101", "id": "reaction_10701647", "reactome": "R-PFA-8848053", "name": "ABCA5 transports CHOL from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_8848047" ], "products": [ "species_29372", "species_176478", "species_29370" ], "modifiers": [ [ "species_10701644", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693647": { "compartment": "compartment_70101", "id": "reaction_10693647", "reactome": "R-PFA-1454928", "name": "ABCG4 may mediate cholesterol efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176478", "species_29356", "species_113592" ], "products": [ "species_171149", "species_29372", "species_29370" ], "modifiers": [ [ "species_10693644", "catalyst" ] ], "additional_components": [ "Q8ILJ9", "PF3D7_1426500" ] }, "reaction_10693630": { "compartment": "compartment_876", "id": "reaction_10693630", "reactome": "R-PFA-1369028", "name": "ABCAs mediate lipid efflux", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_176478", "species_113592" ], "products": [ "species_171149", "species_29372", "species_29370" ], "modifiers": [ [ "species_10693627", "catalyst" ] ], "additional_components": [] }, "reaction_10697468": { "compartment": "compartment_2133233", "id": "reaction_10697468", "reactome": "R-PFA-5683714", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5684863" ], "products": [ "species_29372", "species_29370", "species_5684869" ], "modifiers": [ [ "species_10697465", "catalyst" ] ], "additional_components": [ "species_194276", "species_1483256", "species_194276", "species_1483256", "PF3D7_0319700" ] }, "reaction_10696352": { "compartment": "compartment_70101", "id": "reaction_10696352", "reactome": "R-PFA-5227009", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696348", "species_10687881" ], "products": [ "species_10696350" ], "modifiers": [], "additional_components": [ "PF3D7_1121700", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IIE9", "PF3D7_1121700" ] }, "reaction_10693652": { "compartment": "compartment_876", "id": "reaction_10693652", "reactome": "R-PFA-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1131652" ], "products": [ "species_29372", "species_29370", "species_1467459" ], "modifiers": [ [ "species_10693649", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10696331": { "compartment": "compartment_70101", "id": "reaction_10696331", "reactome": "R-PFA-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5223341" ], "products": [ "species_5223344", "species_29372", "species_29370" ], "modifiers": [ [ "species_10696328", "catalyst" ] ], "additional_components": [ "Q8IHR3", "PF3D7_1145500" ] }, "reaction_10693657": { "compartment": "compartment_74000", "id": "reaction_10693657", "reactome": "R-PFA-1467466", "name": "ABCA4 mediates atRAL transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_2466098" ], "products": [ "species_29372", "species_29370", "species_975622" ], "modifiers": [ [ "species_10693654", "catalyst" ] ], "additional_components": [ "PF3D7_0319700" ] }, "reaction_10693640": { "compartment": "compartment_70101", "id": "reaction_10693640", "reactome": "R-PFA-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1454930" ], "products": [ "species_29372", "species_29370", "species_1454919" ], "modifiers": [ [ "species_10693637", "catalyst" ] ], "additional_components": [ "PF3D7_0112200" ] }, "reaction_10697434": { "compartment": "compartment_70101", "id": "reaction_10697434", "reactome": "R-PFA-5682101", "name": "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10697425" ], "products": [ "species_29370", "species_10697431" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "O97278", "PF3D7_0319700", "O97278", "PF3D7_0319700", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10697436": { "compartment": "compartment_12045", "id": "reaction_10697436", "reactome": "R-PFA-5682103", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697421" ], "products": [ "species_10697425" ], "modifiers": [], "additional_components": [ "O97278", "PF3D7_0319700", "O97278", "PF3D7_0319700" ] }, "reaction_10690889": { "compartment": "compartment_984", "id": "reaction_10690889", "reactome": "R-PFA-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_194276" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10690886", "catalyst" ] ], "additional_components": [ "PF3D7_0629300" ] }, "reaction_10692450": { "compartment": "compartment_876", "id": "reaction_10692450", "reactome": "R-PFA-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10692447", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692436": { "compartment": "compartment_876", "id": "reaction_10692436", "reactome": "R-PFA-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10692433", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800", "C0H4T7", "PF3D7_0810400" ] }, "reaction_10692452": { "compartment": "compartment_876", "id": "reaction_10692452", "reactome": "R-PFA-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10692447", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692443": { "compartment": "compartment_876", "id": "reaction_10692443", "reactome": "R-PFA-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10692433", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800", "C0H4T7", "PF3D7_0810400" ] }, "reaction_10692441": { "compartment": "compartment_876", "id": "reaction_10692441", "reactome": "R-PFA-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10692438", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10692445": { "compartment": "compartment_876", "id": "reaction_10692445", "reactome": "R-PFA-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10692438", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691955": { "compartment": "compartment_876", "id": "reaction_10691955", "reactome": "R-PFA-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691952", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691777": { "compartment": "compartment_876", "id": "reaction_10691777", "reactome": "R-PFA-432065", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10691774", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691802": { "compartment": "compartment_70101", "id": "reaction_10691802", "reactome": "R-PFA-432232", "name": "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10691795" ], "products": [ "species_29370", "species_10691799" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400", "C0H4T7", "PF3D7_0810400", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10703161": { "compartment": "compartment_70101", "id": "reaction_10703161", "reactome": "R-PFA-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10689282" ], "products": [ "species_10689284" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "species_30389" ] }, "reaction_10691769": { "compartment": "compartment_876", "id": "reaction_10691769", "reactome": "R-PFA-432054", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10689288": { "compartment": "compartment_70101", "id": "reaction_10689288", "reactome": "R-PFA-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689284" ], "products": [ "species_10689286", "species_10689280" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7KQK0", "PF3D7_1223100", "species_30389", "species_30389", "Q7KQK0", "PF3D7_1223100", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10691784": { "compartment": "compartment_876", "id": "reaction_10691784", "reactome": "R-PFA-432067", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10691781", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691757": { "compartment": "compartment_876", "id": "reaction_10691757", "reactome": "R-PFA-432010", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691767": { "compartment": "compartment_876", "id": "reaction_10691767", "reactome": "R-PFA-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10691764", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10691791": { "compartment": "compartment_876", "id": "reaction_10691791", "reactome": "R-PFA-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10691788", "catalyst" ] ], "additional_components": [ "Q8II36", "PF3D7_1132800" ] }, "reaction_10696562": { "compartment": "compartment_70101", "id": "reaction_10696562", "reactome": "R-PFA-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10696559", "catalyst" ] ], "additional_components": [ "PF3D7_1304200.2" ] }, "reaction_10696578": { "compartment": "compartment_70101", "id": "reaction_10696578", "reactome": "R-PFA-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696575", "catalyst" ] ], "additional_components": [ "PF3D7_0107700" ] }, "reaction_10696554": { "compartment": "compartment_70101", "id": "reaction_10696554", "reactome": "R-PFA-5336453", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696551", "catalyst" ] ], "additional_components": [ "A0A144A2U1", "PF3D7_1467000", "Q8IBA9", "PF3D7_1467000" ] }, "reaction_10696573": { "compartment": "compartment_70101", "id": "reaction_10696573", "reactome": "R-PFA-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10696570", "catalyst" ] ], "additional_components": [ "PF3D7_0107700" ] }, "reaction_10693563": { "compartment": "compartment_70101", "id": "reaction_10693563", "reactome": "R-PFA-1247649", "name": "AQP1 tetramer transports CO2 from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113528" ], "products": [ "species_1237009" ], "modifiers": [ [ "species_10691754", "catalyst" ] ], "additional_components": [ "C0H4T7", "PF3D7_0810400" ] }, "reaction_10691843": { "compartment": "compartment_876", "id": "reaction_10691843", "reactome": "R-PFA-435349", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_435347" ], "products": [ "species_70106", "species_71067" ], "modifiers": [ [ "species_10691840", "catalyst" ] ], "additional_components": [ "PF3D7_0523800" ] }, "reaction_10691859": { "compartment": "compartment_876", "id": "reaction_10691859", "reactome": "R-PFA-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10691856", "catalyst" ] ], "additional_components": [ "PF3D7_1439000" ] }, "reaction_10691873": { "compartment": "compartment_876", "id": "reaction_10691873", "reactome": "R-PFA-442422", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10691870", "catalyst" ] ], "additional_components": [ "C6KST8", "PF3D7_0609100" ] }, "reaction_10691851": { "compartment": "compartment_20699", "id": "reaction_10691851", "reactome": "R-PFA-437136", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10691848", "catalyst" ] ], "additional_components": [ "PF3D7_0715900" ] }, "reaction_10691838": { "compartment": "compartment_172574", "id": "reaction_10691838", "reactome": "R-PFA-435171", "name": "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_445829" ], "products": [ "species_445832", "species_1470067" ], "modifiers": [ [ "species_10691835", "catalyst" ] ], "additional_components": [ "species_216785", "species_71067", "species_1981162", "species_216785", "species_1981162", "species_71067", "PF3D7_0523800" ] }, "reaction_10691830": { "compartment": "compartment_876", "id": "reaction_10691830", "reactome": "R-PFA-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_446589" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10691827", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:641", "CHEBI:6801", "CHEBI:16737", "CHEBI:8428", "CHEBI:42820", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "CHEBI:6801", "O96209", "PF3D7_0212800" ] }, "reaction_10692562": { "compartment": "compartment_876", "id": "reaction_10692562", "reactome": "R-PFA-561072", "name": "OCT3 mediates renal uptake of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549255" ], "products": [ "species_549326" ], "modifiers": [ [ "species_10692535", "catalyst" ] ], "additional_components": [ "CHEBI:47781", "CHEBI:8428", "CHEBI:42820", "CHEBI:47499", "CHEBI:641", "CHEBI:46020", "CHEBI:46631", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:47499", "CHEBI:47781", "CHEBI:641", "CHEBI:46631", "PF3D7_1203400" ] }, "reaction_10692533": { "compartment": "compartment_876", "id": "reaction_10692533", "reactome": "R-PFA-549297", "name": "SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164988", "species_74113" ], "products": [ "species_30235", "species_83910" ], "modifiers": [ [ "species_10692530", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10692516": { "compartment": "compartment_876", "id": "reaction_10692516", "reactome": "R-PFA-549129", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549264" ], "products": [ "species_549250" ], "modifiers": [ [ "species_10692513", "catalyst" ] ], "additional_components": [ "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "CHEBI:18295", "species_353560", "species_6798162", "CHEBI:16797", "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "CHEBI:16797", "species_6798162", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "CHEBI:18295", "species_353560", "species_209789", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692538": { "compartment": "compartment_876", "id": "reaction_10692538", "reactome": "R-PFA-549304", "name": "OCT3 mediates renal clearance of organic cations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549326" ], "products": [ "species_549255" ], "modifiers": [ [ "species_10692535", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:47499", "CHEBI:47781", "CHEBI:641", "CHEBI:46631", "CHEBI:47781", "CHEBI:8428", "CHEBI:42820", "CHEBI:47499", "CHEBI:641", "CHEBI:46020", "CHEBI:46631", "PF3D7_1203400" ] }, "reaction_10692553": { "compartment": "compartment_876", "id": "reaction_10692553", "reactome": "R-PFA-561054", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549266" ], "products": [ "species_549237" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "CHEBI:16797", "CHEBI:16737", "species_6798162", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "CHEBI:18295", "CHEBI:31941", "species_209789", "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "CHEBI:18295", "species_6798162", "CHEBI:16797", "species_209914", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692521": { "compartment": "compartment_876", "id": "reaction_10692521", "reactome": "R-PFA-549241", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549261", "species_74113" ], "products": [ "species_83910", "species_549260" ], "modifiers": [ [ "species_10692518", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10692575": { "compartment": "compartment_876", "id": "reaction_10692575", "reactome": "R-PFA-597628", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_597604", "species_70106" ], "products": [ "species_351626", "species_597623" ], "modifiers": [ [ "species_10692572", "catalyst" ] ], "additional_components": [ "PF3D7_0516500" ] }, "reaction_10692540": { "compartment": "compartment_876", "id": "reaction_10692540", "reactome": "R-PFA-549322", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549250" ], "products": [ "species_549264" ], "modifiers": [ [ "species_10692513", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "CHEBI:16797", "species_6798162", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "CHEBI:18295", "species_353560", "species_209789", "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "CHEBI:18295", "species_353560", "species_6798162", "CHEBI:16797", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692524": { "compartment": "compartment_876", "id": "reaction_10692524", "reactome": "R-PFA-549279", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549237" ], "products": [ "species_549266" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_380873", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "CHEBI:18295", "species_6798162", "CHEBI:16797", "species_209914", "species_380873", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "CHEBI:16797", "CHEBI:16737", "species_6798162", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "CHEBI:18295", "CHEBI:31941", "species_209789", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692560": { "compartment": "compartment_876", "id": "reaction_10692560", "reactome": "R-PFA-561059", "name": "OAT2 and OAT4 mediate transport of sulphate conjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561071" ], "products": [ "species_561062", "species_561075" ], "modifiers": [ [ "species_10692557", "catalyst" ] ], "additional_components": [ "CHEBI:16814", "CHEBI:17474", "CHEBI:17474", "CHEBI:16814", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692551": { "compartment": "compartment_876", "id": "reaction_10692551", "reactome": "R-PFA-561041", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561049" ], "products": [ "species_561078", "species_561075" ], "modifiers": [ [ "species_10692548", "catalyst" ] ], "additional_components": [ "CHEBI:104011", "CHEBI:2453", "CHEBI:2453", "CHEBI:104011", "Q8I611", "PF3D7_1203400" ] }, "reaction_10692567": { "compartment": "compartment_876", "id": "reaction_10692567", "reactome": "R-PFA-561253", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_429056" ], "products": [ "species_373863", "species_30034" ], "modifiers": [ [ "species_10692564", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10691904": { "compartment": "compartment_876", "id": "reaction_10691904", "reactome": "R-PFA-443997", "name": "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935", "species_74113" ], "products": [ "species_209789", "species_83910" ], "modifiers": [ [ "species_10691901", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691015": { "compartment": "compartment_876", "id": "reaction_10691015", "reactome": "R-PFA-351963", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266029" ], "products": [ "species_29424" ], "modifiers": [ [ "species_10691012", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691076": { "compartment": "compartment_984", "id": "reaction_10691076", "reactome": "R-PFA-379393", "name": "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_74113" ], "products": [ "species_83910", "species_159362" ], "modifiers": [ [ "species_10691017", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691913": { "compartment": "compartment_70101", "id": "reaction_10691913", "reactome": "R-PFA-444007", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352003", "species_74113" ], "products": [ "species_352011", "species_83910", "species_352022" ], "modifiers": [ [ "species_10691910", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10691023": { "compartment": "compartment_876", "id": "reaction_10691023", "reactome": "R-PFA-352029", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352007", "species_74113" ], "products": [ "species_351982", "species_83910", "species_352022" ], "modifiers": [ [ "species_10690400", "catalyst" ] ], "additional_components": [ "CHEBI:16958", "species_352011", "CHEBI:17750", "CHEBI:48950", "CHEBI:48950", "CHEBI:16958", "CHEBI:17750", "species_352011", "PF3D7_0209600" ] }, "reaction_10691020": { "compartment": "compartment_876", "id": "reaction_10691020", "reactome": "R-PFA-351987", "name": "SLC6A6-mediated uptake of taurine and beta-alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352024", "species_74113" ], "products": [ "species_83910", "species_352019", "species_352022" ], "modifiers": [ [ "species_10691017", "catalyst" ] ], "additional_components": [ "CHEBI:16958", "CHEBI:15891", "CHEBI:16958", "CHEBI:15891", "PF3D7_0209600" ] }, "reaction_10691058": { "compartment": "compartment_876", "id": "reaction_10691058", "reactome": "R-PFA-375473", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375458", "species_74113" ], "products": [ "species_375481", "species_83910" ], "modifiers": [ [ "species_10691055", "catalyst" ] ], "additional_components": [ "species_29432", "CHEBI:57912", "species_29472", "CHEBI:58045", "species_111707", "species_200736", "species_29424", "CHEBI:57427", "species_379705", "CHEBI:58315", "species_29502", "CHEBI:57762", "species_29424", "species_29472", "CHEBI:58315", "species_200736", "CHEBI:57427", "species_379705", "CHEBI:58045", "CHEBI:57762", "species_29432", "species_111707", "CHEBI:57912", "species_29502", "PF3D7_0209600" ] }, "reaction_10691921": { "compartment": "compartment_876", "id": "reaction_10691921", "reactome": "R-PFA-444100", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538", "species_352022" ], "modifiers": [ [ "species_10690402", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691063": { "compartment": "compartment_876", "id": "reaction_10691063", "reactome": "R-PFA-375487", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_375468", "species_74113" ], "products": [ "species_83910", "species_375459", "species_352022" ], "modifiers": [ [ "species_10691060", "catalyst" ] ], "additional_components": [ "species_29432", "CHEBI:57912", "CHEBI:58045", "CHEBI:32513", "species_200736", "species_29424", "species_29468", "CHEBI:16958", "species_1131871", "species_111707", "CHEBI:57427", "species_379705", "CHEBI:57762", "species_200736", "CHEBI:57762", "CHEBI:32513", "species_1131871", "species_29424", "CHEBI:57427", "species_379705", "CHEBI:58045", "CHEBI:16958", "species_29432", "species_111707", "species_29468", "CHEBI:57912", "PF3D7_0209600" ] }, "reaction_10691028": { "compartment": "compartment_876", "id": "reaction_10691028", "reactome": "R-PFA-352052", "name": "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538" ], "modifiers": [ [ "species_10691025", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10691930": { "compartment": "compartment_876", "id": "reaction_10691930", "reactome": "R-PFA-444120", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_266029", "species_74113" ], "products": [ "species_83910", "species_352022", "species_29424" ], "modifiers": [ [ "species_10691927", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10691033": { "compartment": "compartment_876", "id": "reaction_10691033", "reactome": "R-PFA-352059", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352051", "species_74113" ], "products": [ "species_83910", "species_352048" ], "modifiers": [ [ "species_10691030", "catalyst" ] ], "additional_components": [ "species_29432", "species_29472", "CHEBI:58045", "species_379717", "CHEBI:57926", "species_111707", "species_200736", "species_29642", "CHEBI:57427", "species_379705", "CHEBI:18240", "CHEBI:57762", "species_29472", "species_379717", "CHEBI:57926", "species_200736", "CHEBI:57427", "species_379705", "CHEBI:18240", "CHEBI:58045", "CHEBI:57762", "species_29432", "species_29642", "species_111707", "PF3D7_0209600" ] }, "reaction_10691948": { "compartment": "compartment_984", "id": "reaction_10691948", "reactome": "R-PFA-444433", "name": "Cho transports from the extracellular space to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264638" ], "products": [ "species_264618" ], "modifiers": [ [ "species_10691945", "catalyst" ] ], "additional_components": [ "Q8ILE6", "PF3D7_1431900" ] }, "reaction_10702179": { "compartment": "compartment_70101", "id": "reaction_10702179", "reactome": "R-PFA-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_2162265", "species_71285" ], "modifiers": [ [ "species_10702176", "catalyst" ] ], "additional_components": [ "PF3D7_1241600" ] }, "reaction_10691543": { "compartment": "compartment_876", "id": "reaction_10691543", "reactome": "R-PFA-427605", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10691540", "catalyst" ] ], "additional_components": [ "Q8IDS7", "PF3D7_1340900" ] }, "reaction_10692626": { "compartment": "compartment_20699", "id": "reaction_10692626", "reactome": "R-PFA-742345", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742368" ], "products": [ "species_205683" ], "modifiers": [ [ "species_10692623", "catalyst" ] ], "additional_components": [ "PF3D7_0212000" ] }, "reaction_10692613": { "compartment": "compartment_20699", "id": "reaction_10692613", "reactome": "R-PFA-727807", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727810", "species_4085435" ], "products": [ "species_727815", "species_109395" ], "modifiers": [ [ "species_10692610", "catalyst" ] ], "additional_components": [ "PF3D7_0505300" ] }, "reaction_10692618": { "compartment": "compartment_20699", "id": "reaction_10692618", "reactome": "R-PFA-735702", "name": "SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735698", "species_735692" ], "products": [ "species_109402", "species_735691" ], "modifiers": [ [ "species_10692615", "catalyst" ] ], "additional_components": [ "species_735700", "species_735682", "species_735682", "species_735700", "PF3D7_0505300" ] }, "reaction_10688817": { "compartment": "compartment_70101", "id": "reaction_10688817", "reactome": "R-PFA-109536", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737" ], "products": [ "species_179743" ], "modifiers": [ [ "species_10688812", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:16335", "CHEBI:17562", "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692593": { "compartment": "compartment_70101", "id": "reaction_10692593", "reactome": "R-PFA-727749", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727782" ], "products": [ "species_727746" ], "modifiers": [ [ "species_10692590", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17596", "CHEBI:16704", "CHEBI:16750", "CHEBI:17562", "CHEBI:17748", "species_5635947", "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "species_5635947", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10689584": { "compartment": "compartment_70616", "id": "reaction_10689584", "reactome": "R-PFA-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10689581", "catalyst" ] ], "additional_components": [ "Q8IJ34", "PF3D7_1037300", "Q8IBF2", "PF3D7_1037300" ] }, "reaction_10688810": { "compartment": "compartment_70101", "id": "reaction_10688810", "reactome": "R-PFA-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10688805", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:16040", "CHEBI:16235", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17821", "species_83962", "CHEBI:17562", "species_5635947", "species_29850", "CHEBI:17596", "CHEBI:16750", "CHEBI:16235", "CHEBI:16704", "CHEBI:17748", "species_29850", "CHEBI:16335", "CHEBI:17821", "species_83962", "species_5635947", "CHEBI:17562", "CHEBI:16040", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10688808": { "compartment": "compartment_70101", "id": "reaction_10688808", "reactome": "R-PFA-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10688805", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16235", "CHEBI:16704", "CHEBI:17748", "species_29850", "CHEBI:16335", "CHEBI:17821", "species_83962", "species_5635947", "CHEBI:17562", "CHEBI:16040", "CHEBI:16335", "CHEBI:16040", "CHEBI:16235", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17821", "species_83962", "CHEBI:17562", "species_5635947", "species_29850", "Q8IDM6", "PF3D7_1469400", "Q8IKE3", "PF3D7_1469400" ] }, "reaction_10692584": { "compartment": "compartment_70101", "id": "reaction_10692584", "reactome": "R-PFA-727740", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727774" ], "products": [ "species_727737" ], "modifiers": [ [ "species_10692581", "catalyst" ] ], "additional_components": [ "species_209789", "CHEBI:16335", "species_209914", "species_380873", "CHEBI:28918", "species_380873", "CHEBI:28918", "CHEBI:16335", "species_209914", "species_209789", "Q8IKE3", "PF3D7_1469400", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10688815": { "compartment": "compartment_70101", "id": "reaction_10688815", "reactome": "R-PFA-109534", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179743" ], "products": [ "species_179737" ], "modifiers": [ [ "species_10688812", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:17562", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "CHEBI:17748", "CHEBI:16335", "CHEBI:17562", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692605": { "compartment": "compartment_70101", "id": "reaction_10692605", "reactome": "R-PFA-727768", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727737" ], "products": [ "species_727774" ], "modifiers": [ [ "species_10692581", "catalyst" ] ], "additional_components": [ "species_380873", "CHEBI:28918", "CHEBI:16335", "species_209914", "species_209789", "species_209789", "CHEBI:16335", "species_209914", "species_380873", "CHEBI:28918", "Q8IKE3", "PF3D7_1469400", "Q8IDM6", "PF3D7_1469400" ] }, "reaction_10692601": { "compartment": "compartment_20699", "id": "reaction_10692601", "reactome": "R-PFA-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10692598", "catalyst" ] ], "additional_components": [ "PF3D7_1036800" ] }, "reaction_10703281": { "compartment": "compartment_70101", "id": "reaction_10703281", "reactome": "R-PFA-8981574", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10691617": { "compartment": "compartment_876", "id": "reaction_10691617", "reactome": "R-PFA-428779", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428819" ], "products": [ "species_428802" ], "modifiers": [ [ "species_10691614", "catalyst" ] ], "additional_components": [ "species_70115", "species_29532", "species_70115", "species_29532", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692151": { "compartment": "compartment_70101", "id": "reaction_10692151", "reactome": "R-PFA-450092", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692147" ], "products": [ "species_113592", "species_10692145" ], "modifiers": [], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "species_29358", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10696565": { "compartment": "compartment_70101", "id": "reaction_10696565", "reactome": "R-PFA-5339524", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10692145", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692149": { "compartment": "compartment_70101", "id": "reaction_10692149", "reactome": "R-PFA-450088", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10692145" ], "products": [ "species_10692147" ], "modifiers": [], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500", "species_29358" ] }, "reaction_10703268": { "compartment": "compartment_70101", "id": "reaction_10703268", "reactome": "R-PFA-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703265", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10692154": { "compartment": "compartment_70101", "id": "reaction_10692154", "reactome": "R-PFA-450095", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10691626": { "compartment": "compartment_876", "id": "reaction_10691626", "reactome": "R-PFA-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10691623", "catalyst" ] ], "additional_components": [ "species_70115", "species_30034", "species_29532", "species_70115", "species_30034", "species_29532", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10703279": { "compartment": "compartment_70101", "id": "reaction_10703279", "reactome": "R-PFA-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703276", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10703263": { "compartment": "compartment_70101", "id": "reaction_10703263", "reactome": "R-PFA-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10703260", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10698311": { "compartment": "compartment_70101", "id": "reaction_10698311", "reactome": "R-PFA-5690873", "name": "ACO1 binds 4Fe-4S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690881", "species_10698307" ], "products": [ "species_10698309" ], "modifiers": [], "additional_components": [ "PF3D7_1342100", "Q8IDR8", "PF3D7_1342100" ] }, "reaction_10692748": { "compartment": "compartment_74700", "id": "reaction_10692748", "reactome": "R-PFA-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_70106", "species_113592" ], "products": [ "species_29372", "species_29370", "species_74722" ], "modifiers": [ [ "species_10688527", "catalyst" ] ], "additional_components": [ "C0H4P0", "PF3D7_0721900", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8IDF7", "PF3D7_1354400", "Q8IKJ0", "PF3D7_1464700", "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10698318": { "compartment": "compartment_70101", "id": "reaction_10698318", "reactome": "R-PFA-5690911", "name": "ACO1:4Fe-4S isomerises CIT to ISCIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76190" ], "products": [ "species_389545" ], "modifiers": [ [ "species_10698309", "catalyst" ] ], "additional_components": [ "Q8IDR8", "PF3D7_1342100" ] }, "reaction_10698349": { "compartment": "compartment_70101", "id": "reaction_10698349", "reactome": "R-PFA-5691108", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698313", "species_10686740" ], "products": [ "species_10698340" ], "modifiers": [ [ "species_10698346", "catalyst" ] ], "additional_components": [ "PF3D7_1342100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1342100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "Q8IEI4", "PF3D7_1313000" ] }, "reaction_10692878": { "compartment": "compartment_70101", "id": "reaction_10692878", "reactome": "R-PFA-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10692873" ], "products": [ "species_10692875", "species_29370" ], "modifiers": [ [ "species_10692873", "catalyst" ] ], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "Q8IIC9", "PF3D7_1123400", "species_29420", "Q8IFN9", "PF3D7_0422700", "Q8IBJ9", "PF3D7_0725200", "Q8I2Q1", "PF3D7_0925800", "Q8IE18", "PF3D7_1330800", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500" ] }, "reaction_10697478": { "compartment": "compartment_7660", "id": "reaction_10697478", "reactome": "R-PFA-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697474" ], "products": [ "species_10697476" ], "modifiers": [], "additional_components": [ "PF3D7_1423600", "Q8ILL6", "PF3D7_1423600" ] }, "reaction_10697486": { "compartment": "compartment_7660", "id": "reaction_10697486", "reactome": "R-PFA-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10697476" ], "products": [ "species_113582", "species_10697483" ], "modifiers": [ [ "species_10697476", "catalyst" ] ], "additional_components": [ "Q8ILL6", "PF3D7_1423600", "PF3D7_1423600", "Q8ILL6", "PF3D7_1423600" ] }, "reaction_10689771": { "compartment": "compartment_70101", "id": "reaction_10689771", "reactome": "R-PFA-174159", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10689766" ], "products": [ "species_10689768" ], "modifiers": [ [ "species_10689762", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000" ] }, "reaction_10689773": { "compartment": "compartment_70101", "id": "reaction_10689773", "reactome": "R-PFA-174203", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689768" ], "products": [ "species_10686740", "species_10689729", "species_10689762" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1026400", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "Q8IAU5", "PF3D7_0811000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10686942": { "compartment": "compartment_7660", "id": "reaction_10686942", "reactome": "R-PFA-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_10686458", "species_30185", "species_29892", "species_29604" ], "products": [ "species_10686939" ], "modifiers": [ [ "species_10686433", "catalyst" ] ], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10686461": { "compartment": "compartment_7660", "id": "reaction_10686461", "reactome": "R-PFA-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686456", "species_30595" ], "products": [ "species_10686458", "species_10686452" ], "modifiers": [ [ "species_10686456", "catalyst" ] ], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10688544": { "compartment": "compartment_13231", "id": "reaction_10688544", "reactome": "R-PFA-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688540" ], "products": [ "species_10688542" ], "modifiers": [], "additional_components": [ "PF3D7_0704700", "PF3D7_0704700" ] }, "reaction_10688548": { "compartment": "compartment_70101", "id": "reaction_10688548", "reactome": "R-PFA-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688546" ], "products": [ "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IC23", "PF3D7_0704700", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10689779": { "compartment": "compartment_13231", "id": "reaction_10689779", "reactome": "R-PFA-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689722" ], "products": [ "species_10689741" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900" ] }, "reaction_10689952": { "compartment": "compartment_7660", "id": "reaction_10689952", "reactome": "R-PFA-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10689775" ], "products": [ "species_113582", "species_10689777" ], "modifiers": [ [ "species_10686575", "catalyst" ] ], "additional_components": [ "PF3D7_1026400", "PF3D7_1026400", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10689724": { "compartment": "compartment_70101", "id": "reaction_10689724", "reactome": "R-PFA-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687085", "species_10689716" ], "products": [ "species_10689722" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10696324": { "compartment": "compartment_13231", "id": "reaction_10696324", "reactome": "R-PFA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10695746", "catalyst" ] ], "additional_components": [ "O77317", "PF3D7_0303200" ] }, "reaction_10694673": { "compartment": "compartment_7660", "id": "reaction_10694673", "reactome": "R-PFA-2288097", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694648", "species_10694615" ], "products": [ "species_10694667" ], "modifiers": [ [ "species_10694671", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600" ] }, "reaction_10694709": { "compartment": "compartment_7660", "id": "reaction_10694709", "reactome": "R-PFA-2301205", "name": "SETD8 monomethylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10694658" ], "products": [ "species_77502", "species_10694654" ], "modifiers": [ [ "species_10694706", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067", "PF3D7_0403900" ] }, "reaction_10694661": { "compartment": "compartment_7660", "id": "reaction_10694661", "reactome": "R-PFA-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694654", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10694658" ], "modifiers": [ [ "species_10694654", "catalyst" ] ], "additional_components": [ "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067", "Q8IIV2", "PF3D7_1105000", "species_71067" ] }, "reaction_10694699": { "compartment": "compartment_7660", "id": "reaction_10694699", "reactome": "R-PFA-2294580", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10694683" ], "products": [ "species_113582", "species_10694696" ], "modifiers": [ [ "species_10694683", "catalyst" ] ], "additional_components": [ "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000", "Q8IED2", "MAL13P1.96", "Q8IKZ3", "PF3D7_1448200", "Q8I413", "PF3D7_0509100", "O96140", "PF3D7_0204000", "Q8II07", "PF3D7_1135600", "Q8IIV2", "PF3D7_1105000" ] }, "reaction_10694841": { "compartment": "compartment_70101", "id": "reaction_10694841", "reactome": "R-PFA-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10694807" ], "products": [ "species_10694797", "species_29370" ], "modifiers": [ [ "species_10694838", "catalyst" ] ], "additional_components": [ "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8I413", "PF3D7_0509100", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I413", "PF3D7_0509100", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200", "Q8IDR5", "PF3D7_1342400" ] }, "reaction_10694809": { "compartment": "compartment_70101", "id": "reaction_10694809", "reactome": "R-PFA-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694797", "species_29356" ], "products": [ "species_29372", "species_10694807" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100", "Q8I413", "PF3D7_0509100", "Q8I2Y3", "PF3D7_0917000", "C0H598", "PF3D7_1304000", "Q8I413", "PF3D7_0509100", "Q8IED2", "MAL13P1.96", "C6S3H2", "PF3D7_1403100" ] }, "reaction_10689490": { "compartment": "compartment_13231", "id": "reaction_10689490", "reactome": "R-PFA-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687093" ], "products": [ "species_10687099" ], "modifiers": [], "additional_components": [ "Q8IC23", "PF3D7_0704700", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8ILC4", "PF3D7_1433900" ] }, "reaction_10687095": { "compartment": "compartment_70101", "id": "reaction_10687095", "reactome": "R-PFA-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687085", "species_10687091" ], "products": [ "species_10687093" ], "modifiers": [], "additional_components": [ "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900", "Q8IC23", "PF3D7_0704700", "Q8IC23", "PF3D7_0704700", "Q8ILC4", "PF3D7_1433900", "Q8IJQ1", "PF3D7_1433900" ] }, "reaction_10689368": { "compartment": "compartment_7660", "id": "reaction_10689368", "reactome": "R-PFA-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686939" ], "products": [ "species_113656", "species_10686433" ], "modifiers": [], "additional_components": [ "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900" ] }, "reaction_10686946": { "compartment": "compartment_7660", "id": "reaction_10686946", "reactome": "R-PFA-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686452", "species_68419" ], "products": [ "species_10686454" ], "modifiers": [], "additional_components": [ "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10686463": { "compartment": "compartment_7660", "id": "reaction_10686463", "reactome": "R-PFA-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686454", "species_10686433" ], "products": [ "species_10686456" ], "modifiers": [], "additional_components": [ "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IKK3", "PF3D7_1463300", "Q7KQM1", "PF14_0366", "C0H531", "PF3D7_0910900", "Q9U0H1", "PF3D7_0411900", "Q8IEN4", "PF3D7_1308100", "C6KTD8", "PF3D7_0630300", "Q8I579", "PF3D7_1234300" ] }, "reaction_10702067": { "compartment": "compartment_70101", "id": "reaction_10702067", "reactome": "R-PFA-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702063", "species_10702058" ], "products": [ "species_10702065" ], "modifiers": [], "additional_components": [ "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200" ] }, "reaction_10702090": { "compartment": "compartment_70101", "id": "reaction_10702090", "reactome": "R-PFA-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686740", "species_10702065" ], "products": [ "species_10702087" ], "modifiers": [ [ "species_10702065", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200", "O77328", "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "O77328", "PF3D7_0309200" ] }, "reaction_10702092": { "compartment": "compartment_70101", "id": "reaction_10702092", "reactome": "R-PFA-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702087" ], "products": [ "species_10702058", "species_10686740" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "O77328", "PF3D7_0309200", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8ID38", "PF3D7_1367000", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10690786": { "compartment": "compartment_70101", "id": "reaction_10690786", "reactome": "R-PFA-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10690778" ], "products": [ "species_29420", "species_10690709" ], "modifiers": [ [ "species_10690783", "catalyst" ] ], "additional_components": [ "Q8I1S0", "PF3D7_0416800", "species_29420", "Q8I1S0", "PF3D7_0416800", "species_29438", "PF3D7_1116400" ] }, "reaction_10698657": { "compartment": "compartment_12045", "id": "reaction_10698657", "reactome": "R-PFA-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690764", "species_10690794", "species_10690709" ], "products": [ "species_10690766" ], "modifiers": [], "additional_components": [ "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29438", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698560": { "compartment": "compartment_13959", "id": "reaction_10698560", "reactome": "R-PFA-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10698553" ], "products": [ "species_10698557", "species_29420" ], "modifiers": [ [ "species_10698553", "catalyst" ] ], "additional_components": [ "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100" ] }, "reaction_10701589": { "compartment": "compartment_6791047", "id": "reaction_10701589", "reactome": "R-PFA-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701211", "species_10701585" ], "products": [ "species_10701587" ], "modifiers": [], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "PF3D7_0323100", "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438" ] }, "reaction_10698660": { "compartment": "compartment_70101", "id": "reaction_10698660", "reactome": "R-PFA-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690766" ], "products": [ "species_10690764", "species_29372", "species_10690794", "species_10690778" ], "modifiers": [ [ "species_10690766", "catalyst" ] ], "additional_components": [ "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29420", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698616": { "compartment": "compartment_6791047", "id": "reaction_10698616", "reactome": "R-PFA-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10698612" ], "products": [ "species_10698614" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "O97323", "PF3D7_0320100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IJ69", "PF3D7_1034000", "O97323", "PF3D7_0320100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IJ69", "PF3D7_1034000", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701592": { "compartment": "compartment_6791047", "id": "reaction_10701592", "reactome": "R-PFA-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701587" ], "products": [ "species_10698448", "species_10701585" ], "modifiers": [ [ "species_10701587", "catalyst" ] ], "additional_components": [ "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "PF3D7_0323100", "O97299", "PF3D7_0323100", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438" ] }, "reaction_10698620": { "compartment": "compartment_13959", "id": "reaction_10698620", "reactome": "R-PFA-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698508", "species_10698551", "species_10698448" ], "products": [ "species_10698553" ], "modifiers": [], "additional_components": [ "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "species_29420", "A0A5K1K8H7", "PF3D7_0513800", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I5B3", "PF3D7_1230700", "O96221", "PF3D7_0214100", "Q8IAY0", "PF3D7_0814400", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100" ] }, "reaction_10694722": { "compartment": "compartment_5460", "id": "reaction_10694722", "reactome": "R-PFA-2395512", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694718", "species_10693606" ], "products": [ "species_10693598", "species_113529", "species_10694720" ], "modifiers": [], "additional_components": [ "species_31649", "Q8IHW9", "PF3D7_1139700", "Q8I5R0", "PF3D7_1214600", "CHEBI:33737", "CHEBI:33738", "Q8I5R0", "PF3D7_1214600", "species_29386", "Q8IHW9", "PF3D7_1139700" ] }, "reaction_10694724": { "compartment": "compartment_5460", "id": "reaction_10694724", "reactome": "R-PFA-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_10694720", "species_113600" ], "products": [ "species_10694718", "species_113563" ], "modifiers": [], "additional_components": [ "species_29386", "Q8IHW9", "PF3D7_1139700", "species_31649", "Q8IHW9", "PF3D7_1139700" ] }, "reaction_10695704": { "compartment": "compartment_7660", "id": "reaction_10695704", "reactome": "R-PFA-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10694930" ], "products": [ "species_10695702", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695676": { "compartment": "compartment_7660", "id": "reaction_10695676", "reactome": "R-PFA-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695666" ], "products": [ "species_10695674", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1360700", "Q8I444", "PF3D7_0505800", "A0A5K1K9G1", "PF3D7_1360700", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10703252": { "compartment": "compartment_984", "id": "reaction_10703252", "reactome": "R-PFA-8979996", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10703249", "catalyst" ] ], "additional_components": [] }, "reaction_10688609": { "compartment": "compartment_70101", "id": "reaction_10688609", "reactome": "R-PFA-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_75970", "species_73473" ], "products": [ "species_76114", "species_29360" ], "modifiers": [ [ "species_10688606", "catalyst" ] ], "additional_components": [ "Q8IIL4", "PF3D7_1114800", "Q8I5P5", "PF3D7_1216200" ] }, "reaction_10702964": { "compartment": "compartment_5460", "id": "reaction_10702964", "reactome": "R-PFA-8878654", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878649", "species_113521" ], "products": [ "species_113548", "species_8934414" ], "modifiers": [ [ "species_10702961", "catalyst" ] ], "additional_components": [ "PF3D7_0208400" ] }, "reaction_10688574": { "compartment": "compartment_12045", "id": "reaction_10688574", "reactome": "R-PFA-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_426755", "species_76194" ], "modifiers": [ [ "species_10688571", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700", "Q8IL28", "PF3D7_1444300" ] }, "reaction_10699324": { "compartment": "compartment_70101", "id": "reaction_10699324", "reactome": "R-PFA-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10699321", "catalyst" ] ], "additional_components": [ "Q8IAY0", "PF3D7_0814400" ] }, "reaction_10692323": { "compartment": "compartment_876", "id": "reaction_10692323", "reactome": "R-PFA-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692305" ], "products": [ "species_10692321" ], "modifiers": [], "additional_components": [ "Q8IBM9", "PF3D7_0722400", "Q7KQL9", "PF14_0425", "Q8I509", "PF3D7_1242000", "Q8I563", "PF3D7_1448600", "Q8IKY7", "PF3D7_1448600", "O96268", "PF3D7_0219100", "Q7KQL9", "PF14_0425", "Q8IBM9", "PF3D7_0722400", "Q8I509", "PF3D7_1242000", "O96268", "PF3D7_0219100", "Q8IKY7", "PF3D7_1448600", "Q8I563", "PF3D7_1448600" ] }, "reaction_10692394": { "compartment": "compartment_70101", "id": "reaction_10692394", "reactome": "R-PFA-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692370" ], "products": [ "species_10692392" ], "modifiers": [], "additional_components": [ "Q8I2G8", "PF3D7_0935200", "C6KSX9", "PF3D7_0935200", "Q8IFP3", "PF3D7_0903700", "Q6ZLZ9", "PF3D7_0903700", "Q8ILW9", "PF3D7_1246200", "Q8I4X0", "PF3D7_1246200", "P62203", "PF14_0323", "Q8ILW9", "PF3D7_1246200", "Q8I4X0", "PF3D7_1246200", "C6KSX9", "PF3D7_0935200", "Q8I2G8", "PF3D7_0935200", "P62203", "PF14_0323", "Q8IFP3", "PF3D7_0903700", "Q6ZLZ9", "PF3D7_0903700" ] }, "reaction_10692329": { "compartment": "compartment_876", "id": "reaction_10692329", "reactome": "R-PFA-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692325" ], "products": [ "species_10692327" ], "modifiers": [], "additional_components": [ "PF3D7_1367500", "PF3D7_1367500" ] }, "reaction_10688412": { "compartment": "compartment_70101", "id": "reaction_10688412", "reactome": "R-PFA-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500430" ], "products": [ "species_83962", "species_500244" ], "modifiers": [ [ "species_10688407", "catalyst" ] ], "additional_components": [ "CHEBI:16450", "CHEBI:16704", "CHEBI:28542", "species_112016", "Q8I3X4", "PF3D7_0513300" ] }, "reaction_10703354": { "compartment": "compartment_70101", "id": "reaction_10703354", "reactome": "R-PFA-9018895", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023653", "species_29450" ], "products": [ "species_29356", "species_9023651", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10703352": { "compartment": "compartment_70101", "id": "reaction_10703352", "reactome": "R-PFA-9018868", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9020583", "species_29450" ], "products": [ "species_29356", "species_9020474", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10692893": { "compartment": "compartment_70101", "id": "reaction_10692893", "reactome": "R-PFA-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692886" ], "products": [ "species_10692888", "species_10686740" ], "modifiers": [ [ "species_10692890", "catalyst" ] ], "additional_components": [ "PF3D7_1439100", "PF3D7_1439100", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PFC1020c" ] }, "reaction_10691191": { "compartment": "compartment_876", "id": "reaction_10691191", "reactome": "R-PFA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691189" ], "products": [ "species_10691189" ], "modifiers": [ [ "species_10689280", "catalyst" ] ], "additional_components": [ "Q8IKI3", "PF3D7_1465500", "Q8I5E6", "PF3D7_1465500", "Q8IKI3", "PF3D7_1465500", "Q8I5E6", "PF3D7_1465500", "C0H4P1", "PF3D7_0934800", "Q7K6A0", "PF3D7_0934800", "Q8I719", "PF3D7_1436600" ] }, "reaction_10692412": { "compartment": "compartment_876", "id": "reaction_10692412", "reactome": "R-PFA-499981", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10692409", "catalyst" ] ], "additional_components": [ "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10687135": { "compartment": "compartment_70101", "id": "reaction_10687135", "reactome": "R-PFA-70342", "name": "ALDOB tetramer cleaves Fru-1-P to GA and DHAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31221" ], "products": [ "species_30393", "species_75970" ], "modifiers": [ [ "species_10687132", "catalyst" ] ], "additional_components": [ "Q7KQL9", "PF14_0425" ] }, "reaction_10702809": { "compartment": "compartment_70101", "id": "reaction_10702809", "reactome": "R-PFA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10702806", "catalyst" ] ], "additional_components": [ "PF3D7_0309300" ] }, "reaction_10687203": { "compartment": "compartment_70101", "id": "reaction_10687203", "reactome": "R-PFA-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10687198", "catalyst" ] ], "additional_components": [ "Q8ILA4", "PF3D7_1436000" ] }, "reaction_10687522": { "compartment": "compartment_5460", "id": "reaction_10687522", "reactome": "R-PFA-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_29362", "species_113587" ], "products": [ "species_113544", "species_113526" ], "modifiers": [ [ "species_10687371", "catalyst" ] ], "additional_components": [ "Q76NM3", "PF3D7_1324900" ] }, "reaction_10687239": { "compartment": "compartment_70101", "id": "reaction_10687239", "reactome": "R-PFA-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29492" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10687236", "catalyst" ] ], "additional_components": [ "Q8IJN7", "PF10_0155", "species_29926" ] }, "reaction_10687223": { "compartment": "compartment_70101", "id": "reaction_10687223", "reactome": "R-PFA-70486", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29728" ], "products": [ "species_29370", "species_29800" ], "modifiers": [ [ "species_10687220", "catalyst" ] ], "additional_components": [ "species_29926", "P27362", "PFI1105w" ] }, "reaction_10687207": { "compartment": "compartment_70101", "id": "reaction_10687207", "reactome": "R-PFA-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29800", "species_73473" ], "products": [ "species_29372", "species_29578", "species_29360" ], "modifiers": [ [ "species_10687178", "catalyst" ] ], "additional_components": [ "Q8IKK7", "PF3D7_1462800" ] }, "reaction_10687447": { "compartment": "compartment_70101", "id": "reaction_10687447", "reactome": "R-PFA-71495", "name": "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578", "species_75970" ], "products": [ "species_30014" ], "modifiers": [ [ "species_10687132", "catalyst" ] ], "additional_components": [ "Q7KQL9", "PF14_0425" ] }, "reaction_10687205": { "compartment": "compartment_70101", "id": "reaction_10687205", "reactome": "R-PFA-70481", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578" ], "products": [ "species_75970" ], "modifiers": [ [ "species_10687188", "catalyst" ] ], "additional_components": [ "Q7KQM0", "PF14_0378" ] }, "reaction_10687444": { "compartment": "compartment_70101", "id": "reaction_10687444", "reactome": "R-PFA-71445", "name": "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30485" ], "products": [ "species_29728" ], "modifiers": [ [ "species_10687441", "catalyst" ] ], "additional_components": [ "Q8IIG6", "PF3D7_1120100" ] }, "reaction_10687272": { "compartment": "compartment_5460", "id": "reaction_10687272", "reactome": "R-PFA-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_113552" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10689720": { "compartment": "compartment_13231", "id": "reaction_10689720", "reactome": "R-PFA-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689718" ], "products": [ "species_10687154" ], "modifiers": [], "additional_components": [ "PF3D7_0624000", "PF3D7_0624000" ] }, "reaction_10687163": { "compartment": "compartment_70101", "id": "reaction_10687163", "reactome": "R-PFA-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10687160", "catalyst" ] ], "additional_components": [ "C6KT76", "PF3D7_0624000" ] }, "reaction_10687480": { "compartment": "compartment_70101", "id": "reaction_10687480", "reactome": "R-PFA-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10687477", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_29358", "inhibitor" ], [ "species_30389", "inhibitor" ] ], "additional_components": [ "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "species_29926", "species_74126" ] }, "reaction_10703214": { "compartment": "compartment_70101", "id": "reaction_10703214", "reactome": "R-PFA-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29800" ], "products": [ "species_70106", "species_8955759", "species_29728" ], "modifiers": [ [ "species_10687120", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10699884": { "compartment": "compartment_70101", "id": "reaction_10699884", "reactome": "R-PFA-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10699881", "catalyst" ] ], "additional_components": [ "Q8IIG6", "PF3D7_1120100" ] }, "reaction_10688330": { "compartment": "compartment_70101", "id": "reaction_10688330", "reactome": "R-PFA-73646", "name": "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688318", "species_70106", "species_29364" ], "products": [ "species_29366", "species_10688320" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "P61076", "PFI1170c", "species_29386" ] }, "reaction_10687149": { "compartment": "compartment_70101", "id": "reaction_10687149", "reactome": "R-PFA-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29366" ], "products": [ "species_70106", "species_31467", "species_29364" ], "modifiers": [ [ "species_10687146", "catalyst" ] ], "additional_components": [ "species_29366", "Q8IKU0", "PF14_0511" ] }, "reaction_10703102": { "compartment": "compartment_876", "id": "reaction_10703102", "reactome": "R-PFA-8943987", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703094" ], "products": [ "species_10703100" ], "modifiers": [], "additional_components": [ "C0H518", "PF3D7_1208200", "A0A5K1K8N7", "PF3D7_1208200", "C0H518", "PF3D7_1208200", "A0A5K1K8N7", "PF3D7_1208200" ] }, "reaction_10698562": { "compartment": "compartment_12045", "id": "reaction_10698562", "reactome": "R-PFA-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690729", "species_10690727", "species_10690721" ], "products": [ "species_10690731" ], "modifiers": [], "additional_components": [ "PF3D7_0822600", "C0H489", "PF3D7_0405100", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IE08", "PF3D7_1332000", "C0H489", "PF3D7_0405100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10698618": { "compartment": "compartment_12045", "id": "reaction_10698618", "reactome": "R-PFA-5694428", "name": "LMAN family proteins bind glycosylated cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690760", "species_10690746" ], "products": [ "species_10690762" ], "modifiers": [], "additional_components": [ "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700", "Q8I2A1", "PF3D7_0103900", "Q8I2A1", "PF3D7_0103900", "O96166", "PF3D7_0207900", "Q8I1Y2", "PF3D7_0404700" ] }, "reaction_10698568": { "compartment": "compartment_12045", "id": "reaction_10698568", "reactome": "R-PFA-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690729", "species_10690665", "species_10698564" ], "products": [ "species_10698566" ], "modifiers": [], "additional_components": [ "PF3D7_0822600", "PF3D7_0320100", "C0H5J6", "PF3D7_1361100", "C0H5J6", "PF3D7_1361100", "O97323", "PF3D7_0320100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10694553": { "compartment": "compartment_70101", "id": "reaction_10694553", "reactome": "R-PFA-2161961", "name": "EET(1) is hydrolysed to DHET(1) by EPHX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2161818" ], "products": [ "species_2161883" ], "modifiers": [ [ "species_10694550", "catalyst" ] ], "additional_components": [ "CHEBI:34450", "CHEBI:34130", "CHEBI:34490", "CHEBI:34157", "CHEBI:63974", "CHEBI:63969", "CHEBI:63970", "CHEBI:63966", "species_29926", "Q8IM75", "PF3D7_1401300" ] }, "reaction_10703339": { "compartment": "compartment_5460", "id": "reaction_10703339", "reactome": "R-PFA-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703402": { "compartment": "compartment_5460", "id": "reaction_10703402", "reactome": "R-PFA-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_10703333" ], "products": [ "species_10703400", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400", "PF3D7_1206400", "PF3D7_1206400" ] }, "reaction_10703336": { "compartment": "compartment_5460", "id": "reaction_10703336", "reactome": "R-PFA-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703343": { "compartment": "compartment_5460", "id": "reaction_10703343", "reactome": "R-PFA-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703341": { "compartment": "compartment_5460", "id": "reaction_10703341", "reactome": "R-PFA-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10703333", "catalyst" ] ], "additional_components": [ "PF3D7_1206400" ] }, "reaction_10703132": { "compartment": "compartment_70101", "id": "reaction_10703132", "reactome": "R-PFA-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698288" ], "products": [ "species_10698286", "species_10698177" ], "modifiers": [], "additional_components": [ "Q8IKM8", "PF3D7_1460400", "Q8IEI4", "PF3D7_1313000", "PF3D7_1313000", "PF3D7_1460400" ] }, "reaction_10692793": { "compartment": "compartment_70101", "id": "reaction_10692793", "reactome": "R-PFA-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692761", "species_10692789" ], "products": [ "species_10692791" ], "modifiers": [], "additional_components": [ "PF3D7_1005500", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IIC9", "PF3D7_1123400", "species_29420", "O96203", "PF3D7_0212300", "Q8I5H4", "PF3D7_1224300", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "Q8IIS9", "PF3D7_1107300", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IIC9", "PF3D7_1123400", "species_29420", "O96203", "PF3D7_0212300", "A0A143ZY29", "PF3D7_1005500" ] }, "reaction_10690540": { "compartment": "compartment_70101", "id": "reaction_10690540", "reactome": "R-PFA-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10690537", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10692468": { "compartment": "compartment_70101", "id": "reaction_10692468", "reactome": "R-PFA-514604", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113578", "species_29364" ], "products": [ "species_29366", "species_29602", "species_31633" ], "modifiers": [ [ "species_10692465", "catalyst" ] ], "additional_components": [ "Q8I2U5", "PF3D7_0920800" ] }, "reaction_10688719": { "compartment": "compartment_70101", "id": "reaction_10688719", "reactome": "R-PFA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10688716", "catalyst" ] ], "additional_components": [ "Q8IE53", "PF3D7_1329400" ] }, "reaction_10688380": { "compartment": "compartment_70101", "id": "reaction_10688380", "reactome": "R-PFA-74215", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_500259" ], "products": [ "species_111294", "species_500260" ], "modifiers": [ [ "species_10688377", "catalyst" ] ], "additional_components": [ "CHEBI:16235", "species_29850", "species_29602", "species_113578", "Q8IJS1", "PF3D7_1012400", "species_29926" ] }, "reaction_10688396": { "compartment": "compartment_70101", "id": "reaction_10688396", "reactome": "R-PFA-74241", "name": "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH4+ (ADA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500173" ], "products": [ "species_500172", "species_31633" ], "modifiers": [ [ "species_10688393", "catalyst" ] ], "additional_components": [ "CHEBI:16335", "CHEBI:17256", "CHEBI:28997", "CHEBI:17596", "PF3D7_1029600" ] }, "reaction_10702565": { "compartment": "compartment_70101", "id": "reaction_10702565", "reactome": "R-PFA-8870457", "name": "FarC-PTP4A2 binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702559", "species_10702561" ], "products": [ "species_10702563" ], "modifiers": [], "additional_components": [ "PF3D7_1113100", "PF3D7_0602500", "C6KSM5", "PF3D7_0602500", "Q8IIN1", "PF3D7_1113100" ] }, "reaction_10702571": { "compartment": "compartment_70101", "id": "reaction_10702571", "reactome": "R-PFA-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702567", "species_10702561" ], "products": [ "species_10702569" ], "modifiers": [ [ "species_10702563", "inhibitor" ] ], "additional_components": [ "PF3D7_1442500", "PF3D7_0602500", "C6KSM5", "PF3D7_0602500", "Q8IL46", "PF3D7_1442500", "C6KSM5", "PF3D7_0602500", "Q8IIN1", "PF3D7_1113100" ] }, "reaction_10688826": { "compartment": "compartment_876", "id": "reaction_10688826", "reactome": "R-PFA-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10688822" ], "products": [ "species_10688824" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "Q8IIE7", "PF3D7_1121900", "species_179838" ] }, "reaction_10701191": { "compartment": "compartment_5460", "id": "reaction_10701191", "reactome": "R-PFA-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10701188", "catalyst" ] ], "additional_components": [ "Q8IKN4", "PF14_0570" ] }, "reaction_10690276": { "compartment": "compartment_70101", "id": "reaction_10690276", "reactome": "R-PFA-197186", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197230", "species_70106" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10690273", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "C6KTC6", "PF3D7_0629100" ] }, "reaction_10702553": { "compartment": "compartment_876", "id": "reaction_10702553", "reactome": "R-PFA-8869603", "name": "SLC22A13 transports NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8869604" ], "products": [ "species_197230" ], "modifiers": [ [ "species_10692518", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10701199": { "compartment": "compartment_5460", "id": "reaction_10701199", "reactome": "R-PFA-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6807477" ], "products": [ "species_113548", "species_113581", "species_113529", "species_113600" ], "modifiers": [ [ "species_10701196", "catalyst" ] ], "additional_components": [ "PF3D7_1143900" ] }, "reaction_10703211": { "compartment": "compartment_5460", "id": "reaction_10703211", "reactome": "R-PFA-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113526" ], "products": [ "species_113581", "species_113563", "species_113529" ], "modifiers": [ [ "species_10703208", "catalyst" ] ], "additional_components": [ "Q8I319", "PF3D7_0913300" ] }, "reaction_10690286": { "compartment": "compartment_70101", "id": "reaction_10690286", "reactome": "R-PFA-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_197256", "species_113592", "species_29472" ], "products": [ "species_111294", "species_29404", "species_76577", "species_29360" ], "modifiers": [ [ "species_10690283", "catalyst" ] ], "additional_components": [ "Q8I2P2", "PF3D7_0926700" ] }, "reaction_10690218": { "compartment": "compartment_70101", "id": "reaction_10690218", "reactome": "R-PFA-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196095", "species_70106", "species_29364" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10690215", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10703665": { "compartment": "compartment_70101", "id": "reaction_10703665", "reactome": "R-PFA-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10695751", "catalyst" ] ], "additional_components": [ "PF3D7_1455900" ] }, "reaction_10698686": { "compartment": "compartment_5460", "id": "reaction_10698686", "reactome": "R-PFA-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_5696835" ], "products": [ "species_113529", "species_5696848", "species_113600" ], "modifiers": [ [ "species_10698683", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10696894": { "compartment": "compartment_70101", "id": "reaction_10696894", "reactome": "R-PFA-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696892", "species_29438" ], "products": [ "species_29420", "species_10696890" ], "modifiers": [ [ "species_10690962", "catalyst" ] ], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q7KQL3", "PF10_0203", "species_29438", "PF3D7_1442900" ] }, "reaction_10690946": { "compartment": "compartment_70101", "id": "reaction_10690946", "reactome": "R-PFA-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10690943", "catalyst" ] ], "additional_components": [ "PF3D7_1033100" ] }, "reaction_10686402": { "compartment": "compartment_7660", "id": "reaction_10686402", "reactome": "R-PFA-68611", "name": "Orc1 associates with Orc4:Orc5:Orc3:Orc2:origin complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686398", "species_10686393" ], "products": [ "species_10686400" ], "modifiers": [], "additional_components": [ "PF3D7_1203000", "Q8IC17", "PF3D7_0705300", "O96237", "PF3D7_0215800", "A0A5K1K8V1", "PF3D7_1334100", "Q8IC17", "PF3D7_0705300", "O96237", "PF3D7_0215800", "A0A5K1K8V1", "PF3D7_1334100", "Q8I615", "PF3D7_1203000" ] }, "reaction_10686409": { "compartment": "compartment_7660", "id": "reaction_10686409", "reactome": "R-PFA-68637", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10686407" ], "modifiers": [], "additional_components": [ "PF3D7_0503200" ] }, "reaction_10692172": { "compartment": "compartment_70101", "id": "reaction_10692172", "reactome": "R-PFA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692164" ], "products": [ "species_10692170" ], "modifiers": [], "additional_components": [ "Q8IBK6", "PF3D7_0724600", "Q8IBK6", "PF3D7_0724600" ] }, "reaction_10693514": { "compartment": "compartment_70101", "id": "reaction_10693514", "reactome": "R-PFA-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693510" ], "products": [ "species_10693512" ], "modifiers": [], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "CHEBI:60627", "CHEBI:60628", "CHEBI:59092", "CHEBI:60629", "CHEBI:59087", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10694711": { "compartment": "compartment_70101", "id": "reaction_10694711", "reactome": "R-PFA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_179838" ], "products": [ "species_10688824" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "Q8IIE7", "PF3D7_1121900", "species_179838" ] }, "reaction_10693565": { "compartment": "compartment_70101", "id": "reaction_10693565", "reactome": "R-PFA-1250280", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688320", "species_1250243" ], "products": [ "species_10688318" ], "modifiers": [], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500" ] }, "reaction_10700704": { "compartment": "compartment_6799351", "id": "reaction_10700704", "reactome": "R-PFA-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700690" ], "products": [ "species_10700702" ], "modifiers": [], "additional_components": [ "Q8IDS0", "PF3D7_1341900", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8II31", "PF3D7_1133300", "Q8IJB1", "PF3D7_1133300", "O97295", "PF3D7_0322300", "C0H5C6", "PF3D7_1320500", "Q8ILE6", "PF3D7_1431900", "Q7KWJ5", "PF3D7_0919500", "Q8IL28", "PF3D7_1444300", "Q8IDL8", "PF3D7_1348100", "Q8I2V8", "PF3D7_0919500", "Q8IEK4", "PF3D7_1311400", "Q8I4T2", "PF3D7_1250200", "Q8I4U9", "PF3D7_1248500", "Q8I5L4", "PF3D7_1468600", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILE6", "PF3D7_1431900", "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500", "Q8IEK4", "PF3D7_1311400", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IL28", "PF3D7_1444300", "Q8I4U9", "PF3D7_1248500", "Q8IDL8", "PF3D7_1348100", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "O97295", "PF3D7_0322300", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10700208": { "compartment": "compartment_6799713", "id": "reaction_10700208", "reactome": "R-PFA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700192" ], "products": [ "species_10700206" ], "modifiers": [], "additional_components": [ "Q8I3R7", "PF3D7_0519200", "Q7KWJ5", "PF3D7_0919500", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILG6", "PF3D7_1429800", "Q8I3M7", "PF3D7_0523800", "Q8I5R9", "PF3D7_1357300", "Q8IBG2", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8I4T2", "PF3D7_1250200", "C0H5C6", "PF3D7_1320500", "Q8ILG6", "PF3D7_1429800", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q7KWJ5", "PF3D7_0919500", "Q8I3R7", "PF3D7_0519200", "Q8I3M7", "PF3D7_0523800" ] }, "reaction_10700629": { "compartment": "compartment_1470028", "id": "reaction_10700629", "reactome": "R-PFA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700591" ], "products": [ "species_10700627" ], "modifiers": [], "additional_components": [ "Q8IM42", "PF3D7_1405200", "O96220", "PF3D7_0214000", "Q7KQL5", "PF10_0084", "C6KT34", "PF3D7_0619400", "Q8IKH3", "PF3D7_1466300", "C6KSW6", "PF3D7_0822500", "Q8I412", "PF3D7_0822500", "Q8IB59", "PF3D7_0822500", "Q8IAM2", "PF3D7_0802200", "Q8I1V9", "PF3D7_0409900", "C6KTC6", "PF3D7_0629100", "Q8I384", "PF3D7_0906500", "Q8ID33", "PF3D7_1367500", "Q8ILI2", "PF3D7_1428300", "Q8IM55", "PF3D7_1403900", "Q8I501", "PF3D7_1242800", "O96166", "PF3D7_0207900", "O97247", "PF3D7_0306800", "Q8I2H1", "PF3D7_0934700", "Q8ID33", "PF3D7_1367500", "Q8I384", "PF3D7_0906500", "C6KSW6", "PF3D7_0822500", "Q8IB59", "PF3D7_0822500", "Q8I412", "PF3D7_0822500", "Q8ILI2", "PF3D7_1428300", "C6KTC6", "PF3D7_0629100", "Q8IM42", "PF3D7_1405200", "C6KT34", "PF3D7_0619400", "O97247", "PF3D7_0306800", "O96220", "PF3D7_0214000", "Q7KQL5", "PF10_0084", "Q8IKH3", "PF3D7_1466300", "Q8IAM2", "PF3D7_0802200", "Q8I501", "PF3D7_1242800", "Q8I1V9", "PF3D7_0409900", "O96166", "PF3D7_0207900", "Q8IM55", "PF3D7_1403900", "Q8I2H1", "PF3D7_0934700" ] }, "reaction_10700075": { "compartment": "compartment_876", "id": "reaction_10700075", "reactome": "R-PFA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700049" ], "products": [ "species_10700073" ], "modifiers": [], "additional_components": [ "C6KT12", "PF3D7_1246300", "Q7K6B0", "PF3D7_0807300", "Q76NM7", "PF3D7_1310600", "Q7KWJ5", "PF3D7_0919500", "O97278", "PF3D7_0319700", "Q8ILG6", "PF3D7_1429800", "Q8I274", "PF3D7_0211200", "C0H516", "PF3D7_0903200", "Q8IHR8", "PF3D7_1144900", "Q8IAQ8", "PF3D7_0806800", "C0H4M1", "PF3D7_0707400", "Q8I385", "PF3D7_0906400", "Q8I274", "PF3D7_0211200", "O97278", "PF3D7_0319700", "Q76NM7", "PF3D7_1310600", "C0H516", "PF3D7_0903200", "Q8IHR8", "PF3D7_1144900", "Q7KWJ5", "PF3D7_0919500", "C6KT12", "PF3D7_1246300", "C0H4M1", "PF3D7_0707400", "Q8ILG6", "PF3D7_1429800", "Q8I385", "PF3D7_0906400", "Q8IAQ8", "PF3D7_0806800", "Q7K6B0", "PF3D7_0807300" ] }, "reaction_10700489": { "compartment": "compartment_1462052", "id": "reaction_10700489", "reactome": "R-PFA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700371" ], "products": [ "species_10700487" ], "modifiers": [], "additional_components": [ "Q8IL68", "PF3D7_1440300", "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "Q8IE53", "PF3D7_1329400", "C0H568", "PF3D7_0927500", "Q8IBH5", "PF3D7_1110700", "A0A143ZXR3", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8I0P6", "PF3D7_1357000", "Q8IB94", "PF3D7_0826100", "Q7KQL9", "PF14_0425", "Q8IIA3", "PF3D7_1126100", "Q8IKW5", "PF3D7_1451100", "Q8IAU1", "PF3D7_0810600", "Q8ILA4", "PF3D7_1436000", "Q8I323", "PF3D7_0912900", "Q8IJS0", "PF3D7_1012500", "Q8IDR5", "PF3D7_1342400", "Q8IC05", "PF3D7_1443900", "A0A5K1K9F3", "PF3D7_1338100", "Q8IB24", "PF3D7_0818900", "Q8II71", "PF3D7_1129200", "Q8ID28", "PF3D7_1368100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "O96153", "PF3D7_0205900", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IJM0", "PF3D7_1017900", "Q8IJA0", "PF3D7_1030500", "Q8I616", "PF3D7_1202900", "Q8IEK3", "PF3D7_1311500", "C6KT76", "PF3D7_0624000", "Q8IM66", "PF3D7_1402300", "C6KST3", "PF3D7_0608500", "Q8I613", "PF3D7_1203200", "Q8I6T3", "PF3D7_1328100", "Q8II60", "PF3D7_1130400", "A0A5K1K7U1", "PF3D7_0518300", "C6KT01", "PF3D7_0616000", "Q8IBI3", "PF3D7_0727400", "C6KT34", "PF3D7_0619400", "O96220", "PF3D7_0214000", "Q8IIG6", "PF3D7_1120100", "Q8ID43", "PF3D7_1366500", "Q8I5C5", "PF3D7_1229400", "Q8I5Q4", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q76NN7", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "Q8I501", "PF3D7_1242800", "Q8IM66", "PF3D7_1402300", "Q8I0P6", "PF3D7_1357000", "Q8IJM0", "PF3D7_1017900", "Q8IB94", "PF3D7_0826100", "Q8I5C5", "PF3D7_1229400", "Q8II60", "PF3D7_1130400", "Q8IJS0", "PF3D7_1012500", "Q8IEK3", "PF3D7_1311500", "Q8IKW5", "PF3D7_1451100", "C6KT34", "PF3D7_0619400", "Q8IB24", "PF3D7_0818900", "Q8I613", "PF3D7_1203200", "Q8ILA4", "PF3D7_1436000", "O96220", "PF3D7_0214000", "C6KT01", "PF3D7_0616000", "Q8IC05", "PF3D7_1443900", "Q8I501", "PF3D7_1242800", "C6KT76", "PF3D7_0624000", "Q8IL32", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "Q8IE53", "PF3D7_1329400", "Q8I6T3", "PF3D7_1328100", "A0A143ZXR3", "PF3D7_1110700", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8I616", "PF3D7_1202900", "Q8IIA3", "PF3D7_1126100", "Q8IBI3", "PF3D7_0727400", "Q8IAU1", "PF3D7_0810600", "C6KST3", "PF3D7_0608500", "Q8ID43", "PF3D7_1366500", "Q8IDR5", "PF3D7_1342400", "A0A5K1K7U1", "PF3D7_0518300", "Q8IIG6", "PF3D7_1120100", "Q76NN7", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "Q7KQL9", "PF14_0425", "Q8II71", "PF3D7_1129200", "Q8I323", "PF3D7_0912900", "O96153", "PF3D7_0205900", "C6KTA4", "PF3D7_1037100", "Q8IJ37", "PF3D7_1037100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "A0A5K1K9F3", "PF3D7_1338100", "Q8IJA0", "PF3D7_1030500", "C0H568", "PF3D7_0927500", "Q8ID28", "PF3D7_1368100", "Q8IL68", "PF3D7_1440300" ] }, "reaction_10700520": { "compartment": "compartment_6799371", "id": "reaction_10700520", "reactome": "R-PFA-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700508" ], "products": [ "species_10700518" ], "modifiers": [], "additional_components": [ "C6KT01", "PF3D7_0616000", "Q8IAY9", "PF3D7_0815200", "Q8I384", "PF3D7_0906500", "Q8I509", "PF3D7_1242000", "Q8I1Y2", "PF3D7_0404700", "Q8I6Z5", "PF3D7_1323500", "Q8I486", "PF3D7_0501400", "Q8I384", "PF3D7_0906500", "Q8I486", "PF3D7_0501400", "Q8I6Z5", "PF3D7_1323500", "Q8I509", "PF3D7_1242000", "Q8I1Y2", "PF3D7_0404700", "Q8IAY9", "PF3D7_0815200", "C6KT01", "PF3D7_0616000" ] }, "reaction_10700136": { "compartment": "compartment_6800173", "id": "reaction_10700136", "reactome": "R-PFA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700108" ], "products": [ "species_10700134" ], "modifiers": [], "additional_components": [ "Q8I509", "PF3D7_1242000", "Q8I2Q2", "PF3D7_0925600", "Q8I6Z5", "PF3D7_1323500", "Q7KQL9", "PF14_0425", "Q8I6U4", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q7KQL9", "PF14_0425", "Q8I6Z5", "PF3D7_1323500", "Q8I509", "PF3D7_1242000", "Q8IIL0", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8I2Q2", "PF3D7_0925600" ] }, "reaction_10700943": { "compartment": "compartment_984", "id": "reaction_10700943", "reactome": "R-PFA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700933" ], "products": [ "species_10700941" ], "modifiers": [], "additional_components": [ "Q8IKW5", "PF3D7_1451100", "C0H568", "PF3D7_0927500", "Q8IB94", "PF3D7_0826100", "Q8IJ37", "PF3D7_1037100", "C6KTA4", "PF3D7_1037100", "Q8IL68", "PF3D7_1440300", "Q76NN7", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q8IIK8", "PF3D7_1215200", "A0A5K1K7U1", "PF3D7_0518300", "Q8ID28", "PF3D7_1368100", "Q8ID43", "PF3D7_1366500", "O96153", "PF3D7_0205900", "C6KST3", "PF3D7_0608500", "Q8IJM0", "PF3D7_1017900", "Q8IBI3", "PF3D7_0727400", "Q8IJA0", "PF3D7_1030500", "Q8I616", "PF3D7_1202900", "Q8IEK3", "PF3D7_1311500", "Q8I6T3", "PF3D7_1328100", "Q8IM66", "PF3D7_1402300", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "Q8I613", "PF3D7_1203200", "C6KT76", "PF3D7_0624000", "Q8II60", "PF3D7_1130400", "C6KT34", "PF3D7_0619400", "Q8ILA4", "PF3D7_1436000", "Q8IB24", "PF3D7_0818900", "Q7KQL9", "PF14_0425", "Q8IJS0", "PF3D7_1012500", "Q8IIA3", "PF3D7_1126100", "P62203", "PF14_0323", "Q8IE53", "PF3D7_1329400", "Q8IAU1", "PF3D7_0810600", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "A0A143ZXR3", "PF3D7_1110700", "O97289", "PF3D7_0321500", "Q8I1V9", "PF3D7_0409900", "Q8IAY9", "PF3D7_0815200", "O96220", "PF3D7_0214000", "Q8I323", "PF3D7_0912900", "Q8I2Q2", "PF3D7_0925600", "Q8IIG6", "PF3D7_1120100", "A0A5K1K9F3", "PF3D7_1338100", "Q8I5C5", "PF3D7_1229400", "Q8II71", "PF3D7_1129200", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "Q8I1Y2", "PF3D7_0404700", "Q8I6Z5", "PF3D7_1323500", "Q8IDR5", "PF3D7_1342400", "Q8IIJ9", "PF11_0174", "Q8I0P6", "PF3D7_1357000", "Q8IAY9", "PF3D7_0815200", "Q8IJA0", "PF3D7_1030500", "A0A5K1K9F3", "PF3D7_1338100", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800", "Q8IIL0", "PF3D7_1247800", "O96153", "PF3D7_0205900", "Q8I323", "PF3D7_0912900", "Q8II71", "PF3D7_1129200", "Q8I6Z5", "PF3D7_1323500", "Q8I1V9", "PF3D7_0409900", "Q7KQL9", "PF14_0425", "Q8I2Q2", "PF3D7_0925600", "Q8IIG6", "PF3D7_1120100", "A0A5K1K7U1", "PF3D7_0518300", "Q8ID43", "PF3D7_1366500", "Q8IAU1", "PF3D7_0810600", "Q8IIA3", "PF3D7_1126100", "A0A143ZXR3", "PF3D7_1110700", "Q8IBH5", "PF3D7_1110700", "Q8I2A2", "PF3D7_1110700", "Q8IE53", "PF3D7_1329400", "O96220", "PF3D7_0214000", "Q8I613", "PF3D7_1203200", "C6KT34", "PF3D7_0619400", "Q8I1Y2", "PF3D7_0404700", "Q8IEK3", "PF3D7_1311500", "Q8II60", "PF3D7_1130400", "Q8I5C5", "PF3D7_1229400", "Q8IJM0", "PF3D7_1017900", "Q8IM66", "PF3D7_1402300", "Q8IL68", "PF3D7_1440300", "C0H568", "PF3D7_0927500", "C6KTA4", "PF3D7_1037100", "Q8IJ37", "PF3D7_1037100", "Q8IIK8", "PF3D7_1215200", "Q8I621", "PF3D7_1215200", "Q8I5Q4", "PF3D7_1215200", "Q76NN7", "PF3D7_1215200", "P62203", "PF14_0323", "Q8IIJ9", "PF11_0174", "O97289", "PF3D7_0321500", "Q8IDR5", "PF3D7_1342400", "C6KST3", "PF3D7_0608500", "Q8IBI3", "PF3D7_0727400", "Q8I616", "PF3D7_1202900", "Q8I6T3", "PF3D7_1328100", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "C6KT76", "PF3D7_0624000", "Q8ILA4", "PF3D7_1436000", "Q8IB24", "PF3D7_0818900", "Q8IKW5", "PF3D7_1451100", "Q8IJS0", "PF3D7_1012500", "Q8IB94", "PF3D7_0826100", "Q8I0P6", "PF3D7_1357000", "Q8ID28", "PF3D7_1368100" ] }, "reaction_10699997": { "compartment": "compartment_6798757", "id": "reaction_10699997", "reactome": "R-PFA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699963" ], "products": [ "species_10699995" ], "modifiers": [], "additional_components": [ "Q8I3R7", "PF3D7_0519200", "Q8IL71", "PF3D7_1439800", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I5L4", "PF3D7_1468600", "O77368", "PF3D7_1468600", "O97278", "PF3D7_0319700", "Q8I2V7", "PF3D7_0919600", "B9ZSI6", "PF3D7_0107700", "O96171", "PF3D7_0208400", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IDL8", "PF3D7_1348100", "Q8I310", "PF3D7_0914200", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "C0H5C6", "PF3D7_1320500", "Q8I3F8", "PF3D7_0531000", "O96171", "PF3D7_0208400", "Q8I5L4", "PF3D7_1468600", "O97278", "PF3D7_0319700", "Q8I3F8", "PF3D7_0531000", "O77368", "PF3D7_1468600", "Q8IKF1", "PF3D7_1468600", "Q8IHY1", "PF3D7_1468600", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "Q8I3R7", "PF3D7_0519200", "C0H5C6", "PF3D7_1320500", "Q8IL71", "PF3D7_1439800", "Q8IJB1", "PF3D7_1133300", "Q8II31", "PF3D7_1133300", "Q8IDL8", "PF3D7_1348100", "Q8I2V7", "PF3D7_0919600", "B9ZSI6", "PF3D7_0107700", "Q8I310", "PF3D7_0914200" ] }, "reaction_10700781": { "compartment": "compartment_6800424", "id": "reaction_10700781", "reactome": "R-PFA-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700769" ], "products": [ "species_10700779" ], "modifiers": [], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I385", "PF3D7_0906400", "C6KT12", "PF3D7_1246300", "Q8IIL9", "PF3D7_1114200", "Q8I379", "PF3D7_1114200", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8ILG6", "PF3D7_1429800", "Q8I3M7", "PF3D7_0523800", "C0H4M1", "PF3D7_0707400", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "C6KT12", "PF3D7_1246300", "C0H4M1", "PF3D7_0707400", "Q8I379", "PF3D7_1114200", "Q8IIL9", "PF3D7_1114200", "Q8ILG6", "PF3D7_1429800", "Q8I385", "PF3D7_0906400", "Q8IBG2", "PF3D7_1357300", "Q8I5R9", "PF3D7_1357300", "Q8IDD2", "PF3D7_1357300", "Q8IAQ8", "PF3D7_0806800", "Q7KWJ5", "PF3D7_0919500", "Q8I3R7", "PF3D7_0519200", "Q8I3M7", "PF3D7_0523800" ] }, "reaction_10701410": { "compartment": "compartment_984", "id": "reaction_10701410", "reactome": "R-PFA-6810724", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803081", "species_10701406" ], "products": [ "species_10701408" ], "modifiers": [], "additional_components": [ "Q8I486", "PF3D7_0501400", "Q8I486", "PF3D7_0501400", "species_166005" ] }, "reaction_10701031": { "compartment": "compartment_984", "id": "reaction_10701031", "reactome": "R-PFA-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_181015", "species_10701027" ], "products": [ "species_10701029" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "Q8I616", "PF3D7_1202900", "species_181015" ] }, "reaction_10701035": { "compartment": "compartment_984", "id": "reaction_10701035", "reactome": "R-PFA-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10701027" ], "products": [ "species_10701033" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "Q8I616", "PF3D7_1202900", "species_166005" ] }, "reaction_10701162": { "compartment": "compartment_984", "id": "reaction_10701162", "reactome": "R-PFA-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690933" ], "products": [ "species_10701027" ], "modifiers": [], "additional_components": [ "PF3D7_1202900", "PF3D7_1202900" ] }, "reaction_10703347": { "compartment": "compartment_70101", "id": "reaction_10703347", "reactome": "R-PFA-9013869", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694974", "species_8982080" ], "products": [ "species_10703345" ], "modifiers": [], "additional_components": [ "PF3D7_0527900", "CHEBI:49537", "CHEBI:47037", "CHEBI:49537", "CHEBI:47037", "A0A5K1K8X8", "PF3D7_0527900" ] }, "reaction_10694983": { "compartment": "compartment_70101", "id": "reaction_10694983", "reactome": "R-PFA-3134962", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3134861", "species_10694979" ], "products": [ "species_10694981" ], "modifiers": [], "additional_components": [ "PF3D7_0310500", "O77360", "PF3D7_0310500" ] }, "reaction_10690562": { "compartment": "compartment_70101", "id": "reaction_10690562", "reactome": "R-PFA-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_202277" ], "products": [ "species_10690560" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "species_202247", "species_179838", "Q8IIE7", "PF3D7_1121900", "species_202247", "species_179838" ] }, "reaction_10693549": { "compartment": "compartment_1222693", "id": "reaction_10693549", "reactome": "R-PFA-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10693546", "catalyst" ] ], "additional_components": [ "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900", "Q8IKJ0", "PF3D7_1464700", "Q8IDF7", "PF3D7_1354400", "C0H4P0", "PF3D7_0721900", "Q8IAQ8", "PF3D7_0806800", "Q8I3R7", "PF3D7_0519200" ] }, "reaction_10688366": { "compartment": "compartment_70101", "id": "reaction_10688366", "reactome": "R-PFA-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_111584", "species_29472" ], "products": [ "species_111294", "species_29404", "species_113578", "species_76577" ], "modifiers": [ [ "species_10688363", "catalyst" ] ], "additional_components": [ "PF3D7_1012600" ] }, "reaction_10689181": { "compartment": "compartment_70101", "id": "reaction_10689181", "reactome": "R-PFA-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29448", "species_29602" ], "products": [ "species_29372", "species_29420", "species_35141" ], "modifiers": [ [ "species_10689178", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_30014", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_113578", "inhibitor" ] ], "additional_components": [ "species_29926", "Q8IDF6", "PF13_0287" ] }, "reaction_10698331": { "compartment": "compartment_7660", "id": "reaction_10698331", "reactome": "R-PFA-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698328", "species_30555" ], "products": [ "species_10698326", "species_113541" ], "modifiers": [ [ "species_10698328", "catalyst" ] ], "additional_components": [ "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10690535": { "compartment": "compartment_70101", "id": "reaction_10690535", "reactome": "R-PFA-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10690512" ], "products": [ "species_29370", "species_10690533" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "Q8IC05", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8I0V4", "PF3D7_1443900", "P62203", "PF14_0323", "species_74016", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10693927": { "compartment": "compartment_70101", "id": "reaction_10693927", "reactome": "R-PFA-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10690533" ], "products": [ "species_10690537" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10689795": { "compartment": "compartment_70101", "id": "reaction_10689795", "reactome": "R-PFA-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_174390" ], "products": [ "species_111294", "species_29372", "species_71284" ], "modifiers": [ [ "species_10689792", "catalyst" ] ], "additional_components": [ "species_29926", "Q7K6A4", "PF3D7_0922200", "species_74126" ] }, "reaction_10689813": { "compartment": "compartment_70101", "id": "reaction_10689813", "reactome": "R-PFA-175983", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175977", "species_71284" ], "products": [ "species_175978", "species_71285" ], "modifiers": [ [ "species_10689810", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10700735": { "compartment": "compartment_70101", "id": "reaction_10700735", "reactome": "R-PFA-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10700729", "catalyst" ] ], "additional_components": [ "Q8IET4", "PF3D7_1303100", "Q8IM19", "PF3D7_1407500" ] }, "reaction_10698363": { "compartment": "compartment_70101", "id": "reaction_10698363", "reactome": "R-PFA-5692232", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_5692212" ], "products": [ "species_5692216", "species_29364" ], "modifiers": [ [ "species_10697185", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10689805": { "compartment": "compartment_70101", "id": "reaction_10689805", "reactome": "R-PFA-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174393", "species_113592", "species_29424" ], "products": [ "species_29372", "species_29370", "species_29450" ], "modifiers": [ [ "species_10689802", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "species_29926", "Q8I3Y4", "PF3D7_0512200" ] }, "reaction_10689823": { "compartment": "compartment_70101", "id": "reaction_10689823", "reactome": "R-PFA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_176070" ], "products": [ "species_176049" ], "modifiers": [ [ "species_10689820", "catalyst" ] ], "additional_components": [ "CHEBI:29132", "CHEBI:34718", "CHEBI:30614", "CHEBI:8927", "CHEBI:32639", "CHEBI:34479", "Q8ILQ7", "PF14_0187" ] }, "reaction_10687505": { "compartment": "compartment_70101", "id": "reaction_10687505", "reactome": "R-PFA-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29416", "species_76194" ], "products": [ "species_111294", "species_76183", "species_76577" ], "modifiers": [ [ "species_10687502", "catalyst" ] ], "additional_components": [ "PF3D7_0627800" ] }, "reaction_10692132": { "compartment": "compartment_5460", "id": "reaction_10692132", "reactome": "R-PFA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_113539" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10692129", "catalyst" ] ], "additional_components": [ "PF3D7_0627800" ] }, "reaction_10689254": { "compartment": "compartment_7660", "id": "reaction_10689254", "reactome": "R-PFA-111915", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10689245" ], "products": [ "species_113582", "species_10689251" ], "modifiers": [ [ "species_10689245", "catalyst" ] ], "additional_components": [ "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323", "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323", "Q8IIV3", "PF3D7_1104900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10691885": { "compartment": "compartment_70101", "id": "reaction_10691885", "reactome": "R-PFA-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10691877" ], "products": [ "species_113582", "species_10691882" ], "modifiers": [ [ "species_10691877", "catalyst" ] ], "additional_components": [ "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10699811": { "compartment": "compartment_70101", "id": "reaction_10699811", "reactome": "R-PFA-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699781", "species_10699783" ], "products": [ "species_10699789", "species_10699791", "species_10699785", "species_10699803", "species_10699787", "species_10699797", "species_10687798", "species_10699783", "species_10699793", "species_10691650", "species_10699795" ], "modifiers": [ [ "species_10699789", "catalyst" ], [ "species_10699809", "catalyst" ], [ "species_10699803", "catalyst" ], [ "species_10691650", "catalyst" ] ], "additional_components": [ "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IM10", "PF3D7_1408600", "Q8IDR9", "PF3D7_1342000", "Q8IKL9", "PF3D7_1461300", "O97313", "PFC1020c", "Q8I1N8", "PF3D7_0420100", "Q8IAX5", "PF3D7_0813900", "Q8IKE4", "PF3D7_1469300", "O97248", "PF3D7_0306900", "Q8IDB0", "PF3D7_1358800", "Q8I1Q0", "PF3D7_0418700", "O77395", "PF3D7_0316800", "O96224", "PF3D7_0214400", "O77381", "PF3D7_0317600", "C6KT53", "PF3D7_0621500", "Q8IDN4", "PF3D7_1346300", "Q8IAX8", "PF3D7_1346300", "Q8IIR2", "PF3D7_1109400", "Q8IIU8", "PF3D7_1105400", "Q8IEN2", "PF3D7_1308300", "Q8I3R6", "PF3D7_0519400", "Q8IE34", "PF3D7_1327200", "Q8IKH8", "PF3D7_1465900", "Q8IJD4", "PF10_0264", "Q7KQK2", "PF3D7_1402500", "C0H4K8", "PF3D7_0705700", "Q8ILN8", "PF3D7_1421200", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2", "O96258", "PF3D7_0217800", "Q8IK02", "PF3D7_1003500", "Q8IHS5", "PF3D7_1144000", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "C0H5C2", "PF3D7_1317800", "A0A5K1K925", "PF3D7_0516200", "A0A144A2N6", "PF3D7_1230900", "Q8I502", "PF3D7_1242700", "Q8IKV7", "PF3D7_1451900", "Q8IBQ5", "PF3D7_0719700", "Q8IET7", "PF3D7_1302800", "O97249", "PF3D7_0307100", "Q8I3R0", "PF3D7_0520000", "PF3D7_1230900", "PF3D7_0418700", "PF3D7_1469300", "PF3D7_1109400", "C6S3F7", "PF3D7_1136500.2", "Q8IHZ9", "PF3D7_1136500.1", "PF3D7_0214400", "PF3D7_1230900", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "PF3D7_1230900", "PF3D7_0420100", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2", "PF3D7_1451900", "PF3D7_0418700", "PF3D7_0522300", "C6S3F7", "PF3D7_1136500.2", "Q8IHZ9", "PF3D7_1136500.1", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2" ] }, "reaction_10697067": { "compartment": "compartment_17963", "id": "reaction_10697067", "reactome": "R-PFA-5653873", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_964746" ], "modifiers": [ [ "species_10697064", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10694064": { "compartment": "compartment_171062", "id": "reaction_10694064", "reactome": "R-PFA-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10701695": { "compartment": "compartment_70101", "id": "reaction_10701695", "reactome": "R-PFA-8849969", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8849959" ], "products": [ "species_29372", "species_8849958" ], "modifiers": [ [ "species_10701692", "catalyst" ] ], "additional_components": [ "species_179838", "species_202247", "species_179856", "species_1806200", "species_1806224", "species_1806240", "PF3D7_1354200" ] }, "reaction_10694096": { "compartment": "compartment_876", "id": "reaction_10694096", "reactome": "R-PFA-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10693987", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694013": { "compartment": "compartment_876", "id": "reaction_10694013", "reactome": "R-PFA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806240", "species_113592" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10694010", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10688787": { "compartment": "compartment_7660", "id": "reaction_10688787", "reactome": "R-PFA-77584", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688783", "species_10688778" ], "products": [ "species_10688785" ], "modifiers": [], "additional_components": [ "PF3D7_0927600", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I2N3", "PF3D7_0927600" ] }, "reaction_10689594": { "compartment": "compartment_876", "id": "reaction_10689594", "reactome": "R-PFA-165026", "name": "OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164988", "species_74113" ], "products": [ "species_30235", "species_83910" ], "modifiers": [ [ "species_10689591", "catalyst" ] ], "additional_components": [ "PF3D7_1203400" ] }, "reaction_10688242": { "compartment": "compartment_70101", "id": "reaction_10688242", "reactome": "R-PFA-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687916", "species_10687864", "species_10687881", "species_72617", "species_10687921" ], "products": [ "species_10687916", "species_10687864", "species_10687881", "species_72617", "species_10687921" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "PF3D7_1206700", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "PF3D7_1206700" ] }, "reaction_10687927": { "compartment": "compartment_70101", "id": "reaction_10687927", "reactome": "R-PFA-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687916", "species_113592" ], "products": [ "species_10687916", "species_29372", "species_29370" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10688234": { "compartment": "compartment_70101", "id": "reaction_10688234", "reactome": "R-PFA-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687864", "species_10688215" ], "products": [ "species_10687864", "species_10688213", "species_10687798" ], "modifiers": [], "additional_components": [ "PF3D7_1143400", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "PF3D7_1143400", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600" ] }, "reaction_10688238": { "compartment": "compartment_70101", "id": "reaction_10688238", "reactome": "R-PFA-72676", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687864", "species_10687798", "species_10687859" ], "products": [ "species_10688236" ], "modifiers": [], "additional_components": [ "PF3D7_1143400", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400" ] }, "reaction_10687937": { "compartment": "compartment_70101", "id": "reaction_10687937", "reactome": "R-PFA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687883", "species_72393" ], "products": [ "species_10687885" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10688240": { "compartment": "compartment_70101", "id": "reaction_10688240", "reactome": "R-PFA-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688236", "species_10687885" ], "products": [ "species_10687887" ], "modifiers": [], "additional_components": [ "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IAZ3", "PF3D7_0815600", "Q8I3I5", "PF3D7_0528200", "Q8I2X0", "PF3D7_0918300", "Q9NFE6", "PF3D7_0310600.1", "Q8I3T1", "PF3D7_0517700", "C6KSW5", "PF3D7_0612100", "Q8I5S6", "PF3D7_1212700", "Q8I1Q5", "PF3D7_0418200", "Q8IJW4", "PF3D7_1007900", "Q8IBT2", "PF3D7_0716800", "Q8I5Y3", "PF3D7_1206200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8IHT2", "PF3D7_1143400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10687935": { "compartment": "compartment_70101", "id": "reaction_10687935", "reactome": "R-PFA-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10687881" ], "products": [ "species_10687883" ], "modifiers": [], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438" ] }, "reaction_10687929": { "compartment": "compartment_70101", "id": "reaction_10687929", "reactome": "R-PFA-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687903", "species_10687898", "species_10687908" ], "products": [ "species_10687910" ], "modifiers": [], "additional_components": [ "PF3D7_0315100", "Q8IKF0", "PF3D7_1468700", "PF3D7_1107300", "Q8IIS9", "PF3D7_1107300", "Q8IKF0", "PF3D7_1468700", "O97266", "PF3D7_0315100" ] }, "reaction_10688230": { "compartment": "compartment_70101", "id": "reaction_10688230", "reactome": "R-PFA-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688224" ], "products": [ "species_29372", "species_10688228", "species_10688226" ], "modifiers": [], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29438", "C6KSR8", "PF3D7_0607000", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29420", "C6KSR8", "PF3D7_0607000" ] }, "reaction_10688232": { "compartment": "compartment_70101", "id": "reaction_10688232", "reactome": "R-PFA-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688222", "species_10688213", "species_10687923" ], "products": [ "species_10688224" ], "modifiers": [], "additional_components": [ "species_29438", "C6KSR8", "PF3D7_0607000", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q7KQK2", "PF3D7_1402500", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "species_29438", "C6KSR8", "PF3D7_0607000" ] }, "reaction_10687968": { "compartment": "compartment_70101", "id": "reaction_10687968", "reactome": "R-PFA-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687964", "species_10687925" ], "products": [ "species_10687966" ], "modifiers": [], "additional_components": [ "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400" ] }, "reaction_10688245": { "compartment": "compartment_70101", "id": "reaction_10688245", "reactome": "R-PFA-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10687966" ], "products": [ "species_10687964", "species_29420", "species_10687883" ], "modifiers": [ [ "species_10687964", "catalyst" ] ], "additional_components": [ "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29420", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400", "Q8IJT9", "PF3D7_1010600", "Q8ILY9", "PF3D7_1410600", "Q8IBH7", "PF3D7_0728000", "species_29438", "Q8IJQ6", "PF3D7_1013900", "Q8IBB6", "PF3D7_0828500", "A0A144A0U7", "PF3D7_1213900", "Q8I4S8", "PF3D7_1250600", "A0A5K1K977", "PF3D7_1326400" ] }, "reaction_10689620": { "compartment": "compartment_70101", "id": "reaction_10689620", "reactome": "R-PFA-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10687908" ], "products": [ "species_29370", "species_10689618" ], "modifiers": [ [ "species_10689603", "catalyst" ] ], "additional_components": [ "PF3D7_1107300", "PF3D7_1107300", "PF3D7_1246900" ] }, "reaction_10689613": { "compartment": "compartment_70101", "id": "reaction_10689613", "reactome": "R-PFA-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10687760" ], "products": [ "species_29370", "species_10689610" ], "modifiers": [ [ "species_10689603", "catalyst" ] ], "additional_components": [ "PF3D7_1342000", "PF3D7_1342000", "PF3D7_1246900" ] }, "reaction_10702534": { "compartment": "compartment_876", "id": "reaction_10702534", "reactome": "R-PFA-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10693985", "catalyst" ] ], "additional_components": [ "PF3D7_0110600" ] }, "reaction_10702417": { "compartment": "compartment_70101", "id": "reaction_10702417", "reactome": "R-PFA-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702413", "species_10702401" ], "products": [ "species_10702415" ], "modifiers": [], "additional_components": [ "O97322", "PF3D7_1025000", "Q8IJF4", "PF3D7_1025000", "Q8I4X4", "PF3D7_1245800", "Q8II45", "PF3D7_1132000", "Q8IIM8", "PF3D7_1132000", "Q8I2T2", "PF3D7_1132000", "Q8II45", "PF3D7_1132000", "Q8IIM8", "PF3D7_1132000", "Q8I2T2", "PF3D7_1132000", "O97322", "PF3D7_1025000", "Q8IJF4", "PF3D7_1025000", "Q8I4X4", "PF3D7_1245800" ] }, "reaction_10702263": { "compartment": "compartment_70101", "id": "reaction_10702263", "reactome": "R-PFA-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698282", "species_10702261" ], "products": [ "species_10702247" ], "modifiers": [], "additional_components": [ "PF3D7_1313000", "Q8IL63", "PF3D7_1440700", "Q8I5M5", "PF3D7_1440700", "Q8I5M5", "PF3D7_1440700", "Q8IL63", "PF3D7_1440700" ] }, "reaction_10703640": { "compartment": "compartment_70101", "id": "reaction_10703640", "reactome": "R-PFA-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10702203" ], "products": [ "species_10703638" ], "modifiers": [], "additional_components": [ "Q8I3I6", "PF3D7_0528100", "C6KT12", "PF3D7_1246300", "Q8I4W9", "PF3D7_1246300", "Q8I5M5", "PF3D7_1440700", "O96254", "PF3D7_0217300", "Q8I3I6", "PF3D7_0528100", "C6KT12", "PF3D7_1246300", "Q8I4W9", "PF3D7_1246300", "Q8I5M5", "PF3D7_1440700", "O96254", "PF3D7_0217300" ] }, "reaction_10694563": { "compartment": "compartment_5460", "id": "reaction_10694563", "reactome": "R-PFA-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162265", "species_2162212" ], "products": [ "species_2162252", "species_113529", "species_2162198" ], "modifiers": [ [ "species_10694560", "catalyst" ] ], "additional_components": [ "PF3D7_0724300" ] }, "reaction_10694571": { "compartment": "compartment_70616", "id": "reaction_10694571", "reactome": "R-PFA-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10694568", "catalyst" ] ], "additional_components": [ "PF3D7_0607500" ] }, "reaction_10694574": { "compartment": "compartment_5460", "id": "reaction_10694574", "reactome": "R-PFA-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162265", "species_2162209" ], "products": [ "species_2162252", "species_113529", "species_2162215" ], "modifiers": [ [ "species_10694560", "catalyst" ] ], "additional_components": [ "PF3D7_0724300" ] }, "reaction_10694588": { "compartment": "compartment_5460", "id": "reaction_10694588", "reactome": "R-PFA-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162257", "species_2162256" ], "products": [ "species_159450", "species_2162214" ], "modifiers": [ [ "species_10694585", "catalyst" ] ], "additional_components": [ "O96130", "PF3D7_0202700", "species_29926" ] }, "reaction_10688699": { "compartment": "compartment_7660", "id": "reaction_10688699", "reactome": "R-PFA-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688694", "species_30595" ], "products": [ "species_10688696", "species_113541" ], "modifiers": [ [ "species_10687614", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10689161": { "compartment": "compartment_7660", "id": "reaction_10689161", "reactome": "R-PFA-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688696", "species_30595" ], "products": [ "species_113541", "species_10688727" ], "modifiers": [ [ "species_10687614", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "species_110577", "species_29358", "species_29494", "species_29438", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10694756": { "compartment": "compartment_70101", "id": "reaction_10694756", "reactome": "R-PFA-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5357707", "species_113592" ], "products": [ "species_111294", "species_29372", "species_5357652" ], "modifiers": [ [ "species_10689792", "catalyst" ] ], "additional_components": [ "species_29926", "Q7K6A4", "PF3D7_0922200", "species_74126" ] }, "reaction_10703615": { "compartment": "compartment_876", "id": "reaction_10703615", "reactome": "R-PFA-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10703611" ], "products": [ "species_10703613" ], "modifiers": [], "additional_components": [ "Q8I1Z1", "PF3D7_0403800", "C0H4R4", "PF3D7_1120400", "Q8IIG3", "PF3D7_1120400", "Q8I1Z1", "PF3D7_0403800", "C0H4R4", "PF3D7_1120400", "Q8IIG3", "PF3D7_1120400" ] }, "reaction_10703582": { "compartment": "compartment_70101", "id": "reaction_10703582", "reactome": "R-PFA-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703578", "species_9653479" ], "products": [ "species_10703580" ], "modifiers": [], "additional_components": [ "Q8I503", "PF3D7_1242600", "Q8IHP6", "PF3D7_1147500", "Q8I503", "PF3D7_1242600", "Q8IHP6", "PF3D7_1147500" ] }, "reaction_10693680": { "compartment": "compartment_70101", "id": "reaction_10693680", "reactome": "R-PFA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1474124" ], "products": [ "species_1475054", "species_1474179" ], "modifiers": [ [ "species_10693677", "catalyst" ] ], "additional_components": [ "species_216785", "C6KTB6", "PF3D7_0628000" ] }, "reaction_10693669": { "compartment": "compartment_70101", "id": "reaction_10693669", "reactome": "R-PFA-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10693666", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "Q8I5H7", "PF3D7_1224000" ] }, "reaction_10693931": { "compartment": "compartment_70101", "id": "reaction_10693931", "reactome": "R-PFA-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690537", "species_1497857" ], "products": [ "species_29870", "species_10693929" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "species_1497857", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10693695": { "compartment": "compartment_70101", "id": "reaction_10693695", "reactome": "R-PFA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693684" ], "products": [ "species_10693677", "species_29370" ], "modifiers": [ [ "species_10693692", "catalyst" ] ], "additional_components": [ "C6KTB6", "PF3D7_0628000", "species_216785", "C6KTB6", "PF3D7_0628000", "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800" ] }, "reaction_10691489": { "compartment": "compartment_70101", "id": "reaction_10691489", "reactome": "R-PFA-426240", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114519" ], "products": [ "species_76108", "species_29370" ], "modifiers": [ [ "species_10691486", "catalyst" ] ], "additional_components": [ "Q8IKC5", "PF3D7_1471400", "Q8I2K9", "PF3D7_1471400" ] }, "reaction_10698647": { "compartment": "compartment_876", "id": "reaction_10698647", "reactome": "R-PFA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694509" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10698644", "catalyst" ] ], "additional_components": [ "PF3D7_0728700" ] }, "reaction_10692642": { "compartment": "compartment_70101", "id": "reaction_10692642", "reactome": "R-PFA-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692638", "species_10692633" ], "products": [ "species_10692640" ], "modifiers": [], "additional_components": [ "PF3D7_0517600", "PF3D7_0528500", "Q8I3I2", "PF3D7_0528500", "Q8I3T2", "PF3D7_0517600" ] }, "reaction_10693489": { "compartment": "compartment_5460", "id": "reaction_10693489", "reactome": "R-PFA-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113581", "species_113525" ], "modifiers": [ [ "species_10693486", "catalyst" ] ], "additional_components": [ "PF3D7_1008900" ] }, "reaction_10693458": { "compartment": "compartment_70101", "id": "reaction_10693458", "reactome": "R-PFA-984689", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693431" ], "products": [ "species_10693433" ], "modifiers": [], "additional_components": [ "Q8I4X5", "PF3D7_1245600", "Q8I5U0", "PF3D7_1245600", "Q8I4X5", "PF3D7_1245600", "Q8I5U0", "PF3D7_1245600" ] }, "reaction_10693456": { "compartment": "compartment_70101", "id": "reaction_10693456", "reactome": "R-PFA-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693410" ], "products": [ "species_10693412" ], "modifiers": [], "additional_components": [ "PF3D7_0317500", "O77382", "PF3D7_0317500" ] }, "reaction_10693480": { "compartment": "compartment_7660", "id": "reaction_10693480", "reactome": "R-PFA-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693476", "species_10693463" ], "products": [ "species_10693478" ], "modifiers": [], "additional_components": [ "Q8IDZ1", "PF3D7_1333700", "C6KSV0", "PF3D7_0617900", "C6KT19", "PF3D7_0617900", "PF3D7_1220900", "Q8I5K4", "PF3D7_1220900", "Q8IDZ1", "PF3D7_1333700", "C6KSV0", "PF3D7_0617900", "C6KT19", "PF3D7_0617900" ] }, "reaction_10703621": { "compartment": "compartment_70101", "id": "reaction_10703621", "reactome": "R-PFA-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703617" ], "products": [ "species_10703619" ], "modifiers": [], "additional_components": [ "PF3D7_0917100", "PF3D7_0917100" ] }, "reaction_10689008": { "compartment": "compartment_7660", "id": "reaction_10689008", "reactome": "R-PFA-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689003" ], "products": [ "species_5635947", "species_10689005" ], "modifiers": [ [ "species_10689003", "catalyst" ] ], "additional_components": [ "A0A143ZYC4", "PF3D7_1129500", "A0A143ZYC4", "PF3D7_1129500", "A0A143ZYC4", "PF3D7_1129500" ] }, "reaction_10689024": { "compartment": "compartment_7660", "id": "reaction_10689024", "reactome": "R-PFA-110250", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689021" ], "products": [ "species_110249", "species_10689014" ], "modifiers": [ [ "species_10689021", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10689031": { "compartment": "compartment_7660", "id": "reaction_10689031", "reactome": "R-PFA-110251", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689028" ], "products": [ "species_29850", "species_10689014" ], "modifiers": [ [ "species_10689028", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10689017": { "compartment": "compartment_7660", "id": "reaction_10689017", "reactome": "R-PFA-110248", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689012" ], "products": [ "species_10689014", "species_30947" ], "modifiers": [ [ "species_10689012", "catalyst" ] ], "additional_components": [ "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100", "Q8IKG6", "PF3D7_1467100" ] }, "reaction_10688985": { "compartment": "compartment_7660", "id": "reaction_10688985", "reactome": "R-PFA-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688980" ], "products": [ "species_10688982", "species_110242" ], "modifiers": [ [ "species_10688980", "catalyst" ] ], "additional_components": [ "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100", "Q8I2Y2", "PF3D7_0917100" ] }, "reaction_10689062": { "compartment": "compartment_7660", "id": "reaction_10689062", "reactome": "R-PFA-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10689051" ], "products": [ "species_10689059" ], "modifiers": [ [ "species_10689051", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10689109": { "compartment": "compartment_7660", "id": "reaction_10689109", "reactome": "R-PFA-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689067", "species_10689072" ], "products": [ "species_10689074" ], "modifiers": [], "additional_components": [ "PF3D7_1037000", "PF3D7_1023400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10689083": { "compartment": "compartment_7660", "id": "reaction_10689083", "reactome": "R-PFA-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689076" ], "products": [ "species_10689080", "species_113541", "species_10689074" ], "modifiers": [ [ "species_10689076", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10697018": { "compartment": "compartment_7660", "id": "reaction_10697018", "reactome": "R-PFA-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689074", "species_10689059" ], "products": [ "species_10689076" ], "modifiers": [], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000" ] }, "reaction_10689053": { "compartment": "compartment_7660", "id": "reaction_10689053", "reactome": "R-PFA-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689036", "species_10689049" ], "products": [ "species_10689051" ], "modifiers": [], "additional_components": [ "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697056": { "compartment": "compartment_7660", "id": "reaction_10697056", "reactome": "R-PFA-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697052", "species_10689135" ], "products": [ "species_10697054" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697153": { "compartment": "compartment_7660", "id": "reaction_10697153", "reactome": "R-PFA-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10697144" ], "products": [ "species_10697150", "species_113541" ], "modifiers": [ [ "species_10697144", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697162": { "compartment": "compartment_7660", "id": "reaction_10697162", "reactome": "R-PFA-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697150", "species_30555" ], "products": [ "species_10689036", "species_113541", "species_10697159", "species_10689074" ], "modifiers": [ [ "species_10697150", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "PF3D7_0910500", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_29926", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8I347", "PF3D7_0910500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10689107": { "compartment": "compartment_7660", "id": "reaction_10689107", "reactome": "R-PFA-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689097" ], "products": [ "species_113541", "species_10689104" ], "modifiers": [ [ "species_10689097", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697094": { "compartment": "compartment_7660", "id": "reaction_10697094", "reactome": "R-PFA-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697090", "species_10697074" ], "products": [ "species_10697092" ], "modifiers": [], "additional_components": [ "Q8ILR6", "PF3D7_1418000", "C6KT34", "PF3D7_0619400", "Q8I426", "PF3D7_0507700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400", "Q8ILR6", "PF3D7_1418000", "C6KT34", "PF3D7_0619400", "Q8I426", "PF3D7_0507700" ] }, "reaction_10697096": { "compartment": "compartment_7660", "id": "reaction_10697096", "reactome": "R-PFA-5654986", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697072", "species_10689104" ], "products": [ "species_10697074" ], "modifiers": [], "additional_components": [ "PF3D7_1338400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IDU9", "PF3D7_1338400" ] }, "reaction_10689100": { "compartment": "compartment_7660", "id": "reaction_10689100", "reactome": "R-PFA-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29604", "species_10689091" ], "products": [ "species_10689097", "species_113541" ], "modifiers": [ [ "species_10689091", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400" ] }, "reaction_10697125": { "compartment": "compartment_7660", "id": "reaction_10697125", "reactome": "R-PFA-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697116", "species_30555" ], "products": [ "species_113541", "species_10697122" ], "modifiers": [ [ "species_10697116", "catalyst" ] ], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8I347", "PF3D7_0910500" ] }, "reaction_10697134": { "compartment": "compartment_7660", "id": "reaction_10697134", "reactome": "R-PFA-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10697122" ], "products": [ "species_10689036", "species_10697131", "species_113541", "species_10689074" ], "modifiers": [ [ "species_10697122", "catalyst" ] ], "additional_components": [ "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500", "PF3D7_0910500", "species_1981162", "species_29926", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8IJH1", "PF3D7_1023400", "A0A143ZYZ7", "PF3D7_1037000", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "species_1981162", "species_29926", "Q8I347", "PF3D7_0910500" ] }, "reaction_10703478": { "compartment": "compartment_70101", "id": "reaction_10703478", "reactome": "R-PFA-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690526", "species_10703474" ], "products": [ "species_10703476" ], "modifiers": [], "additional_components": [ "species_74016", "P62203", "PF14_0323", "C0H482", "PF3D7_1450000", "Q8IKX5", "PF3D7_1450000", "C0H4K5", "PF3D7_1450000", "C6KSQ1", "PF3D7_1450000", "C0H482", "PF3D7_1450000", "Q8IKX5", "PF3D7_1450000", "C0H4K5", "PF3D7_1450000", "C6KSQ1", "PF3D7_1450000", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10703452": { "compartment": "compartment_70101", "id": "reaction_10703452", "reactome": "R-PFA-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10703445" ], "products": [ "species_29370", "species_10703449" ], "modifiers": [ [ "species_10703445", "catalyst" ] ], "additional_components": [ "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323", "Q8IL57", "PF3D7_1441300", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10703397": { "compartment": "compartment_7660", "id": "reaction_10703397", "reactome": "R-PFA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703385" ], "products": [ "species_10703395" ], "modifiers": [], "additional_components": [ "Q8I4W3", "PF3D7_1246900", "Q8I4W3", "PF3D7_1246900" ] }, "reaction_10690163": { "compartment": "compartment_70101", "id": "reaction_10690163", "reactome": "R-PFA-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193707", "species_29364" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690161": { "compartment": "compartment_70101", "id": "reaction_10690161", "reactome": "R-PFA-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690159": { "compartment": "compartment_70101", "id": "reaction_10690159", "reactome": "R-PFA-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_193707", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690157": { "compartment": "compartment_70101", "id": "reaction_10690157", "reactome": "R-PFA-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193724", "species_70106", "species_29364" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10702531": { "compartment": "compartment_70101", "id": "reaction_10702531", "reactome": "R-PFA-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10702528", "catalyst" ] ], "additional_components": [ "Q8II47", "PF3D7_1131800" ] }, "reaction_10690167": { "compartment": "compartment_70101", "id": "reaction_10690167", "reactome": "R-PFA-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_9617026" ], "products": [ "species_193829", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690165": { "compartment": "compartment_70101", "id": "reaction_10690165", "reactome": "R-PFA-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193829", "species_29364" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690171": { "compartment": "compartment_70101", "id": "reaction_10690171", "reactome": "R-PFA-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690169": { "compartment": "compartment_70101", "id": "reaction_10690169", "reactome": "R-PFA-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10702539": { "compartment": "compartment_70101", "id": "reaction_10702539", "reactome": "R-PFA-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_8868393", "species_1806234" ], "modifiers": [ [ "species_10702536", "catalyst" ] ], "additional_components": [ "PF3D7_1131800" ] }, "reaction_10690146": { "compartment": "compartment_70101", "id": "reaction_10690146", "reactome": "R-PFA-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690150": { "compartment": "compartment_70101", "id": "reaction_10690150", "reactome": "R-PFA-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191980", "species_70106", "species_29364" ], "products": [ "species_192030", "species_29366" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690148": { "compartment": "compartment_70101", "id": "reaction_10690148", "reactome": "R-PFA-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690141": { "compartment": "compartment_70101", "id": "reaction_10690141", "reactome": "R-PFA-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_192136", "species_29364" ], "products": [ "species_191980", "species_29366" ], "modifiers": [ [ "species_10690138", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690097": { "compartment": "compartment_70101", "id": "reaction_10690097", "reactome": "R-PFA-191322", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191324", "species_191362" ], "products": [ "species_111294", "species_191409" ], "modifiers": [ [ "species_10690091", "catalyst" ] ], "additional_components": [ "Q8II79", "PF3D7_1128400", "species_29926" ] }, "reaction_10690094": { "compartment": "compartment_70101", "id": "reaction_10690094", "reactome": "R-PFA-191303", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191409", "species_191362" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10690091", "catalyst" ] ], "additional_components": [ "Q8II79", "PF3D7_1128400", "species_29926" ] }, "reaction_10696462": { "compartment": "compartment_17957", "id": "reaction_10696462", "reactome": "R-PFA-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10696459", "catalyst" ] ], "additional_components": [ "PF3D7_1011300" ] }, "reaction_10700978": { "compartment": "compartment_17906", "id": "reaction_10700978", "reactome": "R-PFA-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10700973", "catalyst" ] ], "additional_components": [ "Q8I227", "PF3D7_0111900", "Q8IE73", "PF3D7_1324400" ] }, "reaction_10700975": { "compartment": "compartment_17927", "id": "reaction_10700975", "reactome": "R-PFA-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700971", "species_10700962" ], "products": [ "species_10700973" ], "modifiers": [], "additional_components": [ "Q8IE73", "PF3D7_1324400", "PF3D7_0111900", "Q8I227", "PF3D7_0111900", "Q8IE73", "PF3D7_1324400" ] }, "reaction_10703356": { "compartment": "compartment_70101", "id": "reaction_10703356", "reactome": "R-PFA-9020271", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024522" ], "products": [ "species_29356", "species_9024463", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10703366": { "compartment": "compartment_70101", "id": "reaction_10703366", "reactome": "R-PFA-9024993", "name": "EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_9025001" ], "products": [ "species_9025011" ], "modifiers": [ [ "species_10694550", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IM75", "PF3D7_1401300" ] }, "reaction_10703358": { "compartment": "compartment_70101", "id": "reaction_10703358", "reactome": "R-PFA-9020273", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024012" ], "products": [ "species_29356", "species_9024815", "species_111745" ], "modifiers": [ [ "species_10703349", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10696999": { "compartment": "compartment_7660", "id": "reaction_10696999", "reactome": "R-PFA-5649856", "name": "Oxidative damage to the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689130" ], "products": [ "species_10696997" ], "modifiers": [], "additional_components": [ "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600" ] }, "reaction_10689156": { "compartment": "compartment_7660", "id": "reaction_10689156", "reactome": "R-PFA-110371", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687076", "species_10689152" ], "products": [ "species_10689154" ], "modifiers": [], "additional_components": [ "PF3D7_1304100", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100" ] }, "reaction_10697012": { "compartment": "compartment_7660", "id": "reaction_10697012", "reactome": "R-PFA-5651805", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689154" ], "products": [ "species_10697009" ], "modifiers": [ [ "species_10689154", "catalyst" ] ], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "Q8IES4", "PF3D7_1304100", "O97240", "PF3D7_0305600", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q8IES4", "PF3D7_1304100" ] }, "reaction_10689148": { "compartment": "compartment_7660", "id": "reaction_10689148", "reactome": "R-PFA-110368", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10689145" ], "products": [ "species_10689141", "species_113541" ], "modifiers": [ [ "species_10689145", "catalyst" ] ], "additional_components": [ "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c", "P61074", "PF13_0328", "Q8IKK4", "PF3D7_1463200", "Q8I512", "PF3D7_1241700", "O96260", "PF3D7_0218000", "O96271", "PF3D7_0219600", "Q8IIQ1", "PF3D7_1111100", "C6S3I6", "PF3D7_1442100", "Q8IIN9", "PF3D7_1112400", "O97240", "PF3D7_0305600", "Q7K734", "PFD0420c" ] }, "reaction_10698360": { "compartment": "compartment_70101", "id": "reaction_10698360", "reactome": "R-PFA-5691512", "name": "APEH hydrolyses NAc-Ser-protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5691496", "species_29356" ], "products": [ "species_6785226", "species_5691517" ], "modifiers": [ [ "species_10698357", "catalyst" ] ], "additional_components": [ "species_5691517", "species_6785226", "PF3D7_0321500" ] }, "reaction_10700732": { "compartment": "compartment_70101", "id": "reaction_10700732", "reactome": "R-PFA-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10700710" ], "products": [ "species_10700717", "species_71285" ], "modifiers": [ [ "species_10700729", "catalyst" ] ], "additional_components": [ "Q8IIC9", "PF3D7_1123400", "species_29438", "O96203", "PF3D7_0212300", "Q8IIC9", "PF3D7_1123400", "species_29438", "O96203", "PF3D7_0212300", "Q8IET4", "PF3D7_1303100", "Q8IM19", "PF3D7_1407500" ] }, "reaction_10703116": { "compartment": "compartment_13231", "id": "reaction_10703116", "reactome": "R-PFA-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703109" ], "products": [ "species_10703107" ], "modifiers": [], "additional_components": [ "PF3D7_0416500", "PF3D7_0416500" ] }, "reaction_10694753": { "compartment": "compartment_70101", "id": "reaction_10694753", "reactome": "R-PFA-2395872", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395868" ], "products": [ "species_111294", "species_2395878" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10694751": { "compartment": "compartment_70101", "id": "reaction_10694751", "reactome": "R-PFA-2395849", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10694748": { "compartment": "compartment_70101", "id": "reaction_10694748", "reactome": "R-PFA-2395818", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395822" ], "products": [ "species_111294", "species_2395855" ], "modifiers": [ [ "species_10694745", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IDK8", "PF3D7_1349100" ] }, "reaction_10698420": { "compartment": "compartment_5460", "id": "reaction_10698420", "reactome": "R-PFA-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10698407" ], "products": [ "species_113529", "species_29362", "species_10698401" ], "modifiers": [ [ "species_10698417", "catalyst" ] ], "additional_components": [ "Q8II35", "PF3D7_1132900", "CHEBI:50746", "PF3D7_1132900", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10698415": { "compartment": "compartment_5460", "id": "reaction_10698415", "reactome": "R-PFA-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10698405" ], "products": [ "species_5693978", "species_5693984", "species_10698407" ], "modifiers": [ [ "species_10698412", "catalyst" ] ], "additional_components": [ "Q8II35", "PF3D7_1132900", "CHEBI:14949", "Q8II35", "PF3D7_1132900", "CHEBI:50746", "PF3D7_1365500" ] }, "reaction_10697634": { "compartment": "compartment_70101", "id": "reaction_10697634", "reactome": "R-PFA-5688797", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10689705" ], "products": [ "species_10689705", "species_10689703" ], "modifiers": [ [ "species_10697631", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F0", "PF3D7_1226800", "Q8IIP4", "PF3D7_1111900" ] }, "reaction_10697618": { "compartment": "compartment_7660", "id": "reaction_10697618", "reactome": "R-PFA-5688786", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697614", "species_10697609" ], "products": [ "species_10697616" ], "modifiers": [], "additional_components": [ "PF3D7_1226800", "Q8IJS8", "PF3D7_1011700", "Q8IJS8", "PF3D7_1011700", "Q8I5F0", "PF3D7_1226800" ] }, "reaction_10698080": { "compartment": "compartment_70101", "id": "reaction_10698080", "reactome": "R-PFA-5689111", "name": "PARK2 autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698072", "species_10693227" ], "products": [ "species_10697641" ], "modifiers": [ [ "species_10693227", "catalyst" ] ], "additional_components": [ "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_0303800", "PF3D7_0303800", "PF3D7_0303800" ] }, "reaction_10697638": { "compartment": "compartment_7660", "id": "reaction_10697638", "reactome": "R-PFA-5688834", "name": "ATXN3 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697614", "species_10697078" ], "products": [ "species_10697636" ], "modifiers": [], "additional_components": [ "PF3D7_1226800", "C6KT34", "PF3D7_0619400", "C6KT34", "PF3D7_0619400", "Q8I5F0", "PF3D7_1226800" ] }, "reaction_10698075": { "compartment": "compartment_70101", "id": "reaction_10698075", "reactome": "R-PFA-5688837", "name": "ATXN3 deubiquitinates polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10697643" ], "products": [ "species_10697645", "species_10698072" ], "modifiers": [ [ "species_10697643", "catalyst" ] ], "additional_components": [ "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800" ] }, "reaction_10698077": { "compartment": "compartment_70101", "id": "reaction_10698077", "reactome": "R-PFA-5689085", "name": "ATXN3 binds polyUb-PARK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697641", "species_10697620" ], "products": [ "species_10697643" ], "modifiers": [], "additional_components": [ "PF3D7_0303800", "PF3D7_1226800", "Q8I5F0", "PF3D7_1226800", "O97226", "PF3D7_0303800" ] }, "reaction_10703328": { "compartment": "compartment_70101", "id": "reaction_10703328", "reactome": "R-PFA-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10696164", "catalyst" ] ], "additional_components": [ "PF3D7_1432100" ] }, "reaction_10699253": { "compartment": "compartment_70101", "id": "reaction_10699253", "reactome": "R-PFA-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29708", "species_29450" ], "modifiers": [ [ "species_10699250", "catalyst" ] ], "additional_components": [ "species_216785", "C0H490", "PF3D7_0406400" ] }, "reaction_10698430": { "compartment": "compartment_70101", "id": "reaction_10698430", "reactome": "R-PFA-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694074", "species_29450" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10698427", "catalyst" ] ], "additional_components": [ "species_216785", "Q8IIM5", "PF3D7_1113700" ] }, "reaction_10696882": { "compartment": "compartment_70101", "id": "reaction_10696882", "reactome": "R-PFA-5618328", "name": "ATAT acetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691147", "species_76183" ], "products": [ "species_10696874", "species_76194" ], "modifiers": [ [ "species_10696879", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29420", "species_29438", "PFI1220w" ] }, "reaction_10696885": { "compartment": "compartment_70101", "id": "reaction_10696885", "reactome": "R-PFA-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696874", "species_76194" ], "products": [ "species_10691147", "species_76183" ], "modifiers": [ [ "species_10696504", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29420", "species_29438", "PF3D7_1008000" ] }, "reaction_10697600": { "compartment": "compartment_17927", "id": "reaction_10697600", "reactome": "R-PFA-5688294", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688282", "species_10697590" ], "products": [ "species_5688281", "species_10689386", "species_5688340" ], "modifiers": [ [ "species_10697597", "catalyst" ] ], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "species_216785", "Q8IE47", "PF13_0152" ] }, "reaction_10689159": { "compartment": "compartment_70101", "id": "reaction_10689159", "reactome": "R-PFA-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10688285", "catalyst" ], [ "species_29372", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IE40", "PF3D7_1327800", "Q8IE67", "PF3D7_1327800" ] }, "reaction_10688292": { "compartment": "compartment_70101", "id": "reaction_10688292", "reactome": "R-PFA-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_113592" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10688289", "catalyst" ] ], "additional_components": [ "Q8IE40", "PF3D7_1327800", "Q8IE67", "PF3D7_1327800" ] }, "reaction_10689586": { "compartment": "compartment_7660", "id": "reaction_10689586", "reactome": "R-PFA-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10688553" ], "modifiers": [], "additional_components": [ "PF3D7_1444300" ] }, "reaction_10693747": { "compartment": "compartment_12045", "id": "reaction_10693747", "reactome": "R-PFA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500596" ], "products": [ "species_1498728", "species_1524021" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693744": { "compartment": "compartment_12045", "id": "reaction_10693744", "reactome": "R-PFA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500594" ], "products": [ "species_1524021", "species_1500596" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693735": { "compartment": "compartment_12045", "id": "reaction_10693735", "reactome": "R-PFA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_1500596" ], "products": [ "species_76116", "species_1500594" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693737": { "compartment": "compartment_12045", "id": "reaction_10693737", "reactome": "R-PFA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728" ], "products": [ "species_76116", "species_1500596" ], "modifiers": [ [ "species_10693732", "catalyst" ] ], "additional_components": [ "O96266", "PF3D7_0218600" ] }, "reaction_10693759": { "compartment": "compartment_12045", "id": "reaction_10693759", "reactome": "R-PFA-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10688689", "catalyst" ] ], "additional_components": [ "O97295", "PF3D7_0322300" ] }, "reaction_10703201": { "compartment": "compartment_70101", "id": "reaction_10703201", "reactome": "R-PFA-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10703198", "catalyst" ] ], "additional_components": [ "PF3D7_1468300" ] }, "reaction_10691072": { "compartment": "compartment_70101", "id": "reaction_10691072", "reactome": "R-PFA-379387", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10691067", "catalyst" ], [ "species_10691070", "inhibitor" ] ], "additional_components": [ "PF3D7_1468300", "Q8IKF4", "PF3D7_1468300" ] }, "reaction_10703636": { "compartment": "compartment_876", "id": "reaction_10703636", "reactome": "R-PFA-9679775", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691067", "species_9679778" ], "products": [ "species_10691070" ], "modifiers": [], "additional_components": [ "PF3D7_1468300", "Q8IKF4", "PF3D7_1468300" ] }, "reaction_10701636": { "compartment": "compartment_20699", "id": "reaction_10701636", "reactome": "R-PFA-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701627" ], "products": [ "species_10701633" ], "modifiers": [ [ "species_10701627", "catalyst" ] ], "additional_components": [ "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420", "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900" ] }, "reaction_10701609": { "compartment": "compartment_20699", "id": "reaction_10701609", "reactome": "R-PFA-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10701605" ], "products": [ "species_10701607" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "Q8IE08", "PF3D7_1332000", "C0H5D3", "PF3D7_1324700", "Q8IKE6", "PF3D7_1469100", "Q8IE08", "PF3D7_1332000", "C0H5D3", "PF3D7_1324700", "Q8IKE6", "PF3D7_1469100", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701629": { "compartment": "compartment_20699", "id": "reaction_10701629", "reactome": "R-PFA-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701617", "species_10694050" ], "products": [ "species_10701627" ], "modifiers": [], "additional_components": [ "Q8IL42", "PF3D7_1442900", "species_29438", "Q7KQL3", "PF10_0203", "species_29438", "Q7KQL3", "PF10_0203", "Q8IL42", "PF3D7_1442900" ] }, "reaction_10703441": { "compartment": "compartment_70101", "id": "reaction_10703441", "reactome": "R-PFA-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703437", "species_10703409" ], "products": [ "species_10703439" ], "modifiers": [], "additional_components": [ "Q8I599", "PF3D7_1232300", "O96183", "PF3D7_0210000", "Q8I655", "PF3D7_0219400.1", "Q8IL71", "PF3D7_1439800", "Q8IE08", "PF3D7_1332000", "C0H4S2", "PF3D7_0806300", "C0H4W6", "PF3D7_0821800", "O77346", "PF3D7_0312200", "O77346", "PF3D7_0312200", "Q8I599", "PF3D7_1232300", "O96183", "PF3D7_0210000", "Q8I655", "PF3D7_0219400.1", "Q8IL71", "PF3D7_1439800", "Q8IE08", "PF3D7_1332000", "C0H4S2", "PF3D7_0806300", "C0H4W6", "PF3D7_0821800" ] }, "reaction_10694386": { "compartment": "compartment_70616", "id": "reaction_10694386", "reactome": "R-PFA-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694380", "species_10694378", "species_10694353" ], "products": [ "species_10694384" ], "modifiers": [], "additional_components": [ "PF3D7_1368600", "Q8IJ34", "PF3D7_1037300", "Q8ID24", "PF3D7_1368600", "Q8I5W2", "PF3D7_1208600", "PF3D7_0627400", "C6KTB0", "PF3D7_0627400", "Q8IJ34", "PF3D7_1037300", "Q8ID24", "PF3D7_1368600", "Q8I5W2", "PF3D7_1208600" ] }, "reaction_10687270": { "compartment": "compartment_70101", "id": "reaction_10687270", "reactome": "R-PFA-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29448", "species_29472" ], "products": [ "species_111294", "species_29404", "species_29642", "species_76577" ], "modifiers": [ [ "species_10687267", "catalyst" ] ], "additional_components": [ "O77330", "PF3D7_0309500" ] }, "reaction_10687260": { "compartment": "compartment_5460", "id": "reaction_10687260", "reactome": "R-PFA-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113587", "species_113552" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10703196": { "compartment": "compartment_5460", "id": "reaction_10703196", "reactome": "R-PFA-8954468", "name": "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113553" ], "products": [ "species_29374", "species_8954466", "species_113529" ], "modifiers": [ [ "species_10703193", "catalyst" ] ], "additional_components": [ "PF3D7_1437000" ] }, "reaction_10691653": { "compartment": "compartment_70101", "id": "reaction_10691653", "reactome": "R-PFA-429714", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10691634" ], "products": [ "species_29370", "species_10691638" ], "modifiers": [ [ "species_10691650", "catalyst" ] ], "additional_components": [ "PF3D7_0915800", "PF3D7_0915800", "Q8IHZ9", "PF3D7_1136500.1", "C6S3F7", "PF3D7_1136500.2" ] }, "reaction_10691668": { "compartment": "compartment_20699", "id": "reaction_10691668", "reactome": "R-PFA-429798", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_428270" ], "products": [ "species_429773", "species_429789" ], "modifiers": [ [ "species_10691665", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10691663": { "compartment": "compartment_876", "id": "reaction_10691663", "reactome": "R-PFA-429786", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_429807" ], "products": [ "species_429776", "species_112275" ], "modifiers": [ [ "species_10691660", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10691582": { "compartment": "compartment_70101", "id": "reaction_10691582", "reactome": "R-PFA-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_428163" ], "products": [ "species_428126", "species_76194" ], "modifiers": [ [ "species_10691579", "catalyst" ] ], "additional_components": [ "Q8IM57", "PF3D7_1403700" ] }, "reaction_10703662": { "compartment": "compartment_70101", "id": "reaction_10703662", "reactome": "R-PFA-9695890", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_419305" ], "modifiers": [ [ "species_10703659", "catalyst" ] ], "additional_components": [ "C6KSY4", "PF3D7_0916000", "Q8I2Z2", "PF3D7_0916000" ] }, "reaction_10703229": { "compartment": "compartment_12045", "id": "reaction_10703229", "reactome": "R-PFA-8959462", "name": "SAMD8 transforms PE and CERA to CPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8959490", "species_8959486" ], "products": [ "species_8959463" ], "modifiers": [ [ "species_10703226", "catalyst" ] ], "additional_components": [ "PF3D7_0625100" ] }, "reaction_10692484": { "compartment": "compartment_70101", "id": "reaction_10692484", "reactome": "R-PFA-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10692481", "catalyst" ] ], "additional_components": [ "PF3D7_0801800" ] }, "reaction_10692090": { "compartment": "compartment_70101", "id": "reaction_10692090", "reactome": "R-PFA-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10692087", "catalyst" ] ], "additional_components": [ "Q8IJM5", "PF3D7_1017400" ] }, "reaction_10692499": { "compartment": "compartment_70101", "id": "reaction_10692499", "reactome": "R-PFA-548814", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29508", "species_200993" ], "products": [ "species_113528", "species_548812", "species_76194" ], "modifiers": [ [ "species_10692496", "catalyst" ] ], "additional_components": [ "Q8I251", "PF3D7_0109300" ] }, "reaction_10690466": { "compartment": "compartment_70101", "id": "reaction_10690466", "reactome": "R-PFA-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_111294", "species_29356", "species_200993", "species_76577" ], "modifiers": [ [ "species_10690463", "catalyst" ] ], "additional_components": [ "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10692511": { "compartment": "compartment_70101", "id": "reaction_10692511", "reactome": "R-PFA-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_428139", "species_29366" ], "modifiers": [ [ "species_10692508", "catalyst" ] ], "additional_components": [ "Q8II05", "PF3D7_1135900" ] }, "reaction_10697326": { "compartment": "compartment_12045", "id": "reaction_10697326", "reactome": "R-PFA-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_29356", "species_5676634" ], "modifiers": [ [ "species_10697323", "catalyst" ] ], "additional_components": [ "C0H5F1", "PF3D7_1331600" ] }, "reaction_10692492": { "compartment": "compartment_70101", "id": "reaction_10692492", "reactome": "R-PFA-548800", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_29508" ], "products": [ "species_113528", "species_548816", "species_76194" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10698277": { "compartment": "compartment_12045", "id": "reaction_10698277", "reactome": "R-PFA-5690565", "name": "SCD desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10698274", "catalyst" ] ], "additional_components": [ "Q8I0W9", "PF3D7_0511200" ] }, "reaction_10701599": { "compartment": "compartment_12045", "id": "reaction_10701599", "reactome": "R-PFA-8847579", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10701596", "catalyst" ] ], "additional_components": [ "Q8I0W9", "PF3D7_0511200" ] }, "reaction_10698099": { "compartment": "compartment_5460", "id": "reaction_10698099", "reactome": "R-PFA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690540", "species_113521" ], "products": [ "species_29374", "species_5690519" ], "modifiers": [ [ "species_10698096", "catalyst" ] ], "additional_components": [ "species_164991", "CHEBI:61907", "species_174602", "CHEBI:59554", "PF3D7_0217900" ] }, "reaction_10701663": { "compartment": "compartment_70101", "id": "reaction_10701663", "reactome": "R-PFA-8848250", "name": "ACBD6 binds LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164991", "species_10701659" ], "products": [ "species_10701661" ], "modifiers": [], "additional_components": [ "Q8IBL1", "PF3D7_1119000", "Q8IIH7", "PF3D7_1119000", "Q8IBL1", "PF3D7_1119000", "Q8IIH7", "PF3D7_1119000", "species_164991" ] }, "reaction_10694426": { "compartment": "compartment_17957", "id": "reaction_10694426", "reactome": "R-PFA-2046088", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046052", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046051", "species_162743", "species_159751" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10694424": { "compartment": "compartment_12045", "id": "reaction_10694424", "reactome": "R-PFA-2046085", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_2046056", "species_162743" ], "products": [ "species_2046064", "species_2046049", "species_2046062" ], "modifiers": [ [ "species_10694421", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10694430": { "compartment": "compartment_12045", "id": "reaction_10694430", "reactome": "R-PFA-2046098", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_162743", "species_2046044" ], "products": [ "species_2046064", "species_2046049", "species_2046063" ], "modifiers": [ [ "species_10694421", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I3L4", "PF3D7_1238800", "Q8I535", "PF3D7_1238800" ] }, "reaction_10694428": { "compartment": "compartment_17957", "id": "reaction_10694428", "reactome": "R-PFA-2046094", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046042", "species_113601" ], "products": [ "species_113519", "species_113564", "species_162743", "species_159751", "species_2046045" ], "modifiers": [ [ "species_10692489", "catalyst" ] ], "additional_components": [ "PF3D7_0109300" ] }, "reaction_10694555": { "compartment": "compartment_70101", "id": "reaction_10694555", "reactome": "R-PFA-2161999", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142811", "species_29450" ], "products": [ "species_29356", "species_2142678", "species_111745" ], "modifiers": [ [ "species_10694540", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10694543": { "compartment": "compartment_70101", "id": "reaction_10694543", "reactome": "R-PFA-2161959", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_2142790" ], "products": [ "species_29356", "species_2142716", "species_111745" ], "modifiers": [ [ "species_10694540", "catalyst" ] ], "additional_components": [ "PF3D7_1212000" ] }, "reaction_10694529": { "compartment": "compartment_70101", "id": "reaction_10694529", "reactome": "R-PFA-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10694534": { "compartment": "compartment_70101", "id": "reaction_10694534", "reactome": "R-PFA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_879629" ], "modifiers": [ [ "species_10694531", "catalyst" ] ], "additional_components": [ "Q8ILQ7", "PF14_0187", "species_29450" ] }, "reaction_10694526": { "compartment": "compartment_70101", "id": "reaction_10694526", "reactome": "R-PFA-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_265283", "species_29364" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10690909": { "compartment": "compartment_70101", "id": "reaction_10690909", "reactome": "R-PFA-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10690906", "catalyst" ] ], "additional_components": [ "C0H473", "PF3D7_1453700", "Q8IKU1", "PF3D7_1453700", "A0A144A1J3", "PF3D7_1453700" ] }, "reaction_10693717": { "compartment": "compartment_12045", "id": "reaction_10693717", "reactome": "R-PFA-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10693708", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693711": { "compartment": "compartment_12045", "id": "reaction_10693711", "reactome": "R-PFA-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498740" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10693708", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693714": { "compartment": "compartment_12045", "id": "reaction_10693714", "reactome": "R-PFA-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10693703", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693755": { "compartment": "compartment_12045", "id": "reaction_10693755", "reactome": "R-PFA-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10693752", "catalyst" ] ], "additional_components": [ "PF3D7_1358000" ] }, "reaction_10693706": { "compartment": "compartment_12045", "id": "reaction_10693706", "reactome": "R-PFA-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_975614" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10693703", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693739": { "compartment": "compartment_12045", "id": "reaction_10693739", "reactome": "R-PFA-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498738" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693723": { "compartment": "compartment_12045", "id": "reaction_10693723", "reactome": "R-PFA-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693757": { "compartment": "compartment_12045", "id": "reaction_10693757", "reactome": "R-PFA-1482887", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10693752", "catalyst" ] ], "additional_components": [ "PF3D7_1358000" ] }, "reaction_10693720": { "compartment": "compartment_12045", "id": "reaction_10693720", "reactome": "R-PFA-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498724" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693741": { "compartment": "compartment_12045", "id": "reaction_10693741", "reactome": "R-PFA-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498722" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10688567", "catalyst" ] ], "additional_components": [ "Q8I310", "PF3D7_0914200", "Q8IKZ8", "PF3D7_1447700" ] }, "reaction_10693923": { "compartment": "compartment_70101", "id": "reaction_10693923", "reactome": "R-PFA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10693920", "catalyst" ] ], "additional_components": [ "Q8IIB7", "PF3D7_1124600", "Q8IM71", "PF3D7_1401800" ] }, "reaction_10693778": { "compartment": "compartment_12045", "id": "reaction_10693778", "reactome": "R-PFA-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_1500581", "species_109395" ], "modifiers": [ [ "species_10693775", "catalyst" ] ], "additional_components": [ "C6KTB9", "PF3D7_0628300.1", "species_29926", "species_1981162" ] }, "reaction_10693889": { "compartment": "compartment_12045", "id": "reaction_10693889", "reactome": "R-PFA-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428686", "species_110614" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10693886", "catalyst" ] ], "additional_components": [ "Q8IDM2", "PF3D7_1347700" ] }, "reaction_10693900": { "compartment": "compartment_12045", "id": "reaction_10693900", "reactome": "R-PFA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10693897", "catalyst" ] ], "additional_components": [ "species_29926", "O77317", "PF3D7_0303200" ] }, "reaction_10693906": { "compartment": "compartment_20699", "id": "reaction_10693906", "reactome": "R-PFA-1483211", "name": "PC:PITPNB is transported from the Golgi membrane to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693849" ], "products": [ "species_10693904" ], "modifiers": [], "additional_components": [ "Q8IDI9", "PF3D7_1351000", "species_194276", "species_194276", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693910": { "compartment": "compartment_12045", "id": "reaction_10693910", "reactome": "R-PFA-1483219", "name": "PC is exchanged with PI by PITPNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_10693904" ], "products": [ "species_426925", "species_10693908" ], "modifiers": [], "additional_components": [ "species_194276", "Q8IDI9", "PF3D7_1351000", "species_1806199", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693925": { "compartment": "compartment_12045", "id": "reaction_10693925", "reactome": "R-PFA-1483229", "name": "PI:PITPNB is transported from the ER membrane to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693908" ], "products": [ "species_10693847" ], "modifiers": [], "additional_components": [ "species_1806199", "Q8IDI9", "PF3D7_1351000", "species_1806199", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10703182": { "compartment": "compartment_984", "id": "reaction_10703182", "reactome": "R-PFA-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2173763" ], "products": [ "species_8954142", "species_8952253" ], "modifiers": [ [ "species_10703179", "catalyst" ] ], "additional_components": [ "PF3D7_0629300" ] }, "reaction_10693795": { "compartment": "compartment_12045", "id": "reaction_10693795", "reactome": "R-PFA-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_426639", "species_109395" ], "modifiers": [ [ "species_10693792", "catalyst" ] ], "additional_components": [ "species_29926", "species_1981162", "C0H5B7", "PF3D7_1315600" ] }, "reaction_10702550": { "compartment": "compartment_70101", "id": "reaction_10702550", "reactome": "R-PFA-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_1602448" ], "products": [ "species_426755", "species_426658" ], "modifiers": [ [ "species_10702547", "catalyst" ] ], "additional_components": [ "Q8IAY0", "PF3D7_0814400", "Q8IDI9", "PF3D7_1351000" ] }, "reaction_10693869": { "compartment": "compartment_12045", "id": "reaction_10693869", "reactome": "R-PFA-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_111294", "species_426955" ], "modifiers": [ [ "species_10693866", "catalyst" ] ], "additional_components": [ "species_29926", "Q8ILZ6", "PF3D7_1409900" ] }, "reaction_10693859": { "compartment": "compartment_12045", "id": "reaction_10693859", "reactome": "R-PFA-1483089", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_1500581" ], "products": [ "species_1498751", "species_1500646" ], "modifiers": [ [ "species_10693856", "catalyst" ] ], "additional_components": [ "PF3D7_1366800" ] }, "reaction_10693879": { "compartment": "compartment_12045", "id": "reaction_10693879", "reactome": "R-PFA-1483186", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_200736" ], "products": [ "species_264618", "species_1500646" ], "modifiers": [ [ "species_10693876", "catalyst" ] ], "additional_components": [ "PF3D7_1366800" ] }, "reaction_10693824": { "compartment": "compartment_70101", "id": "reaction_10693824", "reactome": "R-PFA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_113592" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10693821", "catalyst" ] ], "additional_components": [ "Q8IIB7", "PF3D7_1124600", "Q8IM71", "PF3D7_1401800" ] }, "reaction_10693840": { "compartment": "compartment_12045", "id": "reaction_10693840", "reactome": "R-PFA-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10693837", "catalyst" ] ], "additional_components": [ "Q8IEE9", "PF3D7_1316600" ] }, "reaction_10693769": { "compartment": "compartment_12045", "id": "reaction_10693769", "reactome": "R-PFA-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_426925", "species_109395" ], "modifiers": [ [ "species_10693766", "catalyst" ] ], "additional_components": [ "C6KTB9", "PF3D7_0628300.1", "species_29926", "species_1981162" ] }, "reaction_10693785": { "compartment": "compartment_20699", "id": "reaction_10693785", "reactome": "R-PFA-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_429785", "species_109395" ], "modifiers": [ [ "species_10693782", "catalyst" ] ], "additional_components": [ "species_29926", "species_1981162", "C6KTB9", "PF3D7_0628300.1" ] }, "reaction_10702281": { "compartment": "compartment_984", "id": "reaction_10702281", "reactome": "R-PFA-8865637", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8865642", "species_74113" ], "products": [ "species_8865629", "species_83910" ], "modifiers": [ [ "species_10702278", "catalyst" ] ], "additional_components": [ "PF3D7_0529200" ] }, "reaction_10693874": { "compartment": "compartment_70616", "id": "reaction_10693874", "reactome": "R-PFA-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524101", "species_110577" ], "products": [ "species_159450", "species_1524064" ], "modifiers": [ [ "species_10693871", "catalyst" ] ], "additional_components": [ "PF3D7_1409900" ] }, "reaction_10694115": { "compartment": "compartment_876", "id": "reaction_10694115", "reactome": "R-PFA-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_1806224", "species_29370" ], "modifiers": [ [ "species_10694015", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694018": { "compartment": "compartment_876", "id": "reaction_10694018", "reactome": "R-PFA-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_1806240", "species_29370" ], "modifiers": [ [ "species_10694015", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694081": { "compartment": "compartment_876", "id": "reaction_10694081", "reactome": "R-PFA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10694078", "catalyst" ] ], "additional_components": [ "A0A143ZZC6", "PF3D7_1111600", "Q8IC15", "PF3D7_0705500" ] }, "reaction_10693990": { "compartment": "compartment_876", "id": "reaction_10693990", "reactome": "R-PFA-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10693987", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694086": { "compartment": "compartment_876", "id": "reaction_10694086", "reactome": "R-PFA-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10694040", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694091": { "compartment": "compartment_876", "id": "reaction_10694091", "reactome": "R-PFA-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10694088", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694120": { "compartment": "compartment_876", "id": "reaction_10694120", "reactome": "R-PFA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10694117", "catalyst" ] ], "additional_components": [ "Q8I239", "PF3D7_0110600" ] }, "reaction_10694129": { "compartment": "compartment_876", "id": "reaction_10694129", "reactome": "R-PFA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10694126", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694132": { "compartment": "compartment_876", "id": "reaction_10694132", "reactome": "R-PFA-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10694088", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694043": { "compartment": "compartment_876", "id": "reaction_10694043", "reactome": "R-PFA-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10694040", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10702655": { "compartment": "compartment_20699", "id": "reaction_10702655", "reactome": "R-PFA-8870499", "name": "PLEKHA3,8 bind PI4P, ARF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690955", "species_10702651", "species_1806217" ], "products": [ "species_10702653" ], "modifiers": [], "additional_components": [ "PF10_0203", "Q8I2Z4", "PF3D7_0915800", "species_392417", "Q8I2Z4", "PF3D7_0915800", "Q7KQL3", "PF10_0203" ] }, "reaction_10694109": { "compartment": "compartment_12045", "id": "reaction_10694109", "reactome": "R-PFA-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806234" ], "products": [ "species_29372", "species_426639" ], "modifiers": [ [ "species_10694106", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694083": { "compartment": "compartment_20699", "id": "reaction_10694083", "reactome": "R-PFA-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10694112": { "compartment": "compartment_20699", "id": "reaction_10694112", "reactome": "R-PFA-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_29372", "species_1524146" ], "modifiers": [ [ "species_10694101", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694055": { "compartment": "compartment_20699", "id": "reaction_10694055", "reactome": "R-PFA-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10694052", "catalyst" ] ], "additional_components": [ "species_29438", "Q7KQL3", "PF10_0203", "Q8I406", "PF3D7_0509800" ] }, "reaction_10694023": { "compartment": "compartment_20699", "id": "reaction_10694023", "reactome": "R-PFA-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10694020", "catalyst" ] ], "additional_components": [ "PF3D7_0705500" ] }, "reaction_10694104": { "compartment": "compartment_20699", "id": "reaction_10694104", "reactome": "R-PFA-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806159" ], "products": [ "species_29372", "species_1524146" ], "modifiers": [ [ "species_10694101", "catalyst" ] ], "additional_components": [ "PF3D7_1354200" ] }, "reaction_10694124": { "compartment": "compartment_20699", "id": "reaction_10694124", "reactome": "R-PFA-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694122", "species_10694050" ], "products": [ "species_10694052" ], "modifiers": [], "additional_components": [ "PF3D7_0509800", "species_29438", "Q7KQL3", "PF10_0203", "species_29438", "Q7KQL3", "PF10_0203", "Q8I406", "PF3D7_0509800" ] }, "reaction_10694093": { "compartment": "compartment_172574", "id": "reaction_10694093", "reactome": "R-PFA-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_1806198", "species_29370" ], "modifiers": [ [ "species_10694061", "catalyst" ] ], "additional_components": [ "Q8IB64", "PF3D7_0823000", "species_1981162", "Q8I3V5", "PF3D7_0515300" ] }, "reaction_10688692": { "compartment": "compartment_70101", "id": "reaction_10688692", "reactome": "R-PFA-75900", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_76103" ], "products": [ "species_549167", "species_76194" ], "modifiers": [ [ "species_10688689", "catalyst" ] ], "additional_components": [ "O97295", "PF3D7_0322300" ] }, "reaction_10688586": { "compartment": "compartment_70101", "id": "reaction_10688586", "reactome": "R-PFA-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76116" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10688583", "catalyst" ] ], "additional_components": [ "Q8IDI4", "PF3D7_1351600" ] }, "reaction_10688682": { "compartment": "compartment_70101", "id": "reaction_10688682", "reactome": "R-PFA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76108", "species_29356" ], "products": [ "species_29372", "species_76103" ], "modifiers": [ [ "species_10688679", "catalyst" ] ], "additional_components": [ "O77317", "PF3D7_0303200" ] }, "reaction_10688368": { "compartment": "compartment_5460", "id": "reaction_10688368", "reactome": "R-PFA-73916", "name": "2 acetyl-CoA <=> acetoacetyl-CoA + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559" ], "products": [ "species_29374", "species_73871" ], "modifiers": [ [ "species_10687343", "catalyst" ] ], "additional_components": [ "Q8IKW7", "PF3D7_1450900" ] }, "reaction_10696583": { "compartment": "compartment_876", "id": "reaction_10696583", "reactome": "R-PFA-5340320", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5340315" ], "products": [ "species_5340299" ], "modifiers": [ [ "species_10696580", "catalyst" ] ], "additional_components": [ "PF3D7_0915800" ] }, "reaction_10693976": { "compartment": "compartment_876", "id": "reaction_10693976", "reactome": "R-PFA-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10693973", "catalyst" ] ], "additional_components": [ "Q8I537", "PF3D7_1238600", "species_29926" ] }, "reaction_10702983": { "compartment": "compartment_7660", "id": "reaction_10702983", "reactome": "R-PFA-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702972", "species_77087" ], "products": [ "species_77502", "species_10702975" ], "modifiers": [ [ "species_10702980", "catalyst" ] ], "additional_components": [ "PF3D7_0818900", "PF3D7_0818900", "PF3D7_1142700" ] }, "reaction_10703019": { "compartment": "compartment_70101", "id": "reaction_10703019", "reactome": "R-PFA-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10689442" ], "products": [ "species_71285", "species_10703011" ], "modifiers": [ [ "species_10703016", "catalyst" ] ], "additional_components": [ "PF3D7_1357000", "PF3D7_1357000", "PF3D7_0916600" ] }, "reaction_10703002": { "compartment": "compartment_70101", "id": "reaction_10703002", "reactome": "R-PFA-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696509", "species_71284" ], "products": [ "species_10702997", "species_71285" ], "modifiers": [ [ "species_10702999", "catalyst" ] ], "additional_components": [ "PF3D7_0619400", "PF3D7_0619400", "PF3D7_1142700" ] }, "reaction_10695844": { "compartment": "compartment_7660", "id": "reaction_10695844", "reactome": "R-PFA-4568914", "name": "SUMOylation of BLM with SUMO2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695835", "species_10695825" ], "products": [ "species_10695841", "species_10694930" ], "modifiers": [ [ "species_10695835", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_0918600", "PF3D7_0918600", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695934": { "compartment": "compartment_7660", "id": "reaction_10695934", "reactome": "R-PFA-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695924" ], "products": [ "species_10695932", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1432600", "Q8ILD6", "PF3D7_1432600", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695805": { "compartment": "compartment_7660", "id": "reaction_10695805", "reactome": "R-PFA-4551724", "name": "PIAS4 SUMOylates HERC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695789", "species_10694938" ], "products": [ "species_10695802", "species_10694930" ], "modifiers": [ [ "species_10695666", "catalyst" ] ], "additional_components": [ "Q8IDD6", "PF3D7_1356600", "Q8I5L0", "PF3D7_1356600", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I444", "PF3D7_0505800", "Q8I5L0", "PF3D7_1356600", "Q8IDD6", "PF3D7_1356600", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695984": { "compartment": "compartment_7660", "id": "reaction_10695984", "reactome": "R-PFA-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695974" ], "products": [ "species_10695982", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0925700", "Q8I444", "PF3D7_0505800", "Q7K6A1", "PF3D7_0925700", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695911": { "compartment": "compartment_7660", "id": "reaction_10695911", "reactome": "R-PFA-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10689874" ], "products": [ "species_10695909", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1105000", "Q8IIV2", "PF3D7_1105000", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695894": { "compartment": "compartment_7660", "id": "reaction_10695894", "reactome": "R-PFA-4570485", "name": "SUMOylation of Histone H4 with SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695833", "species_10689874" ], "products": [ "species_10694930", "species_10695891" ], "modifiers": [ [ "species_10695833", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1105000", "PF3D7_0915100", "PF3D7_1105000", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695957": { "compartment": "compartment_7660", "id": "reaction_10695957", "reactome": "R-PFA-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10693554" ], "products": [ "species_10694930", "species_10695955" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0925700", "PF3D7_0915100", "Q7K6A1", "PF3D7_0925700", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695888": { "compartment": "compartment_7660", "id": "reaction_10695888", "reactome": "R-PFA-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695877" ], "products": [ "species_10695886", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1008800", "Q8I444", "PF3D7_0505800", "Q8IJV7", "PF3D7_1008800", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695901": { "compartment": "compartment_7660", "id": "reaction_10695901", "reactome": "R-PFA-4570489", "name": "SUMOylation of NOP58 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695653", "species_10695877" ], "products": [ "species_10695898", "species_10694930" ], "modifiers": [ [ "species_10695653", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1008800", "PF3D7_1008800", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100" ] }, "reaction_10695715": { "compartment": "compartment_7660", "id": "reaction_10695715", "reactome": "R-PFA-4085992", "name": "SUMOylation of DAXX with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695018" ], "products": [ "species_10695713", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0807600", "Q8I444", "PF3D7_0505800", "C0H4S8", "PF3D7_0807600", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695633": { "compartment": "compartment_7660", "id": "reaction_10695633", "reactome": "R-PFA-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695614", "species_10694938" ], "products": [ "species_10695630", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I459", "PF3D7_1445900", "Q8IAR1", "PF3D7_1445900", "Q8IL13", "PF3D7_1445900", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "Q8I444", "PF3D7_0505800", "Q8IAR1", "PF3D7_1445900", "Q8I459", "PF3D7_1445900", "Q8IL13", "PF3D7_1445900", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10695664": { "compartment": "compartment_7660", "id": "reaction_10695664", "reactome": "R-PFA-3900194", "name": "PIAS1 SUMOylates DDX5 with SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695653", "species_10695635" ], "products": [ "species_10695656", "species_10694930" ], "modifiers": [ [ "species_10695661", "catalyst" ] ], "additional_components": [ "Q8I444", "PF3D7_0505800", "Q8I301", "PF3D7_0915100", "PF3D7_1445900", "PF3D7_1445900", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695694": { "compartment": "compartment_7660", "id": "reaction_10695694", "reactome": "R-PFA-4085331", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695681" ], "products": [ "species_10695689", "species_10694930" ], "modifiers": [ [ "species_10695691", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_0627500", "C6KTB1", "PF3D7_0627500", "Q8I444", "PF3D7_0505800", "PF3D7_0915100", "PF3D7_1360700" ] }, "reaction_10695645": { "compartment": "compartment_7660", "id": "reaction_10695645", "reactome": "R-PFA-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694938", "species_10695635" ], "products": [ "species_10695643", "species_10694930" ], "modifiers": [ [ "species_10694938", "catalyst" ] ], "additional_components": [ "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800", "PF3D7_1445900", "Q8I444", "PF3D7_0505800", "Q8IL13", "PF3D7_1445900", "PF3D7_0915100", "Q8I301", "PF3D7_0915100", "Q8I444", "PF3D7_0505800" ] }, "reaction_10690843": { "compartment": "compartment_70101", "id": "reaction_10690843", "reactome": "R-PFA-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690808", "species_70106", "species_29368", "species_73473" ], "products": [ "species_29356", "species_10690833", "species_29360" ], "modifiers": [ [ "species_10690840", "catalyst" ] ], "additional_components": [ "Q8I603", "PF3D7_1204300", "Q8I603", "PF3D7_1204300", "Q8I701", "PF3D7_1302600", "species_71067" ] }, "reaction_10690826": { "compartment": "compartment_70101", "id": "reaction_10690826", "reactome": "R-PFA-204647", "name": "DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690814", "species_204635", "species_29360" ], "products": [ "species_70106", "species_10690808", "species_204628", "species_73473" ], "modifiers": [ [ "species_10690821", "catalyst" ] ], "additional_components": [ "Q8I603", "PF3D7_1204300", "Q8I603", "PF3D7_1204300", "Q8ILW8", "PF3D7_1412600" ] }, "reaction_10696630": { "compartment": "compartment_70101", "id": "reaction_10696630", "reactome": "R-PFA-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696605", "species_71284" ], "products": [ "species_353106", "species_10696592" ], "modifiers": [ [ "species_10696622", "catalyst" ], [ "species_10696628", "catalyst" ] ], "additional_components": [ "PF3D7_1451100", "PF3D7_1451100", "Q8ILV7", "PF3D7_1413800", "Q8ILG9", "PF3D7_1429500", "Q8I5N0", "PF3D7_1217800", "PF3D7_0502800" ] }, "reaction_10696603": { "compartment": "compartment_70101", "id": "reaction_10696603", "reactome": "R-PFA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10696592" ], "products": [ "species_71285", "species_10696595" ], "modifiers": [ [ "species_10696600", "catalyst" ] ], "additional_components": [ "PF3D7_1451100", "PF3D7_1451100", "PF3D7_1009000" ] }, "reaction_10699358": { "compartment": "compartment_12045", "id": "reaction_10699358", "reactome": "R-PFA-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_71285", "species_6788758" ], "modifiers": [ [ "species_10699355", "catalyst" ] ], "additional_components": [ "Q8I555", "PF3D7_1236800", "species_216785" ] }, "reaction_10689522": { "compartment": "compartment_12045", "id": "reaction_10689522", "reactome": "R-PFA-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855663" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10689519", "catalyst" ] ], "additional_components": [ "PF3D7_1247300" ] }, "reaction_10689506": { "compartment": "compartment_12045", "id": "reaction_10689506", "reactome": "R-PFA-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855667" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10689503", "catalyst" ] ], "additional_components": [ "PF3D7_1341600" ] }, "reaction_10689514": { "compartment": "compartment_70101", "id": "reaction_10689514", "reactome": "R-PFA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_8855661", "species_29416" ], "modifiers": [ [ "species_10689511", "catalyst" ] ], "additional_components": [ "PF3D7_0624700" ] }, "reaction_10689498": { "compartment": "compartment_17957", "id": "reaction_10689498", "reactome": "R-PFA-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_8855666", "species_76194" ], "modifiers": [ [ "species_10689495", "catalyst" ] ], "additional_components": [ "PF3D7_0615300" ] }, "reaction_10692115": { "compartment": "compartment_12045", "id": "reaction_10692115", "reactome": "R-PFA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449222" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10692112", "catalyst" ] ], "additional_components": [ "Q8IAQ4", "PF3D7_0806400", "O96196", "PF3D7_0211600" ] }, "reaction_10692070": { "compartment": "compartment_12045", "id": "reaction_10692070", "reactome": "R-PFA-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449299" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10692067", "catalyst" ] ], "additional_components": [ "PF3D7_0321200" ] }, "reaction_10695754": { "compartment": "compartment_12045", "id": "reaction_10695754", "reactome": "R-PFA-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419981", "species_29364" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10695751", "catalyst" ] ], "additional_components": [ "PF3D7_1455900" ] }, "reaction_10692078": { "compartment": "compartment_12045", "id": "reaction_10692078", "reactome": "R-PFA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_449221" ], "products": [ "species_110094", "species_449299" ], "modifiers": [ [ "species_10692075", "catalyst" ] ], "additional_components": [ "PF3D7_0109850" ] }, "reaction_10699345": { "compartment": "compartment_70101", "id": "reaction_10699345", "reactome": "R-PFA-6787632", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860" ], "products": [ "species_29356", "species_6787618" ], "modifiers": [ [ "species_10699342", "catalyst" ] ], "additional_components": [ "PF3D7_0813800" ] }, "reaction_10699348": { "compartment": "compartment_70101", "id": "reaction_10699348", "reactome": "R-PFA-6787642", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6787646", "species_29364" ], "products": [ "species_742368", "species_29366" ], "modifiers": [ [ "species_10699334", "catalyst" ] ], "additional_components": [ "A0A143ZXB3", "PF3D7_1014000" ] }, "reaction_10699337": { "compartment": "compartment_70101", "id": "reaction_10699337", "reactome": "R-PFA-6787623", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787618" ], "products": [ "species_6787646" ], "modifiers": [ [ "species_10699334", "catalyst" ] ], "additional_components": [ "A0A143ZXB3", "PF3D7_1014000" ] }, "reaction_10692100": { "compartment": "compartment_70101", "id": "reaction_10692100", "reactome": "R-PFA-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_532204" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10692097", "catalyst" ] ], "additional_components": [ "Q8IDQ3", "PF3D7_1343600" ] }, "reaction_10692127": { "compartment": "compartment_70101", "id": "reaction_10692127", "reactome": "R-PFA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512", "species_29472" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10692124", "catalyst" ] ], "additional_components": [ "Q8IJF3", "PF3D7_1025100" ] }, "reaction_10692062": { "compartment": "compartment_70101", "id": "reaction_10692062", "reactome": "R-PFA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10692059", "catalyst" ] ], "additional_components": [ "PF3D7_1130000" ] }, "reaction_10701400": { "compartment": "compartment_20699", "id": "reaction_10701400", "reactome": "R-PFA-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698591", "species_10698587", "species_10701396" ], "products": [ "species_10701398" ], "modifiers": [], "additional_components": [ "Q8I0X0", "PF3D7_0509000", "O77313", "PF3D7_0303000", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IKE6", "PF3D7_1469100", "C0H5D3", "PF3D7_1324700", "Q8IE08", "PF3D7_1332000", "Q8IIP9", "PF3D7_1111300", "Q8IKE6", "PF3D7_1469100", "C0H5D3", "PF3D7_1324700", "O77313", "PF3D7_0303000", "Q8I0X0", "PF3D7_0509000" ] }, "reaction_10701278": { "compartment": "compartment_6791047", "id": "reaction_10701278", "reactome": "R-PFA-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701225", "species_10701274" ], "products": [ "species_10701276" ], "modifiers": [], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8II16", "PF3D7_1134800", "Q8IHR6", "PF3D7_1145100", "Q8ILG6", "PF3D7_1429800", "Q8I1T3", "PF3D7_0415400", "Q8I390", "PF3D7_0905900", "C0H4T1", "PF3D7_0808400", "C6KSR5", "PF3D7_0606700", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203" ] }, "reaction_10701228": { "compartment": "compartment_6791047", "id": "reaction_10701228", "reactome": "R-PFA-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10701223" ], "products": [ "species_29370", "species_10701225" ], "modifiers": [ [ "species_10701223", "catalyst" ] ], "additional_components": [ "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "Q8I3W9", "PF3D7_0513800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "Q8IL42", "PF3D7_1442900", "Q7KQL3", "PF10_0203", "species_29420" ] }, "reaction_10692738": { "compartment": "compartment_17963", "id": "reaction_10692738", "reactome": "R-PFA-914017", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10692672" ], "products": [ "species_205687", "species_10692736" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10692704": { "compartment": "compartment_17963", "id": "reaction_10692704", "reactome": "R-PFA-914008", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10692672" ], "products": [ "species_10692702", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10692694": { "compartment": "compartment_17963", "id": "reaction_10692694", "reactome": "R-PFA-914006", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10692672" ], "products": [ "species_10692692", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500" ] }, "reaction_10692684": { "compartment": "compartment_17963", "id": "reaction_10692684", "reactome": "R-PFA-914005", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10692672" ], "products": [ "species_10692682", "species_205687" ], "modifiers": [], "additional_components": [ "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900", "Q8IKY8", "PF3D7_1448500", "A0A143ZYL5", "PF3D7_1036900" ] }, "reaction_10696147": { "compartment": "compartment_12045", "id": "reaction_10696147", "reactome": "R-PFA-5173192", "name": "POFUT2 transfers fucose to TSR domain-containing proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696139" ], "products": [ "species_10696118" ], "modifiers": [ [ "species_10696144", "catalyst" ] ], "additional_components": [ "O97267", "PF3D7_0315200", "O97267", "PF3D7_0315200", "PF3D7_0909200" ] }, "reaction_10698145": { "compartment": "compartment_70101", "id": "reaction_10698145", "reactome": "R-PFA-5690159", "name": "USP21 deubiquitinates RIPK1,DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698138" ], "products": [ "species_10698142", "species_10698072" ], "modifiers": [ [ "species_10698138", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8IDK6", "PF3D7_1349300", "Q8IL78", "PF3D7_1439100", "Q8ILU9", "PF3D7_1414700", "Q8IL78", "PF3D7_1439100", "Q8IDK6", "PF3D7_1349300", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8ILU9", "PF3D7_1414700", "Q8IDK6", "PF3D7_1349300", "Q8IL78", "PF3D7_1439100" ] }, "reaction_10698720": { "compartment": "compartment_7660", "id": "reaction_10698720", "reactome": "R-PFA-5696960", "name": "USP49 deubiquitinates H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698715" ], "products": [ "species_10698717", "species_10686649" ], "modifiers": [ [ "species_10698715", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8ILU9", "PF3D7_1414700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ILU9", "PF3D7_1414700" ] }, "reaction_10698089": { "compartment": "compartment_70101", "id": "reaction_10698089", "reactome": "R-PFA-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698085", "species_10697200" ], "products": [ "species_10698087" ], "modifiers": [], "additional_components": [ "PF3D7_0527200", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500", "Q8ILV5", "PF3D7_1414000", "Q8I3J3", "PF3D7_0527200" ] }, "reaction_10698681": { "compartment": "compartment_70101", "id": "reaction_10698681", "reactome": "R-PFA-5696627", "name": "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10698678" ], "products": [ "species_10689710", "species_10689705" ], "modifiers": [ [ "species_10698678", "catalyst" ] ], "additional_components": [ "Q8IDK6", "PF3D7_1349300", "O97313", "PFC1020c", "PF3D7_1349300", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8IDK6", "PF3D7_1349300", "O97313", "PFC1020c" ] }, "reaction_10698126": { "compartment": "compartment_7660", "id": "reaction_10698126", "reactome": "R-PFA-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698121" ], "products": [ "species_10686649", "species_10698123" ], "modifiers": [ [ "species_10698121", "catalyst" ] ], "additional_components": [ "Q8ILU9", "PF3D7_1414700", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ILU9", "PF3D7_1414700", "Q8ILU9", "PF3D7_1414700" ] }, "reaction_10699197": { "compartment": "compartment_7660", "id": "reaction_10699197", "reactome": "R-PFA-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10698740" ], "products": [ "species_10698744", "species_10699194" ], "modifiers": [ [ "species_10698740", "catalyst" ] ], "additional_components": [ "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700", "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I4U5", "PF3D7_1248900", "Q8IIU3", "PF3D7_1106000", "Q8IC23", "PF3D7_0704700" ] }, "reaction_10698352": { "compartment": "compartment_70101", "id": "reaction_10698352", "reactome": "R-PFA-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689705" ], "products": [ "species_10689703" ], "modifiers": [ [ "species_10686745", "catalyst" ] ], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "PF3D7_1368100" ] }, "reaction_10699265": { "compartment": "compartment_7660", "id": "reaction_10699265", "reactome": "R-PFA-6783238", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699261", "species_10699259" ], "products": [ "species_10699263" ], "modifiers": [], "additional_components": [ "PF3D7_1203900", "Q8ILN4", "PF3D7_1421600", "Q8ILN4", "PF3D7_1421600", "Q8I607", "PF3D7_1203900" ] }, "reaction_10702033": { "compartment": "compartment_70101", "id": "reaction_10702033", "reactome": "R-PFA-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701967", "species_113592", "species_10686740" ], "products": [ "species_111294", "species_10701969" ], "modifiers": [ [ "species_10701967", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702039": { "compartment": "compartment_70101", "id": "reaction_10702039", "reactome": "R-PFA-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693374", "species_113592", "species_10686740" ], "products": [ "species_111294", "species_10701971" ], "modifiers": [ [ "species_10693374", "catalyst" ] ], "additional_components": [ "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "PF3D7_1333200" ] }, "reaction_10701991": { "compartment": "compartment_70101", "id": "reaction_10701991", "reactome": "R-PFA-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701965", "species_10701969" ], "products": [ "species_10701989", "species_10701971" ], "modifiers": [], "additional_components": [ "Q8I2U3", "PF3D7_0921000.1", "Q8IJ70", "PF3D7_1033900", "Q8IDD9", "PF3D7_1356300", "Q8I607", "PF3D7_1203900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8I2U3", "PF3D7_0921000.1", "Q8IDD9", "PF3D7_1356300", "Q8I607", "PF3D7_1203900", "Q8IJ70", "PF3D7_1033900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10701895": { "compartment": "compartment_70101", "id": "reaction_10701895", "reactome": "R-PFA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701881", "species_10701879" ], "products": [ "species_10701883", "species_10701893" ], "modifiers": [], "additional_components": [ "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8IDZ6", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IDZ6", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10702070": { "compartment": "compartment_70101", "id": "reaction_10702070", "reactome": "R-PFA-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10686680" ], "products": [ "species_10686680", "species_10687728" ], "modifiers": [ [ "species_10698177", "catalyst" ] ], "additional_components": [ "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1460400" ] }, "reaction_10702036": { "compartment": "compartment_70101", "id": "reaction_10702036", "reactome": "R-PFA-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701971" ], "products": [ "species_10701967", "species_76577" ], "modifiers": [ [ "species_10701971", "catalyst" ] ], "additional_components": [ "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10701963": { "compartment": "compartment_7660", "id": "reaction_10701963", "reactome": "R-PFA-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686649", "species_10701897" ], "products": [ "species_10701961", "species_113541" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702074": { "compartment": "compartment_70101", "id": "reaction_10702074", "reactome": "R-PFA-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702072" ], "products": [ "species_10686680", "species_10688129" ], "modifiers": [ [ "species_10698177", "catalyst" ] ], "additional_components": [ "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1402500", "PF3D7_1460400" ] }, "reaction_10702041": { "compartment": "compartment_7660", "id": "reaction_10702041", "reactome": "R-PFA-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701961" ], "products": [ "species_164121", "species_10701993" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500" ] }, "reaction_10702030": { "compartment": "compartment_7660", "id": "reaction_10702030", "reactome": "R-PFA-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10686649", "species_10701993" ], "products": [ "species_10701995", "species_113541" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200" ] }, "reaction_10702028": { "compartment": "compartment_7660", "id": "reaction_10702028", "reactome": "R-PFA-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701995", "species_10702007" ], "products": [ "species_10701961", "species_10702026" ], "modifiers": [], "additional_components": [ "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "O77397", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8ILW5", "PF3D7_1412900.1", "Q8I2U3", "PF3D7_0921000.1", "Q8I607", "PF3D7_1203900", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8I5F9", "PF3D7_1333200", "Q8ID50", "PF3D7_1365900", "Q7KQK2", "PF3D7_1402500", "Q8IM64", "PF3D7_1402500", "Q8I607", "PF3D7_1203900", "O77397", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8ILW5", "PF3D7_1412900.1", "Q8I2U3", "PF3D7_0921000.1" ] }, "reaction_10702374": { "compartment": "compartment_70101", "id": "reaction_10702374", "reactome": "R-PFA-8865774", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_10691147" ], "products": [ "species_29372", "species_10702344", "species_29370" ], "modifiers": [ [ "species_10702371", "catalyst" ] ], "additional_components": [ "species_29420", "species_29438", "species_29438", "species_29420", "Q8IJU8", "PF3D7_1147200", "Q8IHP8", "PF3D7_1147200" ] }, "reaction_10688265": { "compartment": "compartment_70101", "id": "reaction_10688265", "reactome": "R-PFA-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111628", "species_70106" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10688271": { "compartment": "compartment_70101", "id": "reaction_10688271", "reactome": "R-PFA-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111627", "species_113592", "species_29472" ], "products": [ "species_111647", "species_29372", "species_29404", "species_29370" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10688255": { "compartment": "compartment_70101", "id": "reaction_10688255", "reactome": "R-PFA-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_76630" ], "products": [ "species_76632", "species_76633" ], "modifiers": [ [ "species_10688252", "catalyst" ] ], "additional_components": [ "species_73524", "Q08210", "PFF0160c" ] }, "reaction_10688268": { "compartment": "compartment_70101", "id": "reaction_10688268", "reactome": "R-PFA-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111647", "species_29448" ], "products": [ "species_111628", "species_29372" ], "modifiers": [ [ "species_10688262", "catalyst" ] ], "additional_components": [ "Q8IEN3", "PF3D7_1308200" ] }, "reaction_10702131": { "compartment": "compartment_17938", "id": "reaction_10702131", "reactome": "R-PFA-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702126", "species_29356" ], "products": [ "species_29372", "species_10702128" ], "modifiers": [ [ "species_10702126", "catalyst" ] ], "additional_components": [ "species_29438", "C0H516", "PF3D7_0903200", "species_29420", "C0H516", "PF3D7_0903200", "species_29438", "C0H516", "PF3D7_0903200" ] }, "reaction_10702146": { "compartment": "compartment_5683628", "id": "reaction_10702146", "reactome": "R-PFA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10702141", "species_29356" ], "products": [ "species_29372", "species_10702143" ], "modifiers": [ [ "species_10702141", "catalyst" ] ], "additional_components": [ "Q8IDL8", "PF3D7_1348100", "species_29438", "Q8IDL8", "PF3D7_1348100", "species_29420", "Q8IDL8", "PF3D7_1348100", "species_29438" ] }, "reaction_10702113": { "compartment": "compartment_17938", "id": "reaction_10702113", "reactome": "R-PFA-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10702102" ], "products": [ "species_29372", "species_10702104" ], "modifiers": [ [ "species_10702102", "catalyst" ], [ "species_10702111", "catalyst" ] ], "additional_components": [ "species_29438", "C0H516", "PF3D7_0903200", "C0H516", "PF3D7_0903200", "species_29420", "species_29438", "C0H516", "PF3D7_0903200", "Q8I379", "PF3D7_1114200", "Q8IIL9", "PF3D7_1114200" ] }, "reaction_10702850": { "compartment": "compartment_17938", "id": "reaction_10702850", "reactome": "R-PFA-8877451", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702823" ], "products": [ "species_10702685", "species_10702831", "species_29420" ], "modifiers": [ [ "species_10702847", "catalyst" ] ], "additional_components": [ "C0H516", "PF3D7_0903200", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "C0H516", "PF3D7_0903200", "species_29438", "Q8IIT1", "PF3D7_1107200", "Q8IDH2", "PF3D7_1352800" ] }, "reaction_10702761": { "compartment": "compartment_171062", "id": "reaction_10702761", "reactome": "R-PFA-8875320", "name": "RAB5 GEFs exchange GTP for GDP on RAB5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702687" ], "products": [ "species_10702685", "species_29420", "species_10702705" ], "modifiers": [ [ "species_10702758", "catalyst" ] ], "additional_components": [ "O96193", "PF3D7_0211200", "Q8I274", "PF3D7_0211200", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "Q8I274", "PF3D7_0211200", "O96193", "PF3D7_0211200", "species_29438", "Q8ILY5", "PF3D7_1411000.2", "A0A144A1B7", "PF3D7_1411000.2", "Q8IAZ5", "PF3D7_1411000.2" ] }, "reaction_10702910": { "compartment": "compartment_13946", "id": "reaction_10702910", "reactome": "R-PFA-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10702872" ], "products": [ "species_10702685", "species_29420", "species_10702886" ], "modifiers": [ [ "species_10702907", "catalyst" ] ], "additional_components": [ "A0A5K1K8H7", "PF3D7_0513800", "species_29420", "Q8I501", "PF3D7_1242800", "Q8I501", "PF3D7_1242800", "A0A5K1K8H7", "PF3D7_0513800", "species_29438", "C6KT27", "PF3D7_0618700", "Q8IM42", "PF3D7_1405200", "O77358", "PF3D7_0310700", "Q7KQM2", "PF14_0358", "Q8IE05", "PF3D7_1332300", "Q8I1Q2", "PF3D7_0418500", "Q8IBQ3", "PF3D7_0719900", "Q8I560", "PF3D7_1236300", "Q8I481", "PF3D7_0501900", "Q8I451", "PF3D7_0505100" ] }, "reaction_10689388": { "compartment": "compartment_17906", "id": "reaction_10689388", "reactome": "R-PFA-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689386" ], "products": [ "species_10689380" ], "modifiers": [], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "Q8I6T6", "PF3D7_1404100" ] }, "reaction_10693609": { "compartment": "compartment_5460", "id": "reaction_10693609", "reactome": "R-PFA-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693598", "species_379721", "species_10693585" ], "products": [ "species_10693606", "species_379697", "species_10693600" ], "modifiers": [ [ "species_10693585", "catalyst" ], [ "species_10693598", "catalyst" ] ], "additional_components": [ "CHEBI:33738", "Q8I5R0", "PF3D7_1214600", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067", "Q8I5R0", "PF3D7_1214600", "CHEBI:33737", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "CHEBI:33739", "Q8IBI5", "PF3D7_0727200", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067", "CHEBI:33738", "Q8I5R0", "PF3D7_1214600" ] }, "reaction_10693614": { "compartment": "compartment_5460", "id": "reaction_10693614", "reactome": "R-PFA-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693612", "species_113531" ], "products": [ "species_10693585" ], "modifiers": [], "additional_components": [ "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "Q8IKT4", "PF3D7_1454500", "Q8IEK7", "PF3D7_1311000", "Q8IBI5", "PF3D7_0727200", "species_71067" ] }, "reaction_10693558": { "compartment": "compartment_70101", "id": "reaction_10693558", "reactome": "R-PFA-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_8942986", "species_983036" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10703040": { "compartment": "compartment_70101", "id": "reaction_10703040", "reactome": "R-PFA-8940641", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032" ], "products": [ "species_8955634" ], "modifiers": [ [ "species_10703037", "catalyst" ] ], "additional_components": [ "PF3D7_1005700" ] }, "reaction_10693397": { "compartment": "compartment_70101", "id": "reaction_10693397", "reactome": "R-PFA-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693343", "species_10693394" ], "products": [ "species_10693392", "species_10693345" ], "modifiers": [ [ "species_10693343", "catalyst" ] ], "additional_components": [ "Q8IAW2", "PF3D7_0812600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600" ] }, "reaction_10693403": { "compartment": "compartment_70101", "id": "reaction_10693403", "reactome": "R-PFA-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693351", "species_10693345" ], "products": [ "species_111294", "species_10693343", "species_10693368", "species_76577" ], "modifiers": [ [ "species_10693351", "catalyst" ] ], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10693354": { "compartment": "compartment_70101", "id": "reaction_10693354", "reactome": "R-PFA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10693347" ], "products": [ "species_111294", "species_10693343", "species_10693351", "species_76577" ], "modifiers": [ [ "species_10693271", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693370": { "compartment": "compartment_70101", "id": "reaction_10693370", "reactome": "R-PFA-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10693368" ], "products": [ "species_983123", "species_10693271" ], "modifiers": [], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693400": { "compartment": "compartment_70101", "id": "reaction_10693400", "reactome": "R-PFA-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10686740", "species_29926", "species_10693392" ], "products": [ "species_111294", "species_29926", "species_10693394", "species_76577" ], "modifiers": [ [ "species_10693392", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900" ] }, "reaction_10693405": { "compartment": "compartment_70101", "id": "reaction_10693405", "reactome": "R-PFA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983035", "species_10693271", "species_10693345" ], "products": [ "species_10693347" ], "modifiers": [], "additional_components": [ "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8IAW2", "PF3D7_0812600", "Q8I1Q1", "PF3D7_0418600", "Q8ID38", "PF3D7_1367000", "Q8IJR4", "PF3D7_1410300", "Q8ILZ2", "PF3D7_1410300", "A0A144A1E5", "PF3D7_1247000.2", "A0A144A0T0", "PF3D7_1247000.2", "A0A5K1K8W0", "PF3D7_1363400", "Q8IC23", "PF3D7_0704700", "C6KTE0", "PF3D7_0630500", "Q8IAU5", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IB94", "PF3D7_0826100", "Q8I3G9", "PF3D7_0529900", "A0A144A3J8", "PF3D7_1468400", "Q8I1S9", "PF3D7_1123300", "Q8IID0", "PF3D7_1123300", "C0H4K6", "PF3D7_0704600" ] }, "reaction_10693372": { "compartment": "compartment_70101", "id": "reaction_10693372", "reactome": "R-PFA-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_10686740", "species_983032", "species_8942986", "species_983036" ], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10693366": { "compartment": "compartment_17957", "id": "reaction_10693366", "reactome": "R-PFA-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_983032" ], "products": [ "species_29372", "species_29370", "species_983034" ], "modifiers": [ [ "species_10693363", "catalyst" ] ], "additional_components": [ "Q8IHR3", "PF3D7_1145500" ] }, "reaction_10690798": { "compartment": "compartment_12045", "id": "reaction_10690798", "reactome": "R-PFA-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690794", "species_10690709" ], "products": [ "species_10690796" ], "modifiers": [], "additional_components": [ "Q8IB60", "PF3D7_0822600", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8I1S0", "PF3D7_0416800", "species_29438", "Q8I1S0", "PF3D7_0416800", "species_29438", "C0H489", "PF3D7_0405100", "C0H5J6", "PF3D7_1361100", "Q8IB60", "PF3D7_0822600" ] }, "reaction_10694518": { "compartment": "compartment_161320", "id": "reaction_10694518", "reactome": "R-PFA-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10694515", "catalyst" ] ], "additional_components": [ "Q8I6Z5", "PF3D7_1323500", "Q8IIL0", "PF3D7_1247800", "Q8I0V1", "PF3D7_1247800", "Q8I6U5", "PF3D7_1247800", "Q8I6U4", "PF3D7_1247800" ] }, "reaction_10698337": { "compartment": "compartment_7660", "id": "reaction_10698337", "reactome": "R-PFA-5691004", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698333", "species_10695924", "species_10695861" ], "products": [ "species_10698335" ], "modifiers": [], "additional_components": [ "Q8IJS8", "PF3D7_1011700", "PF3D7_1432600", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8ILD6", "PF3D7_1432600", "Q8IJS8", "PF3D7_1011700" ] }, "reaction_10688851": { "compartment": "compartment_7660", "id": "reaction_10688851", "reactome": "R-PFA-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688847", "species_10688842" ], "products": [ "species_10688849" ], "modifiers": [], "additional_components": [ "PF3D7_1368800", "PF3D7_0203300", "O96136", "PF3D7_0203300", "Q8ID22", "PF3D7_1368800" ] }, "reaction_10688768": { "compartment": "compartment_7660", "id": "reaction_10688768", "reactome": "R-PFA-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688760" ], "products": [ "species_10688765" ], "modifiers": [ [ "species_10688760", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578" ] }, "reaction_10688774": { "compartment": "compartment_7660", "id": "reaction_10688774", "reactome": "R-PFA-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687534", "species_10687529" ], "products": [ "species_10687536" ], "modifiers": [], "additional_components": [ "PF3D7_1369500", "PF3D7_0415500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500" ] }, "reaction_10688725": { "compartment": "compartment_7660", "id": "reaction_10688725", "reactome": "R-PFA-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688723" ], "products": [ "species_10688723" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688756": { "compartment": "compartment_7660", "id": "reaction_10688756", "reactome": "R-PFA-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688749" ], "products": [ "species_113550", "species_10688753" ], "modifiers": [ [ "species_10688749", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688772": { "compartment": "compartment_7660", "id": "reaction_10688772", "reactome": "R-PFA-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688765" ], "products": [ "species_10688770" ], "modifiers": [], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688763": { "compartment": "compartment_7660", "id": "reaction_10688763", "reactome": "R-PFA-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10688753" ], "products": [ "species_10688760", "species_111349" ], "modifiers": [ [ "species_10688753", "catalyst" ] ], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "species_113578", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688747": { "compartment": "compartment_7660", "id": "reaction_10688747", "reactome": "R-PFA-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688743", "species_10688737", "species_10688723" ], "products": [ "species_10688745" ], "modifiers": [], "additional_components": [ "PF3D7_0610900", "PF3D7_0705000", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10688776": { "compartment": "compartment_7660", "id": "reaction_10688776", "reactome": "R-PFA-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687606", "species_10687536" ], "products": [ "species_10687608" ], "modifiers": [], "additional_components": [ "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10688751": { "compartment": "compartment_7660", "id": "reaction_10688751", "reactome": "R-PFA-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688745", "species_72084", "species_29428" ], "products": [ "species_10688749" ], "modifiers": [], "additional_components": [ "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IC20", "PF3D7_0705000", "C6KSV4", "PF3D7_0610900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900" ] }, "reaction_10695347": { "compartment": "compartment_70101", "id": "reaction_10695347", "reactome": "R-PFA-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695322", "species_10695339", "species_10695331" ], "products": [ "species_10695318", "species_10695345" ], "modifiers": [], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "PF14_0324", "Q8IL88", "PF3D7_1437900", "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_113582", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10695362": { "compartment": "compartment_70101", "id": "reaction_10695362", "reactome": "R-PFA-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695358", "species_10695360" ], "products": [ "species_10695320" ], "modifiers": [], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10696814": { "compartment": "compartment_70101", "id": "reaction_10696814", "reactome": "R-PFA-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10695345" ], "products": [ "species_10696808" ], "modifiers": [], "additional_components": [ "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8ILC1", "PF14_0324", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_29358", "species_113582", "Q8IB24", "PF3D7_0818900" ] }, "reaction_10695325": { "compartment": "compartment_70101", "id": "reaction_10695325", "reactome": "R-PFA-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695320" ], "products": [ "species_29372", "species_10695322" ], "modifiers": [ [ "species_10695320", "catalyst" ], [ "species_10695318", "catalyst" ] ], "additional_components": [ "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_113582", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900", "species_29358", "Q8IB24", "PF3D7_0818900", "Q8IL88", "PF3D7_1437900" ] }, "reaction_10703669": { "compartment": "compartment_70101", "id": "reaction_10703669", "reactome": "R-PFA-9712274", "name": "NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703008", "species_9714134" ], "products": [ "species_10703667" ], "modifiers": [], "additional_components": [ "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100", "Q8IDQ2", "PF3D7_1343700", "Q8IAU5", "PF3D7_0811000", "C6KTD3", "PF3D7_0811000", "O77367", "PF3D7_0319100" ] }, "reaction_10695268": { "compartment": "compartment_17957", "id": "reaction_10695268", "reactome": "R-PFA-3341296", "name": "GPX7,8 catalyze peroxidation of P4HB (PDI)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10695241", "species_3341383" ], "products": [ "species_113519", "species_10695252" ], "modifiers": [ [ "species_10695265", "catalyst" ] ], "additional_components": [ "Q8I2V9", "PF3D7_1472600", "Q8IKB2", "PF3D7_1472600", "C0H4Y6", "PF3D7_1472600", "Q8IKB2", "PF3D7_1472600", "Q8I2V9", "PF3D7_1472600", "C0H4Y6", "PF3D7_1472600", "Q8IIC3", "PF3D7_1124000", "Q8I5T2", "PF3D7_1212000" ] }, "reaction_10695227": { "compartment": "compartment_70616", "id": "reaction_10695227", "reactome": "R-PFA-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10689563" ], "products": [ "species_10689561", "species_189461" ], "modifiers": [], "additional_components": [ "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "CHEBI:38574", "Q8I6T6", "PF3D7_1404100", "Q8IM53", "PF3D7_1404100", "CHEBI:38573" ] }, "reaction_10698668": { "compartment": "compartment_5460", "id": "reaction_10698668", "reactome": "R-PFA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696199", "species_113521" ], "products": [ "species_5696194", "species_113573" ], "modifiers": [ [ "species_10698665", "catalyst" ] ], "additional_components": [ "PF3D7_0520600" ] }, "reaction_10690238": { "compartment": "compartment_70101", "id": "reaction_10690238", "reactome": "R-PFA-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10690235", "catalyst" ] ], "additional_components": [ "species_29926", "C0H556", "PF3D7_0924300" ] }, "reaction_10690256": { "compartment": "compartment_70101", "id": "reaction_10690256", "reactome": "R-PFA-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73524" ], "products": [ "species_111294", "species_29386" ], "modifiers": [ [ "species_10690253", "catalyst" ] ], "additional_components": [ "PF3D7_1015000" ] }, "reaction_10690266": { "compartment": "compartment_70101", "id": "reaction_10690266", "reactome": "R-PFA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10690263", "catalyst" ] ], "additional_components": [ "Q8IDB3", "PF3D7_1359100", "species_29926" ] }, "reaction_10690356": { "compartment": "compartment_876", "id": "reaction_10690356", "reactome": "R-PFA-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10690353", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10690379": { "compartment": "compartment_70101", "id": "reaction_10690379", "reactome": "R-PFA-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690365", "species_1497805" ], "products": [ "species_10690363", "species_198816" ], "modifiers": [ [ "species_10690365", "catalyst" ] ], "additional_components": [ "species_917877", "Q8I599", "PF3D7_1232300", "CHEBI:36144", "Q8I599", "PF3D7_1232300", "species_917877", "Q8I599", "PF3D7_1232300" ] }, "reaction_10690376": { "compartment": "compartment_70101", "id": "reaction_10690376", "reactome": "R-PFA-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10690363", "species_73473" ], "products": [ "species_10690365", "species_29360" ], "modifiers": [ [ "species_10690373", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "Q8I599", "PF3D7_1232300", "species_917877", "Q8I599", "PF3D7_1232300", "Q8ID33", "PF3D7_1367500", "species_29386" ] }, "reaction_10694965": { "compartment": "compartment_70101", "id": "reaction_10694965", "reactome": "R-PFA-3000238", "name": "LMBRD1 transports lysosomal Cbl to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3000239" ], "products": [ "species_3000241" ], "modifiers": [ [ "species_10694962", "catalyst" ] ], "additional_components": [ "PF3D7_1338000" ] }, "reaction_10693012": { "compartment": "compartment_70101", "id": "reaction_10693012", "reactome": "R-PFA-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10692996" ], "products": [ "species_10693001", "species_29432" ], "modifiers": [ [ "species_10693009", "catalyst" ] ], "additional_components": [ "Q8ID54", "PF3D7_1365400", "species_216785", "species_216785", "Q8ID54", "PF3D7_1365400", "Q8IBI5", "PF3D7_0727200" ] }, "reaction_10690435": { "compartment": "compartment_70616", "id": "reaction_10690435", "reactome": "R-PFA-200720", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671" ], "products": [ "species_111355" ], "modifiers": [ [ "species_10690425", "catalyst" ] ], "additional_components": [ "PF3D7_0811100" ] }, "reaction_10700995": { "compartment": "compartment_70101", "id": "reaction_10700995", "reactome": "R-PFA-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_29372", "species_70106", "species_29370", "species_200640" ], "modifiers": [ [ "species_10700992", "catalyst" ] ], "additional_components": [ "PF3D7_1245000" ] }, "reaction_10690433": { "compartment": "compartment_70101", "id": "reaction_10690433", "reactome": "R-PFA-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690417": { "compartment": "compartment_70101", "id": "reaction_10690417", "reactome": "R-PFA-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10698693": { "compartment": "compartment_5460", "id": "reaction_10698693", "reactome": "R-PFA-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801451", "species_200671", "species_113593" ], "products": [ "species_113548", "species_113581", "species_5389850" ], "modifiers": [ [ "species_10698690", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690437": { "compartment": "compartment_70101", "id": "reaction_10690437", "reactome": "R-PFA-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_200640" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10700997": { "compartment": "compartment_5460", "id": "reaction_10700997", "reactome": "R-PFA-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_5389850" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10698690", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690420": { "compartment": "compartment_70101", "id": "reaction_10690420", "reactome": "R-PFA-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_29356", "species_200640" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10700987": { "compartment": "compartment_5460", "id": "reaction_10700987", "reactome": "R-PFA-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_5693984" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10700984", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10701000": { "compartment": "compartment_5460", "id": "reaction_10701000", "reactome": "R-PFA-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10700984", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10690431": { "compartment": "compartment_70101", "id": "reaction_10690431", "reactome": "R-PFA-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29372", "species_29370", "species_111353" ], "modifiers": [ [ "species_10690414", "catalyst" ] ], "additional_components": [ "C6KTE2", "PF3D7_0630700" ] }, "reaction_10693026": { "compartment": "compartment_70101", "id": "reaction_10693026", "reactome": "R-PFA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965053" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10693024": { "compartment": "compartment_70101", "id": "reaction_10693024", "reactome": "R-PFA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10693028": { "compartment": "compartment_70101", "id": "reaction_10693028", "reactome": "R-PFA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965131" ], "products": [ "species_29390", "species_29370" ], "modifiers": [ [ "species_10693021", "catalyst" ] ], "additional_components": [ "species_216785", "C6KT01", "PF3D7_0616000" ] }, "reaction_10688410": { "compartment": "compartment_70101", "id": "reaction_10688410", "reactome": "R-PFA-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83962", "species_500244" ], "products": [ "species_29372", "species_500430" ], "modifiers": [ [ "species_10688407", "catalyst" ] ], "additional_components": [ "CHEBI:28542", "species_112016", "CHEBI:16450", "CHEBI:16704", "Q8I3X4", "PF3D7_0513300" ] }, "reaction_10694172": { "compartment": "compartment_70101", "id": "reaction_10694172", "reactome": "R-PFA-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10694168", "species_10694166" ], "products": [ "species_10694170" ], "modifiers": [], "additional_components": [ "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200", "Q8IKX4", "PF3D7_1450100", "C6KT56", "PF3D7_0621900", "Q8I613", "PF3D7_1203200", "Q8II00", "PF3D7_1136400", "Q8I5P4", "PF3D7_1216300", "C0H4Q0", "PF3D7_0729000", "Q8IKX4", "PF3D7_1450100", "C6KT56", "PF3D7_0621900", "Q8I613", "PF3D7_1203200", "Q8II00", "PF3D7_1136400", "Q8I5P4", "PF3D7_1216300", "C0H4Q0", "PF3D7_0729000", "O97249", "PF3D7_0307100", "Q8I3R6", "PF3D7_0519400", "Q8IJD4", "PF10_0264", "Q8IEN2", "PF3D7_1308300", "Q8ILN8", "PF3D7_1421200", "Q8IDB0", "PF3D7_1358800", "O96258", "PF3D7_0217800", "A0A5K1K925", "PF3D7_0516200", "C0H5C2", "PF3D7_1317800", "Q7KQK2", "PF3D7_1402500", "Q8IAX5", "PF3D7_0813900", "Q8IKL9", "PF3D7_1461300", "Q8IIU8", "PF3D7_1105400", "C0H4K8", "PF3D7_0705700", "Q8IKH8", "PF3D7_1465900", "Q8I502", "PF3D7_1242700", "Q8IIA2", "PF3D7_1126200", "Q8IFP2", "PF3D7_0422400", "O97313", "PFC1020c", "O77395", "PF3D7_0316800", "Q8IBN5", "PF3D7_0721600", "Q8IL02", "PF3D7_1447000", "Q8IDR9", "PF3D7_1342000", "Q8IK02", "PF3D7_1003500", "Q8IET7", "PF3D7_1302800", "Q8IHS5", "PF3D7_1144000", "Q8IM10", "PF3D7_1408600", "Q8IBQ5", "PF3D7_0719700", "O97248", "PF3D7_0306900", "Q8I3R0", "PF3D7_0520000", "O77381", "PF3D7_0317600", "Q8I3B0", "PF3D7_0903900", "Q8I463", "PF3D7_0503800", "C0H4H3", "PF3D7_0611700", "Q8IJK8", "PF3D7_1019400", "C6S3J6", "PF3D7_1460300", "O97231", "PF3D7_0304400.1", "Q8IHU0", "PF3D7_1142500", "C6KT23", "PF3D7_0618300", "Q8IJC6", "PF3D7_1027800", "Q8I3T8", "PF3D7_0517000", "Q8I431", "PF3D7_0507100", "Q8IBQ6", "PF3D7_0719600", "Q8II62", "PF3D7_1130100", "Q8IL58", "PF3D7_1441200", "C0H4L5", "PF3D7_0706400", "Q8I713", "PF3D7_1109900", "O00806", "PF3D7_0309600", "Q8IHT9", "PF3D7_1142600", "Q8IIX0", "PF3D7_1103100", "Q8IIB4", "PF3D7_1124900", "Q8II61", "PF3D7_1130200", "Q8I3T9", "PF3D7_0516900", "C0H5G3", "PF3D7_1341300", "Q8ILL2", "PF3D7_1424400", "Q8IDI5", "PF3D7_1351400", "O97250", "PF3D7_0307200", "C0H4A6", "PF3D7_0415900", "A0A5K1K8V8", "PF3D7_1338200", "Q8ILE8", "PF3D7_1431700", "Q8ILL3", "PF3D7_1424100", "Q8IJZ7", "PF3D7_1004000", "Q8IAX6", "PF3D7_0814000", "Q8IKM5", "PF3D7_1460700", "O77364", "PF3D7_0312800", "Q8IEM3", "PF3D7_1309100", "Q8IB51", "PF3D7_0821700", "Q8IE82", "PF3D7_1323400", "Q8IE09", "PF3D7_1331800", "Q8ILV2", "PF3D7_1414300", "Q8ILK3", "PF3D7_1426000", "C6KSY6", "PF3D7_0614500", "Q8IE85", "PF3D7_1323100", "Q8IDS6", "PF3D7_1341200" ] }, "reaction_10696497": { "compartment": "compartment_70101", "id": "reaction_10696497", "reactome": "R-PFA-5263614", "name": "MeSeOH is reduced to MeSeH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357663", "species_70106", "species_29364" ], "products": [ "species_29356", "species_29366", "species_5357669" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "P61076", "PFI1170c", "species_29386" ] }, "reaction_10696500": { "compartment": "compartment_70101", "id": "reaction_10696500", "reactome": "R-PFA-5263616", "name": "MeSeO2H is reduced to MeSeOH by TXNRD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5357694", "species_70106", "species_29364" ], "products": [ "species_5357663", "species_29356", "species_29366" ], "modifiers": [ [ "species_10688327", "catalyst" ] ], "additional_components": [ "P61076", "PFI1170c", "species_29386" ] }, "reaction_10696797": { "compartment": "compartment_5263232", "id": "reaction_10696797", "reactome": "R-PFA-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696793", "species_30389" ], "products": [ "species_10696795", "species_10696785" ], "modifiers": [], "additional_components": [ "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800", "Q7KQK0", "PF3D7_1223100", "Q7KQK0", "PF3D7_1223100", "species_30389", "C0H4P1", "PF3D7_0934800", "Q8I719", "PF3D7_1436600", "Q7K6A0", "PF3D7_0934800" ] }, "reaction_10687497": { "compartment": "compartment_70101", "id": "reaction_10687497", "reactome": "R-PFA-71732", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10687494", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "O77392", "PF3D7_0316300.2", "C0H477", "PF3D7_0316300.2" ] }, "reaction_10692143": { "compartment": "compartment_5460", "id": "reaction_10692143", "reactome": "R-PFA-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159450", "species_113521" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10692140", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "C0H477", "PF3D7_0316300.2", "O77392", "PF3D7_0316300.2" ] }, "reaction_10696800": { "compartment": "compartment_70101", "id": "reaction_10696800", "reactome": "R-PFA-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10690143", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10696902": { "compartment": "compartment_70616", "id": "reaction_10696902", "reactome": "R-PFA-5623643", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623644", "species_5623648", "species_163953" ], "products": [ "species_5623650", "species_5623649" ], "modifiers": [ [ "species_10696899", "catalyst" ] ], "additional_components": [ "PF3D7_0626100" ] }, "reaction_10690305": { "compartment": "compartment_7660", "id": "reaction_10690305", "reactome": "R-PFA-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690301" ], "products": [ "species_10690303" ], "modifiers": [], "additional_components": [ "PF3D7_1113900", "PF3D7_1113900" ] }, "reaction_10701024": { "compartment": "compartment_70101", "id": "reaction_10701024", "reactome": "R-PFA-6803890", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701020" ], "products": [ "species_10701022" ], "modifiers": [], "additional_components": [ "C0H4V6", "PF3D7_1362100", "A0A5K1K948", "PF3D7_1362100", "C0H4V6", "PF3D7_1362100", "A0A5K1K948", "PF3D7_1362100" ] }, "reaction_10689362": { "compartment": "compartment_7660", "id": "reaction_10689362", "reactome": "R-PFA-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689307", "species_10689316" ], "products": [ "species_10689318" ], "modifiers": [], "additional_components": [ "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000" ] }, "reaction_10689339": { "compartment": "compartment_7660", "id": "reaction_10689339", "reactome": "R-PFA-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687608", "species_10688666", "species_10689314" ], "products": [ "species_10688666", "species_10689316" ], "modifiers": [ [ "species_10689314", "catalyst" ] ], "additional_components": [ "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "PF3D7_1012700", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "PF3D7_1012700" ] }, "reaction_10694275": { "compartment": "compartment_7660", "id": "reaction_10694275", "reactome": "R-PFA-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694195": { "compartment": "compartment_7660", "id": "reaction_10694195", "reactome": "R-PFA-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694341": { "compartment": "compartment_7660", "id": "reaction_10694341", "reactome": "R-PFA-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023922" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694335": { "compartment": "compartment_7660", "id": "reaction_10694335", "reactome": "R-PFA-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023940" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694254": { "compartment": "compartment_7660", "id": "reaction_10694254", "reactome": "R-PFA-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10694192", "catalyst" ] ], "additional_components": [ "Q8I3W0", "PF3D7_1316100", "Q8IEF3", "PF3D7_1316100" ] }, "reaction_10694213": { "compartment": "compartment_70101", "id": "reaction_10694213", "reactome": "R-PFA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10694210", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694251": { "compartment": "compartment_70101", "id": "reaction_10694251", "reactome": "R-PFA-1855178", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629756" ], "products": [ "species_1629731" ], "modifiers": [ [ "species_10694248", "catalyst" ] ], "additional_components": [ "species_113526", "Q8I3Y8", "PF3D7_0511800" ] }, "reaction_10694329": { "compartment": "compartment_876", "id": "reaction_10694329", "reactome": "R-PFA-1855222", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10694281", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694338": { "compartment": "compartment_70101", "id": "reaction_10694338", "reactome": "R-PFA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_1629765", "species_29370" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694208": { "compartment": "compartment_70101", "id": "reaction_10694208", "reactome": "R-PFA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694272": { "compartment": "compartment_70101", "id": "reaction_10694272", "reactome": "R-PFA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694298": { "compartment": "compartment_70101", "id": "reaction_10694298", "reactome": "R-PFA-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10694263", "catalyst" ] ], "additional_components": [ "Q8ILG1", "PF3D7_1430300" ] }, "reaction_10694266": { "compartment": "compartment_70101", "id": "reaction_10694266", "reactome": "R-PFA-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10694263", "catalyst" ] ], "additional_components": [ "Q8ILG1", "PF3D7_1430300" ] }, "reaction_10694269": { "compartment": "compartment_70101", "id": "reaction_10694269", "reactome": "R-PFA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694332": { "compartment": "compartment_70101", "id": "reaction_10694332", "reactome": "R-PFA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10694205", "catalyst" ] ], "additional_components": [ "Q8IEF3", "PF3D7_1316100", "Q8I3W0", "PF3D7_1316100" ] }, "reaction_10694241": { "compartment": "compartment_70101", "id": "reaction_10694241", "reactome": "R-PFA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10694238", "catalyst" ] ], "additional_components": [ "species_74016", "Q8IJR0", "PF3D7_1013500" ] }, "reaction_10694288": { "compartment": "compartment_876", "id": "reaction_10694288", "reactome": "R-PFA-1855213", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10694285", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10694295": { "compartment": "compartment_12045", "id": "reaction_10694295", "reactome": "R-PFA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10694292", "catalyst" ] ], "additional_components": [ "Q8IJR0", "PF3D7_1013500", "species_74016" ] }, "reaction_10694326": { "compartment": "compartment_876", "id": "reaction_10694326", "reactome": "R-PFA-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10694323", "catalyst" ] ], "additional_components": [ "species_74016", "Q8IJR0", "PF3D7_1013500" ] }, "reaction_10694301": { "compartment": "compartment_70101", "id": "reaction_10694301", "reactome": "R-PFA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10694210", "catalyst" ] ], "additional_components": [ "Q8IC15", "PF3D7_0705500", "A0A143ZZC6", "PF3D7_1111600" ] }, "reaction_10701576": { "compartment": "compartment_70101", "id": "reaction_10701576", "reactome": "R-PFA-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701570" ], "products": [ "species_29372", "species_10701574" ], "modifiers": [], "additional_components": [ "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "species_29358", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "Q8I5C4", "PF3D7_1229500", "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "species_113582", "Q8I5C4", "PF3D7_1229500" ] }, "reaction_10701580": { "compartment": "compartment_70101", "id": "reaction_10701580", "reactome": "R-PFA-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701578", "species_113592" ], "products": [ "species_29370", "species_10701570" ], "modifiers": [], "additional_components": [ "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "species_113582", "Q8I5C4", "PF3D7_1229500", "O96220", "PF3D7_0214000", "C0H5I7", "PF3D7_1357800", "O97282", "PF3D7_0320300", "O97247", "PF3D7_0306800", "O77323", "PFC0350c", "species_29358", "C6KST5", "PF3D7_0608700", "Q8II43", "PF3D7_1132200", "Q8I5C4", "PF3D7_1229500" ] }, "reaction_10701763": { "compartment": "compartment_17963", "id": "reaction_10701763", "reactome": "R-PFA-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_8851233" ], "products": [ "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10701757", "catalyst" ] ], "additional_components": [ "species_110577", "species_29494", "species_29438", "species_30187", "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701760": { "compartment": "compartment_17963", "id": "reaction_10701760", "reactome": "R-PFA-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851226", "species_8851227" ], "modifiers": [ [ "species_10701757", "catalyst" ] ], "additional_components": [ "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_113578", "species_109366", "species_109402", "species_109395", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701792": { "compartment": "compartment_984", "id": "reaction_10701792", "reactome": "R-PFA-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701750": { "compartment": "compartment_984", "id": "reaction_10701750", "reactome": "R-PFA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701747", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701733": { "compartment": "compartment_984", "id": "reaction_10701733", "reactome": "R-PFA-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701730", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701780": { "compartment": "compartment_984", "id": "reaction_10701780", "reactome": "R-PFA-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8851462" ], "products": [ "species_109277", "species_8851461" ], "modifiers": [ [ "species_10701777", "catalyst" ] ], "additional_components": [ "CHEBI:17808", "species_205687", "species_29420", "species_110094", "species_109402", "species_29602", "species_109395", "species_113578", "species_29926", "species_74016", "Q8ILE7", "PF3D7_1431800" ] }, "reaction_10701787": { "compartment": "compartment_528865", "id": "reaction_10701787", "reactome": "R-PFA-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851517", "species_8851509" ], "products": [ "species_8851513", "species_8851518" ], "modifiers": [ [ "species_10701784", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110577", "species_110094", "species_205687", "species_29420", "Q8IE96", "PF3D7_1322000", "species_74016" ] }, "reaction_10701753": { "compartment": "compartment_984", "id": "reaction_10701753", "reactome": "R-PFA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701747", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701736": { "compartment": "compartment_876", "id": "reaction_10701736", "reactome": "R-PFA-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10701730", "catalyst" ] ], "additional_components": [ "Q8IE96", "PF3D7_1322000", "species_29926", "species_74016" ] }, "reaction_10701743": { "compartment": "compartment_984", "id": "reaction_10701743", "reactome": "R-PFA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936166", "species_109276" ], "products": [ "species_109277", "species_8851092" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_2509836", "species_29438", "species_29494", "species_110577", "species_29358", "CHEBI:17808", "species_113582", "species_205687", "species_29420", "species_110094", "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10701773": { "compartment": "compartment_984", "id": "reaction_10701773", "reactome": "R-PFA-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936165" ], "products": [ "species_8851369", "species_109277" ], "modifiers": [ [ "species_10701770", "catalyst" ] ], "additional_components": [ "species_113582", "species_205687", "species_29420", "species_110094", "species_109402", "species_109395", "species_113578", "species_76577", "species_29926", "species_74016", "Q8ILE7", "PF3D7_1431800" ] }, "reaction_10701789": { "compartment": "compartment_984", "id": "reaction_10701789", "reactome": "R-PFA-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10701740", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "Q8IE96", "PF3D7_1322000" ] }, "reaction_10696804": { "compartment": "compartment_876", "id": "reaction_10696804", "reactome": "R-PFA-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691235", "species_10691203" ], "products": [ "species_10696802" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "PF3D7_1348800", "A0A5K1K8L6", "PF3D7_1348800", "C0H553", "PF3D7_0923200" ] }, "reaction_10688530": { "compartment": "compartment_17940", "id": "reaction_10688530", "reactome": "R-PFA-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10688527", "catalyst" ] ], "additional_components": [ "C0H4P0", "PF3D7_0721900", "Q8I3R7", "PF3D7_0519200", "Q8IAQ8", "PF3D7_0806800", "Q8IDF7", "PF3D7_1354400", "Q8IKJ0", "PF3D7_1464700", "Q8I2H3", "PF3D7_0934500", "Q8IE84", "PF3D7_1323200", "Q76NM6", "PF13_0065", "Q8IHW4", "PF3D7_1140100", "Q8IEP9", "PF3D7_1306600", "Q8I280", "PF3D7_0106100", "Q6ZMA8", "PF3D7_0406100", "Q8IDS0", "PF3D7_1341900" ] }, "reaction_10692234": { "compartment": "compartment_70101", "id": "reaction_10692234", "reactome": "R-PFA-450466", "name": "AUF1:mRNA complex is destroyed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692232" ], "products": [], "modifiers": [ [ "species_10686934", "catalyst" ] ], "additional_components": [ "Q8I2Y5", "PF3D7_0916700", "O96153", "PF3D7_0205900", "Q8IK90", "PF3D7_1474800", "Q8I0U7", "PF3D7_0931800", "Q8IJA0", "PF3D7_1030500", "Q8ID28", "PF3D7_1368100", "Q8IJT1", "PF3D7_1011400", "Q8IJM0", "PF3D7_1017900", "Q7K6A9", "PF3D7_0803800", "Q8IDG2", "PF3D7_1353900", "Q8I261", "PF3D7_0108000", "Q8IJU4", "PF3D7_1010100", "Q8IM66", "PF3D7_1402300", "Q8IKH3", "PF3D7_1466300", "Q8IKC9", "PF3D7_1470900", "Q8I374", "PF3D7_0907700", "Q8I6T3", "PF3D7_1328100", "A0A5K1K7U1", "PF3D7_0518300", "Q8IEQ1", "PF3D7_1306400", "O77379", "PF3D7_0317800", "Q8I4U5", "PF3D7_1248900", "O77345", "PF3D7_0312300", "Q8I1V1", "PF3D7_0413600", "Q8I323", "PF3D7_0912900", "Q8II60", "PF3D7_1130400", "Q8IAR3", "PF3D7_0807500", "Q8IBI3", "PF3D7_0727400", "Q8IDG3", "PF3D7_1353800", "Q8II71", "PF3D7_1129200", "Q8IEK3", "PF3D7_1311500", "Q8IAR6", "PF3D7_0807800", "O77396", "PF3D7_0317000", "Q8IJW0", "PF3D7_1008400", "A0A5K1K9F3", "PF3D7_1338100", "C6KST3", "PF3D7_0608500" ] }, "reaction_10692221": { "compartment": "compartment_70101", "id": "reaction_10692221", "reactome": "R-PFA-450434", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450444", "species_10692215" ], "products": [ "species_10692219" ], "modifiers": [], "additional_components": [ "Q8I2Y5", "PF3D7_0916700", "Q8I2Y5", "PF3D7_0916700" ] }, "reaction_10701160": { "compartment": "compartment_7660", "id": "reaction_10701160", "reactome": "R-PFA-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10701156", "species_10689351" ], "products": [ "species_10701158" ], "modifiers": [], "additional_components": [ "Q8IDR5", "PF3D7_1342400", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400", "Q8IDR5", "PF3D7_1342400", "Q8IIR9", "PF3D7_1108400", "O77385", "PF3D7_0317200" ] }, "reaction_10700957": { "compartment": "compartment_876", "id": "reaction_10700957", "reactome": "R-PFA-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10700953", "species_10700948" ], "products": [ "species_10700955" ], "modifiers": [], "additional_components": [ "PF3D7_0602500", "PF3D7_1442500", "Q8IL46", "PF3D7_1442500", "C6KSM5", "PF3D7_0602500" ] }, "reaction_10701682": { "compartment": "compartment_70101", "id": "reaction_10701682", "reactome": "R-PFA-8848829", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692652", "species_10686740" ], "products": [ "species_10701679" ], "modifiers": [ [ "species_10692652", "catalyst" ] ], "additional_components": [ "PF3D7_1208800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "PF3D7_1208800", "PF3D7_1208800" ] }, "reaction_10694665": { "compartment": "compartment_70101", "id": "reaction_10694665", "reactome": "R-PFA-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690558", "species_179856" ], "products": [ "species_10694663" ], "modifiers": [], "additional_components": [ "PF3D7_1121900", "species_179856", "Q8IIE7", "PF3D7_1121900" ] }, "reaction_10692274": { "compartment": "compartment_5460", "id": "reaction_10692274", "reactome": "R-PFA-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374064", "species_113521" ], "products": [ "species_374061", "species_113585" ], "modifiers": [ [ "species_10692271", "catalyst" ] ], "additional_components": [ "species_1981162", "Q8I384", "PF3D7_0906500" ] }, "reaction_10687249": { "compartment": "compartment_70101", "id": "reaction_10687249", "reactome": "R-PFA-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29468" ], "products": [ "species_29514", "species_29498" ], "modifiers": [ [ "species_10687246", "catalyst" ] ], "additional_components": [ "species_1981162", "Q8I384", "PF3D7_0906500" ] }, "reaction_10690983": { "compartment": "compartment_70101", "id": "reaction_10690983", "reactome": "R-PFA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_204635", "species_353106" ], "modifiers": [ [ "species_10690980", "catalyst" ] ], "additional_components": [ "PF3D7_1129000" ] }, "reaction_10687304": { "compartment": "compartment_70101", "id": "reaction_10687304", "reactome": "R-PFA-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10687301", "catalyst" ] ], "additional_components": [ "PF3D7_1033100" ] }, "reaction_10690975": { "compartment": "compartment_70101", "id": "reaction_10690975", "reactome": "R-PFA-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_353555", "species_76194" ], "modifiers": [ [ "species_10690970", "catalyst" ] ], "additional_components": [ "PF3D7_0713900" ] }, "reaction_10690973": { "compartment": "compartment_70101", "id": "reaction_10690973", "reactome": "R-PFA-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10690970", "catalyst" ] ], "additional_components": [ "PF3D7_0713900" ] }, "reaction_10687283": { "compartment": "compartment_5460", "id": "reaction_10687283", "reactome": "R-PFA-70654", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113585" ], "products": [ "species_31339", "species_113552" ], "modifiers": [ [ "species_10687280", "catalyst" ] ], "additional_components": [ "Q6LFH8", "PFF0435w" ] }, "reaction_10699301": { "compartment": "compartment_70101", "id": "reaction_10699301", "reactome": "R-PFA-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_35305", "species_29364" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10699298", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10699294": { "compartment": "compartment_5460", "id": "reaction_10699294", "reactome": "R-PFA-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10699291", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10687293": { "compartment": "compartment_5460", "id": "reaction_10687293", "reactome": "R-PFA-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10687290", "catalyst" ] ], "additional_components": [ "Q8IDC6", "PF3D7_1357900" ] }, "reaction_10690407": { "compartment": "compartment_876", "id": "reaction_10690407", "reactome": "R-PFA-200396", "name": "Creatine transport across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200381", "species_74113" ], "products": [ "species_29916", "species_83910" ], "modifiers": [ [ "species_10690404", "catalyst" ] ], "additional_components": [ "O96181", "PF3D7_0209600" ] }, "reaction_10699868": { "compartment": "compartment_70101", "id": "reaction_10699868", "reactome": "R-PFA-6797956", "name": "SLC44A1 transports Cho from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618" ], "products": [ "species_6798162" ], "modifiers": [ [ "species_10699865", "catalyst" ] ], "additional_components": [ "PF3D7_1431900" ] }, "reaction_10687346": { "compartment": "compartment_5460", "id": "reaction_10687346", "reactome": "R-PFA-70844", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_70836" ], "products": [ "species_70843", "species_113559" ], "modifiers": [ [ "species_10687343", "catalyst" ] ], "additional_components": [ "Q8IKW7", "PF3D7_1450900" ] }, "reaction_10698395": { "compartment": "compartment_5460", "id": "reaction_10698395", "reactome": "R-PFA-5693153", "name": "PPM1K dephosphorylates p-BCKDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10698385", "species_113521" ], "products": [ "species_113548", "species_10687333" ], "modifiers": [ [ "species_10698392", "catalyst" ] ], "additional_components": [ "O97227", "PF3D7_0303700", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I0X1", "PF3D7_0504600", "Q8I5A0", "PF3D7_1232200", "species_29386", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I5A0", "PF3D7_1232200", "species_29386", "C0H4T6", "PF3D7_0810300", "species_1981162" ] }, "reaction_10687354": { "compartment": "compartment_5460", "id": "reaction_10687354", "reactome": "R-PFA-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10687351", "catalyst" ] ], "additional_components": [ "PF3D7_1240000" ] }, "reaction_10687336": { "compartment": "compartment_5460", "id": "reaction_10687336", "reactome": "R-PFA-70713", "name": "BCKDH transfers CoA group from CoA-SH to BCAAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_508181" ], "products": [ "species_29362", "species_508261", "species_29376" ], "modifiers": [ [ "species_10687333", "catalyst" ] ], "additional_components": [ "CHEBI:16530", "CHEBI:28654", "CHEBI:17865", "CHEBI:15479", "CHEBI:15487", "CHEBI:15477", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "species_29480", "Q8IEJ6", "PF3D7_1312600", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10699863": { "compartment": "compartment_5460", "id": "reaction_10699863", "reactome": "R-PFA-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699853", "species_6793610", "species_2162265" ], "products": [ "species_379705", "species_6793613", "species_10698401" ], "modifiers": [ [ "species_10699860", "catalyst" ] ], "additional_components": [ "PF3D7_1132900", "PF3D7_1132900", "Q8IDQ0", "MAL13P1.220", "CHEBI:49883" ] }, "reaction_10699850": { "compartment": "compartment_5460", "id": "reaction_10699850", "reactome": "R-PFA-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10699840", "species_10698401" ], "products": [ "species_10699842", "species_10698403" ], "modifiers": [ [ "species_10699847", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386", "Q8I0X1", "PF3D7_0504600", "Q8IEJ6", "PF3D7_1312600", "O97227", "PF3D7_0303700", "PF3D7_1132900", "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386", "O97227", "PF3D7_0303700", "Q8I0X1", "PF3D7_0504600", "Q8IEJ6", "PF3D7_1312600", "PF3D7_1132900", "PF3D7_1314600" ] }, "reaction_10699304": { "compartment": "compartment_5460", "id": "reaction_10699304", "reactome": "R-PFA-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784236", "species_113587" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10687257", "catalyst" ] ], "additional_components": [ "O96142", "PF3D7_0204500" ] }, "reaction_10687396": { "compartment": "compartment_5460", "id": "reaction_10687396", "reactome": "R-PFA-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29362", "species_29376" ], "modifiers": [ [ "species_10687393", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10687406": { "compartment": "compartment_70101", "id": "reaction_10687406", "reactome": "R-PFA-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10687403", "catalyst" ] ], "additional_components": [ "C6S3E6", "PF3D7_1108300" ] }, "reaction_10690627": { "compartment": "compartment_876", "id": "reaction_10690627", "reactome": "R-PFA-203680", "name": "eNOS:NOSIP translocation from caveolae to intracellular compartments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690591" ], "products": [ "species_10690625" ], "modifiers": [], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "C0H4E6", "PF3D7_0518000", "C0H4E6", "PF3D7_0518000", "C0H553", "PF3D7_0923200", "species_917877", "species_216785", "species_73524", "species_29386", "species_29870" ] }, "reaction_10690593": { "compartment": "compartment_70101", "id": "reaction_10690593", "reactome": "R-PFA-203553", "name": "eNOS binds NOSIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690589", "species_10690485" ], "products": [ "species_10690591" ], "modifiers": [], "additional_components": [ "PF3D7_0518000", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "C0H4E6", "PF3D7_0518000" ] }, "reaction_10696674": { "compartment": "compartment_7660", "id": "reaction_10696674", "reactome": "R-PFA-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_5358610" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10687076", "catalyst" ] ], "additional_components": [ "PF3D7_1304100" ] }, "reaction_10696707": { "compartment": "compartment_7660", "id": "reaction_10696707", "reactome": "R-PFA-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10696653", "species_10696648" ], "products": [ "species_10696668" ], "modifiers": [], "additional_components": [ "PF3D7_0505500", "PF3D7_1427500", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582" ] }, "reaction_10696672": { "compartment": "compartment_7660", "id": "reaction_10696672", "reactome": "R-PFA-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696668", "species_5358514" ], "products": [ "species_10696670" ], "modifiers": [], "additional_components": [ "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582" ] }, "reaction_10696709": { "compartment": "compartment_7660", "id": "reaction_10696709", "reactome": "R-PFA-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696636", "species_10696641" ], "products": [ "species_10696643" ], "modifiers": [], "additional_components": [ "PF3D7_1117800", "PF3D7_0726300", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800" ] }, "reaction_10696661": { "compartment": "compartment_7660", "id": "reaction_10696661", "reactome": "R-PFA-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687014", "species_10696657", "species_10696643" ], "products": [ "species_10696659" ], "modifiers": [], "additional_components": [ "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696683": { "compartment": "compartment_7660", "id": "reaction_10696683", "reactome": "R-PFA-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696679", "species_10696663" ], "products": [ "species_10696681" ], "modifiers": [], "additional_components": [ "PF3D7_0725000", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "Q8IBK1", "PF3D7_0725000", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696666": { "compartment": "compartment_7660", "id": "reaction_10696666", "reactome": "R-PFA-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696659" ], "products": [ "species_10696663" ], "modifiers": [ [ "species_10696659", "catalyst" ] ], "additional_components": [ "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358", "Q8IBJ3", "PF3D7_0726300", "Q8IIJ0", "PF3D7_1117800", "P61074", "PF13_0328", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10696685": { "compartment": "compartment_7660", "id": "reaction_10696685", "reactome": "R-PFA-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10696670" ], "products": [ "species_113582", "species_10696657" ], "modifiers": [], "additional_components": [ "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_113582", "Q8ILI9", "PF3D7_1427500", "Q8I447", "PF3D7_0505500", "species_29358" ] }, "reaction_10690965": { "compartment": "compartment_70101", "id": "reaction_10690965", "reactome": "R-PFA-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10690953" ], "products": [ "species_10690957", "species_29420" ], "modifiers": [ [ "species_10690962", "catalyst" ] ], "additional_components": [ "Q7KQL3", "PF10_0203", "species_29420", "Q7KQL3", "PF10_0203", "species_29438", "PF3D7_1442900" ] }, "reaction_10696403": { "compartment": "compartment_171907", "id": "reaction_10696403", "reactome": "R-PFA-5229111", "name": "AP4 transports APP from trans-Golgi network to endosome lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10696386" ], "products": [ "species_10696400" ], "modifiers": [ [ "species_10696386", "catalyst" ] ], "additional_components": [ "Q8IIH2", "PF3D7_1119500", "Q8IBF8", "PF3D7_0730200", "Q8IFN5", "PF3D7_0423100", "Q8I3A8", "PF3D7_0904100", "Q8IFN5", "PF3D7_0423100", "Q8IIH2", "PF3D7_1119500", "Q8I3A8", "PF3D7_0904100", "Q8IBF8", "PF3D7_0730200", "Q8IIH2", "PF3D7_1119500", "Q8IBF8", "PF3D7_0730200", "Q8IFN5", "PF3D7_0423100", "Q8I3A8", "PF3D7_0904100" ] }, "reaction_10689478": { "compartment": "compartment_70101", "id": "reaction_10689478", "reactome": "R-PFA-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10689469", "species_10689473" ], "products": [ "species_10689444", "species_10689475" ], "modifiers": [ [ "species_10689469", "catalyst" ] ], "additional_components": [ "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300", "Q8I0P6", "PF3D7_1357000", "species_29420", "Q8I0P6", "PF3D7_1357000", "species_29438", "species_29420", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300" ] }, "reaction_10689471": { "compartment": "compartment_70101", "id": "reaction_10689471", "reactome": "R-PFA-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689467", "species_10689462", "species_10689456" ], "products": [ "species_10689469" ], "modifiers": [], "additional_components": [ "PF3D7_1338300", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "O97319", "PF3D7_0913200", "Q8I320", "PF3D7_0913200", "A0A5K1K967", "PF3D7_1338300" ] }, "reaction_10689366": { "compartment": "compartment_7660", "id": "reaction_10689366", "reactome": "R-PFA-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10688727" ], "products": [ "species_10688727" ], "modifiers": [], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10688732": { "compartment": "compartment_7660", "id": "reaction_10688732", "reactome": "R-PFA-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10688727" ], "products": [ "species_113582", "species_10688729" ], "modifiers": [ [ "species_10688727", "catalyst" ] ], "additional_components": [ "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8IJ31", "PF3D7_1037600", "Q8I4Y8", "PF3D7_1244200", "Q8IDG5", "PF3D7_1353500", "Q8IKK0", "PF3D7_1463700", "Q8I3Y3", "PF3D7_0512300", "Q8IL51", "PF3D7_1441900", "Q8I2H7", "PF3D7_0934100", "Q8IEG6", "PF3D7_1314900", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400" ] }, "reaction_10689360": { "compartment": "compartment_7660", "id": "reaction_10689360", "reactome": "R-PFA-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689305", "species_10688743" ], "products": [ "species_10689307" ], "modifiers": [], "additional_components": [ "PF3D7_1030000", "PF3D7_0610900", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000" ] }, "reaction_10689364": { "compartment": "compartment_7660", "id": "reaction_10689364", "reactome": "R-PFA-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689336" ], "products": [ "species_10689336" ], "modifiers": [], "additional_components": [ "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "C6KSQ9", "PF3D7_0606100", "Q9U0K9", "PF3D7_0407700", "Q8IJR8", "PF3D7_1012700", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77315", "PF3D7_0303300", "O96236", "PF3D7_0215700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I5R8", "PF3D7_1213700", "O77375", "PF3D7_0318200", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "C6KSV4", "PF3D7_0610900", "Q8IJA5", "PF3D7_1030000", "C6KSQ9", "PF3D7_0606100", "Q9U0K9", "PF3D7_0407700" ] }, "reaction_10689353": { "compartment": "compartment_7660", "id": "reaction_10689353", "reactome": "R-PFA-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689349", "species_10689344" ], "products": [ "species_10689351" ], "modifiers": [], "additional_components": [ "PF3D7_0517400", "PF3D7_1441400", "Q8IL56", "PF3D7_1441400", "Q8I3T4", "PF3D7_0517400" ] }, "reaction_10689133": { "compartment": "compartment_7660", "id": "reaction_10689133", "reactome": "R-PFA-110359", "name": "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10689116" ], "products": [ "species_10689130" ], "modifiers": [ [ "species_10689116", "catalyst" ] ], "additional_components": [ "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600", "O97240", "PF3D7_0305600" ] }, "reaction_10697443": { "compartment": "compartment_70101", "id": "reaction_10697443", "reactome": "R-PFA-5682377", "name": "LC3 de-lipidation by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697357" ], "products": [ "species_5681998", "species_10697347" ], "modifiers": [ [ "species_10697404", "catalyst" ] ], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "species_1500581", "Q8IJK2", "PF3D7_1019900", "Q8ILS3", "PF3D7_1417300" ] }, "reaction_10697409": { "compartment": "compartment_70101", "id": "reaction_10697409", "reactome": "R-PFA-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697363", "species_10697347" ], "products": [ "species_10697374" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697457": { "compartment": "compartment_5683628", "id": "reaction_10697457", "reactome": "R-PFA-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697357" ], "products": [ "species_10697455" ], "modifiers": [], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "species_1500581", "species_1500581", "Q8IJK2", "PF3D7_1019900" ] }, "reaction_10703360": { "compartment": "compartment_70101", "id": "reaction_10703360", "reactome": "R-PFA-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697365" ], "products": [ "species_10697459" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "C6S3K2", "PF3D7_1470000", "C6S3K2", "PF3D7_1470000", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697367": { "compartment": "compartment_70101", "id": "reaction_10697367", "reactome": "R-PFA-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697361", "species_10697363" ], "products": [ "species_10697365" ], "modifiers": [], "additional_components": [ "PF3D7_1470000", "Q8IIA3", "PF3D7_1126100", "Q8IIA3", "PF3D7_1126100", "C6S3K2", "PF3D7_1470000" ] }, "reaction_10697463": { "compartment": "compartment_70101", "id": "reaction_10697463", "reactome": "R-PFA-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697378" ], "products": [ "species_10697355", "species_10697363" ], "modifiers": [], "additional_components": [ "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697461": { "compartment": "compartment_70101", "id": "reaction_10697461", "reactome": "R-PFA-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697374", "species_10697359" ], "products": [ "species_10697376" ], "modifiers": [], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100", "PF3D7_0905700.2", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697381": { "compartment": "compartment_70101", "id": "reaction_10697381", "reactome": "R-PFA-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697376" ], "products": [ "species_10697378" ], "modifiers": [ [ "species_10697376", "catalyst" ] ], "additional_components": [ "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100", "Q8IIA3", "PF3D7_1126100", "Q8IJK2", "PF3D7_1019900", "C0H519", "PF3D7_0905700.2", "C0H519", "PF3D7_0905700.2", "Q8IJK2", "PF3D7_1019900", "Q8IIA3", "PF3D7_1126100" ] }, "reaction_10697407": { "compartment": "compartment_70101", "id": "reaction_10697407", "reactome": "R-PFA-5681987", "name": "LC3 is cleaved by ATG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697391" ], "products": [ "species_10697347" ], "modifiers": [ [ "species_10697404", "catalyst" ] ], "additional_components": [ "Q8IJK2", "PF3D7_1019900", "Q8IJK2", "PF3D7_1019900", "Q8ILS3", "PF3D7_1417300" ] }, "reaction_10703521": { "compartment": "compartment_70101", "id": "reaction_10703521", "reactome": "R-PFA-9641096", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703517", "species_10703502" ], "products": [ "species_10703519" ], "modifiers": [], "additional_components": [ "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600" ] }, "reaction_10703504": { "compartment": "compartment_70101", "id": "reaction_10703504", "reactome": "R-PFA-9641089", "name": "Parkin binds Ub:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703500", "species_10693227" ], "products": [ "species_10703502" ], "modifiers": [], "additional_components": [ "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "PF3D7_0303800", "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700" ] }, "reaction_10703543": { "compartment": "compartment_70101", "id": "reaction_10703543", "reactome": "R-PFA-9641109", "name": "PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703541" ], "products": [ "species_10703539", "species_10703523" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700" ] }, "reaction_10703563": { "compartment": "compartment_70101", "id": "reaction_10703563", "reactome": "R-PFA-9641111", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703519" ], "products": [ "species_10703561" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8IM64", "PF3D7_1402500", "Q7KQK2", "PF3D7_1402500", "Q8ID50", "PF3D7_1365900", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500" ] }, "reaction_10703565": { "compartment": "compartment_70101", "id": "reaction_10703565", "reactome": "R-PFA-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703561" ], "products": [ "species_10703541" ], "modifiers": [], "additional_components": [ "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "Q8IL07", "PF3D7_1446600", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "C6KTB1", "PF3D7_0627500", "O97226", "PF3D7_0303800", "Q8I3J4", "PF3D7_0527100", "O97241", "PF3D7_0305700", "C6KTB1", "PF3D7_0627500", "Q8I272", "PF3D7_1446600", "Q8I714", "PF3D7_1446600", "Q8IL07", "PF3D7_1446600" ] }, "reaction_10703283": { "compartment": "compartment_70101", "id": "reaction_10703283", "reactome": "R-PFA-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10687116", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10687426": { "compartment": "compartment_70101", "id": "reaction_10687426", "reactome": "R-PFA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10687423", "catalyst" ] ], "additional_components": [ "Q8I5L3", "PF3D7_1219900", "species_71067" ] }, "reaction_10699327": { "compartment": "compartment_70101", "id": "reaction_10699327", "reactome": "R-PFA-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10687116", "catalyst" ] ], "additional_components": [ "species_29926", "Q8IJS0", "PF3D7_1012500" ] }, "reaction_10690381": { "compartment": "compartment_70101", "id": "reaction_10690381", "reactome": "R-PFA-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10687423", "catalyst" ] ], "additional_components": [ "Q8I5L3", "PF3D7_1219900", "species_71067" ] }, "reaction_10697188": { "compartment": "compartment_70101", "id": "reaction_10697188", "reactome": "R-PFA-5661256", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5661264", "species_29364" ], "products": [ "species_29366", "species_5661268" ], "modifiers": [ [ "species_10697185", "catalyst" ] ], "additional_components": [ "PF3D7_1409100" ] }, "reaction_10692240": { "compartment": "compartment_7660", "id": "reaction_10692240", "reactome": "R-PFA-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692236", "species_450613" ], "products": [ "species_10692238" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10692472": { "compartment": "compartment_7660", "id": "reaction_10692472", "reactome": "R-PFA-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450605", "species_10692247" ], "products": [ "species_10692470" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10692476": { "compartment": "compartment_7660", "id": "reaction_10692476", "reactome": "R-PFA-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10692244", "species_517622" ], "products": [ "species_10692474" ], "modifiers": [], "additional_components": [ "PF3D7_0815600", "Q8IAZ3", "PF3D7_0815600" ] }, "reaction_10697334": { "compartment": "compartment_70101", "id": "reaction_10697334", "reactome": "R-PFA-5676966", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5687536", "species_71284" ], "products": [ "species_5687529", "species_71285" ], "modifiers": [ [ "species_10697331", "catalyst" ] ], "additional_components": [ "PF3D7_1432700" ] }, "reaction_10694769": { "compartment": "compartment_70101", "id": "reaction_10694769", "reactome": "R-PFA-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_111294", "species_111584" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10694772": { "compartment": "compartment_70101", "id": "reaction_10694772", "reactome": "R-PFA-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_111294", "species_109330" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10694766": { "compartment": "compartment_70101", "id": "reaction_10694766", "reactome": "R-PFA-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_111294", "species_29602" ], "modifiers": [ [ "species_10694763", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q8IBP3", "MAL7P1.110" ] }, "reaction_10702430": { "compartment": "compartment_7660", "id": "reaction_10702430", "reactome": "R-PFA-8866601", "name": "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_8866574" ], "products": [ "species_8866608", "species_8866567" ], "modifiers": [ [ "species_10702427", "catalyst" ], [ "species_29892", "catalyst" ] ], "additional_components": [ "Q8I533", "PF3D7_1239000", "species_216785" ] }, "reaction_10699367": { "compartment": "compartment_5460", "id": "reaction_10699367", "reactome": "R-PFA-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6788802" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10699364", "catalyst" ] ], "additional_components": [ "species_109395", "species_109386", "species_76577", "CHEBI:15918", "species_113582", "CHEBI:16174", "CHEBI:28846", "species_110094", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600" ] }, "reaction_10688358": { "compartment": "compartment_70101", "id": "reaction_10688358", "reactome": "R-PFA-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500071" ], "products": [ "species_29370", "species_500077" ], "modifiers": [ [ "species_10688355", "catalyst" ] ], "additional_components": [ "species_113578", "CHEBI:16192", "species_29420", "CHEBI:28862", "PF3D7_0928900" ] }, "reaction_10699375": { "compartment": "compartment_7660", "id": "reaction_10699375", "reactome": "R-PFA-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6788813" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10699372", "catalyst" ] ], "additional_components": [ "CHEBI:15918", "species_109395", "species_76577", "species_109386", "species_110094", "CHEBI:16174", "CHEBI:28846", "species_113582", "PF3D7_0110900" ] }, "reaction_10688302": { "compartment": "compartment_70101", "id": "reaction_10688302", "reactome": "R-PFA-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355", "species_109382" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10688299", "catalyst" ] ], "additional_components": [ "species_29926", "Q8I1R6", "PF3D7_0417200" ] }, "reaction_10692407": { "compartment": "compartment_5460", "id": "reaction_10692407", "reactome": "R-PFA-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113581", "species_482807" ], "products": [ "species_113593", "species_482803" ], "modifiers": [ [ "species_10692402", "catalyst" ] ], "additional_components": [ "species_110577", "species_29438", "species_500739", "species_29892", "species_29494", "species_110644", "species_30185", "species_30187", "CHEBI:18075", "species_29420", "CHEBI:28850", "CHEBI:28862", "species_205687", "CHEBI:16174", "CHEBI:28846", "species_110094", "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10689211": { "compartment": "compartment_70101", "id": "reaction_10689211", "reactome": "R-PFA-111746", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_10689189" ], "products": [ "species_10689186", "species_111745" ], "modifiers": [ [ "species_10689189", "catalyst" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "PF3D7_0306300" ] }, "reaction_10688312": { "compartment": "compartment_70101", "id": "reaction_10688312", "reactome": "R-PFA-73635", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_499997", "species_113592" ], "products": [ "species_29370", "species_499999" ], "modifiers": [ [ "species_10688309", "catalyst" ] ], "additional_components": [ "species_500742", "species_109366", "CHEBI:28850", "CHEBI:18075", "Q8I4S1", "PF3D7_1251300" ] }, "reaction_10689208": { "compartment": "compartment_70101", "id": "reaction_10689208", "reactome": "R-PFA-111742", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10689186" ], "products": [ "species_29356", "species_8866399", "species_10689189" ], "modifiers": [ [ "species_10689205", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688895": { "compartment": "compartment_70101", "id": "reaction_10688895", "reactome": "R-PFA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788778", "species_113592" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10688890", "catalyst" ] ], "additional_components": [ "species_76577", "species_109395", "CHEBI:15918", "species_109386", "species_113582", "CHEBI:28846", "CHEBI:16174", "species_110094", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600", "Q8I231", "PF3D7_0816900", "Q8IB06", "PF3D7_0816900" ] }, "reaction_10689214": { "compartment": "compartment_70101", "id": "reaction_10689214", "reactome": "R-PFA-111751", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10688320" ], "products": [ "species_10688318", "species_29356", "species_8866399" ], "modifiers": [ [ "species_10689205", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688893": { "compartment": "compartment_70101", "id": "reaction_10688893", "reactome": "R-PFA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_6788778", "species_113592" ], "modifiers": [ [ "species_10688890", "catalyst" ] ], "additional_components": [ "species_113582", "CHEBI:28846", "CHEBI:16174", "species_110094", "species_76577", "species_109395", "CHEBI:15918", "species_109386", "Q8IJV6", "PF3D7_1008900", "Q8I1T1", "PF3D7_0415600", "Q8I231", "PF3D7_0816900", "Q8IB06", "PF3D7_0816900" ] }, "reaction_10701181": { "compartment": "compartment_70101", "id": "reaction_10701181", "reactome": "R-PFA-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6806885" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10701178", "catalyst" ] ], "additional_components": [ "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10692419": { "compartment": "compartment_70101", "id": "reaction_10692419", "reactome": "R-PFA-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10692416", "catalyst" ] ], "additional_components": [ "Q8ILZ3", "PF3D7_1410200" ] }, "reaction_10688897": { "compartment": "compartment_70101", "id": "reaction_10688897", "reactome": "R-PFA-110141", "name": "(d)ADP + ADP <=> (d)AMP + ATP (AK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_500087" ], "products": [ "species_500088", "species_113592" ], "modifiers": [ [ "species_10688385", "catalyst" ] ], "additional_components": [ "species_113582", "CHEBI:16174", "species_76577", "species_109386", "PF3D7_0816900" ] }, "reaction_10688906": { "compartment": "compartment_70101", "id": "reaction_10688906", "reactome": "R-PFA-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10688903", "catalyst" ] ], "additional_components": [ "Q8I1T1", "PF3D7_0415600", "Q8IJV6", "PF3D7_1008900" ] }, "reaction_10692362": { "compartment": "compartment_70101", "id": "reaction_10692362", "reactome": "R-PFA-482621", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_482625" ], "products": [ "species_113592", "species_482627" ], "modifiers": [ [ "species_10692357", "catalyst" ] ], "additional_components": [ "species_29892", "species_110644", "species_30185", "species_29494", "species_30187", "species_110577", "species_500739", "species_29438", "species_205687", "CHEBI:28846", "CHEBI:16174", "species_29420", "CHEBI:28850", "CHEBI:28862", "CHEBI:18075", "species_110094", "Q8ID43", "PF3D7_1366500", "C6KSQ4", "PF3D7_0605600" ] }, "reaction_10689230": { "compartment": "compartment_70101", "id": "reaction_10689230", "reactome": "R-PFA-111804", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10688320" ], "products": [ "species_10688318", "species_29356", "species_8866399" ], "modifiers": [ [ "species_10689227", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0925500", "PF3D7_0925500", "Q8IJN8", "PF3D7_1405600", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688340": { "compartment": "compartment_70101", "id": "reaction_10688340", "reactome": "R-PFA-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10688337", "catalyst" ] ], "additional_components": [ "Q8ILZ3", "PF3D7_1410200" ] }, "reaction_10702420": { "compartment": "compartment_70101", "id": "reaction_10702420", "reactome": "R-PFA-8866405", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10689186" ], "products": [ "species_29356", "species_8866399", "species_10689189" ], "modifiers": [ [ "species_10689227", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "PF3D7_0306300", "PF3D7_0306300", "Q8IJN8", "PF3D7_1405600", "Q8IM38", "PF3D7_1405600", "CHEBI:29034", "Q8IL94", "PF3D7_1437200" ] }, "reaction_10688350": { "compartment": "compartment_7660", "id": "reaction_10688350", "reactome": "R-PFA-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742" ], "modifiers": [ [ "species_10688347", "catalyst" ] ], "additional_components": [ "Q8II92", "PF3D7_1127100" ] }, "reaction_10692257": { "compartment": "compartment_5462", "id": "reaction_10692257", "reactome": "R-PFA-450971", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113526", "species_113600" ], "products": [ "species_113563", "species_113529", "species_29362" ], "modifiers": [ [ "species_10692254", "catalyst" ] ], "additional_components": [ "Q8IKU3", "PF3D7_1453500" ] }, "reaction_10687520": { "compartment": "compartment_5460", "id": "reaction_10687520", "reactome": "R-PFA-71775", "name": "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_113548", "species_113525" ], "products": [ "species_29374", "species_113573", "species_113536" ], "modifiers": [ [ "species_10687517", "catalyst" ] ], "additional_components": [ "Q8IIR8", "PF3D7_1108500", "Q8ILE9", "PF3D7_1431600" ] }, "reaction_10687364": { "compartment": "compartment_5460", "id": "reaction_10687364", "reactome": "R-PFA-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113587", "species_113521" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10687361", "catalyst" ] ], "additional_components": [ "Q8I6U7", "PF3D7_1022500" ] }, "reaction_10687428": { "compartment": "compartment_5460", "id": "reaction_10687428", "reactome": "R-PFA-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_70958", "species_29362", "species_29376" ], "modifiers": [ [ "species_10687393", "catalyst" ] ], "additional_components": [ "Q8I6S5", "PF3D7_0820700", "species_29480", "CHEBI:17460", "Q8IEA6", "PF3D7_1320800", "Q8I5A0", "PF3D7_1232200", "species_29386" ] }, "reaction_10692267": { "compartment": "compartment_5460", "id": "reaction_10692267", "reactome": "R-PFA-450984", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_29938" ], "products": [ "species_113594", "species_113529", "species_113600", "species_29376" ], "modifiers": [ [ "species_10692264", "catalyst" ] ], "additional_components": [ "Q8I6T2", "PF3D7_1345700", "species_1981162" ] }, "reaction_10691918": { "compartment": "compartment_876", "id": "reaction_10691918", "reactome": "R-PFA-444008", "name": "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_114523", "species_74113" ], "products": [ "species_209914", "species_83910", "species_352022" ], "modifiers": [ [ "species_10691915", "catalyst" ] ], "additional_components": [ "PF3D7_0209600" ] }, "reaction_10687636": { "compartment": "compartment_7660", "id": "reaction_10687636", "reactome": "R-PFA-72095", "name": "Internal Methylation of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10687608" ], "products": [ "species_10687616" ], "modifiers": [ [ "species_10687633", "catalyst" ] ], "additional_components": [ "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "O77375", "PF3D7_0318200", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I1T2", "PF3D7_0415500", "A0A5K1K8X7", "PF3D7_1369500", "Q8I241", "PF3D7_0110400", "Q8ID59", "PF3D7_1364800", "Q8I5R8", "PF3D7_1213700", "O96236", "PF3D7_0215700", "O77315", "PF3D7_0303300", "Q8IER7", "PF13_0023", "Q8IDR2", "PF3D7_1342700", "O77375", "PF3D7_0318200", "O96150", "PF3D7_0205500", "Q8IC08", "PF3D7_0708100", "Q8IJC9", "PF3D7_1027400", "Q8I6Z2", "PF3D7_0729500", "Q8I567", "PF3D7_1235500", "Q8I5B2", "PF3D7_1230800" ] }, "reaction_10694523": { "compartment": "compartment_70101", "id": "reaction_10694523", "reactome": "R-PFA-2161500", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161525" ], "products": [ "species_2161185" ], "modifiers": [ [ "species_10694520", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] }, "reaction_10690615": { "compartment": "compartment_20699", "id": "reaction_10690615", "reactome": "R-PFA-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690542", "species_200993" ], "products": [ "species_10690595" ], "modifiers": [ [ "species_10690612", "catalyst" ] ], "additional_components": [ "PF3D7_0923200", "PF3D7_0923200", "Q8IIK6", "PF3D7_1322500", "A0A143ZYC1", "PF3D7_1322500", "Q8IE90", "PF3D7_1322500" ] }, "reaction_10690550": { "compartment": "compartment_20699", "id": "reaction_10690550", "reactome": "R-PFA-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690544" ], "products": [ "species_10690548" ], "modifiers": [], "additional_components": [ "species_917877", "species_216785", "species_73524", "species_29386", "C0H553", "PF3D7_0923200", "species_29870", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870" ] }, "reaction_10690629": { "compartment": "compartment_20699", "id": "reaction_10690629", "reactome": "R-PFA-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10690595" ], "products": [ "species_10690485" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386" ] }, "reaction_10690619": { "compartment": "compartment_70101", "id": "reaction_10690619", "reactome": "R-PFA-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_184174", "species_10690617" ], "products": [ "species_10690542" ], "modifiers": [], "additional_components": [ "PF3D7_0923200", "PF3D7_0923200" ] }, "reaction_10693934": { "compartment": "compartment_70101", "id": "reaction_10693934", "reactome": "R-PFA-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364" ], "products": [ "species_1222424", "species_29366" ], "modifiers": [ [ "species_10693929", "catalyst" ] ], "additional_components": [ "species_917877", "C0H553", "PF3D7_0923200", "species_216785", "species_73524", "species_29386", "species_29870", "species_1497857", "Q8I0V4", "PF3D7_1443900", "Q8IL32", "PF3D7_1443900", "Q8IC05", "PF3D7_1443900", "species_74016", "P62203", "PF14_0323" ] }, "reaction_10691747": { "compartment": "compartment_70101", "id": "reaction_10691747", "reactome": "R-PFA-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10691712", "species_429974" ], "products": [ "species_10691714" ], "modifiers": [], "additional_components": [ "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200" ] }, "reaction_10691745": { "compartment": "compartment_70101", "id": "reaction_10691745", "reactome": "R-PFA-429860", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10691714" ], "products": [ "species_10691716", "species_430004" ], "modifiers": [ [ "species_10691742", "catalyst" ] ], "additional_components": [ "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "C0H4W2", "PF3D7_0819900", "Q8IE68", "PF3D7_1325000", "Q8I3Q7", "PF3D7_0520300", "Q8IIT3", "PF3D7_1107000", "Q8IIB9", "PF3D7_1124400", "Q8IL38", "PF3D7_1443300", "Q8I5V6", "PF3D7_1209200", "Q8IEM5", "PF3D7_1308900", "C6KSR4", "PF3D7_0606600", "Q8IJ85", "PF3D7_1032100", "O97285", "PF3D7_0320800" ] }, "reaction_10689987": { "compartment": "compartment_876", "id": "reaction_10689987", "reactome": "R-PFA-189222", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189049" ], "products": [ "species_29532" ], "modifiers": [ [ "species_10689984", "catalyst" ] ], "additional_components": [ "Q7KWJ5", "PF3D7_0919500", "Q8I2V8", "PF3D7_0919500" ] }, "reaction_10689998": { "compartment": "compartment_876", "id": "reaction_10689998", "reactome": "R-PFA-189242", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189246" ], "products": [ "species_189219" ], "modifiers": [ [ "species_10689995", "catalyst" ] ], "additional_components": [ "species_70115", "CHEBI:17118", "species_29532", "CHEBI:17118", "species_70115", "species_29532", "Q8I2V8", "PF3D7_0919500", "Q7KWJ5", "PF3D7_0919500" ] }, "reaction_10697522": { "compartment": "compartment_12045", "id": "reaction_10697522", "reactome": "R-PFA-5685649", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10697518" ], "products": [ "species_10697520" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10703245": { "compartment": "compartment_12045", "id": "reaction_10703245", "reactome": "R-PFA-8961021", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703241" ], "products": [ "species_10703243" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10703484": { "compartment": "compartment_12045", "id": "reaction_10703484", "reactome": "R-PFA-9624778", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10703243" ], "products": [ "species_10703482" ], "modifiers": [], "additional_components": [ "O96246", "PF3D7_0216800", "O96246", "PF3D7_0216800" ] }, "reaction_10691053": { "compartment": "compartment_984", "id": "reaction_10691053", "reactome": "R-PFA-374919", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10691048", "catalyst" ] ], "additional_components": [ "Q8I611", "PF3D7_1203400" ] } }, "mod_collapsed_pathways": {}, "degree_dictionary": { "reaction_10697020": 6, "species_70106": 58, "species_29364": 35, "species_70113": 10, "species_29366": 36, "species_5652213": 1, "species_10690215": 3, "PF3D7_1409100": 5, "reaction_10686578": 6, "species_29358": 36, "species_10686546": 13, "Q8I469": 4, "PF3D7_0503200": 4, "A0A5K1K8V1": 5, "PF3D7_1334100": 1, "O96237": 5, "PF3D7_0215800": 1, "Q8IC17": 5, "PF3D7_0705300": 1, "Q8I5T7": 3, "PF3D7_1211300": 1, "Q8I615": 3, "PF3D7_1203000": 5, "Q8I3J5": 4, "PF3D7_0527000": 2, "Q8IDF0": 5, "PF3D7_1355100": 1, "Q8IEE5": 5, "PF3D7_1317100": 1, "Q8IC16": 5, "PF3D7_0705400": 1, "Q8I5T4": 4, "PF3D7_1211700": 2, "Q8ILR7": 4, "PF3D7_1417800": 2, "species_10686556": 12, "species_113582": 34, 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